TreeWAS – Variant ID: rs12508709

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J43.9 Emphysema, unspecified	0.000	0.747	0.253
J43 Emphysema	0.000	0.758	0.242
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.769	0.231
J44 Other chronic obstructive pulmonary disease	0.000	0.769	0.231
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.775	0.225
J43.2 Centrilobular emphysema	0.000	0.788	0.212
J40-J47 Chronic lower respiratory diseases	0.000	0.788	0.212
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.790	0.210
J43.8 Other emphysema	0.000	0.803	0.197
J42 Unspecified chronic bronchitis	0.000	0.819	0.181
J43.1 Panlobular emphysema	0.000	0.827	0.173
J43.0 MacLeod's syndrome	0.000	0.827	0.173
J41 Simple and mucopurulent chronic bronchitis	0.000	0.857	0.143
J46 Status asthmaticus	0.000	0.873	0.127
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.897	0.103
J41.1 Mucopurulent chronic bronchitis	0.000	0.897	0.103
J41.0 Simple chronic bronchitis	0.000	0.906	0.093
J40 Bronchitis, not specified as acute or chronic	0.000	0.912	0.088
J45 Asthma	0.000	0.931	0.069
J45.0 Predominantly allergic asthma	0.000	0.951	0.049
J45.1 Nonallergic asthma	0.000	0.953	0.047
J45.8 Mixed asthma	0.000	0.957	0.043
Y42.5 Other oestrogens and progestogens	0.000	0.969	0.031
K65 Peritonitis	0.000	0.970	0.030
K65.0 Acute peritonitis	0.000	0.971	0.029
K65.8 Other peritonitis	0.000	0.971	0.029
J47 Bronchiectasis	0.000	0.973	0.027
S82.20 Fracture of shaft of tibia (closed)	0.026	0.974	0.000
K65.9 Peritonitis, unspecified	0.000	0.975	0.025
M54.16 Radiculopathy (Lumbar region)	0.000	0.975	0.025
K66 Other disorders of peritoneum	0.000	0.975	0.025
K65-K67 Diseases of peritoneum	0.000	0.975	0.025
K66.8 Other specified disorders of peritoneum	0.000	0.976	0.024
K66.1 Haemoperitoneum	0.000	0.978	0.022
K66.9 Disorder of peritoneum, unspecified	0.000	0.980	0.020
I35.9 Aortic valve disorder, unspecified	0.000	0.981	0.019
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.981	0.018
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.982	0.018
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.982	0.018
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.982	0.018
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.982	0.018
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.982	0.018
I35.1 Aortic (valve) insufficiency	0.000	0.982	0.018
O32.0 Maternal care for unstable lie	0.000	0.983	0.017
O32.4 Maternal care for high head at term	0.000	0.983	0.017
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.983	0.017
I35 Nonrheumatic aortic valve disorders	0.000	0.984	0.016
Y42.7 Androgens and anabolic congeners	0.000	0.984	0.016
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.984	0.016
O32.2 Maternal care for transverse and oblique lie	0.000	0.985	0.015
Y42.2 Antithyroid drugs	0.000	0.986	0.014
S82.2 Fracture of shaft of tibia	0.014	0.986	0.000
O32.6 Maternal care for compound presentation	0.000	0.986	0.014
L93.0 Discoid lupus erythematosus	0.000	0.986	0.014
O32.8 Maternal care for other malpresentation of foetus	0.000	0.987	0.013
Y42.9 Other and unspecified hormone antagonists	0.000	0.987	0.013
Y42.4 Oral contraceptives	0.000	0.987	0.013
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.987	0.013
K67.3 Tuberculous peritonitis	0.000	0.987	0.013
K67.2 Syphilitic peritonitis	0.000	0.987	0.013
K67.1 Gonococcal peritonitis	0.000	0.987	0.013
K67.0 Chlamydial peritonitis	0.000	0.987	0.013
Y42.1 Thyroid hormones and substitutes	0.000	0.987	0.013
R60.0 Localised oedema	0.000	0.988	0.012
O32.3 Maternal care for face, brow and chin presentation	0.000	0.989	0.011
S82.21 Fracture of shaft of tibia (open)	0.011	0.989	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.990	0.010
O32.1 Maternal care for breech presentation	0.000	0.990	0.010
K62.7 Radiation proctitis	0.009	0.991	0.000
K66.0 Peritoneal adhesions	0.000	0.992	0.008
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.992	0.008
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.008	0.992	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.992	0.007
H53.0 Amblyopia ex anopsia	0.008	0.992	0.000
O47 False labour	0.000	0.993	0.007
O47.0 False labour before 37 completed weeks of gestation	0.000	0.993	0.007
S27.0 Traumatic pneumothorax	0.007	0.993	0.000
I35.8 Other aortic valve disorders	0.000	0.993	0.007
S20 Superficial injury of thorax	0.007	0.993	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.007	0.993	0.000
M54.1 Radiculopathy	0.000	0.993	0.007
S27 Injury of other and unspecified intrathoracic organs	0.007	0.993	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.993	0.006
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.994	0.006
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.994	0.006
S20.1 Other and unspecified superficial injuries of breast	0.006	0.994	0.000
L93 Lupus erythematosus	0.000	0.994	0.006
O46.9 Antepartum haemorrhage, unspecified	0.000	0.994	0.006
S27.3 Other injuries of lung	0.006	0.994	0.000
S20.4 Other superficial injuries of back wall of thorax	0.006	0.994	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.994	0.006
M54.19 Radiculopathy (Site unspecified)	0.000	0.994	0.006
S82.60 Fracture of lateral malleolus (closed)	0.006	0.994	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.006	0.994	0.000
S20.2 Contusion of thorax	0.006	0.994	0.000
S20.0 Contusion of breast	0.006	0.994	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.006	0.994	0.000
S20-S29 Injuries to the thorax	0.006	0.994	0.000
S27.1 Traumatic haemothorax	0.006	0.994	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.994	0.006
O40 Polyhydramnios	0.000	0.995	0.005
A40.8 Other streptococcal septicaemia	0.005	0.995	0.000
O42 Premature rupture of membranes	0.000	0.995	0.005
S20.7 Multiple superficial injuries of thorax	0.005	0.995	0.000
M54.14 Radiculopathy (Thoracic region)	0.000	0.995	0.005
Z80.8 Family history of malignant neoplasm of other organs or systems	0.005	0.995	0.000
O43 Placental disorders	0.000	0.995	0.005
S22.50 Flail chest (closed)	0.005	0.995	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.995	0.005
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.995	0.005
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.995	0.005
L93.2 Other local lupus erythematosus	0.000	0.995	0.005
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.995	0.005
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.005	0.995	0.000
S27.9 Injury of unspecified intrathoracic organ	0.005	0.995	0.000
S27.7 Multiple injuries of intrathoracic organs	0.005	0.995	0.000
S27.6 Injury of pleura	0.005	0.995	0.000
S27.5 Injury of thoracic trachea	0.005	0.995	0.000
S27.4 Injury of bronchus	0.005	0.995	0.000
S82.6 Fracture of lateral malleolus	0.005	0.995	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.995	0.005
O31 Complications specific to multiple gestation	0.000	0.995	0.005
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.995	0.005
S20.3 Other superficial injuries of front wall of thorax	0.005	0.995	0.000
S27.2 Traumatic heamopneumothorax	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.995	0.005
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.005	0.995	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.005	0.995	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.995	0.005
S27.8 Injury of other specified intrathoracic organs	0.005	0.995	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.004	0.995	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.995	0.004
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.995	0.005
J93.1 Other spontaneous pneumothorax	0.000	0.995	0.005
O43.0 Placental transfusion syndromes	0.000	0.995	0.004
S82 Fracture of lower leg, including ankle	0.004	0.996	0.000
A40.0 Septicaemia due to streptococcus, group A	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
O43.9 Placental disorder, unspecified	0.000	0.996	0.004
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.996	0.004
O30 Multiple gestation	0.000	0.996	0.004
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.004	0.996	0.000
S26 Injury of heart	0.004	0.996	0.000
S25 Injury of blood vessels of thorax	0.004	0.996	0.000
S24 Injury of nerves and spinal cord at thorax level	0.004	0.996	0.000
O46.8 Other antepartum haemorrhage	0.000	0.996	0.004
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.000	0.996	0.004
S22.5 Flail chest	0.004	0.996	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.996	0.004
S21 Open wound of thorax	0.004	0.996	0.000
O43.2 Morbidly adherent placenta	0.000	0.996	0.004
S23.4 Sprain and strain of ribs and sternum	0.004	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.996	0.004
C50.3 Lower-inner quadrant of breast	0.004	0.996	0.000
O43.1 Malformation of placenta	0.000	0.996	0.004
O45 Premature separation of placenta [abruptio placentae]	0.000	0.996	0.004
A40 Streptococcal septicaemia	0.004	0.996	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.996	0.004
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.004	0.996	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.004	0.996	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.004	0.996	0.000
S82.7 Multiple fractures of lower leg	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.996	0.004
S82.61 Fracture of lateral malleolus (open)	0.004	0.996	0.000
O41.0 Oligohydramnios	0.000	0.996	0.004
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.996	0.004
O31.0 Papyraceous foetus	0.000	0.996	0.004
O43.8 Other placental disorders	0.000	0.996	0.004
O31.8 Other complications specific to multiple gestation	0.000	0.996	0.004
S29 Other and unspecified injuries of thorax	0.004	0.996	0.000
O41.1 Infection of amniotic sac and membranes	0.000	0.996	0.004
M54.12 Radiculopathy (Cervical region)	0.000	0.996	0.004
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.004
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.996	0.004
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.004	0.996	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.996	0.004
O47.9 False labour, unspecified	0.000	0.996	0.004
O33.9 Maternal care for disproportion, unspecified	0.000	0.996	0.004
S21.2 Open wound of back wall of thorax	0.004	0.996	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.004	0.996	0.000
O33.8 Maternal care for disproportion of other origin	0.000	0.996	0.003
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.996	0.003
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.996	0.003
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.996	0.003
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.996	0.003
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.996	0.003
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.996	0.003
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.996	0.003
S23.5 Sprain and strain of other and unspecified parts of thorax	0.003	0.996	0.000
S23.3 Sprain and strain of thoracic spine	0.003	0.996	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.003	0.996	0.000
S23.1 Dislocation of thoracic vertebra	0.003	0.996	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.003	0.996	0.000
O36.2 Maternal care for hydrops foetalis	0.000	0.996	0.004
S82.9 Fracture of lower leg, part unspecified	0.004	0.996	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.003	0.996	0.000
S82.70 Multiple fractures of lower leg (closed)	0.003	0.996	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.996	0.003
O36.4 Maternal care for intra-uterine death	0.000	0.996	0.003
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.996	0.003
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.996	0.004
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
O30.1 Triplet pregnancy	0.000	0.997	0.003
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
J92.9 Pleural plaque without asbestos	0.000	0.997	0.003
A40.2 Septicaemia due to streptococcus, group D	0.003	0.997	0.000
O30.9 Multiple gestation, unspecified	0.000	0.997	0.003
O30.8 Other multiple gestation	0.000	0.997	0.003
O30.2 Quadruplet pregnancy	0.000	0.997	0.003
S25.9 Injury of unspecified blood vessel of thorax	0.003	0.997	0.000
S25.8 Injury of other blood vessels of thorax	0.003	0.997	0.000
S25.7 Injury of multiple blood vessels of thorax	0.003	0.997	0.000
S25.5 Injury of intercostal blood vessels	0.003	0.997	0.000
S25.4 Injury of pulmonary blood vessels	0.003	0.997	0.000
S25.3 Injury of innominate or subclavian vein	0.003	0.997	0.000
S25.2 Injury of superior vena cava	0.003	0.997	0.000
S25.1 Injury of innominate or subclavian artery	0.003	0.997	0.000
S25.0 Injury of thoracic aorta	0.003	0.997	0.000
S26.9 Injury of heart, unspecified	0.003	0.997	0.000
S26.8 Other injuries of heart	0.003	0.997	0.000
S26.0 Injury of heart with haemopericardium	0.003	0.997	0.000
S28.1 Traumatic amputation of part of thorax	0.003	0.997	0.000
S28.0 Crushed chest	0.003	0.997	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.997	0.003
S24.6 Injury of unspecified nerve of thorax	0.003	0.997	0.000
S24.5 Injury of other nerves of thorax	0.003	0.997	0.000
S24.4 Injury of thoracic sympathetic nerves	0.003	0.997	0.000
S24.3 Injury of peripheral nerves of thorax	0.003	0.997	0.000
S24.2 Injury of nerve root of thoracic spine	0.003	0.997	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.003	0.997	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.003	0.997	0.000
S22.51 Flail chest (open)	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.997	0.003
G83.4 Cauda equina syndrome	0.003	0.997	0.000
S21.8 Open wound of other parts of thorax	0.003	0.997	0.000
S21.7 Multiple open wounds of thoracic wall	0.003	0.997	0.000
S21.0 Open wound of breast	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.003
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
O36.1 Maternal care for other isoimmunisation	0.000	0.997	0.003
N42.9 Disorder of prostate, unspecified	0.000	0.997	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.997	0.003
A40.1 Septicaemia due to streptococcus, group B	0.003	0.997	0.000
O45.8 Other premature separation of placenta	0.000	0.997	0.003
O45.0 Premature separation of placenta with coagulation defect	0.000	0.997	0.003
S29.8 Other specified injuries of thorax	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
S82.71 Multiple fractures of lower leg (open)	0.003	0.997	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.003	0.997	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.997	0.003
S82.90 Fracture of lower leg, part unspecified (closed)	0.003	0.997	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.003	0.997	0.000
O44 Placenta praevia	0.000	0.997	0.003
J92.0 Pleural plaque with presence of asbestos	0.000	0.997	0.003
S29.7 Multiple injuries of thorax	0.003	0.997	0.000
C18.3 Hepatic flexure	0.000	0.997	0.003
C77.9 Lymph node, unspecified	0.003	0.997	0.000
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
S59.9 Unspecified injury of forearm	0.000	0.997	0.003
J92 Pleural plaque	0.000	0.997	0.003
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
S21.1 Open wound of front wall of thorax	0.003	0.997	0.000
S29.0 Injury of muscle and tendon at thorax level	0.003	0.997	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.997	0.003
S82.91 Fracture of lower leg, part unspecified (open)	0.003	0.997	0.000
C24.0 Extrahepatic bile duct	0.000	0.997	0.003
I35.0 Aortic (valve) stenosis	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
J38.4 Oedema of larynx	0.003	0.997	0.000
S82.4 Fracture of fibula alone	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
S82.51 Fracture of medial malleolus (open)	0.003	0.997	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.002	0.997	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.002	0.997	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.002	0.997	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.002	0.997	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.002	0.997	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.002	0.997	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.997	0.003
S21.9 Open wound of thorax, part unspecified	0.002	0.997	0.000
O30.0 Twin pregnancy	0.000	0.997	0.003
K29.0 Acute haemorrhagic gastritis	0.003	0.997	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.997	0.002
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.997	0.002
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.997	0.002
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.997	0.002
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.997	0.002
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
S82.0 Fracture of patella	0.002	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.997	0.003
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
R60 Oedema, not elsewhere classified	0.000	0.998	0.002
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.000	0.998	0.002
Y48.4 Anaesthetic, unspecified	0.000	0.998	0.002
O45.9 Premature separation of placenta, unspecified	0.001	0.998	0.002
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.998	0.002
J93 Pneumothorax	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.998	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.998	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.998	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
Y48.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
S22.2 Fracture of sternum	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.998	0.002
S22.11 Multiple fractures of thoracic spine (open)	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
S22.3 Fracture of rib	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.002	0.998	0.000
N81.5 Vaginal enterocele	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
G83.9 Paralytic syndrome, unspecified	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
G83 Other paralytic syndromes	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
D12.8 Rectum	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
H36.0 Diabetic retinopathy	0.002	0.998	0.000
R60.1 Generalised oedema	0.000	0.998	0.002
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.000	0.998	0.002
Y48.1 Parenteral anaesthetics	0.000	0.998	0.002
Y48.0 Inhaled anaesthetics	0.000	0.998	0.002
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
J94.1 Fibrothorax	0.000	0.998	0.002
Q85.1 Tuberous sclerosis	0.002	0.998	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
S59 Other and unspecified injuries of forearm	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.998	0.002
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.998	0.002
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.998	0.002
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.998	0.002
Y47.4 Bromine compounds	0.000	0.998	0.002
Y47.3 Paraldehyde	0.000	0.998	0.002
Y47.2 Chloral derivatives	0.000	0.998	0.002
Y47.0 Barbiturates, not elsewhere classified	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
J94 Other pleural conditions	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
F45.8 Other somatoform disorders	0.000	0.998	0.002
Y48.3 Local anaesthetics	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
J93.9 Pneumothorax, unspecified	0.000	0.998	0.002
S54.0 Injury of ulnar nerve at forearm level	0.000	0.998	0.002
S22.31 Fracture of rib (open)	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.000	0.998	0.002
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.998	0.002
J90-J94 Other diseases of pleura	0.000	0.998	0.002
G83.5 Locked-in syndrome	0.002	0.998	0.000
G83.0 Diplegia of upper limbs	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.998	0.001
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.998	0.002
J94.2 Haemothorax	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
Y46.2 Hydantoin derivatives	0.000	0.998	0.002
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
Y58 Bacterial vaccines	0.000	0.998	0.002
K25.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
G83.3 Monoplegia, unspecified	0.001	0.998	0.000
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.001	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
G96 Other disorders of central nervous system	0.000	0.998	0.002
O44.1 Placenta praevia with haemorrhage	0.001	0.998	0.001
Q79.6 Ehlers-Danlos syndrome	0.000	0.998	0.002
S59.8 Other specified injuries of forearm	0.000	0.998	0.001
S59.7 Multiple injuries of forearm	0.000	0.998	0.001
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.001
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.001
Y54.0 Mineralocorticoids	0.000	0.998	0.001
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.998	0.001
G96.0 Cerebrospinal fluid leak	0.000	0.998	0.002
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.002	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.998	0.002
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
G96.8 Other specified disorders of central nervous system	0.000	0.998	0.001
J94.0 Chylous effusion	0.000	0.998	0.001
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.998	0.001
J94.9 Pleural condition, unspecified	0.000	0.998	0.001
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.998	0.001
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
Y57.8 Other drugs and medicaments	0.000	0.998	0.001
Y41.1 Antimycobacterial drugs	0.000	0.998	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.998	0.001
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.999	0.001
C24.8 Overlapping lesion of biliary tract	0.000	0.999	0.001
O92.1 Cracked nipple associated with childbirth	0.000	0.999	0.001
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.001	0.999	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.001	0.999	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.001	0.999	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.001	0.999	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.001	0.999	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.001	0.999	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.001	0.999	0.000
C24.1 Ampulla of Vater	0.000	0.999	0.001
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.999	0.001
G83.8 Other specified paralytic syndromes	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
Y59 Other and unspecified vaccines and biological substances	0.000	0.999	0.001
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
R22.2 Localised swelling, mass and lump, trunk	0.001	0.999	0.000
Y44.5 Thrombolytic drugs	0.000	0.999	0.001
Y54.7 Agents affecting calcification	0.000	0.999	0.001
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
Y55.5 Anticommon cold drugs	0.000	0.999	0.001
Y55.3 Antitussives	0.000	0.999	0.001
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
Y55.0 Oxytocic drugs	0.000	0.999	0.001
Y58.9 Other and unspecified bacterial vaccines	0.000	0.999	0.001
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.999	0.001
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.999	0.001
Y58.5 Diphtheria vaccine	0.000	0.999	0.001
Y58.4 Tetanus vaccine	0.000	0.999	0.001
Y58.3 Plague vaccine	0.000	0.999	0.001
Y58.2 Cholera vaccine	0.000	0.999	0.001
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.999	0.001
S82.40 Fracture of fibula alone (closed)	0.001	0.999	0.000
J93.8 Other pneumothorax	0.000	0.999	0.001
S90.0 Contusion of ankle	0.001	0.999	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.999	0.001
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.999	0.001
M62 Other disorders of muscle	0.001	0.999	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.999	0.001
G96.9 Disorder of central nervous system, unspecified	0.000	0.999	0.001
O73.0 Retained placenta, without haemorrhage	0.001	0.999	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.999	0.001
Y58.0 BCG vaccine	0.000	0.999	0.001
Q61 Cystic kidney disease	0.001	0.999	0.000
S82.30 Fracture of lower end of tibia (closed)	0.001	0.999	0.000
D68.0 Von Willebrand's disease	0.000	0.999	0.001
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations