TreeWAS – Variant ID: rs12531540

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.058	0.942
E11.4 With neurological complications	0.000	0.074	0.926
E11.3 With ophthalmic complications	0.000	0.081	0.919
C44.3 Skin of other and unspecified parts of face	0.908	0.092	0.000
E11.8 With unspecified complications	0.000	0.156	0.844
C44 Other malignant neoplasms of skin	0.791	0.209	0.000
C44.4 Skin of scalp and neck	0.780	0.220	0.000
C44.0 Skin of lip	0.780	0.220	0.000
C44.1 Skin of eyelid, including canthus	0.646	0.354	0.000
E11.7 With multiple complications	0.000	0.392	0.608
C44.8 Overlapping lesion of skin	0.567	0.433	0.000
E11.5 With peripheral circulatory complications	0.000	0.452	0.548
E11.2 With renal complications	0.000	0.497	0.502
E11.0 With coma	0.000	0.536	0.464
C43-C44 Melanoma and other malignant neoplasms of skin	0.439	0.561	0.000
E11.1 With ketoacidosis	0.000	0.596	0.404
E11.6 With other specified complications	0.000	0.608	0.392
C43 Malignant melanoma of skin	0.368	0.632	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.356	0.644	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.348	0.651	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.295	0.705	0.000
C43.0 Malignant melanoma of lip	0.292	0.708	0.000
C43.8 Overlapping malignant melanoma of skin	0.264	0.736	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.254	0.746	0.000
C43.9 Malignant melanoma of skin, unspecified	0.250	0.750	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.246	0.754	0.000
C44.5 Skin of trunk	0.227	0.773	0.000
C43.4 Malignant melanoma of scalp and neck	0.223	0.777	0.000
J33.9 Nasal polyp, unspecified	0.000	0.790	0.210
J33.0 Polyp of nasal cavity	0.000	0.793	0.207
J33 Nasal polyp	0.000	0.794	0.206
C43.5 Malignant melanoma of trunk	0.198	0.802	0.000
J33.8 Other polyp of sinus	0.000	0.811	0.189
C44.6 Skin of upper limb, including shoulder	0.167	0.833	0.000
J33.1 Polypoid sinus degeneration	0.000	0.870	0.130
C43.3 Malignant melanoma of other and unspecified parts of face	0.128	0.872	0.000
C44.7 Skin of lower limb, including hip	0.087	0.913	0.000
E10-E14 Diabetes mellitus	0.000	0.942	0.058
C44.2 Skin of ear and external auricular canal	0.042	0.958	0.001
E12 Malnutrition-related diabetes mellitus	0.000	0.958	0.042
E13 Other specified diabetes mellitus	0.000	0.963	0.037
M35.0 Sicca syndrome [Sjogren]	0.000	0.968	0.032
E12.9 Without complications	0.000	0.970	0.030
E12.8 With unspecified complications	0.000	0.970	0.030
E12.7 With multiple complications	0.000	0.970	0.030
E12.6 With other specified complications	0.000	0.970	0.030
E12.5 With peripheral circulatory complications	0.000	0.970	0.030
E12.4 With neurological complications	0.000	0.970	0.030
E12.3 With ophthalmic complications	0.000	0.970	0.030
E12.2 With renal complications	0.000	0.970	0.030
E12.1 With ketoacidosis	0.000	0.970	0.030
E12.0 With coma	0.000	0.970	0.030
E13.3 With ophthalmic complications	0.000	0.973	0.027
E13.8 With unspecified complications	0.000	0.973	0.026
E13.7 With multiple complications	0.000	0.973	0.026
E13.6 With other specified complications	0.000	0.973	0.026
E13.5 With peripheral circulatory complications	0.000	0.973	0.026
E13.4 With neurological complications	0.000	0.973	0.026
E13.2 With renal complications	0.000	0.973	0.026
E13.1 With ketoacidosis	0.000	0.973	0.026
E13.0 With coma	0.000	0.973	0.026
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.979	0.021
E13.9 Without complications	0.000	0.979	0.021
M25.86 Other specified joint disorders (Lower leg)	0.000	0.982	0.018
M25.8 Other specified joint disorders	0.000	0.982	0.018
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.983	0.017
M25.83 Other specified joint disorders (Forearm)	0.000	0.986	0.014
M25.88 Other specified joint disorders (Other)	0.000	0.986	0.014
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.013	0.987	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.987	0.013
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.987	0.013
K04 Diseases of pulp and periapical tissues	0.013	0.987	0.000
K04.7 Periapical abscess without sinus	0.013	0.987	0.000
M25.82 Other specified joint disorders (Upper arm)	0.000	0.988	0.012
K04.6 Periapical abscess with sinus	0.012	0.988	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.012	0.988	0.000
E14 Unspecified diabetes mellitus	0.000	0.988	0.012
M25.84 Other specified joint disorders (Hand)	0.000	0.989	0.011
K04.0 Pulpitis	0.011	0.989	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.989	0.011
K04.3 Abnormal hard tissue formation in pulp	0.010	0.990	0.000
K04.2 Pulp degeneration	0.010	0.990	0.000
K04.1 Necrosis of pulp	0.010	0.990	0.000
K04.8 Radicular cyst	0.010	0.990	0.000
E14.8 With unspecified complications	0.000	0.991	0.009
E14.6 With other specified complications	0.000	0.991	0.009
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.991	0.009
E14.7 With multiple complications	0.000	0.991	0.009
E14.0 With coma	0.000	0.991	0.009
E14.1 With ketoacidosis	0.000	0.991	0.008
E14.4 With neurological complications	0.000	0.992	0.008
E14.2 Withrenal complications	0.000	0.992	0.008
E10 Insulin-dependent diabetes mellitus	0.000	0.992	0.008
E10.8 With unspecified complications	0.000	0.992	0.008
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.992	0.008
E14.5 With peripheral circulatory complications	0.000	0.993	0.007
M48.06 Spinal stenosis (Lumbar region)	0.000	0.993	0.007
M35 Other systemic involvement of connective tissue	0.000	0.993	0.007
E10.5 With peripheral circulatory complications	0.000	0.993	0.007
D36.1 Peripheral nerves and autonomic nervous system	0.007	0.993	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.994	0.006
E10.0 With coma	0.000	0.994	0.006
M35.7 Hypermobility syndrome	0.000	0.994	0.006
M48.09 Spinal stenosis (Site unspecified)	0.000	0.994	0.006
E10.7 With multiple complications	0.000	0.994	0.006
M48.0 Spinal stenosis	0.000	0.994	0.006
M35.2 Behcet's disease	0.000	0.994	0.006
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.994	0.006
E10.2 With renal complications	0.000	0.994	0.006
E10.4 With neurological complications	0.000	0.994	0.006
E10.6 With other specified complications	0.000	0.995	0.005
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.995	0.005
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.995	0.005
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.995	0.005
M35.5 Multifocal fibrosclerosis	0.000	0.995	0.005
E05.9 Thyrotoxicosis, unspecified	0.000	0.995	0.005
K04.5 Chronic apical periodontitis	0.005	0.995	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.995	0.005
S32.01 Fracture of lumbar vertebra (open)	0.000	0.995	0.005
M35.1 Other overlap syndromes	0.000	0.995	0.005
T92.1 Sequelae of fracture of arm	0.000	0.995	0.005
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.005	0.995	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.995	0.004
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.995	0.004
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.996	0.004
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.996	0.004
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.996	0.004
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.996	0.004
T92.0 Sequelae of open wound of upper limb	0.000	0.996	0.004
E05.5 Thyroid crisis or storm	0.000	0.996	0.004
E05.4 Thyrotoxicosis factitia	0.000	0.996	0.004
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.996	0.004
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.996	0.004
M48.04 Spinal stenosis (Thoracic region)	0.000	0.996	0.004
E05.8 Other thyrotoxicosis	0.000	0.996	0.004
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.996	0.004
M48 Other spondylopathies	0.000	0.996	0.004
K57.3 Diverticular disease of large intestine without perforation or abscess	0.004	0.996	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.996	0.004
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.996	0.004
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.996	0.004
Z63.4 Disappearance and death of family member	0.004	0.996	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.004	0.996	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.996	0.004
F32.3 Severe depressive episode with psychotic symptoms	0.004	0.996	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.996	0.003
T92 Sequelae of injuries of upper limb	0.000	0.996	0.004
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.997	0.003
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.997	0.003
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.997	0.003
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.997	0.003
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.997	0.003
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.997	0.003
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M48.8 Other specified spondylopathies	0.000	0.997	0.003
M48.4 Fatigue fracture of vertebra	0.000	0.997	0.003
M48.3 Traumatic spondylopathy	0.000	0.997	0.003
M48.2 Kissing spine	0.000	0.997	0.003
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.997	0.003
L73.2 Hidradenitis suppurativa	0.000	0.997	0.003
K75.0 Abscess of liver	0.000	0.997	0.003
S32 Fracture of lumbar spine and pelvis	0.000	0.997	0.003
S32.30 Fracture of ilium (closed)	0.000	0.997	0.003
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.997	0.003
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.997	0.003
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.997	0.003
E14.3 With ophthalmic complications	0.000	0.997	0.003
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.997	0.003
S32.3 Fracture of ilium	0.000	0.997	0.003
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.997	0.003
C92.0 Acute myeloid leukaemia	0.000	0.997	0.003
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
Z84.8 Family history of other specified conditions	0.003	0.997	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.997	0.003
F81.9 Developmental disorder of scholastic skills, unspecified	0.003	0.997	0.000
K75.4 Autoimmune hepatitis	0.000	0.997	0.003
M48.9 Spondylopathy, unspecified	0.000	0.997	0.003
K75 Other inflammatory liver diseases	0.000	0.997	0.003
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.997	0.003
I95.2 Hypotension due to drugs	0.003	0.997	0.000
M15.1 Heberden's nodes (with arthropathy)	0.003	0.997	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.997	0.002
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.997	0.002
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.997	0.002
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.997	0.002
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.997	0.002
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.997	0.002
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.997	0.002
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.997	0.002
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.997	0.002
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.997	0.002
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.997	0.002
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.997	0.002
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.997	0.002
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.997	0.002
M48.29 Kissing spine (Site unspecified)	0.000	0.997	0.002
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.27 Kissing spine (Lumbosacral region)	0.000	0.997	0.002
M48.26 Kissing spine (Lumbar region)	0.000	0.997	0.002
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.997	0.002
M48.24 Kissing spine (Thoracic region)	0.000	0.997	0.002
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.997	0.002
M48.22 Kissing spine (Cervical region)	0.000	0.997	0.002
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.997	0.002
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.997	0.002
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.997	0.002
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.997	0.002
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.997	0.002
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.997	0.002
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.997	0.002
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.997	0.002
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.997	0.002
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.997	0.002
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.997	0.002
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.997	0.002
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.997	0.002
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.997	0.002
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.997	0.002
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.997	0.002
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.997	0.002
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.997	0.002
D35.2 Pituitary gland	0.003	0.997	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.000	0.997	0.002
C91.4 Hairy-cell leukaemia	0.000	0.997	0.002
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.000	0.998	0.002
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
K52.3 Indeterminate colitis	0.002	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
S32.1 Fracture of sacrum	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.998	0.002
M48.92 Spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
M67.43 Ganglion, wrist	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M48.94 Spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
M48.02 Spinal stenosis (Cervical region)	0.000	0.998	0.002
C91.9 Lymphoid leukaemia, unspecified	0.000	0.998	0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.998	0.002
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
N91.2 Amenorrhoea, unspecified	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
K81.0 Acute cholecystitis	0.000	0.998	0.002
K52.0 Gastro-enteritis and colitis due to radiation	0.002	0.998	0.000
L73.9 Follicular disorder, unspecified	0.000	0.998	0.002
C91 Lymphoid leukaemia	0.000	0.998	0.002
F81 Specific developmental disorders of scholastic skills	0.002	0.998	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
M48.99 Spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
C91.5 Adult T-cell leukaemia	0.000	0.998	0.002
C92.4 Acute promyelocytic leukaemia	0.000	0.998	0.002
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
C92 Myeloid leukaemia	0.000	0.998	0.002
S32.21 Fracture of coccyx (open)	0.000	0.998	0.002
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.000	0.998	0.002
M15 Polyarthrosis	0.002	0.998	0.000
D36 Benign neoplasm of other and unspecified sites	0.002	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
L73 Other follicular disorders	0.000	0.998	0.002
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.002	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.000	0.998	0.002
E10.9 Without complications	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
M15.8 Other polyarthrosis	0.002	0.998	0.000
S32.5 Fracture of pubis	0.000	0.998	0.002
E10.1 With ketoacidosis	0.000	0.998	0.002
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.002
D36.9 Benign neoplasm of unspecified site	0.002	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
M15.3 Secondary multiple arthrosis	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.998	0.002
C92.5 Acute myelomonocytic leukaemia	0.000	0.998	0.002
Z59.0 Homelessness	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.002	0.998	0.000
Z63.3 Absence of family member	0.002	0.998	0.000
Z63.2 Inadequate family support	0.002	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.998	0.002
C91.7 Other lymphoid leukaemia	0.000	0.998	0.002
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.998	0.002
C91.3 Prolymphocytic leukaemia	0.000	0.998	0.002
C91.2 Subacute lymphocytic leukaemia	0.000	0.998	0.002
F81.8 Other developmental disorders of scholastic skills	0.002	0.998	0.000
F81.3 Mixed disorder of scholastic skills	0.002	0.998	0.000
F81.2 Specific disorder of arithmetical skills	0.002	0.998	0.000
F81.1 Specific spelling disorder	0.002	0.998	0.000
F81.0 Specific reading disorder	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
L73.1 Pseudofolliculitis barbae	0.000	0.998	0.002
K52 Other non-infective gastro-enteritis and colitis	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.002	0.998	0.000
C81.1 Nodular sclerosis	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.998	0.002
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.998	0.002
C92.3 Myeloid sarcoma	0.000	0.998	0.002
F80.1 Expressive language disorder	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.000	0.998	0.002
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.002
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
M15.0 Primary generalised (osteo)arthrosis	0.002	0.998	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
C95.9 Leukaemia, unspecified	0.000	0.998	0.002
S81.0 Open wound of knee	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
C92.9 Myeloid leukaemia, unspecified	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.000	0.998	0.002
L73.0 Acne keloid	0.000	0.998	0.002
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
M15.4 Erosive (osteo)arthrosis	0.002	0.998	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.001
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
M15.9 Polyarthrosis, unspecified	0.002	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.998	0.001
I20.8 Other forms of angina pectoris	0.000	0.998	0.002
Z58.9 Problem related to physical environment, unspecified	0.001	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.001	0.998	0.000
Z58.4 Exposure to radiation	0.001	0.998	0.000
Z58.3 Exposure to soil pollution	0.001	0.998	0.000
Z58.2 Exposure to water pollution	0.001	0.998	0.000
Z58.0 Exposure to noise	0.001	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.000	0.998	0.002
C92.2 Subacute myeloid leukaemia	0.000	0.998	0.001
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
I67 Other cerebrovascular diseases	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
Z61.6 Problems related to alleged physical abuse of child	0.001	0.998	0.000
F99 Mental disorder, not otherwise specified	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.998	0.001
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.998	0.002
F80.2 Receptive language disorder	0.001	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.002
K22.4 Dyskinesia of oesophagus	0.002	0.998	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.001	0.998	0.000
Z58.1 Exposure to air pollution	0.001	0.998	0.000
F80-F89 Disorders of psychological development	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.000	0.998	0.001
Z56.7 Other and unspecified problems related to employment	0.001	0.998	0.000
Z59.7 Insufficient social insurance and welfare support	0.001	0.998	0.000
Z59.6 Low income	0.001	0.998	0.000
Z59.5 Extreme poverty	0.001	0.998	0.000
Z59.4 Lack of adequate food	0.001	0.998	0.000
Z59.3 Problems related to living in residential institution	0.001	0.998	0.000
C95 Leukaemia of unspecified cell type	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
F84 Pervasive developmental disorders	0.001	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.998	0.001
C82.5 Diffuse follicle centre lymphoma	0.000	0.998	0.001
K52.8 Other specified non-infective gastro-enteritis and colitis	0.002	0.998	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.001	0.998	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.001	0.998	0.000
D86.3 Sarcoidosis of skin	0.000	0.998	0.001
Z56.0 Unemployment, unspecified	0.001	0.998	0.000
Z62 Other problems related to upbringing	0.001	0.998	0.000
Z55 Problems related to education and literacy	0.001	0.998	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.998	0.001
F80.9 Developmental disorder of speech and language, unspecified	0.001	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.001	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.001	0.998	0.000
F80.0 Specific speech articulation disorder	0.001	0.998	0.000
Y45.2 Propionic acid derivatives	0.000	0.998	0.001
Z64.4 Discord with counsellors	0.001	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.001	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.001	0.998	0.000
Z64.1 Problems related to multiparity	0.001	0.998	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
C34.0 Main bronchus	0.001	0.999	0.000
C92.7 Other myeloid leukaemia	0.000	0.999	0.001
Z56.5 Uncongenial work	0.001	0.999	0.000
Z56.4 Discord with boss and workmates	0.001	0.999	0.000
Z56.2 Threat of job loss	0.001	0.999	0.000
Z56.1 Change of job	0.001	0.999	0.000
Z61.9 Negative life events in childhood, unspecified	0.001	0.999	0.000
Z61.8 Other negative life events in childhood	0.001	0.999	0.000
Z61.7 Personal frightening experience in childhood	0.001	0.999	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.001	0.999	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.001	0.999	0.000
Z61.2 Altered pattern of family relationships in childhood	0.001	0.999	0.000
Z61.1 Removal from home in childhood	0.001	0.999	0.000
Z61.0 Loss of love relationship in childhood	0.001	0.999	0.000
D86 Sarcoidosis	0.000	0.999	0.001
J46 Status asthmaticus	0.000	0.999	0.001
F84.5 Asperger's syndrome	0.001	0.999	0.000
H74.4 Polyp of middle ear	0.000	0.999	0.001
J37.0 Chronic laryngitis	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
Z59.1 Inadequate housing	0.001	0.999	0.000
Z65 Problems related to other psychosocial circumstances	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.999	0.001
F84.0 Childhood autism	0.001	0.999	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.999	0.001
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.999	0.001
I67.5 Moyamoya disease	0.000	0.999	0.001
I67.4 Hypertensive encephalopathy	0.000	0.999	0.001
I67.3 Progressive vascular leukoencephalopathy	0.000	0.999	0.001
L73.8 Other specified follicular disorders	0.000	0.999	0.001
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.999	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.999	0.001
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.999	0.000
Z63.5 Disruption of family by separation and divorce	0.001	0.999	0.000
C81 Hodgkin's disease	0.001	0.999	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.999	0.001
D36.7 Other specified sites	0.001	0.999	0.000
O32.2 Maternal care for transverse and oblique lie	0.001	0.999	0.000
F89 Unspecified disorder of psychological development	0.001	0.999	0.000
F88 Other disorders of psychological development	0.001	0.999	0.000
F83 Mixed specific developmental disorders	0.001	0.999	0.000
F82 Specific developmental disorder of motor function	0.001	0.999	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.001	0.999	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.999	0.001
C95.7 Other leukaemia of unspecified cell type	0.000	0.999	0.001
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.999	0.001
C95.0 Acute leukaemia of unspecified cell type	0.000	0.999	0.001
D21.2 Connective and other soft tissue of lower limb, including hip	0.001	0.999	0.000
F84.9 Pervasive developmental disorder, unspecified	0.001	0.999	0.000
F84.8 Other pervasive developmental disorders	0.001	0.999	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.001	0.999	0.000
F84.3 Other childhood disintegrative disorder	0.001	0.999	0.000
F84.2 Rett's syndrome	0.001	0.999	0.000
F84.1 Atypical autism	0.001	0.999	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.999	0.001
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.999	0.001
Y43.4 Immunosuppressive agents	0.000	0.999	0.001
M15.99 Polyosteoarthritis, unspecified	0.001	0.999	0.000
C81.2 Mixed cellularity	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.001	0.999	0.000
Z55.8 Other problems relating to education and literacy	0.001	0.999	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.001	0.999	0.000
Z55.3 Underachievement in school	0.001	0.999	0.000
Z55.2 Failed examinations	0.001	0.999	0.000
Z55.1 Schooling unavailable and unattainable	0.001	0.999	0.000
Z55.0 Illiteracy and low-level literacy	0.001	0.999	0.000
Z62.9 Problem related to upbringing, unspecified	0.001	0.999	0.000
Z62.8 Other specified problems related to upbringing	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations