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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12438181
log Bayes Factor = 19.7958
Chromosome 15   position 78,812,098  (GRCh37) Explore rs12438181 on Ensembl!
Variant rs12438181 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.003 0.997
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.004 0.996
J90-J94 Other diseases of pleura
0.000 0.005 0.995
I73 Other peripheral vascular diseases
0.000 0.007 0.993
I70 Atherosclerosis
0.000 0.008 0.992
J92 Pleural plaque
0.000 0.009 0.991
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.014 0.986
I60-I69 Cerebrovascular diseases
0.000 0.015 0.985
I73.9 Peripheral vascular disease, unspecified
0.000 0.016 0.984
Chapter IX Diseases of the circulatory system
0.000 0.016 0.984
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.018 0.982
J42 Unspecified chronic bronchitis
0.000 0.020 0.980
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.023 0.977
J92.0 Pleural plaque with presence of asbestos
0.000 0.026 0.974
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.027 0.973
J60-J70 Lung diseases due to external agents
0.000 0.028 0.972
I60 Subarachnoid haemorrhage
0.000 0.030 0.970
J95-J99 Other diseases of the respiratory system
0.000 0.030 0.970
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.037 0.963
J98 Other respiratory disorders
0.000 0.049 0.951
I67 Other cerebrovascular diseases
0.000 0.050 0.950
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.051 0.949
I69 Sequelae of cerebrovascular disease
0.000 0.053 0.947
J98.1 Pulmonary collapse
0.000 0.056 0.944
I26 Pulmonary embolism
0.000 0.058 0.942
I27 Other pulmonary heart diseases
0.000 0.061 0.939
J92.9 Pleural plaque without asbestos
0.000 0.062 0.938
J90 Pleural effusion, not elsewhere classified
0.000 0.070 0.930
I77 Other disorders of arteries and arterioles
0.000 0.070 0.930
I27.9 Pulmonary heart disease, unspecified
0.000 0.081 0.919
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.094 0.906
I67.9 Cerebrovascular disease, unspecified
0.000 0.102 0.898
I73.0 Raynaud's syndrome
0.000 0.109 0.891
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.110 0.890
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.110 0.890
I69.3 Sequelae of cerebral infarction
0.000 0.111 0.889
I72 Other aneurysm
0.000 0.127 0.873
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.137 0.863
J86 Pyothorax
0.000 0.146 0.854
I60.8 Other subarachnoid haemorrhage
0.000 0.149 0.851
J98.4 Other disorders of lung
0.000 0.157 0.843
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.163 0.837
I77.1 Stricture of artery
0.000 0.165 0.835
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.165 0.835
J43.2 Centrilobular emphysema
0.000 0.168 0.832
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.171 0.829
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.177 0.823
J93 Pneumothorax
0.000 0.177 0.823
I67.1 Cerebral aneurysm, nonruptured
0.000 0.178 0.822
I67.8 Other specified cerebrovascular diseases
0.000 0.178 0.822
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.178 0.822
J86.9 Pyothorax without fistula
0.000 0.179 0.820
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.189 0.811
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.195 0.805
I77.0 Arteriovenous fistula, acquired
0.000 0.198 0.802
I72.0 Aneurysm of carotid artery
0.000 0.205 0.795
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.213 0.787
I71.0 Dissection of aorta [any part]
0.000 0.215 0.785
J98.9 Respiratory disorder, unspecified
0.000 0.230 0.770
J60 Coalworker's pneumoconiosis
0.000 0.232 0.768
I70.0 Atherosclerosis of aorta
0.000 0.233 0.767
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.235 0.765
J93.1 Other spontaneous pneumothorax
0.000 0.242 0.758
J64 Unspecified pneumoconiosis
0.000 0.248 0.751
I61 Intracerebral haemorrhage
0.000 0.265 0.735
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.271 0.729
I72.8 Aneurysm of other specified arteries
0.000 0.272 0.728
I77.2 Rupture of artery
0.000 0.272 0.728
J69 Pneumonitis due to solids and liquids
0.000 0.277 0.723
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.280 0.720
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.288 0.712
I28 Other diseases of pulmonary vessels
0.000 0.288 0.712
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.293 0.706
I78 Diseases of capillaries
0.000 0.296 0.704
I00-I02 Acute rheumatic fever
0.000 0.298 0.702
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.298 0.701
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.303 0.697
J66 Airway disease due to specific organic dust
0.000 0.303 0.697
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.303 0.697
J62 Pneumoconiosis due to dust containing silica
0.000 0.303 0.697
J65 Pneumoconiosis associated with tuberculosis
0.000 0.303 0.697
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.303 0.696
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.305 0.695
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.305 0.695
J96 Respiratory failure, not elsewhere classified
0.000 0.305 0.695
J98.2 Interstitial emphysema
0.000 0.305 0.695
I27.8 Other specified pulmonary heart diseases
0.000 0.309 0.691
I27.0 Primary pulmonary hypertension
0.000 0.314 0.686
J98.3 Compensatory emphysema
0.000 0.318 0.682
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.318 0.681
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.318 0.681
I67.5 Moyamoya disease
0.000 0.318 0.681
I67.4 Hypertensive encephalopathy
0.000 0.318 0.681
I67.3 Progressive vascular leukoencephalopathy
0.000 0.318 0.681
I27.1 Kyphoscoliotic heart disease
0.000 0.327 0.673
I72.9 Aneurysm of unspecified site
0.000 0.331 0.669
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.333 0.667
I77.5 Necrosis of artery
0.000 0.333 0.667
I77.4 Coeliac artery compression syndrome
0.000 0.333 0.667
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.334 0.665
J40 Bronchitis, not specified as acute or chronic
0.000 0.343 0.657
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.346 0.654
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.350 0.650
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.350 0.650
I74 Arterial embolism and thrombosis
0.000 0.350 0.650
J70 Respiratory conditions due to other external agents
0.000 0.358 0.642
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.362 0.638
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.374 0.626
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.374 0.626
I72.1 Aneurysm of artery of upper extremity
0.000 0.374 0.626
I73.8 Other specified peripheral vascular diseases
0.000 0.376 0.624
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.377 0.623
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.378 0.622
J93.0 Spontaneous tension pneumothorax
0.000 0.388 0.611
I70.1 Atherosclerosis of renal artery
0.000 0.391 0.608
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.395 0.605
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.396 0.604
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.399 0.601
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.410 0.590
I79.1 Aortitis in diseases classified elsewhere
0.000 0.410 0.590
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.410 0.590
J85 Abscess of lung and mediastinum
0.000 0.411 0.589
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.416 0.584
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.416 0.584
J86.0 Pyothorax with fistula
0.000 0.418 0.581
J43.8 Other emphysema
0.000 0.423 0.577
J98.6 Disorders of diaphragm
0.000 0.429 0.571
I72.3 Aneurysm of iliac artery
0.000 0.436 0.564
J99.0 Rheumatoid lung disease
0.000 0.439 0.561
I77.8 Other specified disorders of arteries and arterioles
0.000 0.441 0.559
J69.8 Pneumonitis due to other solids and liquids
0.000 0.441 0.559
J94 Other pleural conditions
0.000 0.443 0.557
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.450 0.550
I77.3 Arterial fibromuscular dysplasia
0.000 0.451 0.549
J09-J18 Influenza and pneumonia
0.000 0.454 0.546
I77.6 Arteritis, unspecified
0.000 0.454 0.546
I05-I09 Chronic rheumatic heart diseases
0.000 0.462 0.538
I67.2 Cerebral atherosclerosis
0.000 0.462 0.537
J93.8 Other pneumothorax
0.000 0.463 0.537
I72.2 Aneurysm of renal artery
0.000 0.466 0.534
I27.2 Other secondary pulmonary hypertension
0.000 0.473 0.527
I72.4 Aneurysm of artery of lower extremity
0.000 0.477 0.523
I28.8 Other specified diseases of pulmonary vessels
0.000 0.479 0.521
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.479 0.520
J69.1 Pneumonitis due to oils and essences
0.000 0.482 0.518
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.484 0.516
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.490 0.510
I28.1 Aneurysm of pulmonary artery
0.000 0.490 0.510
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.490 0.510
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I62 Other nontraumatic intracranial haemorrhage
0.000 0.490 0.509
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.493 0.507
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.493 0.507
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.493 0.507
I68.0 Cerebral amyloid angiopathy
0.000 0.493 0.507
J95.8 Other postprocedural respiratory disorders
0.000 0.495 0.505
I78.9 Disease of capillaries, unspecified
0.000 0.495 0.505
I02 Rheumatic chorea
0.000 0.497 0.503
I01 Rheumatic fever with heart involvement
0.000 0.497 0.503
J46 Status asthmaticus
0.000 0.499 0.501
J69.0 Pneumonitis due to food and vomit
0.000 0.500 0.500
I00 Rheumatic fever without mention of heart involvement
0.000 0.500 0.500
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.500 0.499
J62.0 Pneumoconiosis due to talc dust
0.000 0.500 0.499
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.500 0.499
J63.5 Stannosis
0.000 0.500 0.499
J63.4 Siderosis
0.000 0.500 0.499
J63.3 Graphite fibrosis (of lung)
0.000 0.500 0.499
J63.2 Berylliosis
0.000 0.500 0.499
J63.1 Bauxite fibrosis (of lung)
0.000 0.500 0.499
J63.0 Aluminosis (of lung)
0.000 0.500 0.499
J66.8 Airway disease due to other specific organic dusts
0.000 0.500 0.499
J66.2 Cannabinosis
0.000 0.500 0.499
J66.1 Flax-dresser's disease
0.000 0.500 0.499
J66.0 Byssinosis
0.000 0.500 0.499
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.500 0.499
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.500 0.499
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.500 0.499
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.500 0.499
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.500 0.499
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.500 0.499
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.500 0.499
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.501 0.499
J96.9 Respiratory failure, unspecified
0.000 0.501 0.498
J96.1 Chronic respiratory failure
0.000 0.501 0.498
J96.0 Acute respiratory failure
0.000 0.501 0.498
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.501 0.498
J91 Pleural effusion in conditions classified elsewhere
0.000 0.504 0.496
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.508 0.492
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.512 0.488
I78.8 Other diseases of capillaries
0.000 0.515 0.484
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.518 0.482
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.520 0.480
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.521 0.479
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.523 0.477
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.523 0.477
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.523 0.477
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.523 0.477
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.529 0.471
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.534 0.466
J18 Pneumonia, organism unspecified
0.000 0.538 0.462
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.539 0.460
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.540 0.460
J70.8 Respiratory conditions due to other specified external agents
0.000 0.540 0.460
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.540 0.460
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.540 0.460
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.540 0.460
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.540 0.460
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.541 0.459
I74.8 Embolism and thrombosis of other arteries
0.000 0.541 0.458
J95.5 Postprocedural subglottic stenosis
0.000 0.542 0.457
J95.4 Mendelson's syndrome
0.000 0.542 0.457
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.542 0.457
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.542 0.457
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.542 0.457
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.544 0.456
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.545 0.455
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.548 0.451
J18.1 Lobar pneumonia, unspecified
0.000 0.552 0.448
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.553 0.447
J67.7 Air-conditioner and humidifier lung
0.000 0.553 0.447
J67.6 Maple-bark-stripper's lung
0.000 0.553 0.447
J67.5 Mushroom-worker's lung
0.000 0.553 0.447
J67.4 Maltworker's lung
0.000 0.553 0.447
J67.3 Suberosis
0.000 0.553 0.447
J67.1 Bagassosis
0.000 0.553 0.447
J67.0 Farmer's lung
0.000 0.553 0.447
J98.8 Other specified respiratory disorders
0.000 0.562 0.438
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.564 0.436
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.564 0.435
I09 Other rheumatic heart diseases
0.000 0.567 0.432
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.568 0.432
I74.5 Embolism and thrombosis of iliac artery
0.000 0.569 0.431
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.570 0.429
J10 Influenza due to identified influenza virus
0.000 0.572 0.428
J93.9 Pneumothorax, unspecified
0.000 0.573 0.427
J85.1 Abscess of lung with pneumonia
0.000 0.576 0.423
J85.3 Abscess of mediastinum
0.000 0.578 0.422
J85.0 Gangrene and necrosis of lung
0.000 0.578 0.422
I07 Rheumatic tricuspid valve diseases
0.000 0.579 0.421
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.582 0.418
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.586 0.413
J67.2 Bird fancier's lung
0.000 0.587 0.412
J20-J22 Other acute lower respiratory infections
0.000 0.594 0.406
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.594 0.405
I61.8 Other intracerebral haemorrhage
0.000 0.597 0.403
J95.0 Tracheostomy malfunction
0.000 0.598 0.402
J94.9 Pleural condition, unspecified
0.000 0.601 0.399
J94.0 Chylous effusion
0.000 0.601 0.399
J94.1 Fibrothorax
0.000 0.601 0.399
J94.8 Other specified pleural conditions
0.000 0.602 0.398
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.604 0.396
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.608 0.392
J09 Influenza due to certain identified influenza virus
0.000 0.608 0.392
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.609 0.391
I05 Rheumatic mitral valve diseases
0.000 0.614 0.386
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.617 0.383
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.618 0.382
J17 Pneumonia in diseases classified elsewhere
0.000 0.629 0.371
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.638 0.362
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.639 0.361
I01.8 Other acute rheumatic heart disease
0.000 0.639 0.361
I01.2 Acute rheumatic myocarditis
0.000 0.639 0.361
I01.1 Acute rheumatic endocarditis
0.000 0.639 0.361
I01.0 Acute rheumatic pericarditis
0.000 0.639 0.361
I02.9 Rheumatic chorea without heart involvement
0.000 0.639 0.361
I02.0 Rheumatic chorea with heart involvement
0.000 0.639 0.361
J85.2 Abscess of lung without pneumonia
0.000 0.640 0.359
J96.09 Acute respiratory failure; Type unspecified
0.000 0.642 0.357
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.642 0.357
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.642 0.357
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.642 0.357
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.642 0.357
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.642 0.357
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.642 0.357
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.642 0.357
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.642 0.357
I06 Rheumatic aortic valve diseases
0.000 0.643 0.357
I09.9 Rheumatic heart disease, unspecified
0.000 0.643 0.357
J12 Viral pneumonia, not elsewhere classified
0.000 0.649 0.350
I07.1 Tricuspid insufficiency
0.000 0.663 0.337
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.665 0.335
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.666 0.333
J18.2 Hypostatic pneumonia, unspecified
0.000 0.669 0.331
J14 Pneumonia due to Haemophilus influenzae
0.000 0.669 0.331
I78.1 Naevus, nonneoplastic
0.000 0.670 0.330
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.670 0.330
I62.1 Nontraumatic extradural haemorrhage
0.000 0.672 0.328
I05.1 Rheumatic mitral insufficiency
0.000 0.675 0.325
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.682 0.318
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.684 0.316
I09.8 Other specified rheumatic heart diseases
0.000 0.690 0.310
I09.2 Chronic rheumatic pericarditis
0.000 0.690 0.310
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.690 0.310
I09.0 Rheumatic myocarditis
0.000 0.690 0.310
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.693 0.307
I07.9 Tricuspid valve disease, unspecified
0.000 0.698 0.302
I07.8 Other tricuspid valve diseases
0.000 0.698 0.302
I07.2 Tricuspid stenosis with insufficiency
0.000 0.698 0.302
I07.0 Tricuspid stenosis
0.000 0.698 0.302
J18.8 Other pneumonia, organism unspecified
0.000 0.699 0.301
J18.9 Pneumonia, unspecified
0.000 0.708 0.292
I05.0 Mitral stenosis
0.000 0.713 0.287
J21 Acute bronchiolitis
0.000 0.713 0.287
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.719 0.281
J16.0 Chlamydial pneumonia
0.000 0.719 0.281
J15.2 Pneumonia due to staphylococcus
0.000 0.721 0.278
I05.8 Other mitral valve diseases
0.000 0.723 0.277
J15.8 Other bacterial pneumonia
0.000 0.725 0.275
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.726 0.273
J45 Asthma
0.000 0.726 0.273
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.727 0.273
J15.5 Pneumonia due to Escherichia coli
0.000 0.728 0.272
J20 Acute bronchitis
0.000 0.728 0.271
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.733 0.266
J15.4 Pneumonia due to other streptococci
0.000 0.734 0.266
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.736 0.264
J15.3 Pneumonia due to streptococcus, group B
0.000 0.740 0.260
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.744 0.256
I06.8 Other rheumatic aortic valve diseases
0.000 0.744 0.256
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.744 0.256
I06.1 Rheumatic aortic insufficiency
0.000 0.744 0.256
J15.9 Bacterial pneumonia, unspecified
0.000 0.744 0.256
I05.2 Mitral stenosis with insufficiency
0.000 0.748 0.252
J12.8 Other viral pneumonia
0.000 0.748 0.251
J12.3 Human metapneumovirus pneumonia
0.000 0.748 0.251
J12.2 Parainfluenza virus pneumonia
0.000 0.748 0.251
J12.1 Respiratory syncytial virus pneumonia
0.000 0.748 0.251
J12.0 Adenoviral pneumonia
0.000 0.748 0.251
J00-J06 Acute upper respiratory infections
0.000 0.749 0.251
I10-I15 Hypertensive diseases
0.000 0.752 0.248
J94.2 Haemothorax
0.001 0.755 0.245
J11 Influenza, virus not identified
0.001 0.757 0.242
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.760 0.240
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.763 0.237
J84 Other interstitial pulmonary diseases
0.000 0.766 0.234
I63 Cerebral infarction
0.000 0.773 0.227
I06.0 Rheumatic aortic stenosis
0.000 0.773 0.226
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.773 0.226
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.773 0.226
I99 Other and unspecified disorders of circulatory system
0.000 0.773 0.226
J17.3 Pneumonia in parasitic diseases
0.000 0.776 0.224
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.779 0.221
J15.1 Pneumonia due to Pseudomonas
0.000 0.779 0.221
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.780 0.220
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.782 0.218
I05.9 Mitral valve disease, unspecified
0.000 0.787 0.212
J12.9 Viral pneumonia, unspecified
0.000 0.790 0.210
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.791 0.209
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.794 0.205
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.794 0.205
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.794 0.205
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.795 0.204
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.798 0.202
J21.9 Acute bronchiolitis, unspecified
0.000 0.799 0.201
Z72.0 Tobacco use
0.000 0.800 0.200
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.803 0.197
J45.8 Mixed asthma
0.000 0.804 0.196
J45.1 Nonallergic asthma
0.000 0.804 0.196
Z72.1 Alcohol use
0.000 0.804 0.196
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.804 0.196
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.804 0.196
I98.0 Cardiovascular syphilis
0.000 0.804 0.196
Z72 Problems related to lifestyle
0.000 0.805 0.195
J20.7 Acute bronchitis due to echovirus
0.000 0.805 0.195
J20.6 Acute bronchitis due to rhinovirus
0.000 0.805 0.195
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.805 0.195
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.805 0.195
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.805 0.195
J20.2 Acute bronchitis due to streptococcus
0.000 0.805 0.195
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.805 0.195
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.805 0.195
J17.2 Pneumonia in mycoses
0.000 0.806 0.194
J20.8 Acute bronchitis due to other specified organisms
0.000 0.806 0.193
F17.1 Harmful use
0.000 0.809 0.191
J00 Acute nasopharyngitis [common cold]
0.000 0.810 0.190
I95 Hypotension
0.000 0.813 0.187
I15 Secondary hypertension
0.000 0.817 0.183
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.820 0.180
I13 Hypertensive heart and renal disease
0.000 0.822 0.178
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.823 0.177
J20.9 Acute bronchitis, unspecified
0.000 0.824 0.176
J11.8 Influenza with other manifestations, virus not identified
0.001 0.826 0.174
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.832 0.168
J84.0 Alveolar and parietoalveolar conditions
0.000 0.832 0.168
J84.8 Other specified interstitial pulmonary diseases
0.000 0.834 0.165
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.834 0.165
I95.1 Orthostatic hypotension
0.000 0.835 0.165
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.837 0.163
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.837 0.163
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.837 0.163
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.839 0.161
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.841 0.159
I97.0 Postcardiotomy syndrome
0.000 0.841 0.159
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.841 0.158
J01 Acute sinusitis
0.000 0.844 0.156
Z72.2 Drug use
0.000 0.844 0.156
I65.1 Occlusion and stenosis of basilar artery
0.001 0.844 0.155
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.847 0.153
J02 Acute pharyngitis
0.000 0.850 0.150
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.850 0.150
I95.8 Other hypotension
0.000 0.850 0.150
I15.1 Hypertension secondary to other renal disorders
0.000 0.853 0.147
I12 Hypertensive renal disease
0.000 0.854 0.146
J04 Acute laryngitis and tracheitis
0.000 0.855 0.145
J47 Bronchiectasis
0.000 0.856 0.144
J03 Acute tonsillitis
0.000 0.857 0.143
F17.2 Dependence syndrome
0.000 0.857 0.143
Z72.6 Gambling and betting
0.000 0.860 0.140
Z72.5 High-risk sexual behaviour
0.000 0.860 0.140
Z72.3 Lack of physical exercise
0.000 0.860 0.140
Z72.4 Inappropriate diet and eating habits
0.000 0.860 0.140
I15.9 Seconday hypertension, unspecified
0.000 0.860 0.140
Z72.8 Other problems related to lifestyle
0.000 0.862 0.138
J11.0 Influenza with pneumonia, virus not identified
0.001 0.862 0.137
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.862 0.138
I65.2 Occlusion and stenosis of carotid artery
0.000 0.863 0.137
I11 Hypertensive heart disease
0.000 0.865 0.135
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.866 0.134
I87 Other disorders of veins
0.000 0.869 0.131
I15.8 Other secondary hypertension
0.000 0.869 0.131
I15.2 Hypertension secondary to endocrine disorders
0.000 0.869 0.131
J05.0 Acute obstructive laryngitis [croup]
0.000 0.871 0.129
J05.1 Acute epiglottitis
0.000 0.871 0.129
Z72.9 Problem related to lifestyle, unspecified
0.000 0.872 0.128
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.872 0.127
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.872 0.127
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.872 0.127
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.872 0.127
J45.0 Predominantly allergic asthma
0.000 0.874 0.126
J18.0 Bronchopneumonia, unspecified
0.000 0.875 0.125
I81 Portal vein thrombosis
0.000 0.876 0.124
I97.1 Other functional disturbances following cardiac surgery
0.000 0.876 0.123
I88 Nonspecific lymphadenitis
0.000 0.877 0.123
I85 Oesophageal varices
0.000 0.880 0.120
I87.1 Compression of vein
0.000 0.881 0.118
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.885 0.115
I80 Phlebitis and thrombophlebitis
0.000 0.886 0.114
J01.0 Acute maxillary sinusitis
0.000 0.887 0.113
J01.8 Other acute sinusitis
0.000 0.888 0.112
J01.4 Acute pansinusitis
0.000 0.888 0.112
J01.3 Acute sphenoidal sinusitis
0.000 0.888 0.112
J01.1 Acute frontal sinusitis
0.000 0.888 0.112
J02.0 Streptococcal pharyngitis
0.000 0.889 0.111
J81 Pulmonary oedema
0.000 0.889 0.111
I95.0 Idiopathic hypotension
0.000 0.889 0.111
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.892 0.108
F17.8 Other mental and behavioural disorders
0.000 0.892 0.107
F17.7 Residual and late-onset psychotic disorder
0.000 0.892 0.107
F17.6 Amnesic syndrome
0.000 0.892 0.107
F17.5 Psychotic disorder
0.000 0.892 0.107
F17.4 Withdrawal state with delirium
0.000 0.892 0.107
F17.3 Withdrawal state
0.000 0.892 0.107
J01.2 Acute ethmoidal sinusitis
0.000 0.894 0.106
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.894 0.106
I85.0 Oesophageal varices with bleeding
0.000 0.894 0.105
I87.8 Other specified disorders of veins
0.000 0.895 0.105
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.895 0.105
J04.2 Acute laryngotracheitis
0.000 0.896 0.104
I12.9 Hypertensive renal disease without renal failure
0.000 0.896 0.104
I15.0 Renovascular hypertension
0.000 0.896 0.103
E11 Non-insulin-dependent diabetes mellitus
0.000 0.897 0.103
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.897 0.103
J03.0 Streptococcal tonsillitis
0.000 0.897 0.103
F17.9 Unspecified mental and behavioural disorder
0.000 0.897 0.103
E11.3 With ophthalmic complications
0.000 0.898 0.102
F17.0 Acute intoxication
0.000 0.899 0.101
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.899 0.100
J04.1 Acute tracheitis
0.000 0.899 0.101
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.900 0.099
I87.9 Disorder of vein, unspecified
0.000 0.906 0.094
I87.0 Postphlebitic syndrome
0.000 0.906 0.094
J01.9 Acute sinusitis, unspecified
0.000 0.906 0.094
E11.0 With coma
0.000 0.907 0.093
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.907 0.093
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.907 0.091

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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