TreeWAS – Variant ID: rs12604324

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y42.7 Androgens and anabolic congeners	0.132	0.868	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.116	0.884	0.000
Y42.5 Other oestrogens and progestogens	0.109	0.891	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.103	0.897	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.096	0.904	0.000
Y42.9 Other and unspecified hormone antagonists	0.084	0.916	0.000
Y42.4 Oral contraceptives	0.084	0.916	0.000
Y42.2 Antithyroid drugs	0.084	0.916	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.083	0.917	0.000
Y42.1 Thyroid hormones and substitutes	0.080	0.920	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.070	0.930	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.028	0.972	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.980	0.020
D05.1 Intraductal carcinoma in situ	0.016	0.984	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.013	0.987	0.000
D05 Carcinoma in situ of breast	0.013	0.987	0.000
D05.7 Other carcinoma in situ of breast	0.010	0.990	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.990	0.010
D05.0 Lobular carcinoma in situ	0.008	0.992	0.000
L53.9 Erythematous condition, unspecified	0.000	0.993	0.007
K80.2 Calculus of gallbladder without cholecystitis	0.007	0.993	0.000
H43.1 Vitreous haemorrhage	0.007	0.993	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.994	0.006
N41.1 Chronic prostatitis	0.000	0.994	0.006
M81.98 Osteoporosis, unspecified (Other)	0.005	0.995	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.005	0.995	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.995	0.005
I27.9 Pulmonary heart disease, unspecified	0.000	0.995	0.005
I27 Other pulmonary heart diseases	0.000	0.995	0.005
M81.9 Osteoporosis, unspecified	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.996	0.004
N41.0 Acute prostatitis	0.000	0.996	0.004
M81.90 Osteoporosis, unspecified (Multiple sites)	0.004	0.996	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.996	0.004
R73.0 Abnormal glucose tolerance test	0.004	0.996	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.996	0.004
M81.96 Osteoporosis, unspecified (Lower leg)	0.004	0.996	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.004	0.996	0.000
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
F60.9 Personality disorder, unspecified	0.000	0.996	0.004
E04 Other non-toxic goitre	0.000	0.996	0.004
I27.0 Primary pulmonary hypertension	0.000	0.996	0.004
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
N41 Inflammatory diseases of prostate	0.000	0.996	0.004
M77.9 Enthesopathy, unspecified	0.003	0.996	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
K50.8 Other Crohn's disease	0.003	0.997	0.000
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.003	0.997	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.003	0.997	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.003	0.997	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.003	0.997	0.000
F60 Specific personality disorders	0.000	0.997	0.003
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.003	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
K51.2 Ulcerative (chronic) proctitis	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
D00-D09 In situ neoplasms	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
E04.8 Other specified non-toxic goitre	0.000	0.997	0.003
M77.96 Enthesopathy, unspecified (Lower leg)	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.997	0.003
N41.3 Prostatocystitis	0.000	0.997	0.003
N41.2 Abscess of prostate	0.000	0.997	0.003
M77.99 Enthesopathy, unspecified (Site unspecified)	0.003	0.997	0.000
M77.98 Enthesopathy, unspecified (Other)	0.003	0.997	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.003	0.997	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.003	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
H43 Disorders of vitreous body	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.997	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.000	0.997	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
L27 Dermatitis due to substances taken internally	0.000	0.997	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.997	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.997	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.997	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.997	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.997	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.997	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.997	0.003
F60.8 Other specific personality disorders	0.000	0.997	0.002
F60.5 Anankastic personality disorder	0.000	0.997	0.002
F60.4 Histrionic personality disorder	0.000	0.997	0.002
F60.2 Dissocial personality disorder	0.000	0.997	0.002
F60.1 Schizoid personality disorder	0.000	0.997	0.002
F60.0 Paranoid personality disorder	0.000	0.997	0.002
M80 Osteoporosis with pathological fracture	0.002	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.997	0.002
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
D07.2 Vagina	0.002	0.997	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
D00.1 Oesophagus	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
L53 Other erythematous conditions	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.88 Other osteoporosis (Other)	0.002	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
D07.0 Endometrium	0.002	0.998	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.000	0.998	0.002
N72 Inflammatory disease of cervix uteri	0.000	0.998	0.002
D09.0 Bladder	0.002	0.998	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.998	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.000	0.998	0.002
K75.0 Abscess of liver	0.000	0.998	0.002
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
D00.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
H43.0 Vitreous prolapse	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
D00.2 Stomach	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
I25.2 Old myocardial infarction	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.998	0.002
L27.8 Dermatitis due to other substances taken internally	0.000	0.998	0.002
L27.2 Dermatitis due to ingested food	0.000	0.998	0.002
D02 Carcinoma in situ of middle ear and respiratory system	0.002	0.998	0.000
I25 Chronic ischaemic heart disease	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
D07.6 Other and unspecified male genital organs	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
D07.4 Penis	0.002	0.998	0.000
D07.1 Vulva	0.002	0.998	0.000
N90.6 Hypertrophy of vulva	0.002	0.998	0.000
D10.1 Tongue	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
L53.3 Other chronic figurate erythema	0.000	0.998	0.002
L53.2 Erythema marginatum	0.000	0.998	0.002
L53.1 Erythema annulare centrifugum	0.000	0.998	0.002
M83 Adult osteomalacia	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
I25.4 Coronary artery aneurysm	0.002	0.998	0.000
D01.9 Digestive organ, unspecified	0.002	0.998	0.000
D01.7 Other specified digestive organs	0.002	0.998	0.000
D01.5 Liver, gallbladder and bile ducts	0.002	0.998	0.000
D01.4 Other and unspecified parts of intestine	0.002	0.998	0.000
D01.2 Rectum	0.002	0.998	0.000
D01.1 Rectosigmoid junction	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
D01.3 Anus and anal canal	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.000	0.998	0.002
L91.8 Other hypertrophic disorders of skin	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.002
D03 Melanoma in situ	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.998	0.002
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.002	0.998	0.000
D01.0 Colon	0.002	0.998	0.000
L53.0 Toxic erythema	0.001	0.998	0.001
R44.1 Visual hallucinations	0.000	0.998	0.002
W44.0 Home	0.000	0.998	0.002
I28 Other diseases of pulmonary vessels	0.000	0.998	0.002
K51 Ulcerative colitis	0.002	0.998	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.998	0.002
D06 Carcinoma in situ of cervix uteri	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.29 Hyperostosis of skull-Site unspec	0.002	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.002	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.002	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.002	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.002	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.002	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.002	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.002	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.002	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.002	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.002	0.998	0.000
D02.4 Respiratory system, unspecified	0.002	0.998	0.000
D02.3 Other parts of respiratory system	0.002	0.998	0.000
D02.2 Bronchus and lung	0.002	0.998	0.000
D02.1 Trachea	0.002	0.998	0.000
I25.6 Silent myocardial ischaemia	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.002	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.002	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.002	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.001	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
L72.0 Epidermal cyst	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.001	0.998	0.000
M83.8 Other adult osteomalacia	0.001	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.998	0.000
M83.4 Aluminum bone disease	0.001	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.998	0.000
M83.1 Senile osteomalacia	0.001	0.998	0.000
M83.0 Puerperal osteomalacia	0.001	0.998	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.002	0.998	0.000
L53.8 Other specified erythematous conditions	0.001	0.998	0.001
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
C53.0 Endocervix	0.000	0.998	0.002
D03.9 Melanoma in situ, unspecified	0.001	0.998	0.000
D03.8 Melanoma in situ of other sites	0.001	0.998	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.001	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.001	0.998	0.000
D03.0 Melanoma in situ of lip	0.001	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.001	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.998	0.001
I28.1 Aneurysm of pulmonary artery	0.000	0.998	0.001
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.998	0.001
K51.1 Ulcerative (chronic) ileocolitis	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
K80 Cholelithiasis	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
M85.69 Other cyst of bone (Site unspecified)	0.001	0.998	0.000
M85.68 Other cyst of bone (Other)	0.001	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.001	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.001	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.001	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.001	0.998	0.000
D06.7 Other parts of cervix	0.001	0.998	0.000
D06.1 Exocervix	0.001	0.998	0.000
D06.0 Endocervix	0.001	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.998	0.000
C53 Malignant neoplasm of cervix uteri	0.000	0.998	0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.001	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.998	0.000
D02.0 Larynx	0.001	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.001	0.998	0.000
S72.4 Fracture of lower end of femur	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations