TreeWAS – Variant ID: rs12345625

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54.5 Low back pain	0.115	0.885	0.000
M54.59 Low back pain (Site unspecified)	0.113	0.887	0.000
M54 Dorsalgia	0.108	0.892	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.108	0.892	0.000
M54.56 Low back pain (Lumbar region)	0.107	0.893	0.000
M54.9 Dorsalgia, unspecified	0.106	0.894	0.000
M54.50 Low back pain (Multiple sites in spine)	0.095	0.905	0.000
M54.57 Low back pain (Lumbosacral region)	0.091	0.909	0.000
M54.3 Sciatica	0.090	0.910	0.000
M54.1 Radiculopathy	0.083	0.917	0.000
M54.55 Low back pain (Thoracolumbar region)	0.083	0.917	0.000
M54.54 Low back pain-Thoracic	0.083	0.917	0.000
M54.53 Low back pain-Cervicothoracic	0.083	0.917	0.000
M54.52 Low back pain-Cervical	0.083	0.917	0.000
M54.51 Low back pain-Occipit-atl-axl	0.083	0.917	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.083	0.917	0.000
M54.36 Sciatica (Lumbar region)	0.081	0.919	0.000
M54.4 Lumbago with sciatica	0.080	0.920	0.000
M54.6 Pain in thoracic spine	0.079	0.921	0.000
M54.8 Other dorsalgia	0.078	0.922	0.000
M54.0 Panniculitis affecting regions of neck and back	0.078	0.922	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.076	0.923	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.076	0.923	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.076	0.923	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.076	0.923	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.076	0.923	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.076	0.923	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.074	0.926	0.000
M54.2 Cervicalgia	0.073	0.926	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.073	0.927	0.000
M54.16 Radiculopathy (Lumbar region)	0.065	0.935	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.065	0.935	0.000
M54.37 Sciatica (Lumbosacral region)	0.065	0.935	0.000
M54.35 Sciatica (Thoracolumbar region)	0.065	0.935	0.000
M54.34 Sciatica-Thoracic	0.065	0.935	0.000
M54.33 Sciatica-Cervicothoracic	0.065	0.935	0.000
M54.32 Sciatica-Cervical	0.065	0.935	0.000
M54.31 Sciatica-Occipit-atl-axl	0.065	0.935	0.000
M54.30 Sciatica (Multiple sites in spine)	0.065	0.935	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.065	0.935	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.064	0.936	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.060	0.940	0.000
M54.19 Radiculopathy (Site unspecified)	0.060	0.940	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.060	0.940	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.060	0.940	0.000
M54.14 Radiculopathy (Thoracic region)	0.060	0.940	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.060	0.940	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.060	0.940	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.060	0.940	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.058	0.942	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.058	0.942	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.058	0.942	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.058	0.942	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.058	0.942	0.000
M54.44 Lumbago with sciatica-Thoracic	0.058	0.942	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.058	0.942	0.000
M54.42 Lumbago with sciatica-Cervical	0.058	0.942	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.058	0.942	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.058	0.942	0.000
M54.69 Pain in thoracic spine-Site unspe	0.057	0.943	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.057	0.943	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.057	0.943	0.000
M54.66 Pain in thoracic spine-Lumbar	0.057	0.943	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.057	0.943	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.057	0.943	0.000
M54.62 Pain in thoracic spine-Cervical	0.057	0.943	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.057	0.943	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.057	0.943	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.056	0.944	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.056	0.944	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.056	0.944	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.056	0.944	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.056	0.944	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.056	0.944	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.056	0.944	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.056	0.944	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.056	0.944	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.056	0.944	0.000
M54.89 Other dorsalgia (Site unspecified)	0.056	0.944	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.056	0.944	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.056	0.944	0.000
M54.86 Other dorsalgia (Lumbar region)	0.056	0.944	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.056	0.944	0.000
M54.84 Other dorsalgia (Thoracic region)	0.056	0.944	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.056	0.944	0.000
M54.82 Other dorsalgia (Cervical region)	0.056	0.944	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.056	0.944	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.056	0.944	0.000
M54.12 Radiculopathy (Cervical region)	0.054	0.946	0.000
M54.39 Sciatica (Site unspecified)	0.053	0.947	0.000
M54.29 Cervicalgia-Site unspe	0.053	0.947	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.053	0.947	0.000
M54.27 Cervicalgia-Lumbosacral	0.053	0.947	0.000
M54.26 Cervicalgia-Lumbar	0.053	0.947	0.000
M54.25 Cervicalgia-Thoracolumbar	0.053	0.947	0.000
M54.24 Cervicalgia-Thoracic	0.053	0.947	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.053	0.947	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.053	0.947	0.000
M54.20 Cervicalgia-Mult site	0.053	0.947	0.000
M54.22 Cervicalgia (Cervical region)	0.048	0.952	0.000
G43.9 Migraine, unspecified	0.000	0.953	0.047
E11.9 Without complications	0.023	0.977	0.000
E11 Non-insulin-dependent diabetes mellitus	0.022	0.978	0.000
G43 Migraine	0.000	0.979	0.021
E10-E14 Diabetes mellitus	0.019	0.981	0.000
M50-M54 Other dorsopathies	0.019	0.981	0.000
E11.3 With ophthalmic complications	0.019	0.981	0.000
E10 Insulin-dependent diabetes mellitus	0.018	0.981	0.000
E10.3 With ophthalmic complications	0.018	0.982	0.000
E11.6 With other specified complications	0.018	0.982	0.000
E89.0 Postprocedural hypothyroidism	0.018	0.982	0.000
E11.5 With peripheral circulatory complications	0.017	0.983	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.017	0.983	0.000
E70-E90 Metabolic disorders	0.016	0.984	0.000
E11.8 With unspecified complications	0.016	0.984	0.000
E11.7 With multiple complications	0.016	0.984	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.984	0.015
G43.8 Other migraine	0.000	0.985	0.015
G43.3 Complicated migraine	0.000	0.985	0.015
G43.2 Status migrainosus	0.000	0.985	0.015
G43.0 Migraine without aura [common migraine]	0.000	0.985	0.015
E80 Disorders of porphyrin and bilirubin metabolism	0.015	0.985	0.000
E11.0 With coma	0.015	0.985	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.015	0.985	0.000
E11.1 With ketoacidosis	0.015	0.985	0.000
E10.2 With renal complications	0.015	0.985	0.000
E80.4 Gilbert's syndrome	0.015	0.985	0.000
E11.4 With neurological complications	0.015	0.985	0.000
E78.5 Hyperlipidaemia, unspecified	0.015	0.985	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.014	0.986	0.000
E10.1 With ketoacidosis	0.014	0.986	0.000
E11.2 With renal complications	0.014	0.986	0.000
E12 Malnutrition-related diabetes mellitus	0.014	0.986	0.000
E88 Other metabolic disorders	0.014	0.986	0.000
E85 Amyloidosis	0.013	0.986	0.000
E10.8 With unspecified complications	0.013	0.986	0.000
E10.7 With multiple complications	0.013	0.986	0.000
E10.6 With other specified complications	0.013	0.986	0.000
E10.0 With coma	0.013	0.986	0.000
E10.9 Without complications	0.014	0.986	0.000
M53 Other dorsopathies, not elsewhere classified	0.013	0.987	0.000
E13 Other specified diabetes mellitus	0.013	0.987	0.000
I50.1 Left ventricular failure	0.013	0.987	0.000
E73 Lactose intolerance	0.013	0.987	0.000
E10.4 With neurological complications	0.012	0.987	0.000
E74 Other disorders of carbohydrate metabolism	0.012	0.988	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.012	0.988	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.012	0.988	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.012	0.988	0.000
E89.5 Postprocedural testicular hypofunction	0.012	0.988	0.000
E89.4 Postprocedural ovarian failure	0.012	0.988	0.000
E89.3 Postprocedural hypopituitarism	0.012	0.988	0.000
E89.2 Postprocedural hypoparathyroidism	0.012	0.988	0.000
E89.1 Postprocedural hypoinsulinaemia	0.012	0.988	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.012	0.988	0.000
E20-E35 Disorders of other endocrine glands	0.012	0.988	0.000
E10.5 With peripheral circulatory complications	0.012	0.988	0.000
E78.1 Pure hyperglyceridaemia	0.012	0.988	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.012	0.988	0.000
E00-E07 Disorders of thyroid gland	0.012	0.988	0.000
E85.4 Organ-limited amyloidosis	0.012	0.988	0.000
E84 Cystic fibrosis	0.012	0.988	0.000
E79 Disorders of purine and pyrimidine metabolism	0.012	0.988	0.000
E77 Disorders of glycoprotein metabolism	0.012	0.988	0.000
E76 Disorders of glycosaminoglycan metabolism	0.012	0.988	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.012	0.988	0.000
E72 Other disorders of amino-acid metabolism	0.012	0.988	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.012	0.988	0.000
E70 Disorders of aromatic amino-acid metabolism	0.012	0.988	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.012	0.988	0.000
E78.8 Other disorders of lipoprotein metabolism	0.011	0.988	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.011	0.989	0.000
E80.6 Other disorders of bilirubin metabolism	0.011	0.989	0.000
E80.5 Crigler-Najjar syndrome	0.011	0.989	0.000
E80.3 Defects of catalase and peroxydase	0.011	0.989	0.000
E80.2 Other porphyria	0.011	0.989	0.000
E80.1 Porphyria cutanea tarda	0.011	0.989	0.000
E80.0 Hereditary erythropoietic porphyria	0.011	0.989	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.011	0.989	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.011	0.989	0.000
E07 Other disorders of thyroid	0.011	0.989	0.000
E88.2 Lipomatosis, not elsewhere classified	0.011	0.989	0.000
E40-E46 Malnutrition	0.011	0.989	0.000
E07.9 Disorder of thyroid, unspecified	0.011	0.989	0.000
E78.6 Lipoprotein deficiency	0.010	0.989	0.000
E78.4 Other hyperlipidaemia	0.010	0.989	0.000
E78.3 Hyperchylomicronaemia	0.010	0.989	0.000
E73.9 Lactose intolerance, unspecified	0.010	0.989	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.011	0.989	0.000
E12.9 Without complications	0.010	0.990	0.000
E12.8 With unspecified complications	0.010	0.990	0.000
E12.7 With multiple complications	0.010	0.990	0.000
E12.6 With other specified complications	0.010	0.990	0.000
E12.5 With peripheral circulatory complications	0.010	0.990	0.000
E12.4 With neurological complications	0.010	0.990	0.000
E12.3 With ophthalmic complications	0.010	0.990	0.000
E12.2 With renal complications	0.010	0.990	0.000
E12.1 With ketoacidosis	0.010	0.990	0.000
E12.0 With coma	0.010	0.990	0.000
E14 Unspecified diabetes mellitus	0.010	0.990	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
E88.9 Metabolic disorder, unspecified	0.010	0.990	0.000
E88.8 Other specified metabolic disorders	0.010	0.990	0.000
E88.3 Tumour lysis syndrome	0.010	0.990	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.010	0.990	0.000
E85.9 Amyloidosis, unspecified	0.010	0.990	0.000
E85.8 Other amyloidosis	0.010	0.990	0.000
E85.3 Secondary systemic amyloidosis	0.010	0.990	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.010	0.990	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.010	0.990	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.010	0.990	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.010	0.990	0.000
M53.9 Dorsopathy, unspecified	0.010	0.990	0.000
M53.8 Other specified dorsopathies	0.010	0.990	0.000
M53.2 Spinal instabilities	0.010	0.990	0.000
M53.1 Cervicobrachial syndrome	0.010	0.990	0.000
M53.0 Cervicocranial syndrome	0.010	0.990	0.000
E06 Thyroiditis	0.010	0.990	0.000
E20 Hypoparathyroidism	0.010	0.990	0.000
E13.8 With unspecified complications	0.009	0.990	0.000
E13.7 With multiple complications	0.009	0.990	0.000
E13.6 With other specified complications	0.009	0.990	0.000
E13.5 With peripheral circulatory complications	0.009	0.990	0.000
E13.4 With neurological complications	0.009	0.990	0.000
E13.3 With ophthalmic complications	0.009	0.990	0.000
E13.2 With renal complications	0.009	0.990	0.000
E13.1 With ketoacidosis	0.009	0.990	0.000
E13.0 With coma	0.009	0.990	0.000
M50 Cervical disk disorders	0.009	0.990	0.000
E73.8 Other lactose intolerance	0.009	0.990	0.000
E73.1 Secondary lactase deficiency	0.009	0.990	0.000
E73.0 Congenital lactase deficiency	0.009	0.990	0.000
E16 Other disorders of pancreatic internal secretion	0.009	0.990	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.009	0.991	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.991	0.009
E21.0 Primary hyperparathyroidism	0.009	0.991	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.009	0.991	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.009	0.991	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.009	0.991	0.000
E74.2 Disorders of galactose metabolism	0.009	0.991	0.000
E74.1 Disorders of fructose metabolism	0.009	0.991	0.000
E74.0 Glycogen storage disease	0.009	0.991	0.000
E27 Other disorders of adrenal gland	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
I31.3 Pericardial effusion (noninflammatory)	0.009	0.991	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.009	0.991	0.000
E34 Other endocrine disorders	0.009	0.991	0.000
E32 Diseases of thymus	0.009	0.991	0.000
E31 Polyglandular dysfunction	0.009	0.991	0.000
E30 Disorders of puberty, not elsewhere classified	0.009	0.991	0.000
E25 Adrenogenital disorders	0.009	0.991	0.000
E24 Cushing's syndrome	0.009	0.991	0.000
E26 Hyperaldosteronism	0.009	0.991	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.009	0.991	0.000
E00 Congenital iodine-deficiency syndrome	0.009	0.991	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.009	0.991	0.000
E15 Nondiabetic hypoglycaemic coma	0.009	0.991	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.008	0.991	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.008	0.991	0.000
E70.3 Albinism	0.008	0.991	0.000
E70.2 Disorders of tyrosine metabolism	0.008	0.991	0.000
E70.1 Other hyperphenylalaninaemias	0.008	0.991	0.000
E70.0 Classical phenylketonuria	0.008	0.991	0.000
E71.3 Disorders of fatty-acid metabolism	0.008	0.991	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.008	0.991	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.008	0.991	0.000
E71.0 Maple-syrup-urine disease	0.008	0.991	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.008	0.991	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.008	0.991	0.000
E72.5 Disorders of glycine metabolism	0.008	0.991	0.000
E72.4 Disorders of ornithine metabolism	0.008	0.991	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.008	0.991	0.000
E72.2 Disorders of urea cycle metabolism	0.008	0.991	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.008	0.991	0.000
E72.0 Disorders of amino-acid transport	0.008	0.991	0.000
E75.6 Lipid storage disorder, unspecified	0.008	0.991	0.000
E75.5 Other lipid storage disorders	0.008	0.991	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.008	0.991	0.000
E75.3 Sphingolipidosis, unspecified	0.008	0.991	0.000
E75.2 Other sphingolipidosis	0.008	0.991	0.000
E75.1 Other gangliosidosis	0.008	0.991	0.000
E75.0 GM2 gangliosidosis	0.008	0.991	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.008	0.991	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.008	0.991	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.008	0.991	0.000
E76.2 Other mucopolysaccharidoses	0.008	0.991	0.000
E76.1 Mucopolysaccharidosis, type II	0.008	0.991	0.000
E76.0 Mucopolysaccharidosis, type I	0.008	0.991	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.008	0.991	0.000
E77.8 Other disorders of glycoprotein metabolism	0.008	0.991	0.000
E77.1 Defects in glycoprotein degradation	0.008	0.991	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.008	0.991	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.008	0.991	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.008	0.991	0.000
E79.1 Lesch-Nyhan syndrome	0.008	0.991	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.008	0.991	0.000
E84.9 Cystic fibrosis, unspecified	0.008	0.991	0.000
E84.8 Cystic fibrosis with other manifestations	0.008	0.991	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.008	0.991	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.008	0.991	0.000
E13.9 Without complications	0.008	0.991	0.000
S09.9 Unspecified injury of head	0.000	0.991	0.009
M51 Other intervertebral disk disorders	0.008	0.992	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.008	0.992	0.000
E21.4 Other specified disorders of parathyroid gland	0.008	0.992	0.000
E21.2 Other hyperparathyroidism	0.008	0.992	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.008	0.992	0.000
E07.8 Other specified disorders of thyroid	0.008	0.992	0.000
E07.1 Dyshormogenetic goitre	0.008	0.992	0.000
E07.0 Hypersecretion of calcitonin	0.008	0.992	0.000
E04 Other non-toxic goitre	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.008	0.992	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.008	0.992	0.000
E45 Retarded development following protein-energy malnutrition	0.008	0.992	0.000
E43 Unspecified severe protein-energy malnutrition	0.008	0.992	0.000
E42 Marasmic kwashiorkor	0.008	0.992	0.000
E41 Nutritional marasmus	0.008	0.992	0.000
E40 Kwashiorkor	0.008	0.992	0.000
E06.3 Autoimmune thyroiditis	0.008	0.992	0.000
E78.2 Mixed hyperlipidaemia	0.008	0.992	0.000
E22 Hyperfunction of pituitary gland	0.008	0.992	0.000
E20.9 Hypoparathyroidism, unspecified	0.008	0.992	0.000
I50 Heart failure	0.008	0.992	0.000
E14.3 With ophthalmic complications	0.008	0.992	0.000
I49.3 Ventricular premature depolarisation	0.008	0.992	0.000
I31 Other diseases of pericardium	0.008	0.992	0.000
E65-E68 Obesity and other hyperalimentation	0.008	0.992	0.000
E46 Unspecified protein-energy malnutrition	0.008	0.992	0.000
M50.1 Cervical disk disorder with radiculopathy	0.008	0.992	0.000
E14.8 With unspecified complications	0.008	0.992	0.000
E14.7 With multiple complications	0.008	0.992	0.000
E14.6 With other specified complications	0.008	0.992	0.000
E14.5 With peripheral circulatory complications	0.008	0.992	0.000
E14.4 With neurological complications	0.008	0.992	0.000
E14.2 Withrenal complications	0.008	0.992	0.000
E14.1 With ketoacidosis	0.008	0.992	0.000
E14.0 With coma	0.008	0.992	0.000
E06.9 Thyroiditis, unspecified	0.007	0.992	0.000
E29 Testicular dysfunction	0.007	0.992	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.007	0.993	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.007	0.993	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.007	0.993	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.007	0.993	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.007	0.993	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.007	0.993	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.007	0.993	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.007	0.993	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.007	0.993	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.007	0.993	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.007	0.993	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.007	0.993	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.007	0.993	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.007	0.993	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.007	0.993	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.007	0.993	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.007	0.993	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.007	0.993	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.007	0.993	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.007	0.993	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.007	0.993	0.000
M53.29 Spinal instabilities (Site unspecified)	0.007	0.993	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.007	0.993	0.000
M53.26 Spinal instabilities (Lumbar region)	0.007	0.993	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.007	0.993	0.000
M53.24 Spinal instabilities (Thoracic region)	0.007	0.993	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.007	0.993	0.000
M53.22 Spinal instabilities (Cervical region)	0.007	0.993	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.007	0.993	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.007	0.993	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.007	0.993	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.007	0.993	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.007	0.993	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.007	0.993	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.007	0.993	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.007	0.993	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.007	0.993	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.007	0.993	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.007	0.993	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.007	0.993	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.007	0.993	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.007	0.993	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.007	0.993	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.007	0.993	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.007	0.993	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.007	0.993	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.007	0.993	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.007	0.993	0.000
E28 Ovarian dysfunction	0.007	0.993	0.000
E06.5 Other chronic thyroiditis	0.007	0.993	0.000
E06.4 Drug-induced thyroiditis	0.007	0.993	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.007	0.993	0.000
E06.1 Subacute thyroiditis	0.007	0.993	0.000
E06.0 Acute thyroiditis	0.007	0.993	0.000
E20.8 Other hypoparathyroidism	0.007	0.993	0.000
E20.1 Pseudohypoparathyroidism	0.007	0.993	0.000
E20.0 Idiopathic hypoparathyroidism	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.000
E27.2 Addisonian crisis	0.007	0.993	0.000
M50.9 Cervical disk disorder, unspecified	0.007	0.993	0.000
M50.8 Other cervical disk disorders	0.007	0.993	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.007	0.993	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.007	0.993	0.000
E16.4 Abnormal secretion of gastrin	0.007	0.993	0.000
E16.3 Increased secretion of glucagon	0.007	0.993	0.000
E16.1 Other hypoglycaemia	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.007	0.993	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.007	0.993	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.007	0.993	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.007	0.993	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.007	0.993	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.007	0.993	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.007	0.993	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.007	0.993	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.007	0.993	0.000
I49 Other cardiac arrhythmias	0.007	0.993	0.000
E27.5 Adrenomedullary hyperfunction	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
E27.0 Other adrenocortical overactivity	0.007	0.993	0.000
M51.9 Intervertebral disk disorder, unspecified	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
E04.1 Non-toxic single thyroid nodule	0.007	0.993	0.000
I30-I52 Other forms of heart disease	0.007	0.993	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.006	0.993	0.000
E24.8 Other Cushing's syndrome	0.006	0.993	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.993	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.993	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.993	0.000
E24.1 Nelson's syndrome	0.006	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.006	0.993	0.000
E25.8 Other adrenogenital disorders	0.006	0.993	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.006	0.993	0.000
E30.9 Disorder of puberty, unspecified	0.006	0.993	0.000
E30.8 Other disorders of puberty	0.006	0.993	0.000
E30.1 Precocious puberty	0.006	0.993	0.000
E30.0 Delayed puberty	0.006	0.993	0.000
E31.9 Polyglandular dysfunction, unspecified	0.006	0.993	0.000
E31.8 Other polyglandular dysfunction	0.006	0.993	0.000
E31.1 Polyglandular hyperfunction	0.006	0.993	0.000
E31.0 Autoimmune polyglandular failure	0.006	0.993	0.000
E32.9 Disease of thymus, unspecified	0.006	0.993	0.000
E32.8 Other diseases of thymus	0.006	0.993	0.000
E32.1 Abscess of thymus	0.006	0.993	0.000
E32.0 Persistent hyperplasia of thymus	0.006	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.006	0.993	0.000
E34.8 Other specified endocrine disorders	0.006	0.993	0.000
E34.5 Androgen resistance syndrome	0.006	0.993	0.000
E34.4 Constitutional tall stature	0.006	0.993	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.993	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.006	0.993	0.000
E34.1 Other hypersecretion of intestinal hormones	0.006	0.993	0.000
E34.0 Carcinoid syndrome	0.006	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.006	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.006	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.006	0.993	0.000
I49.4 Other and unspecified premature depolarisation	0.007	0.993	0.000
E26.9 Hyperaldosteronism, unspecified	0.006	0.993	0.000
E26.8 Other hyperaldosteronism	0.006	0.993	0.000
E26.1 Secondary hyperaldosteronism	0.006	0.993	0.000
J84 Other interstitial pulmonary diseases	0.000	0.993	0.007
E23.0 Hypopituitarism	0.006	0.993	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.006	0.993	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.006	0.993	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.006	0.993	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.006	0.993	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.006	0.993	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.006	0.993	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.006	0.993	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.006	0.993	0.000
E16.2 Hypoglycaemia, unspecified	0.007	0.993	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.007	0.993	0.000
E03 Other hypothyroidism	0.007	0.993	0.000
E26.0 Primary hyperaldosteronism	0.006	0.993	0.000
E04.0 Non-toxic diffuse goitre	0.006	0.993	0.000
E04.9 Non-toxic goitre, unspecified	0.006	0.994	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.006	0.994	0.000
I31.9 Disease of pericardium, unspecified	0.006	0.994	0.000
M50.2 Other cervical disk displacement	0.006	0.994	0.000
M51.3 Other specified intervertebral disk degeneration	0.006	0.994	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.006	0.994	0.000
M51.4 Schmorl's nodes	0.006	0.994	0.000
E04.8 Other specified non-toxic goitre	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.006	0.994	0.000
E51 Thiamine deficiency	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations