TreeWAS – Variant ID: rs12429545

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E66.9 Obesity, unspecified	0.324	0.676
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.153	0.847
M06.9 Rheumatoid arthritis, unspecified	0.150	0.850
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.144	0.856
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.124	0.876
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.120	0.880
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.119	0.881
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.118	0.882
E66 Obesity	0.116	0.884
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.114	0.886
M06.98 Rheumatoid arthritis, unspecified (Other)	0.111	0.888
M06 Other rheumatoid arthritis	0.103	0.897
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.097	0.903
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.085	0.915
E66.1 Drug-induced obesity	0.083	0.917
M06.4 Inflammatory polyarthropathy	0.082	0.918
M06.3 Rheumatoid nodule	0.081	0.919
M06.0 Seronegative rheumatoid arthritis	0.077	0.923
E66.0 Obesity due to excess calories	0.077	0.923
E66.2 Extreme obesity with alveolar hypoventilation	0.076	0.924
E65-E68 Obesity and other hyperalimentation	0.075	0.925
M06.8 Other specified rheumatoid arthritis	0.074	0.926
M06.2 Rheumatoid bursitis	0.074	0.926
M06.1 Adult-onset Still's disease	0.074	0.926
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.074	0.926
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.066	0.934
M06.30 Rheumatoid nodule (Multiple sites)	0.065	0.935
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.064	0.936
M06.37 Rheumatoid nodule (Ankle and foot)	0.060	0.940
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.059	0.940
M06.48 Inflammatory polyarthropathy (Other)	0.059	0.941
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.059	0.941
M06.46 Inflammatory polyarthropathy (Lower leg)	0.059	0.941
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.059	0.941
M06.44 Inflammatory polyarthropathy (Hand)	0.059	0.941
M06.43 Inflammatory polyarthropathy (Forearm)	0.059	0.941
M06.42 Inflammatory polyarthropathy (Upper arm)	0.059	0.941
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.059	0.941
M06.39 Rheumatoid nodule (Site unspecified)	0.058	0.942
M06.38 Rheumatoid nodule (Other)	0.058	0.942
M06.36 Rheumatoid nodule (Lower leg)	0.058	0.942
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.058	0.942
M06.33 Rheumatoid nodule (Forearm)	0.058	0.942
M06.32 Rheumatoid nodule (Upper arm)	0.058	0.942
M06.31 Rheumatoid nodule (Shoulder region)	0.058	0.942
M06.34 Rheumatoid nodule (Hand)	0.056	0.944
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.056	0.944
M06.08 Seronegative rheumatoid arthritis (Other)	0.055	0.944
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.055	0.944
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.055	0.944
M06.04 Seronegative rheumatoid arthritis (Hand)	0.055	0.944
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.055	0.944
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.055	0.944
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.055	0.944
E65 Localised adiposity	0.054	0.946
E67 Other hyperalimentation	0.054	0.946
E68 Sequelae of hyperalimentation	0.054	0.946
M06.19 Adult-onset Still's disease (Site unspecified)	0.053	0.947
M06.18 Adult-onset Still's disease (Other)	0.053	0.947
M06.17 Adult-onset Still's disease (Ankle and foot)	0.053	0.947
M06.16 Adult-onset Still's disease (Lower leg)	0.053	0.947
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.053	0.947
M06.14 Adult-onset Still's disease (Hand)	0.053	0.947
M06.13 Adult-onset Still's disease (Forearm)	0.053	0.947
M06.12 Adult-onset Still's disease (Upper arm)	0.053	0.947
M06.11 Adult-onset Still's disease (Shoulder region)	0.053	0.947
M06.10 Adult-onset Still's disease (Multiple sites)	0.053	0.947
M06.29 Rheumatoid bursitis (Site unspecified)	0.053	0.947
M06.28 Rheumatoid bursitis (Other)	0.053	0.947
M06.27 Rheumatoid bursitis (Ankle and foot)	0.053	0.947
M06.26 Rheumatoid bursitis (Lower leg)	0.053	0.947
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.053	0.947
M06.24 Rheumatoid bursitis (Hand)	0.053	0.947
M06.23 Rheumatoid bursitis (Forearm)	0.053	0.947
M06.22 Rheumatoid bursitis (Upper arm)	0.053	0.947
M06.21 Rheumatoid bursitis (Shoulder region)	0.053	0.947
M06.20 Rheumatoid bursitis (Multiple sites)	0.053	0.947
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.053	0.947
M06.88 Other specified rheumatoid arthritis (Other)	0.053	0.947
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.053	0.947
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.053	0.947
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.053	0.947
M06.84 Other specified rheumatoid arthritis (Hand)	0.053	0.947
M06.83 Other specified rheumatoid arthritis (Forearm)	0.053	0.947
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.053	0.947
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.053	0.947
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.053	0.947
I80 Phlebitis and thrombophlebitis	0.053	0.947
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.050	0.950
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.047	0.953
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.046	0.954
Chapter IV Endocrine, nutritional and metabolic diseases	0.045	0.955
E20-E35 Disorders of other endocrine glands	0.044	0.956
E22 Hyperfunction of pituitary gland	0.042	0.958
E27 Other disorders of adrenal gland	0.042	0.958
H91.9 Hearing loss, unspecified	0.042	0.958
H91 Other hearing loss	0.042	0.958
H90-H95 Other disorders of ear	0.041	0.959
E27.8 Other specified disorders of adrenal gland	0.041	0.959
H92 Otalgia and effusion of ear	0.041	0.959
H92.0 Otalgia	0.041	0.959
V18.0 Driver injured in nontraffic accident	0.039	0.961
E67.8 Other specified hyperalimentation	0.039	0.961
E67.3 Hypervitaminosis D	0.039	0.961
E67.2 Megavitamin-B6 syndrome	0.039	0.961
E67.1 Hypercarotenaemia	0.039	0.961
E67.0 Hypervitaminosis A	0.039	0.961
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.039	0.961
V18 Pedal cyclist injured in noncollision transport accident	0.039	0.961
H90 Conductive and sensorineural hearing loss	0.038	0.962
E22.1 Hyperprolactinaemia	0.038	0.962
E22.0 Acromegaly and pituitary gigantism	0.038	0.962
V10-V19 Pedal cyclist injured in transport accident	0.037	0.963
E27.9 Disorder of adrenal gland, unspecified	0.037	0.963
E24 Cushing's syndrome	0.037	0.963
E10-E14 Diabetes mellitus	0.037	0.963
E66.8 Other obesity	0.036	0.964
Chapter XX External causes of morbidity and mortality	0.036	0.964
M05-M14 Inflammatory polyarthropathies	0.035	0.965
E28 Ovarian dysfunction	0.034	0.966
V18.3 Person injured while boarding or alighting	0.033	0.967
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.033	0.967
W20-W49 Exposure to inanimate mechanical forces	0.033	0.967
H92.2 Otorrhagia	0.032	0.968
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.032	0.968
H91.3 Deaf mutism, not elsewhere classified	0.032	0.968
X60-X84 Intentional self-harm	0.032	0.968
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.032	0.968
H91.8 Other specified hearing loss	0.032	0.968
E11.3 With ophthalmic complications	0.032	0.968
E35 Disorders of endocrine glands in diseases classified elsewhere	0.032	0.968
E32 Diseases of thymus	0.032	0.968
E31 Polyglandular dysfunction	0.032	0.968
E30 Disorders of puberty, not elsewhere classified	0.032	0.968
E25 Adrenogenital disorders	0.032	0.968
E20 Hypoparathyroidism	0.032	0.968
E50-E64 Other nutritional deficiencies	0.032	0.968
E27.3 Drug-induced adrenocortical insufficiency	0.031	0.968
E27.4 Other and unspecified adrenocortical insufficiency	0.031	0.969
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.031	0.969
H90.0 Conductive hearing loss, bilateral	0.031	0.969
E26 Hyperaldosteronism	0.031	0.969
E22.9 Hyperfunction of pituitary gland, unspecified	0.030	0.969
E22.8 Other hyperfunction of pituitary gland	0.030	0.969
I80.8 Phlebitis and thrombophlebitis of other sites	0.030	0.969
E27.5 Adrenomedullary hyperfunction	0.030	0.969
E27.2 Addisonian crisis	0.030	0.969
E27.0 Other adrenocortical overactivity	0.030	0.969
H90.2 Conductive hearing loss, unspecified	0.030	0.970
E24.9 Cushing's syndrome, unspecified	0.030	0.970
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.030	0.970
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.030	0.970
H91.2 Sudden idiopathic hearing loss	0.030	0.970
H91.1 Presbycusis	0.030	0.970
H91.0 Ototoxic hearing loss	0.030	0.970
W50-W64 Exposure to animate mechanical forces	0.030	0.970
H94 Other disorders of ear in diseases classified elsewhere	0.030	0.970
H90.5 Sensorineural hearing loss, unspecified	0.030	0.970
E11 Non-insulin-dependent diabetes mellitus	0.030	0.970
V20-V29 Motorcycle rider injured in transport accident	0.030	0.970
H93 Other disorders of ear, not elsewhere classified	0.029	0.971
W22 Striking against or struck by other objects	0.029	0.971
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.029	0.971
Y41 Other systemic anti-infectives and antiparasitics	0.029	0.971
H90.3 Sensorineural hearing loss, bilateral	0.029	0.971
E28.3 Primary ovarian failure	0.029	0.971
Y79 Orthopaedic devices associated with adverse incidents	0.029	0.971
E24.0 Pituitary-dependent Cushing's disease	0.029	0.971
E00-E07 Disorders of thyroid gland	0.029	0.971
E14 Unspecified diabetes mellitus	0.029	0.971
M05 Seropositive rheumatoid arthritis	0.029	0.971
H92.1 Otorrhoea	0.029	0.971
V17 Pedal cyclist injured in collision with fixed or stationary object	0.028	0.971
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.029	0.971
W75-W84 Other accidental threats to breathing	0.028	0.972
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.028	0.972
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.028	0.972
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.028	0.972
V18.9 Unspecified pedal cyclist injured in traffic accident	0.028	0.972
V18.4 Driver injured in traffic accident	0.028	0.972
V18.5 Passenger injured in traffic accident	0.028	0.972
V18.1 Passenger injured in nontraffic accident	0.028	0.972
W25 Contact with sharp glass	0.028	0.972
F05.9 Delirium, unspecified	0.028	0.972
X50-X57 Overexertion, travel and privation	0.028	0.972
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.027	0.972
E13 Other specified diabetes mellitus	0.027	0.972
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.027	0.973
F05 Delirium, not induced by alcohol and other psychoactive substances	0.027	0.973
Y53 Agents primarily affecting the gastro-intestinal system	0.027	0.973
W23 Caught, crushed, jammed or pinched in or between objects	0.027	0.973
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.027	0.973
E05 Thyrotoxicosis [hyperthyroidism]	0.027	0.973
E40-E46 Malnutrition	0.027	0.973
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.027	0.973
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.027	0.973
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.027	0.973
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.027	0.973
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.027	0.973
V11 Pedal cyclist injured in collision with other pedal cycle	0.027	0.973
V10 Pedal cyclist injured in collision with pedestrian or animal	0.027	0.973
E24.8 Other Cushing's syndrome	0.026	0.973
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.026	0.973
E24.3 Ectopic ACTH syndrome	0.026	0.973
E24.2 Drug-induced Cushing's syndrome	0.026	0.973
E24.1 Nelson's syndrome	0.026	0.973
Y49 Psychotropic drugs, not elsewhere classified	0.027	0.973
E12 Malnutrition-related diabetes mellitus	0.026	0.973
X00-X09 Exposure to smoke, fire and flames	0.026	0.974
E05.0 Thyrotoxicosis with diffuse goitre	0.026	0.974
W29 Contact with other powered hand tools and household machinery	0.026	0.974
E14.3 With ophthalmic complications	0.026	0.974
E55 Vitamin D deficiency	0.026	0.974
Y35-Y36 Legal intervention and operations of war	0.026	0.974
Y10-Y34 Event of undetermined intent	0.026	0.974
X85-X99 Assault	0.026	0.974
X30-X39 Exposure to forces of nature	0.026	0.974
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.026	0.974
W65-W74 Accidental drowning and submersion	0.026	0.974
V95-V97 Air and space transport accidents	0.026	0.974
V90-V94 Water transport accidents	0.026	0.974
V70-V79 Bus occupant injured in transport accident	0.026	0.974
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.026	0.974
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.026	0.974
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.026	0.974
V19 Pedal cyclist injured in other and unspecified transport accidents	0.026	0.974
X68 Intentional self-poisoning by and exposure to pesticides	0.026	0.974
Y00-Y09 Assault	0.026	0.974
V80-V89 Other land transport accidents	0.025	0.974
M12 Other specific arthropathies	0.025	0.974
M09 Juvenile arthritis in diseases classified elsewhere	0.025	0.974
M08 Juvenile arthritis	0.025	0.974
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.025	0.975
Y46 Antiepileptics and anti-Parkinsonism drugs	0.025	0.975
V01-V09 Pedestrian injured in transport accident	0.025	0.975
F00-F09 Organic, including symptomatic, mental disorders	0.025	0.975
W22.2 School, other institution and public administrative area	0.025	0.975
X78 Intentional self-harm by sharp object	0.025	0.975
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.025	0.975
X58-X59 Accidental exposure to other and unspecified factors	0.025	0.975
E28.9 Ovarian dysfunction, unspecified	0.025	0.975
E28.8 Other ovarian dysfunction	0.025	0.975
E28.1 Androgen excess	0.025	0.975
E28.0 Oestrogen excess	0.025	0.975
W55 Bitten or struck by other mammals	0.025	0.975
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.025	0.975
Y79.2 Prosthetic and other implants, materials and accessory devices	0.025	0.975
W00-W19 Falls	0.025	0.975
X10-X19 Contact with heat and hot substances	0.025	0.975
M14 Arthropathies in other diseases classified elsewhere	0.025	0.975
Y77 Ophthalmic devices associated with adverse incidents	0.025	0.975
W22.9 Unspecified place	0.025	0.975
W45 Foreign body or object entering through skin	0.024	0.975
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.024	0.975
V98-V99 Other and unspecified transport accidents	0.024	0.975
E11.4 With neurological complications	0.024	0.976
W24 Contact with lifting and transmission devices, not elsewhere classified	0.024	0.976
E10 Insulin-dependent diabetes mellitus	0.024	0.976
Y71 Cardiovascular devices associated with adverse incidents	0.024	0.976
M07 Psoriatic and enteropathic arthropathies	0.024	0.976
W25.9 Unspecified place	0.024	0.976
E07 Other disorders of thyroid	0.024	0.976
X65 Intentional self-poisoning by and exposure to alcohol	0.024	0.976
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.024	0.976
V28 Motorcycle rider injured in noncollision transport accident	0.024	0.976
Y82 Other and unspecified medical devices associated with adverse incidents	0.024	0.976
Y81 General- and plastic-surgery devices associated with adverse incidents	0.024	0.976
Y80 Physical medicine devices associated with adverse incidents	0.024	0.976
Y78 Radiological devices associated with adverse incidents	0.024	0.976
Y75 Neurological devices associated with adverse incidents	0.024	0.976
Y74 General hospital and personal-use devices associated with adverse incidents	0.024	0.976
Y72 Otorhinolaryngological devices associated with adverse incidents	0.024	0.976
Y70 Anaesthesiology devices associated with adverse incidents	0.024	0.976
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.024	0.976
W60 Contact with plant thorns and spines and sharp leaves	0.024	0.976
M05.9 Seropositive rheumatoid arthritis, unspecified	0.024	0.976
W49 Exposure to other and unspecified inanimate mechanical forces	0.024	0.976
W46 Contact with hypodermic needle	0.024	0.976
W43 Exposure to vibration	0.024	0.976
W42 Exposure to noise	0.024	0.976
W41 Exposure to high-pressure jet	0.024	0.976
W40 Explosion of other materials	0.024	0.976
W39 Discharge of firework	0.024	0.976
W38 Explosion and rupture of other specified pressurised devices	0.024	0.976
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.024	0.976
W36 Explosion and rupture of gas cylinder	0.024	0.976
W35 Explosion and rupture of boiler	0.024	0.976
W34 Discharge from other and unspecified firearms	0.024	0.976
W33 Rifle, shotgun and larger firearm discharge	0.024	0.976
W32 Handgun discharge	0.024	0.976
W31 Contact with other and unspecified machinery	0.024	0.976
W30 Contact with agricultural machinery	0.024	0.976
W28 Contact with powered lawn mower	0.024	0.976
W27 Contact with nonpowered hand tool	0.024	0.976
W26 Contact with knife, sword or dagger	0.024	0.976
Y76.2 Prosthetic and other implants, materials and accessory devices	0.024	0.976
E23 Hypofunction and other disorders of pituitary gland	0.024	0.976
Chapter V Mental and behavioural disorders	0.023	0.977
E29 Testicular dysfunction	0.023	0.977
Y47 Sedatives, hypnotics and antianxiety drugs	0.023	0.977
Y53.1 Other antacids and anti-gastric-secretion drugs	0.023	0.977
Y59 Other and unspecified vaccines and biological substances	0.023	0.977
E10.1 With ketoacidosis	0.023	0.977
Y49.0 Tricyclic and tetracyclic antidepressants	0.023	0.977
Y43 Primarily systemic agents	0.023	0.977
X20-X29 Contact with venomous animals and plants	0.023	0.977
Chapter XII Diseases of the skin and subcutaneous tissue	0.023	0.977
H93.2 Other abnormal auditory perceptions	0.023	0.977
X84 Intentional self-harm by unspecified means	0.023	0.977
X83 Intentional self-harm by other specified means	0.023	0.977
X82 Intentional self-harm by crashing of motor vehicle	0.023	0.977
X81 Intentional self-harm by jumping or lying before moving object	0.023	0.977
X80 Intentional self-harm by jumping from a high place	0.023	0.977
X79 Intentional self-harm by blunt object	0.023	0.977
X77 Intentional self-harm by steam, hot vapours and hot objects	0.023	0.977
X76 Intentional self-harm by smoke, fire and flames	0.023	0.977
X75 Intentional self-harm by explosive material	0.023	0.977
X74 Intentional self-harm by other and unspecified firearm discharge	0.023	0.977
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.023	0.977
X72 Intentional self-harm by handgun discharge	0.023	0.977
X71 Intentional self-harm by drowning and submersion	0.023	0.977
X70 Intentional self-harm by hanging, strangulation and suffocation	0.023	0.977
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.023	0.977
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.023	0.977
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.023	0.977
F05.0 Delirium not superimposed on dementia, so described	0.023	0.977
Y60-Y69 Misadventures to patients during surgical and medical care	0.023	0.977
E25.9 Adrenogenital disorder, unspecified	0.023	0.977
E25.8 Other adrenogenital disorders	0.023	0.977
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.023	0.977
E30.9 Disorder of puberty, unspecified	0.023	0.977
E30.8 Other disorders of puberty	0.023	0.977
E30.1 Precocious puberty	0.023	0.977
E30.0 Delayed puberty	0.023	0.977
E31.9 Polyglandular dysfunction, unspecified	0.023	0.977
E31.8 Other polyglandular dysfunction	0.023	0.977
E31.1 Polyglandular hyperfunction	0.023	0.977
E31.0 Autoimmune polyglandular failure	0.023	0.977
E32.9 Disease of thymus, unspecified	0.023	0.977
E32.8 Other diseases of thymus	0.023	0.977
E32.1 Abscess of thymus	0.023	0.977
E32.0 Persistent hyperplasia of thymus	0.023	0.977
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.023	0.977
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.023	0.977
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.023	0.977
Y79.3 Surgical instruments, materials and devices (including sutures)	0.023	0.977
E20.8 Other hypoparathyroidism	0.023	0.977
E20.1 Pseudohypoparathyroidism	0.023	0.977
E20.0 Idiopathic hypoparathyroidism	0.023	0.977
L03 Cellulitis	0.023	0.977
E64 Sequelae of malnutrition and other nutritional deficiencies	0.023	0.977
E63 Other nutritional deficiencies	0.023	0.977
E56 Other vitamin deficiencies	0.023	0.977
E51 Thiamine deficiency	0.023	0.977
E50 Vitamin A deficiency	0.023	0.977
E60 Dietary zinc deficiency	0.023	0.977
E59 Dietary selenium deficiency	0.023	0.977
E58 Dietary calcium deficiency	0.023	0.977
E54 Ascorbic acid deficiency	0.023	0.977
E52 Niacin deficiency [pellagra]	0.023	0.977
Y52 Agents primarily affecting the cardiovascular system	0.023	0.977
E20.9 Hypoparathyroidism, unspecified	0.023	0.977
Y51 Drugs primarily affecting the autonomic nervous system	0.023	0.977
Y48 Anaesthetics and therapeutic gases	0.023	0.977
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.022	0.977
E28.2 Polycystic ovarian syndrome	0.022	0.977
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.023	0.977
E14.1 With ketoacidosis	0.022	0.977
Y58 Bacterial vaccines	0.022	0.977
Y50 Central nervous system stimulants, not elsewhere classified	0.022	0.977
H93.1 Tinnitus	0.022	0.978
L00-L08 Infections of the skin and subcutaneous tissue	0.022	0.978
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.022	0.978
V27 Motorcycle rider injured in collision with fixed or stationary object	0.022	0.978
E26.9 Hyperaldosteronism, unspecified	0.022	0.978
E26.8 Other hyperaldosteronism	0.022	0.978
E26.1 Secondary hyperaldosteronism	0.022	0.978
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.022	0.978
L03.0 Cellulitis of finger and toe	0.022	0.978
X51 Travel and motion	0.022	0.978
M11 Other crystal arthropathies	0.022	0.978
L50-L54 Urticaria and erythema	0.022	0.978
W08 Fall involving other furniture	0.022	0.978
E13.3 With ophthalmic complications	0.022	0.978
F05.8 Other delirium	0.022	0.978
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.022	0.978
E15 Nondiabetic hypoglycaemic coma	0.022	0.978
E11.8 With unspecified complications	0.022	0.978
V17.4 Driver injured in traffic accident	0.022	0.978
E55.9 Vitamin D deficiency, unspecified	0.022	0.978
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.022	0.978
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.022	0.978
W64 Exposure to other and unspecified animate mechanical forces	0.022	0.978
W59 Bitten or crushed by other reptiles	0.022	0.978
W58 Bitten or struck by crocodile or alligator	0.022	0.978
W56 Contact with marine animal	0.022	0.978
W54 Bitten or struck by dog	0.022	0.978
W53 Bitten by rat	0.022	0.978
W52 Crushed, pushed and stepped on by crowd or human stampede	0.022	0.978
W51 Striking against or bumped into by another person	0.022	0.978
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.022	0.978
W79 Inhalation and ingestion of food causing obstruction of respiratory tract	0.022	0.978
F80-F89 Disorders of psychological development	0.022	0.978
Y46.2 Hydantoin derivatives	0.022	0.978
V17.0 Driver injured in nontraffic accident	0.021	0.978
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.022	0.978
Y41.5 Antiviral drugs	0.021	0.978
E11.7 With multiple complications	0.021	0.978
W23.4 Street and highway	0.021	0.978
E34 Other endocrine disorders	0.021	0.978
V29 Motorcycle rider injured in other and unspecified transport accidents	0.021	0.978
V26 Motorcycle rider injured in collision with other nonmotor vehicle	0.021	0.978
V25 Motorcycle rider injured in collision with railway train or railway vehicle	0.021	0.978
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus	0.021	0.978
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.021	0.978
V21 Motorcycle rider injured in collision with pedal cycle	0.021	0.978
V20 Motorcycle rider injured in collision with pedestrian or animal	0.021	0.978
L03.9 Cellulitis, unspecified	0.021	0.979
E61 Deficiency of other nutrient elements	0.021	0.979
W23.2 School, other institution and public administrative area	0.021	0.979
W20 Struck by thrown, projected or falling object	0.021	0.979
L50 Urticaria	0.021	0.979
W84 Unspecified threat to breathing	0.021	0.979
W78 Inhalation of gastric contents	0.021	0.979
E26.0 Primary hyperaldosteronism	0.021	0.979
H93.3 Disorders of acoustic nerve	0.021	0.979
H93.0 Degenerative and vascular disorders of ear	0.021	0.979
W22.8 Other specified place	0.021	0.979
W22.6 Industrial and construction area	0.021	0.979
W22.4 Street and highway	0.021	0.979
W22.0 Home	0.021	0.979
W22.7 Farm	0.021	0.979
W22.5 Trade and service area	0.021	0.979
W22.1 Residential institution	0.021	0.979
X68.9 Unspecified place	0.021	0.979
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.021	0.979
Y41.4 Anthelminthics	0.021	0.979
Y41.3 Other antiprotozoal drugs	0.021	0.979
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.021	0.979
Y41.1 Antimycobacterial drugs	0.021	0.979
Y41.0 Sulphonamides	0.021	0.979
Chapter VIII Diseases of the ear and mastoid process	0.021	0.979
# Top node	0.021	0.979
Y53.4 Other laxatives	0.021	0.979
M10 Gout	0.021	0.979
Y57 Other and unspecified drugs and medicaments	0.021	0.979
W29.9 Unspecified place	0.021	0.979
V40-V49 Car occupant injured in transport accident	0.021	0.979
Y79.8 Miscellaneous devices, not elsewhere classified	0.021	0.979
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.021	0.979
Y79.0 Diagnostic and monitoring devices	0.021	0.979
L03.2 Cellulitis of face	0.021	0.979
W03 Other fall on same level due to collision with, or pushing by, another person	0.021	0.979
F52 Sexual dysfunction, not caused by organic disorder or disease	0.021	0.979
E21.0 Primary hyperparathyroidism	0.021	0.979
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.021	0.979
E00 Congenital iodine-deficiency syndrome	0.021	0.979
E02 Subclinical iodine-deficiency hypothyroidism	0.021	0.979
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.021	0.979
X67.9 Unspecified place	0.021	0.979
X40-X49 Accidental poisoning by and exposure to noxious substances	0.021	0.979
W17 Other fall from one level to another	0.021	0.979
E11.5 With peripheral circulatory complications	0.021	0.979
L50.9 Urticaria, unspecified	0.021	0.979
Q60-Q64 Congenital malformations of the urinary system	0.021	0.979
E14.8 With unspecified complications	0.021	0.979
E14.7 With multiple complications	0.021	0.979
E14.6 With other specified complications	0.021	0.979
E14.5 With peripheral circulatory complications	0.021	0.979
E14.2 Withrenal complications	0.021	0.979
E14.0 With coma	0.021	0.979
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.021	0.979
M05.8 Other seropositive rheumatoid arthritis	0.021	0.979
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.021	0.979
M05.2 Rheumatoid vasculitis	0.021	0.979
M05.1 Rheumatoid lung disease	0.021	0.979
M05.0 Felty's syndrome	0.021	0.979
V17.9 Unspecified pedal cyclist injured in traffic accident	0.021	0.979
V17.5 Passenger injured in traffic accident	0.021	0.979
V17.3 Person injured while boarding or alighting	0.021	0.979
V17.2 Unspecified pedal cyclist injured in nontraffic accident	0.021	0.979
V17.1 Passenger injured in nontraffic accident	0.021	0.979
E21.5 Disorder of parathyroid gland, unspecified	0.021	0.979
E21.4 Other specified disorders of parathyroid gland	0.021	0.979
E21.2 Other hyperparathyroidism	0.021	0.979
L20-L30 Dermatitis and eczema	0.021	0.979
H93.8 Other specified disorders of ear	0.021	0.979
E21.3 Hyperparathyroidism, unspecified	0.021	0.979
Q00-Q07 Congenital malformations of the nervous system	0.021	0.979
L29 Pruritus	0.021	0.979
E14.4 With neurological complications	0.020	0.979
W83 Other specified threats to breathing	0.020	0.979
W81 Confined to or trapped in a low-oxygen environment	0.020	0.979
W80 Inhalation and ingestion of other objects causing obstruction of respiratory tract	0.020	0.979
W77 Threat to breathing due to cave-in, falling earth and other substances	0.020	0.979
W76 Other accidental hanging and strangulation	0.020	0.979
W75 Accidental suffocation and strangulation in bed	0.020	0.979
Y43.0 Antiallergic and antiemetic drugs	0.021	0.979
F52.2 Failure of genital response	0.020	0.979
W22.3 Sports and athletics area	0.020	0.979

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations