TreeWAS – Variant ID: rs12409277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.001	0.999
I20 Angina pectoris	0.000	0.001	0.999
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.004	0.996
I20.0 Unstable angina	0.000	0.004	0.996
I25.2 Old myocardial infarction	0.000	0.010	0.990
I20.8 Other forms of angina pectoris	0.000	0.044	0.956
I21 Acute myocardial infarction	0.000	0.095	0.905
I25.1 Atherosclerotic heart disease	0.000	0.104	0.896
I21.9 Acute myocardial infarction, unspecified	0.000	0.114	0.886
I25.5 Ischaemic cardiomyopathy	0.000	0.183	0.817
I20.9 Angina pectoris, unspecified	0.000	0.195	0.805
I22 Subsequent myocardial infarction	0.000	0.216	0.784
I20.1 Angina pectoris with documented spasm	0.000	0.216	0.784
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.241	0.759
I25.4 Coronary artery aneurysm	0.000	0.264	0.736
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.325	0.674
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.351	0.649
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.374	0.626
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.382	0.618
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.383	0.616
I22.8 Subsequent myocardial infarction of other sites	0.000	0.395	0.605
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.407	0.593
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.422	0.578
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.565	0.435	0.000
M18 Arthrosis of first carpometacarpal joint	0.561	0.439	0.000
I25.3 Aneurysm of heart	0.000	0.457	0.543
M18.1 Other primary arthrosis of first carpometacarpal joint	0.535	0.465	0.000
M54 Dorsalgia	0.535	0.465	0.000
M50-M54 Other dorsopathies	0.531	0.469	0.000
M15-M19 Arthrosis	0.529	0.471	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.529	0.471	0.000
M54.4 Lumbago with sciatica	0.520	0.480	0.000
M45-M49 Spondylopathies	0.517	0.483	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.485	0.515
M54.3 Sciatica	0.511	0.489	0.000
M48 Other spondylopathies	0.503	0.497	0.000
M54.39 Sciatica (Site unspecified)	0.496	0.504	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.508	0.492
M54.46 Lumbago with sciatica (Lumbar region)	0.484	0.516	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.516	0.484
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.516	0.484
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.516	0.484
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.516	0.484
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.516	0.484
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.516	0.484
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.516	0.484
M48.0 Spinal stenosis	0.482	0.518	0.000
M00-M03 Infectious arthropathies	0.481	0.518	0.000
M80-M85 Disorders of bone density and structure	0.479	0.521	0.000
M54.8 Other dorsalgia	0.460	0.540	0.000
M47 Spondylosis	0.458	0.542	0.000
M54.6 Pain in thoracic spine	0.456	0.544	0.000
M48.02 Spinal stenosis (Cervical region)	0.445	0.555	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.558	0.442
M54.47 Lumbago with sciatica (Lumbosacral region)	0.440	0.560	0.000
M60-M63 Disorders of muscles	0.439	0.561	0.000
M00 Pyogenic arthritis	0.436	0.564	0.000
M19 Other arthrosis	0.436	0.564	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.436	0.564	0.000
M53 Other dorsopathies, not elsewhere classified	0.432	0.568	0.000
M91-M94 Chondropathies	0.431	0.569	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.426	0.574	0.000
M48.8 Other specified spondylopathies	0.419	0.581	0.000
M47.2 Other spondylosis with radiculopathy	0.418	0.582	0.000
M54.36 Sciatica (Lumbar region)	0.418	0.582	0.000
M54.5 Low back pain	0.418	0.582	0.000
M54.1 Radiculopathy	0.417	0.583	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.415	0.585	0.000
M85 Other disorders of bone density and structure	0.406	0.594	0.000
M84 Disorders of continuity of bone	0.405	0.595	0.000
M00.9 Pyogenic arthritis, unspecified	0.404	0.596	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.402	0.598	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.402	0.598	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.402	0.598	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.402	0.598	0.000
M48.06 Spinal stenosis (Lumbar region)	0.401	0.599	0.000
M48.09 Spinal stenosis (Site unspecified)	0.401	0.599	0.000
M50 Cervical disk disorders	0.400	0.600	0.000
M49 Spondylopathies in diseases classified elsewhere	0.399	0.601	0.000
M60 Myositis	0.391	0.609	0.000
M15 Polyarthrosis	0.391	0.609	0.000
M54.57 Low back pain (Lumbosacral region)	0.391	0.609	0.000
M19.0 Primary arthrosis of other joints	0.387	0.613	0.000
M81 Osteoporosis without pathological fracture	0.384	0.615	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.384	0.616	0.000
M54.0 Panniculitis affecting regions of neck and back	0.383	0.616	0.000
M54.86 Other dorsalgia (Lumbar region)	0.380	0.620	0.000
M02 Reactive arthropathies	0.379	0.620	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.379	0.621	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.374	0.626	0.000
M83 Adult osteomalacia	0.373	0.627	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.373	0.627	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.373	0.627	0.000
M54.44 Lumbago with sciatica-Thoracic	0.373	0.627	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.373	0.627	0.000
M54.42 Lumbago with sciatica-Cervical	0.373	0.627	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.373	0.627	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.373	0.627	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.373	0.627	0.000
M47.8 Other spondylosis	0.372	0.628	0.000
M54.12 Radiculopathy (Cervical region)	0.370	0.630	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.367	0.633	0.000
M54.35 Sciatica (Thoracolumbar region)	0.366	0.634	0.000
M54.34 Sciatica-Thoracic	0.366	0.634	0.000
M54.33 Sciatica-Cervicothoracic	0.366	0.634	0.000
M54.32 Sciatica-Cervical	0.366	0.634	0.000
M54.31 Sciatica-Occipit-atl-axl	0.366	0.634	0.000
M54.30 Sciatica (Multiple sites in spine)	0.366	0.634	0.000
M47.1 Other spondylosis with myelopathy	0.366	0.634	0.000
M94 Other disorders of cartilage	0.363	0.636	0.000
M48.9 Spondylopathy, unspecified	0.361	0.639	0.000
M48.4 Fatigue fracture of vertebra	0.361	0.639	0.000
M48.3 Traumatic spondylopathy	0.361	0.639	0.000
M48.2 Kissing spine	0.361	0.639	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.361	0.639	0.000
M19.1 Posttraumatic arthrosis of other joints	0.360	0.640	0.000
M54.84 Other dorsalgia (Thoracic region)	0.358	0.642	0.000
M47.89 Other spondylosis (Site unspecified)	0.356	0.644	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.355	0.644	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.354	0.646	0.000
M50.2 Other cervical disk displacement	0.353	0.647	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.352	0.648	0.000
M54.89 Other dorsalgia (Site unspecified)	0.351	0.649	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.348	0.652	0.000
M19.2 Other secondary arthrosis	0.347	0.653	0.000
M85.6 Other cyst of bone	0.347	0.653	0.000
M81.9 Osteoporosis, unspecified	0.347	0.653	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.346	0.654	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.346	0.654	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.346	0.654	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.346	0.654	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.345	0.655	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.345	0.655	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.341	0.659	0.000
M53.9 Dorsopathy, unspecified	0.340	0.659	0.000
M54.16 Radiculopathy (Lumbar region)	0.340	0.660	0.000
M84.4 Pathological fracture, not elsewhere classified	0.339	0.661	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.338	0.662	0.000
M94.8 Other specified disorders of cartilage	0.337	0.663	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.336	0.664	0.000
M47.86 Other spondylosis (Lumbar region)	0.333	0.667	0.000
M53.2 Spinal instabilities	0.332	0.668	0.000
M60.9 Myositis, unspecified	0.332	0.668	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.331	0.669	0.000
I24 Other acute ischaemic heart diseases	0.000	0.669	0.331
M86-M90 Other osteopathies	0.330	0.669	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.330	0.670	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.330	0.670	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.330	0.670	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.330	0.670	0.000
M54.82 Other dorsalgia (Cervical region)	0.330	0.670	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.330	0.670	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.330	0.670	0.000
M84.0 Malunion of fracture	0.329	0.671	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.328	0.672	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.328	0.672	0.000
M60.0 Infective myositis	0.328	0.672	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.328	0.672	0.000
M54.69 Pain in thoracic spine-Site unspe	0.327	0.673	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.327	0.673	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.327	0.673	0.000
M54.66 Pain in thoracic spine-Lumbar	0.327	0.673	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.327	0.673	0.000
M54.62 Pain in thoracic spine-Cervical	0.327	0.673	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.327	0.673	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.327	0.673	0.000
M19.8 Other specified arthrosis	0.327	0.673	0.000
M82 Osteoporosis in diseases classified elsewhere	0.326	0.674	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.326	0.674	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.326	0.674	0.000
M51 Other intervertebral disk disorders	0.326	0.674	0.000
M93 Other osteochondropathies	0.324	0.676	0.000
M46 Other inflammatory spondylopathies	0.322	0.678	0.000
M50.0 Cervical disk disorder with myelopathy	0.321	0.679	0.000
M45 Ankylosing spondylitis	0.318	0.681	0.000
M54.55 Low back pain (Thoracolumbar region)	0.318	0.682	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.316	0.684	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.315	0.685	0.000
M61 Calcification and ossification of muscle	0.315	0.685	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.314	0.686	0.000
M53.8 Other specified dorsopathies	0.313	0.687	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.313	0.687	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.313	0.687	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.313	0.687	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.313	0.687	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.313	0.687	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.312	0.688	0.000
M85.4 Solitary bone cyst	0.311	0.689	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.311	0.689	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.311	0.689	0.000
M53.1 Cervicobrachial syndrome	0.310	0.690	0.000
M53.0 Cervicocranial syndrome	0.310	0.690	0.000
M54.37 Sciatica (Lumbosacral region)	0.306	0.694	0.000
M54.14 Radiculopathy (Thoracic region)	0.306	0.694	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.305	0.695	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.305	0.695	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.304	0.695	0.000
M19.08 Primary arthrosis of other joints (Other)	0.304	0.696	0.000
M84.3 Stress fracture, not elsewhere classified	0.303	0.697	0.000
M84.8 Other disorders of continuity of bone	0.303	0.697	0.000
M85.0 Fibrous dysplasia (monostotic)	0.303	0.697	0.000
M85.9 Disorder of bone density and structure, unspecified	0.302	0.698	0.000
M02.9 Reactive arthopathy, unspecified	0.300	0.700	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.300	0.700	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.300	0.700	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.300	0.700	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.300	0.700	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.300	0.700	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.300	0.700	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.300	0.700	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.300	0.700	0.000
M54.56 Low back pain (Lumbar region)	0.300	0.700	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.300	0.700	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.300	0.700	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.300	0.700	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.300	0.700	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.300	0.700	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.300	0.700	0.000
M54.54 Low back pain-Thoracic	0.299	0.700	0.000
M54.53 Low back pain-Cervicothoracic	0.299	0.700	0.000
M54.52 Low back pain-Cervical	0.299	0.700	0.000
M54.51 Low back pain-Occipit-atl-axl	0.299	0.700	0.000
M48.04 Spinal stenosis (Thoracic region)	0.299	0.700	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.299	0.701	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.299	0.701	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.299	0.701	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.299	0.701	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.298	0.701	0.000
M15.1 Heberden's nodes (with arthropathy)	0.298	0.702	0.000
M83.8 Other adult osteomalacia	0.297	0.703	0.000
M85.64 Other cyst of bone (Hand)	0.297	0.703	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.296	0.703	0.000
M92 Other juvenile osteochondrosis	0.295	0.704	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.295	0.705	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.295	0.705	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.295	0.705	0.000
M85.5 Aneurysmal bone cyst	0.291	0.709	0.000
M85.3 Osteitis condensans	0.291	0.709	0.000
M85.2 Hyperostosis of skull	0.291	0.709	0.000
M85.1 Skeletal fluorosis	0.291	0.709	0.000
M15.8 Other polyarthrosis	0.291	0.709	0.000
M84.9 Disorder of continuity of bone, unspecified	0.290	0.710	0.000
M84.2 Delayed union of fracture	0.290	0.710	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.290	0.710	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.290	0.710	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.290	0.710	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.290	0.710	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.290	0.710	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.289	0.711	0.000
M99 Biomechanical lesions, not elsewhere classified	0.288	0.711	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.288	0.712	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.287	0.713	0.000
M50.8 Other cervical disk disorders	0.287	0.713	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.286	0.714	0.000
M49.4 Neuropathic spondylopathy	0.286	0.714	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.286	0.714	0.000
M49.2 Enterobacterial spondylitis	0.286	0.714	0.000
M49.1 Brucella spondylitis	0.286	0.714	0.000
M49.0 Tuberculosis of spine	0.286	0.714	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.286	0.714	0.000
M40-M43 Deforming dorsopathies	0.284	0.716	0.000
M50.9 Cervical disk disorder, unspecified	0.283	0.717	0.000
M80 Osteoporosis with pathological fracture	0.282	0.718	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.281	0.719	0.000
M60.8 Other myositis	0.281	0.719	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.281	0.719	0.000
M60.1 Interstitial myositis	0.281	0.719	0.000
M15.9 Polyarthrosis, unspecified	0.281	0.719	0.000
M15.0 Primary generalised (osteo)arthrosis	0.281	0.719	0.000
M15.4 Erosive (osteo)arthrosis	0.281	0.719	0.000
M15.3 Secondary multiple arthrosis	0.281	0.719	0.000
M02.3 Reiter's disease	0.280	0.720	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.278	0.722	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.277	0.722	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.277	0.723	0.000
M51.8 Other specified intervertebral disk disorders	0.276	0.724	0.000
M81.8 Other osteoporosis	0.276	0.724	0.000
M81.6 Localised osteoporosis [Lequesne]	0.276	0.724	0.000
M81.5 Idiopathic osteoporosis	0.276	0.724	0.000
M81.1 Postoophorectomy osteoporosis	0.276	0.724	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.275	0.725	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.275	0.725	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.275	0.725	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.275	0.725	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.275	0.725	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.275	0.725	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.275	0.725	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.275	0.725	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.275	0.725	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.275	0.725	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.275	0.725	0.000
M86 Osteomyelitis	0.275	0.725	0.000
M62 Other disorders of muscle	0.273	0.727	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.273	0.727	0.000
M02.8 Other reactive arthropathies	0.272	0.728	0.000
M02.2 Postimmunisation arthropathy	0.272	0.728	0.000
M02.1 Postdysenteric arthropathy	0.272	0.728	0.000
M02.0 Arthropathy following intestinal bypass	0.272	0.728	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.272	0.728	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.272	0.728	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.272	0.728	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.272	0.728	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.272	0.728	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.272	0.728	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.272	0.728	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.272	0.728	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.271	0.729	0.000
M54.19 Radiculopathy (Site unspecified)	0.270	0.730	0.000
M50.1 Cervical disk disorder with radiculopathy	0.269	0.731	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.269	0.731	0.000
M83.9 Adult osteomalacia, unspecified	0.268	0.732	0.000
M83.5 Other drug-induced osteomalacia in adults	0.268	0.732	0.000
M83.4 Aluminum bone disease	0.268	0.732	0.000
M83.3 Adult osteomalacia due to malnutrition	0.268	0.732	0.000
M83.2 Adult osteomalacia due to malabsorption	0.268	0.732	0.000
M83.1 Senile osteomalacia	0.268	0.732	0.000
M83.0 Puerperal osteomalacia	0.268	0.732	0.000
M81.2 Osteoporosis of disuse	0.267	0.732	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.267	0.733	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.267	0.733	0.000
M81.0 Postmenopausal osteoporosis	0.266	0.734	0.000
M84.04 Malunion of fracture (Hand)	0.265	0.735	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.265	0.735	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.264	0.736	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.262	0.737	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.262	0.737	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.262	0.737	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.262	0.737	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.262	0.737	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.262	0.737	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.262	0.737	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.262	0.737	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.261	0.739	0.000
M94.88 Other specified disorders of cartilage (Other)	0.261	0.739	0.000
M94.3 Chondrolysis	0.261	0.739	0.000
M94.1 Relapsing polychondritis	0.261	0.739	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.261	0.739	0.000
M53.26 Spinal instabilities (Lumbar region)	0.260	0.740	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.260	0.740	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.259	0.740	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.259	0.741	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.259	0.741	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.259	0.741	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.259	0.741	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.259	0.741	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.259	0.741	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.259	0.741	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.259	0.741	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.259	0.741	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.259	0.741	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.259	0.741	0.000
M48.29 Kissing spine (Site unspecified)	0.259	0.741	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.259	0.741	0.000
M48.27 Kissing spine (Lumbosacral region)	0.259	0.741	0.000
M48.26 Kissing spine (Lumbar region)	0.259	0.741	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.259	0.741	0.000
M48.24 Kissing spine (Thoracic region)	0.259	0.741	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.259	0.741	0.000
M48.22 Kissing spine (Cervical region)	0.259	0.741	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.259	0.741	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.259	0.741	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.259	0.741	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.259	0.741	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.259	0.741	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.259	0.741	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.259	0.741	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.259	0.741	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.259	0.741	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.259	0.741	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.259	0.741	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.259	0.741	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.259	0.741	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.259	0.741	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.259	0.741	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.259	0.741	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.259	0.741	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.259	0.741	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.259	0.741	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.259	0.741	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.259	0.741	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.259	0.741	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.259	0.741	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.259	0.741	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.259	0.741	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.259	0.741	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.259	0.741	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.259	0.741	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.259	0.741	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.259	0.741	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.259	0.741	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.259	0.741	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.258	0.741	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.258	0.741	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.258	0.741	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.258	0.741	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.258	0.741	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.258	0.741	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.254	0.745	0.000
M65-M68 Disorders of synovium and tendon	0.254	0.746	0.000
M60.08 Infective myositis (Other)	0.253	0.747	0.000
M85.8 Other specified disorders of bone density and structure	0.253	0.747	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.252	0.748	0.000
M54.2 Cervicalgia	0.251	0.748	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.251	0.749	0.000
M94.2 Chondromalacia	0.250	0.750	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.249	0.751	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.249	0.751	0.000
M19.28 Other secondary arthrosis (Other)	0.249	0.751	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.249	0.751	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.249	0.751	0.000
M19.24 Other secondary arthrosis (Hand)	0.249	0.751	0.000
M19.23 Other secondary arthrosis (Forearm)	0.249	0.751	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.249	0.751	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.249	0.751	0.000
M85.69 Other cyst of bone (Site unspecified)	0.249	0.751	0.000
M85.68 Other cyst of bone (Other)	0.249	0.751	0.000
M85.66 Other cyst of bone (Lower leg)	0.249	0.751	0.000
M85.63 Other cyst of bone (Forearm)	0.249	0.751	0.000
M85.62 Other cyst of bone (Upper arm)	0.249	0.751	0.000
M85.61 Other cyst of bone (Shoulder region)	0.249	0.751	0.000
M85.60 Other cyst of bone (Multiple sites)	0.249	0.751	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.249	0.751	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.249	0.751	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.249	0.751	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.249	0.751	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.248	0.751	0.000
M90 Osteopathies in diseases classified elsewhere	0.248	0.751	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.248	0.751	0.000
M51.9 Intervertebral disk disorder, unspecified	0.248	0.752	0.000
M93.9 Osteochondropathy, unspecified	0.248	0.752	0.000
M01.8 Arthritis in other infectious and parasitic diseases classified elsewhere	0.248	0.752	0.000
M01.6 Arthritis in mycoses	0.248	0.752	0.000
M01.5 Arthritis in other viral diseases classified elsewhere	0.248	0.752	0.000
M01.4 Rubella arthritis	0.248	0.752	0.000
M01.3 Arthritis in other bacterial diseases classified elsewhere	0.248	0.752	0.000
M01.2 Arthritis in Lyme disease	0.248	0.752	0.000
M01.1 Tuberculous arthritis	0.248	0.752	0.000
M01.0 Meningococcal arthritis	0.248	0.752	0.000
M03.6 Reactive arthropathy in other diseases classified elsewhere	0.248	0.752	0.000
M03.2 Other postinfectious arthropathies in diseases classified elsewhere	0.248	0.752	0.000
M03.1 Postinfective arthropathy in syphilis	0.248	0.752	0.000
M03.0 Postmeningococcal arthritis	0.248	0.752	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.247	0.752	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.247	0.753	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.246	0.754	0.000
M46.2 Osteomyelitis of vertebra	0.244	0.756	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.244	0.756	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.244	0.756	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.244	0.756	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.244	0.756	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.244	0.756	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.244	0.756	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.244	0.756	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.244	0.756	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.244	0.756	0.000
M02.90 Reactive arthropathy, unspecified (Multiple sites)	0.244	0.756	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.243	0.757	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.243	0.757	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.243	0.757	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.243	0.757	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.243	0.757	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.243	0.757	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.243	0.757	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.243	0.757	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.243	0.757	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.243	0.757	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.243	0.757	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.243	0.757	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.242	0.758	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.242	0.758	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.242	0.758	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.242	0.758	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.242	0.758	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.242	0.758	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.242	0.758	0.000
M84.01 Malunion of fracture (Shoulder region)	0.241	0.759	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.239	0.761	0.000
M46.0 Spinal enthesopathy	0.239	0.761	0.000
M81.98 Osteoporosis, unspecified (Other)	0.238	0.762	0.000
M53.29 Spinal instabilities (Site unspecified)	0.238	0.762	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.238	0.762	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.238	0.762	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.238	0.762	0.000
M53.24 Spinal instabilities (Thoracic region)	0.238	0.762	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.238	0.762	0.000
M53.22 Spinal instabilities (Cervical region)	0.238	0.762	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.238	0.762	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.238	0.762	0.000
M60.98 Myositis, unspecified (Other)	0.238	0.762	0.000
M60.97 Myositis, unspecified (Ankle and foot)	0.238	0.762	0.000
M60.96 Myositis, unspecified (Lower leg)	0.238	0.762	0.000
M60.94 Myositis, unspecified (Hand)	0.238	0.762	0.000
M60.93 Myositis, unspecified (Forearm)	0.238	0.762	0.000
M60.92 Myositis, unspecified (Upper arm)	0.238	0.762	0.000
M60.91 Myositis, unspecified (Shoulder region)	0.238	0.762	0.000
M60.90 Myositis, unspecified (Multiple sites)	0.238	0.762	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.236	0.764	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations