TreeWAS – Variant ID: rs12479254

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.208	0.792	0.000
E10 Insulin-dependent diabetes mellitus	0.175	0.825	0.000
E10.1 With ketoacidosis	0.151	0.849	0.000
E10.2 With renal complications	0.149	0.851	0.000
E10.5 With peripheral circulatory complications	0.148	0.852	0.000
E10.6 With other specified complications	0.133	0.867	0.000
E10.0 With coma	0.130	0.869	0.000
E10.8 With unspecified complications	0.127	0.873	0.000
E10.7 With multiple complications	0.118	0.882	0.000
E10.3 With ophthalmic complications	0.108	0.892	0.000
E10-E14 Diabetes mellitus	0.095	0.905	0.000
E11.4 With neurological complications	0.094	0.906	0.000
E11 Non-insulin-dependent diabetes mellitus	0.091	0.909	0.000
E10.4 With neurological complications	0.080	0.920	0.000
E11.2 With renal complications	0.075	0.925	0.000
E11.3 With ophthalmic complications	0.073	0.927	0.000
E11.6 With other specified complications	0.072	0.928	0.000
E12 Malnutrition-related diabetes mellitus	0.068	0.932	0.000
E11.8 With unspecified complications	0.067	0.933	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.935	0.065
E11.7 With multiple complications	0.065	0.935	0.000
E11.1 With ketoacidosis	0.057	0.943	0.000
E13 Other specified diabetes mellitus	0.054	0.946	0.000
E11.5 With peripheral circulatory complications	0.051	0.949	0.000
E12.9 Without complications	0.049	0.951	0.000
E12.8 With unspecified complications	0.049	0.951	0.000
E12.7 With multiple complications	0.049	0.951	0.000
E12.6 With other specified complications	0.049	0.951	0.000
E12.5 With peripheral circulatory complications	0.049	0.951	0.000
E12.4 With neurological complications	0.049	0.951	0.000
E12.3 With ophthalmic complications	0.049	0.951	0.000
E12.2 With renal complications	0.049	0.951	0.000
E12.1 With ketoacidosis	0.049	0.951	0.000
E12.0 With coma	0.049	0.951	0.000
E11.0 With coma	0.043	0.957	0.000
E13.3 With ophthalmic complications	0.041	0.959	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.000	0.960	0.040
E13.8 With unspecified complications	0.039	0.961	0.000
E13.7 With multiple complications	0.039	0.961	0.000
E13.6 With other specified complications	0.039	0.961	0.000
E13.5 With peripheral circulatory complications	0.039	0.961	0.000
E13.4 With neurological complications	0.039	0.961	0.000
E13.2 With renal complications	0.039	0.961	0.000
E13.1 With ketoacidosis	0.039	0.961	0.000
E13.0 With coma	0.039	0.961	0.000
Y54.3 Benzothiadiazine derivatives	0.038	0.962	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.037	0.963	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.035	0.965	0.000
E14 Unspecified diabetes mellitus	0.033	0.966	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.032	0.968	0.000
Y40 Systemic antibiotics	0.032	0.968	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.031	0.969	0.000
Y57 Other and unspecified drugs and medicaments	0.031	0.969	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.031	0.969	0.000
Y40.0 Penicillins	0.031	0.969	0.000
Y54.7 Agents affecting calcification	0.030	0.970	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.030	0.970	0.000
N93.0 Postcoital and contact bleeding	0.000	0.970	0.030
Y57.5 X-ray contrast media	0.029	0.971	0.000
Y54.4 Loop [high-ceiling] diuretics	0.028	0.972	0.000
Y54.5 Other diuretics	0.028	0.972	0.000
E14.2 Withrenal complications	0.027	0.972	0.000
E14.4 With neurological complications	0.027	0.973	0.000
Y57.9 Drug or medicament, unspecified	0.027	0.973	0.000
Y54.0 Mineralocorticoids	0.027	0.973	0.000
Y44 Agents primarily affecting blood constituents	0.027	0.973	0.000
Y54.9 Mineral salts, not elsewhere classified	0.026	0.973	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.026	0.973	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.026	0.973	0.000
E14.6 With other specified complications	0.026	0.974	0.000
Y40.6 Rifamycins	0.026	0.974	0.000
Y57.8 Other drugs and medicaments	0.026	0.974	0.000
Y40.8 Other systemic antibiotics	0.026	0.974	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.025	0.975	0.000
Y40.3 Macrolides	0.025	0.975	0.000
E14.0 With coma	0.025	0.975	0.000
E14.1 With ketoacidosis	0.025	0.975	0.000
Y40.4 Tetracyclines	0.024	0.976	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.024	0.976	0.000
Y41.5 Antiviral drugs	0.024	0.976	0.000
E14.7 With multiple complications	0.024	0.976	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.024	0.976	0.000
Y40.5 Aminoglycosides	0.024	0.976	0.000
Y41.0 Sulphonamides	0.024	0.976	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.024	0.976	0.000
Y54.8 Agents affecting uric acid metabolism	0.024	0.976	0.000
Y41.1 Antimycobacterial drugs	0.023	0.976	0.000
Y59 Other and unspecified vaccines and biological substances	0.023	0.976	0.000
Y44.2 Anticoagulants	0.024	0.976	0.000
Y48 Anaesthetics and therapeutic gases	0.023	0.977	0.000
Y40.2 Chloramphenicol group	0.023	0.977	0.000
Y43 Primarily systemic agents	0.023	0.977	0.000
Y40.7 Antifungal antibiotics, systemically used	0.023	0.977	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.023	0.977	0.000
Y58 Bacterial vaccines	0.023	0.977	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.023	0.977	0.000
Y41.4 Anthelminthics	0.023	0.977	0.000
Y41.3 Other antiprotozoal drugs	0.023	0.977	0.000
Y57.7 Vitamins, not elsewhere classified	0.023	0.977	0.000
Y57.4 Pharmaceutical excipients	0.023	0.977	0.000
Y57.3 Alcohol deterrents	0.023	0.977	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.023	0.977	0.000
Y57.1 Lipotropic drugs	0.023	0.977	0.000
Y57.0 Appetite depressants [anorectics]	0.023	0.977	0.000
Y43.4 Immunosuppressive agents	0.022	0.978	0.000
Y47.1 Benzodiazepines	0.020	0.979	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.020	0.979	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.020	0.980	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.020	0.980	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.020	0.980	0.000
E13.9 Without complications	0.020	0.980	0.000
Y52 Agents primarily affecting the cardiovascular system	0.020	0.980	0.000
E14.3 With ophthalmic complications	0.020	0.980	0.000
Y44.6 Natural blood and blood products	0.019	0.980	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.019	0.980	0.000
Y43.2 Antineoplastic natural products	0.019	0.980	0.000
E14.5 With peripheral circulatory complications	0.019	0.981	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.019	0.981	0.000
Y44.7 Plasma substitutes	0.019	0.981	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.019	0.981	0.000
Y48.4 Anaesthetic, unspecified	0.019	0.981	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.019	0.981	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.019	0.981	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.019	0.981	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.019	0.981	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.018	0.982	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.018	0.982	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.018	0.982	0.000
Y47.4 Bromine compounds	0.018	0.982	0.000
Y47.3 Paraldehyde	0.018	0.982	0.000
Y47.2 Chloral derivatives	0.018	0.982	0.000
Y47.0 Barbiturates, not elsewhere classified	0.018	0.982	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.018	0.982	0.000
Y44.5 Thrombolytic drugs	0.018	0.982	0.000
Y57.6 Other diagnostic agents	0.018	0.982	0.000
Y59.0 Viral vaccines	0.018	0.982	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.018	0.982	0.000
Y50.9 Central nervous system stimulant, unspecified	0.018	0.982	0.000
Y50.8 Other central nervous system stimulants	0.018	0.982	0.000
Y50.1 Opioid receptor antagonists	0.018	0.982	0.000
Y50.0 Analeptics	0.018	0.982	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.018	0.982	0.000
Y59.9 Vaccine or biological substance, unspecified	0.017	0.983	0.000
Y59.8 Other specified vaccines and biological substances	0.017	0.983	0.000
Y59.2 Protozoal vaccines	0.017	0.983	0.000
Y59.1 Rickettsial vaccines	0.017	0.983	0.000
Y48.5 Therapeutic gases	0.017	0.983	0.000
Y48.1 Parenteral anaesthetics	0.017	0.983	0.000
Y48.0 Inhaled anaesthetics	0.017	0.983	0.000
Y43.9 Primarily systemic agent, unspecified	0.017	0.983	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.017	0.983	0.000
Y43.6 Enzymes, not elsewhere classified	0.017	0.983	0.000
Y43.5 Acidifying and alkalising agents	0.017	0.983	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.017	0.983	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.017	0.983	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.017	0.983	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.017	0.983	0.000
Y51.0 Anticholinesterase agents	0.017	0.983	0.000
Y59.3 Immunoglobulin	0.017	0.983	0.000
Y58.9 Other and unspecified bacterial vaccines	0.017	0.983	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.017	0.983	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.017	0.983	0.000
Y58.5 Diphtheria vaccine	0.017	0.983	0.000
Y58.4 Tetanus vaccine	0.017	0.983	0.000
Y58.3 Plague vaccine	0.017	0.983	0.000
Y58.2 Cholera vaccine	0.017	0.983	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.017	0.983	0.000
E14.8 With unspecified complications	0.016	0.983	0.000
Y40.9 Systemic antibiotic, unspecified	0.016	0.984	0.000
Y58.0 BCG vaccine	0.016	0.984	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.016	0.984	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.016	0.984	0.000
Y48.2 Other and unspecified general anaesthetics	0.016	0.984	0.000
Y46.5 Valproic acid	0.015	0.984	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.015	0.984	0.000
Y48.3 Local anaesthetics	0.015	0.984	0.000
Y46.7 Anti-Parkinsonism drugs	0.015	0.984	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.015	0.985	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.015	0.985	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.015	0.985	0.000
Y55.5 Anticommon cold drugs	0.015	0.985	0.000
Y55.3 Antitussives	0.015	0.985	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.015	0.985	0.000
Y55.0 Oxytocic drugs	0.015	0.985	0.000
Y46.8 Antispasticity drugs	0.015	0.985	0.000
Y46.3 Deoxybarbiturates	0.015	0.985	0.000
Y46.1 Oxazolidinediones	0.015	0.985	0.000
Y46.0 Succinimides	0.015	0.985	0.000
Y52.7 Peripheral vasodilators	0.015	0.985	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.015	0.985	0.000
Y56.9 Topical agent, unspecified	0.015	0.985	0.000
Y56.8 Other topical agents	0.015	0.985	0.000
Y56.7 Dental drugs, topically applied	0.015	0.985	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.015	0.985	0.000
Y56.5 Ophthalmological drugs and preparations	0.015	0.985	0.000
Y56.2 Local astringents and local detergents	0.015	0.985	0.000
Y56.1 Antipruritics	0.015	0.985	0.000
Y46.2 Hydantoin derivatives	0.015	0.985	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.015	0.985	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.014	0.985	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.014	0.986	0.000
Y53.7 Emetics	0.014	0.986	0.000
Y53.6 Antidiarrhoeal drugs	0.014	0.986	0.000
Y53.5 Digestants	0.014	0.986	0.000
Y53.3 Saline and osmotic laxatives	0.014	0.986	0.000
Y53.0 Histamine H2-receptor antagonists	0.014	0.986	0.000
Y43.1 Antineoplastic antimetabolites	0.014	0.986	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.014	0.986	0.000
Y52.1 Calcium-channel blockers	0.014	0.986	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
Y46.6 Other and unspecified antiepileptics	0.014	0.986	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.014	0.986	0.000
N92.4 Excessive bleeding in the premenopausal period	0.000	0.986	0.014
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.013	0.987	0.000
Y53.2 Stimulant laxatives	0.013	0.987	0.000
N92 Excessive, frequent and irregular menstruation	0.000	0.987	0.013
Y56.3 Emollients, demulcents and protectants	0.013	0.987	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.013	0.987	0.000
Y55.4 Expectorants	0.013	0.987	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.013	0.987	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.013	0.987	0.000
Y43.0 Antiallergic and antiemetic drugs	0.012	0.988	0.000
Z34.0 Supervision of normal first pregnancy	0.012	0.988	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.988	0.000
Y46.4 Iminostilbenes	0.011	0.989	0.000
Y53.4 Other laxatives	0.011	0.989	0.000
E11.9 Without complications	0.011	0.989	0.000
Y45.1 Salicylates	0.011	0.989	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.989	0.011
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.011	0.989	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.989	0.000
N92.6 Irregular menstruation, unspecified	0.000	0.990	0.010
Y49.9 Psychotropic drug, unspecified	0.010	0.990	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
Y49.7 Psychostimulants with abuse potential	0.010	0.990	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.010	0.990	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.010	0.990	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.010	0.990	0.000
Y45.4 Antirheumatics	0.010	0.990	0.000
E05.8 Other thyrotoxicosis	0.010	0.990	0.000
N92.2 Excessive menstruation at puberty	0.000	0.990	0.010
Y45.2 Propionic acid derivatives	0.010	0.990	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.009	0.990	0.000
Y45.5 4-Aminophenol derivatives	0.009	0.990	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.009	0.991	0.000
E05.5 Thyroid crisis or storm	0.009	0.991	0.000
E05.4 Thyrotoxicosis factitia	0.009	0.991	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.009	0.991	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.009	0.991	0.000
Y43.3 Other antineoplastic drugs	0.009	0.991	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.009	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.992	0.000
N92.5 Other specified irregular menstruation	0.000	0.992	0.008
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.008	0.992	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.008	0.992	0.000
Y49.2 Other and unspecified antidepressants	0.007	0.992	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.007	0.992	0.000
O75.0 Maternal distress during labour and delivery	0.007	0.993	0.000
E00-E07 Disorders of thyroid gland	0.007	0.993	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.993	0.007
Y49.5 Other antipsychotics and neuroleptics	0.007	0.993	0.000
E06 Thyroiditis	0.007	0.993	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.007	0.993	0.000
R40.2 Coma, unspecified	0.000	0.993	0.007
O75 Other complications of labour and delivery, not elsewhere classified	0.007	0.993	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.993	0.007
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.007	0.993	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.994	0.006
E06.9 Thyroiditis, unspecified	0.006	0.994	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
E06.3 Autoimmune thyroiditis	0.006	0.994	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.006	0.994	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.006	0.994	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.994	0.006
I97.1 Other functional disturbances following cardiac surgery	0.000	0.994	0.006
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.994	0.000
E00 Congenital iodine-deficiency syndrome	0.005	0.994	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.005	0.995	0.000
O75.8 Other specified complications of labour and delivery	0.005	0.995	0.000
M10.99 Gout, unspecified (Site unspecified)	0.005	0.995	0.000
A40.8 Other streptococcal septicaemia	0.005	0.995	0.000
O75.3 Other infection during labour	0.005	0.995	0.000
E06.4 Drug-induced thyroiditis	0.005	0.995	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.005	0.995	0.000
E06.0 Acute thyroiditis	0.005	0.995	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.005	0.995	0.000
I97.0 Postcardiotomy syndrome	0.000	0.995	0.005
O75.9 Complication of labour and delivery, unspecified	0.005	0.995	0.000
O75.4 Other complications of obstetric surgery and procedures	0.005	0.995	0.000
O75.1 Shock during or following labour and delivery	0.005	0.995	0.000
E06.5 Other chronic thyroiditis	0.005	0.995	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.005	0.995	0.000
Y42.4 Oral contraceptives	0.005	0.995	0.000
Y42.1 Thyroid hormones and substitutes	0.005	0.995	0.000
E06.1 Subacute thyroiditis	0.005	0.995	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.995	0.005
Y42.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
Z98.1 Arthrodesis status	0.000	0.995	0.005
E40-E46 Malnutrition	0.005	0.995	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.005	0.995	0.000
D13.1 Stomach	0.005	0.995	0.000
E16.1 Other hypoglycaemia	0.005	0.995	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.995	0.004
I99 Other and unspecified disorders of circulatory system	0.000	0.995	0.005
B37.9 Candidiasis, unspecified	0.004	0.996	0.000
A40.0 Septicaemia due to streptococcus, group A	0.004	0.996	0.000
B37.8 Candidiasis of other sites	0.004	0.996	0.000
E16 Other disorders of pancreatic internal secretion	0.004	0.996	0.000
A40 Streptococcal septicaemia	0.004	0.996	0.000
K07.6 Temporomandibular joint disorders	0.004	0.996	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.004	0.996	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.004	0.996	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.004	0.996	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.004	0.996	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.004	0.996	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.004	0.996	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.004	0.996	0.000
E15 Nondiabetic hypoglycaemic coma	0.004	0.996	0.000
N89.5 Stricture and atresia of vagina	0.000	0.996	0.004
S51.0 Open wound of elbow	0.000	0.996	0.004
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
E65-E68 Obesity and other hyperalimentation	0.004	0.996	0.000
Y42.7 Androgens and anabolic congeners	0.004	0.996	0.000
Y42.2 Antithyroid drugs	0.003	0.996	0.000
B37.3 Candidiasis of vulva and vagina	0.004	0.996	0.000
E07 Other disorders of thyroid	0.004	0.996	0.000
A40.9 Streptococcal septicaemia, unspecified	0.004	0.996	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.996	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.004	0.996	0.000
E45 Retarded development following protein-energy malnutrition	0.004	0.996	0.000
E43 Unspecified severe protein-energy malnutrition	0.004	0.996	0.000
E42 Marasmic kwashiorkor	0.004	0.996	0.000
E41 Nutritional marasmus	0.004	0.996	0.000
E40 Kwashiorkor	0.004	0.996	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.996	0.004
A40.1 Septicaemia due to streptococcus, group B	0.003	0.996	0.000
B37 Candidiasis	0.004	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.997	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.997	0.000
E16.4 Abnormal secretion of gastrin	0.003	0.997	0.000
E16.3 Increased secretion of glucagon	0.003	0.997	0.000
A40.2 Septicaemia due to streptococcus, group D	0.003	0.997	0.000
E03 Other hypothyroidism	0.003	0.997	0.000
E65 Localised adiposity	0.003	0.997	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.003	0.997	0.000
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
N20.0 Calculus of kidney	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
E67 Other hyperalimentation	0.003	0.997	0.000
E68 Sequelae of hyperalimentation	0.003	0.997	0.000
R76.8 Other specified abnormal immunological findings in serum	0.003	0.997	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.003	0.997	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.997	0.003
M16.9 Coxarthrosis, unspecified	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
E07.1 Dyshormogenetic goitre	0.003	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.003	0.997	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.997	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.997	0.003
M43.17 Spondylolisthesis (Lumbosacral region)	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
B37.6 Candidal endocarditis	0.003	0.997	0.000
B37.5 Candidal meningitis	0.003	0.997	0.000
E03.1 Congenital hypothyroidism without goitre	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.003	0.997	0.000
K51.4 Pseudopolyposis of colon	0.000	0.997	0.003
E03.5 Myxoedema coma	0.003	0.997	0.000
E03.4 Atrophy of thyroid (acquired)	0.003	0.997	0.000
E03.3 Postinfectious hypothyroidism	0.003	0.997	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.003	0.997	0.000
W02.9 Unspecified place	0.003	0.997	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.003	0.997	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.003	0.997	0.000
W07.0 Home	0.003	0.997	0.000
B37.7 Candidal septicaemia	0.003	0.997	0.000
E03.8 Other specified hypothyroidism	0.003	0.997	0.000
D13.3 Other and unspecified parts of small intestine	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.997	0.001
E04 Other non-toxic goitre	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.003	0.997	0.000
D13.2 Duodenum	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
Z34 Supervision of normal pregnancy	0.003	0.997	0.000
E50-E64 Other nutritional deficiencies	0.002	0.997	0.000
B37.4 Candidiasis of other urogenital sites	0.002	0.997	0.000
H43.3 Other vitreous opacities	0.003	0.997	0.000
E67.8 Other specified hyperalimentation	0.002	0.997	0.000
E67.3 Hypervitaminosis D	0.002	0.997	0.000
E67.2 Megavitamin-B6 syndrome	0.002	0.997	0.000
E67.1 Hypercarotenaemia	0.002	0.997	0.000
E67.0 Hypervitaminosis A	0.002	0.997	0.000
D13.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
D13.6 Pancreas	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.998	0.002
M96.4 Postsurgical lordosis	0.000	0.998	0.002
M96.3 Postlaminectomy kyphosis	0.000	0.998	0.002
M96.2 Postradiation kyphosis	0.000	0.998	0.002
D13.7 Endocrine pancreas	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.002	0.998	0.000
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.000	0.998	0.002
C71.2 Temporal lobe	0.002	0.998	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.002
M96.5 Postradiation scoliosis	0.000	0.998	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
E54 Ascorbic acid deficiency	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.002
H52.1 Myopia	0.002	0.998	0.000
B37.2 Candidiasis of skin and nail	0.002	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.002
O86.4 Pyrexia of unknown origin following delivery	0.002	0.998	0.000
B49 Unspecified mycosis	0.002	0.998	0.000
E51 Thiamine deficiency	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
R52.9 Pain, unspecified	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
N89.6 Tight hymenal ring	0.000	0.998	0.002
O86.8 Other specified puerperal infections	0.002	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.002	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.002	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.002	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.000	0.998	0.002
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
B37.1 Pulmonary candidiasis	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.001	0.998	0.001
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.002	0.998	0.000
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
B35-B49 Mycoses	0.002	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.002	0.998	0.000
Z93.1 Gastrostomy status	0.000	0.998	0.002
D13.0 Oesophagus	0.002	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.002	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.002	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.002	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.000	0.998	0.002
E58 Dietary calcium deficiency	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations