TreeWAS – Variant ID: rs12712127

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H25.0 Senile incipient cataract	0.000	0.973	0.027
H72 Perforation of tympanic membrane	0.000	0.975	0.025
H72.8 Other perforations of tympanic membrane	0.000	0.976	0.024
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.976	0.024
H66 Suppurative and unspecified otitis media	0.000	0.977	0.023
H65-H75 Diseases of middle ear and mastoid	0.000	0.977	0.023
I12.9 Hypertensive renal disease without renal failure	0.000	0.977	0.023
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.978	0.022
H72.2 Other marginal perforations of tympanic membrane	0.000	0.978	0.022
H69 Other disorders of Eustachian tube	0.000	0.980	0.020
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.980	0.020
H69.8 Other specified disorders of Eustachian tube	0.000	0.981	0.019
H66.4 Suppurative otitis media, unspecified	0.000	0.982	0.018
H65 Nonsuppurative otitis media	0.000	0.982	0.018
H66.0 Acute suppurative otitis media	0.000	0.982	0.018
H74 Other disorders of middle ear and mastoid	0.000	0.982	0.018
H72.0 Central perforation of tympanic membrane	0.000	0.982	0.018
H66.3 Other chronic suppurative otitis media	0.000	0.982	0.018
H70 Mastoiditis and related conditions	0.000	0.983	0.017
H72.1 Attic perforation of tympanic membrane	0.000	0.983	0.017
H71 Cholesteatoma of middle ear	0.000	0.983	0.017
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.983	0.017
H67 Otitis media in diseases classified elsewhere	0.000	0.983	0.017
H68 Eustachian salpingitis and obstruction	0.000	0.983	0.017
H74.0 Tympanosclerosis	0.000	0.983	0.017
H65.0 Acute serous otitis media	0.000	0.985	0.015
H65.1 Other acute nonsuppurative otitis media	0.000	0.985	0.015
H69.0 Patulous Eustachian tube	0.000	0.985	0.015
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.985	0.015
H65.2 Chronic serous otitis media	0.000	0.985	0.015
H70.9 Mastoiditis, unspecified	0.000	0.986	0.014
H65.4 Other chronic nonsuppurative otitis media	0.000	0.987	0.013
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.987	0.013
H69.9 Eustachian tube disorder, unspecified	0.000	0.987	0.013
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.987	0.013
H70.1 Chronic mastoiditis	0.000	0.987	0.013
H74.1 Adhesive middle ear disease	0.000	0.987	0.013
H70.8 Other mastoiditis and related conditions	0.000	0.987	0.013
H70.2 Petrositis	0.000	0.987	0.013
H74.4 Polyp of middle ear	0.000	0.987	0.013
H73 Other disorders of tympanic membrane	0.000	0.987	0.012
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.988	0.012
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.988	0.012
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.988	0.012
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.988	0.012
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.988	0.012
H68.0 Eustachian salpingitis	0.000	0.988	0.012
H68.1 Obstruction of Eustachian tube	0.000	0.988	0.012
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.989	0.011
H70.0 Acute mastoiditis	0.000	0.989	0.011
R53 Malaise and fatigue	0.011	0.989	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.990	0.010
H73.0 Acute myringitis	0.000	0.991	0.009
J92.0 Pleural plaque with presence of asbestos	0.009	0.991	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.992	0.008
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.008	0.992	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.992	0.008
H73.1 Chronic myringitis	0.000	0.992	0.008
H65.3 Chronic mucoid otitis media	0.000	0.993	0.007
H25 Senile cataract	0.000	0.993	0.007
H25.9 Senile cataract, unspecified	0.000	0.993	0.007
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.007	0.993	0.000
Q78.0 Osteogenesis imperfecta	0.007	0.993	0.000
S52.80 Fracture of other parts of forearm (closed)	0.007	0.993	0.000
Q78 Other osteochondrodysplasias	0.007	0.993	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.993	0.007
Q74 Other congenital malformations of limb(s)	0.007	0.993	0.000
Q66 Congenital deformities of feet	0.007	0.993	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.006	0.994	0.000
L03.1 Cellulitis of other parts of limb	0.006	0.994	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.006	0.994	0.000
Q66.7 Pes cavus	0.006	0.994	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.994	0.006
Q66.9 Congenital deformity of feet, unspecified	0.006	0.994	0.000
Q74.1 Congenital malformation of knee	0.006	0.994	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.994	0.006
Q79.0 Congenital diaphragmatic hernia	0.006	0.994	0.000
H66.9 Otitis media, unspecified	0.000	0.994	0.006
Q66.0 Talipes equinovarus	0.005	0.994	0.000
I12 Hypertensive renal disease	0.000	0.994	0.006
J92 Pleural plaque	0.006	0.994	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.005	0.995	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.995	0.005
Q79.6 Ehlers-Danlos syndrome	0.005	0.995	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.995	0.005
Q79.1 Other congenital malformations of diaphragm	0.005	0.995	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.995	0.005
C49.3 Connective and soft tissue of thorax	0.000	0.995	0.005
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
M43.02 Spondylolysis (Cervical region)	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q78.2 Osteopetrosis	0.005	0.995	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.005	0.995	0.000
Q78.8 Other specified osteochondrodysplasias	0.005	0.995	0.000
Q78.6 Multiple congenital exostoses	0.005	0.995	0.000
Q78.5 Metaphyseal dysplasia	0.005	0.995	0.000
Q78.4 Enchondromatosis	0.005	0.995	0.000
Q78.3 Progressive diaphyseal dysplasia	0.005	0.995	0.000
Q78.1 Polyostotic fibrous dysplasia	0.005	0.995	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.005	0.995	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.005	0.995	0.000
Q74.3 Arthrogryposis multiplex congenita	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
E11.5 With peripheral circulatory complications	0.005	0.995	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.995	0.005
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.005	0.995	0.000
Q79.5 Other congenital malformations of abdominal wall	0.005	0.995	0.000
Q79.4 Prune belly syndrome	0.005	0.995	0.000
Q79.3 Gastroschisis	0.005	0.995	0.000
Q79.2 Exomphalos	0.005	0.995	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.995	0.005
R01.1 Cardiac murmur, unspecified	0.005	0.995	0.000
R52.1 Chronic intractable pain	0.005	0.995	0.000
J86.9 Pyothorax without fistula	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.995	0.005
C49.9 Connective and soft tissue, unspecified	0.000	0.996	0.004
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
M43.0 Spondylolysis	0.004	0.996	0.000
C49.4 Connective and soft tissue of abdomen	0.000	0.996	0.004
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.004	0.996	0.000
M43.06 Spondylolysis (Lumbar region)	0.004	0.996	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.004	0.996	0.000
Q76.0 Spina bifida occulta	0.004	0.996	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.004	0.996	0.000
Q69.9 Polydactyly, unspecified	0.004	0.996	0.000
Q69.2 Accessory toe(s)	0.004	0.996	0.000
Q69.1 Accessory thumb(s)	0.004	0.996	0.000
Q69.0 Accessory finger(s)	0.004	0.996	0.000
Q70.9 Syndactyly, unspecified	0.004	0.996	0.000
Q70.4 Polysyndactyly	0.004	0.996	0.000
Q70.3 Webbed toes	0.004	0.996	0.000
Q70.2 Fused toes	0.004	0.996	0.000
Q70.1 Webbed fingers	0.004	0.996	0.000
Q70.0 Fused fingers	0.004	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.996	0.000
Q71.6 Lobster-claw hand	0.004	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.004	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.004	0.996	0.000
Q72.7 Split foot	0.004	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.004	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.004	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.004	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.004	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.004	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.004	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.004	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.004	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.004	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.004	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.004	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.004	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.004	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.004	0.996	0.000
Q75.3 Macrocephaly	0.004	0.996	0.000
Q75.2 Hypertelorism	0.004	0.996	0.000
Q75.1 Craniofacial dysostosis	0.004	0.996	0.000
Q75.0 Craniosynostosis	0.004	0.996	0.000
M43.09 Spondylolysis (Site unspecified)	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.996	0.000
Q68.3 Congenital bowing of femur	0.004	0.996	0.000
Q68.2 Congenital deformity of knee	0.004	0.996	0.000
Q68.1 Congenital deformity of hand	0.004	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.996	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
H25.8 Other senile cataract	0.000	0.996	0.004
S52.8 Fracture of other parts of forearm	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.003	0.996	0.000
Q65.6 Unstable hip	0.003	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.003	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.003	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.003	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.003	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.003	0.996	0.000
Q77.4 Achondroplasia	0.003	0.996	0.000
T51.9 Alcohol, unspecified	0.000	0.996	0.004
M62.8 Other specified disorders of muscle	0.004	0.996	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.003	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
E14.3 With ophthalmic complications	0.000	0.997	0.003
I27.0 Primary pulmonary hypertension	0.000	0.997	0.003
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.003	0.997	0.000
M43.04 Spondylolysis (Thoracic region)	0.003	0.997	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.003	0.997	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.003	0.997	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
R01.0 Benign and innocent cardiac murmurs	0.003	0.997	0.000
T51.0 Ethanol	0.000	0.997	0.003
M79.28 Neuralgia and neuritis, unspecified (Other)	0.003	0.997	0.000
D37.4 Colon	0.003	0.997	0.000
M79.2 Neuralgia and neuritis, unspecified	0.003	0.997	0.000
S52.81 Fracture of other parts of forearm (open)	0.003	0.997	0.000
R01 Cardiac murmurs and other cardiac sounds	0.003	0.997	0.000
M62.84 Other specified disorders of muscle (Hand)	0.003	0.997	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.003	0.997	0.000
T51 Toxic effect of alcohol	0.000	0.997	0.003
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.003	0.997	0.000
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
D37.5 Rectum	0.003	0.997	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.997	0.003
M62.88 Other specified disorders of muscle (Other)	0.003	0.997	0.000
D37.3 Appendix	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.997	0.003
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.003	0.997	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.003	0.997	0.000
H06.2 Dysthyroid exophthalmos	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.003	0.997	0.000
N62 Hypertrophy of breast	0.000	0.997	0.003
R45.0 Nervousness	0.000	0.997	0.003
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.003	0.997	0.000
I27 Other pulmonary heart diseases	0.000	0.997	0.003
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
J86 Pyothorax	0.003	0.997	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.002	0.997	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.002	0.997	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.002	0.997	0.000
D37.9 Digestive organ, unspecified	0.002	0.997	0.000
D37.6 Liver, gallbladder and bile ducts	0.002	0.997	0.000
R01.2 Other cardiac sounds	0.002	0.997	0.000
T51.8 Other alcohols	0.000	0.998	0.002
T51.3 Fusel oil	0.000	0.998	0.002
T51.2 2-Propanol	0.000	0.998	0.002
T51.1 Methanol	0.000	0.998	0.002
D37.2 Small intestine	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
R45.1 Restlessness and agitation	0.000	0.998	0.002
D37.1 Stomach	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
R45 Symptoms and signs involving emotional state	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.000	0.998	0.002
R45.6 Physical violence	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
M76.66 Achilles tendinitis (Lower leg)	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.998	0.002
O26.9 Pregnancy-related condition, unspecified	0.002	0.998	0.000
R45.5 Hostility	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
R45.4 Irritability and anger	0.000	0.998	0.002
M62.4 Contracture of muscle	0.002	0.998	0.000
Z49.2 Other dialysis	0.000	0.998	0.002
C10.9 Oropharynx, unspecified	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
R45.3 Demoralisation and apathy	0.000	0.998	0.002
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S54.0 Injury of ulnar nerve at forearm level	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
F45.3 Somatoform autonomic dysfunction	0.000	0.998	0.002
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
C32.0 Glottis	0.000	0.998	0.002
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
M62.46 Contracture of muscle (Lower leg)	0.002	0.998	0.000
C67.1 Dome of bladder	0.000	0.998	0.002
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
N61 Inflammatory disorders of breast	0.000	0.998	0.002
Q05 Spina bifida	0.002	0.998	0.000
J86.0 Pyothorax with fistula	0.002	0.998	0.000
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
M62.08 Diastasis of muscle (Other)	0.002	0.998	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.000	0.998	0.002
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.002	0.998	0.000
J18.1 Lobar pneumonia, unspecified	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.002	0.998	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C46 Kaposi's sarcoma	0.000	0.998	0.002
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.002
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
B99 Other and unspecified infectious diseases	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.000	0.998	0.002
R45.2 Unhappiness	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
M62.49 Contracture of muscle (Site unspecified)	0.002	0.998	0.000
M62.48 Contracture of muscle (Other)	0.002	0.998	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.002	0.998	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M62.44 Contracture of muscle (Hand)	0.002	0.998	0.000
M62.43 Contracture of muscle (Forearm)	0.002	0.998	0.000
M62.42 Contracture of muscle (Upper arm)	0.002	0.998	0.000
M62.41 Contracture of muscle (Shoulder region)	0.002	0.998	0.000
M62.40 Contracture of muscle (Multiple sites)	0.002	0.998	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.002	0.998	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.002	0.998	0.000
M62.06 Diastasis of muscle (Lower leg)	0.002	0.998	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M62.04 Diastasis of muscle (Hand)	0.002	0.998	0.000
M62.03 Diastasis of muscle (Forearm)	0.002	0.998	0.000
M62.02 Diastasis of muscle (Upper arm)	0.002	0.998	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.002	0.998	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.000	0.998	0.002
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.002	0.998	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.002	0.998	0.000
S68.4 Traumatic amputation of hand at wrist level	0.002	0.998	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.002	0.998	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.998	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.998	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.998	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.998	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.998	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.998	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.998	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.998	0.000
R77.1 Abnormality of globulin	0.000	0.998	0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
O41.0 Oligohydramnios	0.000	0.998	0.002
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.998	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.998	0.002
W50.9 Unspecified place	0.002	0.998	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.998	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.998	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.998	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.998	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.998	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.998	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.998	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.998	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.998	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.998	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.002	0.998	0.000
M62.6 Muscle strain	0.001	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.998	0.001
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.998	0.001
C46.7 Kaposi's sarcoma of other sites	0.000	0.998	0.001
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.998	0.001
C46.2 Kaposi's sarcoma of palate	0.000	0.998	0.001
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.998	0.001
C46.0 Kaposi's sarcoma of skin	0.000	0.998	0.001
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.998	0.001
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.998	0.001
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.998	0.001
C47.5 Peripheral nerves of pelvis	0.000	0.998	0.001
C47.4 Peripheral nerves of abdomen	0.000	0.998	0.001
C47.3 Peripheral nerves of thorax	0.000	0.998	0.001
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.998	0.001
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.998	0.001
C47.0 Peripheral nerves of head, face and neck	0.000	0.998	0.001
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
N20.9 Urinary calculus, unspecified	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.998	0.000
S54 Injury of nerves at forearm level	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.998	0.000
C32.9 Larynx, unspecified	0.000	0.998	0.002
D37.7 Other digestive organs	0.001	0.998	0.000
S54.1 Injury of median nerve at forearm level	0.001	0.998	0.000
T31.0 Burns involving less than 10% of body surface	0.002	0.998	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.998	0.001
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
L21.9 Seborrhoeic dermatitis, unspecified	0.002	0.998	0.000
M76.6 Achilles tendinitis	0.002	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.001	0.998	0.000
Q04.5 Megalencephaly	0.001	0.998	0.000
Q04.4 Septo-optic dysplasia	0.001	0.998	0.000
Q04.3 Other reduction deformities of brain	0.001	0.998	0.000
Q04.2 Holoprosencephaly	0.001	0.998	0.000
Q04.1 Arhinencephaly	0.001	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.001	0.998	0.000
Z49.0 Preparatory care for dialysis	0.000	0.998	0.002
Q61 Cystic kidney disease	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.001	0.998	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.001	0.998	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.001	0.998	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.001	0.998	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.001	0.998	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.001	0.998	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.001	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.998	0.000
C48.0 Retroperitoneum	0.000	0.998	0.001
R85.7 Abnormal histological findings	0.001	0.998	0.000
R89.7 Abnormal histological findings	0.001	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.001	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.001
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.998	0.000
C32.1 Supraglottis	0.000	0.998	0.001
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.001	0.998	0.000
Q01 Encephalocele	0.001	0.998	0.000
Q00 Anencephaly and similar malformations	0.001	0.998	0.000
Q02 Microcephaly	0.001	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
Q04.8 Other specified congenital malformations of brain	0.001	0.998	0.000
C32 Malignant neoplasm of larynx	0.000	0.998	0.001
T58 Toxic effect of carbon monoxide	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations