TreeWAS – Variant ID: rs12883384

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69 Sequelae of cerebrovascular disease	0.000	0.757	0.243
I67.9 Cerebrovascular disease, unspecified	0.000	0.759	0.241
I60-I69 Cerebrovascular diseases	0.000	0.762	0.238
I67 Other cerebrovascular diseases	0.000	0.763	0.237
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.765	0.235
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.772	0.228
I62 Other nontraumatic intracranial haemorrhage	0.000	0.777	0.223
I60 Subarachnoid haemorrhage	0.000	0.790	0.210
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.790	0.210
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.795	0.205
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.798	0.202
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.800	0.200
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.809	0.190
I62.1 Nontraumatic extradural haemorrhage	0.000	0.811	0.189
I61 Intracerebral haemorrhage	0.000	0.812	0.188
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.812	0.188
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.812	0.188
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.822	0.178
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.825	0.175
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.829	0.171
I67.5 Moyamoya disease	0.000	0.830	0.170
I67.4 Hypertensive encephalopathy	0.000	0.830	0.170
I67.3 Progressive vascular leukoencephalopathy	0.000	0.830	0.170
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.831	0.169
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.837	0.163
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.837	0.163
I67.2 Cerebral atherosclerosis	0.000	0.838	0.162
I69.3 Sequelae of cerebral infarction	0.000	0.838	0.162
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.839	0.161
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.843	0.157
I68.0 Cerebral amyloid angiopathy	0.000	0.844	0.156
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.847	0.153
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.849	0.151
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.852	0.148
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.852	0.148
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.855	0.145
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.857	0.143
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.860	0.140
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.860	0.139
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.863	0.137
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.863	0.137
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.863	0.137
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.863	0.137
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.866	0.134
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.867	0.133
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.869	0.131
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.870	0.130
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.873	0.127
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.874	0.126
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.877	0.123
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.877	0.123
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.877	0.123
I65.1 Occlusion and stenosis of basilar artery	0.000	0.882	0.118
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.882	0.117
I77 Other disorders of arteries and arterioles	0.000	0.882	0.118
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.884	0.116
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.885	0.115
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.887	0.112
I72 Other aneurysm	0.000	0.888	0.112
I77.1 Stricture of artery	0.000	0.888	0.112
I67.1 Cerebral aneurysm, nonruptured	0.000	0.889	0.111
I72.9 Aneurysm of unspecified site	0.000	0.894	0.106
I73 Other peripheral vascular diseases	0.000	0.895	0.105
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.896	0.104
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.896	0.104
I77.6 Arteritis, unspecified	0.000	0.897	0.103
I73.9 Peripheral vascular disease, unspecified	0.000	0.898	0.102
I72.0 Aneurysm of carotid artery	0.000	0.898	0.102
Chapter IX Diseases of the circulatory system	0.000	0.900	0.100
I77.0 Arteriovenous fistula, acquired	0.000	0.900	0.100
I67.8 Other specified cerebrovascular diseases	0.000	0.901	0.099
I65.2 Occlusion and stenosis of carotid artery	0.000	0.902	0.098
I61.8 Other intracerebral haemorrhage	0.000	0.902	0.097
I74 Arterial embolism and thrombosis	0.000	0.904	0.096
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.907	0.093
I60.8 Other subarachnoid haemorrhage	0.000	0.907	0.092
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.908	0.092
I77.2 Rupture of artery	0.000	0.910	0.090
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.911	0.089
I72.3 Aneurysm of iliac artery	0.000	0.912	0.088
I27 Other pulmonary heart diseases	0.000	0.912	0.088
I72.8 Aneurysm of other specified arteries	0.000	0.912	0.088
I77.3 Arterial fibromuscular dysplasia	0.000	0.914	0.086
I77.5 Necrosis of artery	0.000	0.915	0.084
I77.4 Coeliac artery compression syndrome	0.000	0.915	0.084
I77.8 Other specified disorders of arteries and arterioles	0.000	0.917	0.083
I73.0 Raynaud's syndrome	0.000	0.918	0.082
I72.2 Aneurysm of renal artery	0.000	0.918	0.082
I70 Atherosclerosis	0.000	0.918	0.082
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.919	0.081
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.919	0.081
I27.2 Other secondary pulmonary hypertension	0.000	0.920	0.080
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.920	0.080
I27.0 Primary pulmonary hypertension	0.000	0.920	0.080
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.922	0.078
I74.8 Embolism and thrombosis of other arteries	0.000	0.923	0.077
I72.1 Aneurysm of artery of upper extremity	0.000	0.923	0.077
I27.8 Other specified pulmonary heart diseases	0.000	0.923	0.077
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.926	0.074
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.927	0.073
L40.5 Arthropathic psoriasis	0.000	0.928	0.072
I10-I15 Hypertensive diseases	0.000	0.930	0.070
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.931	0.069
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.931	0.069
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.931	0.069
I00-I02 Acute rheumatic fever	0.000	0.935	0.065
I27.1 Kyphoscoliotic heart disease	0.000	0.937	0.063
I70.9 Generalised and unspecified atherosclerosis	0.000	0.938	0.062
I70.0 Atherosclerosis of aorta	0.000	0.940	0.060
I70.1 Atherosclerosis of renal artery	0.000	0.940	0.060
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.941	0.059
I15 Secondary hypertension	0.000	0.941	0.059
I11 Hypertensive heart disease	0.000	0.942	0.058
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.942	0.058
I13 Hypertensive heart and renal disease	0.000	0.943	0.057
I72.4 Aneurysm of artery of lower extremity	0.000	0.943	0.057
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.945	0.055
I28 Other diseases of pulmonary vessels	0.000	0.945	0.054
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.945	0.054
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.946	0.054
I79.1 Aortitis in diseases classified elsewhere	0.000	0.947	0.053
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.947	0.053
I70.8 Atherosclerosis of other arteries	0.000	0.947	0.053
I73.8 Other specified peripheral vascular diseases	0.000	0.947	0.053
I15.1 Hypertension secondary to other renal disorders	0.000	0.951	0.049
I27.9 Pulmonary heart disease, unspecified	0.000	0.952	0.048
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.952	0.048
I15.0 Renovascular hypertension	0.000	0.952	0.048
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.952	0.047
I02 Rheumatic chorea	0.000	0.953	0.047
I01 Rheumatic fever with heart involvement	0.000	0.953	0.047
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.953	0.047
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.953	0.047
I20-I25 Ischaemic heart diseases	0.000	0.954	0.046
I78 Diseases of capillaries	0.000	0.954	0.046
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.955	0.045
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.955	0.045
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.955	0.044
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.956	0.044
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.956	0.044
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.957	0.043
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.957	0.043
I15.8 Other secondary hypertension	0.000	0.957	0.043
I15.2 Hypertension secondary to endocrine disorders	0.000	0.957	0.043
I22 Subsequent myocardial infarction	0.000	0.958	0.042
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.958	0.041
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.959	0.041
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.959	0.041
I15.9 Seconday hypertension, unspecified	0.000	0.959	0.040
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.960	0.040
I00 Rheumatic fever without mention of heart involvement	0.000	0.960	0.040
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.960	0.040
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.961	0.039
I28.1 Aneurysm of pulmonary artery	0.000	0.961	0.039
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.961	0.039
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.961	0.039
I05-I09 Chronic rheumatic heart diseases	0.000	0.962	0.038
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.962	0.038
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.962	0.038
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.962	0.038
I26 Pulmonary embolism	0.000	0.962	0.038
I24 Other acute ischaemic heart diseases	0.000	0.963	0.037
S06.8 Other intracranial injuries	0.000	0.963	0.037
I74.5 Embolism and thrombosis of iliac artery	0.000	0.963	0.037
S06 Intracranial injury	0.000	0.964	0.036
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.964	0.036
S06.3 Focal brain injury	0.000	0.965	0.035
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.965	0.035
S06.0 Concussion	0.000	0.966	0.034
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.966	0.034
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.966	0.034
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.966	0.034
I01.8 Other acute rheumatic heart disease	0.000	0.966	0.034
I01.2 Acute rheumatic myocarditis	0.000	0.966	0.034
I01.1 Acute rheumatic endocarditis	0.000	0.966	0.034
I01.0 Acute rheumatic pericarditis	0.000	0.966	0.034
I02.9 Rheumatic chorea without heart involvement	0.000	0.966	0.034
I02.0 Rheumatic chorea with heart involvement	0.000	0.966	0.034
S06.00 Concussion (without open intracranial wound)	0.000	0.967	0.033
I23 Certain current complications following acute myocardial infarction	0.000	0.967	0.033
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.968	0.032
I78.9 Disease of capillaries, unspecified	0.000	0.968	0.032
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.968	0.032
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.969	0.031
L92.0 Granuloma annulare	0.000	0.969	0.031
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.969	0.031
I07 Rheumatic tricuspid valve diseases	0.000	0.969	0.030
I28.8 Other specified diseases of pulmonary vessels	0.000	0.970	0.029
I06 Rheumatic aortic valve diseases	0.000	0.970	0.030
I20 Angina pectoris	0.000	0.970	0.030
I10 Essential (primary) hypertension	0.000	0.971	0.029
S06.4 Epidural haemorrhage	0.000	0.971	0.029
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.971	0.029
I78.8 Other diseases of capillaries	0.000	0.972	0.028
I12 Hypertensive renal disease	0.000	0.972	0.028
S06.9 Intracranial injury, unspecified	0.000	0.973	0.027
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.973	0.027
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.973	0.027
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.973	0.026
S06.5 Traumatic subdural haemorrhage	0.000	0.973	0.026
S06.7 Intracranial injury with prolonged coma	0.000	0.974	0.026
I20.0 Unstable angina	0.000	0.974	0.026
I24.1 Dressler's syndrome	0.000	0.974	0.026
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.974	0.025
S06.2 Diffuse brain injury	0.000	0.975	0.025
I06.0 Rheumatic aortic stenosis	0.000	0.975	0.025
S06.1 Traumatic cerebral oedema	0.000	0.975	0.025
S06.01 Concussion (with open intracranial wound)	0.000	0.975	0.025
I09 Other rheumatic heart diseases	0.000	0.975	0.025
I07.1 Tricuspid insufficiency	0.000	0.975	0.025
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.975	0.024
I22.8 Subsequent myocardial infarction of other sites	0.000	0.976	0.024
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.976	0.024
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.976	0.024
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.976	0.024
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.976	0.024
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.976	0.024
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.976	0.024
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.976	0.024
I23.8 Other current complications following acute myocardial infarction	0.000	0.976	0.024
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.977	0.022
M65.8 Other synovitis and tenosynovitis	0.000	0.977	0.023
I07.9 Tricuspid valve disease, unspecified	0.000	0.978	0.022
I07.8 Other tricuspid valve diseases	0.000	0.978	0.022
I07.2 Tricuspid stenosis with insufficiency	0.000	0.978	0.022
I07.0 Tricuspid stenosis	0.000	0.978	0.022
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.000	0.978	0.022
M65 Synovitis and tenosynovitis	0.000	0.978	0.022
I20.1 Angina pectoris with documented spasm	0.000	0.978	0.022
I20.8 Other forms of angina pectoris	0.000	0.978	0.022
M65.3 Trigger finger	0.000	0.978	0.022
I06.8 Other rheumatic aortic valve diseases	0.000	0.978	0.021
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.978	0.021
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.978	0.022
I78.1 Naevus, nonneoplastic	0.000	0.979	0.021
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.979	0.021
M65.34 Trigger finger-Hand	0.000	0.979	0.021
I63 Cerebral infarction	0.000	0.979	0.021
M65.1 Other infective (teno)synovitis	0.000	0.979	0.021
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.979	0.021
M65.14 Other infective (teno)synovitis (Hand)	0.000	0.979	0.021
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.980	0.020
I24.8 Other forms of acute ischaemic heart disease	0.000	0.980	0.020
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.980	0.020
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.980	0.020
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.980	0.020
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.980	0.019
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.981	0.019
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.981	0.019
M07.3 Other psoriatic arthropathies	0.000	0.981	0.019
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.981	0.019
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.981	0.019
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.981	0.019
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.981	0.019
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.981	0.018
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.982	0.018
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.000	0.982	0.018
I09.8 Other specified rheumatic heart diseases	0.000	0.982	0.018
I09.2 Chronic rheumatic pericarditis	0.000	0.982	0.018
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.982	0.018
I09.0 Rheumatic myocarditis	0.000	0.982	0.018
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.982	0.018
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.982	0.018
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.982	0.018
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.983	0.017
I05 Rheumatic mitral valve diseases	0.000	0.983	0.017
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.983	0.017
M65.39 Trigger finger-Site unspec	0.000	0.983	0.017
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.983	0.017
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.000	0.984	0.016
M65.88 Other synovitis and tenosynovitis (Other)	0.000	0.984	0.016
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.000	0.984	0.016
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.000	0.984	0.016
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.000	0.984	0.016
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.984	0.016
I06.1 Rheumatic aortic insufficiency	0.000	0.984	0.016
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.984	0.016
M65.38 Trigger finger-Other	0.000	0.984	0.016
M65.37 Trigger finger-Ankle/foot	0.000	0.984	0.016
M65.36 Trigger finger-Lower leg	0.000	0.984	0.016
M65.35 Trigger finger-Pelvic/thigh	0.000	0.984	0.016
M65.33 Trigger finger-Forearm	0.000	0.984	0.016
M65.32 Trigger finger-Upper arm	0.000	0.984	0.016
M65.31 Trigger finger-Shldr region	0.000	0.984	0.016
M65.30 Trigger finger-Mult sites	0.000	0.984	0.016
M65.0 Abscess of tendon sheath	0.000	0.984	0.016
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.985	0.015
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.985	0.015
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.985	0.015
M65.19 Other infective (teno)synovitis (Site unspecified)	0.000	0.985	0.015
M65.18 Other infective (teno)synovitis (Other)	0.000	0.985	0.015
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.000	0.985	0.015
M65.16 Other infective (teno)synovitis (Lower leg)	0.000	0.985	0.015
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.000	0.985	0.015
M65.13 Other infective (teno)synovitis (Forearm)	0.000	0.985	0.015
M65.12 Other infective (teno)synovitis (Upper arm)	0.000	0.985	0.015
M65.11 Other infective (teno)synovitis (Shoulder region)	0.000	0.985	0.015
M65.10 Other infective (teno)synovitis (Multiple sites)	0.000	0.985	0.015
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.985	0.015
I71 Aortic aneurysm and dissection	0.000	0.985	0.015
I09.9 Rheumatic heart disease, unspecified	0.000	0.985	0.015
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.985	0.015
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.985	0.014
L91.0 Keloid scar	0.000	0.986	0.014
M65.2 Calcific tendinitis	0.000	0.986	0.014
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.986	0.014
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.000	0.986	0.014
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.000	0.986	0.014
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.000	0.986	0.014
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.000	0.986	0.014
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.000	0.986	0.014
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.000	0.986	0.014
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.000	0.986	0.014
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.000	0.986	0.014
M07.38 Other psoriatic arthropathies (Other)	0.000	0.986	0.014
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.986	0.014
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.986	0.014
O42.9 Premature rupture of membranes, unspecified	0.014	0.986	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.986	0.014
I12.0 Hypertensive renal disease with renal failure	0.000	0.987	0.013
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.987	0.013
M65-M68 Disorders of synovium and tendon	0.000	0.987	0.013
I05.0 Mitral stenosis	0.000	0.987	0.013
L91 Hypertrophic disorders of skin	0.000	0.987	0.013
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.987	0.012
L95 Vasculitis limited to skin, not elsewhere classified	0.000	0.988	0.012
L83 Acanthosis nigricans	0.000	0.988	0.012
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.988	0.012
L95.9 Vasculitis limited to skin, unspecified	0.000	0.988	0.012
M07 Psoriatic and enteropathic arthropathies	0.000	0.988	0.012
I05.8 Other mitral valve diseases	0.000	0.988	0.012
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.988	0.012
I05.9 Mitral valve disease, unspecified	0.000	0.988	0.012
I05.1 Rheumatic mitral insufficiency	0.000	0.988	0.012
I63.8 Other cerebral infarction	0.000	0.988	0.011
M65.09 Abscess of tendon sheath (Site unspecified)	0.000	0.988	0.011
M65.08 Abscess of tendon sheath (Other)	0.000	0.988	0.011
M65.07 Abscess of tendon sheath (Ankle and foot)	0.000	0.988	0.011
M65.06 Abscess of tendon sheath (Lower leg)	0.000	0.988	0.011
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.000	0.988	0.011
M65.03 Abscess of tendon sheath (Forearm)	0.000	0.988	0.011
M65.02 Abscess of tendon sheath (Upper arm)	0.000	0.988	0.011
M65.01 Abscess of tendon sheath (Shoulder region)	0.000	0.988	0.011
M65.00 Abscess of tendon sheath (Multiple sites)	0.000	0.988	0.011
M54.37 Sciatica (Lumbosacral region)	0.000	0.988	0.012
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.989	0.011
L94 Other localised connective tissue disorders	0.000	0.989	0.011
M65.04 Abscess of tendon sheath (Hand)	0.000	0.989	0.011
I12.9 Hypertensive renal disease without renal failure	0.000	0.989	0.011
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.989	0.011
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.989	0.011
L80 Vitiligo	0.000	0.989	0.011
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.989	0.011
M67 Other disorders of synovium and tendon	0.000	0.989	0.011
L40 Psoriasis	0.000	0.989	0.011
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.989	0.011
M65.29 Calcific tendinitis (Site unspecified)	0.000	0.990	0.010
M65.28 Calcific tendinitis (Other)	0.000	0.990	0.010
M65.27 Calcific tendinitis (Ankle and foot)	0.000	0.990	0.010
M65.26 Calcific tendinitis (Lower leg)	0.000	0.990	0.010
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.000	0.990	0.010
M65.24 Calcific tendinitis (Hand)	0.000	0.990	0.010
M65.23 Calcific tendinitis (Forearm)	0.000	0.990	0.010
M65.22 Calcific tendinitis (Upper arm)	0.000	0.990	0.010
M65.20 Calcific tendinitis (Multiple sites)	0.000	0.990	0.010
L87 Transepidermal elimination disorders	0.000	0.990	0.010
L86 Keratoderma in diseases classified elsewhere	0.000	0.990	0.010
L82 Seborrhoeic keratosis	0.000	0.990	0.010
I08 Multiple valve diseases	0.000	0.990	0.010
L93 Lupus erythematosus	0.000	0.990	0.010
L89 Decubitus ulcer	0.000	0.990	0.010
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.990	0.010
M11.2 Other chondrocalcinosis	0.000	0.990	0.010
L90 Atrophic disorders of skin	0.000	0.990	0.010
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.990	0.010
L89.2 Stage III decubitus ulcer	0.000	0.990	0.010
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.990	0.010
L81 Other disorders of pigmentation	0.000	0.990	0.010
L88 Pyoderma gangrenosum	0.000	0.990	0.010
L94.9 Localised connective tissue disorder, unspecified	0.000	0.990	0.010
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.000	0.990	0.010
M54.3 Sciatica	0.000	0.990	0.010
I08.8 Other multiple valve diseases	0.000	0.990	0.010
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.990	0.009
L81.9 Disorder of pigmentation, unspecified	0.000	0.991	0.009
M66 Spontaneous rupture of synovium and tendon	0.000	0.991	0.009
L91.9 Hypertrophic disorder of skin, unspecified	0.000	0.991	0.009
M54.6 Pain in thoracic spine	0.000	0.991	0.009
L95.1 Erythema elevatum diutinum	0.000	0.991	0.009
L95.0 Livedoid vasculitis	0.000	0.991	0.009
A87.9 Viral meningitis, unspecified	0.000	0.991	0.009
M67.0 Short Achilles tendon (acquired)	0.000	0.991	0.009
M67.1 Other contracture of tendon (sheath)	0.000	0.991	0.009
M07.6 Other enteropathic arthropathies	0.000	0.991	0.009
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.991	0.009
L90.5 Scar conditions and fibrosis of skin	0.000	0.991	0.009
M07.5 Arthropathy in ulcerative colitis	0.000	0.991	0.009
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.991	0.009
M07.2 Psoriatic spondylitis	0.000	0.991	0.009
M07.1 Arthritis mutilans	0.000	0.991	0.009
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.991	0.009
M65.21 Calcific tendinitis (Shoulder region)	0.000	0.991	0.008
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.991	0.008
I05.2 Mitral stenosis with insufficiency	0.000	0.992	0.008
G82.2 Paraplegia, unspecified	0.000	0.992	0.008
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.992	0.008
L73.9 Follicular disorder, unspecified	0.000	0.992	0.008
L94.8 Other specified localised connective tissue disorders	0.000	0.992	0.008
M54 Dorsalgia	0.000	0.992	0.008
L94.6 Ainhum	0.000	0.992	0.008
L94.5 Poikiloderma vasculare atrophicans	0.000	0.992	0.008
L94.4 Gottron's papules	0.000	0.992	0.008
L94.3 Sclerodactyly	0.000	0.992	0.008
L94.1 Linear scleroderma	0.000	0.992	0.008
I21 Acute myocardial infarction	0.000	0.992	0.008
L94.2 Calcinosis cutis	0.000	0.992	0.008
J34.1 Cyst and mucocele of nose and nasal sinus	0.000	0.992	0.008
L93.2 Other local lupus erythematosus	0.000	0.992	0.008
M66.3 Spontaneous rupture of flexor tendons	0.000	0.992	0.008
L89.1 Stage II decubitus ulcer	0.000	0.992	0.008
L40.0 Psoriasis vulgaris	0.000	0.992	0.008
M54.30 Sciatica (Multiple sites in spine)	0.000	0.992	0.008
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.992	0.008
M67.3 Transient synovitis	0.000	0.992	0.008
L40.2 Acrodermatitis continua	0.000	0.992	0.008
M11 Other crystal arthropathies	0.000	0.992	0.008
L40.1 Generalised pustular psoriasis	0.000	0.992	0.008
L87.9 Transepidermal elimination disorder, unspecified	0.000	0.992	0.008
L87.8 Other transepidermal elimination disorders	0.000	0.992	0.008
L87.2 Elastosis perforans serpiginosa	0.000	0.992	0.008
L87.1 Reactive perforating collagenosis	0.000	0.992	0.008
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.000	0.992	0.008
L93.1 Subacute cutaneous lupus erythematosus	0.000	0.992	0.008
M66.4 Spontaneous rupture of other tendons	0.000	0.992	0.008
M54.8 Other dorsalgia	0.000	0.992	0.008
T45.0 Antiallergic and antiemetic drugs	0.000	0.992	0.008
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.992	0.008
G82 Paraplegia and tetraplegia	0.000	0.992	0.008
L90.9 Atrophic disorder of skin, unspecified	0.000	0.992	0.007
M67.8 Other specified disorders of synovium and tendon	0.000	0.992	0.008
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.993	0.007
M11.28 Other chondrocalcinosis (Other)	0.000	0.993	0.007
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.993	0.007
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.993	0.007
M11.24 Other chondrocalcinosis (Hand)	0.000	0.993	0.007
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.993	0.007
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.993	0.007
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.993	0.007
L90.6 Striae atrophicae	0.000	0.993	0.007
L90.4 Acrodermatitis chronica atrophicans	0.000	0.993	0.007
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.993	0.007
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.993	0.007
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.993	0.007
L95.8 Other vasculitis limited to skin	0.000	0.993	0.007
L99.0 Amyloidosis of skin	0.000	0.993	0.007
I08.9 Multiple valve disease, unspecified	0.000	0.993	0.007
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.993	0.007
L73 Other follicular disorders	0.000	0.993	0.007
L94.0 Localised scleroderma [morphea]	0.000	0.993	0.007
L81.6 Other disorders of diminished melanin formation	0.000	0.993	0.007
L81.5 Leukoderma, not elsewhere classified	0.000	0.993	0.007
L81.3 Cafe au lait spots	0.000	0.993	0.007
L81.1 Chloasma	0.000	0.993	0.007
M54.9 Dorsalgia, unspecified	0.000	0.993	0.007
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.000	0.993	0.007
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.000	0.993	0.007
M54.35 Sciatica (Thoracolumbar region)	0.000	0.993	0.007
M54.34 Sciatica-Thoracic	0.000	0.993	0.007
M54.33 Sciatica-Cervicothoracic	0.000	0.993	0.007
M54.32 Sciatica-Cervical	0.000	0.993	0.007
M54.31 Sciatica-Occipit-atl-axl	0.000	0.993	0.007
L40.4 Guttate psoriasis	0.000	0.993	0.007
L81.0 Postinflammatory hyperpigmentation	0.000	0.993	0.007
M54.84 Other dorsalgia (Thoracic region)	0.000	0.993	0.007
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.000	0.993	0.007
G82.5 Tetraplegia, unspecified	0.000	0.993	0.007
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.993	0.007
M66.1 Rupture of synovium	0.000	0.993	0.007
L81.7 Pigmented purpuric dermatosis	0.000	0.993	0.007
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.993	0.007
L73.8 Other specified follicular disorders	0.000	0.993	0.007
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.000	0.993	0.007
M54.69 Pain in thoracic spine-Site unspe	0.000	0.993	0.007
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.000	0.993	0.007
M54.67 Pain in thoracic spine-Lumbosacral	0.000	0.993	0.007
M54.66 Pain in thoracic spine-Lumbar	0.000	0.993	0.007
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.000	0.993	0.007
M54.62 Pain in thoracic spine-Cervical	0.000	0.993	0.007
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.000	0.993	0.007
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.000	0.993	0.007
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.993	0.007
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.993	0.007
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.993	0.007
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.993	0.007
M54.89 Other dorsalgia (Site unspecified)	0.000	0.993	0.007
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.000	0.993	0.007
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.993	0.007
A87 Viral meningitis	0.000	0.993	0.007
M67.4 Ganglion	0.000	0.993	0.007
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.993	0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations