TreeWAS – Variant ID: rs12713956

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.122	0.878
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.668	0.332
E78.2 Mixed hyperlipidaemia	0.000	0.689	0.311
E78.6 Lipoprotein deficiency	0.000	0.762	0.238
E78.4 Other hyperlipidaemia	0.000	0.762	0.238
E78.3 Hyperchylomicronaemia	0.000	0.762	0.238
E78.8 Other disorders of lipoprotein metabolism	0.000	0.776	0.224
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.792	0.208
E78.1 Pure hyperglyceridaemia	0.000	0.832	0.167
E78.5 Hyperlipidaemia, unspecified	0.000	0.880	0.120
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.938	0.062
Z80.3 Family history of malignant neoplasm of breast	0.000	0.940	0.060
I25 Chronic ischaemic heart disease	0.000	0.940	0.060
I25.1 Atherosclerotic heart disease	0.000	0.943	0.057
I25.5 Ischaemic cardiomyopathy	0.000	0.945	0.055
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.948	0.052
E70-E90 Metabolic disorders	0.000	0.950	0.050
I25.3 Aneurysm of heart	0.000	0.951	0.048
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.954	0.046
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.956	0.044
I25.6 Silent myocardial ischaemia	0.000	0.957	0.043
A04.8 Other specified bacterial intestinal infections	0.000	0.957	0.043
E87.6 Hypokalaemia	0.000	0.959	0.041
E85 Amyloidosis	0.000	0.959	0.041
E87.5 Hyperkalaemia	0.000	0.959	0.041
I25.4 Coronary artery aneurysm	0.000	0.961	0.039
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.963	0.037
E84 Cystic fibrosis	0.000	0.964	0.036
E79 Disorders of purine and pyrimidine metabolism	0.000	0.964	0.036
E77 Disorders of glycoprotein metabolism	0.000	0.964	0.036
E76 Disorders of glycosaminoglycan metabolism	0.000	0.964	0.036
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.964	0.036
E72 Other disorders of amino-acid metabolism	0.000	0.964	0.036
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.964	0.036
E70 Disorders of aromatic amino-acid metabolism	0.000	0.964	0.036
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.964	0.036
E83 Disorders of mineral metabolism	0.000	0.965	0.035
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.965	0.035
E74 Other disorders of carbohydrate metabolism	0.000	0.966	0.034
I25.2 Old myocardial infarction	0.000	0.967	0.033
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.967	0.033
E85.4 Organ-limited amyloidosis	0.000	0.967	0.033
E73 Lactose intolerance	0.000	0.968	0.032
E85.9 Amyloidosis, unspecified	0.000	0.968	0.032
E87.4 Mixed disorder of acid-base balance	0.000	0.968	0.032
E89.2 Postprocedural hypoparathyroidism	0.000	0.969	0.031
E88 Other metabolic disorders	0.000	0.969	0.031
E85.8 Other amyloidosis	0.000	0.970	0.030
E85.3 Secondary systemic amyloidosis	0.000	0.970	0.030
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.970	0.030
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.970	0.030
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.970	0.030
E83.3 Disorders of phosphorus metabolism	0.000	0.971	0.029
E87.3 Alkalosis	0.000	0.972	0.028
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.974	0.026
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.974	0.026
E70.3 Albinism	0.000	0.974	0.026
E70.2 Disorders of tyrosine metabolism	0.000	0.974	0.026
E70.1 Other hyperphenylalaninaemias	0.000	0.974	0.026
E70.0 Classical phenylketonuria	0.000	0.974	0.026
E71.3 Disorders of fatty-acid metabolism	0.000	0.974	0.026
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.974	0.026
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.974	0.026
E71.0 Maple-syrup-urine disease	0.000	0.974	0.026
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.974	0.026
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.974	0.026
E72.5 Disorders of glycine metabolism	0.000	0.974	0.026
E72.4 Disorders of ornithine metabolism	0.000	0.974	0.026
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.974	0.026
E72.2 Disorders of urea cycle metabolism	0.000	0.974	0.026
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.974	0.026
E72.0 Disorders of amino-acid transport	0.000	0.974	0.026
E75.6 Lipid storage disorder, unspecified	0.000	0.974	0.026
E75.5 Other lipid storage disorders	0.000	0.974	0.026
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.974	0.026
E75.3 Sphingolipidosis, unspecified	0.000	0.974	0.026
E75.2 Other sphingolipidosis	0.000	0.974	0.026
E75.1 Other gangliosidosis	0.000	0.974	0.026
E75.0 GM2 gangliosidosis	0.000	0.974	0.026
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.974	0.026
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.974	0.026
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.974	0.026
E76.2 Other mucopolysaccharidoses	0.000	0.974	0.026
E76.1 Mucopolysaccharidosis, type II	0.000	0.974	0.026
E76.0 Mucopolysaccharidosis, type I	0.000	0.974	0.026
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.974	0.026
E77.8 Other disorders of glycoprotein metabolism	0.000	0.974	0.026
E77.1 Defects in glycoprotein degradation	0.000	0.974	0.026
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.974	0.026
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.974	0.026
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.974	0.026
E79.1 Lesch-Nyhan syndrome	0.000	0.974	0.026
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.974	0.026
E84.9 Cystic fibrosis, unspecified	0.000	0.974	0.026
E84.8 Cystic fibrosis with other manifestations	0.000	0.974	0.026
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.974	0.026
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.974	0.026
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.974	0.026
E83.8 Other disorders of mineral metabolism	0.000	0.974	0.026
E83.2 Disorders of zinc metabolism	0.000	0.974	0.026
E83.0 Disorders of copper metabolism	0.000	0.974	0.026
E83.1 Disorders of iron metabolism	0.000	0.974	0.025
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.975	0.025
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.975	0.025
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.975	0.025
E89.5 Postprocedural testicular hypofunction	0.000	0.975	0.025
E89.4 Postprocedural ovarian failure	0.000	0.975	0.025
E89.1 Postprocedural hypoinsulinaemia	0.000	0.975	0.025
A04 Other bacterial intestinal infections	0.000	0.975	0.025
E80 Disorders of porphyrin and bilirubin metabolism	0.001	0.975	0.024
E87.0 Hyperosmolality and hypernatraemia	0.000	0.975	0.025
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.975	0.024
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.975	0.024
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.975	0.024
E74.2 Disorders of galactose metabolism	0.000	0.975	0.024
E74.1 Disorders of fructose metabolism	0.000	0.975	0.024
E74.0 Glycogen storage disease	0.000	0.975	0.024
E89.3 Postprocedural hypopituitarism	0.000	0.976	0.024
E83.5 Disorders of calcium metabolism	0.000	0.976	0.024
E73.8 Other lactose intolerance	0.000	0.977	0.023
E73.1 Secondary lactase deficiency	0.000	0.977	0.023
E73.0 Congenital lactase deficiency	0.000	0.977	0.023
E87.7 Fluid overload	0.000	0.977	0.023
E83.4 Disorders of magnesium metabolism	0.000	0.978	0.022
E88.9 Metabolic disorder, unspecified	0.000	0.978	0.022
E88.8 Other specified metabolic disorders	0.000	0.978	0.022
E88.3 Tumour lysis syndrome	0.000	0.978	0.022
E88.2 Lipomatosis, not elsewhere classified	0.000	0.978	0.022
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.978	0.022
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.978	0.022
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.979	0.021
E73.9 Lactose intolerance, unspecified	0.000	0.981	0.019
A04.9 Bacterial intestinal infection, unspecified	0.000	0.982	0.018
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.982	0.018
A04.4 Other intestinal Escherichia coli infections	0.000	0.982	0.018
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.982	0.018
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.982	0.018
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.982	0.018
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.982	0.018
E80.7 Disorder of bilirubin metabolism, unspecified	0.001	0.982	0.018
E80.6 Other disorders of bilirubin metabolism	0.001	0.982	0.018
E80.5 Crigler-Najjar syndrome	0.001	0.982	0.018
E80.3 Defects of catalase and peroxydase	0.001	0.982	0.018
E80.2 Other porphyria	0.001	0.982	0.018
E80.1 Porphyria cutanea tarda	0.001	0.982	0.018
E80.0 Hereditary erythropoietic porphyria	0.001	0.982	0.018
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.983	0.016
A04.5 Campylobacter enteritis	0.000	0.985	0.015
H02.8 Other specified disorders of eyelid	0.000	0.986	0.014
I20-I25 Ischaemic heart diseases	0.000	0.989	0.011
I22 Subsequent myocardial infarction	0.000	0.989	0.011
E87.2 Acidosis	0.000	0.989	0.011
A00-A09 Intestinal infectious diseases	0.000	0.989	0.011
F31 Bipolar affective disorder	0.010	0.990	0.000
O63.1 Prolonged second stage (of labour)	0.010	0.990	0.000
E86 Volume depletion	0.000	0.990	0.010
F31.0 Bipolar affective disorder, current episode hypomanic	0.010	0.990	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.990	0.010
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.990	0.010
A08 Viral and other specified intestinal infections	0.000	0.990	0.009
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.009	0.991	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.009	0.991	0.000
M35.3 Polymyalgia rheumatica	0.000	0.991	0.009
I22.8 Subsequent myocardial infarction of other sites	0.000	0.991	0.009
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.009	0.991	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.009	0.991	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.008	0.992	0.000
A02 Other Salmonella infections	0.000	0.992	0.008
E89.0 Postprocedural hypothyroidism	0.000	0.992	0.008
A08.4 Viral intestinal infection, unspecified	0.000	0.992	0.008
F31.7 Bipolar affective disorder, currently in remission	0.008	0.992	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.992	0.008
F31.9 Bipolar affective disorder, unspecified	0.008	0.992	0.000
A06 Amoebiasis	0.000	0.992	0.008
A05 Other bacterial foodborne intoxications	0.000	0.992	0.008
A03 Shigellosis	0.000	0.992	0.008
A01 Typhoid and paratyphoid fevers	0.000	0.992	0.008
A00 Cholera	0.000	0.992	0.008
F31.6 Bipolar affective disorder, current episode mixed	0.008	0.992	0.000
I24 Other acute ischaemic heart diseases	0.000	0.992	0.008
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.992	0.008
F31.8 Other bipolar affective disorders	0.008	0.992	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.992	0.007
Z80 Family history of malignant neoplasm	0.000	0.992	0.008
A08.5 Other specified intestinal infections	0.000	0.993	0.007
A08.3 Other viral enteritis	0.000	0.993	0.007
A08.2 Adenoviral enteritis	0.000	0.993	0.007
A08.0 Rotaviral enteritis	0.000	0.993	0.007
I24.8 Other forms of acute ischaemic heart disease	0.000	0.993	0.007
A07 Other protozoal intestinal diseases	0.000	0.993	0.007
E80.4 Gilbert's syndrome	0.001	0.993	0.005
A02.0 Salmonella gastro-enteritis	0.000	0.993	0.007
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.993	0.007
A02.9 Salmonella infection, unspecified	0.000	0.994	0.006
A02.8 Other specified Salmonella infections	0.000	0.994	0.006
A02.2 Localised Salmonella infections	0.000	0.994	0.006
A02.1 Salmonella septicaemia	0.000	0.994	0.006
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.994	0.006
A00.9 Cholera, unspecified	0.000	0.994	0.006
A00.1 Cholera due to Vibrio cholerae 01, biovar el tor	0.000	0.994	0.006
A00.0 Cholera due to Vibrio cholerae 01, biovar cholerae	0.000	0.994	0.006
A01.4 Paratyphoid fever, unspecified	0.000	0.994	0.006
A01.3 Paratyphoid fever C	0.000	0.994	0.006
A01.2 Paratyphoid fever B	0.000	0.994	0.006
A01.1 Paratyphoid fever A	0.000	0.994	0.006
A01.0 Typhoid fever	0.000	0.994	0.006
A03.9 Shigellosis, unspecified	0.000	0.994	0.006
A03.8 Other shigellosis	0.000	0.994	0.006
A03.3 Shigellosis due to Shigella sonnei	0.000	0.994	0.006
A03.2 Shigellosis due to Shigella boydii	0.000	0.994	0.006
A03.1 Shigellosis due to Shigella flexneri	0.000	0.994	0.006
A03.0 Shigellosis due to Shigella dysenteriae	0.000	0.994	0.006
A05.9 Bacterial foodborne intoxication, unspecified	0.000	0.994	0.006
A05.8 Other specified bacterial foodborne intoxications	0.000	0.994	0.006
A05.4 Foodborne Bacillus cereus intoxication	0.000	0.994	0.006
A05.3 Foodborne Vibrio parahaemolyticus intoxication	0.000	0.994	0.006
A05.2 Foodborne Clostridium perfringens [Clostridium welchii] intoxication	0.000	0.994	0.006
A05.1 Botulism	0.000	0.994	0.006
A05.0 Foodborne staphylococcal intoxication	0.000	0.994	0.006
A06.9 Amoebiasis, unspecified	0.000	0.994	0.006
A06.8 Amoebic infection of other sites	0.000	0.994	0.006
A06.7 Cutaneous amoebiasis	0.000	0.994	0.006
A06.6 Amoebic brain abscess	0.000	0.994	0.006
A06.5 Amoebic lung abscess	0.000	0.994	0.006
A06.4 Amoebic liver abscess	0.000	0.994	0.006
A06.3 Amoeboma of intestine	0.000	0.994	0.006
A06.2 Amoebic nondysenteric colitis	0.000	0.994	0.006
A06.1 Chronic intestinal amoebiasis	0.000	0.994	0.006
A06.0 Acute amoebic dysentery	0.000	0.994	0.006
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.994	0.006
T51.0 Ethanol	0.000	0.994	0.006
I24.1 Dressler's syndrome	0.000	0.994	0.006
O63 Long labour	0.006	0.994	0.000
O62.3 Precipitate labour	0.006	0.994	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.994	0.005
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.994	0.005
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.994	0.005
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.994	0.005
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.994	0.005
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.994	0.005
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.994	0.005
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.994	0.006
O62 Abnormalities of forces of labour	0.006	0.994	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.994	0.006
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.994	0.005
L60.0 Ingrowing nail	0.005	0.995	0.000
O60-O75 Complications of labour and delivery	0.005	0.995	0.000
Z80.6 Family history of leukaemia	0.000	0.995	0.005
A07.9 Protozoal intestinal disease, unspecified	0.000	0.995	0.005
A07.8 Other specified protozoal intestinal diseases	0.000	0.995	0.005
A07.3 Isosporiasis	0.000	0.995	0.005
A07.2 Cryptosporidiosis	0.000	0.995	0.005
A07.0 Balantidiasis	0.000	0.995	0.005
J98.4 Other disorders of lung	0.000	0.995	0.005
L60 Nail disorders	0.005	0.995	0.000
O62.2 Other uterine inertia	0.005	0.995	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.995	0.005
L60.8 Other nail disorders	0.005	0.995	0.000
L72.0 Epidermal cyst	0.005	0.995	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.000	0.995	0.005
O66 Other obstructed labour	0.005	0.995	0.000
O61 Failed induction of labour	0.005	0.995	0.000
O62.0 Primary inadequate contractions	0.004	0.995	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.995	0.004
L60.3 Nail dystrophy	0.004	0.995	0.000
O72 Postpartum haemorrhage	0.004	0.996	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.004	0.996	0.000
O62.9 Abnormality of forces of labour, unspecified	0.004	0.996	0.000
O62.8 Other abnormalities of forces of labour	0.004	0.996	0.000
O62.1 Secondary uterine inertia	0.004	0.996	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
L60.2 Onychogryphosis	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.996	0.000
A07.1 Giardiasis [lambliasis]	0.000	0.996	0.004
O66.0 Obstructed labour due to shoulder dystocia	0.004	0.996	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.004	0.996	0.000
O74 Complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.004	0.996	0.000
O60 Preterm delivery	0.004	0.996	0.000
H40.1 Primary open-angle glaucoma	0.000	0.996	0.004
O61.1 Failed instrumental induction of labour	0.004	0.996	0.000
L60.5 Yellow nail syndrome	0.004	0.996	0.000
L60.4 Beau's lines	0.004	0.996	0.000
L60.1 Onycholysis	0.004	0.996	0.000
L60.9 Nail disorder, unspecified	0.004	0.996	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.004	0.996	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.004	0.996	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.004	0.996	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.004	0.996	0.000
O61.0 Failed medical induction of labour	0.004	0.996	0.000
O72.1 Other immediate postpartum haemorrhage	0.004	0.996	0.000
O90 Complications of the puerperium, not elsewhere classified	0.004	0.996	0.000
O85-O92 Complications predominantly related to the puerperium	0.004	0.996	0.000
T51 Toxic effect of alcohol	0.000	0.996	0.004
O03.4 Incomplete, without complication	0.004	0.996	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.004	0.996	0.000
O66.9 Obstructed labour, unspecified	0.003	0.996	0.000
O66.8 Other specified obstructed labour	0.003	0.996	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.003	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.003	0.996	0.000
O66.1 Obstructed labour due to locked twins	0.003	0.996	0.000
O86 Other puerperal infections	0.004	0.996	0.000
L71.9 Rosacea, unspecified	0.004	0.996	0.000
O61.9 Failed induction of labour, unspecified	0.003	0.996	0.000
O61.8 Other failed induction of labour	0.003	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.004	0.996	0.000
F40.2 Specific (isolated) phobias	0.004	0.996	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.996	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.003	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.004	0.996	0.000
O86.4 Pyrexia of unknown origin following delivery	0.003	0.996	0.000
O90.1 Disruption of perineal obstetric wound	0.003	0.996	0.000
O73 Retained placenta and membranes, without haemorrhage	0.003	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.003	0.996	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.996	0.003
O72.3 Postpartum coagulation defects	0.003	0.997	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O67.8 Other intrapartum haemorrhage	0.003	0.997	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.003	0.997	0.000
O71 Other obstetric trauma	0.003	0.997	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.997	0.003
O00-O08 Pregnancy with abortive outcome	0.003	0.997	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.997	0.003
O72.0 Third-stage haemorrhage	0.003	0.997	0.000
L71 Rosacea	0.003	0.997	0.000
O75.8 Other specified complications of labour and delivery	0.003	0.997	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.003	0.997	0.000
O03 Spontaneous abortion	0.003	0.997	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.001	0.997	0.003
T51.9 Alcohol, unspecified	0.000	0.997	0.003
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.003	0.997	0.000
O60.3 Preterm delivery without spontaneous labour	0.003	0.997	0.000
O60.2 Preterm spontaneous labour with term delivery	0.003	0.997	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.003	0.997	0.000
O60.0 Preterm labour without delivery	0.003	0.997	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.003	0.997	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.003	0.997	0.000
O64.5 Obstructed labour due to compound presentation	0.003	0.997	0.000
O64.4 Obstructed labour due to shoulder presentation	0.003	0.997	0.000
O64.3 Obstructed labour due to brow presentation	0.003	0.997	0.000
O64.2 Obstructed labour due to face presentation	0.003	0.997	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.003	0.997	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.003	0.997	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.003	0.997	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.003	0.997	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.003	0.997	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.003	0.997	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.003	0.997	0.000
O65.0 Obstructed labour due to deformed pelvis	0.003	0.997	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.003	0.997	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.003	0.997	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.003	0.997	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.003	0.997	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.003	0.997	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.003	0.997	0.000
D64.9 Anaemia, unspecified	0.000	0.997	0.003
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.3 Other infection during labour	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.997	0.003
O02 Other abnormal products of conception	0.003	0.997	0.000
O85 Puerperal sepsis	0.003	0.997	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.003	0.997	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.003	0.997	0.000
O69.3 Labour and delivery complicated by short cord	0.003	0.997	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.003	0.997	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.000	0.997	0.003
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.997	0.003
O90.9 Complication of the puerperium, unspecified	0.003	0.997	0.000
O90.5 Postpartum thyroiditis	0.003	0.997	0.000
O90.4 Postpartum acute renal failure	0.003	0.997	0.000
O90.3 Cardiomyopathy in the puerperium	0.003	0.997	0.000
O90.2 Haematoma of obstetric wound	0.003	0.997	0.000
O90.0 Disruption of Caesarean section wound	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.003	0.997	0.000
O91 Infections of breast associated with childbirth	0.003	0.997	0.000
O89 Complications of anaesthesia during the puerperium	0.003	0.997	0.000
O88 Obstetric embolism	0.003	0.997	0.000
T51.8 Other alcohols	0.000	0.997	0.003
T51.3 Fusel oil	0.000	0.997	0.003
T51.2 2-Propanol	0.000	0.997	0.003
T51.1 Methanol	0.000	0.997	0.003
O08 Complications following abortion and ectopic and molar pregnancy	0.003	0.997	0.000
O87 Venous complications in the puerperium	0.003	0.997	0.000
L60-L75 Disorders of skin appendages	0.003	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.003	0.997	0.000
O86.0 Infection of obstetric surgical wound	0.003	0.997	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.003	0.997	0.000
O86.8 Other specified puerperal infections	0.003	0.997	0.000
O86.3 Other genito-urinary tract infections following delivery	0.003	0.997	0.000
O86.2 Urinary tract infection following delivery	0.003	0.997	0.000
O86.1 Other infection of genital tract following delivery	0.003	0.997	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
O23 Infections of genito-urinary tract in pregnancy	0.003	0.997	0.000
O24 Diabetes mellitus in pregnancy	0.003	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.003	0.997	0.000
L71.1 Rhinophyma	0.003	0.997	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.003	0.997	0.000
O22 Venous complications in pregnancy	0.003	0.997	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.997	0.003
Z95.4 Presence of other heart-valve replacement	0.000	0.997	0.003
O00 Ectopic pregnancy	0.003	0.997	0.000
K62.3 Rectal prolapse	0.003	0.997	0.000
H53.4 Visual field defects	0.000	0.997	0.003
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.003	0.997	0.000
O71.9 Obstetric trauma, unspecified	0.002	0.997	0.000
O71.7 Obstetric haematoma of pelvis	0.002	0.997	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.002	0.997	0.000
O71.5 Other obstetric injury to pelvic organs	0.002	0.997	0.000
O71.3 Obstetric laceration of cervix	0.002	0.997	0.000
O71.2 Postpartum inversion of uterus	0.002	0.997	0.000
O71.1 Rupture of uterus during labour	0.002	0.997	0.000
O71.0 Rupture of uterus before onset of labour	0.002	0.997	0.000
O07 Failed attempted abortion	0.003	0.997	0.000
O06 Unspecified abortion	0.003	0.997	0.000
O05 Other abortion	0.003	0.997	0.000
O01 Hydatidiform mole	0.003	0.997	0.000
B18 Chronic viral hepatitis	0.000	0.997	0.003
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
O64.1 Obstructed labour due to breech presentation	0.002	0.997	0.000
L71.8 Other rosacea	0.003	0.997	0.000
L71.0 Perioral dermatitis	0.003	0.997	0.000
O20.8 Other haemorrhage in early pregnancy	0.003	0.997	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.000	0.997	0.003
O75.0 Maternal distress during labour and delivery	0.002	0.997	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.997	0.003
O63.9 Long labour, unspecified	0.002	0.997	0.001
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.997	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.002	0.997	0.000
O03.7 Complete or unspecified, complicated by embolism	0.002	0.997	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.997	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.997	0.000
O03.3 Incomplete, with other and unspecified complications	0.002	0.997	0.000
O03.2 Incomplete, complicated by embolism	0.002	0.997	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.997	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.997	0.000
O25 Malnutrition in pregnancy	0.002	0.997	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.997	0.000
O44.1 Placenta praevia with haemorrhage	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.997	0.000
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
F52.2 Failure of genital response	0.003	0.997	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.003	0.997	0.000
O44 Placenta praevia	0.003	0.997	0.000
O71.8 Other specified obstetric trauma	0.002	0.997	0.000
O02.1 Missed abortion	0.003	0.997	0.000
O22.4 Haemorrhoids in pregnancy	0.002	0.997	0.000
O69.8 Labour and delivery complicated by other cord complications	0.002	0.997	0.000
O21 Excessive vomiting in pregnancy	0.002	0.997	0.000
O02.9 Abnormal product of conception, unspecified	0.002	0.997	0.000
O02.8 Other specified abnormal products of conception	0.002	0.997	0.000
F40 Phobic anxiety disorders	0.002	0.997	0.000
O00.9 Ectopic pregnancy, unspecified	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
O88.8 Other obstetric embolism	0.002	0.998	0.000
O88.3 Obstetric pyaemic and septic embolism	0.002	0.998	0.000
O88.2 Obstetric blood-clot embolism	0.002	0.998	0.000
O88.1 Amniotic fluid embolism	0.002	0.998	0.000
O88.0 Obstetric air embolism	0.002	0.998	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.002	0.998	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.6 Failed or difficult intubation during the puerperium	0.002	0.998	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.002	0.998	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.002	0.998	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.002	0.998	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.002	0.998	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.002	0.998	0.000
O91.1 Abscess of breast associated with childbirth	0.002	0.998	0.000
O91.0 Infection of nipple associated with childbirth	0.002	0.998	0.000
O92.7 Other and unspecified disorders of lactation	0.002	0.998	0.000
O92.6 Galactorrhoea	0.002	0.998	0.000
O92.5 Suppressed lactation	0.002	0.998	0.000
O92.4 Hypogalactia	0.002	0.998	0.000
O92.3 Agalactia	0.002	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.002	0.998	0.000
O92.1 Cracked nipple associated with childbirth	0.002	0.998	0.000
O92.0 Retracted nipple associated with childbirth	0.002	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.998	0.002
L70 Acne	0.002	0.998	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.998	0.002
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.002	0.998	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations