TreeWAS – Variant ID: rs1262476

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.782	0.218	0.000
I10-I15 Hypertensive diseases	0.345	0.655	0.000
I11 Hypertensive heart disease	0.265	0.735	0.000
I13 Hypertensive heart and renal disease	0.243	0.756	0.000
I12 Hypertensive renal disease	0.238	0.762	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.202	0.798	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.195	0.804	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.185	0.815	0.000
I15 Secondary hypertension	0.178	0.822	0.000
I12.0 Hypertensive renal disease with renal failure	0.177	0.823	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.175	0.825	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.171	0.829	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.163	0.836	0.000
I12.9 Hypertensive renal disease without renal failure	0.155	0.845	0.000
I72 Other aneurysm	0.150	0.850	0.000
I60-I69 Cerebrovascular diseases	0.149	0.851	0.000
Chapter IX Diseases of the circulatory system	0.148	0.852	0.000
I67 Other cerebrovascular diseases	0.147	0.853	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.146	0.854	0.000
I72.4 Aneurysm of artery of lower extremity	0.144	0.856	0.000
I60 Subarachnoid haemorrhage	0.139	0.861	0.000
N28.1 Cyst of kidney, acquired	0.136	0.864	0.000
I71 Aortic aneurysm and dissection	0.136	0.864	0.000
I67.1 Cerebral aneurysm, nonruptured	0.133	0.867	0.000
I15.2 Hypertension secondary to endocrine disorders	0.133	0.867	0.000
I67.8 Other specified cerebrovascular diseases	0.133	0.867	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.132	0.868	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.132	0.868	0.000
I72.0 Aneurysm of carotid artery	0.132	0.868	0.000
I67.9 Cerebrovascular disease, unspecified	0.128	0.872	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.127	0.873	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.123	0.877	0.000
I63 Cerebral infarction	0.123	0.877	0.000
I71.0 Dissection of aorta [any part]	0.122	0.877	0.000
I15.8 Other secondary hypertension	0.122	0.878	0.000
I15.0 Renovascular hypertension	0.122	0.878	0.000
I60.8 Other subarachnoid haemorrhage	0.121	0.879	0.000
I72.8 Aneurysm of other specified arteries	0.120	0.880	0.000
I05-I09 Chronic rheumatic heart diseases	0.120	0.880	0.000
I15.9 Seconday hypertension, unspecified	0.119	0.881	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.118	0.882	0.000
I61 Intracerebral haemorrhage	0.117	0.883	0.000
I72.9 Aneurysm of unspecified site	0.116	0.883	0.000
I00-I02 Acute rheumatic fever	0.116	0.884	0.000
I72.2 Aneurysm of renal artery	0.115	0.885	0.000
I72.3 Aneurysm of iliac artery	0.112	0.888	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.112	0.888	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.112	0.888	0.000
I72.1 Aneurysm of artery of upper extremity	0.111	0.889	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.110	0.890	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.109	0.891	0.000
I63.8 Other cerebral infarction	0.109	0.891	0.000
I08 Multiple valve diseases	0.108	0.892	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.108	0.892	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.108	0.892	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.107	0.893	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.105	0.895	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.105	0.895	0.000
I67.5 Moyamoya disease	0.105	0.895	0.000
I67.3 Progressive vascular leukoencephalopathy	0.105	0.895	0.000
I67.4 Hypertensive encephalopathy	0.105	0.895	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.105	0.895	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.103	0.896	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.102	0.898	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.101	0.899	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.100	0.900	0.000
I08.0 Disorders of both mitral and aortic valves	0.099	0.901	0.000
I78 Diseases of capillaries	0.099	0.901	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.099	0.901	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.098	0.901	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.098	0.902	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.098	0.902	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.097	0.903	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.096	0.904	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.096	0.904	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.095	0.905	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.095	0.905	0.000
I70 Atherosclerosis	0.094	0.906	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.094	0.906	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.093	0.907	0.000
I61.8 Other intracerebral haemorrhage	0.092	0.908	0.000
I00 Rheumatic fever without mention of heart involvement	0.092	0.908	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.091	0.909	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.091	0.909	0.000
I07 Rheumatic tricuspid valve diseases	0.091	0.909	0.000
I79.1 Aortitis in diseases classified elsewhere	0.089	0.911	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.089	0.911	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.088	0.911	0.000
I67.2 Cerebral atherosclerosis	0.088	0.912	0.000
I15.1 Hypertension secondary to other renal disorders	0.088	0.912	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.088	0.912	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.087	0.913	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.085	0.915	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.084	0.915	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.084	0.916	0.000
I09 Other rheumatic heart diseases	0.084	0.916	0.000
I02 Rheumatic chorea	0.083	0.917	0.000
I01 Rheumatic fever with heart involvement	0.083	0.917	0.000
I65.1 Occlusion and stenosis of basilar artery	0.083	0.917	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.082	0.918	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.080	0.920	0.000
I08.8 Other multiple valve diseases	0.078	0.921	0.000
I70.0 Atherosclerosis of aorta	0.078	0.922	0.000
I06 Rheumatic aortic valve diseases	0.078	0.922	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.077	0.922	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.077	0.923	0.000
I78.8 Other diseases of capillaries	0.077	0.923	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.077	0.923	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.076	0.924	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.072	0.928	0.000
I78.9 Disease of capillaries, unspecified	0.071	0.929	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.071	0.929	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.071	0.929	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.071	0.929	0.000
I74 Arterial embolism and thrombosis	0.071	0.929	0.000
I07.1 Tricuspid insufficiency	0.070	0.930	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.070	0.930	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.069	0.931	0.000
I05 Rheumatic mitral valve diseases	0.067	0.932	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.067	0.933	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.067	0.933	0.000
I70.1 Atherosclerosis of renal artery	0.066	0.934	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.066	0.934	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.065	0.934	0.000
I07.9 Tricuspid valve disease, unspecified	0.065	0.935	0.000
I07.8 Other tricuspid valve diseases	0.065	0.935	0.000
I07.2 Tricuspid stenosis with insufficiency	0.065	0.935	0.000
I07.0 Tricuspid stenosis	0.065	0.935	0.000
I70.8 Atherosclerosis of other arteries	0.063	0.937	0.000
I68.0 Cerebral amyloid angiopathy	0.062	0.937	0.000
I08.9 Multiple valve disease, unspecified	0.062	0.938	0.000
I70.9 Generalised and unspecified atherosclerosis	0.062	0.938	0.000
I62 Other nontraumatic intracranial haemorrhage	0.061	0.939	0.000
N28.0 Ischaemia and infarction of kidney	0.061	0.939	0.000
I09.8 Other specified rheumatic heart diseases	0.060	0.940	0.000
I09.2 Chronic rheumatic pericarditis	0.060	0.940	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.060	0.940	0.000
I09.0 Rheumatic myocarditis	0.060	0.940	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.060	0.940	0.000
I01.8 Other acute rheumatic heart disease	0.060	0.940	0.000
I01.2 Acute rheumatic myocarditis	0.060	0.940	0.000
I01.1 Acute rheumatic endocarditis	0.060	0.940	0.000
I01.0 Acute rheumatic pericarditis	0.060	0.940	0.000
I02.9 Rheumatic chorea without heart involvement	0.060	0.940	0.000
I02.0 Rheumatic chorea with heart involvement	0.060	0.940	0.000
I09.9 Rheumatic heart disease, unspecified	0.058	0.942	0.000
I06.0 Rheumatic aortic stenosis	0.058	0.942	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.058	0.942	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.057	0.943	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.056	0.943	0.000
I78.1 Naevus, nonneoplastic	0.056	0.944	0.000
I06.8 Other rheumatic aortic valve diseases	0.056	0.944	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.056	0.944	0.000
I74.8 Embolism and thrombosis of other arteries	0.056	0.944	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.055	0.945	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.054	0.946	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.054	0.946	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.054	0.946	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.054	0.946	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.052	0.948	0.000
I05.2 Mitral stenosis with insufficiency	0.051	0.949	0.000
I77 Other disorders of arteries and arterioles	0.051	0.949	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.050	0.949	0.000
I05.8 Other mitral valve diseases	0.050	0.949	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.050	0.949	0.000
I06.1 Rheumatic aortic insufficiency	0.049	0.951	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.047	0.952	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.047	0.953	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.047	0.953	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.046	0.954	0.000
I77.8 Other specified disorders of arteries and arterioles	0.046	0.954	0.000
I05.1 Rheumatic mitral insufficiency	0.045	0.954	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.045	0.955	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.045	0.955	0.000
I05.0 Mitral stenosis	0.045	0.955	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.044	0.955	0.000
N25-N29 Other disorders of kidney and ureter	0.044	0.956	0.000
I69 Sequelae of cerebrovascular disease	0.044	0.956	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.043	0.957	0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.043	0.957	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.041	0.958	0.001
I62.1 Nontraumatic extradural haemorrhage	0.041	0.959	0.000
I77.3 Arterial fibromuscular dysplasia	0.041	0.959	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.040	0.960	0.000
I77.2 Rupture of artery	0.040	0.960	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.039	0.960	0.001
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.039	0.961	0.000
N26 Unspecified contracted kidney	0.037	0.963	0.000
I65.2 Occlusion and stenosis of carotid artery	0.037	0.963	0.000
I77.5 Necrosis of artery	0.037	0.963	0.000
I77.4 Coeliac artery compression syndrome	0.037	0.963	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.036	0.964	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.036	0.964	0.000
I73 Other peripheral vascular diseases	0.033	0.967	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.032	0.968	0.000
I05.9 Mitral valve disease, unspecified	0.032	0.968	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.032	0.968	0.000
N25 Disorders resulting from impaired renal tubular function	0.032	0.968	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.032	0.968	0.000
I87 Other disorders of veins	0.031	0.969	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.031	0.969	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.030	0.969	0.001
I77.0 Arteriovenous fistula, acquired	0.031	0.969	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.030	0.970	0.000
N28.8 Other specified disorders of kidney and ureter	0.030	0.970	0.000
I74.5 Embolism and thrombosis of iliac artery	0.029	0.970	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.029	0.970	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.029	0.971	0.000
I82 Other venous embolism and thrombosis	0.028	0.972	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.026	0.973	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.026	0.974	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.026	0.974	0.000
N29.0 Late syphilis of kidney	0.026	0.974	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.026	0.974	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.026	0.974	0.000
N27 Small kidney of unknown cause	0.025	0.974	0.000
I88 Nonspecific lymphadenitis	0.025	0.975	0.000
I87.8 Other specified disorders of veins	0.025	0.975	0.000
I69.3 Sequelae of cerebral infarction	0.024	0.976	0.000
I81 Portal vein thrombosis	0.024	0.976	0.000
N25.0 Renal osteodystrophy	0.023	0.976	0.000
I63.9 Cerebral infarction, unspecified	0.024	0.976	0.000
I73.8 Other specified peripheral vascular diseases	0.023	0.977	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.023	0.977	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.023	0.977	0.000
M17.9 Gonarthrosis, unspecified	0.000	0.977	0.023
I82.3 Embolism and thrombosis of renal vein	0.023	0.977	0.000
I82.8 Embolism and thrombosis of other specified veins	0.023	0.977	0.000
I87.0 Postphlebitic syndrome	0.023	0.977	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.022	0.978	0.000
I87.1 Compression of vein	0.022	0.978	0.000
N25.1 Nephrogenic diabetes insipidus	0.021	0.978	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.021	0.979	0.000
I28 Other diseases of pulmonary vessels	0.020	0.979	0.001
I82.2 Embolism and thrombosis of vena cava	0.021	0.979	0.000
I88.8 Other nonspecific lymphadenitis	0.020	0.980	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.020	0.980	0.000
I82.1 Thrombophlebitis migrans	0.020	0.980	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.019	0.981	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.019	0.981	0.000
N27.1 Small kidney, bilateral	0.018	0.981	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.018	0.982	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.017	0.982	0.000
I82.0 Budd-Chiari syndrome	0.017	0.982	0.000
I77.6 Arteritis, unspecified	0.017	0.983	0.000
N27.0 Small kidney, unilateral	0.016	0.983	0.000
I85 Oesophageal varices	0.016	0.984	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.016	0.984	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.984	0.016
N27.9 Small kidney, unspecified	0.015	0.984	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.015	0.985	0.001
I89.1 Lymphangitis	0.015	0.985	0.000
I87.9 Disorder of vein, unspecified	0.015	0.985	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.014	0.985	0.001
I28.1 Aneurysm of pulmonary artery	0.014	0.985	0.001
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.015	0.985	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.014	0.985	0.000
S02.20 Fracture of nasal bones (closed)	0.014	0.986	0.000
I83 Varicose veins of lower extremities	0.014	0.986	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.013	0.986	0.000
I80 Phlebitis and thrombophlebitis	0.013	0.987	0.000
I28.8 Other specified diseases of pulmonary vessels	0.012	0.987	0.001
I80.8 Phlebitis and thrombophlebitis of other sites	0.013	0.987	0.000
I97.1 Other functional disturbances following cardiac surgery	0.012	0.988	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.989	0.011
D35.1 Parathyroid gland	0.011	0.989	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.011	0.989	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.011	0.989	0.000
I97.0 Postcardiotomy syndrome	0.011	0.989	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.011	0.989	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.011	0.989	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.011	0.989	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.010	0.989	0.000
I85.0 Oesophageal varices with bleeding	0.010	0.990	0.000
I99 Other and unspecified disorders of circulatory system	0.010	0.990	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.010	0.990	0.000
I26 Pulmonary embolism	0.009	0.991	0.001
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.009	0.991	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.009	0.991	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.008	0.992	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.008	0.992	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
I98.0 Cardiovascular syphilis	0.008	0.992	0.000
I86 Varicose veins of other sites	0.007	0.992	0.001
I85.9 Oesophageal varices without bleeding	0.007	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.007	0.993	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.993	0.007
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.007	0.993	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.007	0.993	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.007	0.993	0.000
S02.2 Fracture of nasal bones	0.007	0.993	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.007	0.993	0.000
D35.0 Adrenal gland	0.007	0.993	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.993	0.007
T78.3 Angioneurotic oedema	0.007	0.993	0.000
Q61 Cystic kidney disease	0.000	0.993	0.007
Q61.3 Polycystic kidney, unspecified	0.000	0.993	0.007
Q61.0 Congenital single renal cyst	0.000	0.994	0.006
D26.1 Corpus uteri	0.006	0.994	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.006	0.994	0.000
D26.0 Cervix uteri	0.006	0.994	0.000
I86.2 Pelvic varices	0.005	0.994	0.001
T78.8 Other adverse effects, not elsewhere classified	0.006	0.994	0.000
R49.0 Dysphonia	0.000	0.994	0.006
I86.0 Sublingual varices	0.005	0.994	0.001
I86.3 Vulval varices	0.005	0.994	0.001
T78.2 Anaphylactic shock, unspecified	0.006	0.994	0.000
T78.4 Allergy, unspecified	0.006	0.994	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.006	0.994	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.006	0.994	0.000
D26 Other benign neoplasms of uterus	0.005	0.995	0.000
D35.9 Endocrine gland, unspecified	0.005	0.995	0.000
D35.8 Pluriglandular involvement	0.005	0.995	0.000
D35.7 Other specified endocrine glands	0.005	0.995	0.000
D35.6 Aortic body and other paraganglia	0.005	0.995	0.000
D35.5 Carotid body	0.005	0.995	0.000
D35.4 Pineal gland	0.005	0.995	0.000
D35.3 Craniopharyngeal duct	0.005	0.995	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.995	0.005
S02.21 Fracture of nasal bones (open)	0.005	0.995	0.000
Q61.4 Renal dysplasia	0.000	0.995	0.005
T78.9 Adverse effect, unspecified	0.005	0.995	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.004	0.995	0.001
M17 Gonarthrosis [arthrosis of knee]	0.000	0.995	0.005
I27 Other pulmonary heart diseases	0.003	0.995	0.002
Q61.8 Other cystic kidney diseases	0.000	0.995	0.005
Q61.1 Polycystic kidney, infantile type	0.000	0.995	0.005
I95 Hypotension	0.005	0.995	0.000
D35.2 Pituitary gland	0.005	0.995	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.005	0.995	0.000
J38.4 Oedema of larynx	0.005	0.995	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.005	0.995	0.000
Q61.5 Medullary cystic kidney	0.000	0.995	0.005
D26.9 Uterus, unspecified	0.005	0.995	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.995	0.005
I86.8 Varicose veins of other specified sites	0.004	0.995	0.001
M21.1 Varus deformity, not elsewhere classified	0.000	0.996	0.004
S06.20 Diffuse brain injury (without open intracranial wound)	0.004	0.996	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.004	0.996	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.996	0.004
H60.9 Otitis externa, unspecified	0.000	0.996	0.004
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
M17.5 Other secondary gonarthrosis	0.000	0.996	0.004
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
D26.7 Other parts of uterus	0.004	0.996	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.000	0.996	0.004
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.004	0.996	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.996	0.004
I95.8 Other hypotension	0.004	0.996	0.000
J06.0 Acute laryngopharyngitis	0.000	0.996	0.004
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.996	0.002
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.996	0.004
J38.2 Nodules of vocal cords	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
J38.6 Stenosis of larynx	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.001	0.996	0.003
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
I95.2 Hypotension due to drugs	0.004	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.996	0.004
Z43.3 Attention to colostomy	0.004	0.996	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.996	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.996	0.003
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.996	0.003
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.996	0.003
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.996	0.003
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.996	0.003
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.996	0.003
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.996	0.003
Z85.6 Personal history of leukaemia	0.000	0.997	0.003
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.997	0.003
H74.4 Polyp of middle ear	0.000	0.997	0.003
I27.0 Primary pulmonary hypertension	0.000	0.997	0.003
Q60-Q64 Congenital malformations of the urinary system	0.000	0.997	0.003
I86.4 Gastric varices	0.003	0.997	0.001
S06.2 Diffuse brain injury	0.003	0.997	0.000
I27.9 Pulmonary heart disease, unspecified	0.001	0.997	0.002
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
J38.0 Paralysis of vocal cords and larynx	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.003	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.003	0.997	0.000
H60 Otitis externa	0.000	0.997	0.003
I95.0 Idiopathic hypotension	0.003	0.997	0.000
J38.3 Other diseases of vocal cords	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.000	0.997	0.003
H60.4 Cholesteatoma of external ear	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
H74.1 Adhesive middle ear disease	0.000	0.997	0.003
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.997	0.003
I77.1 Stricture of artery	0.003	0.997	0.000
S06.4 Epidural haemorrhage	0.003	0.997	0.000
I20-I25 Ischaemic heart diseases	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.997	0.003
R49 Voice disturbances	0.000	0.997	0.003
H74 Other disorders of middle ear and mastoid	0.000	0.997	0.003
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
O03.9 Complete or unspecified, without complication	0.000	0.997	0.003
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.997	0.003
I73.0 Raynaud's syndrome	0.003	0.997	0.000
H61 Other disorders of external ear	0.000	0.997	0.003
H72.8 Other perforations of tympanic membrane	0.000	0.997	0.003
H60.3 Other infective otitis externa	0.000	0.997	0.003
H60-H62 Diseases of external ear	0.000	0.997	0.003
H61.9 Disorder of external ear, unspecified	0.000	0.997	0.003
R49.8 Other and unspecified voice disturbances	0.000	0.997	0.003
I89.0 Lymphoedema, not elsewhere classified	0.002	0.997	0.001
M75.0 Adhesive capsulitis of shoulder	0.000	0.997	0.003
S06.21 Diffuse brain injury (with open intracranial wound)	0.003	0.997	0.000
L03.9 Cellulitis, unspecified	0.003	0.997	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.997	0.003
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.003	0.997	0.000
H60.8 Other otitis externa	0.000	0.997	0.002
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.997	0.002
Q64.8 Other specified congenital malformations of urinary system	0.000	0.997	0.002
Q64.6 Congenital diverticulum of bladder	0.000	0.997	0.002
Q64.5 Congenital absence of bladder and urethra	0.000	0.997	0.002
Q64.2 Congenital posterior urethral valves	0.000	0.997	0.002
Q64.1 Exstrophy of urinary bladder	0.000	0.997	0.002
Q64.0 Epispadias	0.000	0.997	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.997	0.002
Q60.3 Renal hypoplasia, unilateral	0.000	0.997	0.002
T70 Effects of air pressure and water pressure	0.002	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.001	0.998	0.001
H60.1 Cellulitis of external ear	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.000	0.998	0.002
S06.0 Concussion	0.002	0.998	0.000
I86.1 Scrotal varices	0.001	0.998	0.001
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.001
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
T75 Effects of other external causes	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.000	0.998	0.002
Q64.4 Malformation of urachus	0.000	0.998	0.002
T31.0 Burns involving less than 10% of body surface	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.002
J38.7 Other diseases of larynx	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.000	0.998	0.002
Q60.5 Renal hypoplasia, unspecified	0.000	0.998	0.002
Q60.4 Renal hypoplasia, bilateral	0.000	0.998	0.002
Q60.1 Renal agenesis, bilateral	0.000	0.998	0.002
Z52.4 Kidney donor	0.002	0.998	0.000
T74 Maltreatment syndromes	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.998	0.002
N72 Inflammatory disease of cervix uteri	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
T66 Unspecified effects of radiation	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
W19.3 Sports and athletics area	0.000	0.998	0.002
T73 Effects of other deprivation	0.002	0.998	0.000
O20.0 Threatened abortion	0.000	0.998	0.002
T70.3 Caisson disease [decompression sickness]	0.002	0.998	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.998	0.002
H02.0 Entropion and trichiasis of eyelid	0.002	0.998	0.000
H11.0 Pterygium	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
I22.8 Subsequent myocardial infarction of other sites	0.002	0.998	0.000
T75.4 Effects of electric current	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
Z52.3 Bone marrow donor	0.002	0.998	0.000
I22 Subsequent myocardial infarction	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.002	0.998	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.002	0.998	0.000
I23 Certain current complications following acute myocardial infarction	0.002	0.998	0.000
T68 Hypothermia	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
K80.4 Calculus of bile duct with cholecystitis	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.998	0.002
H11 Other disorders of conjunctiva	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.998	0.000
H60.0 Abscess of external ear	0.000	0.998	0.002
N39.8 Other specified disorders of urinary system	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.998	0.002
Q62.6 Malposition of ureter	0.000	0.998	0.002
Q62.5 Duplication of ureter	0.000	0.998	0.002
Q62.4 Agenesis of ureter	0.000	0.998	0.002
Q62.0 Congenital hydronephrosis	0.000	0.998	0.002
H11.8 Other specified disorders of conjunctiva	0.002	0.998	0.000
H11.3 Conjunctival haemorrhage	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.002	0.998	0.000
T70.8 Other effects of air pressure and water pressure	0.002	0.998	0.000
T70.4 Effects of high-pressure fluids	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations