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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs130078
log Bayes Factor = 57.3546
Chromosome 6   position 31,118,565  (GRCh37) Explore rs130078 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.007 0.993
G35 Multiple sclerosis
0.991 0.009 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.011 0.989
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.013 0.987
E70-E90 Metabolic disorders
0.000 0.017 0.983
E14 Unspecified diabetes mellitus
0.000 0.047 0.953
L40 Psoriasis
0.000 0.049 0.951
L40.5 Arthropathic psoriasis
0.000 0.106 0.894
E07 Other disorders of thyroid
0.000 0.115 0.885
E11.0 With coma
0.000 0.117 0.883
E78.8 Other disorders of lipoprotein metabolism
0.000 0.124 0.876
E14.3 With ophthalmic complications
0.000 0.146 0.854
E10.3 With ophthalmic complications
0.000 0.153 0.847
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.161 0.839
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.168 0.832
E78.2 Mixed hyperlipidaemia
0.000 0.172 0.828
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.184 0.816
L40.0 Psoriasis vulgaris
0.000 0.189 0.811
E07.9 Disorder of thyroid, unspecified
0.000 0.189 0.811
E03.8 Other specified hypothyroidism
0.000 0.191 0.809
E14.9 Without complications
0.000 0.192 0.808
G35-G37 Demyelinating diseases of the central nervous system
0.784 0.216 0.000
L40.8 Other psoriasis
0.000 0.223 0.777
E11.1 With ketoacidosis
0.000 0.226 0.774
E79 Disorders of purine and pyrimidine metabolism
0.000 0.230 0.770
E74 Other disorders of carbohydrate metabolism
0.000 0.232 0.768
E78.4 Other hyperlipidaemia
0.000 0.233 0.767
E10.6 With other specified complications
0.000 0.244 0.756
E11.2 With renal complications
0.000 0.244 0.756
E10.8 With unspecified complications
0.000 0.247 0.753
E14.5 With peripheral circulatory complications
0.000 0.247 0.753
E78.1 Pure hyperglyceridaemia
0.000 0.250 0.750
E78.5 Hyperlipidaemia, unspecified
0.000 0.264 0.736
E40-E46 Malnutrition
0.000 0.268 0.732
E14.6 With other specified complications
0.000 0.271 0.729
G37 Other demyelinating diseases of central nervous system
0.727 0.273 0.000
L40.1 Generalised pustular psoriasis
0.000 0.273 0.727
E10.1 With ketoacidosis
0.000 0.277 0.722
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.288 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.288 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.288 0.712
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.288 0.712
E10.0 With coma
0.000 0.288 0.712
E14.4 With neurological complications
0.000 0.288 0.711
E78.6 Lipoprotein deficiency
0.000 0.290 0.710
E78.3 Hyperchylomicronaemia
0.000 0.292 0.708
E83 Disorders of mineral metabolism
0.677 0.293 0.029
E77 Disorders of glycoprotein metabolism
0.000 0.295 0.705
E76 Disorders of glycosaminoglycan metabolism
0.000 0.295 0.705
E72 Other disorders of amino-acid metabolism
0.000 0.295 0.705
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.295 0.705
E70 Disorders of aromatic amino-acid metabolism
0.000 0.295 0.705
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.295 0.705
E13 Other specified diabetes mellitus
0.000 0.298 0.702
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.308 0.692
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.311 0.689
K90 Intestinal malabsorption
0.000 0.311 0.689
E14.1 With ketoacidosis
0.000 0.313 0.687
E16 Other disorders of pancreatic internal secretion
0.000 0.316 0.684
E14.7 With multiple complications
0.000 0.317 0.683
E14.0 With coma
0.000 0.317 0.683
L40.2 Acrodermatitis continua
0.000 0.318 0.682
E84 Cystic fibrosis
0.000 0.321 0.679
E14.2 Withrenal complications
0.000 0.323 0.677
L40.4 Guttate psoriasis
0.000 0.324 0.676
G37.9 Demyelinating disease of central nervous system, unspecified
0.670 0.330 0.000
E80.4 Gilbert's syndrome
0.000 0.337 0.663
E80.6 Other disorders of bilirubin metabolism
0.000 0.344 0.656
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.352 0.648
E14.8 With unspecified complications
0.000 0.357 0.643
E80.2 Other porphyria
0.000 0.364 0.636
E03.1 Congenital hypothyroidism without goitre
0.000 0.365 0.635
E07.1 Dyshormogenetic goitre
0.000 0.365 0.635
E07.0 Hypersecretion of calcitonin
0.000 0.365 0.635
E11.8 With unspecified complications
0.000 0.370 0.630
E05.8 Other thyrotoxicosis
0.000 0.376 0.623
E10.2 With renal complications
0.000 0.379 0.621
G36 Other acute disseminated demyelination
0.618 0.382 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.383 0.617
E10.5 With peripheral circulatory complications
0.000 0.387 0.613
E07.8 Other specified disorders of thyroid
0.000 0.392 0.608
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.395 0.604
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.403 0.597
E80.5 Crigler-Najjar syndrome
0.000 0.403 0.597
E80.3 Defects of catalase and peroxydase
0.000 0.403 0.597
E80.0 Hereditary erythropoietic porphyria
0.000 0.403 0.597
E80.1 Porphyria cutanea tarda
0.000 0.408 0.592
E15 Nondiabetic hypoglycaemic coma
0.000 0.415 0.585
G37.8 Other specified demyelinating diseases of central nervous system
0.584 0.416 0.000
E83.3 Disorders of phosphorus metabolism
0.574 0.417 0.009
E88 Other metabolic disorders
0.000 0.421 0.579
E16.2 Hypoglycaemia, unspecified
0.000 0.429 0.571
E10.4 With neurological complications
0.000 0.438 0.561
L40.3 Pustulosis palmaris et plantaris
0.000 0.440 0.560
E73 Lactose intolerance
0.000 0.441 0.559
L40-L45 Papulosquamous disorders
0.000 0.444 0.556
E11.5 With peripheral circulatory complications
0.000 0.445 0.555
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.448 0.552
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.448 0.552
E79.1 Lesch-Nyhan syndrome
0.000 0.448 0.552
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.449 0.551
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.449 0.551
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.449 0.551
E74.2 Disorders of galactose metabolism
0.000 0.449 0.551
E74.1 Disorders of fructose metabolism
0.000 0.449 0.551
E83.9 Disorder of mineral metabolism, unspecified
0.525 0.457 0.019
E46 Unspecified protein-energy malnutrition
0.000 0.461 0.539
K90.9 Intestinal malabsorption, unspecified
0.000 0.470 0.530
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.475 0.525
E45 Retarded development following protein-energy malnutrition
0.000 0.475 0.525
E43 Unspecified severe protein-energy malnutrition
0.000 0.475 0.525
E42 Marasmic kwashiorkor
0.000 0.475 0.525
E41 Nutritional marasmus
0.000 0.475 0.525
E40 Kwashiorkor
0.000 0.475 0.525
G37.5 Concentric sclerosis [Balo]
0.521 0.479 0.000
G37.4 Subacute necrotising myelitis
0.521 0.479 0.000
G37.2 Central pontine myelinolysis
0.521 0.479 0.000
G37.1 Central demyelination of corpus callosum
0.521 0.479 0.000
G37.0 Diffuse sclerosis
0.521 0.479 0.000
E16.1 Other hypoglycaemia
0.000 0.483 0.517
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.515 0.484 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.487 0.513
E13.9 Without complications
0.000 0.488 0.512
E83.8 Other disorders of mineral metabolism
0.486 0.493 0.021
E83.2 Disorders of zinc metabolism
0.486 0.493 0.021
E83.0 Disorders of copper metabolism
0.486 0.493 0.021
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.494 0.505
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.494 0.505
E70.3 Albinism
0.000 0.494 0.505
E70.2 Disorders of tyrosine metabolism
0.000 0.494 0.505
E70.1 Other hyperphenylalaninaemias
0.000 0.494 0.505
E70.0 Classical phenylketonuria
0.000 0.494 0.505
E71.3 Disorders of fatty-acid metabolism
0.000 0.494 0.505
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.494 0.505
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.494 0.505
E71.0 Maple-syrup-urine disease
0.000 0.494 0.505
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.494 0.505
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.494 0.505
E72.5 Disorders of glycine metabolism
0.000 0.494 0.505
E72.4 Disorders of ornithine metabolism
0.000 0.494 0.505
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.494 0.505
E72.2 Disorders of urea cycle metabolism
0.000 0.494 0.505
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.494 0.505
E72.0 Disorders of amino-acid transport
0.000 0.494 0.505
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.494 0.505
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.494 0.505
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.494 0.505
E76.2 Other mucopolysaccharidoses
0.000 0.494 0.505
E76.1 Mucopolysaccharidosis, type II
0.000 0.494 0.505
E76.0 Mucopolysaccharidosis, type I
0.000 0.494 0.505
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.494 0.505
E77.8 Other disorders of glycoprotein metabolism
0.000 0.494 0.505
E77.1 Defects in glycoprotein degradation
0.000 0.494 0.505
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.494 0.505
E13.8 With unspecified complications
0.000 0.496 0.503
E13.7 With multiple complications
0.000 0.496 0.503
E13.6 With other specified complications
0.000 0.496 0.503
E13.5 With peripheral circulatory complications
0.000 0.496 0.503
E13.4 With neurological complications
0.000 0.496 0.503
E13.2 With renal complications
0.000 0.496 0.503
E13.1 With ketoacidosis
0.000 0.496 0.503
E13.0 With coma
0.000 0.496 0.503
G36.0 Neuromyelitis optica [Devic]
0.499 0.501 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.503 0.497
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.504 0.496
K90.8 Other intestinal malabsorption
0.000 0.505 0.495
M06.9 Rheumatoid arthritis, unspecified
0.000 0.505 0.495
E75.6 Lipid storage disorder, unspecified
0.000 0.506 0.494
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.506 0.494
E75.3 Sphingolipidosis, unspecified
0.000 0.506 0.494
E75.2 Other sphingolipidosis
0.000 0.506 0.494
E75.1 Other gangliosidosis
0.000 0.506 0.494
E75.0 GM2 gangliosidosis
0.000 0.506 0.494
K90.3 Pancreatic steatorrhoea
0.000 0.506 0.494
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.506 0.494
K90.1 Tropical sprue
0.000 0.506 0.494
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.509 0.490
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.509 0.490
E16.4 Abnormal secretion of gastrin
0.000 0.509 0.490
E16.3 Increased secretion of glucagon
0.000 0.509 0.490
E74.0 Glycogen storage disease
0.000 0.510 0.490
E84.8 Cystic fibrosis with other manifestations
0.000 0.513 0.487
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.513 0.487
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.513 0.487
E11.6 With other specified complications
0.000 0.514 0.485
E75.5 Other lipid storage disorders
0.000 0.521 0.479
E13.3 With ophthalmic complications
0.000 0.521 0.478
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.536 0.464
E11.4 With neurological complications
0.000 0.538 0.462
E84.9 Cystic fibrosis, unspecified
0.000 0.538 0.461
E88.2 Lipomatosis, not elsewhere classified
0.000 0.547 0.453
L43 Lichen planus
0.000 0.548 0.452
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.556 0.443
G36.9 Acute disseminated demyelination, unspecified
0.443 0.557 0.000
G36.8 Other specified acute disseminated demyelination
0.443 0.557 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.443 0.557 0.000
E85 Amyloidosis
0.001 0.559 0.441
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.564 0.436
L42 Pityriasis rosea
0.000 0.565 0.435
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.576 0.424
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.579 0.421
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.582 0.418
E88.9 Metabolic disorder, unspecified
0.000 0.585 0.415
E88.8 Other specified metabolic disorders
0.000 0.585 0.415
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.588 0.412
E88.3 Tumour lysis syndrome
0.000 0.589 0.410
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.593 0.407
E83.4 Disorders of magnesium metabolism
0.394 0.596 0.010
L43.9 Lichen planus, unspecified
0.000 0.597 0.403
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.598 0.402
E73.8 Other lactose intolerance
0.000 0.599 0.401
E73.1 Secondary lactase deficiency
0.000 0.599 0.401
E73.0 Congenital lactase deficiency
0.000 0.599 0.401
L44 Other papulosquamous disorders
0.000 0.601 0.399
L41 Parapsoriasis
0.000 0.601 0.399
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.601 0.399
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.604 0.396
E89.4 Postprocedural ovarian failure
0.000 0.609 0.391
E06 Thyroiditis
0.000 0.615 0.384
E44.1 Mild protein-energy malnutrition
0.000 0.624 0.376
E44.0 Moderate protein-energy malnutrition
0.000 0.624 0.376
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.627 0.373
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.627 0.373
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.632 0.368
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.632 0.368
E89.5 Postprocedural testicular hypofunction
0.000 0.632 0.368
E89.1 Postprocedural hypoinsulinaemia
0.000 0.632 0.368
E83.5 Disorders of calcium metabolism
0.356 0.641 0.003
E89.3 Postprocedural hypopituitarism
0.000 0.659 0.341
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.661 0.339
E65-E68 Obesity and other hyperalimentation
0.000 0.668 0.331
L43.3 Subacute (active) lichen planus
0.000 0.676 0.324
L43.2 Lichenoid drug reaction
0.000 0.676 0.324
L43.1 Bullous lichen planus
0.000 0.676 0.324
L43.0 Hypertrophic lichen planus
0.000 0.676 0.324
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.684 0.316
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.684 0.316
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.684 0.316
E89.2 Postprocedural hypoparathyroidism
0.000 0.686 0.313
E20-E35 Disorders of other endocrine glands
0.000 0.689 0.311
E50-E64 Other nutritional deficiencies
0.000 0.692 0.308
C83.3 Large cell (diffuse)
0.000 0.695 0.305
E85.8 Other amyloidosis
0.001 0.699 0.300
E85.9 Amyloidosis, unspecified
0.000 0.702 0.297
L41.9 Parapsoriasis, unspecified
0.000 0.714 0.286
L41.8 Other parapsoriasis
0.000 0.714 0.286
L41.5 Retiform parapsoriasis
0.000 0.714 0.286
L41.4 Large plaque parapsoriasis
0.000 0.714 0.286
L41.3 Small plaque parapsoriasis
0.000 0.714 0.286
L41.2 Lymphomatoid papulosis
0.000 0.714 0.286
L41.1 Pityriasis lichenoides chronica
0.000 0.714 0.286
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.714 0.286
L44.9 Papulosquamous disorder, unspecified
0.000 0.714 0.286
L44.8 Other specified papulosquamous disorders
0.000 0.714 0.286
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.714 0.286
L44.3 Lichen ruber moniliformis
0.000 0.714 0.286
L44.2 Lichen striatus
0.000 0.714 0.286
L44.1 Lichen nitidus
0.000 0.714 0.286
L44.0 Pityriasis rubra pilaris
0.000 0.714 0.286
E28 Ovarian dysfunction
0.000 0.723 0.277
E06.5 Other chronic thyroiditis
0.000 0.724 0.276
E06.4 Drug-induced thyroiditis
0.000 0.724 0.276
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.724 0.276
E06.0 Acute thyroiditis
0.000 0.724 0.276
E11.3 With ophthalmic complications
0.000 0.729 0.271
E06.1 Subacute thyroiditis
0.000 0.737 0.262
E28.2 Polycystic ovarian syndrome
0.000 0.738 0.262
L43.8 Other lichen planus
0.000 0.740 0.260
E85.4 Organ-limited amyloidosis
0.001 0.743 0.256
E73.9 Lactose intolerance, unspecified
0.001 0.745 0.255
E23 Hypofunction and other disorders of pituitary gland
0.000 0.755 0.245
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.756 0.244
E24 Cushing's syndrome
0.000 0.760 0.240
E67 Other hyperalimentation
0.000 0.762 0.238
E68 Sequelae of hyperalimentation
0.000 0.762 0.238
E85.3 Secondary systemic amyloidosis
0.001 0.762 0.237
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.763 0.236
M06 Other rheumatoid arthritis
0.000 0.765 0.235
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.768 0.232
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.777 0.223
E32 Diseases of thymus
0.000 0.777 0.223
E31 Polyglandular dysfunction
0.000 0.777 0.223
E30 Disorders of puberty, not elsewhere classified
0.000 0.777 0.223
E25 Adrenogenital disorders
0.000 0.777 0.223
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.779 0.221
E63 Other nutritional deficiencies
0.000 0.779 0.221
E50 Vitamin A deficiency
0.000 0.779 0.221
E60 Dietary zinc deficiency
0.000 0.779 0.221
E59 Dietary selenium deficiency
0.000 0.779 0.221
E54 Ascorbic acid deficiency
0.000 0.779 0.221
E52 Niacin deficiency [pellagra]
0.000 0.779 0.221
E21.3 Hyperparathyroidism, unspecified
0.000 0.780 0.220
E56 Other vitamin deficiencies
0.000 0.783 0.217
E51 Thiamine deficiency
0.000 0.784 0.216
E58 Dietary calcium deficiency
0.000 0.786 0.214
E26 Hyperaldosteronism
0.000 0.790 0.210
E61 Deficiency of other nutrient elements
0.000 0.794 0.206
M06.3 Rheumatoid nodule
0.000 0.797 0.203
E23.7 Disorder of pituitary gland, unspecified
0.000 0.800 0.200
E28.9 Ovarian dysfunction, unspecified
0.000 0.801 0.199
E28.8 Other ovarian dysfunction
0.000 0.801 0.199
E28.1 Androgen excess
0.000 0.801 0.199
E28.0 Oestrogen excess
0.000 0.801 0.199
E23.2 Diabetes insipidus
0.000 0.805 0.195
E24.2 Drug-induced Cushing's syndrome
0.000 0.814 0.186
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.814 0.186
E20 Hypoparathyroidism
0.000 0.816 0.183
E06.3 Autoimmune thyroiditis
0.000 0.818 0.181
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.820 0.180
E24.9 Cushing's syndrome, unspecified
0.000 0.824 0.176
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.824 0.176
E23.1 Drug-induced hypopituitarism
0.000 0.824 0.176
E65 Localised adiposity
0.000 0.824 0.175
E21.4 Other specified disorders of parathyroid gland
0.000 0.825 0.175
E21.2 Other hyperparathyroidism
0.000 0.825 0.175
E06.9 Thyroiditis, unspecified
0.001 0.826 0.173
M06.4 Inflammatory polyarthropathy
0.000 0.827 0.173
E29 Testicular dysfunction
0.000 0.827 0.173
E24.8 Other Cushing's syndrome
0.000 0.827 0.172
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.827 0.172
E24.3 Ectopic ACTH syndrome
0.000 0.827 0.172
E24.1 Nelson's syndrome
0.000 0.827 0.172
E24.0 Pituitary-dependent Cushing's disease
0.000 0.827 0.172
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.828 0.172
E67.8 Other specified hyperalimentation
0.000 0.829 0.170
E67.3 Hypervitaminosis D
0.000 0.829 0.170
E67.2 Megavitamin-B6 syndrome
0.000 0.829 0.170
E67.1 Hypercarotenaemia
0.000 0.829 0.170
E67.0 Hypervitaminosis A
0.000 0.829 0.170
M06.34 Rheumatoid nodule (Hand)
0.000 0.830 0.170
M06.2 Rheumatoid bursitis
0.000 0.831 0.169
M06.1 Adult-onset Still's disease
0.000 0.831 0.169
M06.8 Other specified rheumatoid arthritis
0.000 0.835 0.165
E23.6 Other disorders of pituitary gland
0.000 0.836 0.164
E25.9 Adrenogenital disorder, unspecified
0.000 0.840 0.160
E25.8 Other adrenogenital disorders
0.000 0.840 0.160
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.840 0.160
E30.9 Disorder of puberty, unspecified
0.000 0.840 0.160
E30.8 Other disorders of puberty
0.000 0.840 0.160
E30.1 Precocious puberty
0.000 0.840 0.160
E30.0 Delayed puberty
0.000 0.840 0.160
E31.9 Polyglandular dysfunction, unspecified
0.000 0.840 0.160
E31.8 Other polyglandular dysfunction
0.000 0.840 0.160
E31.1 Polyglandular hyperfunction
0.000 0.840 0.160
E31.0 Autoimmune polyglandular failure
0.000 0.840 0.160
E32.9 Disease of thymus, unspecified
0.000 0.840 0.160
E32.8 Other diseases of thymus
0.000 0.840 0.160
E32.1 Abscess of thymus
0.000 0.840 0.160
E32.0 Persistent hyperplasia of thymus
0.000 0.840 0.160
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.840 0.160
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.840 0.160
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.840 0.160
E23.0 Hypopituitarism
0.000 0.840 0.160
E50.9 Vitamin A deficiency, unspecified
0.000 0.841 0.159
E50.8 Other manifestations of vitamin A deficiency
0.000 0.841 0.159
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.841 0.159
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.841 0.159
E50.5 Vitamin A deficiency with night blindness
0.000 0.841 0.159
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.841 0.159
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.841 0.159
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.841 0.159
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.841 0.159
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.841 0.159
E63.9 Nutritional deficiency, unspecified
0.000 0.841 0.159
E63.8 Other specified nutritional deficiencies
0.000 0.841 0.159
E63.1 Imbalance of constituents of food intake
0.000 0.841 0.159
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.841 0.159
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.841 0.159
E64.8 Sequelae of other nutritional deficiencies
0.000 0.841 0.159
E64.3 Sequelae of rickets
0.000 0.841 0.159
E64.2 Sequelae of vitamin C deficiency
0.000 0.841 0.159
E64.1 Sequelae of vitamin A deficiency
0.000 0.841 0.159
E64.0 Sequelae of protein-energy malnutrition
0.000 0.841 0.159
E55 Vitamin D deficiency
0.000 0.841 0.159
E56.9 Vitamin deficiency, unspecified
0.000 0.844 0.155
E56.8 Deficiency of other vitamins
0.000 0.844 0.155
E56.0 Deficiency of vitamin E
0.000 0.844 0.155
E51.9 Thiamine deficiency, unspecified
0.000 0.845 0.155
E51.8 Other manifestations of thiamine deficiency
0.000 0.845 0.155
E51.1 Beriberi
0.000 0.845 0.155
E28.3 Primary ovarian failure
0.000 0.845 0.154
E22 Hyperfunction of pituitary gland
0.000 0.846 0.154
E56.1 Deficiency of vitamin K
0.000 0.849 0.151
E26.9 Hyperaldosteronism, unspecified
0.000 0.849 0.151
E26.8 Other hyperaldosteronism
0.000 0.849 0.151
E26.1 Secondary hyperaldosteronism
0.000 0.849 0.151
E51.2 Wernicke's encephalopathy
0.000 0.849 0.150
E61.9 Deficiency of nutrient element, unspecified
0.000 0.852 0.148
E61.8 Deficiency of other specified nutrient elements
0.000 0.852 0.148
E61.7 Deficiency of multiple nutrient elements
0.000 0.852 0.148
E61.6 Vanadium deficiency
0.000 0.852 0.148
E61.5 Molybdenum deficiency
0.000 0.852 0.148
E61.4 Chromium deficiency
0.000 0.852 0.148
E61.3 Manganese deficiency
0.000 0.852 0.148
E61.0 Copper deficiency
0.000 0.852 0.148
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.854 0.146
M06.38 Rheumatoid nodule (Other)
0.000 0.854 0.146
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.854 0.146
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.854 0.146
M06.33 Rheumatoid nodule (Forearm)
0.000 0.854 0.146
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.854 0.146
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.855 0.145
E61.1 Iron deficiency
0.000 0.858 0.142
E61.2 Magnesium deficiency
0.000 0.860 0.139
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.861 0.139
E26.0 Primary hyperaldosteronism
0.000 0.862 0.137
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.867 0.132
E20.8 Other hypoparathyroidism
0.000 0.868 0.131
E20.1 Pseudohypoparathyroidism
0.000 0.868 0.131
E20.0 Idiopathic hypoparathyroidism
0.000 0.868 0.131
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.876 0.124
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.876 0.124
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.876 0.124
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.876 0.124
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.876 0.124
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.876 0.124
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.876 0.124
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.876 0.124
E29.9 Testicular dysfunction, unspecified
0.000 0.876 0.124
E29.8 Other testicular dysfunction
0.000 0.876 0.124
E29.0 Testicular hyperfunction
0.000 0.876 0.124
E89.0 Postprocedural hypothyroidism
0.000 0.877 0.123
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.879 0.121
M06.18 Adult-onset Still's disease (Other)
0.000 0.879 0.121
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.879 0.121
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.879 0.121
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.879 0.121
M06.14 Adult-onset Still's disease (Hand)
0.000 0.879 0.121
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.879 0.121
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.879 0.121
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.879 0.121
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.879 0.121
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.879 0.121
M06.28 Rheumatoid bursitis (Other)
0.000 0.879 0.121
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.879 0.121
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.879 0.121
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.879 0.121
M06.24 Rheumatoid bursitis (Hand)
0.000 0.879 0.121
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.879 0.121
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.879 0.121
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.879 0.121
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.879 0.121
M06.0 Seronegative rheumatoid arthritis
0.000 0.880 0.120
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.881 0.119
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.881 0.119
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.881 0.119
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.881 0.119
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.881 0.119
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.881 0.119
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.881 0.119
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.881 0.119
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.881 0.119
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.885 0.115
C83 Diffuse non-Hodgkin's lymphoma
0.007 0.885 0.108
E55.0 Rickets, active
0.000 0.886 0.114
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.889 0.110
E22.8 Other hyperfunction of pituitary gland
0.000 0.889 0.110
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.890 0.109
K91.4 Colostomy and enterostomy malfunction
0.105 0.895 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.895 0.104

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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