TreeWAS – Variant ID: rs12652777

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.2 Primary angle-closure glaucoma	0.172	0.828	0.000
M10.96 Gout, unspecified (Lower leg)	0.017	0.983	0.000
K12.3 Oral mucositis (ulcerative)	0.016	0.984	0.000
H40 Glaucoma	0.016	0.984	0.000
K12.0 Recurrent oral aphthae	0.015	0.985	0.000
K12 Stomatitis and related lesions	0.015	0.985	0.000
I31.9 Disease of pericardium, unspecified	0.015	0.985	0.000
K12.2 Cellulitis and abscess of mouth	0.014	0.986	0.000
H40.0 Glaucoma suspect	0.013	0.987	0.000
F17.2 Dependence syndrome	0.000	0.988	0.012
H40.3 Glaucoma secondary to eye trauma	0.012	0.988	0.000
H40.6 Glaucoma secondary to drugs	0.011	0.988	0.000
H40.8 Other glaucoma	0.011	0.989	0.000
M67.8 Other specified disorders of synovium and tendon	0.011	0.989	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.000	0.989	0.011
K83.1 Obstruction of bile duct	0.011	0.989	0.000
S61.0 Open wound of finger(s) without damage to nail	0.011	0.989	0.000
G90.3 Multisystem degeneration	0.010	0.990	0.000
H40.5 Glaucoma secondary to other eye disorders	0.010	0.990	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.009	0.991	0.000
M10.9 Gout, unspecified	0.009	0.991	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.009	0.991	0.000
G90.2 Horner's syndrome	0.009	0.991	0.000
I87.8 Other specified disorders of veins	0.009	0.991	0.000
K12.1 Other forms of stomatitis	0.009	0.991	0.000
G90 Disorders of autonomic nervous system	0.009	0.991	0.000
H40.4 Glaucoma secondary to eye inflammation	0.008	0.992	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.008	0.992	0.000
Z93.0 Tracheostomy status	0.000	0.993	0.007
I31 Other diseases of pericardium	0.007	0.993	0.000
M10.98 Gout, unspecified (Other)	0.007	0.993	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M10.91 Gout, unspecified (Shoulder region)	0.007	0.993	0.000
M10.92 Gout, unspecified (Upper arm)	0.007	0.993	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.007	0.993	0.000
G90.8 Other disorders of autonomic nervous system	0.007	0.993	0.000
G90.4 Autonomic dysreflexia	0.006	0.993	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.006	0.993	0.000
H40-H42 Glaucoma	0.007	0.993	0.000
Q05.9 Spina bifida, unspecified	0.007	0.993	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.994	0.006
M10 Gout	0.006	0.994	0.000
B18.2 Chronic viral hepatitis C	0.006	0.994	0.000
M10.90 Gout, unspecified (Multiple sites)	0.006	0.994	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.994	0.006
M10.93 Gout, unspecified (Forearm)	0.006	0.994	0.000
I31.0 Chronic adhesive pericarditis	0.006	0.994	0.000
I31.1 Chronic constrictive pericarditis	0.006	0.994	0.000
M10.0 Idiopathic gout	0.006	0.994	0.000
M10.94 Gout, unspecified (Hand)	0.006	0.994	0.000
I31.8 Other specified diseases of pericardium	0.005	0.995	0.000
I31.2 Haemopericardium, not elsewhere classified	0.005	0.995	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.995	0.005
B18 Chronic viral hepatitis	0.005	0.995	0.000
D07.1 Vulva	0.000	0.995	0.005
M67 Other disorders of synovium and tendon	0.005	0.995	0.000
I31.3 Pericardial effusion (noninflammatory)	0.005	0.995	0.000
H42 Glaucoma in diseases classified elsewhere	0.005	0.995	0.000
M10.3 Gout due to impairment of renal function	0.005	0.995	0.000
M10.00 Idiopathic gout (Multiple sites)	0.005	0.995	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.005	0.995	0.000
M10.09 Idiopathic gout (Site unspecified)	0.005	0.995	0.000
K56.4 Other impaction of intestine	0.000	0.995	0.005
M10.02 Idiopathic gout (Upper arm)	0.005	0.995	0.000
M10.4 Other secondary gout	0.005	0.995	0.000
M10.2 Drug-induced gout	0.005	0.995	0.000
M10.1 Lead-induced gout	0.005	0.995	0.000
M10.04 Idiopathic gout (Hand)	0.005	0.995	0.000
D07.2 Vagina	0.000	0.995	0.005
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.996	0.004
Q05 Spina bifida	0.004	0.996	0.000
M10.08 Idiopathic gout (Other)	0.004	0.996	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.03 Idiopathic gout (Forearm)	0.004	0.996	0.000
M10.01 Idiopathic gout (Shoulder region)	0.004	0.996	0.000
B18.9 Chronic viral hepatitis, unspecified	0.004	0.996	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.004	0.996	0.000
I87 Other disorders of veins	0.004	0.996	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.004	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.004	0.996	0.000
B18.8 Other chronic viral hepatitis	0.004	0.996	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.004	0.996	0.000
M47.2 Other spondylosis with radiculopathy	0.004	0.996	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.996	0.004
M10.39 Gout due to impairment of renal function (Site unspecified)	0.004	0.996	0.000
M67.0 Short Achilles tendon (acquired)	0.004	0.996	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.004	0.996	0.000
M67.3 Transient synovitis	0.004	0.996	0.000
H40.1 Primary open-angle glaucoma	0.004	0.996	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.004	0.996	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
M10.38 Gout due to impairment of renal function (Other)	0.004	0.996	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.004	0.996	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.004	0.996	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.004	0.996	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.004	0.996	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.004	0.996	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.004	0.996	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.004	0.996	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
M10.06 Idiopathic gout (Lower leg)	0.003	0.996	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.004	0.996	0.000
M10.19 Lead-induced gout (Site unspecified)	0.003	0.996	0.000
M10.18 Lead-induced gout (Other)	0.003	0.996	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.003	0.996	0.000
M10.16 Lead-induced gout (Lower leg)	0.003	0.996	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.003	0.996	0.000
M10.14 Lead-induced gout (Hand)	0.003	0.996	0.000
M10.13 Lead-induced gout (Forearm)	0.003	0.996	0.000
M10.12 Lead-induced gout (Upper arm)	0.003	0.996	0.000
M10.11 Lead-induced gout (Shoulder region)	0.003	0.996	0.000
M10.10 Lead-induced gout (Multiple sites)	0.003	0.996	0.000
M10.29 Drug-induced gout (Site unspecified)	0.003	0.996	0.000
M10.28 Drug-induced gout (Other)	0.003	0.996	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.003	0.996	0.000
M10.26 Drug-induced gout (Lower leg)	0.003	0.996	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.003	0.996	0.000
M10.24 Drug-induced gout (Hand)	0.003	0.996	0.000
M10.23 Drug-induced gout (Forearm)	0.003	0.996	0.000
M10.22 Drug-induced gout (Upper arm)	0.003	0.996	0.000
M10.21 Drug-induced gout (Shoulder region)	0.003	0.996	0.000
M10.20 Drug-induced gout (Multiple sites)	0.003	0.996	0.000
M10.49 Other secondary gout (Site unspecified)	0.003	0.996	0.000
M10.48 Other secondary gout (Other)	0.003	0.996	0.000
M10.47 Other secondary gout (Ankle and foot)	0.003	0.996	0.000
M10.46 Other secondary gout (Lower leg)	0.003	0.996	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.003	0.996	0.000
M10.44 Other secondary gout (Hand)	0.003	0.996	0.000
M10.43 Other secondary gout (Forearm)	0.003	0.996	0.000
M10.42 Other secondary gout (Upper arm)	0.003	0.996	0.000
M10.41 Other secondary gout (Shoulder region)	0.003	0.996	0.000
M10.40 Other secondary gout (Multiple sites)	0.003	0.996	0.000
M67.1 Other contracture of tendon (sheath)	0.004	0.996	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.004	0.996	0.000
M67.4 Ganglion	0.004	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.996	0.000
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.003	0.997	0.000
B15-B19 Viral hepatitis	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.003	0.997	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.003	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.997	0.003
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.997	0.003
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.003	0.997	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.003	0.997	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.003	0.997	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.003	0.997	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
B15 Acute hepatitis A	0.003	0.997	0.000
D07.6 Other and unspecified male genital organs	0.000	0.997	0.003
D07.3 Other and unspecified female genital organs	0.000	0.997	0.003
D07.0 Endometrium	0.000	0.997	0.003
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.003	0.997	0.000
N90.4 Leukoplakia of vulva	0.000	0.997	0.003
B15.9 Hepatitis A without hepatic coma	0.003	0.997	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
D07.4 Penis	0.000	0.997	0.003
T82.1 Mechanical complication of cardiac electronic device	0.003	0.997	0.000
T82.3 Mechanical complication of other vascular grafts	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
M67.49 Ganglion, multiple sites	0.003	0.997	0.000
M67.45 Ganglion, hip	0.003	0.997	0.000
D07.5 Prostate	0.000	0.997	0.003
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.997	0.003
B17 Other acute viral hepatitis	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
F17.0 Acute intoxication	0.000	0.997	0.003
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.003	0.997	0.000
W57.0 Home	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.997	0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
M45 Ankylosing spondylitis	0.000	0.997	0.003
F17.3 Withdrawal state	0.000	0.997	0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.003	0.997	0.000
F17.8 Other mental and behavioural disorders	0.000	0.997	0.003
F17.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F17.6 Amnesic syndrome	0.000	0.997	0.003
F17.5 Psychotic disorder	0.000	0.997	0.003
F17.4 Withdrawal state with delirium	0.000	0.997	0.003
B16 Acute hepatitis B	0.003	0.997	0.000
C14.0 Pharynx, unspecified	0.000	0.997	0.003
B19 Unspecified viral hepatitis	0.003	0.997	0.000
I87.1 Compression of vein	0.003	0.997	0.000
B15.0 Hepatitis A with hepatic coma	0.002	0.997	0.000
B17.1 Acute hepatitis C	0.002	0.997	0.000
B17.2 Acute hepatitis E	0.002	0.997	0.000
F17.9 Unspecified mental and behavioural disorder	0.000	0.997	0.002
M67.43 Ganglion, wrist	0.002	0.998	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
B17.9 Acute viral hepatitis, unspecified	0.002	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.998	0.002
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.998	0.002
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.998	0.002
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.998	0.002
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.998	0.002
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.998	0.002
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.998	0.002
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.002	0.998	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.002	0.998	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
A02.0 Salmonella gastro-enteritis	0.002	0.998	0.000
B19.0 Unspecified viral hepatitis with coma	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
B17.8 Other specified acute viral hepatitis	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
B19.9 Unspecified viral hepatitis without coma	0.002	0.998	0.000
Z58.1 Exposure to air pollution	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.002	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.002	0.998	0.000
B08.1 Molluscum contagiosum	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
W55.0 Home	0.002	0.998	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.002
T82.0 Mechanical complication of heart valve prosthesis	0.002	0.998	0.000
N86 Erosion and ectropion of cervix uteri	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.002
I84.0 Internal thrombosed haemorrhoids	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
R44.3 Hallucinations, unspecified	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
O41.0 Oligohydramnios	0.000	0.998	0.002
R30.0 Dysuria	0.002	0.998	0.000
W18.3 Sports and athletics area	0.000	0.998	0.002
W57.8 Other specified place	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.998	0.002
G37.4 Subacute necrotising myelitis	0.000	0.998	0.002
G37.2 Central pontine myelinolysis	0.000	0.998	0.002
G37.1 Central demyelination of corpus callosum	0.000	0.998	0.002
G37.0 Diffuse sclerosis	0.000	0.998	0.002
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
R30.1 Vesical tenesmus	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.998	0.002
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.002	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.002	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.002	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.002
W13.9 Unspecified place	0.000	0.998	0.002
K42 Umbilical hernia	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
Z88.7 Personal history of allergy to serum and vaccine	0.002	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
W57.9 Unspecified place	0.002	0.998	0.000
W57.7 Farm	0.002	0.998	0.000
W57.6 Industrial and construction area	0.002	0.998	0.000
W57.5 Trade and service area	0.002	0.998	0.000
W57.4 Street and highway	0.002	0.998	0.000
W57.3 Sports and athletics area	0.002	0.998	0.000
W57.2 School, other institution and public administrative area	0.002	0.998	0.000
W57.1 Residential institution	0.002	0.998	0.000
M14.6 Neuropathic arthropathy	0.002	0.998	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
Q00.2 Iniencephaly	0.001	0.998	0.000
Q00.1 Craniorachischisis	0.001	0.998	0.000
Q00.0 Anencephaly	0.001	0.998	0.000
Q01.9 Encephalocele, unspecified	0.001	0.998	0.000
Q01.8 Encephalocele of other sites	0.001	0.998	0.000
Q01.2 Occipital encephalocele	0.001	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.001	0.998	0.000
Q01.0 Frontal encephalocele	0.001	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.998	0.002
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
R52.9 Pain, unspecified	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.001	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.001	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.998	0.002
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.998	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.998	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.998	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.998	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.998	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.998	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.998	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.998	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.998	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.998	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.001	0.998	0.000
Q06.4 Hydromyelia	0.001	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.001	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.001	0.998	0.000
Q06.0 Amyelia	0.001	0.998	0.000
R30.9 Painful micturition, unspecified	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
M14 Arthropathies in other diseases classified elsewhere	0.002	0.998	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.001	0.998	0.000
R30 Pain associated with micturition	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.000	0.998	0.002
K25.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
Q06.2 Diastematomyelia	0.001	0.998	0.000
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
W55 Bitten or struck by other mammals	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.001
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.001
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.001
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.998	0.000
W57.99 Bitten or stung by nonvenomous insect and other nonvenomous arthropods: Unspecified place: During unspecified activity	0.001	0.998	0.000
C05.1 Soft palate	0.001	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.001	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.001
Z64.0 Problems related to unwanted pregnancy	0.001	0.998	0.000
M13.0 Polyarthritis, unspecified	0.001	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.999	0.001
M14.8 Arthropathies in other specified diseases classified elsewhere	0.001	0.999	0.000
M88.9 Paget's disease of bone, unspecified	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
M14.2 Diabetic arthropathy	0.001	0.999	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.999	0.001
R60.1 Generalised oedema	0.001	0.999	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.999	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.001	0.999	0.000
M14.4 Arthropathy in amyloidosis	0.001	0.999	0.000
M14.3 Lipoid dermatoarthritis	0.001	0.999	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.001	0.999	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
W55.9 Unspecified place	0.001	0.999	0.000
W55.5 Trade and service area	0.001	0.999	0.000
W55.6 Industrial and construction area	0.001	0.999	0.000
W55.4 Street and highway	0.001	0.999	0.000
W55.3 Sports and athletics area	0.001	0.999	0.000
W55.2 School, other institution and public administrative area	0.001	0.999	0.000
W55.1 Residential institution	0.001	0.999	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.001	0.999	0.000
F41.1 Generalised anxiety disorder	0.000	0.999	0.001
J69.0 Pneumonitis due to food and vomit	0.000	0.999	0.001
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.999	0.001
W55.7 Farm	0.001	0.999	0.000
M02.39 Reiter's disease (Site unspecified)	0.000	0.999	0.001
M13.08 Polyarthritis, unspecified (Other)	0.001	0.999	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.001	0.999	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.001	0.999	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.001	0.999	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.001	0.999	0.000
W18.5 Trade and service area	0.000	0.999	0.001
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.001	0.999	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
H72.2 Other marginal perforations of tympanic membrane	0.001	0.999	0.000
Q63.0 Accessory kidney	0.001	0.999	0.000
M05-M14 Inflammatory polyarthropathies	0.001	0.999	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.001	0.999	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.001	0.999	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.001	0.999	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.001	0.999	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.001	0.999	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.001	0.999	0.000
L13.0 Dermatitis herpetiformis	0.000	0.999	0.001
R68.8 Other specified general symptoms and signs	0.000	0.999	0.001
W60.0 Home	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.999	0.001
K09.2 Other cysts of jaw	0.001	0.999	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.001	0.999	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.001	0.999	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.001	0.999	0.000
F80.1 Expressive language disorder	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
M05.1 Rheumatoid lung disease	0.001	0.999	0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.999	0.001
Z11.0 Special screening examination for intestinal infectious diseases	0.001	0.999	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.999	0.001
M08 Juvenile arthritis	0.001	0.999	0.000
W18 Other fall on same level	0.000	0.999	0.001
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.999	0.000
M08.2 Juvenile arthritis with systemic onset	0.001	0.999	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.001	0.999	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.999	0.001
A02.1 Salmonella septicaemia	0.001	0.999	0.000
C82.0 Small cleaved cell, follicular	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations