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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12953285
log Bayes Factor = 0.0020549
Chromosome 17   position 75,257,987  (GRCh37) Explore rs12953285 on Ensembl!
Variant rs12953285 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.000 0.991 0.009
D12.8 Rectum
0.000 0.992 0.008
D12.4 Descending colon
0.000 0.992 0.008
D12.5 Sigmoid colon
0.000 0.992 0.008
D12.6 Colon, unspecified
0.000 0.992 0.008
D12.3 Transverse colon
0.000 0.992 0.007
D12.0 Caecum
0.000 0.993 0.007
D12.7 Rectosigmoid junction
0.000 0.993 0.007
D12.1 Appendix
0.000 0.993 0.007
D12.9 Anus and anal canal
0.000 0.994 0.006
D12.2 Ascending colon
0.000 0.994 0.006
D10-D36 Benign neoplasms
0.000 0.995 0.005
D24 Benign neoplasm of breast
0.000 0.995 0.005
D27 Benign neoplasm of ovary
0.000 0.995 0.005
D32 Benign neoplasm of meninges
0.000 0.996 0.004
D23 Other benign neoplasms of skin
0.000 0.996 0.004
D34 Benign neoplasm of thyroid gland
0.000 0.996 0.004
D10 Benign neoplasm of mouth and pharynx
0.000 0.996 0.004
D11 Benign neoplasm of major salivary glands
0.000 0.996 0.004
D30 Benign neoplasm of urinary organs
0.000 0.996 0.004
D35 Benign neoplasm of other and unspecified endocrine glands
0.000 0.996 0.004
D22 Melanocytic naevi
0.000 0.996 0.004
D14 Benign neoplasm of middle ear and respiratory system
0.000 0.996 0.004
D26 Other benign neoplasms of uterus
0.000 0.996 0.004
D29 Benign neoplasm of male genital organs
0.000 0.996 0.004
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.000 0.996 0.004
D19 Benign neoplasm of mesothelial tissue
0.000 0.996 0.004
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.000 0.996 0.004
D21 Other benign neoplasms of connective and other soft tissue
0.000 0.996 0.004
D16 Benign neoplasm of bone and articular cartilage
0.000 0.996 0.004
D31 Benign neoplasm of eye and adnexa
0.000 0.996 0.004
D33 Benign neoplasm of brain and other parts of central nervous system
0.000 0.996 0.004
D23.3 Skin of other and unspecified parts of face
0.000 0.996 0.004
D36 Benign neoplasm of other and unspecified sites
0.000 0.996 0.004
D32.0 Cerebral meninges
0.000 0.996 0.004
D28 Benign neoplasm of other and unspecified female genital organs
0.000 0.996 0.004
D18 Haemangioma and lymphangioma, any site
0.000 0.996 0.004
D23.5 Skin of trunk
0.000 0.996 0.004
D25 Leiomyoma of uterus
0.000 0.996 0.004
D10.3 Other and unspecified parts of mouth
0.000 0.996 0.003
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.000 0.996 0.003
D10.1 Tongue
0.000 0.996 0.003
D23.2 Skin of ear and external auricular canal
0.000 0.996 0.003
D23.7 Skin of lower limb, including hip
0.000 0.996 0.003
D22.3 Melanocytic naevi of other and unspecified parts of face
0.000 0.996 0.003
D32.9 Meninges, unspecified
0.000 0.996 0.003
D23.4 Skin of scalp and neck
0.000 0.996 0.003
D32.1 Spinal meninges
0.000 0.997 0.003
D23.9 Skin, unspecified
0.000 0.997 0.003
D10.9 Pharynx, unspecified
0.000 0.997 0.003
D10.7 Hypopharynx
0.000 0.997 0.003
D10.6 Nasopharynx
0.000 0.997 0.003
D10.5 Other parts of oropharynx
0.000 0.997 0.003
D10.4 Tonsil
0.000 0.997 0.003
D10.2 Floor of mouth
0.000 0.997 0.003
D10.0 Lip
0.000 0.997 0.003
D23.6 Skin of upper limb, including shoulder
0.000 0.997 0.003
D11.0 Parotid gland
0.000 0.997 0.003
D35.0 Adrenal gland
0.000 0.997 0.003
D30.3 Bladder
0.000 0.997 0.003
D17 Benign lipomatous neoplasm
0.000 0.997 0.003
D22.2 Melanocytic naevi of ear and external auricular canal
0.000 0.997 0.003
D35.1 Parathyroid gland
0.000 0.997 0.003
D26.0 Cervix uteri
0.000 0.997 0.003
D22.6 Melanocytic naevi of upper limb, including shoulder
0.000 0.997 0.003
D11.9 Major salivary gland, unspecified
0.000 0.997 0.003
D11.7 Other major salivary glands
0.000 0.997 0.003
D22.0 Melanocytic naevi of lip
0.000 0.997 0.003
D23.0 Skin of lip
0.000 0.997 0.003
D30.9 Urinary organ, unspecified
0.000 0.997 0.003
D30.7 Other urinary organs
0.000 0.997 0.003
D30.4 Urethra
0.000 0.997 0.003
D30.2 Ureter
0.000 0.997 0.003
D30.1 Renal pelvis
0.000 0.997 0.003
D30.0 Kidney
0.000 0.997 0.003
D35.9 Endocrine gland, unspecified
0.000 0.997 0.003
D35.8 Pluriglandular involvement
0.000 0.997 0.003
D35.7 Other specified endocrine glands
0.000 0.997 0.003
D35.6 Aortic body and other paraganglia
0.000 0.997 0.003
D35.5 Carotid body
0.000 0.997 0.003
D35.4 Pineal gland
0.000 0.997 0.003
D35.3 Craniopharyngeal duct
0.000 0.997 0.003
D14.0 Middle ear, nasal cavity and accessory sinuses
0.000 0.997 0.003
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.000 0.997 0.003
D22.9 Melanocytic naevi, unspecified
0.000 0.997 0.003
D14.4 Respiratory system, unspecified
0.000 0.997 0.003
D14.3 Bronchus and lung
0.000 0.997 0.003
D14.2 Trachea
0.000 0.997 0.003
D14.1 Larynx
0.000 0.997 0.003
D15.9 Intrathoracic organ, unspecified
0.000 0.997 0.003
D15.7 Other specified intrathoracic organs
0.000 0.997 0.003
D15.2 Mediastinum
0.000 0.997 0.003
D15.1 Heart
0.000 0.997 0.003
D15.0 Thymus
0.000 0.997 0.003
D19.9 Mesothelial tissue, unspecified
0.000 0.997 0.003
D19.7 Mesothelial tissue of other sites
0.000 0.997 0.003
D19.1 Mesothelial tissue of peritoneum
0.000 0.997 0.003
D19.0 Mesothelial tissue of pleura
0.000 0.997 0.003
D20.1 Peritoneum
0.000 0.997 0.003
D20.0 Retroperitoneum
0.000 0.997 0.003
D26.9 Uterus, unspecified
0.000 0.997 0.003
D26.7 Other parts of uterus
0.000 0.997 0.003
D29.9 Male genital organ, unspecified
0.000 0.997 0.003
D29.7 Other male genital organs
0.000 0.997 0.003
D29.4 Scrotum
0.000 0.997 0.003
D29.3 Epididymis
0.000 0.997 0.003
D29.2 Testis
0.000 0.997 0.003
D29.1 Prostate
0.000 0.997 0.003
D29.0 Penis
0.000 0.997 0.003
D21.9 Connective and other soft tissue, unspecified
0.000 0.997 0.003
D21.6 Connective and other soft tissue of trunk, unspecified
0.000 0.997 0.003
D21.5 Connective and other soft tissue of pelvis
0.000 0.997 0.003
D21.4 Connective and other soft tissue of abdomen
0.000 0.997 0.003
D21.3 Connective and other soft tissue of thorax
0.000 0.997 0.003
D21.0 Connective and other soft tissue of head, face and neck
0.000 0.997 0.003
D16.9 Bone and articular cartilage, unspecified
0.000 0.997 0.003
D16.8 Pelvic bones, sacrum and coccyx
0.000 0.997 0.003
D16.7 Ribs, sternum and clavicle
0.000 0.997 0.003
D16.6 Vertebral column
0.000 0.997 0.003
D16.5 Lower jaw bone
0.000 0.997 0.003
D16.3 Short bones of lower limb
0.000 0.997 0.003
D16.2 Long bones of lower limb
0.000 0.997 0.003
D16.1 Short bones of upper limb
0.000 0.997 0.003
D16.0 Scapula and long bones of upper limb
0.000 0.997 0.003
D22.7 Melanocytic naevi of lower limb, including hip
0.000 0.997 0.003
D31.9 Eye, unspecified
0.000 0.997 0.003
D31.6 Orbit, unspecified
0.000 0.997 0.003
D31.5 Lachrymal gland and duct
0.000 0.997 0.003
D31.4 Ciliary body
0.000 0.997 0.003
D31.3 Choroid
0.000 0.997 0.003
D31.2 Retina
0.000 0.997 0.003
D31.1 Cornea
0.000 0.997 0.003
D33.9 Central nervous system, unspecified
0.000 0.997 0.003
D33.7 Other specified parts of central nervous system
0.000 0.997 0.003
D33.4 Spinal cord
0.000 0.997 0.003
D33.2 Brain, unspecified
0.000 0.997 0.003
D33.1 Brain, infratentorial
0.000 0.997 0.003
D33.0 Brain, supratentorial
0.000 0.997 0.003
D16.4 Bones of skull and face
0.000 0.997 0.003
D21.2 Connective and other soft tissue of lower limb, including hip
0.000 0.997 0.003
D22.4 Melanocytic naevi of scalp and neck
0.000 0.997 0.003
D26.1 Corpus uteri
0.000 0.997 0.003
D22.1 Melanocytic naevi of eyelid, including canthus
0.000 0.997 0.003
D31.0 Conjunctiva
0.000 0.997 0.003
D22.5 Melanocytic naevi of trunk
0.000 0.997 0.003
D25.0 Submucous leiomyoma of uterus
0.000 0.997 0.003
D35.2 Pituitary gland
0.000 0.997 0.003
D33.3 Cranial nerves
0.000 0.997 0.003
D36.9 Benign neoplasm of unspecified site
0.000 0.997 0.003
D36.1 Peripheral nerves and autonomic nervous system
0.000 0.997 0.003
D36.0 Lymph nodes
0.000 0.997 0.003
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.997 0.003
D28.9 Female genital organ, unspecified
0.000 0.997 0.003
D28.7 Other specified female genital organs
0.000 0.997 0.003
D28.2 Uterine tubes and ligaments
0.000 0.997 0.003
D28.1 Vagina
0.000 0.997 0.003
D18.1 Lymphangioma, any site
0.000 0.997 0.003
D13.2 Duodenum
0.000 0.997 0.003
D25.2 Subserosal leiomyoma of uterus
0.000 0.997 0.003
D13.9 Ill-defined sites within the digestive system
0.000 0.997 0.003
D13.7 Endocrine pancreas
0.000 0.997 0.003
D13.6 Pancreas
0.000 0.997 0.003
D13.5 Extrahepatic bile ducts
0.000 0.997 0.003
D13.4 Liver
0.000 0.997 0.003
D13.3 Other and unspecified parts of small intestine
0.000 0.997 0.003
D13.0 Oesophagus
0.000 0.997 0.003
D17.9 Benign lipomatous neoplasm, unspecified
0.000 0.997 0.003
D23.1 Skin of eyelid, including canthus
0.000 0.997 0.003
D17.7 Benign lipomatous neoplasm of other sites
0.000 0.997 0.003
D36.7 Other specified sites
0.000 0.997 0.002
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.000 0.997 0.003
D17.6 Benign lipomatous neoplasm of spermatic cord
0.000 0.997 0.003
D25.9 Leiomyoma of uterus, unspecified
0.000 0.997 0.003
D28.0 Vulva
0.000 0.997 0.002
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.000 0.997 0.002
K59.0 Constipation
0.003 0.997 0.000
N95.0 Postmenopausal bleeding
0.003 0.997 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.000 0.997 0.002
R07.4 Chest pain, unspecified
0.003 0.997 0.000
D18.0 Haemangioma, any site
0.000 0.997 0.002
D25.1 Intramural leiomyoma of uterus
0.000 0.997 0.002
Z88.6 Personal history of allergy to analgesic agent
0.000 0.998 0.002
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.000 0.998 0.002
D13.1 Stomach
0.000 0.998 0.002
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.000 0.998 0.002
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.000 0.998 0.002
I25.1 Atherosclerotic heart disease
0.002 0.998 0.000
I84.9 Unspecified haemorrhoids without complication
0.000 0.998 0.002
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.002 0.998 0.000
I83 Varicose veins of lower extremities
0.000 0.998 0.002
Z37.0 Single live birth
0.000 0.998 0.002
I25.9 Chronic ischaemic heart disease, unspecified
0.002 0.998 0.000
A41.9 Septicaemia, unspecified
0.002 0.998 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.998 0.002
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.998 0.002
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.998 0.002
H35.3 Degeneration of macula and posterior pole
0.002 0.998 0.000
Z88.2 Personal history of allergy to sulphonamides
0.000 0.998 0.002
Y45.0 Opioids and related analgesics
0.001 0.998 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.000 0.998 0.002
A41 Other septicaemia
0.002 0.998 0.000
Y43.3 Other antineoplastic drugs
0.001 0.998 0.000
I25 Chronic ischaemic heart disease
0.002 0.998 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.000 0.998 0.001
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.998 0.001
Z88.7 Personal history of allergy to serum and vaccine
0.000 0.998 0.001
Y86 Sequelae of other accidents
0.001 0.999 0.000
A41.8 Other specified septicaemia
0.001 0.999 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.001 0.999 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.001 0.999 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.001 0.999 0.000
O70.0 First degree perineal laceration during delivery
0.000 0.999 0.001
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.000 0.999 0.001
Z88.1 Personal history of allergy to other antibiotic agents
0.000 0.999 0.001
R07.2 Precordial pain
0.001 0.999 0.000
Z88.5 Personal history of allergy to narcotic agent
0.000 0.999 0.001
Y43 Primarily systemic agents
0.001 0.999 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.001 0.999 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.001 0.999 0.000
A41.4 Septicaemia due to anaerobes
0.001 0.999 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.001 0.999 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.001 0.999 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.001 0.999 0.000
Z88.0 Personal history of allergy to penicillin
0.000 0.999 0.001
I25.6 Silent myocardial ischaemia
0.001 0.999 0.000
I25.4 Coronary artery aneurysm
0.001 0.999 0.000
I25.3 Aneurysm of heart
0.001 0.999 0.000
Y43.0 Antiallergic and antiemetic drugs
0.001 0.999 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.000 0.999 0.001
I84 Haemorrhoids
0.000 0.999 0.001
I25.5 Ischaemic cardiomyopathy
0.001 0.999 0.000
R07 Pain in throat and chest
0.001 0.999 0.000
M10.99 Gout, unspecified (Site unspecified)
0.000 0.999 0.001
Y43.1 Antineoplastic antimetabolites
0.001 0.999 0.000
Y45.2 Propionic acid derivatives
0.001 0.999 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.001 0.999 0.000
Y43.9 Primarily systemic agent, unspecified
0.001 0.999 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.001 0.999 0.000
Y43.6 Enzymes, not elsewhere classified
0.001 0.999 0.000
Y43.5 Acidifying and alkalising agents
0.001 0.999 0.000
Y43.4 Immunosuppressive agents
0.001 0.999 0.000
Y43.2 Antineoplastic natural products
0.001 0.999 0.000
K66.0 Peritoneal adhesions
0.001 0.999 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.001 0.999 0.000
I84.3 External thrombosed haemorrhoids
0.000 0.999 0.001
J18.1 Lobar pneumonia, unspecified
0.001 0.999 0.000
R07.1 Chest pain on breathing
0.001 0.999 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.001 0.999 0.000
Y45.8 Other analgesics and antipyretics
0.001 0.999 0.000
Y45.5 4-Aminophenol derivatives
0.001 0.999 0.000
Y45.4 Antirheumatics
0.001 0.999 0.000
Y45.1 Salicylates
0.001 0.999 0.000
Z37 Outcome of delivery
0.000 0.999 0.001
I84.4 External haemorrhoids with other complications
0.000 0.999 0.001
I84.0 Internal thrombosed haemorrhoids
0.000 0.999 0.001
R07.0 Pain in throat
0.001 0.999 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.999 0.001
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.001 0.999 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.999 0.001
I82 Other venous embolism and thrombosis
0.000 0.999 0.001
Y52 Agents primarily affecting the cardiovascular system
0.001 0.999 0.000
A49.0 Staphylococcal infection, unspecified
0.001 0.999 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.001 0.999 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.001 0.999 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.001 0.999 0.000
I50.1 Left ventricular failure
0.001 0.999 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.999 0.001
Z37.9 Outcome of delivery unspecified
0.000 0.999 0.001
Z37.7 Other multiple births, all stillborn
0.000 0.999 0.001
Z37.6 Other multiple births, some liveborn
0.000 0.999 0.001
Z37.5 Other multiple births, all liveborn
0.000 0.999 0.001
Z37.4 Twins, both stillborn
0.000 0.999 0.001
Z37.3 Twins, one liveborn and one stillborn
0.000 0.999 0.001
Z37.1 Single stillbirth
0.000 0.999 0.001
I87 Other disorders of veins
0.000 0.999 0.001
I80 Phlebitis and thrombophlebitis
0.000 0.999 0.001
N95 Menopausal and other perimenopausal disorders
0.001 0.999 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.001 0.999 0.000
Y88 Sequelae of surgical and medical care as external cause
0.001 0.999 0.000
H35.4 Peripheral retinal degeneration
0.001 0.999 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.001 0.999 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.999 0.001
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.999 0.001
I84.8 Unspecified haemorrhoids with other complications
0.000 0.999 0.001
I84.6 Residual haemorrhoidal skin tags
0.000 0.999 0.001
Y42.7 Androgens and anabolic congeners
0.001 0.999 0.000
I88 Nonspecific lymphadenitis
0.000 0.999 0.001
K44 Diaphragmatic hernia
0.001 0.999 0.000
Y59 Other and unspecified vaccines and biological substances
0.001 0.999 0.000
Y58 Bacterial vaccines
0.001 0.999 0.000
Y57 Other and unspecified drugs and medicaments
0.001 0.999 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.001 0.999 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.001 0.999 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.001 0.999 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.001 0.999 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.001 0.999 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.001 0.999 0.000
Y48 Anaesthetics and therapeutic gases
0.001 0.999 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.001 0.999 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.001 0.999 0.000
Y40 Systemic antibiotics
0.001 0.999 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.001 0.999 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.999 0.001
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.999 0.001
I82.8 Embolism and thrombosis of other specified veins
0.000 0.999 0.001
I87.1 Compression of vein
0.000 0.999 0.001
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.001 0.999 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.001 0.999 0.000
Y52.7 Peripheral vasodilators
0.001 0.999 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.001 0.999 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.001 0.999 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.001 0.999 0.000
Y52.1 Calcium-channel blockers
0.001 0.999 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.001 0.999 0.000
I85 Oesophageal varices
0.000 0.999 0.001
Y51 Drugs primarily affecting the autonomic nervous system
0.001 0.999 0.000
Y89 Sequelae of other external causes
0.001 0.999 0.000
I82.3 Embolism and thrombosis of renal vein
0.000 0.999 0.001
I82.2 Embolism and thrombosis of vena cava
0.000 0.999 0.001
I82.1 Thrombophlebitis migrans
0.000 0.999 0.001
I82.0 Budd-Chiari syndrome
0.000 0.999 0.001
I84.5 External haemorrhoids without complication
0.000 0.999 0.001
N95.1 Menopausal and female climacteric states
0.001 0.999 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.001 0.999 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.001 0.999 0.000
Y89.9 Sequelae of unspecified external cause
0.001 0.999 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.001 0.999 0.000
H35 Other retinal disorders
0.001 0.999 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.999 0.001
I81 Portal vein thrombosis
0.000 0.999 0.001
Y44 Agents primarily affecting blood constituents
0.001 0.999 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.001 0.999 0.000
H35.9 Retinal disorder, unspecified
0.001 0.999 0.000
H35.5 Hereditary retinal dystrophy
0.001 0.999 0.000
I87.9 Disorder of vein, unspecified
0.000 0.999 0.001
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.999 0.001
I87.0 Postphlebitic syndrome
0.000 0.999 0.001
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.999 0.001
I88.8 Other nonspecific lymphadenitis
0.000 0.999 0.001
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.999 0.001
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.999 0.001
K51.9 Ulcerative colitis, unspecified
0.000 0.999 0.001
N95.9 Menopausal and perimenopausal disorder, unspecified
0.001 0.999 0.000
N95.3 States associated with artificial menopause
0.001 0.999 0.000
Y40.9 Systemic antibiotic, unspecified
0.001 0.999 0.000
Y40.8 Other systemic antibiotics
0.001 0.999 0.000
Y40.7 Antifungal antibiotics, systemically used
0.001 0.999 0.000
Y40.6 Rifamycins
0.001 0.999 0.000
Y40.5 Aminoglycosides
0.001 0.999 0.000
Y40.4 Tetracyclines
0.001 0.999 0.000
Y40.3 Macrolides
0.001 0.999 0.000
Y40.2 Chloramphenicol group
0.001 0.999 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.001 0.999 0.000
Y42.9 Other and unspecified hormone antagonists
0.001 0.999 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.001 0.999 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.001 0.999 0.000
Y42.4 Oral contraceptives
0.001 0.999 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.001 0.999 0.000
Y42.2 Antithyroid drugs
0.001 0.999 0.000
Y42.1 Thyroid hormones and substitutes
0.001 0.999 0.000
Y57.9 Drug or medicament, unspecified
0.001 0.999 0.000
Y57.8 Other drugs and medicaments
0.001 0.999 0.000
Y57.7 Vitamins, not elsewhere classified
0.001 0.999 0.000
Y57.6 Other diagnostic agents
0.001 0.999 0.000
Y57.5 X-ray contrast media
0.001 0.999 0.000
Y57.4 Pharmaceutical excipients
0.001 0.999 0.000
Y57.3 Alcohol deterrents
0.001 0.999 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.001 0.999 0.000
Y57.1 Lipotropic drugs
0.001 0.999 0.000
Y57.0 Appetite depressants [anorectics]
0.001 0.999 0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use
0.001 0.999 0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures
0.001 0.999 0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
0.001 0.999 0.000
I86 Varicose veins of other sites
0.000 0.999 0.001
O70 Perineal laceration during delivery
0.000 0.999 0.001
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.999 0.001
I85.0 Oesophageal varices with bleeding
0.000 0.999 0.001
K44.1 Diaphragmatic hernia with gangrene
0.001 0.999 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.001 0.999 0.000
L81.4 Other melanin hyperpigmentation
0.001 0.999 0.000
R49.0 Dysphonia
0.001 0.999 0.000
Y40.0 Penicillins
0.001 0.999 0.000
Y46.8 Antispasticity drugs
0.001 0.999 0.000
Y46.7 Anti-Parkinsonism drugs
0.001 0.999 0.000
Y46.6 Other and unspecified antiepileptics
0.001 0.999 0.000
Y46.5 Valproic acid
0.001 0.999 0.000
Y46.4 Iminostilbenes
0.001 0.999 0.000
Y46.3 Deoxybarbiturates
0.001 0.999 0.000
Y46.2 Hydantoin derivatives
0.001 0.999 0.000
Y46.1 Oxazolidinediones
0.001 0.999 0.000
Y46.0 Succinimides
0.001 0.999 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.001 0.999 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.001 0.999 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.001 0.999 0.000
Y47.4 Bromine compounds
0.001 0.999 0.000
Y47.3 Paraldehyde
0.001 0.999 0.000
Y47.2 Chloral derivatives
0.001 0.999 0.000
Y47.1 Benzodiazepines
0.001 0.999 0.000
Y47.0 Barbiturates, not elsewhere classified
0.001 0.999 0.000
Y48.5 Therapeutic gases
0.001 0.999 0.000
Y48.4 Anaesthetic, unspecified
0.001 0.999 0.000
Y48.3 Local anaesthetics
0.001 0.999 0.000
Y48.2 Other and unspecified general anaesthetics
0.001 0.999 0.000
Y48.1 Parenteral anaesthetics
0.001 0.999 0.000
Y48.0 Inhaled anaesthetics
0.001 0.999 0.000
Y49.9 Psychotropic drug, unspecified
0.001 0.999 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.001 0.999 0.000
Y49.7 Psychostimulants with abuse potential
0.001 0.999 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.001 0.999 0.000
Y49.5 Other antipsychotics and neuroleptics
0.001 0.999 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.001 0.999 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.001 0.999 0.000
Y49.2 Other and unspecified antidepressants
0.001 0.999 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.001 0.999 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.001 0.999 0.000
Y50.9 Central nervous system stimulant, unspecified
0.001 0.999 0.000
Y50.8 Other central nervous system stimulants
0.001 0.999 0.000
Y50.2 Methylxanthines, not elsewhere classified
0.001 0.999 0.000
Y50.1 Opioid receptor antagonists
0.001 0.999 0.000
Y50.0 Analeptics
0.001 0.999 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.001 0.999 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.001 0.999 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.001 0.999 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.001 0.999 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.001 0.999 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.001 0.999 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.001 0.999 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.001 0.999 0.000
Y51.0 Anticholinesterase agents
0.001 0.999 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.001 0.999 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.001 0.999 0.000
Y53.7 Emetics
0.001 0.999 0.000
Y53.6 Antidiarrhoeal drugs
0.001 0.999 0.000
Y53.5 Digestants
0.001 0.999 0.000
Y53.4 Other laxatives
0.001 0.999 0.000
Y53.3 Saline and osmotic laxatives
0.001 0.999 0.000
Y53.2 Stimulant laxatives
0.001 0.999 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.001 0.999 0.000
Y53.0 Histamine H2-receptor antagonists
0.001 0.999 0.000
Y54.9 Mineral salts, not elsewhere classified
0.001 0.999 0.000
Y54.8 Agents affecting uric acid metabolism
0.001 0.999 0.000
Y54.7 Agents affecting calcification
0.001 0.999 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.001 0.999 0.000
Y54.5 Other diuretics
0.001 0.999 0.000
Y54.4 Loop [high-ceiling] diuretics
0.001 0.999 0.000
Y54.3 Benzothiadiazine derivatives
0.001 0.999 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.001 0.999 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.001 0.999 0.000
Y54.0 Mineralocorticoids
0.001 0.999 0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.001 0.999 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.001 0.999 0.000
Y55.5 Anticommon cold drugs
0.001 0.999 0.000
Y55.4 Expectorants
0.001 0.999 0.000
Y55.3 Antitussives
0.001 0.999 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.001 0.999 0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.001 0.999 0.000
Y55.0 Oxytocic drugs
0.001 0.999 0.000
Y56.9 Topical agent, unspecified
0.001 0.999 0.000
Y56.8 Other topical agents
0.001 0.999 0.000
Y56.7 Dental drugs, topically applied
0.001 0.999 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.001 0.999 0.000
Y56.5 Ophthalmological drugs and preparations
0.001 0.999 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.001 0.999 0.000
Y56.3 Emollients, demulcents and protectants
0.001 0.999 0.000
Y56.2 Local astringents and local detergents
0.001 0.999 0.000
Y56.1 Antipruritics
0.001 0.999 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.001 0.999 0.000
Y58.9 Other and unspecified bacterial vaccines
0.001 0.999 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.001 0.999 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.001 0.999 0.000
Y58.5 Diphtheria vaccine
0.001 0.999 0.000
Y58.4 Tetanus vaccine
0.001 0.999 0.000
Y58.3 Plague vaccine
0.001 0.999 0.000
Y58.2 Cholera vaccine
0.001 0.999 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.001 0.999 0.000
Y58.0 BCG vaccine
0.001 0.999 0.000
Y59.9 Vaccine or biological substance, unspecified
0.001 0.999 0.000
Y59.8 Other specified vaccines and biological substances
0.001 0.999 0.000
Y59.3 Immunoglobulin
0.001 0.999 0.000
Y59.2 Protozoal vaccines
0.001 0.999 0.000
Y59.1 Rickettsial vaccines
0.001 0.999 0.000
Y59.0 Viral vaccines
0.001 0.999 0.000
Y89.1 Sequelae of war operations
0.001 0.999 0.000
Y89.0 Sequelae of legal intervention
0.001 0.999 0.000
Z37.2 Twins, both liveborn
0.000 0.999 0.001
A49 Bacterial infection of unspecified site
0.001 0.999 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.001 0.999 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.001 0.999 0.000
H35.7 Separation of retinal layers
0.001 0.999 0.000
H35.2 Other proliferative retinopathy
0.001 0.999 0.000
H35.1 Retinopathy of prematurity
0.001 0.999 0.000
I87.8 Other specified disorders of veins
0.000 0.999 0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.999 0.001
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.999 0.001
I89.1 Lymphangitis
0.000 0.999 0.001
M51.2 Other specified intervertebral disk displacement
0.001 0.999 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.001 0.999 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.000 0.999 0.001
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.001 0.999 0.000
Y41.5 Antiviral drugs
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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