TreeWAS – Variant ID: rs12500426

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.801	0.199	0.000
C61 Malignant neoplasm of prostate	0.000	0.268	0.732
I74.5 Embolism and thrombosis of iliac artery	0.478	0.522	0.000
I74 Arterial embolism and thrombosis	0.463	0.537	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.458	0.542	0.000
I71 Aortic aneurysm and dissection	0.456	0.544	0.000
I77 Other disorders of arteries and arterioles	0.443	0.557	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.441	0.559	0.000
I77.1 Stricture of artery	0.431	0.569	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.403	0.597	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.402	0.598	0.000
I77.2 Rupture of artery	0.394	0.606	0.000
I70 Atherosclerosis	0.374	0.626	0.000
I77.8 Other specified disorders of arteries and arterioles	0.371	0.629	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.362	0.638	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.356	0.644	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.355	0.644	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.350	0.650	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.345	0.655	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.341	0.658	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.332	0.668	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.327	0.673	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.327	0.673	0.000
I77.3 Arterial fibromuscular dysplasia	0.325	0.675	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.325	0.675	0.000
I77.5 Necrosis of artery	0.318	0.682	0.000
I77.4 Coeliac artery compression syndrome	0.318	0.682	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.312	0.688	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.310	0.690	0.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.699	0.301
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.291	0.709	0.000
I71.0 Dissection of aorta [any part]	0.291	0.709	0.000
I77.6 Arteritis, unspecified	0.289	0.711	0.000
I77.0 Arteriovenous fistula, acquired	0.288	0.712	0.000
I74.8 Embolism and thrombosis of other arteries	0.287	0.713	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.284	0.716	0.000
I73 Other peripheral vascular diseases	0.278	0.722	0.000
I72 Other aneurysm	0.274	0.726	0.000
I70.9 Generalised and unspecified atherosclerosis	0.269	0.731	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.266	0.734	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.261	0.739	0.000
I79.1 Aortitis in diseases classified elsewhere	0.259	0.740	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.259	0.740	0.000
I70.1 Atherosclerosis of renal artery	0.257	0.743	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.246	0.754	0.000
I70.8 Atherosclerosis of other arteries	0.244	0.756	0.000
C60 Malignant neoplasm of penis	0.000	0.757	0.243
R32 Unspecified urinary incontinence	0.000	0.758	0.242
I72.0 Aneurysm of carotid artery	0.217	0.783	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.215	0.784	0.000
I72.4 Aneurysm of artery of lower extremity	0.214	0.786	0.000
I73.8 Other specified peripheral vascular diseases	0.211	0.789	0.000
I72.2 Aneurysm of renal artery	0.210	0.790	0.000
I70.0 Atherosclerosis of aorta	0.208	0.792	0.000
I73.0 Raynaud's syndrome	0.203	0.797	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.798	0.202
I72.6 Aneurysm and dissection of vertebral artery	0.197	0.803	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.197	0.803	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.194	0.806	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.193	0.807	0.000
C62 Malignant neoplasm of testis	0.000	0.808	0.192
C60.9 Penis, unspecified	0.000	0.808	0.192
C60.1 Glans penis	0.000	0.812	0.188
I70.11 Atherosclerosis of renal artery (with gangrene)	0.184	0.815	0.000
I72.1 Aneurysm of artery of upper extremity	0.182	0.818	0.000
I72.3 Aneurysm of iliac artery	0.181	0.819	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.175	0.825	0.000
C60.8 Overlapping lesion of penis	0.000	0.826	0.174
C60.2 Body of penis	0.000	0.826	0.174
I70.10 Atherosclerosis of renal artery (without gangrene)	0.174	0.826	0.000
C60.0 Prepuce	0.000	0.828	0.172
I78 Diseases of capillaries	0.169	0.831	0.000
I72.9 Aneurysm of unspecified site	0.166	0.834	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.151	0.849	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.149	0.850	0.000
C63.9 Male genital organ, unspecified	0.000	0.855	0.145
C63.8 Overlapping lesion of male genital organs	0.000	0.855	0.145
C63.7 Other specified male genital organs	0.000	0.855	0.145
C63.1 Spermatic cord	0.000	0.855	0.145
C63.0 Epididymis	0.000	0.855	0.145
C62.0 Undescended testis	0.000	0.862	0.138
I78.9 Disease of capillaries, unspecified	0.138	0.862	0.000
C62.1 Descended testis	0.000	0.866	0.134
I72.8 Aneurysm of other specified arteries	0.134	0.866	0.000
C63.2 Scrotum	0.000	0.868	0.131
I77.9 Disorder of arteries and arterioles, unspecified	0.130	0.870	0.000
C62.9 Testis, unspecified	0.000	0.880	0.120
I78.8 Other diseases of capillaries	0.106	0.893	0.000
H40 Glaucoma	0.096	0.904	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.089	0.910	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.085	0.915	0.000
I44.1 Atrioventricular block, second degree	0.085	0.915	0.000
I73.9 Peripheral vascular disease, unspecified	0.083	0.917	0.000
H40.5 Glaucoma secondary to other eye disorders	0.073	0.927	0.000
H40.6 Glaucoma secondary to drugs	0.072	0.928	0.000
H40.4 Glaucoma secondary to eye inflammation	0.070	0.930	0.000
H40.2 Primary angle-closure glaucoma	0.063	0.937	0.000
H40.3 Glaucoma secondary to eye trauma	0.056	0.944	0.000
H40.8 Other glaucoma	0.056	0.944	0.000
H40.1 Primary open-angle glaucoma	0.042	0.958	0.000
H40-H42 Glaucoma	0.040	0.960	0.000
M79.60 Pain in limb (Multiple sites)	0.035	0.965	0.000
I34.0 Mitral (valve) insufficiency	0.033	0.967	0.000
I50.1 Left ventricular failure	0.032	0.968	0.000
I44 Atrioventricular and left bundle-branch block	0.031	0.969	0.000
I50 Heart failure	0.031	0.969	0.000
I30-I52 Other forms of heart disease	0.030	0.970	0.000
I33 Acute and subacute endocarditis	0.030	0.970	0.000
I34 Nonrheumatic mitral valve disorders	0.030	0.970	0.000
I33.0 Acute and subacute infective endocarditis	0.029	0.971	0.000
H42 Glaucoma in diseases classified elsewhere	0.029	0.971	0.000
H40.0 Glaucoma suspect	0.029	0.971	0.000
I45 Other conduction disorders	0.029	0.971	0.000
I78.1 Naevus, nonneoplastic	0.028	0.972	0.000
I30 Acute pericarditis	0.028	0.972	0.000
I45.6 Preexcitation syndrome	0.028	0.972	0.000
M34.9 Systemic sclerosis, unspecified	0.028	0.972	0.000
Chapter IX Diseases of the circulatory system	0.027	0.973	0.000
I30.9 Acute pericarditis, unspecified	0.027	0.973	0.000
I45.8 Other specified conduction disorders	0.027	0.973	0.000
I45.9 Conduction disorder, unspecified	0.026	0.974	0.000
I99 Other and unspecified disorders of circulatory system	0.026	0.974	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.025	0.975	0.000
M34 Systemic sclerosis	0.025	0.975	0.000
I33.9 Acute endocarditis, unspecified	0.024	0.976	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.024	0.976	0.000
I50.0 Congestive heart failure	0.024	0.976	0.000
M34.1 CR(E)ST syndrome	0.023	0.977	0.000
I40 Acute myocarditis	0.023	0.977	0.000
I44.5 Left posterior fascicular block	0.023	0.977	0.000
I45.4 Nonspecific intraventricular block	0.023	0.977	0.000
I37 Pulmonary valve disorders	0.022	0.978	0.000
I42 Cardiomyopathy	0.022	0.978	0.000
M34.8 Other forms of systemic sclerosis	0.022	0.978	0.000
I52 Other heart disorders in diseases classified elsewhere	0.022	0.978	0.000
I48 Atrial fibrillation and flutter	0.022	0.978	0.000
I41 Myocarditis in diseases classified elsewhere	0.022	0.978	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.022	0.978	0.000
I32 Pericarditis in diseases classified elsewhere	0.022	0.978	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.022	0.978	0.000
I45.2 Bifascicular block	0.022	0.978	0.000
I44.4 Left anterior fascicular block	0.021	0.978	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.021	0.979	0.000
I42.0 Dilated cardiomyopathy	0.021	0.979	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.021	0.979	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.021	0.979	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.021	0.979	0.000
I44.6 Other and unspecified fascicular block	0.021	0.979	0.000
I50.9 Heart failure, unspecified	0.021	0.979	0.000
M34.0 Progressive systemic sclerosis	0.020	0.980	0.000
I30.8 Other forms of acute pericarditis	0.020	0.980	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.020	0.980	0.000
I30.1 Infective pericarditis	0.020	0.980	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.019	0.981	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.019	0.981	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.019	0.981	0.000
I45.0 Right fascicular block	0.019	0.981	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.018	0.981	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.018	0.981	0.000
I00-I02 Acute rheumatic fever	0.018	0.981	0.000
I42.2 Other hypertrophic cardiomyopathy	0.018	0.982	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.018	0.982	0.000
I40.9 Acute myocarditis, unspecified	0.018	0.982	0.000
I45.3 Trifascicular block	0.018	0.982	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.017	0.983	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.017	0.983	0.000
I37.1 Pulmonary valve insufficiency	0.017	0.983	0.000
I42.5 Other restrictive cardiomyopathy	0.017	0.983	0.000
I40.8 Other acute myocarditis	0.017	0.983	0.000
I40.1 Isolated myocarditis	0.017	0.983	0.000
I36 Nonrheumatic tricuspid valve disorders	0.016	0.984	0.000
I37.0 Pulmonary valve stenosis	0.016	0.984	0.000
I37.9 Pulmonary valve disorder, unspecified	0.016	0.984	0.000
I37.8 Other pulmonary valve disorders	0.016	0.984	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.016	0.984	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.016	0.984	0.000
I40.0 Infective myocarditis	0.016	0.984	0.000
I44.3 Other and unspecified atrioventricular block	0.016	0.984	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.016	0.984	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.016	0.984	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.016	0.984	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.016	0.984	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.016	0.984	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.016	0.984	0.000
I44.2 Atrioventricular block, complete	0.016	0.984	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.016	0.984	0.000
I48.4 Atypical atrial flutter	0.016	0.984	0.000
I48.3 Typical atrial flutter	0.016	0.984	0.000
I48.2 Chronic atrial fibrillation	0.016	0.984	0.000
I48.1 Persistent atrial fibrillation	0.016	0.984	0.000
I48.0 Paroxysmal atrial fibrillation	0.016	0.984	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.016	0.984	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.016	0.984	0.000
K37 Unspecified appendicitis	0.000	0.984	0.016
T43.2 Other and unspecified antidepressants	0.015	0.985	0.000
I42.9 Cardiomyopathy, unspecified	0.015	0.985	0.000
I42.8 Other cardiomyopathies	0.015	0.985	0.000
I05-I09 Chronic rheumatic heart diseases	0.015	0.985	0.000
I44.0 Atrioventricular block, first degree	0.015	0.985	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.014	0.986	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.014	0.986	0.000
I98.0 Cardiovascular syphilis	0.014	0.986	0.000
H54.9 Unspecified visual impairment (binocular)	0.014	0.986	0.000
I08 Multiple valve diseases	0.014	0.986	0.000
S01.2 Open wound of nose	0.014	0.986	0.000
I02 Rheumatic chorea	0.013	0.986	0.000
I01 Rheumatic fever with heart involvement	0.013	0.986	0.000
I42.4 Endocardial fibroelastosis	0.013	0.987	0.000
I46 Cardiac arrest	0.013	0.987	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.013	0.987	0.000
K38 Other diseases of appendix	0.000	0.987	0.013
I34.1 Mitral (valve) prolapse	0.013	0.987	0.000
I08.0 Disorders of both mitral and aortic valves	0.013	0.987	0.000
H54.7 Unspecified visual loss	0.013	0.987	0.000
K35-K38 Diseases of appendix	0.000	0.987	0.013
K38.1 Appendicular concretions	0.000	0.988	0.012
H54 Blindness and low vision	0.012	0.988	0.000
I45.5 Other specified heart block	0.012	0.988	0.000
I00 Rheumatic fever without mention of heart involvement	0.012	0.988	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.012	0.988	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.012	0.988	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.012	0.988	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.012	0.988	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.012	0.988	0.000
K36 Other appendicitis	0.000	0.988	0.012
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.012	0.988	0.000
H54.0 Blindness, both eyes	0.012	0.988	0.000
I08.8 Other multiple valve diseases	0.011	0.988	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.011	0.989	0.000
K38.8 Other specified diseases of appendix	0.000	0.989	0.011
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.011	0.989	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.011	0.989	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.011	0.989	0.000
I09 Other rheumatic heart diseases	0.010	0.989	0.000
H54.2 Low vision, both eyes	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
K38.0 Hyperplasia of appendix	0.000	0.990	0.010
I42.6 Alcoholic cardiomyopathy	0.010	0.990	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.010	0.990	0.000
I01.8 Other acute rheumatic heart disease	0.010	0.990	0.000
I01.2 Acute rheumatic myocarditis	0.010	0.990	0.000
I01.1 Acute rheumatic endocarditis	0.010	0.990	0.000
I01.0 Acute rheumatic pericarditis	0.010	0.990	0.000
I02.9 Rheumatic chorea without heart involvement	0.010	0.990	0.000
I02.0 Rheumatic chorea with heart involvement	0.010	0.990	0.000
K38.9 Disease of appendix, unspecified	0.000	0.990	0.010
I46.1 Sudden cardiac death, so described	0.010	0.990	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.010	0.990	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.009	0.990	0.000
H54.5 Low vision, one eye	0.010	0.990	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.009	0.990	0.000
K38.3 Fistula of appendix	0.000	0.990	0.009
I08.9 Multiple valve disease, unspecified	0.009	0.991	0.000
I97.0 Postcardiotomy syndrome	0.009	0.991	0.000
I06 Rheumatic aortic valve diseases	0.009	0.991	0.000
H54.3 Unqualified visual loss, both eyes	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
I44.7 Left bundle-branch block, unspecified	0.009	0.991	0.000
H54.6 Unqualified visual loss, one eye	0.009	0.991	0.000
I46.0 Cardiac arrest with successful resuscitation	0.009	0.991	0.000
I28 Other diseases of pulmonary vessels	0.008	0.992	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.008	0.992	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
K38.2 Diverticulum of appendix	0.000	0.992	0.008
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.008	0.992	0.000
I09.8 Other specified rheumatic heart diseases	0.008	0.992	0.000
I09.2 Chronic rheumatic pericarditis	0.008	0.992	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.008	0.992	0.000
I09.0 Rheumatic myocarditis	0.008	0.992	0.000
I97.1 Other functional disturbances following cardiac surgery	0.008	0.992	0.000
I09.9 Rheumatic heart disease, unspecified	0.007	0.992	0.000
I10-I15 Hypertensive diseases	0.007	0.993	0.000
I07 Rheumatic tricuspid valve diseases	0.007	0.993	0.001
H54.1 Blindness, one eye, low vision, other eye	0.007	0.993	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.993	0.007
N48.6 Balanitis xerotica obliterans	0.000	0.993	0.007
I38 Endocarditis, valve unspecified	0.007	0.993	0.000
I47 Paroxysmal tachycardia	0.007	0.993	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.007	0.993	0.000
I06.8 Other rheumatic aortic valve diseases	0.007	0.993	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.007	0.993	0.000
N48.1 Balanoposthitis	0.000	0.993	0.007
Z98.0 Intestinal bypass and anastomosis status	0.000	0.993	0.007
I28.8 Other specified diseases of pulmonary vessels	0.007	0.993	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.993	0.007
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.006	0.993	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.994	0.006
I06.1 Rheumatic aortic insufficiency	0.006	0.994	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.006	0.994	0.000
I28.1 Aneurysm of pulmonary artery	0.006	0.994	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.006	0.994	0.000
N48 Other disorders of penis	0.000	0.994	0.006
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.994	0.006
I11 Hypertensive heart disease	0.006	0.994	0.000
I47.2 Ventricular tachycardia	0.006	0.994	0.000
I05 Rheumatic mitral valve diseases	0.006	0.994	0.000
I06.0 Rheumatic aortic stenosis	0.005	0.994	0.000
I15 Secondary hypertension	0.006	0.994	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.006	0.994	0.000
I07.9 Tricuspid valve disease, unspecified	0.005	0.994	0.001
I07.8 Other tricuspid valve diseases	0.005	0.994	0.001
I07.2 Tricuspid stenosis with insufficiency	0.005	0.994	0.001
I07.0 Tricuspid stenosis	0.005	0.994	0.001
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.006	0.994	0.000
N48.4 Impotence of organic origin	0.000	0.995	0.005
I27 Other pulmonary heart diseases	0.005	0.995	0.000
K46 Unspecified abdominal hernia	0.005	0.995	0.000
J92.0 Pleural plaque with presence of asbestos	0.005	0.995	0.000
I13 Hypertensive heart and renal disease	0.005	0.995	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.005	0.995	0.000
N48.5 Ulcer of penis	0.000	0.995	0.005
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.005	0.995	0.000
I15.2 Hypertension secondary to endocrine disorders	0.005	0.995	0.000
I27.9 Pulmonary heart disease, unspecified	0.005	0.995	0.000
I86.1 Scrotal varices	0.000	0.995	0.005
F10.1 Harmful use	0.005	0.995	0.000
I05.1 Rheumatic mitral insufficiency	0.005	0.995	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.005	0.995	0.000
I15.0 Renovascular hypertension	0.005	0.995	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.005	0.995	0.000
I15.1 Hypertension secondary to other renal disorders	0.004	0.995	0.000
N48.3 Priapism	0.000	0.996	0.004
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.996	0.004
N48.9 Disorder of penis, unspecified	0.000	0.996	0.004
I31 Other diseases of pericardium	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
O63.9 Long labour, unspecified	0.000	0.996	0.004
I05.8 Other mitral valve diseases	0.004	0.996	0.000
I47.0 Reentry ventricular arrhythmia	0.004	0.996	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.004	0.996	0.000
F10.3 Withdrawal state	0.004	0.996	0.000
I05.2 Mitral stenosis with insufficiency	0.004	0.996	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
F17.1 Harmful use	0.004	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.996	0.004
I15.9 Seconday hypertension, unspecified	0.004	0.996	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.004	0.996	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.004	0.996	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.004	0.996	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.004	0.996	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.004	0.996	0.000
H54.4 Blindness, one eye	0.004	0.996	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.996	0.004
I15.8 Other secondary hypertension	0.004	0.996	0.000
Z89.5 Acquired absence of leg at or below knee	0.004	0.996	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.996	0.004
F10.7 Residual and late-onset psychotic disorder	0.004	0.996	0.000
F10.6 Amnesic syndrome	0.004	0.996	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
I46.9 Cardiac arrest, unspecified	0.004	0.996	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.004	0.996	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.996	0.004
J84.9 Interstitial pulmonary disease, unspecified	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.003	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.996	0.004
D51 Vitamin B12 deficiency anaemia	0.000	0.996	0.004
F17 Mental and behavioural disorders due to use of tobacco	0.003	0.997	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
I31.8 Other specified diseases of pericardium	0.003	0.997	0.000
I31.2 Haemopericardium, not elsewhere classified	0.003	0.997	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
F10.8 Other mental and behavioural disorders	0.003	0.997	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.003	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.997	0.003
F50.9 Eating disorder, unspecified	0.003	0.997	0.000
I31.0 Chronic adhesive pericarditis	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.003	0.997	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.997	0.003
J84 Other interstitial pulmonary diseases	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.997	0.003
F14.2 Dependence syndrome	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
I26 Pulmonary embolism	0.003	0.997	0.000
O73.0 Retained placenta, without haemorrhage	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
F10.4 Withdrawal state with delirium	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
F17.0 Acute intoxication	0.003	0.997	0.000
F14.1 Harmful use	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
F12.1 Harmful use	0.003	0.997	0.000
I31.1 Chronic constrictive pericarditis	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.003	0.997	0.000
F17.3 Withdrawal state	0.003	0.997	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.003	0.997	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
F10.0 Acute intoxication	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
F12.2 Dependence syndrome	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.000	0.997	0.003
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.997	0.003
F10.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F10.5 Psychotic disorder	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.997	0.003
N48.0 Leukoplakia of penis	0.000	0.997	0.003
F11 Mental and behavioural disorders due to use of opioids	0.003	0.997	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.003	0.997	0.000
F50 Eating disorders	0.003	0.997	0.000
F60 Specific personality disorders	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.997	0.003
F17.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F17.8 Other mental and behavioural disorders	0.003	0.997	0.000
F17.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F17.6 Amnesic syndrome	0.003	0.997	0.000
F17.5 Psychotic disorder	0.003	0.997	0.000
F17.4 Withdrawal state with delirium	0.003	0.997	0.000
F14.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F14.8 Other mental and behavioural disorders	0.003	0.997	0.000
F14.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F14.6 Amnesic syndrome	0.003	0.997	0.000
F14.5 Psychotic disorder	0.003	0.997	0.000
F14.4 Withdrawal state with delirium	0.003	0.997	0.000
F14.3 Withdrawal state	0.003	0.997	0.000
F14.0 Acute intoxication	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.997	0.003
F60.5 Anankastic personality disorder	0.003	0.997	0.000
M33.1 Other dermatomyositis	0.003	0.997	0.000
F12.9 Unspecified mental and behavioural disorder	0.002	0.997	0.000
F12.8 Other mental and behavioural disorders	0.002	0.997	0.000
F12.7 Residual and late-onset psychotic disorder	0.002	0.997	0.000
F12.6 Amnesic syndrome	0.002	0.997	0.000
F12.5 Psychotic disorder	0.002	0.997	0.000
F12.4 Withdrawal state with delirium	0.002	0.997	0.000
F12.3 Withdrawal state	0.002	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.997	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.997	0.002
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.997	0.002
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.997	0.002
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.997	0.002
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.997	0.002
F12.0 Acute intoxication	0.002	0.997	0.000
M33.2 Polymyositis	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
J92 Pleural plaque	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.002	0.997	0.000
I12 Hypertensive renal disease	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
T38.7 Androgens and anabolic congeners	0.002	0.997	0.000
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
T38.4 Oral contraceptives	0.002	0.997	0.000
T38.2 Antithyroid drugs	0.002	0.997	0.000
J84.8 Other specified interstitial pulmonary diseases	0.002	0.997	0.000
F81 Specific developmental disorders of scholastic skills	0.003	0.997	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.997	0.003
C71 Malignant neoplasm of brain	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations