TreeWAS – Variant ID: rs13038031

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
I70-I79 Diseases of arteries, arterioles and capillaries	0.990	0.010
I60-I69 Cerebrovascular diseases	0.987	0.013
I10-I15 Hypertensive diseases	0.981	0.019
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.979	0.021
S40-S49 Injuries to the shoulder and upper arm	0.976	0.024
I63 Cerebral infarction	0.965	0.035
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.962	0.038
I10 Essential (primary) hypertension	0.960	0.040
T20-T25 Burns and corrosions of external body surface, specified by site	0.959	0.041
D50-D53 Nutritional anaemias	0.956	0.044
S50-S59 Injuries to the elbow and forearm	0.941	0.059
I20-I25 Ischaemic heart diseases	0.938	0.062
D60-D64 Aplastic and other anaemias	0.937	0.063
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.934	0.066
T46 Poisoning by agents primarily affecting the cardiovascular system	0.931	0.069
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.924	0.076
Chapter VI Diseases of the nervous system	0.923	0.077
T42.4 Benzodiazepines	0.922	0.078
I69 Sequelae of cerebrovascular disease	0.913	0.087
Chapter V Mental and behavioural disorders	0.906	0.094
S52 Fracture of forearm	0.904	0.096
T15-T19 Effects of foreign body entering through natural orifice	0.901	0.099
I25 Chronic ischaemic heart disease	0.901	0.099
D52 Folate deficiency anaemia	0.900	0.100
I71 Aortic aneurysm and dissection	0.900	0.100
D80-D89 Certain disorders involving the immune mechanism	0.900	0.100
I73 Other peripheral vascular diseases	0.896	0.104
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.896	0.104
I77 Other disorders of arteries and arterioles	0.895	0.105
G40-G47 Episodic and paroxysmal disorders	0.895	0.105
S42 Fracture of shoulder and upper arm	0.891	0.109
T40.2 Other opioids	0.890	0.110
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.887	0.113
T20 Burn and corrosion of head and neck	0.885	0.115
I25.9 Chronic ischaemic heart disease, unspecified	0.881	0.119
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.874	0.126
Chapter IV Endocrine, nutritional and metabolic diseases	0.872	0.128
S52.5 Fracture of lower end of radius	0.870	0.130
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.869	0.131
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.869	0.131
I73.9 Peripheral vascular disease, unspecified	0.869	0.131
G40 Epilepsy	0.865	0.135
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.865	0.135
D63 Anaemia in chronic diseases classified elsewhere	0.864	0.136
I05-I09 Chronic rheumatic heart diseases	0.862	0.138
D52.9 Folate deficiency anaemia, unspecified	0.860	0.140
I20 Angina pectoris	0.855	0.145
I77.1 Stricture of artery	0.854	0.146
I63.8 Other cerebral infarction	0.854	0.146
I74 Arterial embolism and thrombosis	0.852	0.148
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.851	0.149
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.850	0.150
G20-G26 Extrapyramidal and movement disorders	0.849	0.151
T18 Foreign body in alimentary tract	0.848	0.152
T46.4 Angiotensin-converting-enzyme inhibitors	0.847	0.153
I67 Other cerebrovascular diseases	0.844	0.156
S52.50 Fracture of lower end of radius (closed)	0.843	0.157
M20-M25 Other joint disorders	0.842	0.158
E20-E35 Disorders of other endocrine glands	0.839	0.161
D50 Iron deficiency anaemia	0.839	0.161
I20.8 Other forms of angina pectoris	0.839	0.161
S42.2 Fracture of upper end of humerus	0.836	0.164
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.836	0.164
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.836	0.164
G25 Other extrapyramidal and movement disorders	0.832	0.168
D63.0 Anaemia in neoplastic disease	0.831	0.169
S10-S19 Injuries to the neck	0.826	0.174
T43.3 Phenothiazine antipsychotics and neuroleptics	0.825	0.175
D64 Other anaemias	0.824	0.176
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.821	0.179
T43.0 Tricyclic and tetracyclic antidepressants	0.815	0.185
D68 Other coagulation defects	0.813	0.187
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.812	0.188
G25.8 Other specified extrapyramidal and movement disorders	0.812	0.188
S43.0 Dislocation of shoulder joint	0.810	0.190
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.810	0.190
I25.8 Other forms of chronic ischaemic heart disease	0.809	0.191
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.807	0.193
I07 Rheumatic tricuspid valve diseases	0.807	0.193
G45 Transient cerebral ischaemic attacks and related syndromes	0.805	0.195
M21 Other acquired deformities of limbs	0.803	0.197
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.801	0.199
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.800	0.200
T18.1 Foreign body in oesophagus	0.799	0.201
F30-F39 Mood [affective] disorders	0.799	0.201
T43.5 Other and unspecified antipsychotics and neuroleptics	0.797	0.203
S42.20 Fracture of upper end of humerus (closed)	0.797	0.203
I15 Secondary hypertension	0.796	0.204
T43.2 Other and unspecified antidepressants	0.793	0.207
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.792	0.208
T00-T07 Injuries involving multiple body regions	0.791	0.209
I95-I99 Other and unspecified disorders of the circulatory system	0.790	0.210
I71.3 Abdominal aortic aneurysm, ruptured	0.789	0.211
Chapter XII Diseases of the skin and subcutaneous tissue	0.789	0.211
S56 Injury of muscle and tendon at forearm level	0.786	0.214
D50.9 Iron deficiency anaemia, unspecified	0.785	0.215
T39.1 4-Aminophenol derivatives	0.784	0.216
G40.9 Epilepsy, unspecified	0.784	0.216
M86-M90 Other osteopathies	0.782	0.218
M25 Other joint disorders, not elsewhere classified	0.779	0.221
T50.9 Other and unspecified drugs, medicaments and biological substances	0.775	0.225
I61 Intracerebral haemorrhage	0.774	0.226
T36 Poisoning by systemic antibiotics	0.769	0.231
I62 Other nontraumatic intracranial haemorrhage	0.768	0.232
L40-L45 Papulosquamous disorders	0.768	0.232
I07.1 Tricuspid insufficiency	0.767	0.233
S41 Open wound of shoulder and upper arm	0.767	0.233
E21.0 Primary hyperparathyroidism	0.766	0.234
M24 Other specific joint derangements	0.764	0.236
S40 Superficial injury of shoulder and upper arm	0.764	0.236
G00-G09 Inflammatory diseases of the central nervous system	0.763	0.237
L43 Lichen planus	0.763	0.237
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.763	0.237
L43.9 Lichen planus, unspecified	0.760	0.240
T20.2 Burn of second degree of head and neck	0.760	0.240
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.759	0.241
G30-G32 Other degenerative diseases of the nervous system	0.759	0.241
I11 Hypertensive heart disease	0.752	0.248
G40.5 Special epileptic syndromes	0.751	0.248
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.751	0.249
M25.5 Pain in joint	0.750	0.250
I67.9 Cerebrovascular disease, unspecified	0.748	0.252
D64.9 Anaemia, unspecified	0.742	0.258
T46.5 Other antihypertensive drugs, not elsewhere classified	0.742	0.258
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.742	0.258
D68.2 Hereditary deficiency of other clotting factors	0.741	0.259
M60-M63 Disorders of muscles	0.738	0.262
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.737	0.263
S70-S79 Injuries to the hip and thigh	0.737	0.263
T39.0 Salicylates	0.735	0.265
M25.56 Pain in joint (Lower leg)	0.733	0.267
T20.0 Burn of unspecified degree of head and neck	0.732	0.267
M21.3 Wrist or foot drop (acquired)	0.732	0.268
T23 Burn and corrosion of wrist and hand	0.729	0.271
D89.2 Hypergammaglobulinaemia, unspecified	0.728	0.272
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.727	0.272
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.727	0.273
E50-E64 Other nutritional deficiencies	0.726	0.274
T42.1 Iminostilbenes	0.725	0.275
G70-G73 Diseases of myoneural junction and muscle	0.723	0.277
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.717	0.283
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
S52.0 Fracture of upper end of ulna	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
S52.1 Fracture of upper end of radius	0.717	0.283
F80-F89 Disorders of psychological development	0.717	0.283
S49 Other and unspecified injuries of shoulder and upper arm	0.716	0.284
G41 Status epilepticus	0.716	0.284
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.715	0.285
G45.4 Transient global amnesia	0.713	0.287
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.712	0.288
M90 Osteopathies in diseases classified elsewhere	0.711	0.289
T20.1 Burn of first degree of head and neck	0.710	0.289
Q60-Q64 Congenital malformations of the urinary system	0.710	0.290
T21 Burn and corrosion of trunk	0.710	0.290
D53 Other nutritional anaemias	0.708	0.292
F31 Bipolar affective disorder	0.708	0.292
I68 Cerebrovascular disorders in diseases classified elsewhere	0.708	0.292
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.708	0.292
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.707	0.293
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.707	0.293
Chapter XXII Codes for special purposes	0.705	0.295
I13 Hypertensive heart and renal disease	0.703	0.297
Q38-Q45 Other congenital malformations of the digestive system	0.703	0.297
G25.3 Myoclonus	0.702	0.298
I67.0 Dissection of cerebral arteries, nonruptured	0.702	0.298
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.702	0.298
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.702	0.298
T42.5 Mixed antiepileptics, not elsewhere classified	0.702	0.298
T42.3 Barbiturates	0.702	0.298
T42.2 Succinimides and oxazolidinediones	0.702	0.298
T42.0 Hydantoin derivatives	0.702	0.298
S19 Other and unspecified injuries of neck	0.701	0.299
F99-F99 Unspecified mental disorder	0.701	0.299
D84 Other immunodeficiencies	0.701	0.299
M21.2 Flexion deformity	0.700	0.300
S48 Traumatic amputation of shoulder and upper arm	0.699	0.300
S45 Injury of blood vessels at shoulder and upper arm level	0.699	0.300
S44 Injury of nerves at shoulder and upper arm level	0.699	0.300
S47 Crushing injury of shoulder and upper arm	0.699	0.300
E23 Hypofunction and other disorders of pituitary gland	0.698	0.302
Chapter XXI Factors influencing health status and contact with health services	0.697	0.303
D68.0 Von Willebrand's disease	0.697	0.303
I69.0 Sequelae of subarachnoid haemorrhage	0.696	0.304
Z70-Z76 Persons encountering health services in other circumstances	0.695	0.305
G46 Vascular syndromes of brain in cerebrovascular diseases	0.695	0.305
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.694	0.306
I73.8 Other specified peripheral vascular diseases	0.694	0.306
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.693	0.307
I78 Diseases of capillaries	0.692	0.308
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.692	0.308
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.692	0.308
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.692	0.308
S46 Injury of muscle and tendon at shoulder and upper arm level	0.692	0.308
T43.9 Psychotropic drug, unspecified	0.689	0.310
T43.8 Other psychotropic drugs, not elsewhere classified	0.689	0.310
T43.6 Psychostimulants with abuse potential	0.689	0.310
T43.4 Butyrophenone and thioxanthene neuroleptics	0.689	0.310
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.689	0.310
T25 Burn and corrosion of ankle and foot	0.688	0.312
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.688	0.312
F25 Schizoaffective disorders	0.687	0.313
D62 Acute posthaemorrhagic anaemia	0.687	0.313
D55-D59 Haemolytic anaemias	0.687	0.313
Z75 Problems related to medical facilities and other health care	0.686	0.314
G40.8 Other epilepsy	0.686	0.314
T92 Sequelae of injuries of upper limb	0.685	0.315
D68.6 Other Thrombophilia	0.685	0.315
M33 Dermatopolymyositis	0.684	0.316
F60-F69 Disorders of adult personality and behaviour	0.684	0.316
G44 Other headache syndromes	0.684	0.316
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.682	0.318
I20.0 Unstable angina	0.681	0.319
S52.8 Fracture of other parts of forearm	0.678	0.322
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.674	0.325
S59 Other and unspecified injuries of forearm	0.674	0.325
S58 Traumatic amputation of forearm	0.674	0.325
S57 Crushing injury of forearm	0.674	0.325
S55 Injury of blood vessels at forearm level	0.674	0.325
S54 Injury of nerves at forearm level	0.674	0.325
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.674	0.325
T31 Burns classified according to extent of body surface involved	0.674	0.325
S42.4 Fracture of lower end of humerus	0.674	0.326
E22 Hyperfunction of pituitary gland	0.674	0.326
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.673	0.327
I23 Certain current complications following acute myocardial infarction	0.672	0.327
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.672	0.328
M25.3 Other instability of joint	0.672	0.328
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.671	0.329
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.669	0.331
T40.8 Lysergide [LSD]	0.669	0.331
T40.7 Cannabis (derivatives)	0.669	0.331
T40.6 Other and unspecified narcotics	0.669	0.331
T40.5 Cocaine	0.669	0.331
T40.3 Methadone	0.669	0.331
T40.1 Heroin	0.669	0.331
T40.0 Opium	0.669	0.331
I70 Atherosclerosis	0.669	0.331
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.667	0.333
T46.8 Antivaricose drugs, including sclerosing agents	0.667	0.333
T46.7 Peripheral vasodilators	0.667	0.333
T46.3 Coronary vasodilators, not elsewhere classified	0.667	0.333
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.667	0.333
T46.1 Calcium-channel blockers	0.667	0.333
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.667	0.333
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.665	0.335
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.665	0.335
S42.7 Multiple fractures of clavicle, scapula and humerus	0.665	0.335
F00-F09 Organic, including symptomatic, mental disorders	0.664	0.336
I72 Other aneurysm	0.664	0.336
M21.1 Varus deformity, not elsewhere classified	0.664	0.336
I15.1 Hypertension secondary to other renal disorders	0.664	0.336
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.663	0.337
T18.9 Foreign body in alimentary tract, part unspecified	0.663	0.337
T39.4 Antirheumatics, not elsewhere classified	0.662	0.337
T39.2 Pyrazolone derivatives	0.662	0.337
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.662	0.338
M24.5 Contracture of joint	0.661	0.339
M90.7 Fracture of bone in neoplastic disease	0.661	0.339
G40.7 Petit mal, unspecified, without grand mal seizures	0.661	0.339
S52.2 Fracture of shaft of ulna	0.661	0.339
I77.8 Other specified disorders of arteries and arterioles	0.661	0.339
I25.5 Ischaemic cardiomyopathy	0.659	0.341
M25.57 Pain in joint (Ankle and foot)	0.657	0.343
M45-M49 Spondylopathies	0.655	0.345
D80 Immunodeficiency with predominantly antibody defects	0.655	0.345
S52.51 Fracture of lower end of radius (open)	0.655	0.345
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.655	0.345
I67.8 Other specified cerebrovascular diseases	0.652	0.348
Z75.1 Person awaiting admission to adequate facility elsewhere	0.651	0.349
I71.0 Dissection of aorta [any part]	0.650	0.350
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.650	0.350
F70-F79 Mental retardation	0.650	0.350
I12 Hypertensive renal disease	0.649	0.351
L57 Skin changes due to chronic exposure to nonionising radiation	0.649	0.351
S52.9 Fracture of forearm, part unspecified	0.648	0.352
S52.7 Multiple fractures of forearm	0.648	0.352
S52.4 Fracture of shafts of both ulna and radius	0.648	0.352
S52.3 Fracture of shaft of radius	0.648	0.352
Q61 Cystic kidney disease	0.647	0.353
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.647	0.353
T19 Foreign body in genito-urinary tract	0.646	0.354
T15 Foreign body on external eye	0.646	0.354
T16 Foreign body in ear	0.646	0.354
I25.6 Silent myocardial ischaemia	0.646	0.354
I25.0 Atherosclerotic cardiovascular disease, so described	0.646	0.354
F22 Persistent delusional disorders	0.646	0.354
D52.8 Other folate deficiency anaemias	0.645	0.354
D52.1 Drug-induced folate deficiency anaemia	0.645	0.354
D52.0 Dietary folate deficiency anaemia	0.645	0.354
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.645	0.354
I71.8 Aortic aneurysm of unspecified site, ruptured	0.645	0.355
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.645	0.355
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.645	0.355
I71.1 Thoracic aortic aneurysm, ruptured	0.645	0.355
T40.4 Other synthetic narcotics	0.645	0.355
D83 Common variable immunodeficiency	0.645	0.355
D82 Immunodeficiency associated with other major defects	0.645	0.355
D81 Combined immunodeficiencies	0.645	0.355
M25.9 Joint disorder, unspecified	0.645	0.355
M34 Systemic sclerosis	0.644	0.356
I73.1 Thromboangiitis obliterans [Buerger]	0.643	0.357
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.642	0.358
I77.5 Necrosis of artery	0.642	0.358
I77.4 Coeliac artery compression syndrome	0.642	0.358
I77.3 Arterial fibromuscular dysplasia	0.642	0.358
I77.2 Rupture of artery	0.642	0.358
T00 Superficial injuries involving multiple body regions	0.642	0.358
Q80-Q89 Other congenital malformations	0.640	0.360
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.639	0.361
M00-M03 Infectious arthropathies	0.639	0.361
D89.9 Disorder involving the immune mechanism, unspecified	0.639	0.361
F31.0 Bipolar affective disorder, current episode hypomanic	0.639	0.361
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.639	0.361
I74.9 Embolism and thrombosis of unspecified artery	0.639	0.361
S42.9 Fracture of shoulder girdle, part unspecified	0.639	0.361
S42.8 Fracture of other parts of shoulder and upper arm	0.639	0.361
I25.4 Coronary artery aneurysm	0.638	0.361
S42.1 Fracture of scapula	0.638	0.362
T90 Sequelae of injuries of head	0.638	0.362
M87 Osteonecrosis	0.637	0.363
Z74 Problems related to care-provider dependency	0.636	0.364
M70-M79 Other soft tissue disorders	0.636	0.364
E61 Deficiency of other nutrient elements	0.635	0.365
E29 Testicular dysfunction	0.635	0.365
T20.7 Corrosion of third degree of head and neck	0.634	0.365
T20.6 Corrosion of second degree of head and neck	0.634	0.365
T20.5 Corrosion of first degree of head and neck	0.634	0.365
T20.4 Corrosion of unspecified degree of head and neck	0.634	0.365
T20.3 Burn of third degree of head and neck	0.634	0.365
T92.1 Sequelae of fracture of arm	0.634	0.366
G03 Meningitis due to other and unspecified causes	0.634	0.366
E21.3 Hyperparathyroidism, unspecified	0.633	0.367
I77.0 Arteriovenous fistula, acquired	0.633	0.367
M32 Systemic lupus erythematosus	0.632	0.368
Z75.3 Unavailability and inaccessibility of health-care facilities	0.632	0.368
D86 Sarcoidosis	0.632	0.368
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.631	0.368
I77.9 Disorder of arteries and arterioles, unspecified	0.631	0.369
S14 Injury of nerves and spinal cord at neck level	0.629	0.371
Chapter VIII Diseases of the ear and mastoid process	0.628	0.372
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.627	0.373
S43.6 Sprain and strain of sternoclavicular joint	0.627	0.373
S43.5 Sprain and strain of acromioclavicular joint	0.627	0.373
S43.4 Sprain and strain of shoulder joint	0.627	0.373
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.627	0.373
S43.2 Dislocation of sternoclavicular joint	0.627	0.373
S70 Superficial injury of hip and thigh	0.627	0.373
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.627	0.373
Z73 Problems related to life-management difficulty	0.624	0.375
T94 Sequelae of injuries involving multiple and unspecified body regions	0.623	0.377
T50.8 Diagnostic agents	0.623	0.377
T50.7 Analeptics and opioid receptor antagonists	0.623	0.377
T50.6 Antidotes and chelating agents, not elsewhere classified	0.623	0.377
T50.5 Appetite depressants	0.623	0.377
T50.4 Drugs affecting uric acid metabolism	0.623	0.377
T50.3 Electrolytic, caloric and water-balance agents	0.623	0.377
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.623	0.377
T50.1 Loop [high-ceiling] diuretics	0.623	0.377
T50.0 Mineralocorticoids and their antagonists	0.623	0.377
M62 Other disorders of muscle	0.623	0.377
T79-T79 Certain early complications of trauma	0.623	0.377
T98 Sequelae of other and unspecified effects of external causes	0.622	0.378
G45.9 Transient cerebral ischaemic attack, unspecified	0.621	0.379
E40-E46 Malnutrition	0.621	0.379
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.620	0.379
G40.4 Other generalised epilepsy and epileptic syndromes	0.620	0.380
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.620	0.380
M30 Polyarteritis nodosa and related conditions	0.620	0.380
D63.1 Anaemia in other chronic diseases classified elsewhere	0.619	0.380
G90-G99 Other disorders of the nervous system	0.619	0.381
I09 Other rheumatic heart diseases	0.618	0.382
I06 Rheumatic aortic valve diseases	0.618	0.382
S41.0 Open wound of shoulder	0.618	0.382
S11 Open wound of neck	0.618	0.382
S80-S89 Injuries to the knee and lower leg	0.615	0.385
M40-M43 Deforming dorsopathies	0.615	0.385
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.614	0.386
F80 Specific developmental disorders of speech and language	0.613	0.387
Z00-Z13 Persons encountering health services for examination and investigation	0.612	0.388
S90-S99 Injuries to the ankle and foot	0.611	0.389
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.611	0.389
M24.8 Other specific joint derangements, not elsewhere classified	0.611	0.389
I74.8 Embolism and thrombosis of other arteries	0.611	0.389
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.611	0.389
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.611	0.389
I74.0 Embolism and thrombosis of abdominal aorta	0.611	0.389
D67 Hereditary factor IX deficiency	0.609	0.390
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.609	0.390
L10-L14 Bullous disorders	0.609	0.391
G23 Other degenerative diseases of basal ganglia	0.608	0.392
G21 Secondary Parkinsonism	0.608	0.392
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.608	0.392
G22 Parkinsonism in diseases classified elsewhere	0.608	0.392
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.608	0.392
T18.8 Foreign body in other and multiple parts of alimentary tract	0.608	0.392
T18.5 Foreign body in anus and rectum	0.608	0.392
T18.4 Foreign body in colon	0.608	0.392
T18.3 Foreign body in small intestine	0.608	0.392
T18.2 Foreign body in stomach	0.608	0.392
T18.0 Foreign body in mouth	0.608	0.392
S42.3 Fracture of shaft of humerus	0.608	0.392
T51 Toxic effect of alcohol	0.608	0.392
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.608	0.392
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.608	0.392
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.605	0.394
I67.7 Cerebral arteritis, not elsewhere classified	0.605	0.395
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.605	0.395
I67.5 Moyamoya disease	0.605	0.395
I67.4 Hypertensive encephalopathy	0.605	0.395
I67.3 Progressive vascular leukoencephalopathy	0.605	0.395
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.604	0.396
M48 Other spondylopathies	0.604	0.396
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.604	0.396
I61.4 Intracerebral haemorrhage in cerebellum	0.603	0.396
Z01.8 Other specified special examinations	0.603	0.397
T36.0 Penicillins	0.603	0.397
M25.59 Pain in joint (Site unspecified)	0.603	0.397
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.603	0.397
M25.58 Pain in joint (Other)	0.602	0.398
E35 Disorders of endocrine glands in diseases classified elsewhere	0.602	0.398
E32 Diseases of thymus	0.602	0.398
E31 Polyglandular dysfunction	0.602	0.398
E30 Disorders of puberty, not elsewhere classified	0.602	0.398
E25 Adrenogenital disorders	0.602	0.398
D50.1 Sideropenic dysphagia	0.601	0.398
D51 Vitamin B12 deficiency anaemia	0.602	0.398
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.600	0.400
S42.21 Fracture of upper end of humerus (open)	0.599	0.400
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.599	0.401
Q35-Q37 Cleft lip and cleft palate	0.599	0.401
Q30-Q34 Congenital malformations of the respiratory system	0.599	0.401
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.599	0.401
F34 Persistent mood [affective] disorders	0.598	0.402
I99 Other and unspecified disorders of circulatory system	0.598	0.402
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.597	0.403
I74.5 Embolism and thrombosis of iliac artery	0.596	0.404
G25.9 Extrapyramidal and movement disorder, unspecified	0.596	0.404
G25.6 Drug-induced tics and other tics of organic origin	0.596	0.404
G25.5 Other chorea	0.596	0.404
G25.4 Drug-induced chorea	0.596	0.404
G25.2 Other specified forms of tremor	0.596	0.404
G25.1 Drug-induced tremor	0.596	0.404
G30 Alzheimer's disease	0.596	0.404
D50.8 Other iron deficiency anaemias	0.595	0.405
S43.1 Dislocation of acromioclavicular joint	0.594	0.406
E70-E90 Metabolic disorders	0.593	0.407
S17 Crushing injury of neck	0.592	0.408
S15 Injury of blood vessels at neck level	0.592	0.408
S18 Traumatic amputation at neck level	0.592	0.408
S16 Injury of muscle and tendon at neck level	0.592	0.408
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.591	0.409
D64.8 Other specified anaemias	0.590	0.409
D64.4 Congenital dyserythropoietic anaemia	0.590	0.409
D64.3 Other sideroblastic anaemias	0.590	0.409
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.590	0.409
D64.1 Secondary sideroblastic anaemia due to disease	0.590	0.409
D64.0 Hereditary sideroblastic anaemia	0.590	0.409
I95 Hypotension	0.590	0.410
E28 Ovarian dysfunction	0.590	0.410
F30 Manic episode	0.590	0.410
F33 Recurrent depressive disorder	0.590	0.410
M25.37 Other instability of joint (Ankle and foot)	0.589	0.411
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.589	0.411
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.589	0.411
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.589	0.411
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.589	0.411
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.589	0.411
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.589	0.411
F39 Unspecified mood [affective] disorder	0.588	0.411
E34 Other endocrine disorders	0.588	0.412
G06 Intracranial and intraspinal abscess and granuloma	0.588	0.412
I11.9 Hypertensive heart disease without (congestive) heart failure	0.588	0.412
F40-F48 Neurotic, stress-related and somatoform disorders	0.587	0.413
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.586	0.414
D70-D77 Other diseases of blood and blood-forming organs	0.586	0.414
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.586	0.414
F29 Unspecified nonorganic psychosis	0.586	0.414
E20 Hypoparathyroidism	0.585	0.415
M77 Other enthesopathies	0.585	0.415
T45.5 Anticoagulants	0.583	0.417
Z74.0 Reduced mobility	0.583	0.417
D68.4 Acquired coagulation factor deficiency	0.583	0.417
D68.1 Hereditary factor XI deficiency	0.583	0.417
S52.10 Fracture of upper end of radius (closed)	0.582	0.417
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.582	0.418
D89.3 Immune reconstitution syndrome	0.582	0.418
D89.1 Cryoglobulinaemia	0.582	0.418
D89.0 Polyclonal hypergammaglobulinaemia	0.582	0.418

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations