TreeWAS – Variant ID: rs13103557

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.044	0.956	0.000
M20.5 Other deformities of toe(s) (acquired)	0.034	0.966	0.000
M25 Other joint disorders, not elsewhere classified	0.022	0.978	0.000
M25.4 Effusion of joint	0.022	0.978	0.000
M25.7 Osteophyte	0.022	0.978	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.021	0.979	0.000
M20 Acquired deformities of fingers and toes	0.020	0.980	0.000
M25.46 Effusion of joint (Lower leg)	0.019	0.981	0.000
M20-M25 Other joint disorders	0.019	0.981	0.000
M25.8 Other specified joint disorders	0.018	0.982	0.000
M25.47 Effusion of joint (Ankle and foot)	0.018	0.982	0.000
M25.9 Joint disorder, unspecified	0.018	0.982	0.000
M25.72 Osteophyte (Upper arm)	0.018	0.982	0.000
M25.44 Effusion of joint (Hand)	0.018	0.982	0.000
M24 Other specific joint derangements	0.018	0.982	0.000
M25.42 Effusion of joint (Upper arm)	0.018	0.982	0.000
M25.71 Osteophyte (Shoulder region)	0.018	0.982	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.017	0.983	0.000
M25.3 Other instability of joint	0.017	0.983	0.000
M25.0 Haemarthrosis	0.017	0.983	0.000
M25.74 Osteophyte (Hand)	0.017	0.983	0.000
M25.77 Osteophyte (Ankle and foot)	0.017	0.983	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.017	0.983	0.000
M20.3 Other deformity of hallux (acquired)	0.016	0.984	0.000
M25.86 Other specified joint disorders (Lower leg)	0.016	0.984	0.000
M25.2 Flail joint	0.016	0.984	0.000
M25.1 Fistula of joint	0.016	0.984	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.016	0.984	0.000
M25.49 Effusion of joint (Site unspecified)	0.016	0.984	0.000
M25.48 Effusion of joint (Other)	0.016	0.984	0.000
M25.43 Effusion of joint (Forearm)	0.016	0.984	0.000
M25.41 Effusion of joint (Shoulder region)	0.016	0.984	0.000
M25.40 Effusion of joint (Multiple sites)	0.016	0.984	0.000
M35 Other systemic involvement of connective tissue	0.016	0.984	0.000
M25.79 Osteophyte (Site unspecified)	0.016	0.984	0.000
M25.73 Osteophyte (Forearm)	0.016	0.984	0.000
M25.70 Osteophyte (Multiple sites)	0.016	0.984	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.015	0.984	0.000
M20.0 Deformity of finger(s)	0.015	0.984	0.000
M22 Disorders of patella	0.015	0.985	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.015	0.985	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.015	0.985	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.014	0.985	0.000
M24.0 Loose body in joint	0.014	0.985	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.014	0.986	0.000
M35.7 Hypermobility syndrome	0.014	0.986	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.014	0.986	0.000
M33 Dermatopolymyositis	0.014	0.986	0.000
M32 Systemic lupus erythematosus	0.014	0.986	0.000
M30 Polyarteritis nodosa and related conditions	0.014	0.986	0.000
M35.0 Sicca syndrome [Sjogren]	0.014	0.986	0.000
M24.1 Other articular cartilage disorders	0.014	0.986	0.000
M24.2 Disorder of ligament	0.014	0.986	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.013	0.986	0.000
M22.2 Patellofemoral disorders	0.013	0.986	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.013	0.986	0.000
M25.88 Other specified joint disorders (Other)	0.013	0.986	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.013	0.986	0.000
M25.83 Other specified joint disorders (Forearm)	0.013	0.986	0.000
M25.82 Other specified joint disorders (Upper arm)	0.013	0.986	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.013	0.986	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.013	0.987	0.000
M25.98 Joint disorder, unspecified (Other)	0.013	0.987	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.013	0.987	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.013	0.987	0.000
M25.94 Joint disorder, unspecified (Hand)	0.013	0.987	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.013	0.987	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.013	0.987	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.013	0.987	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.013	0.987	0.000
M25.31 Other instability of joint (Shoulder region)	0.013	0.987	0.000
M25.06 Haemarthrosis (Lower leg)	0.013	0.987	0.000
M24.9 Joint derangement, unspecified	0.013	0.987	0.000
M24.7 Protrusio acetabuli	0.013	0.987	0.000
M24.6 Ankylosis of joint	0.013	0.987	0.000
M24.5 Contracture of joint	0.013	0.987	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.013	0.987	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.013	0.987	0.000
M22.8 Other disorders of patella	0.013	0.987	0.000
M20.2 Hallux rigidus	0.013	0.987	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.013	0.987	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.012	0.987	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.012	0.987	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.012	0.987	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.012	0.987	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.012	0.987	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.012	0.987	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.012	0.987	0.000
M25.39 Other instability of joint (Site unspecified)	0.012	0.987	0.000
M25.38 Other instability of joint (Other)	0.012	0.987	0.000
M25.37 Other instability of joint (Ankle and foot)	0.012	0.987	0.000
M25.36 Other instability of joint (Lower leg)	0.012	0.987	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.012	0.987	0.000
M25.34 Other instability of joint (Hand)	0.012	0.987	0.000
M25.33 Other instability of joint (Forearm)	0.012	0.987	0.000
M25.32 Other instability of joint (Upper arm)	0.012	0.987	0.000
M25.30 Other instability of joint (Multiple sites)	0.012	0.987	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.012	0.987	0.000
M25.09 Haemarthrosis (Site unspecified)	0.012	0.988	0.000
M25.08 Haemarthrosis (Other)	0.012	0.988	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.012	0.988	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.012	0.988	0.000
M25.04 Haemarthrosis (Hand)	0.012	0.988	0.000
M25.03 Haemarthrosis (Forearm)	0.012	0.988	0.000
M25.02 Haemarthrosis (Upper arm)	0.012	0.988	0.000
M25.01 Haemarthrosis (Shoulder region)	0.012	0.988	0.000
M25.00 Haemarthrosis (Multiple sites)	0.012	0.988	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.012	0.988	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.012	0.988	0.000
E05.8 Other thyrotoxicosis	0.012	0.988	0.000
E05.5 Thyroid crisis or storm	0.012	0.988	0.000
E05.4 Thyrotoxicosis factitia	0.012	0.988	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.012	0.988	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.012	0.988	0.000
M25.84 Other specified joint disorders (Hand)	0.012	0.988	0.000
M35.1 Other overlap syndromes	0.012	0.988	0.000
M25.19 Fistula of joint (Site unspecified)	0.012	0.988	0.000
M25.18 Fistula of joint (Other)	0.012	0.988	0.000
M25.17 Fistula of joint (Ankle and foot)	0.012	0.988	0.000
M25.16 Fistula of joint (Lower leg)	0.012	0.988	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.012	0.988	0.000
M25.14 Fistula of joint (Hand)	0.012	0.988	0.000
M25.13 Fistula of joint (Forearm)	0.012	0.988	0.000
M25.12 Fistula of joint (Upper arm)	0.012	0.988	0.000
M25.11 Fistula of joint (Shoulder region)	0.012	0.988	0.000
M25.10 Fistula of joint (Multiple sites)	0.012	0.988	0.000
M25.29 Flail joint (Site unspecified)	0.012	0.988	0.000
M25.28 Flail joint (Other)	0.012	0.988	0.000
M25.27 Flail joint (Ankle and foot)	0.012	0.988	0.000
M25.26 Flail joint (Lower leg)	0.012	0.988	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.012	0.988	0.000
M25.24 Flail joint (Hand)	0.012	0.988	0.000
M25.23 Flail joint (Forearm)	0.012	0.988	0.000
M25.22 Flail joint (Upper arm)	0.012	0.988	0.000
M25.21 Flail joint (Shoulder region)	0.012	0.988	0.000
M25.20 Flail joint (Multiple sites)	0.012	0.988	0.000
M24.02 Loose body in joint (Upper arm)	0.012	0.988	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.012	0.988	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.012	0.988	0.000
M35.8 Other specified systemic involvement of connective tissue	0.012	0.988	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.012	0.988	0.000
M35.5 Multifocal fibrosclerosis	0.012	0.988	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.012	0.988	0.000
M35.2 Behcet's disease	0.012	0.988	0.000
M25.78 Osteophyte (Other)	0.012	0.988	0.000
M34 Systemic sclerosis	0.011	0.988	0.000
M24.01 Loose body in joint (Shoulder region)	0.011	0.989	0.000
M22.1 Recurrent subluxation of patella	0.011	0.989	0.000
M22.9 Disorder of patella, unspecified	0.011	0.989	0.000
M22.0 Recurrent dislocation of patella	0.011	0.989	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.011	0.989	0.000
M21 Other acquired deformities of limbs	0.011	0.989	0.000
K22.1 Ulcer of oesophagus	0.000	0.989	0.011
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.011	0.989	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.011	0.989	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.011	0.989	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.011	0.989	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.011	0.989	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.011	0.989	0.000
M24.26 Disorder of ligament (Lower leg)	0.011	0.989	0.000
M22.3 Other derangements of patella	0.011	0.989	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.011	0.989	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.011	0.989	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.011	0.989	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.011	0.989	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.011	0.989	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.011	0.989	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.011	0.989	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.011	0.989	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.011	0.989	0.000
M24.09 Loose body in joint (Site unspecified)	0.010	0.989	0.000
M24.08 Loose body in joint (Other)	0.010	0.989	0.000
M24.06 Loose body in joint-Lower leg	0.010	0.989	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.010	0.989	0.000
M24.04 Loose body in joint (Hand)	0.010	0.989	0.000
M24.03 Loose body in joint (Forearm)	0.010	0.989	0.000
M24.00 Loose body in joint (Multiple sites)	0.010	0.989	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.010	0.989	0.000
M31 Other necrotising vasculopathies	0.010	0.989	0.000
M24.07 Loose body in joint (Ankle and foot)	0.010	0.990	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.010	0.990	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.010	0.990	0.000
M30.2 Juvenile polyarteritis	0.010	0.990	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.010	0.990	0.000
M30.0 Polyarteritis nodosa	0.010	0.990	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.010	0.990	0.000
M32.8 Other forms of systemic lupus erythematosus	0.010	0.990	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.010	0.990	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.010	0.990	0.000
M33.9 Dermatopolymyositis, unspecified	0.010	0.990	0.000
M33.2 Polymyositis	0.010	0.990	0.000
M33.1 Other dermatomyositis	0.010	0.990	0.000
M33.0 Juvenile dermatomyositis	0.010	0.990	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.010	0.990	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.010	0.990	0.000
M36.3 Arthropathy in other blood disorders	0.010	0.990	0.000
M36.2 Haemophilic arthropathy	0.010	0.990	0.000
M36.1 Arthropathy in neoplastic disease	0.010	0.990	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.010	0.990	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.010	0.990	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.010	0.990	0.000
M24.18 Other articular cartilage disorders (Other)	0.010	0.990	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.010	0.990	0.000
M24.14 Other articular cartilage disorders (Hand)	0.010	0.990	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.010	0.990	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.010	0.990	0.000
M24.29 Disorder of ligament (Site unspecified)	0.010	0.990	0.000
M24.28 Disorder of ligament (Other)	0.010	0.990	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.010	0.990	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.010	0.990	0.000
M24.24 Disorder of ligament (Hand)	0.010	0.990	0.000
M24.22 Disorder of ligament (Upper arm)	0.010	0.990	0.000
M24.21 Disorder of ligament (Shoulder region)	0.010	0.990	0.000
M24.20 Disorder of ligament (Multiple sites)	0.010	0.990	0.000
M24.23 Disorder of ligament (Forearm)	0.010	0.990	0.000
M25.76 Osteophyte (Lower leg)	0.010	0.990	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.009	0.990	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.009	0.990	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.009	0.990	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.009	0.990	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.009	0.990	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.009	0.990	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.009	0.990	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.009	0.990	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.009	0.990	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.009	0.990	0.000
M24.59 Contracture of joint (Site unspecified)	0.009	0.990	0.000
M24.58 Contracture of joint (Other)	0.009	0.990	0.000
M24.57 Contracture of joint (Ankle and foot)	0.009	0.990	0.000
M24.56 Contracture of joint (Lower leg)	0.009	0.990	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.009	0.990	0.000
M24.54 Contracture of joint (Hand)	0.009	0.990	0.000
M24.53 Contracture of joint (Forearm)	0.009	0.990	0.000
M24.52 Contracture of joint (Upper arm)	0.009	0.990	0.000
M24.51 Contracture of joint (Shoulder region)	0.009	0.990	0.000
M24.50 Contracture of joint (Multiple sites)	0.009	0.990	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.009	0.990	0.000
M24.68 Ankylosis of joint (Other)	0.009	0.990	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.009	0.990	0.000
M24.66 Ankylosis of joint (Lower leg)	0.009	0.990	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.009	0.990	0.000
M24.64 Ankylosis of joint (Hand)	0.009	0.990	0.000
M24.63 Ankylosis of joint (Forearm)	0.009	0.990	0.000
M24.62 Ankylosis of joint (Upper arm)	0.009	0.990	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.009	0.990	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.009	0.990	0.000
M24.79 Protrusio acetabuli-Site unspec	0.009	0.990	0.000
M24.78 Protrusio acetabuli-Other	0.009	0.990	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.009	0.990	0.000
M24.76 Protrusio acetabuli-Lower leg	0.009	0.990	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.009	0.990	0.000
M24.74 Protrusio acetabuli-Hand	0.009	0.990	0.000
M24.73 Protrusio acetabuli-Forearm	0.009	0.990	0.000
M24.72 Protrusio acetabuli-Upper arm	0.009	0.990	0.000
M24.71 Protrusio acetabuli-Shldr region	0.009	0.990	0.000
M24.70 Protrusio acetabuli-Mult sites	0.009	0.990	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.009	0.990	0.000
M24.98 Joint derangement, unspecified (Other)	0.009	0.990	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.009	0.990	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.009	0.990	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.009	0.990	0.000
M24.94 Joint derangement, unspecified (Hand)	0.009	0.990	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.009	0.990	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.009	0.990	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.009	0.990	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.009	0.990	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.009	0.990	0.000
M20.4 Other hammer toe(s) (acquired)	0.009	0.991	0.000
M34.1 CR(E)ST syndrome	0.009	0.991	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.009	0.991	0.000
M21.6 Other acquired deformities of ankle and foot	0.009	0.991	0.000
M21.2 Flexion deformity	0.009	0.991	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.008	0.991	0.000
M34.8 Other forms of systemic sclerosis	0.008	0.991	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.008	0.991	0.000
M34.0 Progressive systemic sclerosis	0.008	0.991	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.008	0.991	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.008	0.992	0.000
M21.4 Flat foot [pes planus] (acquired)	0.008	0.992	0.000
M21.9 Acquired deformity of limb, unspecified	0.008	0.992	0.000
M21.8 Other specified acquired deformities of limbs	0.008	0.992	0.000
M21.7 Unequal limb length (acquired)	0.008	0.992	0.000
M31.9 Necrotising vasculopathy, unspecified	0.008	0.992	0.000
M31.8 Other specified necrotising vasculopathies	0.008	0.992	0.000
M31.7 Microscopic polyangiitis	0.008	0.992	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.008	0.992	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.008	0.992	0.000
M31.2 Lethal midline granuloma	0.008	0.992	0.000
M31.1 Thrombotic microangiopathy	0.008	0.992	0.000
M31.0 Hypersensitivity angiitis	0.008	0.992	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.007	0.992	0.000
M21.1 Varus deformity, not elsewhere classified	0.007	0.993	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.007	0.993	0.000
M21.24 Flexion deformity (Hand)	0.007	0.993	0.000
M35.3 Polymyalgia rheumatica	0.007	0.993	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.007	0.993	0.000
M22.4 Chondromalacia patellae	0.006	0.993	0.000
M21.27 Flexion deformity (Ankle and foot)	0.006	0.993	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.006	0.993	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.006	0.993	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.006	0.993	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.006	0.993	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.006	0.993	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.006	0.993	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.006	0.993	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.006	0.993	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.006	0.993	0.000
M21.29 Flexion deformity (Site unspecified)	0.006	0.993	0.000
M21.28 Flexion deformity (Other)	0.006	0.993	0.000
M21.26 Flexion deformity (Lower leg)	0.006	0.993	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.006	0.993	0.000
M21.23 Flexion deformity (Forearm)	0.006	0.993	0.000
M21.22 Flexion deformity (Upper arm)	0.006	0.993	0.000
M21.21 Flexion deformity (Shoulder region)	0.006	0.993	0.000
M21.20 Flexion deformity (Multiple sites)	0.006	0.993	0.000
M31.6 Other giant cell arteritis	0.006	0.993	0.000
M21.3 Wrist or foot drop (acquired)	0.006	0.993	0.001
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.006	0.994	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.006	0.994	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.006	0.994	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.006	0.994	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.006	0.994	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.006	0.994	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.006	0.994	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.006	0.994	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.006	0.994	0.000
M31.3 Wegener's granulomatosis	0.006	0.994	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.006	0.994	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.006	0.994	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.006	0.994	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.006	0.994	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.006	0.994	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.006	0.994	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.006	0.994	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.006	0.994	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.006	0.994	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.006	0.994	0.000
E10.9 Without complications	0.000	0.994	0.006
M21.79 Unequal limb length (acquired) (Site unspecified)	0.006	0.994	0.000
M21.78 Unequal limb length (acquired)-Other	0.006	0.994	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.006	0.994	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.006	0.994	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.006	0.994	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.006	0.994	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.006	0.994	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.006	0.994	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.006	0.994	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.006	0.994	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.006	0.994	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.006	0.994	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.006	0.994	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.006	0.994	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.006	0.994	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.006	0.994	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.006	0.994	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.006	0.994	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.006	0.994	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.006	0.994	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.006	0.994	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.006	0.994	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.006	0.994	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.006	0.994	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.006	0.994	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.006	0.994	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.006	0.994	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.006	0.994	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.006	0.994	0.000
M21.0 Valgus deformity, not elsewhere classified	0.005	0.994	0.001
M34.9 Systemic sclerosis, unspecified	0.005	0.994	0.001
Z98.0 Intestinal bypass and anastomosis status	0.000	0.994	0.006
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.005	0.994	0.000
T78.4 Allergy, unspecified	0.000	0.994	0.006
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.005	0.994	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.005	0.994	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.005	0.994	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.005	0.994	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.005	0.994	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.005	0.994	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.005	0.994	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.005	0.994	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.995	0.005
E10.3 With ophthalmic complications	0.000	0.995	0.005
M21.39 Wrist or foot drop (acquired)-Site unspec	0.004	0.995	0.001
M21.38 Wrist or foot drop (acquired)-Other	0.004	0.995	0.001
M21.36 Wrist or foot drop (acquired)-Lower leg	0.004	0.995	0.001
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.004	0.995	0.001
M21.34 Wrist or foot drop (acquired) (Hand)	0.004	0.995	0.001
M21.33 Wrist or foot drop (acquired) (Forearm)	0.004	0.995	0.001
M21.32 Wrist or foot drop (acquired)-Upper arm	0.004	0.995	0.001
M21.31 Wrist or foot drop (acquired)-Shldr region	0.004	0.995	0.001
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.004	0.995	0.001
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.004	0.995	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.004	0.995	0.001
M21.08 Valgus deformity, not elsewhere classified (Other)	0.004	0.995	0.001
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.004	0.995	0.001
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.004	0.995	0.001
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.004	0.995	0.001
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.004	0.995	0.001
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.004	0.995	0.001
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.004	0.995	0.001
E10.5 With peripheral circulatory complications	0.000	0.995	0.004
M40-M43 Deforming dorsopathies	0.004	0.995	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.996	0.004
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
M43 Other deforming dorsopathies	0.004	0.996	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.996	0.004
M43.16 Spondylolisthesis (Lumbar region)	0.004	0.996	0.000
M41 Scoliosis	0.004	0.996	0.000
E10.8 With unspecified complications	0.000	0.996	0.004
E10.7 With multiple complications	0.000	0.996	0.004
E10.6 With other specified complications	0.000	0.996	0.004
E10.4 With neurological complications	0.000	0.996	0.004
E10.2 With renal complications	0.000	0.996	0.004
E10.0 With coma	0.000	0.996	0.004
E10.1 With ketoacidosis	0.000	0.996	0.004
M91-M94 Chondropathies	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
M43.1 Spondylolisthesis	0.004	0.996	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.996	0.001
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
T78.3 Angioneurotic oedema	0.000	0.996	0.004
M40 Kyphosis and lordosis	0.004	0.996	0.000
Z43.3 Attention to colostomy	0.000	0.996	0.004
M94 Other disorders of cartilage	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
M86-M90 Other osteopathies	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.996	0.001
M94.8 Other specified disorders of cartilage	0.004	0.996	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.004	0.996	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
M60-M63 Disorders of muscles	0.004	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.004	0.996	0.000
M42 Spinal osteochondrosis	0.003	0.996	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
T78.8 Other adverse effects, not elsewhere classified	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.003	0.997	0.000
M00-M03 Infectious arthropathies	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.997	0.001
M94.88 Other specified disorders of cartilage (Other)	0.003	0.997	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.997	0.003
M89 Other disorders of bone	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
M65-M68 Disorders of synovium and tendon	0.003	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
M40.2 Other and unspecified kyphosis	0.003	0.997	0.000
M43.9 Deforming dorsopathy, unspecified	0.003	0.997	0.000
M43.8 Other specified deforming dorsopathies	0.003	0.997	0.000
M43.6 Torticollis	0.003	0.997	0.000
M43.5 Other recurrent vertebral subluxation	0.003	0.997	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.003	0.997	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.003	0.997	0.000
M43.2 Other fusion of spine	0.003	0.997	0.000
M43.0 Spondylolysis	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.003	0.997	0.000
M93 Other osteochondropathies	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.003	0.997	0.000
C20 Malignant neoplasm of rectum	0.000	0.997	0.003
M41.8 Other forms of scoliosis	0.003	0.997	0.000
M41.5 Other secondary scoliosis	0.003	0.997	0.000
M41.4 Neuromuscular scoliosis	0.003	0.997	0.000
M41.3 Thoracogenic scoliosis	0.003	0.997	0.000
M41.2 Other idiopathic scoliosis	0.003	0.997	0.000
M41.1 Juvenile idiopathic scoliosis	0.003	0.997	0.000
M41.0 Infantile idiopathic scoliosis	0.003	0.997	0.000
M05-M14 Inflammatory polyarthropathies	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
M92 Other juvenile osteochondrosis	0.003	0.997	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.003	0.997	0.000
D23.4 Skin of scalp and neck	0.003	0.997	0.000
M86 Osteomyelitis	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.003	0.997	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.003	0.997	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.003	0.997	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.003	0.997	0.000
M43.12 Spondylolisthesis (Cervical region)	0.003	0.997	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations