TreeWAS – Variant ID: rs13015993

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.2 Non-toxic multinodular goitre	0.000	0.074	0.926
E04 Other non-toxic goitre	0.000	0.205	0.795
E04.9 Non-toxic goitre, unspecified	0.000	0.227	0.773
E89.0 Postprocedural hypothyroidism	0.000	0.237	0.763
E04.8 Other specified non-toxic goitre	0.000	0.430	0.570
E04.0 Non-toxic diffuse goitre	0.000	0.496	0.504
E00-E07 Disorders of thyroid gland	0.000	0.531	0.469
E06 Thyroiditis	0.000	0.554	0.446
E06.9 Thyroiditis, unspecified	0.000	0.578	0.422
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.581	0.419
E89.2 Postprocedural hypoparathyroidism	0.000	0.643	0.357
E06.5 Other chronic thyroiditis	0.000	0.653	0.346
E06.3 Autoimmune thyroiditis	0.000	0.654	0.346
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.664	0.336
E00 Congenital iodine-deficiency syndrome	0.000	0.664	0.336
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.664	0.336
E89.3 Postprocedural hypopituitarism	0.000	0.671	0.329
E06.4 Drug-induced thyroiditis	0.000	0.680	0.320
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.680	0.320
E06.0 Acute thyroiditis	0.000	0.680	0.320
E06.1 Subacute thyroiditis	0.000	0.689	0.311
E04.1 Non-toxic single thyroid nodule	0.000	0.692	0.308
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.700	0.300
E89.4 Postprocedural ovarian failure	0.000	0.704	0.296
E89.5 Postprocedural testicular hypofunction	0.000	0.712	0.288
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.714	0.286
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.719	0.281
E89.1 Postprocedural hypoinsulinaemia	0.000	0.733	0.266
E07 Other disorders of thyroid	0.000	0.741	0.259
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.743	0.257
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.749	0.251
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.759	0.241
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.759	0.241
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.759	0.241
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.759	0.241
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.759	0.241
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.759	0.241
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.759	0.241
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.759	0.241
E05.5 Thyroid crisis or storm	0.000	0.794	0.205
E05.4 Thyrotoxicosis factitia	0.000	0.794	0.205
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.794	0.205
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.795	0.204
E03 Other hypothyroidism	0.000	0.797	0.203
E05.8 Other thyrotoxicosis	0.000	0.799	0.201
E07.1 Dyshormogenetic goitre	0.000	0.814	0.186
E07.0 Hypersecretion of calcitonin	0.000	0.814	0.186
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.816	0.184
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.834	0.166
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.835	0.165
E07.8 Other specified disorders of thyroid	0.000	0.839	0.161
E40-E46 Malnutrition	0.000	0.848	0.152
E70-E90 Metabolic disorders	0.000	0.849	0.151
E03.8 Other specified hypothyroidism	0.000	0.851	0.149
E07.9 Disorder of thyroid, unspecified	0.000	0.853	0.147
E03.5 Myxoedema coma	0.000	0.854	0.145
E03.4 Atrophy of thyroid (acquired)	0.000	0.854	0.145
E03.3 Postinfectious hypothyroidism	0.000	0.854	0.145
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.855	0.145
E46 Unspecified protein-energy malnutrition	0.000	0.857	0.143
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.867	0.132
E03.1 Congenital hypothyroidism without goitre	0.000	0.869	0.130
E16 Other disorders of pancreatic internal secretion	0.000	0.870	0.130
E74 Other disorders of carbohydrate metabolism	0.000	0.878	0.122
E16.2 Hypoglycaemia, unspecified	0.000	0.879	0.121
E84 Cystic fibrosis	0.000	0.882	0.118
E70 Disorders of aromatic amino-acid metabolism	0.000	0.883	0.117
E85 Amyloidosis	0.000	0.883	0.117
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.891	0.109
E45 Retarded development following protein-energy malnutrition	0.000	0.891	0.109
E43 Unspecified severe protein-energy malnutrition	0.000	0.891	0.109
E42 Marasmic kwashiorkor	0.000	0.891	0.109
E41 Nutritional marasmus	0.000	0.891	0.109
E40 Kwashiorkor	0.000	0.891	0.109
E72 Other disorders of amino-acid metabolism	0.000	0.891	0.109
E77 Disorders of glycoprotein metabolism	0.000	0.891	0.109
E76 Disorders of glycosaminoglycan metabolism	0.000	0.891	0.109
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.891	0.109
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.891	0.109
E15 Nondiabetic hypoglycaemic coma	0.000	0.896	0.104
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.896	0.104
E79 Disorders of purine and pyrimidine metabolism	0.000	0.900	0.100
E73 Lactose intolerance	0.000	0.901	0.098
E85.9 Amyloidosis, unspecified	0.000	0.902	0.098
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.906	0.094
E84.9 Cystic fibrosis, unspecified	0.000	0.906	0.094
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.906	0.094
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.906	0.094
E16.4 Abnormal secretion of gastrin	0.000	0.906	0.094
E16.3 Increased secretion of glucagon	0.000	0.906	0.094
E70.3 Albinism	0.000	0.907	0.093
E16.1 Other hypoglycaemia	0.000	0.908	0.092
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.912	0.088
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.912	0.088
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.912	0.088
E74.2 Disorders of galactose metabolism	0.000	0.912	0.088
E74.1 Disorders of fructose metabolism	0.000	0.912	0.088
E65-E68 Obesity and other hyperalimentation	0.000	0.913	0.087
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.914	0.085
E85.4 Organ-limited amyloidosis	0.000	0.915	0.085
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.915	0.085
E84.8 Cystic fibrosis with other manifestations	0.000	0.915	0.085
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.915	0.085
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.916	0.084
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.916	0.084
E70.2 Disorders of tyrosine metabolism	0.000	0.916	0.084
E70.1 Other hyperphenylalaninaemias	0.000	0.916	0.084
E70.0 Classical phenylketonuria	0.000	0.916	0.084
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.916	0.084
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.916	0.084
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.916	0.084
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.916	0.084
E74.0 Glycogen storage disease	0.000	0.916	0.084
E85.3 Secondary systemic amyloidosis	0.000	0.916	0.084
E80 Disorders of porphyrin and bilirubin metabolism	0.001	0.919	0.081
E44.1 Mild protein-energy malnutrition	0.000	0.921	0.078
E44.0 Moderate protein-energy malnutrition	0.000	0.921	0.078
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.922	0.078
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.922	0.078
E72.5 Disorders of glycine metabolism	0.000	0.922	0.078
E72.4 Disorders of ornithine metabolism	0.000	0.922	0.078
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.922	0.078
E72.2 Disorders of urea cycle metabolism	0.000	0.922	0.078
E71.3 Disorders of fatty-acid metabolism	0.000	0.922	0.078
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.922	0.078
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.922	0.078
E71.0 Maple-syrup-urine disease	0.000	0.922	0.078
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.922	0.078
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.922	0.078
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.922	0.078
E76.2 Other mucopolysaccharidoses	0.000	0.922	0.078
E76.1 Mucopolysaccharidosis, type II	0.000	0.922	0.078
E76.0 Mucopolysaccharidosis, type I	0.000	0.922	0.078
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.922	0.078
E77.8 Other disorders of glycoprotein metabolism	0.000	0.922	0.078
E77.1 Defects in glycoprotein degradation	0.000	0.922	0.078
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.922	0.078
E85.8 Other amyloidosis	0.000	0.925	0.075
E50-E64 Other nutritional deficiencies	0.000	0.926	0.074
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.928	0.072
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.928	0.072
E79.1 Lesch-Nyhan syndrome	0.000	0.928	0.072
E72.0 Disorders of amino-acid transport	0.000	0.929	0.071
E73.8 Other lactose intolerance	0.000	0.929	0.071
E73.1 Secondary lactase deficiency	0.000	0.929	0.071
E73.0 Congenital lactase deficiency	0.000	0.929	0.071
E80.2 Other porphyria	0.000	0.930	0.070
E05.9 Thyrotoxicosis, unspecified	0.000	0.934	0.066
E65 Localised adiposity	0.000	0.935	0.065
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.936	0.063
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.937	0.063
E67 Other hyperalimentation	0.000	0.938	0.062
E68 Sequelae of hyperalimentation	0.000	0.938	0.062
E75.6 Lipid storage disorder, unspecified	0.000	0.938	0.061
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.938	0.061
E75.3 Sphingolipidosis, unspecified	0.000	0.938	0.061
E75.1 Other gangliosidosis	0.000	0.938	0.061
E75.0 GM2 gangliosidosis	0.000	0.938	0.061
E73.9 Lactose intolerance, unspecified	0.000	0.939	0.061
E54 Ascorbic acid deficiency	0.000	0.941	0.059
E80.5 Crigler-Najjar syndrome	0.001	0.941	0.058
E80.3 Defects of catalase and peroxydase	0.001	0.941	0.058
E80.0 Hereditary erythropoietic porphyria	0.001	0.941	0.058
E55 Vitamin D deficiency	0.000	0.942	0.058
E80.1 Porphyria cutanea tarda	0.001	0.944	0.056
E75.2 Other sphingolipidosis	0.000	0.944	0.056
E63 Other nutritional deficiencies	0.000	0.945	0.055
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.947	0.053
E50 Vitamin A deficiency	0.000	0.947	0.053
E60 Dietary zinc deficiency	0.000	0.947	0.053
E59 Dietary selenium deficiency	0.000	0.947	0.053
E52 Niacin deficiency [pellagra]	0.000	0.947	0.053
E51 Thiamine deficiency	0.000	0.948	0.052
E56 Other vitamin deficiencies	0.000	0.949	0.051
E88 Other metabolic disorders	0.000	0.950	0.049
E75.5 Other lipid storage disorders	0.001	0.953	0.047
E55.9 Vitamin D deficiency, unspecified	0.000	0.954	0.046
E80.6 Other disorders of bilirubin metabolism	0.001	0.955	0.044
E67.8 Other specified hyperalimentation	0.000	0.955	0.045
E67.3 Hypervitaminosis D	0.000	0.955	0.045
E67.2 Megavitamin-B6 syndrome	0.000	0.955	0.045
E67.1 Hypercarotenaemia	0.000	0.955	0.045
E67.0 Hypervitaminosis A	0.000	0.955	0.045
E55.0 Rickets, active	0.000	0.958	0.042
E63.9 Nutritional deficiency, unspecified	0.000	0.959	0.041
E58 Dietary calcium deficiency	0.000	0.959	0.041
E53 Deficiency of other B group vitamins	0.000	0.959	0.040
E63.8 Other specified nutritional deficiencies	0.000	0.960	0.040
E63.1 Imbalance of constituents of food intake	0.000	0.960	0.040
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.960	0.040
E50.9 Vitamin A deficiency, unspecified	0.000	0.961	0.038
E50.8 Other manifestations of vitamin A deficiency	0.000	0.961	0.038
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.961	0.038
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.961	0.038
E50.5 Vitamin A deficiency with night blindness	0.000	0.961	0.038
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.961	0.038
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.961	0.038
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.961	0.038
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.961	0.038
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.961	0.038
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.961	0.038
E64.8 Sequelae of other nutritional deficiencies	0.000	0.961	0.038
E64.3 Sequelae of rickets	0.000	0.961	0.038
E64.2 Sequelae of vitamin C deficiency	0.000	0.961	0.038
E64.1 Sequelae of vitamin A deficiency	0.000	0.961	0.038
E64.0 Sequelae of protein-energy malnutrition	0.000	0.961	0.038
E88.3 Tumour lysis syndrome	0.000	0.962	0.038
E51.9 Thiamine deficiency, unspecified	0.000	0.963	0.037
E51.8 Other manifestations of thiamine deficiency	0.000	0.963	0.037
E51.1 Beriberi	0.000	0.963	0.037
E56.9 Vitamin deficiency, unspecified	0.000	0.963	0.037
E56.8 Deficiency of other vitamins	0.000	0.963	0.037
E56.0 Deficiency of vitamin E	0.000	0.963	0.037
E51.2 Wernicke's encephalopathy	0.000	0.964	0.035
E88.2 Lipomatosis, not elsewhere classified	0.000	0.964	0.035
E56.1 Deficiency of vitamin K	0.000	0.965	0.035
E88.9 Metabolic disorder, unspecified	0.000	0.966	0.034
E61 Deficiency of other nutrient elements	0.000	0.966	0.034
E53.9 Vitamin B deficiency, unspecified	0.000	0.967	0.033
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.970	0.029
E53.1 Pyridoxine deficiency	0.000	0.971	0.029
E53.0 Riboflavin deficiency	0.000	0.971	0.029
E88.8 Other specified metabolic disorders	0.001	0.973	0.027
E61.9 Deficiency of nutrient element, unspecified	0.000	0.975	0.024
E61.8 Deficiency of other specified nutrient elements	0.000	0.975	0.024
E61.7 Deficiency of multiple nutrient elements	0.000	0.975	0.024
E61.6 Vanadium deficiency	0.000	0.975	0.024
E61.5 Molybdenum deficiency	0.000	0.975	0.024
E61.4 Chromium deficiency	0.000	0.975	0.024
E61.3 Manganese deficiency	0.000	0.975	0.024
E61.0 Copper deficiency	0.000	0.975	0.024
E66 Obesity	0.000	0.976	0.024
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.978	0.022
E66.1 Drug-induced obesity	0.000	0.982	0.017
E61.2 Magnesium deficiency	0.001	0.982	0.017
E61.1 Iron deficiency	0.000	0.983	0.017
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.983	0.016
Z01.8 Other specified special examinations	0.016	0.984	0.000
E66.0 Obesity due to excess calories	0.000	0.984	0.015
E10-E14 Diabetes mellitus	0.000	0.986	0.014
E86 Volume depletion	0.000	0.986	0.014
E20-E35 Disorders of other endocrine glands	0.000	0.986	0.014
O61.0 Failed medical induction of labour	0.000	0.987	0.013
J36 Peritonsillar abscess	0.000	0.989	0.011
E22 Hyperfunction of pituitary gland	0.000	0.990	0.010
E32 Diseases of thymus	0.000	0.990	0.010
E12 Malnutrition-related diabetes mellitus	0.000	0.990	0.010
E80.4 Gilbert's syndrome	0.002	0.990	0.009
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.990	0.010
E30 Disorders of puberty, not elsewhere classified	0.000	0.990	0.010
G57.6 Lesion of plantar nerve	0.000	0.990	0.010
E31 Polyglandular dysfunction	0.000	0.990	0.010
E34 Other endocrine disorders	0.000	0.991	0.009
E25 Adrenogenital disorders	0.000	0.991	0.009
E26 Hyperaldosteronism	0.000	0.991	0.009
E22.1 Hyperprolactinaemia	0.000	0.991	0.009
E24 Cushing's syndrome	0.000	0.991	0.009
E13 Other specified diabetes mellitus	0.000	0.991	0.008
K92.0 Haematemesis	0.009	0.991	0.000
E20 Hypoparathyroidism	0.000	0.991	0.008
E29 Testicular dysfunction	0.000	0.992	0.008
E32.9 Disease of thymus, unspecified	0.000	0.992	0.008
E83 Disorders of mineral metabolism	0.000	0.992	0.008
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.992	0.008
E28 Ovarian dysfunction	0.000	0.992	0.008
E22.8 Other hyperfunction of pituitary gland	0.000	0.992	0.008
E32.8 Other diseases of thymus	0.000	0.992	0.008
E32.1 Abscess of thymus	0.000	0.992	0.008
E32.0 Persistent hyperplasia of thymus	0.000	0.992	0.008
E12.9 Without complications	0.000	0.992	0.008
E12.8 With unspecified complications	0.000	0.992	0.008
E12.7 With multiple complications	0.000	0.992	0.008
E12.6 With other specified complications	0.000	0.992	0.008
E12.5 With peripheral circulatory complications	0.000	0.992	0.008
E12.4 With neurological complications	0.000	0.992	0.008
E12.3 With ophthalmic complications	0.000	0.992	0.008
E12.2 With renal complications	0.000	0.992	0.008
E12.1 With ketoacidosis	0.000	0.992	0.008
E12.0 With coma	0.000	0.992	0.008
E27 Other disorders of adrenal gland	0.000	0.992	0.008
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.993	0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.993	0.007
E30.9 Disorder of puberty, unspecified	0.000	0.993	0.007
E30.8 Other disorders of puberty	0.000	0.993	0.007
E30.1 Precocious puberty	0.000	0.993	0.007
E30.0 Delayed puberty	0.000	0.993	0.007
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.993	0.007
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.993	0.007
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.993	0.007
E22.0 Acromegaly and pituitary gigantism	0.000	0.993	0.007
E31.9 Polyglandular dysfunction, unspecified	0.000	0.993	0.007
E31.8 Other polyglandular dysfunction	0.000	0.993	0.007
E31.1 Polyglandular hyperfunction	0.000	0.993	0.007
E34.3 Short stature, not elsewhere classified	0.000	0.993	0.007
E31.0 Autoimmune polyglandular failure	0.000	0.993	0.007
E34.5 Androgen resistance syndrome	0.000	0.993	0.007
E34.4 Constitutional tall stature	0.000	0.993	0.007
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.993	0.007
E34.1 Other hypersecretion of intestinal hormones	0.000	0.993	0.007
E34.0 Carcinoid syndrome	0.000	0.993	0.007
E25.9 Adrenogenital disorder, unspecified	0.000	0.993	0.007
E25.8 Other adrenogenital disorders	0.000	0.993	0.007
E23 Hypofunction and other disorders of pituitary gland	0.000	0.993	0.007
E26.8 Other hyperaldosteronism	0.000	0.993	0.007
E26.1 Secondary hyperaldosteronism	0.000	0.993	0.007
E24.8 Other Cushing's syndrome	0.000	0.993	0.007
E24.2 Drug-induced Cushing's syndrome	0.000	0.993	0.007
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.993	0.007
E34.8 Other specified endocrine disorders	0.000	0.993	0.006
E26.9 Hyperaldosteronism, unspecified	0.000	0.993	0.006
N20.1 Calculus of ureter	0.000	0.993	0.007
E29.9 Testicular dysfunction, unspecified	0.000	0.993	0.006
E34.9 Endocrine disorder, unspecified	0.000	0.993	0.006
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.993	0.006
E24.3 Ectopic ACTH syndrome	0.000	0.993	0.006
E24.1 Nelson's syndrome	0.000	0.993	0.006
E13.8 With unspecified complications	0.000	0.994	0.006
E13.7 With multiple complications	0.000	0.994	0.006
E13.6 With other specified complications	0.000	0.994	0.006
E13.5 With peripheral circulatory complications	0.000	0.994	0.006
E13.4 With neurological complications	0.000	0.994	0.006
E13.3 With ophthalmic complications	0.000	0.994	0.006
E13.2 With renal complications	0.000	0.994	0.006
E13.1 With ketoacidosis	0.000	0.994	0.006
E13.0 With coma	0.000	0.994	0.006
E20.8 Other hypoparathyroidism	0.000	0.994	0.006
E20.0 Idiopathic hypoparathyroidism	0.000	0.994	0.006
E10.1 With ketoacidosis	0.000	0.994	0.006
E20.1 Pseudohypoparathyroidism	0.000	0.994	0.006
E29.8 Other testicular dysfunction	0.000	0.994	0.006
E29.0 Testicular hyperfunction	0.000	0.994	0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.994	0.006
E28.2 Polycystic ovarian syndrome	0.000	0.994	0.006
E26.0 Primary hyperaldosteronism	0.000	0.994	0.006
C34.1 Upper lobe, bronchus or lung	0.000	0.994	0.006
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.994	0.000
E83.8 Other disorders of mineral metabolism	0.000	0.994	0.006
E83.2 Disorders of zinc metabolism	0.000	0.994	0.006
E83.0 Disorders of copper metabolism	0.000	0.994	0.006
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.000	0.994	0.006
E28.9 Ovarian dysfunction, unspecified	0.000	0.994	0.006
E28.8 Other ovarian dysfunction	0.000	0.994	0.006
E28.1 Androgen excess	0.000	0.994	0.006
E28.0 Oestrogen excess	0.000	0.994	0.006
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.994	0.006
E53.8 Deficiency of other specified B group vitamins	0.000	0.994	0.006
O61 Failed induction of labour	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.006
E27.0 Other adrenocortical overactivity	0.000	0.994	0.006
E24.0 Pituitary-dependent Cushing's disease	0.000	0.994	0.005
E23.2 Diabetes insipidus	0.000	0.994	0.006
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.994	0.006
O26.9 Pregnancy-related condition, unspecified	0.006	0.994	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.994	0.005
A41.9 Septicaemia, unspecified	0.006	0.994	0.000
E10.2 With renal complications	0.000	0.994	0.005
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
E23.6 Other disorders of pituitary gland	0.000	0.995	0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.995	0.005
E23.1 Drug-induced hypopituitarism	0.000	0.995	0.005
E20.9 Hypoparathyroidism, unspecified	0.000	0.995	0.005
J39.2 Other diseases of pharynx	0.005	0.995	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.995	0.005
E10.0 With coma	0.000	0.995	0.005
E10.7 With multiple complications	0.000	0.995	0.005
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.995	0.005
E27.8 Other specified disorders of adrenal gland	0.000	0.995	0.005
E21.2 Other hyperparathyroidism	0.000	0.995	0.005
G57.8 Other mononeuropathies of lower limb	0.000	0.995	0.005
O61.9 Failed induction of labour, unspecified	0.000	0.995	0.004
K72.9 Hepatic failure, unspecified	0.000	0.995	0.005
E78.4 Other hyperlipidaemia	0.000	0.995	0.005
L73.9 Follicular disorder, unspecified	0.000	0.995	0.005
E13.9 Without complications	0.000	0.995	0.004
E27.1 Primary adrenocortical insufficiency	0.000	0.995	0.004
G57 Mononeuropathies of lower limb	0.000	0.995	0.004
O61.8 Other failed induction of labour	0.000	0.996	0.004
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.004
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.996	0.004
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.996	0.004
O61.1 Failed instrumental induction of labour	0.000	0.996	0.004
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.996	0.004
E21.4 Other specified disorders of parathyroid gland	0.000	0.996	0.004
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.996	0.004
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.004	0.996	0.000
E10.6 With other specified complications	0.000	0.996	0.004
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.996	0.004
E23.7 Disorder of pituitary gland, unspecified	0.000	0.996	0.004
E29.1 Testicular hypofunction	0.000	0.996	0.004
E78.2 Mixed hyperlipidaemia	0.000	0.996	0.004
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.996	0.004
G82.1 Spastic paraplegia	0.000	0.996	0.004
Z01.6 Radiological examination, not elsewhere classified	0.004	0.996	0.000
E78.6 Lipoprotein deficiency	0.000	0.996	0.004
E83.1 Disorders of iron metabolism	0.000	0.996	0.004
M70.6 Trochanteric bursitis	0.000	0.996	0.004
E28.3 Primary ovarian failure	0.001	0.996	0.003
G57.3 Lesion of lateral popliteal nerve	0.000	0.996	0.004
E78.3 Hyperchylomicronaemia	0.000	0.996	0.003
U80.1 Methicillin resistant agent	0.000	0.996	0.004
Z01.2 Dental examination	0.004	0.996	0.000
G57.4 Lesion of medial popliteal nerve	0.000	0.996	0.003
G57.2 Lesion of femoral nerve	0.000	0.996	0.003
O20.0 Threatened abortion	0.004	0.996	0.000
G57.0 Lesion of sciatic nerve	0.000	0.997	0.003
I80 Phlebitis and thrombophlebitis	0.000	0.997	0.003
Z01.0 Examination of eyes and vision	0.003	0.997	0.000
Z01.1 Examination of ears and hearing	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.000	0.997	0.003
E87.4 Mixed disorder of acid-base balance	0.000	0.997	0.003
U89 Agent resistant to other and unspecified antibiotics	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.997	0.003
Z01.4 Gynaecological examination (general)(routine)	0.003	0.997	0.000
G57.5 Tarsal tunnel syndrome	0.000	0.997	0.003
E10.9 Without complications	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
K72 Hepatic failure, not elsewhere classified	0.000	0.997	0.003
E87.7 Fluid overload	0.000	0.997	0.003
M79.66 Pain in limb (Lower leg)	0.000	0.997	0.003
S01.8 Open wound of other parts of head	0.003	0.997	0.000
Z01.3 Examination of blood pressure	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.000	0.997	0.003
G24.9 Dystonia, unspecified	0.003	0.997	0.000
G24.5 Blepharospasm	0.003	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.003	0.997	0.000
E11.1 With ketoacidosis	0.000	0.997	0.003
M70.68 Trochanteric bursitis-Other	0.000	0.997	0.003
M70.67 Trochanteric bursitis-Ankle/Foot	0.000	0.997	0.003
M70.66 Trochanteric bursitis-Lower Leg	0.000	0.997	0.003
M70.64 Trochanteric bursitis-Hand	0.000	0.997	0.003
M70.63 Trochanteric bursitis-Forearm	0.000	0.997	0.003
M70.62 Trochanteric bursitis-Upper arm	0.000	0.997	0.003
M70.61 Trochanteric bursitis-Shldr region	0.000	0.997	0.003
M70.60 Trochanteric bursitis-Mult sites	0.000	0.997	0.003
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.997	0.003
K72.1 Chronic hepatic failure	0.000	0.997	0.003
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
E10.8 With unspecified complications	0.001	0.997	0.002
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.003
Z01.5 Diagnostic skin and sensitisation tests	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.000	0.997	0.003
R57.2 Septic shock	0.003	0.997	0.000
M70.69 Trochanteric bursitis-Site unspec	0.000	0.997	0.003
G24 Dystonia	0.003	0.997	0.000
G82 Paraplegia and tetraplegia	0.000	0.997	0.003
E83.3 Disorders of phosphorus metabolism	0.000	0.997	0.002
D62 Acute posthaemorrhagic anaemia	0.000	0.997	0.003
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.997	0.003
E78.1 Pure hyperglyceridaemia	0.000	0.997	0.002
U89.9 Agent resistant to unspecified antibiotic	0.000	0.997	0.002
N20 Calculus of kidney and ureter	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.000	0.997	0.003
O36.6 Maternal care for excessive foetal growth	0.000	0.997	0.003
G24.8 Other dystonia	0.002	0.997	0.000
E87.3 Alkalosis	0.000	0.997	0.002
N20.0 Calculus of kidney	0.000	0.997	0.003
S32.40 Fracture of acetabulum (closed)	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
Z01.7 Laboratory examination	0.002	0.998	0.000
J39 Other diseases of upper respiratory tract	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.000	0.998	0.002
C53.0 Endocervix	0.000	0.998	0.002
G57.1 Meralgia paraesthetica	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
C53 Malignant neoplasm of cervix uteri	0.000	0.998	0.002
G24.3 Spasmodic torticollis	0.002	0.998	0.000
G24.0 Drug-induced dystonia	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
Z94.8 Other transplanted organ and tissue status	0.002	0.998	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.998	0.002
N20.9 Urinary calculus, unspecified	0.000	0.998	0.002
E11 Non-insulin-dependent diabetes mellitus	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
M25.54 Pain in joint (Hand)	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.998	0.002
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
E10.4 With neurological complications	0.001	0.998	0.001
E78.8 Other disorders of lipoprotein metabolism	0.001	0.998	0.001
A41 Other septicaemia	0.002	0.998	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.002
J35.1 Hypertrophy of tonsils	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations