TreeWAS – Variant ID: rs12555078

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13 Obstructive and reflux uropathy	0.203	0.797	0.000
N13.3 Other and unspecified hydronephrosis	0.190	0.810	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.189	0.810	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.188	0.812	0.000
N13.4 Hydroureter	0.185	0.815	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.172	0.828	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.168	0.832	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.164	0.835	0.000
N13.8 Other obstructive and reflux uropathy	0.164	0.836	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.146	0.854	0.000
N10-N16 Renal tubulo-interstitial diseases	0.120	0.880	0.000
N13.6 Pyonephrosis	0.116	0.884	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.109	0.891	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.086	0.913	0.000
N15 Other renal tubulo-interstitial diseases	0.086	0.913	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.086	0.913	0.000
N10 Acute tubulo-interstitial nephritis	0.081	0.919	0.000
N11 Chronic tubulo-interstitial nephritis	0.078	0.922	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.062	0.938	0.000
N14.3 Nephropathy induced by heavy metals	0.062	0.938	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.062	0.938	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.062	0.938	0.000
N14.0 Analgesic nephropathy	0.062	0.938	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.062	0.938	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.062	0.938	0.000
N15.1 Renal and perinephric abscess	0.062	0.938	0.000
N15.0 Balkan nephropathy	0.062	0.938	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.062	0.938	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.062	0.938	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.062	0.938	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.062	0.938	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.062	0.938	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.062	0.938	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.062	0.938	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.056	0.944	0.000
N11.1 Chronic obstructive pyelonephritis	0.056	0.944	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.056	0.944	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.047	0.953	0.000
L40.5 Arthropathic psoriasis	0.021	0.979	0.000
L40 Psoriasis	0.016	0.984	0.000
L40.9 Psoriasis, unspecified	0.014	0.986	0.000
L40.8 Other psoriasis	0.012	0.988	0.000
L40.4 Guttate psoriasis	0.012	0.988	0.000
L40.3 Pustulosis palmaris et plantaris	0.012	0.988	0.000
L40.2 Acrodermatitis continua	0.012	0.988	0.000
L40.1 Generalised pustular psoriasis	0.012	0.988	0.000
L40.0 Psoriasis vulgaris	0.011	0.989	0.000
N86 Erosion and ectropion of cervix uteri	0.011	0.989	0.000
L40-L45 Papulosquamous disorders	0.009	0.991	0.000
L43 Lichen planus	0.008	0.992	0.000
L42 Pityriasis rosea	0.008	0.992	0.000
L44 Other papulosquamous disorders	0.007	0.993	0.000
L41 Parapsoriasis	0.007	0.993	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.007	0.993	0.000
R53 Malaise and fatigue	0.000	0.993	0.007
L43.9 Lichen planus, unspecified	0.007	0.993	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.994	0.006
L43.3 Subacute (active) lichen planus	0.006	0.994	0.000
L43.2 Lichenoid drug reaction	0.006	0.994	0.000
L43.1 Bullous lichen planus	0.006	0.994	0.000
L43.0 Hypertrophic lichen planus	0.006	0.994	0.000
L43.8 Other lichen planus	0.005	0.994	0.000
L41.9 Parapsoriasis, unspecified	0.005	0.995	0.000
L41.8 Other parapsoriasis	0.005	0.995	0.000
L41.5 Retiform parapsoriasis	0.005	0.995	0.000
L41.4 Large plaque parapsoriasis	0.005	0.995	0.000
L41.3 Small plaque parapsoriasis	0.005	0.995	0.000
L41.2 Lymphomatoid papulosis	0.005	0.995	0.000
L41.1 Pityriasis lichenoides chronica	0.005	0.995	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.005	0.995	0.000
L44.9 Papulosquamous disorder, unspecified	0.005	0.995	0.000
L44.8 Other specified papulosquamous disorders	0.005	0.995	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.005	0.995	0.000
L44.3 Lichen ruber moniliformis	0.005	0.995	0.000
L44.2 Lichen striatus	0.005	0.995	0.000
L44.1 Lichen nitidus	0.005	0.995	0.000
L44.0 Pityriasis rubra pilaris	0.005	0.995	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.995	0.005
C79 Secondary malignant neoplasm of other sites	0.000	0.995	0.005
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.995	0.005
C78.0 Secondary malignant neoplasm of lung	0.000	0.995	0.005
C79.2 Secondary malignant neoplasm of skin	0.000	0.996	0.004
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.996	0.004
N80.3 Endometriosis of pelvic peritoneum	0.004	0.996	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.996	0.004
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.996	0.004
M25.78 Osteophyte (Other)	0.000	0.996	0.004
Z03.8 Observation for other suspected diseases and conditions	0.004	0.996	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.996	0.004
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.996	0.004
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.996	0.004
C32.0 Glottis	0.000	0.996	0.004
C78.7 Secondary malignant neoplasm of liver	0.000	0.996	0.004
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.996	0.004
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.996	0.004
C80.9 Malignant neoplasm, unspecified	0.000	0.996	0.004
C32 Malignant neoplasm of larynx	0.000	0.996	0.004
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.997	0.003
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.997	0.003
C80 Malignant neoplasm without specification of site	0.000	0.997	0.003
N93.0 Postcoital and contact bleeding	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.000	0.997	0.003
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.997	0.003
N80 Endometriosis	0.003	0.997	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.997	0.003
I44.7 Left bundle-branch block, unspecified	0.003	0.997	0.000
N80.5 Endometriosis of intestine	0.003	0.997	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.997	0.003
O02.1 Missed abortion	0.000	0.997	0.003
C34 Malignant neoplasm of bronchus and lung	0.000	0.997	0.003
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.997	0.003
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.997	0.003
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.997	0.003
N80.8 Other endometriosis	0.003	0.997	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.997	0.003
C32.1 Supraglottis	0.000	0.997	0.003
C34.3 Lower lobe, bronchus or lung	0.000	0.997	0.003
N80.9 Endometriosis, unspecified	0.003	0.997	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.000	0.997	0.003
C32.3 Laryngeal cartilage	0.000	0.997	0.003
C32.2 Subglottis	0.000	0.997	0.003
N80.2 Endometriosis of Fallopian tube	0.003	0.997	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.997	0.003
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.997	0.003
M25.71 Osteophyte (Shoulder region)	0.000	0.997	0.003
C34.0 Main bronchus	0.000	0.997	0.003
N80.6 Endometriosis in cutaneous scar	0.003	0.997	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.997	0.003
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
C34.9 Bronchus or lung, unspecified	0.000	0.997	0.003
C34.8 Overlapping lesion of bronchus and lung	0.000	0.997	0.002
E86 Volume depletion	0.000	0.997	0.003
M25.7 Osteophyte	0.000	0.997	0.003
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.997	0.003
Z03.3 Observation for suspected nervous system disorder	0.002	0.998	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.998	0.002
C76.7 Other ill-defined sites	0.000	0.998	0.002
C76.5 Lower limb	0.000	0.998	0.002
C76.4 Upper limb	0.000	0.998	0.002
C76.3 Pelvis	0.000	0.998	0.002
C76.2 Abdomen	0.000	0.998	0.002
C76.1 Thorax	0.000	0.998	0.002
C76.0 Head, face and neck	0.000	0.998	0.002
N80.0 Endometriosis of uterus	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.002	0.998	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.998	0.002
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.998	0.002
C31 Malignant neoplasm of accessory sinuses	0.000	0.998	0.002
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.998	0.002
C37 Malignant neoplasm of thymus	0.000	0.998	0.002
C33 Malignant neoplasm of trachea	0.000	0.998	0.002
Z03.4 Observation for suspected myocardial infarction	0.002	0.998	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.000	0.998	0.002
N80.1 Endometriosis of ovary	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.998	0.002
M25.73 Osteophyte (Forearm)	0.000	0.998	0.002
M25.70 Osteophyte (Multiple sites)	0.000	0.998	0.002
C77.4 Inguinal and lower limb lymph nodes	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.998	0.002
H65.0 Acute serous otitis media	0.002	0.998	0.000
Z03.0 Observation for suspected tuberculosis	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
C30.1 Middle ear	0.000	0.998	0.002
C30.0 Nasal cavity	0.000	0.998	0.002
C31.9 Accessory sinus, unspecified	0.000	0.998	0.002
C31.8 Overlapping lesion of accessory sinuses	0.000	0.998	0.002
C31.3 Sphenoidal sinus	0.000	0.998	0.002
C31.2 Frontal sinus	0.000	0.998	0.002
C31.1 Ethmoidal sinus	0.000	0.998	0.002
C31.0 Maxillary sinus	0.000	0.998	0.002
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.998	0.002
C38.4 Pleura	0.000	0.998	0.002
C38.3 Mediastinum, part unspecified	0.000	0.998	0.002
C38.2 Posterior mediastinum	0.000	0.998	0.002
C38.1 Anterior mediastinum	0.000	0.998	0.002
C38.0 Heart	0.000	0.998	0.002
C39.9 Ill-defined sites within the respiratory system	0.000	0.998	0.002
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.998	0.002
C39.0 Upper respiratory tract, part unspecified	0.000	0.998	0.002
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
O63.1 Prolonged second stage (of labour)	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.998	0.002
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
N20.1 Calculus of ureter	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
C77.3 Axillary and upper limb lymph nodes	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
M25.72 Osteophyte (Upper arm)	0.000	0.998	0.001
Z03.2 Observation for suspected mental and behavioural disorders	0.001	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
Y40.0 Penicillins	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.000	0.998	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
B25.9 Cytomegaloviral disease, unspecified	0.001	0.998	0.000
H65.2 Chronic serous otitis media	0.001	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.998	0.000
K04.5 Chronic apical periodontitis	0.000	0.998	0.002
R59.1 Generalised enlarged lymph nodes	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.000	0.998	0.001
Y57.7 Vitamins, not elsewhere classified	0.000	0.998	0.001
Y57.6 Other diagnostic agents	0.000	0.998	0.001
Y57.4 Pharmaceutical excipients	0.000	0.998	0.001
Y57.3 Alcohol deterrents	0.000	0.998	0.001
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
Y57.1 Lipotropic drugs	0.000	0.998	0.001
Y57.0 Appetite depressants [anorectics]	0.000	0.998	0.001
L53.9 Erythematous condition, unspecified	0.000	0.998	0.001
Z95.0 Presence of cardiac pacemaker	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.999	0.001
N90.4 Leukoplakia of vulva	0.001	0.999	0.000
Z03.1 Observation for suspected malignant neoplasm	0.001	0.999	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
X51.9 Unspecified place	0.001	0.999	0.000
Y43.3 Other antineoplastic drugs	0.000	0.999	0.001
O02 Other abnormal products of conception	0.000	0.999	0.001
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
B25.8 Other cytomegaloviral diseases	0.001	0.999	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
N92.6 Irregular menstruation, unspecified	0.001	0.999	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.999	0.001
Y43.1 Antineoplastic antimetabolites	0.000	0.999	0.001
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.999	0.001
I08.1 Disorders of both mitral and tricuspid valves	0.001	0.999	0.000
N90.6 Hypertrophy of vulva	0.001	0.999	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.001	0.999	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.999	0.001
O02.8 Other specified abnormal products of conception	0.000	0.999	0.001
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
Y41.5 Antiviral drugs	0.000	0.999	0.001
Y41.4 Anthelminthics	0.000	0.999	0.001
Y41.3 Other antiprotozoal drugs	0.000	0.999	0.001
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
Y41.1 Antimycobacterial drugs	0.000	0.999	0.001
Y41.0 Sulphonamides	0.000	0.999	0.001
B25 Cytomegaloviral disease	0.001	0.999	0.000
I65.2 Occlusion and stenosis of carotid artery	0.001	0.999	0.000
Y43 Primarily systemic agents	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.999	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
H16.0 Corneal ulcer	0.001	0.999	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.999	0.001
O73.0 Retained placenta, without haemorrhage	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
Y42.4 Oral contraceptives	0.000	0.999	0.001
Y42.2 Antithyroid drugs	0.000	0.999	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.999	0.001
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
N28 Other disorders of kidney and ureter, not elsewhere classified	0.001	0.999	0.000
R18 Ascites	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
Z39.0 Care and examination immediately after delivery	0.001	0.999	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.999	0.000
B25.2 Cytomegaloviral pancreatitis	0.001	0.999	0.000
B25.1 Cytomegaloviral hepatitis	0.001	0.999	0.000
B25.0 Cytomegaloviral pneumonitis	0.001	0.999	0.000
N28.0 Ischaemia and infarction of kidney	0.001	0.999	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
J92.9 Pleural plaque without asbestos	0.000	0.999	0.001
M20.0 Deformity of finger(s)	0.000	0.999	0.001
N92.1 Excessive and frequent menstruation with irregular cycle	0.001	0.999	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.999	0.001
Y43.9 Primarily systemic agent, unspecified	0.000	0.999	0.001
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.999	0.001
Y43.6 Enzymes, not elsewhere classified	0.000	0.999	0.001
Y43.5 Acidifying and alkalising agents	0.000	0.999	0.001
Y43.2 Antineoplastic natural products	0.000	0.999	0.001
Y54.3 Benzothiadiazine derivatives	0.000	0.999	0.001
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.001	0.999	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.999	0.001
S42.40 Fracture of lower end of humerus (closed)	0.000	0.999	0.001
C22.9 Liver, unspecified	0.000	0.999	0.001
C71.2 Temporal lobe	0.000	0.999	0.001
K04.7 Periapical abscess without sinus	0.000	0.999	0.001
M07.3 Other psoriatic arthropathies	0.001	0.999	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.001	0.999	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.999	0.000
S42.00 Fracture of clavicle (closed)	0.001	0.999	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
I08.9 Multiple valve disease, unspecified	0.001	0.999	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.999	0.001
M94.8 Other specified disorders of cartilage	0.000	0.999	0.001
Y43.0 Antiallergic and antiemetic drugs	0.000	0.999	0.001
M83.12 Senile osteomalacia (Upper arm)	0.001	0.999	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.999	0.001
J35.0 Chronic tonsillitis	0.001	0.999	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.999	0.001
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
M07.38 Other psoriatic arthropathies (Other)	0.001	0.999	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.001	0.999	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.001	0.999	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.001	0.999	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.001	0.999	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.001	0.999	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.001	0.999	0.000
B34.4 Papovirus infection, unspecified	0.001	0.999	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.999	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
S61.8 Open wound of other parts of wrist and hand	0.000	0.999	0.001
Y42.7 Androgens and anabolic congeners	0.000	0.999	0.001
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.999	0.001
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.999	0.001
H65-H75 Diseases of middle ear and mastoid	0.001	0.999	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.999	0.001
M94.26 Chondromalacia (Lower leg)	0.000	0.999	0.001
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.999	0.001
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.999	0.001
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.999	0.001
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.999	0.001
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.999	0.001
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.999	0.001
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.999	0.001
H16.9 Keratitis, unspecified	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
N76.2 Acute vulvitis	0.000	0.999	0.001
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.001	0.999	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.999	0.001
H43.1 Vitreous haemorrhage	0.000	0.999	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
R44.3 Hallucinations, unspecified	0.001	0.999	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.999	0.001
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.999	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.999	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.999	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.000	0.999	0.001
H16.2 Keratoconjunctivitis	0.001	0.999	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
K04.6 Periapical abscess with sinus	0.000	0.999	0.001
K31.9 Disease of stomach and duodenum, unspecified	0.001	0.999	0.000
N04.9 Unspecified	0.001	0.999	0.000
N28.8 Other specified disorders of kidney and ureter	0.001	0.999	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.001	0.999	0.000
N90.5 Atrophy of vulva	0.001	0.999	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.001	0.999	0.000
I08 Multiple valve diseases	0.001	0.999	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.999	0.001
H66.3 Other chronic suppurative otitis media	0.001	0.999	0.000
N90.3 Dysplasia of vulva, unspecified	0.001	0.999	0.000
X62.9 Unspecified place	0.001	0.999	0.000
Y54.5 Other diuretics	0.000	0.999	0.001
H70 Mastoiditis and related conditions	0.001	0.999	0.000
N93 Other abnormal uterine and vaginal bleeding	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.000	0.999	0.001
Y58 Bacterial vaccines	0.000	0.999	0.001
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.999	0.001
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.999	0.001
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.999	0.001
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.999	0.001
Y40 Systemic antibiotics	0.000	0.999	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.999	0.001
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000
H70.2 Petrositis	0.001	0.999	0.000
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
I87.8 Other specified disorders of veins	0.000	0.999	0.001
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.001	0.999	0.000
N90.1 Moderate vulvar dysplasia	0.001	0.999	0.000
N90.0 Mild vulvar dysplasia	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.999	0.001
R68.8 Other specified general symptoms and signs	0.000	0.999	0.001
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
Y40.6 Rifamycins	0.000	0.999	0.001
Y40.5 Aminoglycosides	0.000	0.999	0.001
Y40.4 Tetracyclines	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.000	0.999	0.001
Y43.4 Immunosuppressive agents	0.000	0.999	0.001
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.999	0.001
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.999	0.001
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.999	0.001
Y47.4 Bromine compounds	0.000	0.999	0.001
Y47.3 Paraldehyde	0.000	0.999	0.001
Y47.2 Chloral derivatives	0.000	0.999	0.001
Y47.1 Benzodiazepines	0.000	0.999	0.001
Y47.0 Barbiturates, not elsewhere classified	0.000	0.999	0.001
Y50.9 Central nervous system stimulant, unspecified	0.000	0.999	0.001
Y50.8 Other central nervous system stimulants	0.000	0.999	0.001
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.999	0.001
Y50.1 Opioid receptor antagonists	0.000	0.999	0.001
Y50.0 Analeptics	0.000	0.999	0.001
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.999	0.001
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.999	0.001
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.999	0.001
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.999	0.001
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.999	0.001
Y51.0 Anticholinesterase agents	0.000	0.999	0.001
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.999	0.001
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
Y53.7 Emetics	0.000	0.999	0.001
Y53.6 Antidiarrhoeal drugs	0.000	0.999	0.001
Y53.5 Digestants	0.000	0.999	0.001
Y53.4 Other laxatives	0.000	0.999	0.001
Y53.3 Saline and osmotic laxatives	0.000	0.999	0.001
Y53.2 Stimulant laxatives	0.000	0.999	0.001
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
Y53.0 Histamine H2-receptor antagonists	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.000	0.999	0.001
Y54.7 Agents affecting calcification	0.000	0.999	0.001
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.999	0.001
Y54.0 Mineralocorticoids	0.000	0.999	0.001
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
Y55.5 Anticommon cold drugs	0.000	0.999	0.001
Y55.4 Expectorants	0.000	0.999	0.001
Y55.3 Antitussives	0.000	0.999	0.001
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.999	0.001
Y55.0 Oxytocic drugs	0.000	0.999	0.001
Y58.9 Other and unspecified bacterial vaccines	0.000	0.999	0.001
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.999	0.001
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.999	0.001
Y58.5 Diphtheria vaccine	0.000	0.999	0.001
Y58.4 Tetanus vaccine	0.000	0.999	0.001
Y58.3 Plague vaccine	0.000	0.999	0.001
Y58.2 Cholera vaccine	0.000	0.999	0.001
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.999	0.001
Y58.0 BCG vaccine	0.000	0.999	0.001
Y59.9 Vaccine or biological substance, unspecified	0.000	0.999	0.001
Y59.8 Other specified vaccines and biological substances	0.000	0.999	0.001
Y59.3 Immunoglobulin	0.000	0.999	0.001
Y59.2 Protozoal vaccines	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations