TreeWAS – Variant ID: rs12428086

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.0 Calculus of gallbladder with acute cholecystitis	0.744	0.256	0.000
K80 Cholelithiasis	0.670	0.330	0.000
K86 Other diseases of pancreas	0.667	0.333	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.663	0.337	0.000
K86.1 Other chronic pancreatitis	0.646	0.354	0.000
K81 Cholecystitis	0.616	0.384	0.000
K86.3 Pseudocyst of pancreas	0.610	0.390	0.000
K86.2 Cyst of pancreas	0.608	0.392	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.598	0.402	0.000
K81.9 Cholecystitis, unspecified	0.582	0.418	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.574	0.426	0.000
K81.0 Acute cholecystitis	0.556	0.444	0.000
K83 Other diseases of biliary tract	0.536	0.464	0.000
K80.3 Calculus of bile duct with cholangitis	0.480	0.520	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.475	0.525	0.000
K83.4 Spasm of sphincter of Oddi	0.446	0.554	0.000
K80.4 Calculus of bile duct with cholecystitis	0.442	0.558	0.000
K86.9 Disease of pancreas, unspecified	0.440	0.560	0.000
K83.0 Cholangitis	0.424	0.576	0.000
K83.2 Perforation of bile duct	0.424	0.576	0.000
K83.3 Fistula of bile duct	0.418	0.581	0.000
K83.5 Biliary cyst	0.401	0.599	0.000
K83.9 Disease of biliary tract, unspecified	0.368	0.632	0.000
K86.8 Other specified diseases of pancreas	0.358	0.642	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.344	0.655	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.341	0.659	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.341	0.659	0.000
K83.1 Obstruction of bile duct	0.337	0.663	0.000
K81.1 Chronic cholecystitis	0.321	0.679	0.000
K81.8 Other cholecystitis	0.319	0.680	0.000
K80.8 Other cholelithiasis	0.316	0.684	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.308	0.692	0.000
K85 Acute pancreatitis	0.296	0.704	0.000
K83.8 Other specified diseases of biliary tract	0.250	0.750	0.000
K85.3 Drug-induced acute pancreatitis	0.226	0.774	0.000
K85.0 Idiopathic acute pancreatitis	0.216	0.784	0.000
K85.8 Other acute pancreatitis	0.211	0.789	0.000
K82 Other diseases of gallbladder	0.186	0.814	0.000
K85.1 Biliary acute pancreatitis	0.182	0.818	0.000
K85.2 Alcohol-induced acute pancreatitis	0.165	0.835	0.000
K82.0 Obstruction of gallbladder	0.142	0.858	0.000
K85.9 Acute pancreatitis, unspecified	0.142	0.858	0.000
K82.1 Hydrops of gallbladder	0.137	0.863	0.000
K82.2 Perforation of gallbladder	0.132	0.868	0.000
K82.9 Disease of gallbladder, unspecified	0.121	0.879	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.113	0.887	0.000
K82.3 Fistula of gallbladder	0.110	0.890	0.000
K82.8 Other specified diseases of gallbladder	0.094	0.906	0.000
K82.4 Cholesterolosis of gallbladder	0.051	0.949	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.023	0.977	0.000
M70.6 Trochanteric bursitis	0.015	0.985	0.000
M70.69 Trochanteric bursitis-Site unspec	0.011	0.989	0.000
M70.68 Trochanteric bursitis-Other	0.011	0.989	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.011	0.989	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.011	0.989	0.000
M70.64 Trochanteric bursitis-Hand	0.011	0.989	0.000
M70.63 Trochanteric bursitis-Forearm	0.011	0.989	0.000
M70.62 Trochanteric bursitis-Upper arm	0.011	0.989	0.000
M70.61 Trochanteric bursitis-Shldr region	0.011	0.989	0.000
M70.60 Trochanteric bursitis-Mult sites	0.011	0.989	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.009	0.991	0.000
M70.4 Prepatellar bursitis	0.008	0.991	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.008	0.992	0.000
M84.03 Malunion of fracture (Forearm)	0.008	0.992	0.000
M70.3 Other bursitis of elbow	0.007	0.993	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.007	0.993	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.007	0.993	0.000
M70.1 Bursitis of hand	0.007	0.993	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.007	0.993	0.000
M70.2 Olecranon bursitis	0.006	0.994	0.000
M70.49 Prepatellar bursitis-Site unspec	0.006	0.994	0.000
M70.48 Prepatellar bursitis-Other	0.006	0.994	0.000
M70.47 Prepatellar bursitis-Ankle/Foot	0.006	0.994	0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.006	0.994	0.000
M70.44 Prepatellar bursitis-Hand	0.006	0.994	0.000
M70.43 Prepatellar bursitis-Forearm	0.006	0.994	0.000
M70.42 Prepatellar bursitis-Upper arm	0.006	0.994	0.000
M70.41 Prepatellar bursitis-Shldr region	0.006	0.994	0.000
M70.40 Prepatellar bursitis-Mult sites	0.006	0.994	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.006	0.994	0.000
M70.7 Other bursitis of hip	0.006	0.994	0.000
M70.5 Other bursitis of knee	0.006	0.994	0.000
Z83.7 Family history of diseases of the digestive system	0.005	0.995	0.000
M70.32 Other bursitis of elbow-Upper arm	0.005	0.995	0.000
M70.39 Other bursitis of elbow-Site unspec	0.005	0.995	0.000
M70.38 Other bursitis of elbow-Other	0.005	0.995	0.000
M70.37 Other bursitis of elbow-Ankle/Foot	0.005	0.995	0.000
M70.36 Other bursitis of elbow-Lower Leg	0.005	0.995	0.000
M70.35 Other bursitis of elbow-Pelvic/Thigh	0.005	0.995	0.000
M70.34 Other bursitis of elbow-Hand	0.005	0.995	0.000
M70.33 Other bursitis of elbow-Forearm	0.005	0.995	0.000
M70.31 Other bursitis of elbow-Shldr region	0.005	0.995	0.000
M70.30 Other bursitis of elbow-Mult sites	0.005	0.995	0.000
M70.09 Chronic crepitant synovitis of hand and wrist-Site unspec	0.005	0.995	0.000
M70.08 Chronic crepitant synovitis of hand and wrist-Other	0.005	0.995	0.000
M70.07 Chronic crepitant synovitis of hand and wrist-Ankle/Foot	0.005	0.995	0.000
M70.06 Chronic crepitant synovitis of hand and wrist-Lower Leg	0.005	0.995	0.000
M70.05 Chronic crepitant synovitis of hand and wrist-Pelvic/Thigh	0.005	0.995	0.000
M70.04 Chronic crepitant synovitis of hand and wrist (Hand)	0.005	0.995	0.000
M70.03 Chronic crepitant synovitis of hand and wrist (Forearm)	0.005	0.995	0.000
M70.02 Chronic crepitant synovitis of hand and wrist-Upper arm	0.005	0.995	0.000
M70.01 Chronic crepitant synovitis of hand and wrist-Shldr region	0.005	0.995	0.000
M70.00 Chronic crepitant synovitis of hand and wrist (Multiple sites)	0.005	0.995	0.000
M70.19 Bursitis of hand-Site unspec	0.005	0.995	0.000
M70.18 Bursitis of hand-Other	0.005	0.995	0.000
M70.17 Bursitis of hand-Ankle/Foot	0.005	0.995	0.000
M70.16 Bursitis of hand-Lower Leg	0.005	0.995	0.000
M70.15 Bursitis of hand-Pelvic/Thigh	0.005	0.995	0.000
M70.14 Bursitis of hand-Hand	0.005	0.995	0.000
M70.13 Bursitis of hand-Forearm	0.005	0.995	0.000
M70.12 Bursitis of hand-Upper arm	0.005	0.995	0.000
M70.11 Bursitis of hand-Shldr region	0.005	0.995	0.000
M70.10 Bursitis of hand-Mult sites	0.005	0.995	0.000
M70.89 Other soft tissue disorders related to use, overuse and pressure (Site unspecified)	0.005	0.995	0.000
M70.88 Other soft tissue disorders related to use, overuse and pressure (Other)	0.005	0.995	0.000
M70.87 Other soft tissue disorders related to use, overuse and pressure (Ankle and foot)	0.005	0.995	0.000
M70.86 Other soft tissue disorders related to use, overuse and pressure (Lower leg)	0.005	0.995	0.000
M70.85 Other soft tissue disorders related to use, overuse and pressure (Pelvic region and thigh)	0.005	0.995	0.000
M70.84 Other soft tissue disorders related to use, overuse and pressure (Hand)	0.005	0.995	0.000
M70.83 Other soft tissue disorders related to use, overuse and pressure (Forearm)	0.005	0.995	0.000
M70.82 Other soft tissue disorders related to use, overuse and pressure (Upper arm)	0.005	0.995	0.000
M70.81 Other soft tissue disorders related to use, overuse and pressure (Shoulder region)	0.005	0.995	0.000
M70.80 Other soft tissue disorders related to use, overuse and pressure (Multiple sites)	0.005	0.995	0.000
M70.99 Unspecified soft tissue disorder related to use, overuse and pressure (Site unspecified)	0.005	0.995	0.000
M70.98 Unspecified soft tissue disorder related to use, overuse and pressure (Other)	0.005	0.995	0.000
M70.97 Unspecified soft tissue disorder related to use, overuse and pressure (Ankle and foot)	0.005	0.995	0.000
M70.96 Unspecified soft tissue disorder related to use, overuse and pressure (Lower leg)	0.005	0.995	0.000
M70.95 Unspecified soft tissue disorder related to use, overuse and pressure (Pelvic region and thigh)	0.005	0.995	0.000
M70.94 Unspecified soft tissue disorder related to use, overuse and pressure (Hand)	0.005	0.995	0.000
M70.93 Unspecified soft tissue disorder related to use, overuse and pressure (Forearm)	0.005	0.995	0.000
M70.92 Unspecified soft tissue disorder related to use, overuse and pressure (Upper arm)	0.005	0.995	0.000
M70.91 Unspecified soft tissue disorder related to use, overuse and pressure (Shoulder region)	0.005	0.995	0.000
M70.90 Unspecified soft tissue disorder related to use, overuse and pressure (Multiple sites)	0.005	0.995	0.000
M84.0 Malunion of fracture	0.005	0.995	0.000
M70.29 Olecranon bursitis-Site unspec	0.005	0.995	0.000
M70.28 Olecranon bursitis-Other	0.005	0.995	0.000
M70.27 Olecranon bursitis-Ankle/Foot	0.005	0.995	0.000
M70.26 Olecranon bursitis-Lower Leg	0.005	0.995	0.000
M70.25 Olecranon bursitis-Pelvic/Thigh	0.005	0.995	0.000
M70.24 Olecranon bursitis-Hand	0.005	0.995	0.000
M70.23 Olecranon bursitis-Forearm	0.005	0.995	0.000
M70.21 Olecranon bursitis-Shldr region	0.005	0.995	0.000
M70.20 Olecranon bursitis-Mult sites	0.005	0.995	0.000
M70.79 Other bursitis of hip-Site unspec	0.004	0.995	0.000
M70.78 Other bursitis of hip-Other	0.004	0.995	0.000
M70.77 Other bursitis of hip-Ankle/Foot	0.004	0.995	0.000
M70.76 Other bursitis of hip-Lower Leg	0.004	0.995	0.000
M70.74 Other bursitis of hip-Hand	0.004	0.995	0.000
M70.73 Other bursitis of hip-Forearm	0.004	0.995	0.000
M70.72 Other bursitis of hip-Upper arm	0.004	0.995	0.000
M70.71 Other bursitis of hip-Shldr region	0.004	0.995	0.000
M70.70 Other bursitis of hip-Mult sites	0.004	0.995	0.000
M70.22 Olecranon bursitis-Upper arm	0.005	0.995	0.000
M70.59 Other bursitis of knee-Site unspec	0.004	0.995	0.000
M70.58 Other bursitis of knee-Other	0.004	0.995	0.000
M70.57 Other bursitis of knee-Ankle/Foot	0.004	0.995	0.000
M70.55 Other bursitis of knee-Pelvic/Thigh	0.004	0.995	0.000
M70.54 Other bursitis of knee-Hand	0.004	0.995	0.000
M70.53 Other bursitis of knee-Forearm	0.004	0.995	0.000
M70.52 Other bursitis of knee-Upper arm	0.004	0.995	0.000
M70.51 Other bursitis of knee-Shldr region	0.004	0.995	0.000
M70.50 Other bursitis of knee-Mult sites	0.004	0.995	0.000
L73.9 Follicular disorder, unspecified	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.996	0.004
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.996	0.004
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
Y43 Primarily systemic agents	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
M84.01 Malunion of fracture (Shoulder region)	0.004	0.996	0.000
N60.3 Fibrosclerosis of breast	0.000	0.996	0.004
M70.75 Other bursitis of hip-Pelvic/Thigh	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.004	0.996	0.000
S52.50 Fracture of lower end of radius (closed)	0.004	0.996	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.004	0.996	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.004	0.996	0.000
Y41.5 Antiviral drugs	0.004	0.996	0.000
M84.02 Malunion of fracture (Upper arm)	0.004	0.996	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.996	0.004
M70.56 Other bursitis of knee-Lower Leg	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
M84.09 Malunion of fracture (Site unspecified)	0.004	0.996	0.000
M84.08 Malunion of fracture (Other)	0.004	0.996	0.000
M84.00 Malunion of fracture (Multiple sites)	0.004	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.004	0.996	0.000
M84.06 Malunion of fracture (Lower leg)	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
Y54.4 Loop [high-ceiling] diuretics	0.004	0.996	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.996	0.000
Y45.4 Antirheumatics	0.003	0.996	0.000
N80.0 Endometriosis of uterus	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.003	0.996	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
M84.04 Malunion of fracture (Hand)	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
L73.8 Other specified follicular disorders	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
Z36 Antenatal screening	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
L73 Other follicular disorders	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.003	0.997	0.000
Y54.0 Mineralocorticoids	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
I70.0 Atherosclerosis of aorta	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
N76.2 Acute vulvitis	0.000	0.997	0.003
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.997	0.003
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.997	0.003
N36.2 Urethral caruncle	0.000	0.997	0.003
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
R82.9 Other and unspecified abnormal finding in urine	0.003	0.997	0.000
Y55.4 Expectorants	0.003	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.997	0.003
Y54.5 Other diuretics	0.003	0.997	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.997	0.003
L73.2 Hidradenitis suppurativa	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
Y55.5 Anticommon cold drugs	0.003	0.997	0.000
Y55.3 Antitussives	0.003	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
Y55.0 Oxytocic drugs	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.997	0.000
Y47.4 Bromine compounds	0.003	0.997	0.000
Y47.3 Paraldehyde	0.003	0.997	0.000
Y47.2 Chloral derivatives	0.003	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
H52.2 Astigmatism	0.000	0.997	0.003
M96.8 Other postprocedural musculoskeletal disorders	0.003	0.997	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.997	0.000
Y50.8 Other central nervous system stimulants	0.002	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.997	0.000
Y50.1 Opioid receptor antagonists	0.002	0.997	0.000
Y50.0 Analeptics	0.002	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
Y53.7 Emetics	0.002	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.997	0.000
Y53.5 Digestants	0.002	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y53.2 Stimulant laxatives	0.002	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.997	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.997	0.003
L73.1 Pseudofolliculitis barbae	0.003	0.997	0.000
L73.0 Acne keloid	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.002	0.997	0.000
Y48.1 Parenteral anaesthetics	0.002	0.997	0.000
Y48.0 Inhaled anaesthetics	0.002	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y40.6 Rifamycins	0.002	0.997	0.000
Y40.2 Chloramphenicol group	0.002	0.997	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.997	0.003
R82 Other abnormal findings in urine	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
Y59.0 Viral vaccines	0.002	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
Y48.3 Local anaesthetics	0.002	0.997	0.000
Y56.9 Topical agent, unspecified	0.002	0.997	0.000
Y56.8 Other topical agents	0.002	0.997	0.000
Y56.7 Dental drugs, topically applied	0.002	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
Y56.2 Local astringents and local detergents	0.002	0.997	0.000
Y56.1 Antipruritics	0.002	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.997	0.000
Y58.5 Diphtheria vaccine	0.002	0.997	0.000
Y58.4 Tetanus vaccine	0.002	0.997	0.000
Y58.3 Plague vaccine	0.002	0.997	0.000
Y58.2 Cholera vaccine	0.002	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.997	0.000
C71.3 Parietal lobe	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
Y44.5 Thrombolytic drugs	0.002	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.997	0.000
S02.50 Fracture of tooth (closed)	0.000	0.997	0.002
Y48.4 Anaesthetic, unspecified	0.002	0.997	0.000
G62.9 Polyneuropathy, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.000	0.998	0.002
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.998	0.002
Y58.0 BCG vaccine	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.000	0.998	0.002
I70 Atherosclerosis	0.002	0.998	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
C71.1 Frontal lobe	0.000	0.998	0.002
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
R82.4 Acetonuria	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R82.3 Haemoglobinuria	0.002	0.998	0.000
R82.2 Biliuria	0.002	0.998	0.000
R82.0 Chyluria	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
R82.1 Myoglobinuria	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.000	0.998	0.002
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.998	0.000
M96.5 Postradiation scoliosis	0.002	0.998	0.000
M96.4 Postsurgical lordosis	0.002	0.998	0.000
M96.3 Postlaminectomy kyphosis	0.002	0.998	0.000
M96.2 Postradiation kyphosis	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.998	0.002
C82.5 Diffuse follicle centre lymphoma	0.000	0.998	0.002
C82.4 Follicular lymphoma grade IIIb	0.000	0.998	0.002
C82.2 Large cell, follicular	0.000	0.998	0.002
R80 Isolated proteinuria	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.002	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.998	0.002
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.998	0.000
R17 Unspecified jaundice	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
K70 Alcoholic liver disease	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.002	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
T63.4 Venom of other arthropods	0.002	0.998	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
M65.34 Trigger finger-Hand	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.001	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.001	0.998	0.000
J35.1 Hypertrophy of tonsils	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations