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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12662228
log Bayes Factor = 11.7641
Chromosome 6   position 55,191,559  (GRCh37) Explore rs12662228 on Ensembl!
Variant rs12662228 is part of Cluster X0223

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
A41 Other septicaemia
0.999 0.001 0.000
Y43 Primarily systemic agents
0.999 0.001 0.000
Y43.3 Other antineoplastic drugs
0.998 0.002 0.000
J90-J94 Other diseases of pleura
0.998 0.002 0.000
J90 Pleural effusion, not elsewhere classified
0.998 0.002 0.000
A41.9 Septicaemia, unspecified
0.996 0.004 0.000
V20-V29 Motorcycle rider injured in transport accident
0.985 0.015 0.000
S60-S69 Injuries to the wrist and hand
0.984 0.016 0.000
S40-S49 Injuries to the shoulder and upper arm
0.977 0.023 0.000
T66-T78 Other and unspecified effects of external causes
0.976 0.024 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.975 0.025 0.000
S62 Fracture at wrist and hand level
0.973 0.027 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.972 0.028 0.000
V23.4 Driver injured in traffic accident
0.967 0.033 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.965 0.035 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.962 0.038 0.000
J95-J99 Other diseases of the respiratory system
0.959 0.041 0.000
S62.6 Fracture of other finger
0.956 0.044 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.951 0.049 0.000
S62.60 Fracture of other finger (closed)
0.950 0.050 0.000
Y40 Systemic antibiotics
0.950 0.050 0.000
T78 Adverse effects, not elsewhere classified
0.944 0.056 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.941 0.059 0.000
B35-B49 Mycoses
0.940 0.060 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.937 0.063 0.000
J98 Other respiratory disorders
0.936 0.064 0.000
S90-S99 Injuries to the ankle and foot
0.932 0.068 0.000
S70-S79 Injuries to the hip and thigh
0.930 0.070 0.000
O60-O75 Complications of labour and delivery
0.918 0.082 0.000
S40 Superficial injury of shoulder and upper arm
0.904 0.096 0.000
B95-B98 Bacterial, viral and other infectious agents
0.897 0.103 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.895 0.105 0.000
M80-M85 Disorders of bone density and structure
0.893 0.107 0.000
S41 Open wound of shoulder and upper arm
0.892 0.108 0.000
S72 Fracture of femur
0.891 0.109 0.000
T78.4 Allergy, unspecified
0.890 0.110 0.000
M50-M54 Other dorsopathies
0.887 0.113 0.000
J09-J18 Influenza and pneumonia
0.886 0.114 0.000
B37 Candidiasis
0.885 0.115 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.879 0.121 0.000
S60 Superficial injury of wrist and hand
0.878 0.122 0.000
Y84.8 Other medical procedures
0.877 0.123 0.000
J80 Adult respiratory distress syndrome
0.875 0.125 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.873 0.127 0.000
M54 Dorsalgia
0.872 0.128 0.000
W00-W19 Falls
0.872 0.128 0.000
S68 Traumatic amputation of wrist and hand
0.869 0.131 0.000
M40-M43 Deforming dorsopathies
0.866 0.134 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.865 0.135 0.000
J91 Pleural effusion in conditions classified elsewhere
0.860 0.140 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.858 0.142 0.000
S62.4 Multiple fractures of metacarpal bones
0.858 0.142 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.856 0.144 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.856 0.144 0.000
J60-J70 Lung diseases due to external agents
0.855 0.145 0.000
W20-W49 Exposure to inanimate mechanical forces
0.854 0.145 0.000
O63 Long labour
0.853 0.147 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.850 0.150 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.848 0.152 0.000
O00-O08 Pregnancy with abortive outcome
0.846 0.154 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.844 0.156 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.844 0.156 0.000
Y40.9 Systemic antibiotic, unspecified
0.844 0.156 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.843 0.157 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.843 0.157 0.000
J98.1 Pulmonary collapse
0.842 0.158 0.000
M05-M14 Inflammatory polyarthropathies
0.840 0.160 0.000
B37.9 Candidiasis, unspecified
0.838 0.162 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.832 0.168 0.000
T68 Hypothermia
0.826 0.174 0.000
O66 Other obstructed labour
0.825 0.175 0.000
J98.4 Other disorders of lung
0.825 0.175 0.000
W75-W84 Other accidental threats to breathing
0.823 0.177 0.000
W50-W64 Exposure to animate mechanical forces
0.816 0.184 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
S72.0 Fracture of neck of femur
0.813 0.187 0.000
S41.1 Open wound of upper arm
0.812 0.188 0.000
M54.9 Dorsalgia, unspecified
0.811 0.189 0.000
T78.3 Angioneurotic oedema
0.806 0.194 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.805 0.195 0.000
Y84.6 Urinary catheterisation
0.803 0.197 0.000
S62.2 Fracture of first metacarpal bone
0.803 0.197 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.797 0.203 0.000
A49 Bacterial infection of unspecified site
0.795 0.205 0.000
M54.5 Low back pain
0.795 0.205 0.000
S67 Crushing injury of wrist and hand
0.792 0.208 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.791 0.209 0.000
A48 Other bacterial diseases, not elsewhere classified
0.789 0.210 0.000
O63.9 Long labour, unspecified
0.789 0.211 0.000
O63.0 Prolonged first stage (of labour)
0.788 0.212 0.000
S72.1 Pertrochanteric fracture
0.788 0.212 0.000
Y84.2 Radiological procedure and radiotherapy
0.788 0.212 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.787 0.213 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.787 0.213 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.787 0.213 0.000
Y40.8 Other systemic antibiotics
0.786 0.214 0.000
S20-S29 Injuries to the thorax
0.786 0.214 0.000
J81 Pulmonary oedema
0.785 0.215 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.783 0.217 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.783 0.217 0.000
J17 Pneumonia in diseases classified elsewhere
0.782 0.218 0.000
M84 Disorders of continuity of bone
0.781 0.219 0.000
A46 Erysipelas
0.780 0.220 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.779 0.221 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.779 0.221 0.000
D80-D89 Certain disorders involving the immune mechanism
0.779 0.221 0.000
M86-M90 Other osteopathies
0.778 0.222 0.000
Y84.9 Medical procedure, unspecified
0.777 0.223 0.000
S62.40 Multiple fractures of metacarpal bones (closed)
0.776 0.224 0.000
M91-M94 Chondropathies
0.774 0.226 0.000
Y46.2 Hydantoin derivatives
0.773 0.227 0.000
V40-V49 Car occupant injured in transport accident
0.773 0.227 0.000
A65-A69 Other spirochaetal diseases
0.772 0.228 0.000
B44 Aspergillosis
0.769 0.231 0.000
S40.0 Contusion of shoulder and upper arm
0.768 0.232 0.000
S72.2 Subtrochanteric fracture
0.768 0.232 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.767 0.233 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.766 0.234 0.000
S92 Fracture of foot, except ankle
0.764 0.236 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.760 0.240 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.760 0.240 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.757 0.243 0.000
S90 Superficial injury of ankle and foot
0.757 0.243 0.000
S72.00 Fracture of neck of femur (closed)
0.757 0.243 0.000
Y47.1 Benzodiazepines
0.757 0.243 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.756 0.244 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.756 0.244 0.000
S60.2 Contusion of other parts of wrist and hand
0.755 0.245 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.754 0.246 0.000
M20-M25 Other joint disorders
0.753 0.247 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.753 0.247 0.000
Y43.4 Immunosuppressive agents
0.751 0.249 0.000
T79-T79 Certain early complications of trauma
0.751 0.249 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.751 0.249 0.000
D86 Sarcoidosis
0.750 0.250 0.000
Chapter II Neoplasms
0.749 0.251 0.000
J84 Other interstitial pulmonary diseases
0.749 0.251 0.000
J20-J22 Other acute lower respiratory infections
0.748 0.252 0.000
M54.57 Low back pain (Lumbosacral region)
0.748 0.252 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.747 0.253 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.747 0.253 0.000
M54.1 Radiculopathy
0.747 0.253 0.000
B50-B64 Protozoal diseases
0.746 0.254 0.000
Y40.0 Penicillins
0.745 0.255 0.000
S91 Open wound of ankle and foot
0.743 0.257 0.000
O04 Medical abortion
0.742 0.258 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.739 0.260 0.000
A15-A19 Tuberculosis
0.739 0.261 0.000
M41 Scoliosis
0.739 0.261 0.000
S31 Open wound of abdomen, lower back and pelvis
0.738 0.262 0.000
Chapter VII Diseases of the eye and adnexa
0.737 0.263 0.000
B37.0 Candidal stomatitis
0.737 0.263 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.737 0.263 0.000
V10-V19 Pedal cyclist injured in transport accident
0.736 0.264 0.000
B15-B19 Viral hepatitis
0.736 0.264 0.000
D70 Agranulocytosis
0.735 0.265 0.000
M40 Kyphosis and lordosis
0.734 0.266 0.000
Y86 Sequelae of other accidents
0.734 0.266 0.000
M00-M03 Infectious arthropathies
0.734 0.266 0.000
M85 Other disorders of bone density and structure
0.734 0.266 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.732 0.268 0.000
B37.1 Pulmonary candidiasis
0.731 0.269 0.000
X20-X29 Contact with venomous animals and plants
0.730 0.270 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.729 0.270 0.000
S62.5 Fracture of thumb
0.728 0.271 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
A41.8 Other specified septicaemia
0.725 0.275 0.000
J98.9 Respiratory disorder, unspecified
0.725 0.275 0.000
Y83.0 Surgical operation with transplant of whole organ
0.724 0.276 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.724 0.276 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
M80 Osteoporosis with pathological fracture
0.723 0.277 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.723 0.277 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.721 0.279 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.720 0.280 0.000
M05 Seropositive rheumatoid arthritis
0.719 0.281 0.000
Y43.0 Antiallergic and antiemetic drugs
0.718 0.282 0.000
Y00-Y09 Assault
0.717 0.282 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Y59 Other and unspecified vaccines and biological substances
0.717 0.283 0.000
Y58 Bacterial vaccines
0.717 0.283 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.717 0.283 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A44 Bartonellosis
0.717 0.283 0.000
A43 Nocardiosis
0.717 0.283 0.000
A42 Actinomycosis
0.717 0.283 0.000
A39 Meningococcal infection
0.717 0.283 0.000
A37 Whooping cough
0.717 0.283 0.000
A36 Diphtheria
0.717 0.283 0.000
A32 Listeriosis
0.717 0.283 0.000
A31 Infection due to other mycobacteria
0.717 0.283 0.000
A30 Leprosy [Hansen's disease]
0.717 0.283 0.000
A38 Scarlet fever
0.717 0.283 0.000
A35 Other tetanus
0.717 0.283 0.000
A34 Obstetrical tetanus
0.717 0.283 0.000
A33 Tetanus neonatorum
0.717 0.283 0.000
A41.4 Septicaemia due to anaerobes
0.716 0.283 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.716 0.283 0.000
Y43.9 Primarily systemic agent, unspecified
0.716 0.284 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.716 0.284 0.000
Y43.6 Enzymes, not elsewhere classified
0.716 0.284 0.000
Y43.5 Acidifying and alkalising agents
0.716 0.284 0.000
Y43.2 Antineoplastic natural products
0.716 0.284 0.000
M25 Other joint disorders, not elsewhere classified
0.716 0.284 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
W11 Fall on and from ladder
0.715 0.285 0.000
J69 Pneumonitis due to solids and liquids
0.715 0.285 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.714 0.285 0.000
W21 Striking against or struck by sports equipment
0.714 0.286 0.000
S72.10 Pertrochanteric fracture (closed)
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.712 0.288 0.000
M54.6 Pain in thoracic spine
0.712 0.288 0.000
Y88 Sequelae of surgical and medical care as external cause
0.711 0.288 0.000
S62.7 Multiple fractures of fingers
0.709 0.291 0.000
A40 Streptococcal septicaemia
0.709 0.291 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.708 0.292 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
D55-D59 Haemolytic anaemias
0.707 0.293 0.000
W10 Fall on and from stairs and steps
0.707 0.293 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.706 0.294 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.706 0.294 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.706 0.294 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.706 0.294 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.706 0.294 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.706 0.294 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.706 0.294 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.706 0.294 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.706 0.294 0.000
S65 Injury of blood vessels at wrist and hand level
0.705 0.294 0.000
S60.8 Other superficial injuries of wrist and hand
0.705 0.295 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.704 0.295 0.000
M60-M63 Disorders of muscles
0.704 0.296 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.704 0.296 0.000
S41.0 Open wound of shoulder
0.702 0.298 0.000
X60-X84 Intentional self-harm
0.701 0.299 0.000
M65-M68 Disorders of synovium and tendon
0.701 0.299 0.000
S48 Traumatic amputation of shoulder and upper arm
0.700 0.300 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.700 0.300 0.000
S44 Injury of nerves at shoulder and upper arm level
0.700 0.300 0.000
S47 Crushing injury of shoulder and upper arm
0.700 0.300 0.000
T75 Effects of other external causes
0.700 0.300 0.000
T74 Maltreatment syndromes
0.700 0.300 0.000
T73 Effects of other deprivation
0.700 0.300 0.000
T70 Effects of air pressure and water pressure
0.700 0.300 0.000
T69 Other effects of reduced temperature
0.700 0.300 0.000
T67 Effects of heat and light
0.700 0.300 0.000
T71 Asphyxiation
0.700 0.300 0.000
T66 Unspecified effects of radiation
0.700 0.300 0.000
V23.9 Unspecified motorcycle rider injured in traffic accident
0.699 0.301 0.000
V23.5 Passenger injured in traffic accident
0.699 0.301 0.000
V23.3 Person injured while boarding or alighting
0.699 0.301 0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident
0.699 0.301 0.000
V23.1 Passenger injured in nontraffic accident
0.699 0.301 0.000
V23.0 Driver injured in nontraffic accident
0.699 0.301 0.000
Y83.8 Other surgical procedures
0.698 0.302 0.000
S62.1 Fracture of other carpal bone(s)
0.698 0.302 0.000
D86.9 Sarcoidosis, unspecified
0.697 0.303 0.000
W78 Inhalation of gastric contents
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.695 0.305 0.000
L50-L54 Urticaria and erythema
0.695 0.305 0.000
Y65 Other misadventures during surgical and medical care
0.694 0.306 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.694 0.306 0.000
W13 Fall from, out of or through building or structure
0.694 0.306 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.693 0.306 0.000
M13 Other arthritis
0.693 0.307 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.693 0.307 0.000
M21 Other acquired deformities of limbs
0.692 0.308 0.000
O61 Failed induction of labour
0.691 0.309 0.000
Y84.4 Aspiration of fluid
0.691 0.309 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.690 0.310 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.689 0.311 0.000
S50-S59 Injuries to the elbow and forearm
0.689 0.311 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.689 0.311 0.000
W20 Struck by thrown, projected or falling object
0.688 0.312 0.000
W17 Other fall from one level to another
0.688 0.312 0.000
J96 Respiratory failure, not elsewhere classified
0.687 0.313 0.000
Y43.1 Antineoplastic antimetabolites
0.686 0.314 0.000
W15 Fall from cliff
0.686 0.314 0.000
M54.8 Other dorsalgia
0.686 0.314 0.000
S70 Superficial injury of hip and thigh
0.685 0.315 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.684 0.316 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.684 0.316 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.684 0.316 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.683 0.317 0.000
O73 Retained placenta and membranes, without haemorrhage
0.682 0.318 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.682 0.318 0.000
Y40.7 Antifungal antibiotics, systemically used
0.681 0.319 0.000
Y40.6 Rifamycins
0.681 0.319 0.000
Y40.5 Aminoglycosides
0.681 0.319 0.000
Y40.4 Tetracyclines
0.681 0.319 0.000
Y40.3 Macrolides
0.681 0.319 0.000
Y40.2 Chloramphenicol group
0.681 0.319 0.000
S62.20 Fracture of first metacarpal bone (closed)
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.680 0.320 0.000
O72 Postpartum haemorrhage
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
S72.20 Subtrochanteric fracture (closed)
0.679 0.321 0.000
H43-H45 Disorders of vitreous body and globe
0.679 0.321 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
T21 Burn and corrosion of trunk
0.678 0.322 0.000
W28 Contact with powered lawn mower
0.678 0.322 0.000
J93 Pneumothorax
0.678 0.322 0.000
S60.0 Contusion of finger(s) without damage to nail
0.678 0.322 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.678 0.322 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.677 0.323 0.000
Q60-Q64 Congenital malformations of the urinary system
0.677 0.323 0.000
Y84.1 Kidney dialysis
0.677 0.323 0.000
T91 Sequelae of injuries of neck and trunk
0.677 0.323 0.000
T78.9 Adverse effect, unspecified
0.677 0.323 0.000
T78.8 Other adverse effects, not elsewhere classified
0.677 0.323 0.000
Y84.7 Blood-sampling
0.675 0.325 0.000
Y84.5 Insertion of gastric or duodenal sound
0.675 0.325 0.000
Y84.3 Shock therapy
0.675 0.325 0.000
Y46.6 Other and unspecified antiepileptics
0.674 0.326 0.000
B48 Other mycoses, not elsewhere classified
0.674 0.326 0.000
B47 Mycetoma
0.674 0.326 0.000
B46 Zygomycosis
0.674 0.326 0.000
B45 Cryptococcosis
0.674 0.326 0.000
B43 Chromomycosis and phaeomycotic abscess
0.674 0.326 0.000
B42 Sporotrichosis
0.674 0.326 0.000
B41 Paracoccidioidomycosis
0.674 0.326 0.000
B40 Blastomycosis
0.674 0.326 0.000
B39 Histoplasmosis
0.674 0.326 0.000
B38 Coccidioidomycosis
0.674 0.326 0.000
B36 Other superficial mycoses
0.674 0.326 0.000
S71 Open wound of hip and thigh
0.673 0.327 0.000
J15.1 Pneumonia due to Pseudomonas
0.673 0.327 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.672 0.328 0.000
C15-C26 Malignant neoplasms of digestive organs
0.671 0.329 0.000
M25.4 Effusion of joint
0.671 0.329 0.000
T20 Burn and corrosion of head and neck
0.671 0.329 0.000
J98.3 Compensatory emphysema
0.671 0.329 0.000
J98.2 Interstitial emphysema
0.671 0.329 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.671 0.329 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.671 0.329 0.000
Y52 Agents primarily affecting the cardiovascular system
0.670 0.330 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.669 0.331 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.669 0.331 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.669 0.331 0.000
S98 Traumatic amputation of ankle and foot
0.668 0.331 0.000
S97 Crushing injury of ankle and foot
0.668 0.331 0.000
S95 Injury of blood vessels at ankle and foot level
0.668 0.331 0.000
S94 Injury of nerves at ankle and foot level
0.668 0.331 0.000
O04.9 Complete or unspecified, without complication
0.668 0.332 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.668 0.332 0.000
M11 Other crystal arthropathies
0.668 0.332 0.000
S78 Traumatic amputation of hip and thigh
0.667 0.333 0.000
S77 Crushing injury of hip and thigh
0.667 0.333 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.667 0.333 0.000
S75 Injury of blood vessels at hip and thigh level
0.667 0.333 0.000
S74 Injury of nerves at hip and thigh level
0.667 0.333 0.000
S14 Injury of nerves and spinal cord at neck level
0.666 0.334 0.000
T23 Burn and corrosion of wrist and hand
0.666 0.334 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.665 0.335 0.000
Q50-Q56 Congenital malformations of genital organs
0.664 0.336 0.000
M06 Other rheumatoid arthritis
0.664 0.336 0.000
J11 Influenza, virus not identified
0.663 0.337 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.663 0.337 0.000
Y48 Anaesthetics and therapeutic gases
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.662 0.338 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.661 0.339 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.661 0.339 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.660 0.340 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.660 0.340 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.660 0.340 0.000
Y57 Other and unspecified drugs and medicaments
0.659 0.340 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.659 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.659 0.341 0.000
O74 Complications of anaesthesia during labour and delivery
0.658 0.342 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.658 0.342 0.000
O60 Preterm delivery
0.658 0.342 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.658 0.342 0.000
C34 Malignant neoplasm of bronchus and lung
0.657 0.343 0.000
H18 Other disorders of cornea
0.655 0.345 0.000
A49.8 Other bacterial infections of unspecified site
0.655 0.345 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.655 0.345 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.654 0.346 0.000
B49 Unspecified mycosis
0.652 0.347 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.650 0.350 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.649 0.351 0.000
S40.7 Multiple superficial injuries of shoulder and upper arm
0.648 0.351 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.648 0.352 0.000
J10 Influenza due to identified influenza virus
0.646 0.354 0.000
M54.4 Lumbago with sciatica
0.644 0.356 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.643 0.357 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.643 0.357 0.000
O80-O84 Delivery
0.643 0.357 0.000
J17.2 Pneumonia in mycoses
0.643 0.357 0.000
Y41.0 Sulphonamides
0.642 0.357 0.000
B35 Dermatophytosis
0.642 0.357 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.642 0.358 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.641 0.359 0.000
M83 Adult osteomalacia
0.640 0.360 0.000
M40.2 Other and unspecified kyphosis
0.640 0.360 0.000
S69 Other and unspecified injuries of wrist and hand
0.640 0.360 0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle
0.639 0.360 0.000
S41.7 Multiple open wounds of shoulder and upper arm
0.639 0.360 0.000
S72.9 Fracture of femur, part unspecified
0.639 0.361 0.000
S72.8 Fractures of other parts of femur
0.639 0.361 0.000
S72.7 Multiple fractures of femur
0.639 0.361 0.000
A48.1 Legionnaires' disease
0.639 0.361 0.000
S99 Other and unspecified injuries of ankle and foot
0.639 0.361 0.000
B44.1 Other pulmonary aspergillosis
0.638 0.362 0.000
D86.8 Sarcoidosis of other and combined sites
0.637 0.363 0.000
S27 Injury of other and unspecified intrathoracic organs
0.637 0.363 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.635 0.364 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.635 0.365 0.000
J12 Viral pneumonia, not elsewhere classified
0.635 0.365 0.000
J09 Influenza due to certain identified influenza virus
0.635 0.365 0.000
B37.4 Candidiasis of other urogenital sites
0.635 0.365 0.000
B37.7 Candidal septicaemia
0.634 0.366 0.000
B37.6 Candidal endocarditis
0.634 0.366 0.000
B37.5 Candidal meningitis
0.634 0.366 0.000
B37.2 Candidiasis of skin and nail
0.634 0.366 0.000
O71 Other obstetric trauma
0.634 0.366 0.000
M54.16 Radiculopathy (Lumbar region)
0.634 0.366 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.633 0.367 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.633 0.367 0.000
M21.3 Wrist or foot drop (acquired)
0.633 0.367 0.000
O03 Spontaneous abortion
0.632 0.368 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.630 0.369 0.000
S42 Fracture of shoulder and upper arm
0.630 0.370 0.000
Y46.8 Antispasticity drugs
0.630 0.370 0.000
Y46.7 Anti-Parkinsonism drugs
0.630 0.370 0.000
Y46.5 Valproic acid
0.630 0.370 0.000
Y46.4 Iminostilbenes
0.630 0.370 0.000
Y46.3 Deoxybarbiturates
0.630 0.370 0.000
Y46.1 Oxazolidinediones
0.630 0.370 0.000
Y46.0 Succinimides
0.630 0.370 0.000
L20-L30 Dermatitis and eczema
0.630 0.370 0.000
S60.7 Multiple superficial injuries of wrist and hand
0.629 0.371 0.000
S60.1 Contusion of finger(s) with damage to nail
0.629 0.371 0.000
S36 Injury of intra-abdominal organs
0.629 0.371 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.629 0.371 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.629 0.371 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.628 0.372 0.000
M41.9 Scoliosis, unspecified
0.627 0.373 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.626 0.374 0.000
O40 Polyhydramnios
0.626 0.374 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.626 0.374 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.626 0.374 0.000
Q35-Q37 Cleft lip and cleft palate
0.626 0.374 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.626 0.374 0.000
M54.0 Panniculitis affecting regions of neck and back
0.625 0.375 0.000
O00 Ectopic pregnancy
0.625 0.375 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.625 0.375 0.000
W14 Fall from tree
0.625 0.375 0.000
W12 Fall on and from scaffolding
0.625 0.375 0.000
W09 Fall involving playground equipment
0.625 0.375 0.000
W05 Fall involving wheelchair
0.625 0.375 0.000
W04 Fall while being carried or supported by other persons
0.625 0.375 0.000
W00 Fall on same level involving ice and snow
0.625 0.375 0.000
A80-A89 Viral infections of the central nervous system
0.625 0.375 0.000
J98.6 Disorders of diaphragm
0.624 0.376 0.000
C83.3 Large cell (diffuse)
0.624 0.376 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.623 0.377 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.623 0.377 0.000
S68.4 Traumatic amputation of hand at wrist level
0.623 0.377 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.623 0.377 0.000
L53 Other erythematous conditions
0.623 0.377 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.623 0.377 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.623 0.377 0.000
M94 Other disorders of cartilage
0.622 0.378 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.621 0.379 0.000
B65-B83 Helminthiases
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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