TreeWAS – Variant ID: rs12463617

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	1.000	0.000	0.000
E66 Obesity	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001	0.000
E11.9 Without complications	0.998	0.002	0.000
E66.8 Other obesity	0.998	0.002	0.000
E11.4 With neurological complications	0.990	0.010	0.000
E10-E14 Diabetes mellitus	0.967	0.033	0.000
E65-E68 Obesity and other hyperalimentation	0.965	0.035	0.000
E11.2 With renal complications	0.962	0.038	0.000
E11.3 With ophthalmic complications	0.927	0.073	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.921	0.079	0.000
E11.5 With peripheral circulatory complications	0.822	0.178	0.000
E10 Insulin-dependent diabetes mellitus	0.817	0.183	0.000
E65 Localised adiposity	0.813	0.187	0.000
E66.0 Obesity due to excess calories	0.796	0.204	0.000
E11.8 With unspecified complications	0.794	0.206	0.000
E14 Unspecified diabetes mellitus	0.779	0.221	0.000
E11.7 With multiple complications	0.752	0.248	0.000
E66.1 Drug-induced obesity	0.717	0.283	0.000
E10.9 Without complications	0.715	0.285	0.000
E12 Malnutrition-related diabetes mellitus	0.694	0.306	0.000
E67 Other hyperalimentation	0.692	0.308	0.000
E68 Sequelae of hyperalimentation	0.692	0.308	0.000
E14.3 With ophthalmic complications	0.676	0.324	0.000
E11.1 With ketoacidosis	0.665	0.335	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.659	0.341	0.000
E50-E64 Other nutritional deficiencies	0.658	0.342	0.000
E10.0 With coma	0.648	0.352	0.000
E10.8 With unspecified complications	0.647	0.353	0.000
E11.6 With other specified complications	0.642	0.358	0.000
E10.7 With multiple complications	0.641	0.358	0.000
E10.4 With neurological complications	0.639	0.361	0.000
E10.2 With renal complications	0.635	0.365	0.000
E13 Other specified diabetes mellitus	0.613	0.386	0.000
E61 Deficiency of other nutrient elements	0.608	0.392	0.000
E14.6 With other specified complications	0.603	0.396	0.000
E14.1 With ketoacidosis	0.596	0.404	0.000
E11.0 With coma	0.589	0.411	0.000
E61.1 Iron deficiency	0.575	0.425	0.000
E10.5 With peripheral circulatory complications	0.563	0.437	0.000
E14.8 With unspecified complications	0.560	0.440	0.000
E14.7 With multiple complications	0.559	0.441	0.000
E10.6 With other specified complications	0.557	0.442	0.000
E14.5 With peripheral circulatory complications	0.553	0.447	0.000
E14.0 With coma	0.542	0.458	0.000
E14.2 Withrenal complications	0.539	0.461	0.000
E58 Dietary calcium deficiency	0.504	0.496	0.000
E12.9 Without complications	0.497	0.503	0.000
E12.8 With unspecified complications	0.497	0.503	0.000
E12.7 With multiple complications	0.497	0.503	0.000
E12.6 With other specified complications	0.497	0.503	0.000
E12.5 With peripheral circulatory complications	0.497	0.503	0.000
E12.4 With neurological complications	0.497	0.503	0.000
E12.3 With ophthalmic complications	0.497	0.503	0.000
E12.2 With renal complications	0.497	0.503	0.000
E12.1 With ketoacidosis	0.497	0.503	0.000
E12.0 With coma	0.497	0.503	0.000
E67.8 Other specified hyperalimentation	0.496	0.504	0.000
E67.3 Hypervitaminosis D	0.496	0.504	0.000
E67.2 Megavitamin-B6 syndrome	0.496	0.504	0.000
E67.1 Hypercarotenaemia	0.496	0.504	0.000
E67.0 Hypervitaminosis A	0.496	0.504	0.000
E14.4 With neurological complications	0.496	0.504	0.000
E14.9 Without complications	0.495	0.505	0.000
E40-E46 Malnutrition	0.493	0.507	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.490	0.510	0.000
E54 Ascorbic acid deficiency	0.488	0.511	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.472	0.528	0.000
E50 Vitamin A deficiency	0.472	0.528	0.000
E60 Dietary zinc deficiency	0.472	0.528	0.000
E59 Dietary selenium deficiency	0.472	0.528	0.000
E52 Niacin deficiency [pellagra]	0.472	0.528	0.000
E63 Other nutritional deficiencies	0.461	0.538	0.000
E10.3 With ophthalmic complications	0.453	0.547	0.000
E56 Other vitamin deficiencies	0.447	0.552	0.000
E51 Thiamine deficiency	0.447	0.553	0.000
E13.8 With unspecified complications	0.440	0.560	0.000
E13.7 With multiple complications	0.440	0.560	0.000
E13.6 With other specified complications	0.440	0.560	0.000
E13.5 With peripheral circulatory complications	0.440	0.560	0.000
E13.4 With neurological complications	0.440	0.560	0.000
E13.2 With renal complications	0.440	0.560	0.000
E13.1 With ketoacidosis	0.440	0.560	0.000
E13.0 With coma	0.440	0.560	0.000
E61.9 Deficiency of nutrient element, unspecified	0.436	0.564	0.000
E61.8 Deficiency of other specified nutrient elements	0.436	0.564	0.000
E61.7 Deficiency of multiple nutrient elements	0.436	0.564	0.000
E61.6 Vanadium deficiency	0.436	0.564	0.000
E61.5 Molybdenum deficiency	0.436	0.564	0.000
E61.4 Chromium deficiency	0.436	0.564	0.000
E61.3 Manganese deficiency	0.436	0.564	0.000
E61.0 Copper deficiency	0.436	0.564	0.000
E61.2 Magnesium deficiency	0.424	0.576	0.000
E13.3 With ophthalmic complications	0.419	0.580	0.000
E13.9 Without complications	0.386	0.613	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.353	0.646	0.000
E45 Retarded development following protein-energy malnutrition	0.353	0.646	0.000
E43 Unspecified severe protein-energy malnutrition	0.353	0.646	0.000
E42 Marasmic kwashiorkor	0.353	0.646	0.000
E41 Nutritional marasmus	0.353	0.646	0.000
E40 Kwashiorkor	0.353	0.646	0.000
E55 Vitamin D deficiency	0.353	0.647	0.000
E15 Nondiabetic hypoglycaemic coma	0.352	0.648	0.000
E50.9 Vitamin A deficiency, unspecified	0.338	0.661	0.000
E50.8 Other manifestations of vitamin A deficiency	0.338	0.661	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.338	0.661	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.338	0.661	0.000
E50.5 Vitamin A deficiency with night blindness	0.338	0.661	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.338	0.661	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.338	0.661	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.338	0.661	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.338	0.661	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.338	0.661	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.338	0.661	0.000
E64.8 Sequelae of other nutritional deficiencies	0.338	0.661	0.000
E64.3 Sequelae of rickets	0.338	0.661	0.000
E64.2 Sequelae of vitamin C deficiency	0.338	0.661	0.000
E64.1 Sequelae of vitamin A deficiency	0.338	0.661	0.000
E64.0 Sequelae of protein-energy malnutrition	0.338	0.661	0.000
E63.8 Other specified nutritional deficiencies	0.331	0.669	0.000
E63.1 Imbalance of constituents of food intake	0.331	0.669	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.331	0.669	0.000
E56.9 Vitamin deficiency, unspecified	0.321	0.679	0.000
E56.8 Deficiency of other vitamins	0.321	0.679	0.000
E56.0 Deficiency of vitamin E	0.321	0.679	0.000
E51.9 Thiamine deficiency, unspecified	0.321	0.679	0.000
E51.8 Other manifestations of thiamine deficiency	0.321	0.679	0.000
E51.1 Beriberi	0.321	0.679	0.000
E63.9 Nutritional deficiency, unspecified	0.320	0.679	0.000
E10.1 With ketoacidosis	0.307	0.693	0.000
E56.1 Deficiency of vitamin K	0.296	0.703	0.000
E51.2 Wernicke's encephalopathy	0.296	0.704	0.000
E44.1 Mild protein-energy malnutrition	0.253	0.746	0.000
E44.0 Moderate protein-energy malnutrition	0.253	0.746	0.000
E55.0 Rickets, active	0.253	0.747	0.000
E53 Deficiency of other B group vitamins	0.239	0.760	0.001
E46 Unspecified protein-energy malnutrition	0.186	0.813	0.001
E16 Other disorders of pancreatic internal secretion	0.182	0.818	0.000
E53.1 Pyridoxine deficiency	0.172	0.828	0.001
E53.0 Riboflavin deficiency	0.172	0.828	0.001
I10 Essential (primary) hypertension	0.160	0.840	0.000
E53.9 Vitamin B deficiency, unspecified	0.142	0.858	0.001
E55.9 Vitamin D deficiency, unspecified	0.134	0.866	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.130	0.869	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.130	0.869	0.000
E16.4 Abnormal secretion of gastrin	0.130	0.869	0.000
E16.3 Increased secretion of glucagon	0.130	0.869	0.000
E16.1 Other hypoglycaemia	0.124	0.876	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.113	0.887	0.000
I10-I15 Hypertensive diseases	0.091	0.909	0.000
I84.6 Residual haemorrhoidal skin tags	0.087	0.913	0.000
G56.0 Carpal tunnel syndrome	0.076	0.924	0.000
I15 Secondary hypertension	0.075	0.925	0.000
E00-E07 Disorders of thyroid gland	0.072	0.928	0.000
I13 Hypertensive heart and renal disease	0.070	0.930	0.000
I12 Hypertensive renal disease	0.069	0.931	0.000
I15.1 Hypertension secondary to other renal disorders	0.061	0.939	0.000
I15.8 Other secondary hypertension	0.059	0.941	0.000
I12.9 Hypertensive renal disease without renal failure	0.059	0.941	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.059	0.941	0.000
I15.0 Renovascular hypertension	0.057	0.943	0.000
I11 Hypertensive heart disease	0.055	0.945	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.055	0.945	0.000
I15.9 Seconday hypertension, unspecified	0.052	0.948	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.052	0.948	0.000
E00 Congenital iodine-deficiency syndrome	0.052	0.948	0.000
I15.2 Hypertension secondary to endocrine disorders	0.051	0.949	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.051	0.949	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.050	0.950	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.050	0.950	0.000
E07 Other disorders of thyroid	0.048	0.952	0.000
I12.0 Hypertensive renal disease with renal failure	0.041	0.959	0.000
E70-E90 Metabolic disorders	0.040	0.960	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.040	0.960	0.000
Z86.4 Personal history of psychoactive substance abuse	0.038	0.962	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.037	0.963	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.037	0.963	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.037	0.963	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.037	0.963	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.037	0.963	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.037	0.963	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.037	0.963	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.037	0.963	0.000
E07.9 Disorder of thyroid, unspecified	0.036	0.964	0.000
E16.2 Hypoglycaemia, unspecified	0.035	0.965	0.000
E07.1 Dyshormogenetic goitre	0.034	0.965	0.000
E07.0 Hypersecretion of calcitonin	0.034	0.965	0.000
E85 Amyloidosis	0.034	0.965	0.000
E84 Cystic fibrosis	0.032	0.968	0.000
E53.8 Deficiency of other specified B group vitamins	0.031	0.968	0.001
E70 Disorders of aromatic amino-acid metabolism	0.030	0.970	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.030	0.970	0.000
E79 Disorders of purine and pyrimidine metabolism	0.030	0.970	0.000
E76 Disorders of glycosaminoglycan metabolism	0.029	0.971	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.029	0.971	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.029	0.971	0.000
E77 Disorders of glycoprotein metabolism	0.029	0.971	0.000
E07.8 Other specified disorders of thyroid	0.029	0.971	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.029	0.971	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.028	0.971	0.000
E73 Lactose intolerance	0.028	0.972	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.027	0.973	0.000
E74 Other disorders of carbohydrate metabolism	0.027	0.973	0.000
E85.4 Organ-limited amyloidosis	0.027	0.973	0.000
E85.3 Secondary systemic amyloidosis	0.027	0.973	0.000
E85.9 Amyloidosis, unspecified	0.026	0.973	0.000
E72 Other disorders of amino-acid metabolism	0.026	0.973	0.000
E85.8 Other amyloidosis	0.026	0.974	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.025	0.974	0.000
E84.9 Cystic fibrosis, unspecified	0.025	0.975	0.000
G56 Mononeuropathies of upper limb	0.025	0.975	0.000
E20-E35 Disorders of other endocrine glands	0.022	0.975	0.003
E80 Disorders of porphyrin and bilirubin metabolism	0.025	0.975	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.025	0.975	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.025	0.975	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.025	0.975	0.000
E06 Thyroiditis	0.024	0.975	0.000
E78.8 Other disorders of lipoprotein metabolism	0.024	0.976	0.000
E84.8 Cystic fibrosis with other manifestations	0.023	0.976	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.023	0.976	0.000
E78.3 Hyperchylomicronaemia	0.023	0.977	0.000
E78.5 Hyperlipidaemia, unspecified	0.023	0.977	0.000
E70.3 Albinism	0.023	0.977	0.000
E88 Other metabolic disorders	0.023	0.977	0.000
E05.8 Other thyrotoxicosis	0.023	0.977	0.000
E78.6 Lipoprotein deficiency	0.023	0.977	0.000
E78.1 Pure hyperglyceridaemia	0.023	0.977	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.022	0.977	0.000
E03 Other hypothyroidism	0.022	0.978	0.000
E78.0 Pure hypercholesterolaemia	0.022	0.978	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.022	0.978	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.022	0.978	0.000
E70.2 Disorders of tyrosine metabolism	0.022	0.978	0.000
E70.1 Other hyperphenylalaninaemias	0.022	0.978	0.000
E70.0 Classical phenylketonuria	0.022	0.978	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.021	0.978	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.021	0.978	0.000
E79.1 Lesch-Nyhan syndrome	0.021	0.978	0.000
E75.2 Other sphingolipidosis	0.021	0.978	0.000
E74.0 Glycogen storage disease	0.021	0.979	0.000
O48 Prolonged pregnancy	0.000	0.979	0.021
E71.3 Disorders of fatty-acid metabolism	0.021	0.979	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.021	0.979	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.021	0.979	0.000
E71.0 Maple-syrup-urine disease	0.021	0.979	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.021	0.979	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.021	0.979	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.021	0.979	0.000
E76.2 Other mucopolysaccharidoses	0.021	0.979	0.000
E76.1 Mucopolysaccharidosis, type II	0.021	0.979	0.000
E76.0 Mucopolysaccharidosis, type I	0.021	0.979	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.021	0.979	0.000
E77.1 Defects in glycoprotein degradation	0.021	0.979	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.021	0.979	0.000
E77.8 Other disorders of glycoprotein metabolism	0.021	0.979	0.000
E75.6 Lipid storage disorder, unspecified	0.021	0.979	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.021	0.979	0.000
E75.3 Sphingolipidosis, unspecified	0.021	0.979	0.000
E75.1 Other gangliosidosis	0.021	0.979	0.000
E75.0 GM2 gangliosidosis	0.021	0.979	0.000
E78.4 Other hyperlipidaemia	0.021	0.979	0.000
E73.8 Other lactose intolerance	0.020	0.979	0.000
E73.1 Secondary lactase deficiency	0.020	0.979	0.000
E73.0 Congenital lactase deficiency	0.020	0.979	0.000
I84.4 External haemorrhoids with other complications	0.020	0.980	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.020	0.980	0.000
I85.9 Oesophageal varices without bleeding	0.020	0.980	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.020	0.980	0.000
E73.9 Lactose intolerance, unspecified	0.020	0.980	0.000
I84 Haemorrhoids	0.020	0.980	0.000
J22 Unspecified acute lower respiratory infection	0.020	0.980	0.000
I85 Oesophageal varices	0.020	0.980	0.000
E05.5 Thyroid crisis or storm	0.020	0.980	0.000
E05.4 Thyrotoxicosis factitia	0.020	0.980	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.020	0.980	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.020	0.980	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.020	0.980	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.020	0.980	0.000
E74.2 Disorders of galactose metabolism	0.020	0.980	0.000
E74.1 Disorders of fructose metabolism	0.020	0.980	0.000
E75.5 Other lipid storage disorders	0.020	0.980	0.000
E80.6 Other disorders of bilirubin metabolism	0.020	0.980	0.000
G56.8 Other mononeuropathies of upper limb	0.020	0.980	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.020	0.980	0.000
E78.2 Mixed hyperlipidaemia	0.019	0.981	0.000
E80.1 Porphyria cutanea tarda	0.019	0.981	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.019	0.981	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.019	0.981	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.019	0.981	0.000
E72.5 Disorders of glycine metabolism	0.019	0.981	0.000
E72.4 Disorders of ornithine metabolism	0.019	0.981	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.019	0.981	0.000
E72.2 Disorders of urea cycle metabolism	0.019	0.981	0.000
E32 Diseases of thymus	0.017	0.981	0.002
G56.3 Lesion of radial nerve	0.019	0.981	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.019	0.981	0.000
E34 Other endocrine disorders	0.017	0.981	0.002
E88.3 Tumour lysis syndrome	0.019	0.981	0.000
I89.0 Lymphoedema, not elsewhere classified	0.018	0.982	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.016	0.982	0.003
E30 Disorders of puberty, not elsewhere classified	0.016	0.982	0.003
E80.5 Crigler-Najjar syndrome	0.018	0.982	0.000
E80.3 Defects of catalase and peroxydase	0.018	0.982	0.000
E80.0 Hereditary erythropoietic porphyria	0.018	0.982	0.000
E72.0 Disorders of amino-acid transport	0.018	0.982	0.000
G56.1 Other lesions of median nerve	0.018	0.982	0.000
I82 Other venous embolism and thrombosis	0.018	0.982	0.000
E26 Hyperaldosteronism	0.016	0.982	0.002
E20 Hypoparathyroidism	0.016	0.982	0.002
I80 Phlebitis and thrombophlebitis	0.018	0.982	0.000
E06.4 Drug-induced thyroiditis	0.018	0.982	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.018	0.982	0.000
E06.0 Acute thyroiditis	0.018	0.982	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.018	0.982	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.018	0.982	0.000
E31 Polyglandular dysfunction	0.015	0.982	0.003
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.018	0.982	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.017	0.982	0.000
E80.2 Other porphyria	0.017	0.983	0.000
G59.0 Diabetic mononeuropathy	0.017	0.983	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.017	0.983	0.000
G56.4 Causalgia	0.017	0.983	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.017	0.983	0.000
E06.1 Subacute thyroiditis	0.016	0.983	0.000
E25 Adrenogenital disorders	0.014	0.983	0.003
E06.5 Other chronic thyroiditis	0.016	0.984	0.000
E03.5 Myxoedema coma	0.016	0.984	0.000
E03.4 Atrophy of thyroid (acquired)	0.016	0.984	0.000
E03.3 Postinfectious hypothyroidism	0.016	0.984	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.016	0.984	0.000
I82.8 Embolism and thrombosis of other specified veins	0.016	0.984	0.000
E88.8 Other specified metabolic disorders	0.016	0.984	0.000
E29 Testicular dysfunction	0.014	0.984	0.002
I84.0 Internal thrombosed haemorrhoids	0.016	0.984	0.000
G40-G47 Episodic and paroxysmal disorders	0.016	0.984	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.015	0.984	0.000
E88.2 Lipomatosis, not elsewhere classified	0.015	0.984	0.000
E28 Ovarian dysfunction	0.013	0.984	0.003
I81 Portal vein thrombosis	0.015	0.985	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.015	0.985	0.000
E34.9 Endocrine disorder, unspecified	0.014	0.985	0.001
E88.9 Metabolic disorder, unspecified	0.015	0.985	0.000
I85.0 Oesophageal varices with bleeding	0.015	0.985	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.015	0.985	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.015	0.985	0.000
I89.1 Lymphangitis	0.014	0.985	0.000
G43.1 Migraine with aura [classical migraine]	0.015	0.985	0.000
E03.1 Congenital hypothyroidism without goitre	0.014	0.986	0.000
I82.3 Embolism and thrombosis of renal vein	0.014	0.986	0.000
E32.9 Disease of thymus, unspecified	0.013	0.986	0.002
E32.8 Other diseases of thymus	0.013	0.986	0.002
G47.3 Sleep apnoea	0.014	0.986	0.000
I82.0 Budd-Chiari syndrome	0.014	0.986	0.000
E26.9 Hyperaldosteronism, unspecified	0.013	0.986	0.002
G45.9 Transient cerebral ischaemic attack, unspecified	0.014	0.986	0.000
G43 Migraine	0.014	0.986	0.000
I88 Nonspecific lymphadenitis	0.014	0.986	0.000
E24 Cushing's syndrome	0.011	0.986	0.003
G59 Mononeuropathy in diseases classified elsewhere	0.014	0.986	0.000
E32.1 Abscess of thymus	0.012	0.986	0.002
E32.0 Persistent hyperplasia of thymus	0.012	0.986	0.002
G47 Sleep disorders	0.014	0.986	0.000
E20.1 Pseudohypoparathyroidism	0.012	0.986	0.002
G44 Other headache syndromes	0.014	0.986	0.000
E34.0 Carcinoid syndrome	0.012	0.986	0.001
E34.5 Androgen resistance syndrome	0.012	0.986	0.002
E34.4 Constitutional tall stature	0.012	0.986	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.012	0.986	0.002
E34.1 Other hypersecretion of intestinal hormones	0.012	0.986	0.002
I82.9 Embolism and thrombosis of unspecified vein	0.014	0.986	0.000
E30.9 Disorder of puberty, unspecified	0.011	0.986	0.002
E30.8 Other disorders of puberty	0.011	0.986	0.002
E30.1 Precocious puberty	0.011	0.986	0.002
E30.0 Delayed puberty	0.011	0.986	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.011	0.986	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.011	0.986	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.011	0.986	0.002
E03.8 Other specified hypothyroidism	0.013	0.987	0.000
K76.8 Other specified diseases of liver	0.000	0.987	0.013
I82.1 Thrombophlebitis migrans	0.013	0.987	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.013	0.987	0.000
E34.3 Short stature, not elsewhere classified	0.012	0.987	0.002
E26.8 Other hyperaldosteronism	0.011	0.987	0.002
E26.1 Secondary hyperaldosteronism	0.011	0.987	0.002
E20.0 Idiopathic hypoparathyroidism	0.011	0.987	0.002
E34.8 Other specified endocrine disorders	0.012	0.987	0.002
E22 Hyperfunction of pituitary gland	0.011	0.987	0.003
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.013	0.987	0.000
G44.2 Tension-type headache	0.013	0.987	0.000
E31.9 Polyglandular dysfunction, unspecified	0.011	0.987	0.002
E31.8 Other polyglandular dysfunction	0.011	0.987	0.002
E31.1 Polyglandular hyperfunction	0.011	0.987	0.002
G46 Vascular syndromes of brain in cerebrovascular diseases	0.013	0.987	0.000
E20.8 Other hypoparathyroidism	0.011	0.987	0.002
I86 Varicose veins of other sites	0.013	0.987	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.012	0.987	0.000
E06.3 Autoimmune thyroiditis	0.012	0.987	0.000
E20.9 Hypoparathyroidism, unspecified	0.011	0.988	0.002
I84.1 Internal haemorrhoids with other complications	0.012	0.988	0.000
E31.0 Autoimmune polyglandular failure	0.010	0.988	0.002
E25.9 Adrenogenital disorder, unspecified	0.010	0.988	0.002
E25.8 Other adrenogenital disorders	0.010	0.988	0.002
E23 Hypofunction and other disorders of pituitary gland	0.007	0.988	0.005
G41 Status epilepticus	0.012	0.988	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.012	0.988	0.000
G43.8 Other migraine	0.012	0.988	0.000
E06.9 Thyroiditis, unspecified	0.011	0.988	0.001
E29.8 Other testicular dysfunction	0.010	0.988	0.002
E29.0 Testicular hyperfunction	0.010	0.988	0.002
I82.2 Embolism and thrombosis of vena cava	0.012	0.988	0.000
E29.9 Testicular dysfunction, unspecified	0.010	0.988	0.002
G50-G59 Nerve, nerve root and plexus disorders	0.011	0.989	0.000
E28.9 Ovarian dysfunction, unspecified	0.009	0.989	0.002
E28.8 Other ovarian dysfunction	0.009	0.989	0.002
E28.1 Androgen excess	0.009	0.989	0.002
E28.0 Oestrogen excess	0.009	0.989	0.002
I87 Other disorders of veins	0.011	0.989	0.000
E26.0 Primary hyperaldosteronism	0.009	0.989	0.002
G44.4 Drug-induced headache, not elsewhere classified	0.011	0.989	0.000
E87.5 Hyperkalaemia	0.011	0.989	0.000
I86.8 Varicose veins of other specified sites	0.011	0.989	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.011	0.989	0.000
G45.0 Vertebro-basilar artery syndrome	0.011	0.989	0.000
G43.0 Migraine without aura [common migraine]	0.011	0.989	0.000
S83.2 Tear of meniscus, current	0.011	0.989	0.000
I88.8 Other nonspecific lymphadenitis	0.010	0.989	0.000
G45.3 Amaurosis fugax	0.011	0.989	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.011	0.989	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.011	0.989	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.008	0.989	0.003
E28.2 Polycystic ovarian syndrome	0.009	0.989	0.001
G43.3 Complicated migraine	0.010	0.990	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.990	0.003
G44.0 Cluster headache syndrome	0.010	0.990	0.000
G46.4 Cerebellar stroke syndrome	0.010	0.990	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.010	0.990	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.010	0.990	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.008	0.990	0.002
E24.3 Ectopic ACTH syndrome	0.008	0.990	0.002
E24.1 Nelson's syndrome	0.008	0.990	0.002
Chapter IX Diseases of the circulatory system	0.010	0.990	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.010	0.990	0.000
E24.8 Other Cushing's syndrome	0.008	0.990	0.002
G47.2 Disorders of the sleep-wake schedule	0.010	0.990	0.000
G44.1 Vascular headache, not elsewhere classified	0.010	0.990	0.000
I84.3 External thrombosed haemorrhoids	0.010	0.990	0.000
G44.3 Chronic posttraumatic headache	0.010	0.990	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.010	0.990	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.010	0.990	0.000
E24.0 Pituitary-dependent Cushing's disease	0.008	0.990	0.002
G46.3 Brain stem stroke syndrome	0.010	0.990	0.000
H54.7 Unspecified visual loss	0.010	0.990	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.010	0.990	0.000
N80.9 Endometriosis, unspecified	0.000	0.990	0.010
G45.1 Carotid artery syndrome (hemispheric)	0.010	0.990	0.000
G47.4 Narcolepsy and cataplexy	0.010	0.990	0.000
G43.2 Status migrainosus	0.010	0.990	0.000
G46.7 Other lacunar syndromes	0.010	0.990	0.000
E80.4 Gilbert's syndrome	0.010	0.990	0.000
E22.8 Other hyperfunction of pituitary gland	0.008	0.990	0.002
G40 Epilepsy	0.010	0.990	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.008	0.990	0.002
E29.1 Testicular hypofunction	0.008	0.990	0.002
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.009	0.990	0.000
G46.6 Pure sensory lacunar syndrome	0.009	0.990	0.000
G46.5 Pure motor lacunar syndrome	0.009	0.990	0.000
G46.1 Anterior cerebral artery syndrome	0.009	0.990	0.000
G46.0 Middle cerebral artery syndrome	0.009	0.990	0.000
G45.4 Transient global amnesia	0.009	0.991	0.000
G46.2 Posterior cerebral artery syndrome	0.009	0.991	0.000
I86.0 Sublingual varices	0.009	0.991	0.000
G41.9 Status epilepticus, unspecified	0.009	0.991	0.000
G47.8 Other sleep disorders	0.009	0.991	0.000
I86.4 Gastric varices	0.009	0.991	0.000
I86.2 Pelvic varices	0.009	0.991	0.000
E28.3 Primary ovarian failure	0.007	0.991	0.002
G41.8 Other status epilepticus	0.009	0.991	0.000
G41.0 Grand mal status epilepticus	0.009	0.991	0.000
E24.9 Cushing's syndrome, unspecified	0.007	0.991	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.991	0.004
E23.1 Drug-induced hypopituitarism	0.005	0.991	0.004
G41.1 Petit mal status epilepticus	0.009	0.991	0.000
G41.2 Complex partial status epilepticus	0.009	0.991	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.991	0.003
I87.9 Disorder of vein, unspecified	0.009	0.991	0.000
E23.6 Other disorders of pituitary gland	0.006	0.991	0.003
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.009	0.991	0.000
I86.3 Vulval varices	0.009	0.991	0.000
Chapter VI Diseases of the nervous system	0.009	0.991	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.007	0.991	0.001
E87.1 Hypo-osmolality and hyponatraemia	0.009	0.991	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.991	0.003
G47.9 Sleep disorder, unspecified	0.009	0.991	0.000
I87.1 Compression of vein	0.009	0.991	0.000
E22.0 Acromegaly and pituitary gigantism	0.007	0.991	0.002
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.008	0.992	0.000
E27 Other disorders of adrenal gland	0.005	0.992	0.003
E04 Other non-toxic goitre	0.008	0.992	0.000
G54 Nerve root and plexus disorders	0.008	0.992	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations