TreeWAS – Variant ID: rs12344488

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I34.0 Mitral (valve) insufficiency	0.000	0.970	0.030
H36.0 Diabetic retinopathy	0.023	0.977	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.978	0.022
I34.1 Mitral (valve) prolapse	0.000	0.978	0.022
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.984	0.016
H36 Retinal disorders in diseases classified elsewhere	0.015	0.985	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.985	0.015
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.986	0.014
Y95 Nosocomial condition	0.013	0.987	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.011	0.989	0.000
H30-H36 Disorders of choroid and retina	0.010	0.990	0.000
H34 Retinal vascular occlusions	0.009	0.991	0.000
H33 Retinal detachments and breaks	0.009	0.991	0.000
H34.8 Other retinal vascular occlusions	0.008	0.992	0.000
H31 Other disorders of choroid	0.008	0.992	0.000
H33.4 Traction detachment of retina	0.008	0.992	0.000
H30 Chorioretinal inflammation	0.007	0.993	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.007	0.993	0.000
H31.0 Chorioretinal scars	0.007	0.993	0.000
H33.0 Retinal detachment with retinal break	0.007	0.993	0.000
H33.1 Retinoschisis and retinal cysts	0.007	0.993	0.000
H34.1 Central retinal artery occlusion	0.007	0.993	0.000
H34.9 Retinal vascular occlusion, unspecified	0.006	0.993	0.000
H34.0 Transient retinal artery occlusion	0.006	0.993	0.000
H34.2 Other retinal artery occlusions	0.006	0.994	0.000
H31.8 Other specified disorders of choroid	0.006	0.994	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.994	0.006
H31.9 Disorder of choroid, unspecified	0.006	0.994	0.000
H31.4 Choroidal detachment	0.006	0.994	0.000
H31.3 Choroidal haemorrhage and rupture	0.006	0.994	0.000
H31.2 Hereditary choroidal dystrophy	0.006	0.994	0.000
H31.1 Choroidal degeneration	0.006	0.994	0.000
H33.3 Retinal breaks without detachment	0.006	0.994	0.000
H33.2 Serous retinal detachment	0.006	0.994	0.000
H30.9 Chorioretinal inflammation, unspecified	0.006	0.994	0.000
F33 Recurrent depressive disorder	0.000	0.994	0.006
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.006	0.994	0.000
H30.8 Other chorioretinal inflammations	0.005	0.994	0.000
H30.2 Posterior cyclitis	0.005	0.994	0.000
H30.1 Disseminated chorioretinal inflammation	0.005	0.994	0.000
H30.0 Focal chorioretinal inflammation	0.005	0.994	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.005	0.995	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H33.5 Other retinal detachments	0.005	0.995	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.995	0.005
E11.3 With ophthalmic complications	0.005	0.995	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.995	0.005
Z36.8 Other antenatal screening	0.000	0.995	0.005
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.995	0.005
F31 Bipolar affective disorder	0.000	0.995	0.005
Z36 Antenatal screening	0.000	0.996	0.004
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.996	0.004
F33.8 Other recurrent depressive disorders	0.000	0.996	0.004
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.996	0.004
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.996	0.004
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.004	0.996	0.000
Y98 Lifestyle-related condition	0.004	0.996	0.000
Y97 Environmental-pollution-related condition	0.004	0.996	0.000
Y96 Work-related condition	0.004	0.996	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.004	0.996	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
F30-F39 Mood [affective] disorders	0.000	0.996	0.004
Z36.9 Antenatal screening, unspecified	0.000	0.996	0.004
E14.3 With ophthalmic complications	0.004	0.996	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.996	0.004
Z87.1 Personal history of diseases of the digestive system	0.004	0.996	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.004
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
M13.94 Arthritis, unspecified (Hand)	0.004	0.996	0.000
F31.8 Other bipolar affective disorders	0.000	0.996	0.003
F31.7 Bipolar affective disorder, currently in remission	0.000	0.996	0.003
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.996	0.003
F30 Manic episode	0.000	0.996	0.003
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.996	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.996	0.003
Z36.5 Antenatal screening for isoimmunisation	0.000	0.997	0.003
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.997	0.003
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.997	0.003
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
Y90.9 Presence of alcohol in blood, level not specified	0.003	0.997	0.000
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.003	0.997	0.000
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.003	0.997	0.000
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.003	0.997	0.000
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.003	0.997	0.000
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.003	0.997	0.000
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.003	0.997	0.000
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.003	0.997	0.000
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.003	0.997	0.000
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.003	0.997	0.000
Y91.3 Very severe alcohol intoxication	0.003	0.997	0.000
Y91.2 Severe alcohol intoxication	0.003	0.997	0.000
Y91.1 Moderate alcohol intoxication	0.003	0.997	0.000
Y91.0 Mild alcohol intoxication	0.003	0.997	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.003	0.997	0.000
F38 Other mood [affective] disorders	0.000	0.997	0.003
F39 Unspecified mood [affective] disorder	0.000	0.997	0.003
J38.3 Other diseases of vocal cords	0.003	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.003	0.997	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
H18 Other disorders of cornea	0.003	0.997	0.000
F30.0 Hypomania	0.000	0.997	0.003
H90 Conductive and sensorineural hearing loss	0.003	0.997	0.000
F32 Depressive episode	0.000	0.997	0.003
F32.1 Moderate depressive episode	0.000	0.997	0.003
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.997	0.003
F34 Persistent mood [affective] disorders	0.000	0.997	0.003
Z12.1 Special screening examination for neoplasm of intestinal tract	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
F30.8 Other manic episodes	0.000	0.997	0.003
F30.2 Mania with psychotic symptoms	0.000	0.997	0.003
F30.1 Mania without psychotic symptoms	0.000	0.997	0.003
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
H90.0 Conductive hearing loss, bilateral	0.003	0.997	0.000
Z98.0 Intestinal bypass and anastomosis status	0.003	0.997	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.997	0.002
F38.1 Other recurrent mood [affective] disorders	0.000	0.997	0.002
F38.0 Other single mood [affective] disorders	0.000	0.997	0.002
E14 Unspecified diabetes mellitus	0.003	0.997	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.003	0.997	0.000
N93.0 Postcoital and contact bleeding	0.000	0.997	0.003
M89.8 Other specified disorders of bone	0.003	0.997	0.000
M89.3 Hypertrophy of bone	0.002	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
H18.7 Other corneal deformities	0.002	0.997	0.000
H18.6 Keratoconus	0.002	0.997	0.000
H18.3 Changes in corneal membranes	0.002	0.997	0.000
H18.2 Other corneal oedema	0.002	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
K02.9 Dental caries, unspecified	0.000	0.998	0.002
N03.9 Unspecified	0.000	0.998	0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
M43.02 Spondylolysis (Cervical region)	0.002	0.998	0.000
F32.8 Other depressive episodes	0.000	0.998	0.002
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.998	0.002
F34.8 Other persistent mood [affective] disorders	0.000	0.998	0.002
F34.0 Cyclothymia	0.000	0.998	0.002
C44.7 Skin of lower limb, including hip	0.000	0.998	0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
E11 Non-insulin-dependent diabetes mellitus	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
E10.2 With renal complications	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
E10.4 With neurological complications	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
E10.6 With other specified complications	0.002	0.998	0.000
E14.8 With unspecified complications	0.002	0.998	0.000
E14.7 With multiple complications	0.002	0.998	0.000
E14.6 With other specified complications	0.002	0.998	0.000
E14.5 With peripheral circulatory complications	0.002	0.998	0.000
E14.4 With neurological complications	0.002	0.998	0.000
E14.2 Withrenal complications	0.002	0.998	0.000
E14.1 With ketoacidosis	0.002	0.998	0.000
E14.0 With coma	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
E11.1 With ketoacidosis	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
R17 Unspecified jaundice	0.000	0.998	0.002
F34.1 Dysthymia	0.000	0.998	0.002
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
E10.1 With ketoacidosis	0.002	0.998	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.998	0.002
E11.8 With unspecified complications	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
E10.7 With multiple complications	0.002	0.998	0.000
E11.7 With multiple complications	0.002	0.998	0.000
M43.0 Spondylolysis	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
E11.2 With renal complications	0.002	0.998	0.000
E10.0 With coma	0.002	0.998	0.000
E11.6 With other specified complications	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
E12 Malnutrition-related diabetes mellitus	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
Z12 Special screening examination for neoplasms	0.002	0.998	0.000
M43.09 Spondylolysis (Site unspecified)	0.002	0.998	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.002	0.998	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.002	0.998	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.002	0.998	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.002	0.998	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
S00.8 Superficial injury of other parts of head	0.000	0.998	0.002
Z12.0 Special screening examination for neoplasm of stomach	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
N18.9 Chronic renal failure, unspecified	0.002	0.998	0.000
S71.1 Open wound of thigh	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.998	0.002
E11.0 With coma	0.002	0.998	0.000
G35 Multiple sclerosis	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.002	0.998	0.000
M25.57 Pain in joint (Ankle and foot)	0.002	0.998	0.000
D37.4 Colon	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.002	0.998	0.000
M86-M90 Other osteopathies	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.002	0.998	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.002	0.998	0.000
M43.04 Spondylolysis (Thoracic region)	0.002	0.998	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.002	0.998	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
M88.8 Paget's disease of other bones	0.001	0.998	0.000
M88.0 Paget's disease of skull	0.001	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.998	0.002
Z12.8 Special screening examination for neoplasm of other sites	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
J31.0 Chronic rhinitis	0.002	0.998	0.000
J93 Pneumothorax	0.002	0.998	0.000
E12.9 Without complications	0.001	0.998	0.000
E12.8 With unspecified complications	0.001	0.998	0.000
E12.7 With multiple complications	0.001	0.998	0.000
E12.6 With other specified complications	0.001	0.998	0.000
E12.5 With peripheral circulatory complications	0.001	0.998	0.000
E12.4 With neurological complications	0.001	0.998	0.000
E12.3 With ophthalmic complications	0.001	0.998	0.000
E12.2 With renal complications	0.001	0.998	0.000
E12.1 With ketoacidosis	0.001	0.998	0.000
E12.0 With coma	0.001	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
Z12.3 Special screening examination for neoplasm of breast	0.001	0.998	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.001	0.998	0.000
J18.1 Lobar pneumonia, unspecified	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.001	0.998	0.000
H92 Otalgia and effusion of ear	0.002	0.998	0.000
E11.5 With peripheral circulatory complications	0.001	0.998	0.000
H74.4 Polyp of middle ear	0.001	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
M87 Osteonecrosis	0.001	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.001	0.998	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.001	0.998	0.000
H17 Corneal scars and opacities	0.001	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.001	0.998	0.000
H16.9 Keratitis, unspecified	0.001	0.998	0.000
H16 Keratitis	0.001	0.998	0.000
H69 Other disorders of Eustachian tube	0.001	0.998	0.000
H15.8 Other disorders of sclera	0.001	0.998	0.000
H15.1 Episcleritis	0.001	0.998	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.001	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.001	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.001
H57 Other disorders of eye and adnexa	0.001	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.999	0.000
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.001	0.999	0.000
M88.09 Paget's disease of skull-Site unspec	0.001	0.999	0.000
M88.08 Paget's disease of skull-Other	0.001	0.999	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.001	0.999	0.000
M88.06 Paget's disease of skull-Lower Leg	0.001	0.999	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.001	0.999	0.000
M88.04 Paget's disease of skull-Hand	0.001	0.999	0.000
M88.03 Paget's disease of skull-Forearm	0.001	0.999	0.000
M88.02 Paget's disease of skull-Upper arm	0.001	0.999	0.000
M88.01 Paget's disease of skull-Shldr region	0.001	0.999	0.000
M88.00 Paget's disease of skull-Mult sites	0.001	0.999	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.001	0.999	0.000
M88.88 Paget's disease of other bones (Other)	0.001	0.999	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.001	0.999	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.001	0.999	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.001	0.999	0.000
M88.84 Paget's disease of other bones (Hand)	0.001	0.999	0.000
M88.83 Paget's disease of other bones (Forearm)	0.001	0.999	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.001	0.999	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.001	0.999	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.001	0.999	0.000
E13.8 With unspecified complications	0.001	0.999	0.000
E13.7 With multiple complications	0.001	0.999	0.000
E13.6 With other specified complications	0.001	0.999	0.000
E13.5 With peripheral circulatory complications	0.001	0.999	0.000
E13.4 With neurological complications	0.001	0.999	0.000
E13.3 With ophthalmic complications	0.001	0.999	0.000
E13.2 With renal complications	0.001	0.999	0.000
E13.1 With ketoacidosis	0.001	0.999	0.000
E13.0 With coma	0.001	0.999	0.000
G47.3 Sleep apnoea	0.000	0.999	0.001
H15.9 Disorder of sclera, unspecified	0.001	0.999	0.000
H15.0 Scleritis	0.001	0.999	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.999	0.001
H93 Other disorders of ear, not elsewhere classified	0.001	0.999	0.000
H92.1 Otorrhoea	0.001	0.999	0.000
J93.0 Spontaneous tension pneumothorax	0.001	0.999	0.000
K02.8 Other dental caries	0.000	0.999	0.001
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.999	0.000
H72.1 Attic perforation of tympanic membrane	0.001	0.999	0.000
H92.2 Otorrhagia	0.001	0.999	0.000
H95.1 Other disorders following mastoidectomy	0.001	0.999	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.001	0.999	0.000
M86 Osteomyelitis	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
H17.8 Other corneal scars and opacities	0.001	0.999	0.000
H17.1 Other central corneal opacity	0.001	0.999	0.000
H17.0 Adherent leukoma	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.999	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.001	0.999	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.001	0.999	0.000
M87.8 Other osteonecrosis	0.001	0.999	0.000
M87.3 Other secondary osteonecrosis	0.001	0.999	0.000
M87.1 Osteonecrosis due to drugs	0.001	0.999	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.999	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.999	0.000
M90.6 Osteitis deformans in neoplastic disease	0.001	0.999	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.999	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.999	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.999	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.999	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.001	0.999	0.000
M90.0 Tuberculosis of bone	0.001	0.999	0.000
K02 Dental caries	0.000	0.999	0.001
H16.8 Other keratitis	0.001	0.999	0.000
H16.4 Corneal neovascularisation	0.001	0.999	0.000
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
H72.0 Central perforation of tympanic membrane	0.001	0.999	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.999	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
J38.5 Laryngeal spasm	0.001	0.999	0.000
K70.9 Alcoholic liver disease, unspecified	0.001	0.999	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
C44.4 Skin of scalp and neck	0.001	0.999	0.000
H57.0 Anomalies of pupillary function	0.001	0.999	0.000
M87.9 Osteonecrosis, unspecified	0.001	0.999	0.000
C90.0 Multiple myeloma	0.001	0.999	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.001	0.999	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.001	0.999	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.001	0.999	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.001	0.999	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.999	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
J38.1 Polyp of vocal cord and larynx	0.001	0.999	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.999	0.001
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
H55-H59 Other disorders of eye and adnexa	0.001	0.999	0.000
H65-H75 Diseases of middle ear and mastoid	0.001	0.999	0.000
H92.0 Otalgia	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations