TreeWAS – Variant ID: rs1275922

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I10-I15 Hypertensive diseases	0.912	0.088	0.000
I12 Hypertensive renal disease	0.897	0.103	0.000
I12.0 Hypertensive renal disease with renal failure	0.862	0.138	0.000
I12.9 Hypertensive renal disease without renal failure	0.821	0.179	0.000
I13 Hypertensive heart and renal disease	0.654	0.346	0.000
I11 Hypertensive heart disease	0.643	0.357	0.000
I15 Secondary hypertension	0.608	0.392	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.504	0.495	0.000
I15.0 Renovascular hypertension	0.492	0.508	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.469	0.531	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.469	0.531	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.469	0.531	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.469	0.531	0.000
I15.8 Other secondary hypertension	0.436	0.564	0.000
I15.2 Hypertension secondary to endocrine disorders	0.436	0.564	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.390	0.610	0.000
I15.1 Hypertension secondary to other renal disorders	0.376	0.623	0.000
I15.9 Seconday hypertension, unspecified	0.368	0.631	0.000
N18.3 Chronic kidney disease, stage 3	0.066	0.934	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.936	0.064
N18 Chronic renal failure	0.057	0.943	0.000
N18.5 Chronic kidney disease, stage 5	0.055	0.945	0.000
N18.4 Chronic kidney disease, stage 4	0.049	0.951	0.000
N18.8 Other chronic renal failure	0.047	0.953	0.000
N18.0 End-stage renal disease	0.045	0.955	0.000
N18.1 Chronic kidney disease, stage 1	0.038	0.962	0.000
N18.9 Chronic renal failure, unspecified	0.034	0.966	0.000
N17-N19 Renal failure	0.029	0.971	0.000
N18.2 Chronic kidney disease, stage 2	0.027	0.973	0.000
N19 Unspecified renal failure	0.027	0.973	0.000
G20 Parkinson's disease	0.000	0.983	0.017
G20-G26 Extrapyramidal and movement disorders	0.000	0.985	0.015
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.985	0.015
G24 Dystonia	0.000	0.986	0.014
G25 Other extrapyramidal and movement disorders	0.000	0.986	0.014
Z91.6 Personal history of other physical trauma	0.013	0.987	0.000
O21.0 Mild hyperemesis gravidarum	0.012	0.988	0.000
G24.9 Dystonia, unspecified	0.000	0.988	0.012
G24.5 Blepharospasm	0.000	0.988	0.012
G24.8 Other dystonia	0.000	0.988	0.012
N17 Acute renal failure	0.011	0.989	0.000
G21 Secondary Parkinsonism	0.000	0.989	0.011
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.000	0.989	0.011
G22 Parkinsonism in diseases classified elsewhere	0.000	0.989	0.011
O21 Excessive vomiting in pregnancy	0.011	0.989	0.000
G23 Other degenerative diseases of basal ganglia	0.000	0.989	0.011
G24.4 Idiopathic orofacial dystonia	0.000	0.989	0.010
G24.2 Idiopathic nonfamilial dystonia	0.000	0.989	0.010
G24.1 Idiopathic familial dystonia	0.000	0.989	0.010
G24.0 Drug-induced dystonia	0.000	0.989	0.010
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.989	0.011
G24.3 Spasmodic torticollis	0.000	0.989	0.010
G25.1 Drug-induced tremor	0.000	0.990	0.010
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.990	0.010
G25.5 Other chorea	0.000	0.990	0.010
G25.4 Drug-induced chorea	0.000	0.990	0.010
Z91.5 Personal history of self-harm	0.010	0.990	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.010	0.990	0.000
I99 Other and unspecified disorders of circulatory system	0.009	0.991	0.000
O21.2 Late vomiting of pregnancy	0.009	0.991	0.000
G25.2 Other specified forms of tremor	0.000	0.991	0.009
M19.90 Arthrosis, unspecified (Multiple sites)	0.009	0.991	0.000
O21.9 Vomiting of pregnancy, unspecified	0.009	0.991	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.009	0.991	0.000
N17.2 Acute renal failure with medullary necrosis	0.008	0.992	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.008	0.992	0.000
G21.9 Secondary Parkinsonism, unspecified	0.000	0.992	0.008
G21.8 Other secondary Parkinsonism	0.000	0.992	0.008
G21.4 Vascular parkinsonism	0.000	0.992	0.008
G21.3 Postencephalitic Parkinsonism	0.000	0.992	0.008
G21.2 Secondary Parkinsonism due to other external agents	0.000	0.992	0.008
G21.1 Other drug-induced secondary Parkinsonism	0.000	0.992	0.008
G21.0 Malignant neuroleptic syndrome	0.000	0.992	0.008
G23.9 Degenerative disease of basal ganglia, unspecified	0.000	0.992	0.008
G23.3 Multiple system atrophy, cerebellar type	0.000	0.992	0.008
G23.2 Striatonigral degeneration	0.000	0.992	0.008
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.000	0.992	0.008
G23.0 Hallervorden-Spatz disease	0.000	0.992	0.008
G82.5 Tetraplegia, unspecified	0.000	0.992	0.008
O21.8 Other vomiting complicating pregnancy	0.008	0.992	0.000
G25.0 Essential tremor	0.000	0.992	0.008
N17.8 Other acute renal failure	0.008	0.992	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.000	0.992	0.008
N17.0 Acute renal failure with tubular necrosis	0.008	0.992	0.000
Z91.2 Personal history of poor personal hygiene	0.007	0.992	0.000
G82 Paraplegia and tetraplegia	0.000	0.993	0.007
O20-O29 Other maternal disorders predominantly related to pregnancy	0.007	0.993	0.000
G25.3 Myoclonus	0.000	0.993	0.007
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.007	0.993	0.000
G82.2 Paraplegia, unspecified	0.000	0.993	0.007
O23 Infections of genito-urinary tract in pregnancy	0.007	0.993	0.000
G82.4 Spastic tetraplegia	0.000	0.993	0.007
O26.9 Pregnancy-related condition, unspecified	0.007	0.993	0.000
G82.1 Spastic paraplegia	0.000	0.994	0.006
Z49.1 Extracorporeal dialysis	0.006	0.994	0.000
Z91.7 Personal history of female genital mutilation	0.006	0.994	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.006	0.994	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.006	0.994	0.000
O23.5 Infections of the genital tract in pregnancy	0.006	0.994	0.000
O22 Venous complications in pregnancy	0.006	0.994	0.000
O24 Diabetes mellitus in pregnancy	0.006	0.994	0.000
Chapter IX Diseases of the circulatory system	0.006	0.994	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.006	0.994	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.006	0.994	0.000
Z49.2 Other dialysis	0.006	0.994	0.000
Z49 Care involving dialysis	0.006	0.994	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.006	0.994	0.000
Z49.0 Preparatory care for dialysis	0.006	0.994	0.000
G82.3 Flaccid tetraplegia	0.000	0.994	0.005
G82.0 Flaccid paraplegia	0.000	0.994	0.005
I35.1 Aortic (valve) insufficiency	0.006	0.994	0.000
O29 Complications of anaesthesia during pregnancy	0.005	0.994	0.000
O25 Malnutrition in pregnancy	0.005	0.994	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.005	0.995	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.005	0.995	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.005	0.995	0.000
O23.2 Infections of urethra in pregnancy	0.005	0.995	0.000
O23.1 Infections of bladder in pregnancy	0.005	0.995	0.000
O23.0 Infections of kidney in pregnancy	0.005	0.995	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.005	0.995	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.005	0.995	0.000
O22.1 Genital varices in pregnancy	0.005	0.995	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.005	0.995	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.005	0.995	0.000
O22.9 Venous complication in pregnancy, unspecified	0.005	0.995	0.000
O22.8 Other venous complications in pregnancy	0.005	0.995	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.005	0.995	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.005	0.995	0.000
I00-I02 Acute rheumatic fever	0.005	0.995	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.995	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.005	0.995	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.005	0.995	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.005	0.995	0.000
K04.7 Periapical abscess without sinus	0.000	0.995	0.005
O22.4 Haemorrhoids in pregnancy	0.005	0.995	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.005	0.995	0.000
O26.0 Excessive weight gain in pregnancy	0.004	0.995	0.000
I37.1 Pulmonary valve insufficiency	0.005	0.995	0.000
O26.5 Maternal hypotension syndrome	0.004	0.995	0.000
O26.4 Herpes gestationis	0.004	0.995	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.004	0.995	0.000
O26.1 Low weight gain in pregnancy	0.004	0.995	0.000
K04.5 Chronic apical periodontitis	0.000	0.995	0.005
I27 Other pulmonary heart diseases	0.005	0.995	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.004	0.995	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.004	0.995	0.000
I28 Other diseases of pulmonary vessels	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.004	0.996	0.000
I97.1 Other functional disturbances following cardiac surgery	0.004	0.996	0.000
I45.1 Other and unspecified right bundle-branch block	0.004	0.996	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.004	0.996	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.6 Failed or difficult intubation during pregnancy	0.004	0.996	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.004	0.996	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.004	0.996	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.004	0.996	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.004	0.996	0.000
K22.4 Dyskinesia of oesophagus	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
I97.0 Postcardiotomy syndrome	0.004	0.996	0.000
O26.8 Other specified pregnancy-related conditions	0.004	0.996	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.004	0.996	0.000
S12.1 Fracture of second cervical vertebra	0.004	0.996	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.004	0.996	0.000
F52.2 Failure of genital response	0.000	0.996	0.004
I00 Rheumatic fever without mention of heart involvement	0.004	0.996	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
I37 Pulmonary valve disorders	0.004	0.996	0.000
I27.2 Other secondary pulmonary hypertension	0.004	0.996	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.004	0.996	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.004	0.996	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.004	0.996	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.004	0.996	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.004	0.996	0.000
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.003	0.996	0.000
I02 Rheumatic chorea	0.003	0.996	0.000
I01 Rheumatic fever with heart involvement	0.003	0.996	0.000
I28.8 Other specified diseases of pulmonary vessels	0.004	0.996	0.000
R15 Faecal incontinence	0.000	0.996	0.004
S12 Fracture of neck	0.004	0.996	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.003	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.996	0.000
I44.3 Other and unspecified atrioventricular block	0.004	0.996	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.003	0.996	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.003	0.997	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.003	0.997	0.000
I28.1 Aneurysm of pulmonary artery	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.003	0.997	0.000
S12.0 Fracture of first cervical vertebra	0.003	0.997	0.000
I42 Cardiomyopathy	0.003	0.997	0.000
I35 Nonrheumatic aortic valve disorders	0.003	0.997	0.000
I44 Atrioventricular and left bundle-branch block	0.003	0.997	0.000
O26.2 Pregnancy care of habitual aborter	0.003	0.997	0.000
S12.2 Fracture of other specified cervical vertebra	0.003	0.997	0.000
I45 Other conduction disorders	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
I37.0 Pulmonary valve stenosis	0.003	0.997	0.000
S12.11 Fracture of second cervical vertebra (open)	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.997	0.003
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
I44.4 Left anterior fascicular block	0.003	0.997	0.000
O62.3 Precipitate labour	0.003	0.997	0.000
R47.0 Dysphasia and aphasia	0.000	0.997	0.003
I30-I52 Other forms of heart disease	0.003	0.997	0.000
I45.9 Conduction disorder, unspecified	0.003	0.997	0.000
O62.2 Other uterine inertia	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
I37.9 Pulmonary valve disorder, unspecified	0.003	0.997	0.000
I37.8 Other pulmonary valve disorders	0.003	0.997	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.003	0.997	0.000
U80.0 Penicillin resistant agent	0.003	0.997	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.003	0.997	0.000
I01.8 Other acute rheumatic heart disease	0.003	0.997	0.000
I01.2 Acute rheumatic myocarditis	0.003	0.997	0.000
I01.1 Acute rheumatic endocarditis	0.003	0.997	0.000
I01.0 Acute rheumatic pericarditis	0.003	0.997	0.000
I02.9 Rheumatic chorea without heart involvement	0.003	0.997	0.000
I02.0 Rheumatic chorea with heart involvement	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
I44.0 Atrioventricular block, first degree	0.003	0.997	0.000
I45.0 Right fascicular block	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
S12.9 Fracture of neck, part unspecified	0.003	0.997	0.000
S12.8 Fracture of other parts of neck	0.003	0.997	0.000
S12.01 Fracture of first cervical vertebra (open)	0.003	0.997	0.000
I42.4 Endocardial fibroelastosis	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997	0.000
I06 Rheumatic aortic valve diseases	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.003	0.997	0.000
I44.5 Left posterior fascicular block	0.003	0.997	0.000
B35.3 Tinea pedis	0.000	0.997	0.003
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
I35.8 Other aortic valve disorders	0.003	0.997	0.000
I45.4 Nonspecific intraventricular block	0.003	0.997	0.000
S12.7 Multiple fractures of cervical spine	0.003	0.997	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.997	0.003
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.997	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
S10.9 Superficial injury of neck, part unspecified	0.003	0.997	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.997	0.000
I44.1 Atrioventricular block, second degree	0.003	0.997	0.000
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
I52 Other heart disorders in diseases classified elsewhere	0.002	0.997	0.000
I48 Atrial fibrillation and flutter	0.002	0.997	0.000
I41 Myocarditis in diseases classified elsewhere	0.002	0.997	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.002	0.997	0.000
I32 Pericarditis in diseases classified elsewhere	0.002	0.997	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.002	0.998	0.000
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
O62 Abnormalities of forces of labour	0.002	0.998	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.002	0.998	0.000
S12.81 Fracture of other parts of neck (open)	0.002	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.002	0.998	0.000
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.002	0.998	0.000
I45.5 Other specified heart block	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
N85.4 Malposition of uterus	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.000	0.998	0.002
I40 Acute myocarditis	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.002	0.998	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.002	0.998	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I98.0 Cardiovascular syphilis	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.998	0.002
I45.3 Trifascicular block	0.002	0.998	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.002	0.998	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.002	0.998	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.002	0.998	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.002	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.002	0.998	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.002	0.998	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.002	0.998	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.002	0.998	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.002	0.998	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.002	0.998	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.002	0.998	0.000
I48.4 Atypical atrial flutter	0.002	0.998	0.000
I48.3 Typical atrial flutter	0.002	0.998	0.000
I48.2 Chronic atrial fibrillation	0.002	0.998	0.000
I48.1 Persistent atrial fibrillation	0.002	0.998	0.000
I48.0 Paroxysmal atrial fibrillation	0.002	0.998	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.002	0.998	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.002	0.998	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.998	0.002
O62.1 Secondary uterine inertia	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.002	0.998	0.000
S10.0 Contusion of throat	0.002	0.998	0.000
S11.7 Multiple open wounds of neck	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
S11.9 Open wound of neck, part unspecified	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
I40.8 Other acute myocarditis	0.002	0.998	0.000
I40.1 Isolated myocarditis	0.002	0.998	0.000
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
K04.3 Abnormal hard tissue formation in pulp	0.000	0.998	0.002
K04.2 Pulp degeneration	0.000	0.998	0.002
K04.1 Necrosis of pulp	0.000	0.998	0.002
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
I08 Multiple valve diseases	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
I40.9 Acute myocarditis, unspecified	0.002	0.998	0.000
I45.8 Other specified conduction disorders	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.998	0.002
I33 Acute and subacute endocarditis	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
N30.3 Trigonitis	0.000	0.998	0.002
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.002	0.998	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
I40.0 Infective myocarditis	0.001	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.001	0.998	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.998	0.000
K04.0 Pulpitis	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.998	0.002
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
I45.2 Bifascicular block	0.001	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.001	0.998	0.000
I30.1 Infective pericarditis	0.001	0.998	0.000
O62.0 Primary inadequate contractions	0.001	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.001	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.001	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.001	0.998	0.000
S15.3 Injury of internal jugular vein	0.001	0.998	0.000
S15.2 Injury of external jugular vein	0.001	0.998	0.000
S15.1 Injury of vertebral artery	0.001	0.998	0.000
S15.0 Injury of carotid artery	0.001	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.001	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.001	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.001	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.998	0.002
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.998	0.002
S19 Other and unspecified injuries of neck	0.002	0.998	0.000
N39.4 Other specified urinary incontinence	0.000	0.998	0.002
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.998	0.000
Q45.1 Annular pancreas	0.001	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.998	0.000
S13.3 Multiple dislocations of neck	0.001	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.998	0.000
W22.9 Unspecified place	0.000	0.998	0.002
I33.9 Acute endocarditis, unspecified	0.001	0.998	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.001	0.998	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.998	0.002
M95.3 Acquired deformity of neck	0.001	0.998	0.000
M96.5 Postradiation scoliosis	0.001	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
Z04.1 Examination and observation following transport accident	0.002	0.998	0.000
I20.8 Other forms of angina pectoris	0.000	0.998	0.002
G90 Disorders of autonomic nervous system	0.000	0.998	0.002
I07.9 Tricuspid valve disease, unspecified	0.001	0.998	0.000
I07.8 Other tricuspid valve diseases	0.001	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.998	0.000
I07.0 Tricuspid stenosis	0.001	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.001	0.998	0.000
Q44.6 Cystic disease of liver	0.001	0.998	0.000
R26.3 Immobility	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.001
M86.96 Osteomyelitis, unspecified (Lower leg)	0.001	0.998	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.001
G04.1 Tropical spastic paraplegia	0.000	0.998	0.001
G04.0 Acute disseminated encephalitis	0.000	0.998	0.001
K75.4 Autoimmune hepatitis	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations