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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12722495
log Bayes Factor = 2.89266
Chromosome 10   position 6,097,283  (GRCh37) Explore rs12722495 on Ensembl!
Variant rs12722495 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.003 0.997
E10.9 Without complications
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.017 0.983
E10.5 With peripheral circulatory complications
0.000 0.155 0.845
E10.4 With neurological complications
0.000 0.169 0.831
E10.2 With renal complications
0.000 0.194 0.806
E10.6 With other specified complications
0.000 0.259 0.741
E10.8 With unspecified complications
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.285 0.715
E10-E14 Diabetes mellitus
0.000 0.316 0.684
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.365 0.635
E00-E07 Disorders of thyroid gland
0.000 0.368 0.632
E03 Other hypothyroidism
0.000 0.379 0.621
E20-E35 Disorders of other endocrine glands
0.000 0.383 0.617
E03.9 Hypothyroidism, unspecified
0.000 0.392 0.608
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.420 0.580
E10.0 With coma
0.000 0.444 0.556
E28 Ovarian dysfunction
0.000 0.468 0.532
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.479 0.521
E22 Hyperfunction of pituitary gland
0.000 0.480 0.520
E24 Cushing's syndrome
0.000 0.481 0.519
E03.8 Other specified hypothyroidism
0.000 0.492 0.508
E26 Hyperaldosteronism
0.000 0.493 0.507
E27 Other disorders of adrenal gland
0.000 0.494 0.506
E06 Thyroiditis
0.000 0.498 0.502
E12 Malnutrition-related diabetes mellitus
0.000 0.509 0.490
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.518 0.482
E13 Other specified diabetes mellitus
0.000 0.519 0.481
E40-E46 Malnutrition
0.000 0.521 0.479
E23 Hypofunction and other disorders of pituitary gland
0.000 0.532 0.468
E24.9 Cushing's syndrome, unspecified
0.000 0.542 0.458
E22.0 Acromegaly and pituitary gigantism
0.000 0.544 0.456
E28.2 Polycystic ovarian syndrome
0.000 0.545 0.455
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.547 0.453
E00 Congenital iodine-deficiency syndrome
0.000 0.547 0.453
E07 Other disorders of thyroid
0.000 0.552 0.448
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.554 0.446
E03.5 Myxoedema coma
0.000 0.555 0.445
E03.4 Atrophy of thyroid (acquired)
0.000 0.555 0.445
E03.3 Postinfectious hypothyroidism
0.000 0.555 0.445
E03.1 Congenital hypothyroidism without goitre
0.000 0.555 0.445
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.555 0.445
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.557 0.443
E32 Diseases of thymus
0.000 0.557 0.443
E31 Polyglandular dysfunction
0.000 0.557 0.443
E30 Disorders of puberty, not elsewhere classified
0.000 0.557 0.443
E25 Adrenogenital disorders
0.000 0.557 0.443
E29 Testicular dysfunction
0.000 0.561 0.439
E05.9 Thyrotoxicosis, unspecified
0.000 0.562 0.437
E26.0 Primary hyperaldosteronism
0.000 0.572 0.428
M16.1 Other primary coxarthrosis
0.000 0.573 0.427
E34 Other endocrine disorders
0.000 0.573 0.426
E27.8 Other specified disorders of adrenal gland
0.000 0.578 0.422
E20 Hypoparathyroidism
0.000 0.579 0.421
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.580 0.420
E06.3 Autoimmune thyroiditis
0.000 0.582 0.418
E05.5 Thyroid crisis or storm
0.000 0.584 0.416
E05.4 Thyrotoxicosis factitia
0.000 0.584 0.416
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.584 0.416
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.584 0.416
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.585 0.415
E28.3 Primary ovarian failure
0.000 0.586 0.414
E04 Other non-toxic goitre
0.000 0.587 0.413
M16 Coxarthrosis [arthrosis of hip]
0.000 0.589 0.411
E23.2 Diabetes insipidus
0.000 0.596 0.404
E27.1 Primary adrenocortical insufficiency
0.000 0.596 0.404
M16.9 Coxarthrosis, unspecified
0.000 0.598 0.402
E22.1 Hyperprolactinaemia
0.000 0.603 0.397
E27.2 Addisonian crisis
0.000 0.606 0.394
E27.9 Disorder of adrenal gland, unspecified
0.000 0.617 0.383
E28.9 Ovarian dysfunction, unspecified
0.000 0.618 0.382
E28.8 Other ovarian dysfunction
0.000 0.618 0.382
E28.1 Androgen excess
0.000 0.618 0.382
E28.0 Oestrogen excess
0.000 0.618 0.382
E05.8 Other thyrotoxicosis
0.000 0.622 0.378
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.623 0.377
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.627 0.373
E22.8 Other hyperfunction of pituitary gland
0.000 0.627 0.373
E24.8 Other Cushing's syndrome
0.000 0.627 0.372
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.627 0.372
E24.3 Ectopic ACTH syndrome
0.000 0.627 0.372
E24.1 Nelson's syndrome
0.000 0.627 0.372
E24.0 Pituitary-dependent Cushing's disease
0.000 0.627 0.372
E46 Unspecified protein-energy malnutrition
0.000 0.633 0.367
E26.9 Hyperaldosteronism, unspecified
0.000 0.636 0.364
E26.8 Other hyperaldosteronism
0.000 0.636 0.364
E26.1 Secondary hyperaldosteronism
0.000 0.636 0.364
E27.5 Adrenomedullary hyperfunction
0.000 0.637 0.363
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.637 0.363
E27.0 Other adrenocortical overactivity
0.000 0.637 0.363
M16.7 Other secondary coxarthrosis
0.000 0.639 0.361
E06.5 Other chronic thyroiditis
0.000 0.640 0.360
E06.4 Drug-induced thyroiditis
0.000 0.640 0.360
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.640 0.360
E06.1 Subacute thyroiditis
0.000 0.640 0.360
E06.0 Acute thyroiditis
0.000 0.640 0.360
E12.9 Without complications
0.000 0.648 0.352
E12.8 With unspecified complications
0.000 0.648 0.352
E12.7 With multiple complications
0.000 0.648 0.352
E12.6 With other specified complications
0.000 0.648 0.352
E12.5 With peripheral circulatory complications
0.000 0.648 0.352
E12.4 With neurological complications
0.000 0.648 0.352
E12.3 With ophthalmic complications
0.000 0.648 0.352
E12.2 With renal complications
0.000 0.648 0.352
E12.1 With ketoacidosis
0.000 0.648 0.352
E12.0 With coma
0.000 0.648 0.352
E24.2 Drug-induced Cushing's syndrome
0.000 0.648 0.351
E13.8 With unspecified complications
0.000 0.655 0.345
E13.7 With multiple complications
0.000 0.655 0.345
E13.6 With other specified complications
0.000 0.655 0.345
E13.5 With peripheral circulatory complications
0.000 0.655 0.345
E13.4 With neurological complications
0.000 0.655 0.345
E13.3 With ophthalmic complications
0.000 0.655 0.345
E13.2 With renal complications
0.000 0.655 0.345
E13.1 With ketoacidosis
0.000 0.655 0.345
E13.0 With coma
0.000 0.655 0.345
E06.9 Thyroiditis, unspecified
0.000 0.655 0.344
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.656 0.343
E45 Retarded development following protein-energy malnutrition
0.000 0.656 0.343
E43 Unspecified severe protein-energy malnutrition
0.000 0.656 0.343
E42 Marasmic kwashiorkor
0.000 0.656 0.343
E41 Nutritional marasmus
0.000 0.656 0.343
E40 Kwashiorkor
0.000 0.656 0.343
E04.9 Non-toxic goitre, unspecified
0.000 0.660 0.340
E23.6 Other disorders of pituitary gland
0.000 0.663 0.337
E13.9 Without complications
0.000 0.664 0.336
E23.7 Disorder of pituitary gland, unspecified
0.000 0.665 0.335
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.665 0.335
E23.1 Drug-induced hypopituitarism
0.000 0.665 0.335
M16.3 Other dysplastic coxarthrosis
0.000 0.666 0.334
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.669 0.331
E07.8 Other specified disorders of thyroid
0.000 0.669 0.331
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.675 0.325
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.675 0.325
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.675 0.325
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.675 0.325
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.675 0.325
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.675 0.325
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.675 0.325
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.675 0.325
E34.0 Carcinoid syndrome
0.000 0.675 0.324
E07.1 Dyshormogenetic goitre
0.000 0.678 0.322
E07.0 Hypersecretion of calcitonin
0.000 0.678 0.322
E25.9 Adrenogenital disorder, unspecified
0.000 0.682 0.317
E25.8 Other adrenogenital disorders
0.000 0.682 0.317
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.682 0.317
E30.9 Disorder of puberty, unspecified
0.000 0.682 0.317
E30.8 Other disorders of puberty
0.000 0.682 0.317
E30.1 Precocious puberty
0.000 0.682 0.317
E30.0 Delayed puberty
0.000 0.682 0.317
E31.9 Polyglandular dysfunction, unspecified
0.000 0.682 0.317
E31.8 Other polyglandular dysfunction
0.000 0.682 0.317
E31.1 Polyglandular hyperfunction
0.000 0.682 0.317
E31.0 Autoimmune polyglandular failure
0.000 0.682 0.317
E32.9 Disease of thymus, unspecified
0.000 0.682 0.317
E32.8 Other diseases of thymus
0.000 0.682 0.317
E32.1 Abscess of thymus
0.000 0.682 0.317
E32.0 Persistent hyperplasia of thymus
0.000 0.682 0.317
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.682 0.317
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.682 0.317
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.682 0.317
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.684 0.316
E29.9 Testicular dysfunction, unspecified
0.000 0.685 0.315
E29.8 Other testicular dysfunction
0.000 0.685 0.315
E29.0 Testicular hyperfunction
0.000 0.685 0.315
E11 Non-insulin-dependent diabetes mellitus
0.000 0.689 0.311
E29.1 Testicular hypofunction
0.000 0.689 0.311
E04.1 Non-toxic single thyroid nodule
0.000 0.690 0.310
E04.0 Non-toxic diffuse goitre
0.000 0.693 0.307
E07.9 Disorder of thyroid, unspecified
0.000 0.694 0.306
E34.5 Androgen resistance syndrome
0.000 0.694 0.306
E34.4 Constitutional tall stature
0.000 0.694 0.306
E34.3 Short stature, not elsewhere classified
0.000 0.694 0.306
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.694 0.306
E34.1 Other hypersecretion of intestinal hormones
0.000 0.694 0.306
E20.8 Other hypoparathyroidism
0.000 0.698 0.302
E20.1 Pseudohypoparathyroidism
0.000 0.698 0.302
E20.0 Idiopathic hypoparathyroidism
0.000 0.698 0.302
M16.0 Primary coxarthrosis, bilateral
0.000 0.701 0.299
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.703 0.297
E21.4 Other specified disorders of parathyroid gland
0.000 0.703 0.297
E21.2 Other hyperparathyroidism
0.000 0.703 0.297
E04.8 Other specified non-toxic goitre
0.000 0.704 0.296
M16.6 Other secondary coxarthrosis, bilateral
0.000 0.705 0.295
M16.4 Posttraumatic coxarthrosis, bilateral
0.000 0.705 0.295
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.000 0.705 0.295
E34.8 Other specified endocrine disorders
0.000 0.707 0.293
E65-E68 Obesity and other hyperalimentation
0.000 0.708 0.291
E34.9 Endocrine disorder, unspecified
0.000 0.719 0.280
E20.9 Hypoparathyroidism, unspecified
0.000 0.720 0.280
E21.0 Primary hyperparathyroidism
0.000 0.721 0.279
E15 Nondiabetic hypoglycaemic coma
0.000 0.729 0.270
M16.5 Other posttraumatic coxarthrosis
0.000 0.730 0.270
E21.3 Hyperparathyroidism, unspecified
0.000 0.734 0.266
E11.1 With ketoacidosis
0.000 0.736 0.264
E11.4 With neurological complications
0.000 0.740 0.260
E44.1 Mild protein-energy malnutrition
0.000 0.753 0.246
E44.0 Moderate protein-energy malnutrition
0.000 0.753 0.246
E14 Unspecified diabetes mellitus
0.000 0.756 0.244
E23.0 Hypopituitarism
0.000 0.759 0.241
E50-E64 Other nutritional deficiencies
0.000 0.763 0.236
E11.2 With renal complications
0.000 0.772 0.228
E11.0 With coma
0.000 0.773 0.227
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.776 0.223
E11.7 With multiple complications
0.000 0.776 0.223
E67 Other hyperalimentation
0.000 0.791 0.209
E68 Sequelae of hyperalimentation
0.000 0.791 0.209
E11.8 With unspecified complications
0.000 0.791 0.209
E11.5 With peripheral circulatory complications
0.000 0.797 0.203
E16 Other disorders of pancreatic internal secretion
0.000 0.808 0.192
E11.3 With ophthalmic complications
0.000 0.812 0.188
E66 Obesity
0.000 0.814 0.186
E14.8 With unspecified complications
0.000 0.825 0.175
E14.7 With multiple complications
0.000 0.825 0.175
E14.6 With other specified complications
0.000 0.825 0.175
E14.5 With peripheral circulatory complications
0.000 0.825 0.175
E14.4 With neurological complications
0.000 0.825 0.175
E14.2 Withrenal complications
0.000 0.825 0.175
E14.1 With ketoacidosis
0.000 0.825 0.175
E14.0 With coma
0.000 0.825 0.175
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.830 0.170
E63 Other nutritional deficiencies
0.000 0.830 0.170
E56 Other vitamin deficiencies
0.000 0.830 0.170
E51 Thiamine deficiency
0.000 0.830 0.170
E50 Vitamin A deficiency
0.000 0.830 0.170
E60 Dietary zinc deficiency
0.000 0.830 0.170
E59 Dietary selenium deficiency
0.000 0.830 0.170
E54 Ascorbic acid deficiency
0.000 0.830 0.170
E52 Niacin deficiency [pellagra]
0.000 0.830 0.170
E11.6 With other specified complications
0.000 0.833 0.167
E55 Vitamin D deficiency
0.000 0.839 0.161
E67.8 Other specified hyperalimentation
0.000 0.850 0.150
E67.3 Hypervitaminosis D
0.000 0.850 0.150
E67.2 Megavitamin-B6 syndrome
0.000 0.850 0.150
E67.1 Hypercarotenaemia
0.000 0.850 0.150
E67.0 Hypervitaminosis A
0.000 0.850 0.150
E66.8 Other obesity
0.000 0.855 0.145
E58 Dietary calcium deficiency
0.000 0.858 0.142
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.862 0.138
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.862 0.138
E16.4 Abnormal secretion of gastrin
0.000 0.862 0.138
E16.3 Increased secretion of glucagon
0.000 0.862 0.138
E66.0 Obesity due to excess calories
0.000 0.863 0.137
E61 Deficiency of other nutrient elements
0.000 0.863 0.137
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.866 0.134
E66.1 Drug-induced obesity
0.000 0.866 0.134
E16.1 Other hypoglycaemia
0.000 0.869 0.131
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.873 0.127
E50.9 Vitamin A deficiency, unspecified
0.000 0.878 0.122
E50.8 Other manifestations of vitamin A deficiency
0.000 0.878 0.122
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.878 0.122
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.878 0.122
E50.5 Vitamin A deficiency with night blindness
0.000 0.878 0.122
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.878 0.122
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.878 0.122
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.878 0.122
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.878 0.122
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.878 0.122
E51.9 Thiamine deficiency, unspecified
0.000 0.878 0.122
E51.8 Other manifestations of thiamine deficiency
0.000 0.878 0.122
E51.2 Wernicke's encephalopathy
0.000 0.878 0.122
E51.1 Beriberi
0.000 0.878 0.122
E56.9 Vitamin deficiency, unspecified
0.000 0.878 0.122
E56.8 Deficiency of other vitamins
0.000 0.878 0.122
E56.1 Deficiency of vitamin K
0.000 0.878 0.122
E56.0 Deficiency of vitamin E
0.000 0.878 0.122
E63.9 Nutritional deficiency, unspecified
0.000 0.878 0.122
E63.8 Other specified nutritional deficiencies
0.000 0.878 0.122
E63.1 Imbalance of constituents of food intake
0.000 0.878 0.122
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.878 0.122
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.878 0.122
E64.8 Sequelae of other nutritional deficiencies
0.000 0.878 0.122
E64.3 Sequelae of rickets
0.000 0.878 0.122
E64.2 Sequelae of vitamin C deficiency
0.000 0.878 0.122
E64.1 Sequelae of vitamin A deficiency
0.000 0.878 0.122
E64.0 Sequelae of protein-energy malnutrition
0.000 0.878 0.122
E53 Deficiency of other B group vitamins
0.000 0.883 0.117
E55.0 Rickets, active
0.000 0.884 0.115
E14.3 With ophthalmic complications
0.000 0.888 0.112
E55.9 Vitamin D deficiency, unspecified
0.000 0.893 0.107
E04.2 Non-toxic multinodular goitre
0.000 0.900 0.100
E65 Localised adiposity
0.001 0.900 0.098
E61.9 Deficiency of nutrient element, unspecified
0.000 0.902 0.098
E61.8 Deficiency of other specified nutrient elements
0.000 0.902 0.098
E61.7 Deficiency of multiple nutrient elements
0.000 0.902 0.098
E61.6 Vanadium deficiency
0.000 0.902 0.098
E61.5 Molybdenum deficiency
0.000 0.902 0.098
E61.4 Chromium deficiency
0.000 0.902 0.098
E61.3 Manganese deficiency
0.000 0.902 0.098
E61.2 Magnesium deficiency
0.000 0.902 0.098
E61.0 Copper deficiency
0.000 0.902 0.098
E16.2 Hypoglycaemia, unspecified
0.000 0.907 0.093
E53.1 Pyridoxine deficiency
0.000 0.916 0.084
E53.0 Riboflavin deficiency
0.000 0.916 0.084
E66.9 Obesity, unspecified
0.000 0.917 0.083
E53.9 Vitamin B deficiency, unspecified
0.000 0.919 0.081
E14.9 Without complications
0.000 0.921 0.079
E61.1 Iron deficiency
0.000 0.935 0.065
M20.5 Other deformities of toe(s) (acquired)
0.000 0.951 0.049
M15-M19 Arthrosis
0.000 0.954 0.046
M19.0 Primary arthrosis of other joints
0.000 0.961 0.039
M20.4 Other hammer toe(s) (acquired)
0.000 0.961 0.039
M20 Acquired deformities of fingers and toes
0.000 0.962 0.038
M19.01 Primary arthrosis of other joints (Shoulder region)
0.000 0.962 0.038
M19 Other arthrosis
0.000 0.962 0.038
E53.8 Deficiency of other specified B group vitamins
0.000 0.962 0.038
M20.2 Hallux rigidus
0.000 0.965 0.035
E70-E90 Metabolic disorders
0.000 0.967 0.033
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.967 0.033
M19.04 Primary arthrosis of other joints (Hand)
0.000 0.968 0.032
M19.03 Primary arthrosis of other joints (Forearm)
0.000 0.968 0.032
M15 Polyarthrosis
0.000 0.970 0.030
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.970 0.030
M19.09 Primary arthrosis of other joints (Site unspecified)
0.000 0.970 0.030
M19.02 Primary arthrosis of other joints (Upper arm)
0.000 0.970 0.030
E89.0 Postprocedural hypothyroidism
0.000 0.970 0.030
E11.9 Without complications
0.000 0.970 0.030
M19.08 Primary arthrosis of other joints (Other)
0.000 0.972 0.028
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.000 0.972 0.028
M19.8 Other specified arthrosis
0.000 0.973 0.027
M19.06 Primary arthrosis of other joints-Lower leg
0.000 0.974 0.026
L30.9 Dermatitis, unspecified
0.026 0.974 0.000
M19.2 Other secondary arthrosis
0.000 0.974 0.026
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.000 0.975 0.025
M19.00 Primary arthrosis of other joints (Multiple sites)
0.000 0.975 0.025
E74 Other disorders of carbohydrate metabolism
0.000 0.976 0.024
E84 Cystic fibrosis
0.000 0.976 0.024
E79 Disorders of purine and pyrimidine metabolism
0.000 0.976 0.024
E77 Disorders of glycoprotein metabolism
0.000 0.976 0.024
E76 Disorders of glycosaminoglycan metabolism
0.000 0.976 0.024
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.976 0.024
E72 Other disorders of amino-acid metabolism
0.000 0.976 0.024
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.976 0.024
E70 Disorders of aromatic amino-acid metabolism
0.000 0.976 0.024
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.976 0.024
E85 Amyloidosis
0.000 0.976 0.023
M19.1 Posttraumatic arthrosis of other joints
0.000 0.977 0.023
M20.3 Other deformity of hallux (acquired)
0.000 0.977 0.023
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.977 0.023
M15.2 Bouchard's nodes (with arthropathy)
0.000 0.977 0.022
M15.9 Polyarthrosis, unspecified
0.000 0.978 0.022
M15.0 Primary generalised (osteo)arthrosis
0.000 0.978 0.022
M15.8 Other polyarthrosis
0.000 0.978 0.022
M15.4 Erosive (osteo)arthrosis
0.000 0.978 0.022
M15.3 Secondary multiple arthrosis
0.000 0.978 0.022
E73 Lactose intolerance
0.000 0.978 0.022
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.978 0.022
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.978 0.022
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.978 0.022
E89.5 Postprocedural testicular hypofunction
0.000 0.978 0.022
E89.4 Postprocedural ovarian failure
0.000 0.978 0.022
E89.1 Postprocedural hypoinsulinaemia
0.000 0.978 0.022
E88 Other metabolic disorders
0.000 0.978 0.022
M20.0 Deformity of finger(s)
0.000 0.978 0.022
E89.3 Postprocedural hypopituitarism
0.000 0.979 0.021
Z34.8 Supervision of other normal pregnancy
0.000 0.979 0.021
A08.4 Viral intestinal infection, unspecified
0.020 0.980 0.000
M19.89 Other specified arthrosis (Site unspecified)
0.000 0.980 0.020
M19.88 Other specified arthrosis (Other)
0.000 0.980 0.020
M19.87 Other specified arthrosis (Ankle and foot)
0.000 0.980 0.020
M19.86 Other specified arthrosis (Lower leg)
0.000 0.980 0.020
M19.85 Other specified arthrosis (Pelvic region and thigh)
0.000 0.980 0.020
M19.84 Other specified arthrosis (Hand)
0.000 0.980 0.020
M19.83 Other specified arthrosis (Forearm)
0.000 0.980 0.020
M19.82 Other specified arthrosis (Upper arm)
0.000 0.980 0.020
M19.81 Other specified arthrosis (Shoulder region)
0.000 0.980 0.020
M19.80 Other specified arthrosis (Multiple sites)
0.000 0.980 0.020
Y43.3 Other antineoplastic drugs
0.019 0.981 0.000
M15.1 Heberden's nodes (with arthropathy)
0.000 0.981 0.019
M19.29 Other secondary arthrosis (Site unspecified)
0.000 0.981 0.018
M19.28 Other secondary arthrosis (Other)
0.000 0.981 0.018
M19.26 Other secondary arthrosis of other joints-Lower leg
0.000 0.981 0.018
M19.25 Other secondary arthrosis (Pelvic region and thigh)
0.000 0.981 0.018
M19.24 Other secondary arthrosis (Hand)
0.000 0.981 0.018
M19.23 Other secondary arthrosis (Forearm)
0.000 0.981 0.018
M19.22 Other secondary arthrosis (Upper arm)
0.000 0.981 0.018
M19.21 Other secondary arthrosis (Shoulder region)
0.000 0.981 0.018
M19.20 Other secondary arthrosis (Multiple sites)
0.000 0.981 0.018
E89.2 Postprocedural hypoparathyroidism
0.000 0.982 0.018
E85.9 Amyloidosis, unspecified
0.000 0.982 0.018
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.982 0.018
A08 Viral and other specified intestinal infections
0.018 0.982 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.982 0.017
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.982 0.017
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.982 0.017
E74.2 Disorders of galactose metabolism
0.000 0.982 0.017
E74.1 Disorders of fructose metabolism
0.000 0.982 0.017
E74.0 Glycogen storage disease
0.000 0.982 0.017
I61.9 Intracerebral haemorrhage, unspecified
0.017 0.983 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.983 0.017
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.983 0.017
E70.3 Albinism
0.000 0.983 0.017
E70.2 Disorders of tyrosine metabolism
0.000 0.983 0.017
E70.1 Other hyperphenylalaninaemias
0.000 0.983 0.017
E70.0 Classical phenylketonuria
0.000 0.983 0.017
E71.3 Disorders of fatty-acid metabolism
0.000 0.983 0.017
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.983 0.017
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.983 0.017
E71.0 Maple-syrup-urine disease
0.000 0.983 0.017
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.983 0.017
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.983 0.017
E72.5 Disorders of glycine metabolism
0.000 0.983 0.017
E72.4 Disorders of ornithine metabolism
0.000 0.983 0.017
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.983 0.017
E72.2 Disorders of urea cycle metabolism
0.000 0.983 0.017
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.983 0.017
E72.0 Disorders of amino-acid transport
0.000 0.983 0.017
E75.6 Lipid storage disorder, unspecified
0.000 0.983 0.017
E75.5 Other lipid storage disorders
0.000 0.983 0.017
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.983 0.017
E75.3 Sphingolipidosis, unspecified
0.000 0.983 0.017
E75.2 Other sphingolipidosis
0.000 0.983 0.017
E75.1 Other gangliosidosis
0.000 0.983 0.017
E75.0 GM2 gangliosidosis
0.000 0.983 0.017
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.983 0.017
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.983 0.017
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.983 0.017
E76.2 Other mucopolysaccharidoses
0.000 0.983 0.017
E76.1 Mucopolysaccharidosis, type II
0.000 0.983 0.017
E76.0 Mucopolysaccharidosis, type I
0.000 0.983 0.017
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.983 0.017
E77.8 Other disorders of glycoprotein metabolism
0.000 0.983 0.017
E77.1 Defects in glycoprotein degradation
0.000 0.983 0.017
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.983 0.017
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.983 0.017
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.983 0.017
E79.1 Lesch-Nyhan syndrome
0.000 0.983 0.017
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.983 0.017
E84.9 Cystic fibrosis, unspecified
0.000 0.983 0.017
E84.8 Cystic fibrosis with other manifestations
0.000 0.983 0.017
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.983 0.017
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.983 0.017
E85.8 Other amyloidosis
0.000 0.983 0.017
E85.3 Secondary systemic amyloidosis
0.000 0.983 0.017
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.983 0.017
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.983 0.017
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.983 0.017
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)
0.000 0.983 0.017
M19.27 Other secondary arthrosis (Ankle and foot)
0.000 0.983 0.017
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)
0.000 0.983 0.017
M19.18 Post-traumatic arthrosis of other joints (Other)
0.000 0.983 0.017
M19.16 Post-traumatic arthrosis of other joints-Lower leg
0.000 0.983 0.017
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)
0.000 0.983 0.017
M19.13 Post-traumatic arthrosis of other joints (Forearm)
0.000 0.983 0.017
M19.12 Post-traumatic arthrosis of other joints (Upper arm)
0.000 0.983 0.017
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)
0.000 0.983 0.017
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.983 0.016
E80.6 Other disorders of bilirubin metabolism
0.000 0.983 0.016
E80.5 Crigler-Najjar syndrome
0.000 0.983 0.016
E80.3 Defects of catalase and peroxydase
0.000 0.983 0.016
E80.2 Other porphyria
0.000 0.983 0.016
E80.1 Porphyria cutanea tarda
0.000 0.983 0.016
E80.0 Hereditary erythropoietic porphyria
0.000 0.983 0.016
I67.8 Other specified cerebrovascular diseases
0.016 0.984 0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites
0.000 0.984 0.016
M15.99 Polyosteoarthritis, unspecified
0.000 0.984 0.016
E73.8 Other lactose intolerance
0.000 0.984 0.016
E73.1 Secondary lactase deficiency
0.000 0.984 0.016
E73.0 Congenital lactase deficiency
0.000 0.984 0.016
E85.4 Organ-limited amyloidosis
0.000 0.984 0.016
E88.9 Metabolic disorder, unspecified
0.000 0.984 0.016
E88.8 Other specified metabolic disorders
0.000 0.984 0.016
E88.3 Tumour lysis syndrome
0.000 0.984 0.016
E88.2 Lipomatosis, not elsewhere classified
0.000 0.984 0.016
I60-I69 Cerebrovascular diseases
0.016 0.984 0.000
E80.4 Gilbert's syndrome
0.000 0.984 0.016
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.984 0.016
I60 Subarachnoid haemorrhage
0.016 0.984 0.000
I67 Other cerebrovascular diseases
0.016 0.984 0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)
0.000 0.984 0.015
I61 Intracerebral haemorrhage
0.016 0.984 0.000
A08.3 Other viral enteritis
0.016 0.984 0.000
M18 Arthrosis of first carpometacarpal joint
0.000 0.984 0.015
I67.1 Cerebral aneurysm, nonruptured
0.014 0.986 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.014 0.986 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.986 0.014
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.000 0.986 0.014
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.986 0.014
I60.9 Subarachnoid haemorrhage, unspecified
0.014 0.986 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.014 0.986 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.014 0.986 0.000
L30 Other dermatitis
0.014 0.986 0.000
I69 Sequelae of cerebrovascular disease
0.014 0.986 0.000
A08.5 Other specified intestinal infections
0.013 0.987 0.000
A08.2 Adenoviral enteritis
0.013 0.987 0.000
A08.0 Rotaviral enteritis
0.013 0.987 0.000
I63 Cerebral infarction
0.013 0.987 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.012 0.988 0.000
Y43 Primarily systemic agents
0.012 0.988 0.000
I63.9 Cerebral infarction, unspecified
0.012 0.988 0.000
A00-A09 Intestinal infectious diseases
0.012 0.988 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.011 0.988 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.011 0.988 0.000
I69.3 Sequelae of cerebral infarction
0.012 0.988 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.011 0.988 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.011 0.989 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.011 0.989 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.011 0.989 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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