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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12680546
log Bayes Factor = <0.0001
Chromosome 8   position 136,871,739  (GRCh37) Explore rs12680546 on Ensembl!
Variant rs12680546 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.115 0.885 0.000
L81.4 Other melanin hyperpigmentation
0.000 0.990 0.010
M79.69 Pain in limb (Site unspecified)
0.000 0.990 0.010
M35.0 Sicca syndrome [Sjogren]
0.000 0.991 0.009
U80.1 Methicillin resistant agent
0.008 0.992 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.005 0.995 0.000
K70.9 Alcoholic liver disease, unspecified
0.005 0.995 0.000
K70.4 Alcoholic hepatic failure
0.005 0.995 0.000
K70.0 Alcoholic fatty liver
0.005 0.995 0.000
K70 Alcoholic liver disease
0.005 0.995 0.000
G63.2 Diabetic polyneuropathy
0.000 0.995 0.005
M54.59 Low back pain (Site unspecified)
0.000 0.996 0.004
K70.2 Alcoholic fibrosis and sclerosis of liver
0.004 0.996 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.004 0.996 0.000
K70.3 Alcoholic cirrhosis of liver
0.004 0.996 0.000
I45.1 Other and unspecified right bundle-branch block
0.004 0.996 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.004 0.996 0.000
C67.5 Bladder neck
0.000 0.997 0.003
C50.1 Central portion of breast
0.003 0.997 0.000
R11 Nausea and vomiting
0.000 0.997 0.003
K70.1 Alcoholic hepatitis
0.003 0.997 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.000 0.997 0.003
S49.9 Unspecified injury of shoulder and upper arm
0.000 0.997 0.003
F00 Dementia in Alzheimer's disease
0.003 0.997 0.000
G56.2 Lesion of ulnar nerve
0.000 0.997 0.003
C67.4 Posterior wall of bladder
0.000 0.997 0.003
X68.9 Unspecified place
0.003 0.997 0.000
L81 Other disorders of pigmentation
0.000 0.997 0.003
D31.3 Choroid
0.002 0.998 0.000
L81.9 Disorder of pigmentation, unspecified
0.000 0.998 0.002
H65.3 Chronic mucoid otitis media
0.002 0.998 0.000
C67 Malignant neoplasm of bladder
0.000 0.998 0.002
F00.1 Dementia in Alzheimer's disease with late onset
0.002 0.998 0.000
C67.1 Dome of bladder
0.000 0.998 0.002
M65.14 Other infective (teno)synovitis (Hand)
0.002 0.998 0.000
G43.1 Migraine with aura [classical migraine]
0.002 0.998 0.000
C67.2 Lateral wall of bladder
0.000 0.998 0.002
H00.0 Hordeolum and other deep inflammation of eyelid
0.002 0.998 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.998 0.002
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.002 0.998 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.998 0.002
C67.0 Trigone of bladder
0.000 0.998 0.002
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.002 0.998 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.002 0.998 0.000
G50.0 Trigeminal neuralgia
0.000 0.998 0.002
L81.6 Other disorders of diminished melanin formation
0.000 0.998 0.002
L81.5 Leukoderma, not elsewhere classified
0.000 0.998 0.002
L81.3 Cafe au lait spots
0.000 0.998 0.002
L81.1 Chloasma
0.000 0.998 0.002
C67.8 Overlapping lesion of bladder
0.000 0.998 0.002
D43.2 Brain, unspecified
0.000 0.998 0.002
M43.1 Spondylolisthesis
0.002 0.998 0.000
M43.12 Spondylolisthesis (Cervical region)
0.002 0.998 0.000
C67.7 Urachus
0.000 0.998 0.002
L81.2 Freckles
0.000 0.998 0.002
L81.0 Postinflammatory hyperpigmentation
0.000 0.998 0.002
T93.2 Sequelae of other fractures of lower limb
0.000 0.998 0.002
M43.19 Spondylolisthesis (Site unspecified)
0.002 0.998 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.998 0.002
I85.0 Oesophageal varices with bleeding
0.002 0.998 0.000
L81.7 Pigmented purpuric dermatosis
0.000 0.998 0.002
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.998 0.002
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.998 0.002
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.998 0.002
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.998 0.002
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.998 0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.998 0.002
G63.1 Polyneuropathy in neoplastic disease
0.000 0.998 0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.998 0.002
M07.3 Other psoriatic arthropathies
0.000 0.998 0.002
S10.9 Superficial injury of neck, part unspecified
0.002 0.998 0.000
N18.0 End-stage renal disease
0.000 0.998 0.002
S51.0 Open wound of elbow
0.000 0.998 0.002
U80 Agent resistant to penicillin and related antibiotics
0.002 0.998 0.000
S11.9 Open wound of neck, part unspecified
0.002 0.998 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.998 0.002
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.002 0.998 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.002 0.998 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.002 0.998 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.002 0.998 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.002 0.998 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.002 0.998 0.000
R81 Glycosuria
0.002 0.998 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.000 0.998 0.002
C67.3 Anterior wall of bladder
0.000 0.998 0.002
N02.9 Unspecified
0.002 0.998 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.002 0.998 0.000
D48.1 Connective and other soft tissue
0.002 0.998 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.002 0.998 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.000 0.998 0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.000 0.998 0.002
T93 Sequelae of injuries of lower limb
0.000 0.998 0.002
M07.38 Other psoriatic arthropathies (Other)
0.000 0.998 0.001
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.998 0.001
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.998 0.001
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.998 0.001
L81.8 Other specified disorders of pigmentation
0.001 0.998 0.001
N02.8 Other
0.002 0.998 0.000
T93.0 Sequelae of open wound of lower limb
0.000 0.998 0.002
R84.6 Abnormal cytological findings
0.001 0.998 0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)
0.000 0.998 0.002
J38.2 Nodules of vocal cords
0.000 0.998 0.002
N87.9 Dysplasia of cervix uteri, unspecified
0.000 0.998 0.002
B35.1 Tinea unguium
0.000 0.998 0.001
R84.5 Abnormal microbiological findings
0.001 0.998 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.001 0.998 0.000
H60.9 Otitis externa, unspecified
0.000 0.998 0.001
R86.8 Other abnormal findings
0.001 0.998 0.000
R86.7 Abnormal histological findings
0.001 0.998 0.000
C67.6 Ureteric orifice
0.000 0.999 0.001
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.999 0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.000 0.999 0.001
T93.1 Sequelae of fracture of femur
0.000 0.999 0.001
E89.0 Postprocedural hypothyroidism
0.001 0.999 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.001 0.999 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.999 0.001
M10.93 Gout, unspecified (Forearm)
0.001 0.999 0.000
O36.5 Maternal care for poor foetal growth
0.001 0.999 0.000
X68.8 Other specified place
0.001 0.999 0.000
X68.7 Farm
0.001 0.999 0.000
X68.6 Industrial and construction area
0.001 0.999 0.000
X68.5 Trade and service area
0.001 0.999 0.000
X68.4 Street and highway
0.001 0.999 0.000
X68.3 Sports and athletics area
0.001 0.999 0.000
X68.2 School, other institution and public administrative area
0.001 0.999 0.000
X68.1 Residential institution
0.001 0.999 0.000
X68.0 Home
0.001 0.999 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.001 0.999 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.000 0.999 0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.000 0.999 0.001
T93.4 Sequelae of injury of nerve of lower limb
0.000 0.999 0.001
R61.0 Localised hyperhidrosis
0.001 0.999 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.001 0.999 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.999 0.001
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.001 0.999 0.000
D31.0 Conjunctiva
0.001 0.999 0.000
E53.8 Deficiency of other specified B group vitamins
0.001 0.999 0.000
G56.3 Lesion of radial nerve
0.000 0.999 0.001
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.999 0.001
R87.9 Unspecified abnormal finding
0.001 0.999 0.000
M35 Other systemic involvement of connective tissue
0.000 0.999 0.001
C67.9 Bladder, unspecified
0.000 0.999 0.001
T23.2 Burn of second degree of wrist and hand
0.000 0.999 0.001
R86 Abnormal findings in specimens from male genital organs
0.001 0.999 0.000
C02.9 Tongue, unspecified
0.001 0.999 0.000
R82.4 Acetonuria
0.001 0.999 0.000
R86.5 Abnormal microbiological findings
0.001 0.999 0.000
D31 Benign neoplasm of eye and adnexa
0.001 0.999 0.000
D48.6 Breast
0.001 0.999 0.000
F64.0 Transsexualism
0.000 0.999 0.001
T92.2 Sequelae of fracture at wrist and hand level
0.000 0.999 0.001
N02 Recurrent and persistent haematuria
0.001 0.999 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.999 0.001
S72.40 Fracture of lower end of femur (closed)
0.000 0.999 0.001
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.001 0.999 0.000
R84.9 Unspecified abnormal finding
0.001 0.999 0.000
R84.8 Other abnormal findings
0.001 0.999 0.000
R84.7 Abnormal histological findings
0.001 0.999 0.000
R84.4 Abnormal immunological findings
0.001 0.999 0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances
0.001 0.999 0.000
R84.1 Abnormal level of hormones
0.001 0.999 0.000
R84.0 Abnormal level of enzymes
0.001 0.999 0.000
R89.5 Abnormal microbiological findings
0.001 0.999 0.000
S69.9 Unspecified injury of wrist and hand
0.000 0.999 0.001
T68 Hypothermia
0.000 0.999 0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.999 0.001
R14 Flatulence and related conditions
0.001 0.999 0.000
R80 Isolated proteinuria
0.001 0.999 0.000
A04.5 Campylobacter enteritis
0.000 0.999 0.001
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.999 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.999 0.001
M35.8 Other specified systemic involvement of connective tissue
0.000 0.999 0.001
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.999 0.001
M35.5 Multifocal fibrosclerosis
0.000 0.999 0.001
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.999 0.001
N02.0 Minor glomerular abnormality
0.001 0.999 0.000
R86.0 Abnormal level of enzymes
0.001 0.999 0.000
K83.8 Other specified diseases of biliary tract
0.001 0.999 0.000
R86.4 Abnormal immunological findings
0.001 0.999 0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances
0.001 0.999 0.000
R86.1 Abnormal level of hormones
0.001 0.999 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.001 0.999 0.000
D31.9 Eye, unspecified
0.001 0.999 0.000
D31.6 Orbit, unspecified
0.001 0.999 0.000
D31.5 Lachrymal gland and duct
0.001 0.999 0.000
D31.4 Ciliary body
0.001 0.999 0.000
D31.2 Retina
0.001 0.999 0.000
D31.1 Cornea
0.001 0.999 0.000
G58.8 Other specified mononeuropathies
0.000 0.999 0.001
N02.2 Diffuse membranous glomerulonephritis
0.001 0.999 0.000
O21.9 Vomiting of pregnancy, unspecified
0.000 0.999 0.001
T75.4 Effects of electric current
0.000 0.999 0.001
T91.1 Sequelae of fracture of spine
0.000 0.999 0.001
F31.0 Bipolar affective disorder, current episode hypomanic
0.001 0.999 0.000
N02.7 Diffuse crescentic glomerulonephritis
0.001 0.999 0.000
N02.6 Dense deposit disease
0.001 0.999 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.001 0.999 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.001 0.999 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.001 0.999 0.000
N02.1 Focal and segmental glomerular lesions
0.001 0.999 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.000 0.999 0.001
S10.1 Other and unspecified superficial injuries of throat
0.001 0.999 0.000
C74.9 Adrenal gland, unspecified
0.001 0.999 0.000
D23.4 Skin of scalp and neck
0.001 0.999 0.000
I49.1 Atrial premature depolarisation
0.001 0.999 0.000
I71.0 Dissection of aorta [any part]
0.000 0.999 0.001
M35.7 Hypermobility syndrome
0.000 0.999 0.001
M79.62 Pain in limb (Upper arm)
0.000 0.999 0.001
J93.8 Other pneumothorax
0.000 0.999 0.001
M35.2 Behcet's disease
0.000 0.999 0.001
R82.7 Abnormal findings on microbiological examination of urine
0.001 0.999 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.001 0.999 0.000
S10 Superficial injury of neck
0.001 0.999 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.999 0.001
D48.5 Skin
0.001 0.999 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.001 0.999 0.000
J84.8 Other specified interstitial pulmonary diseases
0.001 0.999 0.000
N76.4 Abscess of vulva
0.001 0.999 0.000
S11.7 Multiple open wounds of neck
0.001 0.999 0.000
Y85.0 Sequelae of motor-vehicle accident
0.000 0.999 0.001
G56 Mononeuropathies of upper limb
0.000 0.999 0.001
R82 Other abnormal findings in urine
0.001 0.999 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.001 0.999 0.000
G56.8 Other mononeuropathies of upper limb
0.000 0.999 0.001
H54.4 Blindness, one eye
0.001 0.999 0.000
H66.9 Otitis media, unspecified
0.001 0.999 0.000
O00.1 Tubal pregnancy
0.000 0.999 0.001
R46.2 Strange and inexplicable behaviour
0.001 0.999 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.001 0.999 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.001 0.999 0.000
S11 Open wound of neck
0.001 0.999 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.001 0.999 0.000
O69.8 Labour and delivery complicated by other cord complications
0.000 0.999 0.001
R20.0 Anaesthesia of skin
0.001 0.999 0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
R82.3 Haemoglobinuria
0.001 0.999 0.000
R82.2 Biliuria
0.001 0.999 0.000
R82.0 Chyluria
0.001 0.999 0.000
R86.9 Unspecified abnormal finding
0.001 0.999 0.000
R86.6 Abnormal cytological findings
0.001 0.999 0.000
R89.9 Unspecified abnormal finding
0.001 0.999 0.000
R89.8 Other abnormal findings
0.001 0.999 0.000
R89.7 Abnormal histological findings
0.001 0.999 0.000
R89.6 Abnormal cytological findings
0.001 0.999 0.000
R89.4 Abnormal immunological findings
0.001 0.999 0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances
0.001 0.999 0.000
R89.1 Abnormal level of hormones
0.001 0.999 0.000
R89.0 Abnormal level of enzymes
0.001 0.999 0.000
S10.7 Multiple superficial injuries of neck
0.001 0.999 0.000
S10.0 Contusion of throat
0.001 0.999 0.000
S30.0 Contusion of lower back and pelvis
0.001 0.999 0.000
X23.9 Unspecified place
0.001 0.999 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.001 0.999 0.000
Z74.8 Other problems related to care-provider dependency
0.001 0.999 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.000 0.999 0.001
C75.0 Parathyroid gland
0.001 0.999 0.000
D26.1 Corpus uteri
0.001 0.999 0.000
G56.4 Causalgia
0.000 0.999 0.001
N85.2 Hypertrophy of uterus
0.001 0.999 0.000
R76.0 Raised antibody titer
0.001 0.999 0.000
X78.0 Home
0.001 0.999 0.000
G56.1 Other lesions of median nerve
0.000 0.999 0.001
G57.1 Meralgia paraesthetica
0.000 0.999 0.001
I12.0 Hypertensive renal disease with renal failure
0.001 0.999 0.000
K12.3 Oral mucositis (ulcerative)
0.000 0.999 0.001
M51.8 Other specified intervertebral disk disorders
0.001 0.999 0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances
0.001 0.999 0.000
R82.1 Myoglobinuria
0.001 0.999 0.000
S62.51 Fracture of thumb (open)
0.000 0.999 0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.999 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.000 0.999 0.001
I46.9 Cardiac arrest, unspecified
0.001 0.999 0.000
M65.1 Other infective (teno)synovitis
0.001 0.999 0.000
N76.6 Ulceration of vulva
0.001 0.999 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.000 0.999 0.001
O69.4 Labour and delivery complicated by vasa praevia
0.000 0.999 0.001
O69.3 Labour and delivery complicated by short cord
0.000 0.999 0.001
Q43.0 Meckel's diverticulum
0.001 0.999 0.000
R82.8 Abnormal findings on cytological and histological examination of urine
0.001 0.999 0.000
S10.8 Superficial injury of other parts of neck
0.001 0.999 0.000
S11.2 Open wound involving pharynx and cervical oesophagus
0.001 0.999 0.000
S11.1 Open wound involving thyroid gland
0.001 0.999 0.000
S11.0 Open wound involving larynx and trachea
0.001 0.999 0.000
A02.0 Salmonella gastro-enteritis
0.000 0.999 0.001
C75.5 Aortic body and other paraganglia
0.001 0.999 0.000
F25.9 Schizoaffective disorder, unspecified
0.001 0.999 0.000
H65.0 Acute serous otitis media
0.001 0.999 0.000
Q39.6 Diverticulum of oesophagus
0.001 0.999 0.000
S09.8 Other specified injuries of head
0.001 0.999 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.000 0.999 0.001
Z57.3 Occupational exposure to other air contaminants
0.001 0.999 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.000 0.999 0.001
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.001 0.999 0.000
M65.19 Other infective (teno)synovitis (Site unspecified)
0.001 0.999 0.000
M65.18 Other infective (teno)synovitis (Other)
0.001 0.999 0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.001 0.999 0.000
M65.16 Other infective (teno)synovitis (Lower leg)
0.001 0.999 0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.001 0.999 0.000
M65.13 Other infective (teno)synovitis (Forearm)
0.001 0.999 0.000
M65.12 Other infective (teno)synovitis (Upper arm)
0.001 0.999 0.000
M65.11 Other infective (teno)synovitis (Shoulder region)
0.001 0.999 0.000
M65.10 Other infective (teno)synovitis (Multiple sites)
0.001 0.999 0.000
G11.9 Hereditary ataxia, unspecified
0.001 0.999 0.000
S11.8 Open wound of other parts of neck
0.001 0.999 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.000 0.999 0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.000 0.999 0.001
T91.3 Sequelae of injury of spinal cord
0.000 0.999 0.001
T92.1 Sequelae of fracture of arm
0.000 0.999 0.001
M10.90 Gout, unspecified (Multiple sites)
0.001 0.999 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.000 0.999 0.001
A41.0 Septicaemia due to Staphylococcus aureus
0.001 0.999 0.000
C02.1 Border of tongue
0.001 0.999 0.000
C75.9 Endocrine gland, unspecified
0.001 0.999 0.000
D48.4 Peritoneum
0.001 0.999 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.001 0.999 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.999 0.000
E28.3 Primary ovarian failure
0.000 0.999 0.001
Q43.1 Hirschsprung's disease
0.001 0.999 0.000
S49.7 Multiple injuries of shoulder and upper arm
0.000 0.999 0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.001 0.999 0.000
R87 Abnormal findings in specimens from female genital organs
0.001 0.999 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.000 0.999 0.001
M89.86 Other specified disorders of bone (Lower leg)
0.000 0.999 0.001
C10.9 Oropharynx, unspecified
0.000 0.999 0.001
D48.3 Retroperitoneum
0.001 0.999 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.001 0.999 0.000
H65.4 Other chronic nonsuppurative otitis media
0.000 0.999 0.001
L93.0 Discoid lupus erythematosus
0.000 0.999 0.001
M35.1 Other overlap syndromes
0.000 0.999 0.001
O72.2 Delayed and secondary postpartum haemorrhage
0.001 0.999 0.000
R87.8 Other abnormal findings
0.001 0.999 0.000
R87.5 Abnormal microbiological findings
0.001 0.999 0.000
R87.4 Abnormal immunological findings
0.001 0.999 0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.001 0.999 0.000
R87.1 Abnormal level of hormones
0.001 0.999 0.000
R87.0 Abnormal level of enzymes
0.001 0.999 0.000
U80.0 Penicillin resistant agent
0.001 0.999 0.000
Z57.2 Occupational exposure to dust
0.001 0.999 0.000
G50 Disorders of trigeminal nerve
0.000 0.999 0.001
D33.3 Cranial nerves
0.000 0.999 0.001
G50.8 Other disorders of trigeminal nerve
0.000 0.999 0.001
G57.5 Tarsal tunnel syndrome
0.000 0.999 0.001
H25.8 Other senile cataract
0.000 0.999 0.001
I72.8 Aneurysm of other specified arteries
0.000 0.999 0.001
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.000 0.999 0.001
T98 Sequelae of other and unspecified effects of external causes
0.001 0.999 0.000
M10.94 Gout, unspecified (Hand)
0.001 0.999 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.001 0.999 0.000
F25.0 Schizoaffective disorder, manic type
0.001 0.999 0.000
M43.8 Other specified deforming dorsopathies
0.001 0.999 0.000
T20.2 Burn of second degree of head and neck
0.000 0.999 0.001
T98.2 Sequelae of certain early complications of trauma
0.001 0.999 0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice
0.001 0.999 0.000
M43 Other deforming dorsopathies
0.001 0.999 0.000
T91 Sequelae of injuries of neck and trunk
0.000 0.999 0.001
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.000 0.999 0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.000 0.999 0.001
M43.29 Other fusion of spine (Site unspecified)
0.001 0.999 0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.27 Other fusion of spine (Lumbosacral region)
0.001 0.999 0.000
M43.26 Other fusion of spine (Lumbar region)
0.001 0.999 0.000
M43.25 Other fusion of spine (Thoracolumbar region)
0.001 0.999 0.000
M43.24 Other fusion of spine (Thoracic region)
0.001 0.999 0.000
M43.23 Other fusion of spine (Cervicothoracic region)
0.001 0.999 0.000
M43.22 Other fusion of spine (Cervical region)
0.001 0.999 0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)
0.001 0.999 0.000
M43.20 Other fusion of spine (Multiple sites in spine)
0.001 0.999 0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)
0.001 0.999 0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)
0.001 0.999 0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)
0.001 0.999 0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)
0.001 0.999 0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)
0.001 0.999 0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)
0.001 0.999 0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)
0.001 0.999 0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)
0.001 0.999 0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)
0.001 0.999 0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe
0.001 0.999 0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ
0.001 0.999 0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral
0.001 0.999 0.000
M43.46 Other recurrent atlantoaxial subluxation-Lumbar
0.001 0.999 0.000
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar
0.001 0.999 0.000
M43.44 Other recurrent atlantoaxial subluxation-Thoracic
0.001 0.999 0.000
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic
0.001 0.999 0.000
M43.42 Other recurrent atlantoaxial subluxation-Cervical
0.001 0.999 0.000
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl
0.001 0.999 0.000
M43.40 Other recurrent atlantoaxial subluxation-Mult site
0.001 0.999 0.000
M43.59 Other recurrent vertebral subluxation (Site unspecified)
0.001 0.999 0.000
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)
0.001 0.999 0.000
M43.56 Other recurrent vertebral subluxation (Lumbar region)
0.001 0.999 0.000
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)
0.001 0.999 0.000
M43.54 Other recurrent vertebral subluxation (Thoracic region)
0.001 0.999 0.000
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)
0.001 0.999 0.000
M43.52 Other recurrent vertebral subluxation (Cervical region)
0.001 0.999 0.000
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl
0.001 0.999 0.000
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)
0.001 0.999 0.000
M43.69 Torticollis-Site unspe
0.001 0.999 0.000
M43.68 Torticollis-Sacral/sacrococ
0.001 0.999 0.000
M43.67 Torticollis-Lumbosacral
0.001 0.999 0.000
M43.66 Torticollis-Lumbar
0.001 0.999 0.000
M43.65 Torticollis-Thoracolumbar
0.001 0.999 0.000
M43.64 Torticollis-Thoracic
0.001 0.999 0.000
M43.63 Torticollis-Cervicothoracic
0.001 0.999 0.000
M43.61 Torticollis-Occipit-atl-axl
0.001 0.999 0.000
M43.60 Torticollis-Mult site
0.001 0.999 0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)
0.001 0.999 0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)
0.001 0.999 0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)
0.001 0.999 0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)
0.001 0.999 0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)
0.001 0.999 0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)
0.001 0.999 0.000
M43.82 Other specified deforming dorsopathies (Cervical region)
0.001 0.999 0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)
0.001 0.999 0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)
0.001 0.999 0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)
0.001 0.999 0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)
0.001 0.999 0.000
M43.96 Deforming dorsopathy, unspecified (Lumbar region)
0.001 0.999 0.000
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)
0.001 0.999 0.000
M43.94 Deforming dorsopathy, unspecified (Thoracic region)
0.001 0.999 0.000
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)
0.001 0.999 0.000
M43.92 Deforming dorsopathy, unspecified (Cervical region)
0.001 0.999 0.000
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)
0.001 0.999 0.000
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)
0.001 0.999 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.001 0.999 0.000
S37.00 Injury of kidney (without open wound into cavity)
0.001 0.999 0.000
C75.8 Pluriglandular involvement, unspecified
0.001 0.999 0.000
C75.4 Carotid body
0.001 0.999 0.000
C75.3 Pineal gland
0.001 0.999 0.000
C75.2 Craniopharyngeal duct
0.001 0.999 0.000
C75.1 Pituitary gland
0.001 0.999 0.000
G54.0 Brachial plexus disorders
0.000 0.999 0.001
M43.9 Deforming dorsopathy, unspecified
0.001 0.999 0.000
M43.6 Torticollis
0.001 0.999 0.000
M43.5 Other recurrent vertebral subluxation
0.001 0.999 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.001 0.999 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.001 0.999 0.000
M43.2 Other fusion of spine
0.001 0.999 0.000
Q65.8 Other congenital deformities of hip
0.001 0.999 0.000
R83.9 Unspecified abnormal finding
0.001 0.999 0.000
R83.7 Abnormal histological findings
0.001 0.999 0.000
R83.6 Abnormal cytological findings
0.001 0.999 0.000
R83.5 Abnormal microbiological findings
0.001 0.999 0.000
R83.4 Abnormal immunological findings
0.001 0.999 0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances
0.001 0.999 0.000
R83.1 Abnormal level of hormones
0.001 0.999 0.000
R83.0 Abnormal level of enzymes
0.001 0.999 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.000 0.999 0.001
T91.4 Sequelae of injury of intrathoracic organs
0.000 0.999 0.001
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.000 0.999 0.001
U80.8 Agent resistant to other penicillin-related antibiotic
0.001 0.999 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.001 0.999 0.000
R83 Abnormal findings in cerebrospinal fluid
0.001 0.999 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.000 0.999 0.001
X78.99 Intentional self-harm by sharp object: Unspecified place: During unspecified activity
0.001 0.999 0.000
C74.0 Cortex of adrenal gland
0.001 0.999 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.001 0.999 0.000
F31.7 Bipolar affective disorder, currently in remission
0.001 0.999 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.000 0.999 0.001
J04.0 Acute laryngitis
0.001 0.999 0.000
X70.2 School, other institution and public administrative area
0.001 0.999 0.000
X78.9 Unspecified place
0.001 0.999 0.000
X78.8 Other specified place
0.001 0.999 0.000
X78.7 Farm
0.001 0.999 0.000
X78.6 Industrial and construction area
0.001 0.999 0.000
X78.5 Trade and service area
0.001 0.999 0.000
X78.4 Street and highway
0.001 0.999 0.000
X78.3 Sports and athletics area
0.001 0.999 0.000
X78.2 School, other institution and public administrative area
0.001 0.999 0.000
X78.1 Residential institution
0.001 0.999 0.000
X78 Intentional self-harm by sharp object
0.001 0.999 0.000
M43.62 Torticollis-Cervical
0.001 0.999 0.000
C74.1 Medulla of adrenal gland
0.001 0.999 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.000 0.999 0.001
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.999 0.001
N27.0 Small kidney, unilateral
0.001 0.999 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.001 0.999 0.000
R87.7 Abnormal histological findings
0.001 0.999 0.000
S49.8 Other specified injuries of shoulder and upper arm
0.000 0.999 0.001
T98.1 Sequelae of other and unspecified effects of external causes
0.001 0.999 0.000
W45.6 Industrial and construction area
0.001 0.999 0.000
X60.8 Other specified place
0.001 0.999 0.000
S92.30 Fracture of metatarsal bone (closed)
0.001 0.999 0.000
X60.09 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics; Home; During unspecified activity
0.001 0.999 0.000
X60.08 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, Home , While engaged in other specified activities
0.001 0.999 0.000
X60.99 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, Unspecified place, During unspecified activity
0.001 0.999 0.000
X70.89 Intentional self-harm by hanging, strangulation and suffocation : Other specified places : During unspecified activity
0.001 0.999 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.001 0.999 0.000
E88.2 Lipomatosis, not elsewhere classified
0.001 0.999 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.000 0.999 0.001
T90.4 Sequelae of injury of eye and orbit
0.001 0.999 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.001 0.999 0.000
C74 Malignant neoplasm of adrenal gland
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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