TreeWAS – Variant ID: rs12587311

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H60.9 Otitis externa, unspecified	0.174	0.826	0.000
H60 Otitis externa	0.168	0.832	0.000
H60.1 Cellulitis of external ear	0.151	0.849	0.000
H60-H62 Diseases of external ear	0.143	0.857	0.000
H60.5 Acute otitis externa, non-infective	0.136	0.863	0.000
H61 Other disorders of external ear	0.136	0.864	0.000
H60.2 Malignant otitis externa	0.135	0.865	0.000
H60.8 Other otitis externa	0.133	0.867	0.000
H61.8 Other specified disorders of external ear	0.128	0.871	0.000
H60.0 Abscess of external ear	0.126	0.874	0.000
H61.0 Perichondritis of external ear	0.116	0.884	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.115	0.885	0.000
H61.3 Acquired stenosis of external ear canal	0.113	0.887	0.000
H60.3 Other infective otitis externa	0.106	0.894	0.000
H60.4 Cholesteatoma of external ear	0.105	0.895	0.000
H61.9 Disorder of external ear, unspecified	0.104	0.896	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.898	0.102
H61.1 Non-infective disorders of pinna	0.102	0.898	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.094	0.905	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.082	0.918	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.082	0.918	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.082	0.918	0.000
H62.2 Otitis externa in mycoses	0.082	0.918	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.082	0.918	0.000
F32 Depressive episode	0.000	0.936	0.064
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.943	0.057
F32.1 Moderate depressive episode	0.000	0.946	0.054
F32.0 Mild depressive episode	0.000	0.947	0.053
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.050	0.950	0.000
F32.8 Other depressive episodes	0.000	0.956	0.044
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.957	0.043
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.978	0.022
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.979	0.021
H61.2 Impacted cerumen	0.019	0.980	0.000
C34.1 Upper lobe, bronchus or lung	0.018	0.982	0.000
Y44.2 Anticoagulants	0.018	0.982	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.018	0.982	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.985	0.015
N95.2 Postmenopausal atrophic vaginitis	0.015	0.985	0.000
C34 Malignant neoplasm of bronchus and lung	0.014	0.986	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.987	0.013
R29.0 Tetany	0.013	0.987	0.000
R26.0 Ataxic gait	0.013	0.987	0.000
R29.4 Clicking hip	0.013	0.987	0.000
R29.3 Abnormal posture	0.013	0.987	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.013	0.987	0.000
C34.3 Lower lobe, bronchus or lung	0.013	0.987	0.000
C32 Malignant neoplasm of larynx	0.013	0.987	0.000
C32.9 Larynx, unspecified	0.012	0.987	0.000
R29.2 Abnormal reflex	0.012	0.988	0.000
R26 Abnormalities of gait and mobility	0.012	0.988	0.000
Z50.1 Other physical therapy	0.011	0.989	0.000
C31 Malignant neoplasm of accessory sinuses	0.011	0.989	0.000
R26.3 Immobility	0.010	0.989	0.000
R29.1 Meningismus	0.010	0.990	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.010	0.990	0.000
C37 Malignant neoplasm of thymus	0.010	0.990	0.000
C32.3 Laryngeal cartilage	0.010	0.990	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.010	0.990	0.000
C32.1 Supraglottis	0.010	0.990	0.000
C34.2 Middle lobe, bronchus or lung	0.010	0.990	0.000
C33 Malignant neoplasm of trachea	0.010	0.990	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.010	0.990	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.990	0.010
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.009	0.990	0.000
C32.8 Overlapping lesion of larynx	0.009	0.991	0.000
C32.2 Subglottis	0.009	0.991	0.000
C31.0 Maxillary sinus	0.009	0.991	0.000
O63.0 Prolonged first stage (of labour)	0.009	0.991	0.000
C38.4 Pleura	0.009	0.991	0.000
R26.1 Paralytic gait	0.009	0.991	0.000
C32.0 Glottis	0.009	0.991	0.000
R29.6 Tendency to fall, not elsewhere classified	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.991	0.000
C34.8 Overlapping lesion of bronchus and lung	0.008	0.992	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.008	0.992	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.008	0.992	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.008	0.992	0.000
C31.9 Accessory sinus, unspecified	0.008	0.992	0.000
C31.8 Overlapping lesion of accessory sinuses	0.008	0.992	0.000
C31.3 Sphenoidal sinus	0.008	0.992	0.000
C31.2 Frontal sinus	0.008	0.992	0.000
C31.1 Ethmoidal sinus	0.008	0.992	0.000
T93 Sequelae of injuries of lower limb	0.000	0.992	0.008
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.008	0.992	0.000
C38.2 Posterior mediastinum	0.008	0.992	0.000
C38.1 Anterior mediastinum	0.008	0.992	0.000
C38.0 Heart	0.008	0.992	0.000
C30.0 Nasal cavity	0.008	0.992	0.000
F30-F39 Mood [affective] disorders	0.000	0.993	0.007
C30.1 Middle ear	0.007	0.993	0.000
C38.3 Mediastinum, part unspecified	0.007	0.993	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.993	0.007
C39.9 Ill-defined sites within the respiratory system	0.007	0.993	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.007	0.993	0.000
C39.0 Upper respiratory tract, part unspecified	0.007	0.993	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.993	0.007
R01.0 Benign and innocent cardiac murmurs	0.000	0.993	0.007
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.993	0.007
T93.0 Sequelae of open wound of lower limb	0.000	0.993	0.007
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.993	0.007
C34.9 Bronchus or lung, unspecified	0.007	0.993	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.993	0.007
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.994	0.000
Y44.7 Plasma substitutes	0.006	0.994	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.994	0.000
Y44.6 Natural blood and blood products	0.006	0.994	0.000
F33 Recurrent depressive disorder	0.000	0.994	0.006
R15 Faecal incontinence	0.000	0.994	0.006
R01 Cardiac murmurs and other cardiac sounds	0.000	0.994	0.006
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.994	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.994	0.006
Chapter VIII Diseases of the ear and mastoid process	0.006	0.994	0.000
G45.4 Transient global amnesia	0.000	0.994	0.006
Y44.5 Thrombolytic drugs	0.005	0.994	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.994	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.994	0.005
C22.9 Liver, unspecified	0.005	0.995	0.000
T93.1 Sequelae of fracture of femur	0.000	0.995	0.005
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.995	0.005
F38 Other mood [affective] disorders	0.000	0.995	0.005
T93.2 Sequelae of other fractures of lower limb	0.000	0.995	0.005
F34 Persistent mood [affective] disorders	0.000	0.995	0.005
M47.86 Other spondylosis (Lumbar region)	0.005	0.995	0.000
C34.0 Main bronchus	0.005	0.995	0.000
D26.0 Cervix uteri	0.005	0.995	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.995	0.005
F39 Unspecified mood [affective] disorder	0.000	0.995	0.005
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.995	0.005
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.995	0.005
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.005	0.995	0.000
R01.2 Other cardiac sounds	0.000	0.995	0.004
I31.3 Pericardial effusion (noninflammatory)	0.000	0.995	0.005
F33.8 Other recurrent depressive disorders	0.000	0.996	0.004
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.996	0.004
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
F30 Manic episode	0.000	0.996	0.004
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.996	0.004
R27 Other lack of coordination	0.004	0.996	0.000
F38.0 Other single mood [affective] disorders	0.000	0.996	0.004
F38.1 Other recurrent mood [affective] disorders	0.000	0.996	0.004
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.004	0.996	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.996	0.004
F34.8 Other persistent mood [affective] disorders	0.000	0.996	0.004
F34.0 Cyclothymia	0.000	0.996	0.004
F41.1 Generalised anxiety disorder	0.000	0.996	0.004
G83.4 Cauda equina syndrome	0.004	0.996	0.000
F34.1 Dysthymia	0.000	0.996	0.003
F38.8 Other specified mood [affective] disorders	0.000	0.996	0.003
Z12.8 Special screening examination for neoplasm of other sites	0.004	0.996	0.000
F30.1 Mania without psychotic symptoms	0.000	0.997	0.003
F30.8 Other manic episodes	0.000	0.997	0.003
F30.2 Mania with psychotic symptoms	0.000	0.997	0.003
I20.8 Other forms of angina pectoris	0.000	0.997	0.003
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.003	0.997	0.000
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
R27.8 Other and unspecified lack of coordination	0.003	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
M89.86 Other specified disorders of bone (Lower leg)	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.997	0.000
G83.9 Paralytic syndrome, unspecified	0.003	0.997	0.000
G83 Other paralytic syndromes	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.997	0.003
G24.9 Dystonia, unspecified	0.000	0.997	0.003
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
L81.9 Disorder of pigmentation, unspecified	0.000	0.997	0.003
F30.0 Hypomania	0.000	0.997	0.002
M87.2 Osteonecrosis due to previous trauma	0.002	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
F32.9 Depressive episode, unspecified	0.000	0.998	0.002
H80-H83 Diseases of inner ear	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
G83.5 Locked-in syndrome	0.002	0.998	0.000
G83.3 Monoplegia, unspecified	0.002	0.998	0.000
G83.0 Diplegia of upper limbs	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.002
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
Z90.8 Acquired absence of other organs	0.002	0.998	0.000
M51.9 Intervertebral disk disorder, unspecified	0.000	0.998	0.002
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
K29.4 Chronic atrophic gastritis	0.002	0.998	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.002	0.998	0.000
R25.0 Abnormal head movements	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.000	0.998	0.002
M89 Other disorders of bone	0.002	0.998	0.000
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
L92.0 Granuloma annulare	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
N71.1 Chronic inflammatory disease of uterus	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
F44.4 Dissociative motor disorders	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.000	0.998	0.002
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
H80.8 Other otosclerosis	0.002	0.998	0.000
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.998	0.002
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
D26 Other benign neoplasms of uterus	0.002	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.001	0.998	0.000
M89.2 Other disorders of bone development and growth	0.001	0.998	0.000
M89.1 Epiphyseal arrest	0.001	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.002	0.998	0.000
V09.0 Pedestrian injured in nontraffic accident involving other and unspecified motor vehicles	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
N95 Menopausal and other perimenopausal disorders	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.001	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
F45.3 Somatoform autonomic dysfunction	0.000	0.998	0.002
C18.9 Colon, unspecified	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.998	0.002
R32 Unspecified urinary incontinence	0.000	0.998	0.002
L50.9 Urticaria, unspecified	0.000	0.998	0.002
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.001	0.998	0.000
M89.3 Hypertrophy of bone	0.001	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
I31 Other diseases of pericardium	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
C67.0 Trigone of bladder	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.998	0.000
D26.7 Other parts of uterus	0.001	0.998	0.000
F44.5 Dissociative convulsions	0.000	0.998	0.001
F45.1 Undifferentiated somatoform disorder	0.000	0.998	0.001
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.001	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
T87.4 Infection of amputation stump	0.000	0.998	0.001
F44 Dissociative [conversion] disorders	0.000	0.998	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.999	0.001
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.999	0.001
D47.2 Monoclonal gammopathy	0.001	0.999	0.000
I31.0 Chronic adhesive pericarditis	0.000	0.999	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.999	0.001
F41.8 Other specified anxiety disorders	0.000	0.999	0.001
M89.5 Osteolysis	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.999	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.999	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.999	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.001	0.999	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.001	0.999	0.000
M89.14 Epiphyseal arrest (Hand)	0.001	0.999	0.000
M89.13 Epiphyseal arrest (Forearm)	0.001	0.999	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.001	0.999	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.001	0.999	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.001	0.999	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.001	0.999	0.000
M89.28 Other disorders of bone development and growth (Other)	0.001	0.999	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.001	0.999	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.001	0.999	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.001	0.999	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.001	0.999	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.001	0.999	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.001	0.999	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.001	0.999	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.001	0.999	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.001	0.999	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.001	0.999	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.001	0.999	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.001	0.999	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.001	0.999	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.001	0.999	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.001	0.999	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.001	0.999	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.001	0.999	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.001	0.999	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.001	0.999	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.001	0.999	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.001	0.999	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.001	0.999	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.001	0.999	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.001	0.999	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.001	0.999	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.001	0.999	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
C22.7 Other specified carcinomas of liver	0.001	0.999	0.000
C22.4 Other sarcomas of liver	0.001	0.999	0.000
C22.3 Angiosarcoma of liver	0.001	0.999	0.000
C22.2 Hepatoblastoma	0.001	0.999	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.000	0.999	0.001
M89.38 Hypertrophy of bone (Other)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.999	0.001
O12.0 Gestational oedema	0.001	0.999	0.000
M87 Osteonecrosis	0.001	0.999	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.999	0.001
H91.8 Other specified hearing loss	0.001	0.999	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.001	0.999	0.000
R25.3 Fasciculation	0.001	0.999	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.001	0.999	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.001	0.999	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.001	0.999	0.000
M89.34 Hypertrophy of bone (Hand)	0.001	0.999	0.000
M89.33 Hypertrophy of bone (Forearm)	0.001	0.999	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.001	0.999	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.001	0.999	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.001	0.999	0.000
V09.2 Pedestrian injured in traffic accident involving other and unspecified motor vehicles	0.001	0.999	0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.001	0.999	0.000
F45.4 Persistent somatoform pain disorder	0.000	0.999	0.001
G82.5 Tetraplegia, unspecified	0.000	0.999	0.001
I31.8 Other specified diseases of pericardium	0.000	0.999	0.001
I31.2 Haemopericardium, not elsewhere classified	0.000	0.999	0.001
I31.1 Chronic constrictive pericarditis	0.000	0.999	0.001
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.001	0.999	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.001	0.999	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.001	0.999	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.000	0.999	0.001
T87.6 Other and unspecified complications of amputation stump	0.000	0.999	0.001
T92.9 Sequelae of unspecified injury of upper limb	0.001	0.999	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.000	0.999	0.001
G24 Dystonia	0.000	0.999	0.001
V49 Car occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
G24.8 Other dystonia	0.000	0.999	0.001
N95.1 Menopausal and female climacteric states	0.001	0.999	0.000
V09.9 Pedestrian injured in unspecified transport accident	0.001	0.999	0.000
V09.3 Pedestrian injured in unspecified traffic accident	0.001	0.999	0.000
C22.0 Liver cell carcinoma	0.001	0.999	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.999	0.001
F44.8 Other dissociative [conversion] disorders	0.000	0.999	0.001
F44.7 Mixed dissociative [conversion] disorders	0.000	0.999	0.001
F44.6 Dissociative anaesthesia and sensory loss	0.000	0.999	0.001
F44.3 Trance and possession disorders	0.000	0.999	0.001
F44.2 Dissociative stupor	0.000	0.999	0.001
F44.1 Dissociative fugue	0.000	0.999	0.001
F45.9 Somatoform disorder, unspecified	0.000	0.999	0.001
Z90.6 Acquired absence of other parts of urinary tract	0.001	0.999	0.000
V09 Pedestrian injured in other and unspecified transport accidents	0.001	0.999	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.999	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.999	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
M89.59 Osteolysis (Site unspecified)	0.001	0.999	0.000
M89.58 Osteolysis (Other)	0.001	0.999	0.000
M89.57 Osteolysis (Ankle and foot)	0.001	0.999	0.000
M89.56 Osteolysis (Lower leg)	0.001	0.999	0.000
M89.54 Osteolysis (Hand)	0.001	0.999	0.000
M89.53 Osteolysis (Forearm)	0.001	0.999	0.000
M89.52 Osteolysis (Upper arm)	0.001	0.999	0.000
M89.51 Osteolysis (Shoulder region)	0.001	0.999	0.000
M89.50 Osteolysis (Multiple sites)	0.001	0.999	0.000
S20.3 Other superficial injuries of front wall of thorax	0.001	0.999	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.001	0.999	0.000
H91 Other hearing loss	0.001	0.999	0.000
F44.0 Dissociative amnesia	0.000	0.999	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.001	0.999	0.000
M31.3 Wegener's granulomatosis	0.001	0.999	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.999	0.000
Q27.4 Congenital phlebectasia	0.000	0.999	0.001
Q27.2 Other congenital malformations of renal artery	0.000	0.999	0.001
Q27.1 Congenital renal artery stenosis	0.000	0.999	0.001
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.999	0.001
Z96.7 Presence of other bone and tendon implants	0.001	0.999	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
D26.1 Corpus uteri	0.001	0.999	0.000
M89.04 Algoneurodystrophy (Hand)	0.001	0.999	0.000
F45.0 Somatisation disorder	0.000	0.999	0.001
M87.3 Other secondary osteonecrosis	0.001	0.999	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S65.1 Injury of radial artery at wrist and hand level	0.000	0.999	0.001
F41 Other anxiety disorders	0.000	0.999	0.001
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.999	0.001
M89.03 Algoneurodystrophy (Forearm)	0.001	0.999	0.000
G24.1 Idiopathic familial dystonia	0.000	0.999	0.001
V49.8 Car occupant [any] injured in other specified transport accidents	0.001	0.999	0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.001	0.999	0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.001	0.999	0.000
Z50 Care involving use of rehabilitation procedures	0.001	0.999	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.001	0.999	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.999	0.001
G24.5 Blepharospasm	0.000	0.999	0.001
G24.4 Idiopathic orofacial dystonia	0.000	0.999	0.001
G24.2 Idiopathic nonfamilial dystonia	0.000	0.999	0.001
G82.2 Paraplegia, unspecified	0.000	0.999	0.001
H33.5 Other retinal detachments	0.000	0.999	0.001
K00.6 Disturbances in tooth eruption	0.001	0.999	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.999	0.001
K70.3 Alcoholic cirrhosis of liver	0.001	0.999	0.000
M87.1 Osteonecrosis due to drugs	0.001	0.999	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.001	0.999	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.999	0.001
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.999	0.001
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.999	0.001
F42.0 Predominantly obsessional thoughts or ruminations	0.000	0.999	0.001
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
G82.1 Spastic paraplegia	0.000	0.999	0.001
H66.3 Other chronic suppurative otitis media	0.001	0.999	0.000
H91.0 Ototoxic hearing loss	0.001	0.999	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.999	0.001
R07.0 Pain in throat	0.001	0.999	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.001	0.999	0.000
F42 Obsessive-compulsive disorder	0.000	0.999	0.001
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.999	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.999	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.001	0.999	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.001	0.999	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.999	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.001	0.999	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.001	0.999	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.001	0.999	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.001	0.999	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.001	0.999	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.999	0.001
H83.8 Other specified diseases of inner ear	0.001	0.999	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.999	0.001
R27.0 Ataxia, unspecified	0.001	0.999	0.001
T78.2 Anaphylactic shock, unspecified	0.001	0.999	0.000
M86-M90 Other osteopathies	0.001	0.999	0.000
G24.3 Spasmodic torticollis	0.000	0.999	0.001
G80.2 Infantile hemiplegia	0.001	0.999	0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
F31 Bipolar affective disorder	0.000	0.999	0.001
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.001	0.999	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.38 Other secondary osteonecrosis (Other)	0.001	0.999	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations