TreeWAS – Variant ID: rs12606301

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.400	0.600
T39.1 4-Aminophenol derivatives	0.000	0.401	0.599
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.402	0.598
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.413	0.587
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.419	0.581
T40.2 Other opioids	0.000	0.427	0.573
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.462	0.538
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.463	0.537
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.472	0.528
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.478	0.522
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.483	0.517
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.501	0.499
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.521	0.479
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.532	0.468
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.547	0.453
T39.0 Salicylates	0.000	0.549	0.451
T46.1 Calcium-channel blockers	0.000	0.563	0.437
T39.4 Antirheumatics, not elsewhere classified	0.000	0.569	0.430
T39.2 Pyrazolone derivatives	0.000	0.569	0.430
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.571	0.429
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.571	0.429
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.571	0.429
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.571	0.429
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.572	0.428
T43.9 Psychotropic drug, unspecified	0.000	0.579	0.421
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.579	0.421
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.579	0.421
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.579	0.421
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.580	0.420
T43.6 Psychostimulants with abuse potential	0.000	0.582	0.417
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.583	0.416
T40.8 Lysergide [LSD]	0.000	0.583	0.416
T40.7 Cannabis (derivatives)	0.000	0.583	0.416
T40.5 Cocaine	0.000	0.583	0.416
T40.3 Methadone	0.000	0.583	0.416
T40.1 Heroin	0.000	0.583	0.416
T40.0 Opium	0.000	0.583	0.416
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.585	0.415
T40.4 Other synthetic narcotics	0.000	0.602	0.398
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.607	0.393
T36 Poisoning by systemic antibiotics	0.000	0.608	0.392
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.614	0.386
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.614	0.386
T46.7 Peripheral vasodilators	0.000	0.614	0.386
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.614	0.386
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.614	0.386
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.614	0.386
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.614	0.386
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.620	0.380
T40.6 Other and unspecified narcotics	0.000	0.623	0.377
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.625	0.375
T43.2 Other and unspecified antidepressants	0.000	0.631	0.369
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.642	0.358
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.642	0.358
T47.7 Emetics	0.000	0.642	0.358
T47.6 Antidiarrhoeal drugs	0.000	0.642	0.358
T47.5 Digestants	0.000	0.642	0.358
T47.4 Other laxatives	0.000	0.642	0.358
T47.3 Saline and osmotic laxatives	0.000	0.642	0.358
T47.2 Stimulant laxatives	0.000	0.642	0.358
T47.0 Histamine H(2)-receptor antagonists	0.000	0.642	0.358
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.656	0.344
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.656	0.343
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.656	0.343
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.656	0.343
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.656	0.343
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.656	0.343
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.656	0.343
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.656	0.343
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.656	0.343
T44.0 Anticholinesterase agents	0.000	0.656	0.343
T42.4 Benzodiazepines	0.000	0.684	0.316
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.686	0.314
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.692	0.308
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.692	0.308
T37.5 Antiviral drugs	0.000	0.692	0.308
T37.4 Anthelminthics	0.000	0.692	0.308
T37.3 Other antiprotozoal drugs	0.000	0.692	0.308
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.692	0.308
T37.1 Antimycobacterial drugs	0.000	0.692	0.308
T37.0 Sulphonamides	0.000	0.692	0.308
T41.5 Therapeutic gases	0.000	0.692	0.308
T41.4 Anaesthetic, unspecified	0.000	0.692	0.308
T41.3 Local anaesthetics	0.000	0.692	0.308
T41.2 Other and unspecified general anaesthetics	0.000	0.692	0.308
T41.1 Intravenous anaesthetics	0.000	0.692	0.308
T41.0 Inhaled anaesthetics	0.000	0.692	0.308
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.692	0.308
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.692	0.308
T48.5 Anti-common-cold drugs	0.000	0.692	0.308
T48.4 Expectorants	0.000	0.692	0.308
T48.3 Antitussives	0.000	0.692	0.308
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.692	0.308
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.692	0.308
T48.0 Oxytocic drugs	0.000	0.692	0.308
T49.9 Topical agent, unspecified	0.000	0.692	0.308
T49.8 Other topical agents	0.000	0.692	0.308
T49.7 Dental drugs, topically applied	0.000	0.692	0.308
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.692	0.308
T49.5 Ophthalmological drugs and preparations	0.000	0.692	0.308
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.692	0.308
T49.3 Emollients, demulcents and protectants	0.000	0.692	0.308
T49.2 Local astringents and local detergents	0.000	0.692	0.308
T49.1 Antipruritics	0.000	0.692	0.308
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.692	0.308
T38.9 Other and unspecified hormone antagonists	0.000	0.702	0.298
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.702	0.298
T38.7 Androgens and anabolic congeners	0.000	0.702	0.298
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.702	0.298
T38.5 Other oestrogens and progestogens	0.000	0.702	0.298
T38.4 Oral contraceptives	0.000	0.702	0.298
T38.2 Antithyroid drugs	0.000	0.702	0.298
T38.0 Glucocorticoids and synthetic analogues	0.000	0.702	0.298
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.706	0.293
T36.9 Systemic antibiotic, unspecified	0.000	0.719	0.281
T36.8 Other systemic antibiotics	0.000	0.719	0.281
T36.7 Antifungal antibiotics, systemically used	0.000	0.719	0.281
T36.6 Rifamycins	0.000	0.719	0.281
T36.5 Aminoglycosides	0.000	0.719	0.281
T36.4 Tetracyclines	0.000	0.719	0.281
T36.3 Macrolides	0.000	0.719	0.281
T36.2 Chloramphenicol group	0.000	0.719	0.281
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.719	0.281
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.727	0.273
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.727	0.273
T42.3 Barbiturates	0.000	0.727	0.273
T42.2 Succinimides and oxazolidinediones	0.000	0.727	0.273
T42.1 Iminostilbenes	0.000	0.727	0.273
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.733	0.267
T38.1 Thyroid hormones and substitutes	0.000	0.738	0.262
T42.0 Hydantoin derivatives	0.000	0.745	0.254
T50.7 Analeptics and opioid receptor antagonists	0.000	0.753	0.247
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.753	0.247
T50.5 Appetite depressants	0.000	0.753	0.247
T50.4 Drugs affecting uric acid metabolism	0.000	0.753	0.247
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.753	0.247
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.753	0.247
T50.1 Loop [high-ceiling] diuretics	0.000	0.753	0.247
T50.0 Mineralocorticoids and their antagonists	0.000	0.753	0.247
T36.0 Penicillins	0.000	0.756	0.244
T50.8 Diagnostic agents	0.000	0.787	0.213
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.789	0.210
T45.8 Other primarily systemic and haematological agents	0.000	0.789	0.210
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.789	0.210
T45.6 Fibrinolysis-affecting drugs	0.000	0.789	0.210
T45.4 Iron and its compounds	0.000	0.789	0.210
T45.3 Enzymes, not elsewhere classified	0.000	0.789	0.210
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.792	0.208
T45.0 Antiallergic and antiemetic drugs	0.000	0.795	0.205
T45.2 Vitamins, not elsewhere classified	0.000	0.806	0.194
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.816	0.183
N32 Other disorders of bladder	0.000	0.821	0.179
N32.9 Bladder disorder, unspecified	0.000	0.823	0.177
N30-N39 Other diseases of urinary system	0.000	0.824	0.176
N30 Cystitis	0.000	0.827	0.173
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.829	0.171
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.829	0.171
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.830	0.169
N32.0 Bladder-neck obstruction	0.000	0.833	0.167
T45.5 Anticoagulants	0.001	0.835	0.165
N30.8 Other cystitis	0.000	0.841	0.159
N30.2 Other chronic cystitis	0.000	0.842	0.158
N32.1 Vesicointestinal fistula	0.000	0.845	0.155
N35 Urethral stricture	0.000	0.845	0.155
N30.1 Interstitial cystitis (chronic)	0.000	0.855	0.145
N35.9 Urethral stricture, unspecified	0.000	0.855	0.145
N30.0 Acute cystitis	0.000	0.855	0.145
N34 Urethritis and urethral syndrome	0.000	0.863	0.137
N30.3 Trigonitis	0.000	0.863	0.137
N32.3 Diverticulum of bladder	0.000	0.869	0.131
N32.4 Rupture of bladder, nontraumatic	0.000	0.872	0.128
N32.2 Vesical fistula, not elsewhere classified	0.000	0.872	0.128
N37 Urethral disorders in diseases classified elsewhere	0.000	0.873	0.127
N33 Bladder disorders in diseases classified elsewhere	0.000	0.873	0.127
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.874	0.126
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.877	0.123
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.877	0.123
N36 Other disorders of urethra	0.000	0.880	0.120
N30.4 Irradiation cystitis	0.000	0.885	0.115
N35.1 Postinfective urethral stricture, not elsewhere classified	0.000	0.889	0.111
N35.0 Posttraumatic urethral stricture	0.000	0.889	0.111
N34.2 Other urethritis	0.000	0.892	0.108
N34.3 Urethral syndrome, unspecified	0.000	0.899	0.101
N36.8 Other specified disorders of urethra	0.000	0.901	0.099
N34.1 Nonspecific urethritis	0.000	0.901	0.099
N34.0 Urethral abscess	0.000	0.901	0.099
N36.3 Prolapsed urethral mucosa	0.000	0.905	0.095
N35.8 Other urethral stricture	0.000	0.908	0.092
N33.8 Bladder disorders in other diseases classified elsewhere	0.000	0.909	0.091
N33.0 Tuberculous cystitis	0.000	0.909	0.091
N37.8 Other urethral disorders in diseases classified elsewhere	0.000	0.909	0.091
N37.0 Urethritis in diseases classified elsewhere	0.000	0.909	0.091
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.910	0.090
N36.0 Urethral fistula	0.000	0.916	0.084
N36.1 Urethral diverticulum	0.000	0.917	0.083
N36.9 Urethral disorder, unspecified	0.000	0.917	0.083
N36.2 Urethral caruncle	0.000	0.952	0.048
N30.9 Cystitis, unspecified	0.000	0.977	0.022
D05.9 Carcinoma in situ of breast, unspecified	0.017	0.983	0.000
D05 Carcinoma in situ of breast	0.017	0.983	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.017	0.983	0.000
D03 Melanoma in situ	0.017	0.983	0.000
D00-D09 In situ neoplasms	0.016	0.984	0.000
R47.1 Dysarthria and anarthria	0.015	0.985	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.014	0.985	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.014	0.986	0.000
D05.1 Intraductal carcinoma in situ	0.014	0.986	0.000
D03.4 Melanoma in situ of scalp and neck	0.014	0.986	0.000
D04 Carcinoma in situ of skin	0.014	0.986	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.987	0.013
D05.0 Lobular carcinoma in situ	0.013	0.987	0.000
D04.5 Skin of trunk	0.013	0.987	0.000
D07.5 Prostate	0.013	0.987	0.000
D03.9 Melanoma in situ, unspecified	0.012	0.988	0.000
D03.8 Melanoma in situ of other sites	0.012	0.988	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.012	0.988	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.012	0.988	0.000
D03.0 Melanoma in situ of lip	0.012	0.988	0.000
N89.5 Stricture and atresia of vagina	0.012	0.988	0.000
D03.5 Melanoma in situ of trunk	0.012	0.988	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.012	0.988	0.000
D04.1 Skin of eyelid, including canthus	0.012	0.988	0.000
D07.2 Vagina	0.012	0.988	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.012	0.988	0.000
D05.7 Other carcinoma in situ of breast	0.011	0.988	0.000
D09 Carcinoma in situ of other and unspecified sites	0.011	0.989	0.000
D07.4 Penis	0.011	0.989	0.000
D04.7 Skin of lower limb, including hip	0.011	0.989	0.000
D07.1 Vulva	0.011	0.989	0.000
D04.3 Skin of other and unspecified parts of face	0.011	0.989	0.000
M24.2 Disorder of ligament	0.011	0.989	0.000
D07.6 Other and unspecified male genital organs	0.011	0.989	0.000
D07.3 Other and unspecified female genital organs	0.011	0.989	0.000
D07.0 Endometrium	0.011	0.989	0.000
D04.4 Skin of scalp and neck	0.010	0.990	0.000
D04.9 Skin, unspecified	0.010	0.990	0.000
D04.8 Skin of other sites	0.010	0.990	0.000
D04.0 Skin of lip	0.010	0.990	0.000
M24.23 Disorder of ligament (Forearm)	0.010	0.990	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.010	0.990	0.000
D06 Carcinoma in situ of cervix uteri	0.010	0.990	0.000
D04.2 Skin of ear and external auricular canal	0.010	0.990	0.000
M24.24 Disorder of ligament (Hand)	0.010	0.990	0.000
R47 Speech disturbances, not elsewhere classified	0.010	0.990	0.000
M24.1 Other articular cartilage disorders	0.010	0.990	0.000
M24 Other specific joint derangements	0.010	0.990	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.009	0.990	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.009	0.991	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.009	0.991	0.000
D01.9 Digestive organ, unspecified	0.009	0.991	0.000
D01.7 Other specified digestive organs	0.009	0.991	0.000
D01.5 Liver, gallbladder and bile ducts	0.009	0.991	0.000
D01.4 Other and unspecified parts of intestine	0.009	0.991	0.000
D01.3 Anus and anal canal	0.009	0.991	0.000
D01.2 Rectum	0.009	0.991	0.000
D01.1 Rectosigmoid junction	0.009	0.991	0.000
D01.0 Colon	0.009	0.991	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.009	0.991	0.000
D00.2 Stomach	0.008	0.991	0.000
D00.1 Oesophagus	0.008	0.991	0.000
D23.7 Skin of lower limb, including hip	0.000	0.991	0.009
M24.6 Ankylosis of joint	0.008	0.991	0.000
R47.0 Dysphasia and aphasia	0.008	0.992	0.000
D09.9 Carcinoma in situ, unspecified	0.008	0.992	0.000
D09.7 Carcinoma in situ of other specified sites	0.008	0.992	0.000
D09.3 Thyroid and other endocrine glands	0.008	0.992	0.000
D09.2 Eye	0.008	0.992	0.000
D09.1 Other and unspecified urinary organs	0.008	0.992	0.000
D00.0 Lip, oral cavity and pharynx	0.008	0.992	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.008	0.992	0.000
M24.5 Contracture of joint	0.008	0.992	0.000
N89 Other noninflammatory disorders of vagina	0.008	0.992	0.000
D09.0 Bladder	0.008	0.992	0.000
M24.29 Disorder of ligament (Site unspecified)	0.008	0.992	0.000
M24.28 Disorder of ligament (Other)	0.008	0.992	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.008	0.992	0.000
M24.22 Disorder of ligament (Upper arm)	0.008	0.992	0.000
M24.20 Disorder of ligament (Multiple sites)	0.008	0.992	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.008	0.992	0.000
M24.21 Disorder of ligament (Shoulder region)	0.008	0.992	0.000
M24.26 Disorder of ligament (Lower leg)	0.008	0.992	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.008	0.992	0.000
D02.4 Respiratory system, unspecified	0.007	0.992	0.000
D02.3 Other parts of respiratory system	0.007	0.992	0.000
D02.2 Bronchus and lung	0.007	0.992	0.000
D02.1 Trachea	0.007	0.992	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.007	0.993	0.000
D06.7 Other parts of cervix	0.007	0.993	0.000
D06.1 Exocervix	0.007	0.993	0.000
D06.0 Endocervix	0.007	0.993	0.000
M24.7 Protrusio acetabuli	0.007	0.993	0.000
R20.2 Paraesthesia of skin	0.000	0.993	0.007
M24.19 Other articular cartilage disorders (Site unspecified)	0.007	0.993	0.000
M24.18 Other articular cartilage disorders (Other)	0.007	0.993	0.000
M24.14 Other articular cartilage disorders (Hand)	0.007	0.993	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.007	0.993	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.007	0.993	0.000
M24.9 Joint derangement, unspecified	0.007	0.993	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.007	0.993	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.007	0.993	0.000
D04.6 Skin of upper limb, including shoulder	0.007	0.993	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.007	0.993	0.000
M24.56 Contracture of joint (Lower leg)	0.007	0.993	0.000
R47.8 Other and unspecified speech disturbances	0.007	0.993	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.006	0.993	0.000
M24.51 Contracture of joint (Shoulder region)	0.006	0.994	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.006	0.994	0.000
M24.68 Ankylosis of joint (Other)	0.006	0.994	0.000
M24.66 Ankylosis of joint (Lower leg)	0.006	0.994	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.006	0.994	0.000
M24.64 Ankylosis of joint (Hand)	0.006	0.994	0.000
M24.63 Ankylosis of joint (Forearm)	0.006	0.994	0.000
M24.62 Ankylosis of joint (Upper arm)	0.006	0.994	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.006	0.994	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.006	0.994	0.000
M24.0 Loose body in joint	0.006	0.994	0.000
M24.54 Contracture of joint (Hand)	0.006	0.994	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.006	0.994	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.006	0.994	0.000
H90.3 Sensorineural hearing loss, bilateral	0.006	0.994	0.000
M24.59 Contracture of joint (Site unspecified)	0.006	0.994	0.000
M24.58 Contracture of joint (Other)	0.006	0.994	0.000
M24.57 Contracture of joint (Ankle and foot)	0.006	0.994	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.006	0.994	0.000
M24.53 Contracture of joint (Forearm)	0.006	0.994	0.000
M24.52 Contracture of joint (Upper arm)	0.006	0.994	0.000
M24.50 Contracture of joint (Multiple sites)	0.006	0.994	0.000
N89.7 Haematocolpos	0.006	0.994	0.000
N89.4 Leukoplakia of vagina	0.006	0.994	0.000
N89.3 Dysplasia of vagina, unspecified	0.006	0.994	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.006	0.994	0.000
N89.1 Moderate vaginal dysplasia	0.006	0.994	0.000
N89.0 Mild vaginal dysplasia	0.006	0.994	0.000
S42.30 Fracture of shaft of humerus (closed)	0.006	0.994	0.000
D02.0 Larynx	0.006	0.994	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.006	0.994	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.006	0.994	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.006	0.994	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.006	0.994	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.006	0.994	0.000
M24.79 Protrusio acetabuli-Site unspec	0.005	0.994	0.000
M24.78 Protrusio acetabuli-Other	0.005	0.994	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.005	0.994	0.000
M24.76 Protrusio acetabuli-Lower leg	0.005	0.994	0.000
M24.74 Protrusio acetabuli-Hand	0.005	0.994	0.000
M24.73 Protrusio acetabuli-Forearm	0.005	0.994	0.000
M24.72 Protrusio acetabuli-Upper arm	0.005	0.994	0.000
M24.71 Protrusio acetabuli-Shldr region	0.005	0.994	0.000
M24.70 Protrusio acetabuli-Mult sites	0.005	0.994	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
D06.9 Cervix, unspecified	0.005	0.995	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.005	0.995	0.000
M24.98 Joint derangement, unspecified (Other)	0.005	0.995	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.005	0.995	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.005	0.995	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M24.94 Joint derangement, unspecified (Hand)	0.005	0.995	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.005	0.995	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.005	0.995	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.005	0.995	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.005	0.995	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.005	0.995	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.005	0.995	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.005	0.995	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
M24.03 Loose body in joint (Forearm)	0.005	0.995	0.000
M24.07 Loose body in joint (Ankle and foot)	0.005	0.995	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.005	0.995	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.005	0.995	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.005	0.995	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.005	0.995	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.005	0.995	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.005	0.995	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.005	0.995	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.005	0.995	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M24.09 Loose body in joint (Site unspecified)	0.005	0.995	0.000
M24.08 Loose body in joint (Other)	0.005	0.995	0.000
M24.06 Loose body in joint-Lower leg	0.005	0.995	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.005	0.995	0.000
M24.04 Loose body in joint (Hand)	0.005	0.995	0.000
M24.00 Loose body in joint (Multiple sites)	0.005	0.995	0.000
N89.6 Tight hymenal ring	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.995	0.005
N80.1 Endometriosis of ovary	0.000	0.996	0.004
M24.01 Loose body in joint (Shoulder region)	0.004	0.996	0.000
M13.9 Arthritis, unspecified	0.004	0.996	0.000
M13.93 Arthritis, unspecified (Forearm)	0.004	0.996	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.004	0.996	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.996	0.004
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
H90.2 Conductive hearing loss, unspecified	0.004	0.996	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.996	0.004
C78.7 Secondary malignant neoplasm of liver	0.000	0.996	0.004
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.996	0.004
R47-R49 Symptoms and signs involving speech and voice	0.004	0.996	0.000
S42.3 Fracture of shaft of humerus	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.996	0.004
H20 Iridocyclitis	0.003	0.996	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.997	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.997	0.003
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H90.0 Conductive hearing loss, bilateral	0.003	0.997	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.003	0.997	0.000
R80 Isolated proteinuria	0.003	0.997	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.997	0.003
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.003	0.997	0.000
H16.0 Corneal ulcer	0.003	0.997	0.000
H20.8 Other iridocyclitis	0.003	0.997	0.000
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
H17.8 Other corneal scars and opacities	0.003	0.997	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.997	0.003
H17.9 Corneal scar and opacity, unspecified	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.997	0.003
C77.9 Lymph node, unspecified	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.003	0.997	0.000
T17.2 Foreign body in pharynx	0.003	0.997	0.000
S42.31 Fracture of shaft of humerus (open)	0.003	0.997	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.997	0.003
H17.1 Other central corneal opacity	0.003	0.997	0.000
H17.0 Adherent leukoma	0.003	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.997	0.003
H16.8 Other keratitis	0.003	0.997	0.000
H16.4 Corneal neovascularisation	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
H43.1 Vitreous haemorrhage	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
H15 Disorders of sclera	0.003	0.997	0.000
N39 Other disorders of urinary system	0.000	0.997	0.003
H21.0 Hyphaema	0.003	0.997	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.997	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.997	0.003
J86.9 Pyothorax without fistula	0.003	0.997	0.000
R87.6 Abnormal cytological findings	0.003	0.997	0.000
I08 Multiple valve diseases	0.003	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.997	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.997	0.000
H21.4 Pupillary membranes	0.002	0.997	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.997	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.997	0.000
Z86.0 Personal history of other neoplasms	0.003	0.997	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.997	0.003
H21.8 Other specified disorders of iris and ciliary body	0.002	0.997	0.000
R49 Voice disturbances	0.003	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.997	0.000
H16.9 Keratitis, unspecified	0.002	0.998	0.000
H44.2 Degenerative myopia	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
Z88.5 Personal history of allergy to narcotic agent	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
R48.8 Other and unspecified symbolic dysfunctions	0.002	0.998	0.000
R48.2 Apraxia	0.002	0.998	0.000
R48.1 Agnosia	0.002	0.998	0.000
R48.0 Dyslexia and alexia	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations