TreeWAS – Variant ID: rs12449000

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C43.5 Malignant melanoma of trunk	0.573	0.427	0.000
C43 Malignant melanoma of skin	0.570	0.430	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.552	0.448	0.000
C43.4 Malignant melanoma of scalp and neck	0.540	0.460	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.487	0.513	0.000
C44.6 Skin of upper limb, including shoulder	0.470	0.530	0.000
C43.9 Malignant melanoma of skin, unspecified	0.455	0.545	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.442	0.558	0.000
C44 Other malignant neoplasms of skin	0.416	0.584	0.000
C43.8 Overlapping malignant melanoma of skin	0.409	0.591	0.000
C43.0 Malignant melanoma of lip	0.409	0.591	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.357	0.643	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.332	0.668	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.302	0.698	0.000
C44.8 Overlapping lesion of skin	0.299	0.701	0.000
C44.4 Skin of scalp and neck	0.286	0.714	0.000
C44.3 Skin of other and unspecified parts of face	0.255	0.745	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.253	0.747	0.000
C44.0 Skin of lip	0.240	0.760	0.000
C44.5 Skin of trunk	0.237	0.763	0.000
C44.2 Skin of ear and external auricular canal	0.123	0.877	0.000
C44.7 Skin of lower limb, including hip	0.069	0.931	0.000
C44.1 Skin of eyelid, including canthus	0.067	0.933	0.000
J33.9 Nasal polyp, unspecified	0.000	0.959	0.041
C64 Malignant neoplasm of kidney, except renal pelvis	0.027	0.973	0.000
L85.8 Other specified epidermal thickening	0.020	0.980	0.000
L85.9 Epidermal thickening, unspecified	0.019	0.981	0.000
L85 Other epidermal thickening	0.018	0.982	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.014	0.986	0.000
L85.3 Xerosis cutis	0.013	0.987	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.013	0.987	0.000
L85.0 Acquired ichthyosis	0.013	0.987	0.000
H61.2 Impacted cerumen	0.000	0.987	0.013
K59.8 Other specified functional intestinal disorders	0.000	0.988	0.012
S92.30 Fracture of metatarsal bone (closed)	0.000	0.991	0.009
H43.8 Other disorders of vitreous body	0.000	0.991	0.009
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.008	0.992	0.000
H61 Other disorders of external ear	0.000	0.992	0.008
G31.9 Degenerative disease of nervous system, unspecified	0.008	0.992	0.000
H61.1 Non-infective disorders of pinna	0.000	0.992	0.008
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.993	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.993	0.007
H61.8 Other specified disorders of external ear	0.000	0.993	0.007
C64-C68 Malignant neoplasms of urinary tract	0.007	0.993	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.006	0.994	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.994	0.006
H61.3 Acquired stenosis of external ear canal	0.000	0.994	0.006
C66 Malignant neoplasm of ureter	0.006	0.994	0.000
G31.2 Degeneration of nervous system due to alcohol	0.006	0.994	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T21.3 Burn of third degree of trunk	0.000	0.995	0.005
G31.8 Other specified degenerative diseases of nervous system	0.005	0.995	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.005	0.995	0.000
T21 Burn and corrosion of trunk	0.000	0.995	0.005
J98.4 Other disorders of lung	0.000	0.995	0.005
G31.0 Circumscribed brain atrophy	0.005	0.995	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.005	0.995	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.005	0.995	0.000
C65 Malignant neoplasm of renal pelvis	0.005	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
G31.1 Senile degeneration of brain, not elsewhere classified	0.005	0.995	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.005	0.995	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.996	0.004
C68.9 Urinary organ, unspecified	0.004	0.996	0.000
T21.2 Burn of second degree of trunk	0.000	0.996	0.004
M79.62 Pain in limb (Upper arm)	0.000	0.996	0.004
S92.3 Fracture of metatarsal bone	0.000	0.996	0.004
T23 Burn and corrosion of wrist and hand	0.000	0.996	0.004
T21.1 Burn of first degree of trunk	0.000	0.996	0.004
M70.6 Trochanteric bursitis	0.000	0.996	0.004
T21.0 Burn of unspecified degree of trunk	0.000	0.996	0.004
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
H43 Disorders of vitreous body	0.000	0.996	0.004
C68.8 Overlapping lesion of urinary organs	0.004	0.996	0.000
C68.1 Paraurethral glands	0.004	0.996	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.996	0.004
T21.7 Corrosion of third degree of trunk	0.000	0.996	0.004
T21.6 Corrosion of second degree of trunk	0.000	0.996	0.004
T21.5 Corrosion of first degree of trunk	0.000	0.996	0.004
T21.4 Corrosion of unspecified degree of trunk	0.000	0.996	0.004
T23.2 Burn of second degree of wrist and hand	0.000	0.996	0.004
M21.6 Other acquired deformities of ankle and foot	0.004	0.996	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T25 Burn and corrosion of ankle and foot	0.000	0.996	0.004
H61.0 Perichondritis of external ear	0.000	0.996	0.004
H43.3 Other vitreous opacities	0.000	0.996	0.004
T20 Burn and corrosion of head and neck	0.000	0.996	0.004
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.996	0.004
T25.3 Burn of third degree of ankle and foot	0.000	0.997	0.003
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
S42.20 Fracture of upper end of humerus (closed)	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
J33 Nasal polyp	0.000	0.997	0.003
T20.2 Burn of second degree of head and neck	0.000	0.997	0.003
O75.8 Other specified complications of labour and delivery	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.997	0.003
T23.6 Corrosion of second degree of wrist and hand	0.000	0.997	0.003
T23.5 Corrosion of first degree of wrist and hand	0.000	0.997	0.003
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.997	0.003
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.003	0.997	0.000
C68.0 Urethra	0.003	0.997	0.000
M70.68 Trochanteric bursitis-Other	0.000	0.997	0.003
M70.67 Trochanteric bursitis-Ankle/Foot	0.000	0.997	0.003
M70.66 Trochanteric bursitis-Lower Leg	0.000	0.997	0.003
M70.64 Trochanteric bursitis-Hand	0.000	0.997	0.003
M70.63 Trochanteric bursitis-Forearm	0.000	0.997	0.003
M70.62 Trochanteric bursitis-Upper arm	0.000	0.997	0.003
M70.61 Trochanteric bursitis-Shldr region	0.000	0.997	0.003
M70.60 Trochanteric bursitis-Mult sites	0.000	0.997	0.003
C18.7 Sigmoid colon	0.000	0.997	0.003
T68 Hypothermia	0.003	0.997	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.997	0.003
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
H43.2 Crystalline deposits in vitreous body	0.000	0.997	0.003
H43.0 Vitreous prolapse	0.000	0.997	0.003
T66 Unspecified effects of radiation	0.003	0.997	0.000
T25.2 Burn of second degree of ankle and foot	0.000	0.997	0.003
T23.1 Burn of first degree of wrist and hand	0.000	0.997	0.003
I24.8 Other forms of acute ischaemic heart disease	0.000	0.997	0.003
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.997	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.997	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.997	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.997	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.997	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.997	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.997	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.997	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.997	0.000
M70.69 Trochanteric bursitis-Site unspec	0.000	0.997	0.003
T25.7 Corrosion of third degree of ankle and foot	0.000	0.997	0.003
T25.6 Corrosion of second degree of ankle and foot	0.000	0.997	0.003
T25.5 Corrosion of first degree of ankle and foot	0.000	0.997	0.003
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.997	0.003
T25.1 Burn of first degree of ankle and foot	0.000	0.997	0.003
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
T78 Adverse effects, not elsewhere classified	0.003	0.997	0.000
K12.2 Cellulitis and abscess of mouth	0.003	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.997	0.003
T20.7 Corrosion of third degree of head and neck	0.000	0.997	0.003
T20.6 Corrosion of second degree of head and neck	0.000	0.997	0.003
T20.5 Corrosion of first degree of head and neck	0.000	0.997	0.003
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.997	0.003
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.997	0.003
H43.9 Disorder of vitreous body, unspecified	0.000	0.997	0.003
J34.2 Deviated nasal septum	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.003	0.997	0.000
D23.7 Skin of lower limb, including hip	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.003
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
O75.0 Maternal distress during labour and delivery	0.000	0.997	0.003
K52.0 Gastro-enteritis and colitis due to radiation	0.003	0.997	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.000	0.997	0.003
Z50.2 Alcohol rehabilitation	0.000	0.997	0.003
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.997	0.003
G30-G32 Other degenerative diseases of the nervous system	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
T20.3 Burn of third degree of head and neck	0.000	0.997	0.002
J33.1 Polypoid sinus degeneration	0.000	0.997	0.003
M23.8 Other internal derangements of knee	0.003	0.997	0.000
M76.6 Achilles tendinitis	0.003	0.997	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.997	0.003
T70.3 Caisson disease [decompression sickness]	0.003	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.000	0.997	0.003
Z73.3 Stress, not elsewhere classified	0.003	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.997	0.003
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.997	0.002
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.997	0.002
H60-H62 Diseases of external ear	0.000	0.997	0.003
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.997	0.002
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.997	0.000
M70.4 Prepatellar bursitis	0.000	0.997	0.002
T20.1 Burn of first degree of head and neck	0.000	0.998	0.002
M70.2 Olecranon bursitis	0.000	0.998	0.002
D22.7 Melanocytic naevi of lower limb, including hip	0.002	0.998	0.000
M70.3 Other bursitis of elbow	0.000	0.998	0.002
T74 Maltreatment syndromes	0.002	0.998	0.000
T73 Effects of other deprivation	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
T71 Asphyxiation	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
O41.0 Oligohydramnios	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.002	0.998	0.000
X51.9 Unspecified place	0.000	0.998	0.002
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
O82 Single delivery by Caesarean section	0.000	0.998	0.002
E87.7 Fluid overload	0.000	0.998	0.002
O82.1 Delivery by emergency Caesarean section	0.000	0.998	0.002
M70.7 Other bursitis of hip	0.000	0.998	0.002
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.998	0.002
G30 Alzheimer's disease	0.002	0.998	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.998	0.002
O75.3 Other infection during labour	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.002	0.998	0.000
T70.8 Other effects of air pressure and water pressure	0.002	0.998	0.000
T70.4 Effects of high-pressure fluids	0.002	0.998	0.000
T70.2 Other and unspecified effects of high altitude	0.002	0.998	0.000
T70.1 Sinus barotrauma	0.002	0.998	0.000
T70.0 Otitic barotrauma	0.002	0.998	0.000
T75 Effects of other external causes	0.002	0.998	0.000
M70.32 Other bursitis of elbow-Upper arm	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.000	0.998	0.002
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.000	0.998	0.002
M70.1 Bursitis of hand	0.000	0.998	0.002
M70.0 Chronic crepitant synovitis of hand and wrist	0.000	0.998	0.002
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
O75.9 Complication of labour and delivery, unspecified	0.000	0.998	0.002
O75.4 Other complications of obstetric surgery and procedures	0.000	0.998	0.002
O75.1 Shock during or following labour and delivery	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
K63.8 Other specified diseases of intestine	0.000	0.998	0.002
T78.3 Angioneurotic oedema	0.002	0.998	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.002	0.998	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M76.69 Achilles tendinitis-Site unspec	0.002	0.998	0.000
M76.68 Achilles tendinitis-Other	0.002	0.998	0.000
M76.65 Achilles tendinitis-Pelvic/Thigh	0.002	0.998	0.000
M76.64 Achilles tendinitis-Hand	0.002	0.998	0.000
M76.63 Achilles tendinitis-Forearm	0.002	0.998	0.000
M76.62 Achilles tendinitis-Upper arm	0.002	0.998	0.000
M76.61 Achilles tendinitis-Shldr region	0.002	0.998	0.000
M76.60 Achilles tendinitis (Multiple sites)	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
O82.9 Delivery by Caesarean section, unspecified	0.000	0.998	0.002
T78.0 Anaphylactic shock due to adverse food reaction	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.000	0.998	0.002
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.998	0.002
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M70.49 Prepatellar bursitis-Site unspec	0.000	0.998	0.002
M70.48 Prepatellar bursitis-Other	0.000	0.998	0.002
M70.47 Prepatellar bursitis-Ankle/Foot	0.000	0.998	0.002
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.000	0.998	0.002
M70.44 Prepatellar bursitis-Hand	0.000	0.998	0.002
M70.43 Prepatellar bursitis-Forearm	0.000	0.998	0.002
M70.42 Prepatellar bursitis-Upper arm	0.000	0.998	0.002
M70.41 Prepatellar bursitis-Shldr region	0.000	0.998	0.002
M70.40 Prepatellar bursitis-Mult sites	0.000	0.998	0.002
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
M70.29 Olecranon bursitis-Site unspec	0.000	0.998	0.002
M70.28 Olecranon bursitis-Other	0.000	0.998	0.002
M70.27 Olecranon bursitis-Ankle/Foot	0.000	0.998	0.002
M70.26 Olecranon bursitis-Lower Leg	0.000	0.998	0.002
M70.25 Olecranon bursitis-Pelvic/Thigh	0.000	0.998	0.002
M70.24 Olecranon bursitis-Hand	0.000	0.998	0.002
M70.23 Olecranon bursitis-Forearm	0.000	0.998	0.002
M70.21 Olecranon bursitis-Shldr region	0.000	0.998	0.002
M70.20 Olecranon bursitis-Mult sites	0.000	0.998	0.002
M70.39 Other bursitis of elbow-Site unspec	0.000	0.998	0.002
M70.38 Other bursitis of elbow-Other	0.000	0.998	0.002
M70.37 Other bursitis of elbow-Ankle/Foot	0.000	0.998	0.002
M70.36 Other bursitis of elbow-Lower Leg	0.000	0.998	0.002
M70.35 Other bursitis of elbow-Pelvic/Thigh	0.000	0.998	0.002
M70.34 Other bursitis of elbow-Hand	0.000	0.998	0.002
M70.33 Other bursitis of elbow-Forearm	0.000	0.998	0.002
M70.31 Other bursitis of elbow-Shldr region	0.000	0.998	0.002
M70.30 Other bursitis of elbow-Mult sites	0.000	0.998	0.002
T67.9 Effects of heat and light, unspecified	0.002	0.998	0.000
T67.8 Other effects of heat and light	0.002	0.998	0.000
T67.7 Heat oedema	0.002	0.998	0.000
T67.6 Heat fatigue, transient	0.002	0.998	0.000
T67.5 Heat exhaustion, unspecified	0.002	0.998	0.000
T67.4 Heat exhaustion due to salt depletion	0.002	0.998	0.000
T67.3 Heat exhaustion, anhydrotic	0.002	0.998	0.000
T67.2 Heat cramp	0.002	0.998	0.000
T67.1 Heat syncope	0.002	0.998	0.000
T67.0 Heatstroke and sunstroke	0.002	0.998	0.000
T69.9 Effect of reduced temperature, unspecified	0.002	0.998	0.000
T69.8 Other specified effects of reduced temperature	0.002	0.998	0.000
T69.1 Chilblains	0.002	0.998	0.000
T69.0 Immersion hand and foot	0.002	0.998	0.000
T73.9 Effect of deprivation, unspecified	0.002	0.998	0.000
T73.8 Other effects of deprivation	0.002	0.998	0.000
T73.3 Exhaustion due to excessive exertion	0.002	0.998	0.000
T73.2 Exhaustion due to exposure	0.002	0.998	0.000
T73.1 Effects of thirst	0.002	0.998	0.000
T73.0 Effects of hunger	0.002	0.998	0.000
T74.9 Maltreatment syndrome, unspecified	0.002	0.998	0.000
T74.8 Other maltreatment syndromes	0.002	0.998	0.000
T74.3 Psychological abuse	0.002	0.998	0.000
T74.2 Sexual abuse	0.002	0.998	0.000
T74.1 Physical abuse	0.002	0.998	0.000
T74.0 Neglect or abandonment	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.998	0.002
M70.75 Other bursitis of hip-Pelvic/Thigh	0.000	0.998	0.002
M70.5 Other bursitis of knee	0.000	0.998	0.002
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.998	0.002
O82.2 Delivery by Caesarean hysterectomy	0.000	0.998	0.002
M70.79 Other bursitis of hip-Site unspec	0.000	0.998	0.002
M70.78 Other bursitis of hip-Other	0.000	0.998	0.002
M70.77 Other bursitis of hip-Ankle/Foot	0.000	0.998	0.002
M70.76 Other bursitis of hip-Lower Leg	0.000	0.998	0.002
M70.74 Other bursitis of hip-Hand	0.000	0.998	0.002
M70.73 Other bursitis of hip-Forearm	0.000	0.998	0.002
M70.72 Other bursitis of hip-Upper arm	0.000	0.998	0.002
M70.71 Other bursitis of hip-Shldr region	0.000	0.998	0.002
M70.70 Other bursitis of hip-Mult sites	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
Y60.4 During endoscopic examination	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
T75.8 Other specified effects of external causes	0.002	0.998	0.000
T75.3 Motion sickness	0.002	0.998	0.000
T75.2 Effects of vibration	0.002	0.998	0.000
T75.0 Effects of lightning	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
M70.09 Chronic crepitant synovitis of hand and wrist-Site unspec	0.000	0.998	0.002
M70.08 Chronic crepitant synovitis of hand and wrist-Other	0.000	0.998	0.002
M70.07 Chronic crepitant synovitis of hand and wrist-Ankle/Foot	0.000	0.998	0.002
M70.06 Chronic crepitant synovitis of hand and wrist-Lower Leg	0.000	0.998	0.002
M70.05 Chronic crepitant synovitis of hand and wrist-Pelvic/Thigh	0.000	0.998	0.002
M70.04 Chronic crepitant synovitis of hand and wrist (Hand)	0.000	0.998	0.002
M70.03 Chronic crepitant synovitis of hand and wrist (Forearm)	0.000	0.998	0.002
M70.02 Chronic crepitant synovitis of hand and wrist-Upper arm	0.000	0.998	0.002
M70.01 Chronic crepitant synovitis of hand and wrist-Shldr region	0.000	0.998	0.002
M70.00 Chronic crepitant synovitis of hand and wrist (Multiple sites)	0.000	0.998	0.002
M70.19 Bursitis of hand-Site unspec	0.000	0.998	0.002
M70.18 Bursitis of hand-Other	0.000	0.998	0.002
M70.17 Bursitis of hand-Ankle/Foot	0.000	0.998	0.002
M70.16 Bursitis of hand-Lower Leg	0.000	0.998	0.002
M70.15 Bursitis of hand-Pelvic/Thigh	0.000	0.998	0.002
M70.14 Bursitis of hand-Hand	0.000	0.998	0.002
M70.13 Bursitis of hand-Forearm	0.000	0.998	0.002
M70.12 Bursitis of hand-Upper arm	0.000	0.998	0.002
M70.11 Bursitis of hand-Shldr region	0.000	0.998	0.002
M70.10 Bursitis of hand-Mult sites	0.000	0.998	0.002
M70.89 Other soft tissue disorders related to use, overuse and pressure (Site unspecified)	0.000	0.998	0.002
M70.88 Other soft tissue disorders related to use, overuse and pressure (Other)	0.000	0.998	0.002
M70.87 Other soft tissue disorders related to use, overuse and pressure (Ankle and foot)	0.000	0.998	0.002
M70.86 Other soft tissue disorders related to use, overuse and pressure (Lower leg)	0.000	0.998	0.002
M70.85 Other soft tissue disorders related to use, overuse and pressure (Pelvic region and thigh)	0.000	0.998	0.002
M70.84 Other soft tissue disorders related to use, overuse and pressure (Hand)	0.000	0.998	0.002
M70.83 Other soft tissue disorders related to use, overuse and pressure (Forearm)	0.000	0.998	0.002
M70.82 Other soft tissue disorders related to use, overuse and pressure (Upper arm)	0.000	0.998	0.002
M70.81 Other soft tissue disorders related to use, overuse and pressure (Shoulder region)	0.000	0.998	0.002
M70.80 Other soft tissue disorders related to use, overuse and pressure (Multiple sites)	0.000	0.998	0.002
M70.99 Unspecified soft tissue disorder related to use, overuse and pressure (Site unspecified)	0.000	0.998	0.002
M70.98 Unspecified soft tissue disorder related to use, overuse and pressure (Other)	0.000	0.998	0.002
M70.97 Unspecified soft tissue disorder related to use, overuse and pressure (Ankle and foot)	0.000	0.998	0.002
M70.96 Unspecified soft tissue disorder related to use, overuse and pressure (Lower leg)	0.000	0.998	0.002
M70.95 Unspecified soft tissue disorder related to use, overuse and pressure (Pelvic region and thigh)	0.000	0.998	0.002
M70.94 Unspecified soft tissue disorder related to use, overuse and pressure (Hand)	0.000	0.998	0.002
M70.93 Unspecified soft tissue disorder related to use, overuse and pressure (Forearm)	0.000	0.998	0.002
M70.92 Unspecified soft tissue disorder related to use, overuse and pressure (Upper arm)	0.000	0.998	0.002
M70.91 Unspecified soft tissue disorder related to use, overuse and pressure (Shoulder region)	0.000	0.998	0.002
M70.90 Unspecified soft tissue disorder related to use, overuse and pressure (Multiple sites)	0.000	0.998	0.002
M76.66 Achilles tendinitis (Lower leg)	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
T75.1 Drowning and nonfatal submersion	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.000	0.998	0.002
K82.1 Hydrops of gallbladder	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
G30.8 Other Alzheimer's disease	0.002	0.998	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.001	0.998	0.000
T75.4 Effects of electric current	0.002	0.998	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.002	0.998	0.000
M70.59 Other bursitis of knee-Site unspec	0.000	0.998	0.001
M70.58 Other bursitis of knee-Other	0.000	0.998	0.001
M70.57 Other bursitis of knee-Ankle/Foot	0.000	0.998	0.001
M70.55 Other bursitis of knee-Pelvic/Thigh	0.000	0.998	0.001
M70.54 Other bursitis of knee-Hand	0.000	0.998	0.001
M70.53 Other bursitis of knee-Forearm	0.000	0.998	0.001
M70.52 Other bursitis of knee-Upper arm	0.000	0.998	0.001
M70.51 Other bursitis of knee-Shldr region	0.000	0.998	0.001
M70.50 Other bursitis of knee-Mult sites	0.000	0.998	0.001
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.998	0.001
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.998	0.001
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
H62.2 Otitis externa in mycoses	0.000	0.998	0.001
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.998	0.001
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.001
L57.0 Actinic keratosis	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
C71.6 Cerebellum	0.001	0.998	0.000
C71.5 Cerebral ventricle	0.001	0.998	0.000
D26.0 Cervix uteri	0.000	0.998	0.002
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
H43.1 Vitreous haemorrhage	0.000	0.998	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.998	0.002
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.998	0.001
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.000	0.998	0.002
C71.7 Brain stem	0.001	0.998	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.001	0.998	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
C71.3 Parietal lobe	0.001	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.001	0.998	0.000
R09.1 Pleurisy	0.000	0.998	0.002
D04.9 Skin, unspecified	0.001	0.998	0.000
D06.9 Cervix, unspecified	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
R44.1 Visual hallucinations	0.002	0.998	0.000
C71.4 Occipital lobe	0.001	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.001
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.001	0.998	0.000
K85.1 Biliary acute pancreatitis	0.000	0.999	0.001
Z73.5 Social role conflict, not elsewhere classified	0.001	0.999	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.001	0.999	0.000
Z73.2 Lack of relaxation and leisure	0.001	0.999	0.000
Z73.1 Accentuation of personality traits	0.001	0.999	0.000
Z73.0 Burn-out	0.001	0.999	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.999	0.001
M70.56 Other bursitis of knee-Lower Leg	0.000	0.999	0.001
H65.2 Chronic serous otitis media	0.000	0.999	0.001
M87.8 Other osteonecrosis	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
R09.3 Abnormal sputum	0.000	0.999	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.001	0.999	0.000
K11.8 Other diseases of salivary glands	0.000	0.999	0.001
Q63.0 Accessory kidney	0.000	0.999	0.001
M87 Osteonecrosis	0.001	0.999	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.999	0.001
Z73.6 Limitation of activities due to disability	0.001	0.999	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.999	0.001
C81.9 Hodgkin's disease, unspecified	0.000	0.999	0.001
H72.0 Central perforation of tympanic membrane	0.000	0.999	0.001
Z35.8 Supervision of other high-risk pregnancies	0.000	0.999	0.001
K50 Crohn's disease [regional enteritis]	0.000	0.999	0.001
H60.0 Abscess of external ear	0.000	0.999	0.001
K56.6 Other and unspecified intestinal obstruction	0.000	0.999	0.001
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.999	0.001
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.999	0.001
W13.9 Unspecified place	0.001	0.999	0.000
Z73.8 Other problems related to life-management difficulty	0.001	0.999	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
M87.86 Other osteonecrosis (Lower leg)	0.001	0.999	0.000
J32.8 Other chronic sinusitis	0.000	0.999	0.001
D04 Carcinoma in situ of skin	0.001	0.999	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.001	0.999	0.000
M76 Enthesopathies of lower limb, excluding foot	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.001	0.999	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.999	0.001
L94.0 Localised scleroderma [morphea]	0.000	0.999	0.001
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.999	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.999	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.999	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.999	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.001	0.999	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.999	0.001
H60.2 Malignant otitis externa	0.000	0.999	0.001
K52.1 Toxic gastro-enteritis and colitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations