TreeWAS – Variant ID: rs1275468

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.3 With ophthalmic complications	0.000	0.934	0.066
E10 Insulin-dependent diabetes mellitus	0.000	0.934	0.066
E11.4 With neurological complications	0.000	0.937	0.063
E11 Non-insulin-dependent diabetes mellitus	0.000	0.938	0.062
E10.4 With neurological complications	0.000	0.938	0.062
E10.2 With renal complications	0.000	0.939	0.061
T43.2 Other and unspecified antidepressants	0.060	0.940	0.000
E10-E14 Diabetes mellitus	0.000	0.941	0.059
E10.6 With other specified complications	0.000	0.942	0.058
E11.3 With ophthalmic complications	0.000	0.943	0.057
E11.1 With ketoacidosis	0.000	0.946	0.054
E11.2 With renal complications	0.000	0.948	0.052
E10.0 With coma	0.000	0.950	0.050
E10.8 With unspecified complications	0.000	0.951	0.049
E10.5 With peripheral circulatory complications	0.000	0.952	0.047
Z91.5 Personal history of self-harm	0.047	0.953	0.000
E10.7 With multiple complications	0.000	0.953	0.047
E11.0 With coma	0.000	0.954	0.046
E11.7 With multiple complications	0.000	0.954	0.046
E11.5 With peripheral circulatory complications	0.000	0.955	0.045
E11.8 With unspecified complications	0.000	0.955	0.045
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.044	0.956	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.957	0.042
T43.5 Other and unspecified antipsychotics and neuroleptics	0.042	0.958	0.000
E11.6 With other specified complications	0.000	0.960	0.040
T43.4 Butyrophenone and thioxanthene neuroleptics	0.036	0.963	0.000
E13 Other specified diabetes mellitus	0.000	0.966	0.034
T43.6 Psychostimulants with abuse potential	0.033	0.967	0.000
E14 Unspecified diabetes mellitus	0.000	0.968	0.032
T43.8 Other psychotropic drugs, not elsewhere classified	0.031	0.968	0.000
T43.9 Psychotropic drug, unspecified	0.031	0.969	0.000
E12.9 Without complications	0.000	0.969	0.031
E12.8 With unspecified complications	0.000	0.969	0.031
E12.7 With multiple complications	0.000	0.969	0.031
E12.6 With other specified complications	0.000	0.969	0.031
E12.5 With peripheral circulatory complications	0.000	0.969	0.031
E12.4 With neurological complications	0.000	0.969	0.031
E12.3 With ophthalmic complications	0.000	0.969	0.031
E12.2 With renal complications	0.000	0.969	0.031
E12.1 With ketoacidosis	0.000	0.969	0.031
E12.0 With coma	0.000	0.969	0.031
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.029	0.971	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.028	0.972	0.000
E14.1 With ketoacidosis	0.000	0.972	0.028
E10.1 With ketoacidosis	0.000	0.975	0.025
E14.6 With other specified complications	0.000	0.975	0.025
E13.3 With ophthalmic complications	0.000	0.975	0.024
E13.8 With unspecified complications	0.000	0.976	0.024
E13.7 With multiple complications	0.000	0.976	0.024
E13.6 With other specified complications	0.000	0.976	0.024
E13.5 With peripheral circulatory complications	0.000	0.976	0.024
E13.4 With neurological complications	0.000	0.976	0.024
E13.2 With renal complications	0.000	0.976	0.024
E13.1 With ketoacidosis	0.000	0.976	0.024
E13.0 With coma	0.000	0.976	0.024
E14.2 Withrenal complications	0.000	0.976	0.024
E14.5 With peripheral circulatory complications	0.000	0.976	0.024
E14.7 With multiple complications	0.000	0.977	0.023
E14.4 With neurological complications	0.000	0.977	0.023
E55.9 Vitamin D deficiency, unspecified	0.000	0.977	0.023
T43.0 Tricyclic and tetracyclic antidepressants	0.022	0.978	0.000
E14.0 With coma	0.000	0.978	0.022
E14.8 With unspecified complications	0.000	0.978	0.022
E14.3 With ophthalmic complications	0.000	0.980	0.020
H83.0 Labyrinthitis	0.000	0.981	0.019
E55 Vitamin D deficiency	0.000	0.981	0.019
E50-E64 Other nutritional deficiencies	0.000	0.984	0.016
E13.9 Without complications	0.000	0.985	0.015
B18.2 Chronic viral hepatitis C	0.015	0.985	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.014	0.986	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.986	0.014
E55.0 Rickets, active	0.000	0.986	0.013
E16.2 Hypoglycaemia, unspecified	0.000	0.986	0.014
E53 Deficiency of other B group vitamins	0.000	0.987	0.013
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.987	0.013
B18 Chronic viral hepatitis	0.013	0.987	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.987	0.012
B18.1 Chronic viral hepatitis B without delta-agent	0.012	0.988	0.000
E51 Thiamine deficiency	0.000	0.988	0.012
D80.1 Nonfamilial hypogammaglobulinaemia	0.012	0.988	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.988	0.012
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.988	0.012
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.989	0.011
E50 Vitamin A deficiency	0.000	0.989	0.011
E60 Dietary zinc deficiency	0.000	0.989	0.011
E59 Dietary selenium deficiency	0.000	0.989	0.011
E52 Niacin deficiency [pellagra]	0.000	0.989	0.011
E63 Other nutritional deficiencies	0.000	0.989	0.011
D80 Immunodeficiency with predominantly antibody defects	0.011	0.989	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.989	0.011
E54 Ascorbic acid deficiency	0.000	0.989	0.011
H83 Other diseases of inner ear	0.000	0.989	0.011
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.989	0.011
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.010	0.990	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.990	0.010
E56 Other vitamin deficiencies	0.000	0.990	0.010
E58 Dietary calcium deficiency	0.000	0.990	0.010
E40-E46 Malnutrition	0.000	0.990	0.010
E53.1 Pyridoxine deficiency	0.000	0.990	0.010
E53.0 Riboflavin deficiency	0.000	0.990	0.010
B15-B19 Viral hepatitis	0.010	0.990	0.000
E51.2 Wernicke's encephalopathy	0.000	0.990	0.010
E15 Nondiabetic hypoglycaemic coma	0.000	0.990	0.010
B18.8 Other chronic viral hepatitis	0.010	0.990	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.010	0.990	0.000
B18.9 Chronic viral hepatitis, unspecified	0.009	0.990	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.991	0.009
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.991	0.009
E16.4 Abnormal secretion of gastrin	0.000	0.991	0.009
E16.3 Increased secretion of glucagon	0.000	0.991	0.009
H83.3 Noise effects on inner ear	0.000	0.991	0.009
E51.9 Thiamine deficiency, unspecified	0.000	0.991	0.009
E51.8 Other manifestations of thiamine deficiency	0.000	0.991	0.009
E51.1 Beriberi	0.000	0.991	0.009
E53.9 Vitamin B deficiency, unspecified	0.000	0.991	0.009
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.009	0.991	0.000
B15 Acute hepatitis A	0.009	0.991	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.009	0.991	0.000
E61 Deficiency of other nutrient elements	0.000	0.991	0.009
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.009	0.991	0.000
B17 Other acute viral hepatitis	0.008	0.991	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.992	0.008
E50.8 Other manifestations of vitamin A deficiency	0.000	0.992	0.008
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.992	0.008
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.992	0.008
E50.5 Vitamin A deficiency with night blindness	0.000	0.992	0.008
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.992	0.008
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.992	0.008
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.992	0.008
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.992	0.008
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.992	0.008
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.992	0.008
E64.8 Sequelae of other nutritional deficiencies	0.000	0.992	0.008
E64.3 Sequelae of rickets	0.000	0.992	0.008
E64.2 Sequelae of vitamin C deficiency	0.000	0.992	0.008
E64.1 Sequelae of vitamin A deficiency	0.000	0.992	0.008
E64.0 Sequelae of protein-energy malnutrition	0.000	0.992	0.008
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.008	0.992	0.000
E63.8 Other specified nutritional deficiencies	0.000	0.992	0.008
E63.1 Imbalance of constituents of food intake	0.000	0.992	0.008
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.992	0.008
B15.9 Hepatitis A without hepatic coma	0.008	0.992	0.000
E63.9 Nutritional deficiency, unspecified	0.000	0.992	0.008
H83.8 Other specified diseases of inner ear	0.000	0.992	0.008
D80.7 Transient hypogammaglobulinaemia of infancy	0.008	0.992	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.008	0.992	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.008	0.992	0.000
E16.1 Other hypoglycaemia	0.000	0.992	0.008
H83.1 Labyrinthine fistula	0.000	0.992	0.008
E20-E35 Disorders of other endocrine glands	0.000	0.992	0.008
D80.8 Other immunodeficiencies with predominantly antibody defects	0.008	0.992	0.000
H83.2 Labyrinthine dysfunction	0.000	0.992	0.008
H66.9 Otitis media, unspecified	0.000	0.992	0.008
I27.2 Other secondary pulmonary hypertension	0.000	0.992	0.008
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.992	0.007
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.992	0.007
B17.1 Acute hepatitis C	0.008	0.992	0.000
E56.9 Vitamin deficiency, unspecified	0.000	0.992	0.007
E56.8 Deficiency of other vitamins	0.000	0.992	0.007
E56.0 Deficiency of vitamin E	0.000	0.992	0.007
B19 Unspecified viral hepatitis	0.007	0.992	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.993	0.007
E45 Retarded development following protein-energy malnutrition	0.000	0.993	0.007
E43 Unspecified severe protein-energy malnutrition	0.000	0.993	0.007
E42 Marasmic kwashiorkor	0.000	0.993	0.007
E41 Nutritional marasmus	0.000	0.993	0.007
E40 Kwashiorkor	0.000	0.993	0.007
B16 Acute hepatitis B	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.000	0.993	0.007
E26 Hyperaldosteronism	0.000	0.993	0.007
E22.1 Hyperprolactinaemia	0.000	0.993	0.007
E22 Hyperfunction of pituitary gland	0.000	0.993	0.007
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.993	0.007
H83.9 Disease of inner ear, unspecified	0.000	0.993	0.007
E24 Cushing's syndrome	0.000	0.993	0.007
B15.0 Hepatitis A with hepatic coma	0.006	0.993	0.000
Y84.8 Other medical procedures	0.000	0.993	0.007
B17.9 Acute viral hepatitis, unspecified	0.006	0.993	0.000
B17.8 Other specified acute viral hepatitis	0.006	0.993	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.993	0.006
G59.0 Diabetic mononeuropathy	0.000	0.993	0.007
E61.9 Deficiency of nutrient element, unspecified	0.000	0.993	0.006
E61.8 Deficiency of other specified nutrient elements	0.000	0.993	0.006
E61.7 Deficiency of multiple nutrient elements	0.000	0.993	0.006
E61.6 Vanadium deficiency	0.000	0.993	0.006
E61.5 Molybdenum deficiency	0.000	0.993	0.006
E61.4 Chromium deficiency	0.000	0.993	0.006
E61.3 Manganese deficiency	0.000	0.993	0.006
E61.0 Copper deficiency	0.000	0.993	0.006
E26.0 Primary hyperaldosteronism	0.000	0.994	0.006
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.000	0.994	0.006
E56.1 Deficiency of vitamin K	0.000	0.994	0.006
B17.2 Acute hepatitis E	0.006	0.994	0.000
E61.2 Magnesium deficiency	0.000	0.994	0.006
E27.8 Other specified disorders of adrenal gland	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.994	0.006
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E30 Disorders of puberty, not elsewhere classified	0.000	0.994	0.006
E27.9 Disorder of adrenal gland, unspecified	0.000	0.994	0.006
E25 Adrenogenital disorders	0.000	0.994	0.006
B19.9 Unspecified viral hepatitis without coma	0.006	0.994	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.994	0.006
B19.0 Unspecified viral hepatitis with coma	0.005	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.994	0.005
E44.1 Mild protein-energy malnutrition	0.000	0.994	0.005
E44.0 Moderate protein-energy malnutrition	0.000	0.994	0.005
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.005	0.995	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.005	0.995	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.005
E27.0 Other adrenocortical overactivity	0.000	0.995	0.005
E26.8 Other hyperaldosteronism	0.000	0.995	0.005
E26.1 Secondary hyperaldosteronism	0.000	0.995	0.005
E32 Diseases of thymus	0.000	0.995	0.005
M05.9 Seropositive rheumatoid arthritis, unspecified	0.005	0.995	0.000
E22.8 Other hyperfunction of pituitary gland	0.000	0.995	0.005
E24.0 Pituitary-dependent Cushing's disease	0.000	0.995	0.005
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.000	0.995	0.005
E29 Testicular dysfunction	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.000	0.995	0.005
E34 Other endocrine disorders	0.000	0.995	0.005
E20 Hypoparathyroidism	0.000	0.995	0.005
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.995	0.005
E24.3 Ectopic ACTH syndrome	0.000	0.995	0.005
E24.1 Nelson's syndrome	0.000	0.995	0.005
E24.2 Drug-induced Cushing's syndrome	0.000	0.995	0.005
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.995	0.005
J93.1 Other spontaneous pneumothorax	0.005	0.995	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.005	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.000	0.995	0.005
E31.8 Other polyglandular dysfunction	0.000	0.995	0.005
E31.1 Polyglandular hyperfunction	0.000	0.995	0.005
Z91 Personal history of risk-factors, not elsewhere classified	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.995	0.005
E27.1 Primary adrenocortical insufficiency	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
C62.9 Testis, unspecified	0.000	0.995	0.005
E30.9 Disorder of puberty, unspecified	0.000	0.995	0.004
E30.8 Other disorders of puberty	0.000	0.995	0.004
E30.1 Precocious puberty	0.000	0.995	0.004
E30.0 Delayed puberty	0.000	0.995	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.995	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.995	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.995	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.995	0.004
E25.8 Other adrenogenital disorders	0.000	0.995	0.004
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.004	0.995	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.995	0.004
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.995	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.995	0.004
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.995	0.004
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.996	0.004
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.996	0.004
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
E34.0 Carcinoid syndrome	0.000	0.996	0.004
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
R30.0 Dysuria	0.004	0.996	0.000
M10.94 Gout, unspecified (Hand)	0.004	0.996	0.000
N13.8 Other obstructive and reflux uropathy	0.004	0.996	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
E32.1 Abscess of thymus	0.000	0.996	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.996	0.004
E61.1 Iron deficiency	0.000	0.996	0.004
T23 Burn and corrosion of wrist and hand	0.000	0.996	0.004
E65-E68 Obesity and other hyperalimentation	0.000	0.996	0.004
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.996	0.004
E34.8 Other specified endocrine disorders	0.000	0.996	0.004
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.004
E29.8 Other testicular dysfunction	0.000	0.996	0.004
E29.0 Testicular hyperfunction	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.000	0.996	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.004
E34.5 Androgen resistance syndrome	0.000	0.996	0.004
E34.4 Constitutional tall stature	0.000	0.996	0.004
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.996	0.004
E34.1 Other hypersecretion of intestinal hormones	0.000	0.996	0.004
E32.8 Other diseases of thymus	0.000	0.996	0.004
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.004	0.996	0.000
N32.3 Diverticulum of bladder	0.000	0.996	0.004
M10.9 Gout, unspecified	0.004	0.996	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.000	0.996	0.004
D80-D89 Certain disorders involving the immune mechanism	0.004	0.996	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.996	0.004
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.004
Z91.7 Personal history of female genital mutilation	0.004	0.996	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.000	0.996	0.003
E23.2 Diabetes insipidus	0.000	0.996	0.004
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.004	0.996	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.996	0.004
E00-E07 Disorders of thyroid gland	0.000	0.996	0.004
G97.8 Other postprocedural disorders of nervous system	0.000	0.996	0.004
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.004	0.996	0.000
E28 Ovarian dysfunction	0.000	0.996	0.003
Z91.6 Personal history of other physical trauma	0.004	0.996	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.996	0.004
E29.1 Testicular hypofunction	0.000	0.996	0.003
T23.2 Burn of second degree of wrist and hand	0.000	0.996	0.004
Y84.4 Aspiration of fluid	0.000	0.996	0.004
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.996	0.003
Z91.2 Personal history of poor personal hygiene	0.003	0.996	0.000
T20 Burn and corrosion of head and neck	0.000	0.996	0.004
T25 Burn and corrosion of ankle and foot	0.000	0.996	0.003
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.996	0.004
E23.7 Disorder of pituitary gland, unspecified	0.000	0.996	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.996	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.996	0.003
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.996	0.003
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.996	0.003
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.996	0.003
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.996	0.003
T23.1 Burn of first degree of wrist and hand	0.000	0.997	0.003
I71 Aortic aneurysm and dissection	0.000	0.997	0.003
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T21 Burn and corrosion of trunk	0.000	0.997	0.003
M10.93 Gout, unspecified (Forearm)	0.003	0.997	0.000
M10.90 Gout, unspecified (Multiple sites)	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.997	0.003
T23.7 Corrosion of third degree of wrist and hand	0.000	0.997	0.003
T23.6 Corrosion of second degree of wrist and hand	0.000	0.997	0.003
T23.5 Corrosion of first degree of wrist and hand	0.000	0.997	0.003
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.997	0.003
H40.0 Glaucoma suspect	0.003	0.997	0.000
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.003
Y84.1 Kidney dialysis	0.000	0.997	0.003
M05 Seropositive rheumatoid arthritis	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
E06 Thyroiditis	0.000	0.997	0.003
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.997	0.003
D84 Other immunodeficiencies	0.003	0.997	0.000
T20.1 Burn of first degree of head and neck	0.000	0.997	0.003
M10.98 Gout, unspecified (Other)	0.003	0.997	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M10.91 Gout, unspecified (Shoulder region)	0.003	0.997	0.000
D32.0 Cerebral meninges	0.003	0.997	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.997	0.003
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.997	0.003
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
Y84.0 Cardiac catheterisation	0.000	0.997	0.003
H80-H83 Diseases of inner ear	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.000	0.997	0.003
E14.9 Without complications	0.000	0.997	0.003
T21.3 Burn of third degree of trunk	0.000	0.997	0.003
T21.0 Burn of unspecified degree of trunk	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E00 Congenital iodine-deficiency syndrome	0.000	0.997	0.003
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.003
E28.8 Other ovarian dysfunction	0.000	0.997	0.003
E28.1 Androgen excess	0.000	0.997	0.003
E28.0 Oestrogen excess	0.000	0.997	0.003
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.003	0.997	0.000
Y84.3 Shock therapy	0.000	0.997	0.003
M10 Gout	0.003	0.997	0.000
T20.7 Corrosion of third degree of head and neck	0.000	0.997	0.003
T20.6 Corrosion of second degree of head and neck	0.000	0.997	0.003
T20.5 Corrosion of first degree of head and neck	0.000	0.997	0.003
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.997	0.003
T25.3 Burn of third degree of ankle and foot	0.000	0.997	0.003
T25.7 Corrosion of third degree of ankle and foot	0.000	0.997	0.003
T25.6 Corrosion of second degree of ankle and foot	0.000	0.997	0.003
T25.5 Corrosion of first degree of ankle and foot	0.000	0.997	0.003
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.997	0.003
T25.1 Burn of first degree of ankle and foot	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.997	0.003
M10.92 Gout, unspecified (Upper arm)	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
Y84.7 Blood-sampling	0.000	0.997	0.003
Y84.5 Insertion of gastric or duodenal sound	0.000	0.997	0.003
D84.1 Defects in the complement system	0.003	0.997	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.997	0.003
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.997	0.003
C62 Malignant neoplasm of testis	0.000	0.997	0.003
E04 Other non-toxic goitre	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.997	0.003
T20.3 Burn of third degree of head and neck	0.000	0.997	0.003
T20.2 Burn of second degree of head and neck	0.000	0.997	0.003
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T25.2 Burn of second degree of ankle and foot	0.000	0.997	0.003
M10.96 Gout, unspecified (Lower leg)	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.000	0.997	0.003
T21.6 Corrosion of second degree of trunk	0.000	0.997	0.003
T21.5 Corrosion of first degree of trunk	0.000	0.997	0.003
T21.4 Corrosion of unspecified degree of trunk	0.000	0.997	0.003
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.997	0.003
M05.0 Felty's syndrome	0.003	0.997	0.000
E07 Other disorders of thyroid	0.000	0.997	0.003
C62.1 Descended testis	0.000	0.997	0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.000	0.997	0.003
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T21.1 Burn of first degree of trunk	0.000	0.997	0.002
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
Y84.9 Medical procedure, unspecified	0.000	0.997	0.003
M10.07 Idiopathic gout (Ankle and foot)	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.002	0.997	0.000
H36.0 Diabetic retinopathy	0.000	0.997	0.003
M10.0 Idiopathic gout	0.003	0.997	0.000
E67.8 Other specified hyperalimentation	0.000	0.997	0.002
E67.3 Hypervitaminosis D	0.000	0.997	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.997	0.002
E67.1 Hypercarotenaemia	0.000	0.997	0.002
E67.0 Hypervitaminosis A	0.000	0.997	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.997	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.003	0.997	0.000
E06.4 Drug-induced thyroiditis	0.000	0.997	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.997	0.002
E06.0 Acute thyroiditis	0.000	0.997	0.002
M05.8 Other seropositive rheumatoid arthritis	0.002	0.997	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.002	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.997	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.997	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.997	0.002
E10.9 Without complications	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
M05.1 Rheumatoid lung disease	0.002	0.998	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.998	0.002
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.000	0.998	0.002
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.998	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.998	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.998	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.998	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.998	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.998	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.998	0.002
M10.09 Idiopathic gout (Site unspecified)	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
M10.3 Gout due to impairment of renal function	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
M10.4 Other secondary gout	0.002	0.998	0.000
M10.2 Drug-induced gout	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations