TreeWAS – Variant ID: rs13144478

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I70-I79 Diseases of arteries, arterioles and capillaries	0.159	0.841	0.000
I71 Aortic aneurysm and dissection	0.153	0.847	0.000
I77 Other disorders of arteries and arterioles	0.152	0.848	0.000
I74 Arterial embolism and thrombosis	0.149	0.851	0.000
I78 Diseases of capillaries	0.143	0.857	0.000
I77.1 Stricture of artery	0.143	0.857	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.141	0.859	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.140	0.860	0.000
I73 Other peripheral vascular diseases	0.139	0.861	0.000
I73.9 Peripheral vascular disease, unspecified	0.133	0.867	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.132	0.868	0.000
I78.1 Naevus, nonneoplastic	0.129	0.871	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.126	0.874	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.125	0.875	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.125	0.875	0.000
I70 Atherosclerosis	0.125	0.875	0.000
I74.5 Embolism and thrombosis of iliac artery	0.120	0.880	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.118	0.882	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.118	0.882	0.000
I71.0 Dissection of aorta [any part]	0.113	0.887	0.000
I78.8 Other diseases of capillaries	0.111	0.889	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.110	0.890	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.110	0.890	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.110	0.890	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.110	0.890	0.000
I77.5 Necrosis of artery	0.109	0.891	0.000
I77.4 Coeliac artery compression syndrome	0.109	0.891	0.000
I77.3 Arterial fibromuscular dysplasia	0.109	0.891	0.000
I77.2 Rupture of artery	0.109	0.891	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.108	0.892	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.107	0.893	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.107	0.893	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.107	0.893	0.000
I77.0 Arteriovenous fistula, acquired	0.105	0.895	0.000
I72 Other aneurysm	0.104	0.895	0.000
I74.8 Embolism and thrombosis of other arteries	0.104	0.896	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.104	0.896	0.000
I78.9 Disease of capillaries, unspecified	0.103	0.897	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.101	0.899	0.000
I77.8 Other specified disorders of arteries and arterioles	0.100	0.900	0.000
I73.8 Other specified peripheral vascular diseases	0.100	0.900	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.100	0.900	0.000
I70.0 Atherosclerosis of aorta	0.095	0.905	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.095	0.905	0.000
I70.1 Atherosclerosis of renal artery	0.091	0.908	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.090	0.910	0.000
I79.1 Aortitis in diseases classified elsewhere	0.090	0.910	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.090	0.910	0.000
I70.9 Generalised and unspecified atherosclerosis	0.090	0.910	0.000
I70.8 Atherosclerosis of other arteries	0.090	0.910	0.000
I77.6 Arteritis, unspecified	0.088	0.912	0.000
I72.2 Aneurysm of renal artery	0.083	0.917	0.000
I72.4 Aneurysm of artery of lower extremity	0.077	0.922	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.076	0.924	0.000
I72.9 Aneurysm of unspecified site	0.075	0.925	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.075	0.925	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.075	0.925	0.000
I72.1 Aneurysm of artery of upper extremity	0.075	0.925	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.073	0.927	0.000
I72.0 Aneurysm of carotid artery	0.071	0.929	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.068	0.932	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.067	0.932	0.000
I72.3 Aneurysm of iliac artery	0.067	0.933	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.066	0.934	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.064	0.935	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.064	0.935	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.064	0.935	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.064	0.935	0.000
I72.8 Aneurysm of other specified arteries	0.064	0.936	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.064	0.936	0.000
I73.0 Raynaud's syndrome	0.052	0.948	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.010	0.990	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.992	0.008
T39.1 4-Aminophenol derivatives	0.000	0.992	0.008
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.993	0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.993	0.007
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.993	0.007
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.994	0.006
T40.4 Other synthetic narcotics	0.000	0.994	0.006
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.994	0.006
T50.8 Diagnostic agents	0.000	0.994	0.005
T50.7 Analeptics and opioid receptor antagonists	0.000	0.994	0.005
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.994	0.005
T50.5 Appetite depressants	0.000	0.994	0.005
T50.4 Drugs affecting uric acid metabolism	0.000	0.994	0.005
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.994	0.005
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.994	0.005
T50.1 Loop [high-ceiling] diuretics	0.000	0.994	0.005
T50.0 Mineralocorticoids and their antagonists	0.000	0.994	0.005
T40.2 Other opioids	0.000	0.994	0.006
T40.6 Other and unspecified narcotics	0.000	0.995	0.005
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.995	0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.995	0.005
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.995	0.005
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.995	0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.995	0.005
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.995	0.005
T39.4 Antirheumatics, not elsewhere classified	0.000	0.995	0.005
T39.2 Pyrazolone derivatives	0.000	0.995	0.005
T42.4 Benzodiazepines	0.000	0.995	0.005
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.995	0.005
T39.0 Salicylates	0.000	0.995	0.005
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.995	0.005
T40.8 Lysergide [LSD]	0.000	0.995	0.005
T40.7 Cannabis (derivatives)	0.000	0.995	0.005
T40.5 Cocaine	0.000	0.995	0.005
T40.3 Methadone	0.000	0.995	0.005
T40.1 Heroin	0.000	0.995	0.005
T40.0 Opium	0.000	0.995	0.005
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.995	0.005
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
T45.0 Antiallergic and antiemetic drugs	0.000	0.995	0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.995	0.005
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.995	0.005
T36 Poisoning by systemic antibiotics	0.000	0.995	0.005
I08.1 Disorders of both mitral and tricuspid valves	0.005	0.995	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
T45.5 Anticoagulants	0.000	0.995	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
T42.1 Iminostilbenes	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.996	0.004
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.996	0.004
T45.8 Other primarily systemic and haematological agents	0.000	0.996	0.004
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.996	0.004
T45.6 Fibrinolysis-affecting drugs	0.000	0.996	0.004
T45.4 Iron and its compounds	0.000	0.996	0.004
T45.3 Enzymes, not elsewhere classified	0.000	0.996	0.004
T45.2 Vitamins, not elsewhere classified	0.000	0.996	0.004
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.996	0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.996	0.004
T46.7 Peripheral vasodilators	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.996	0.004
T46.1 Calcium-channel blockers	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.996	0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T41.5 Therapeutic gases	0.000	0.996	0.004
T41.4 Anaesthetic, unspecified	0.000	0.996	0.004
T41.3 Local anaesthetics	0.000	0.996	0.004
T41.2 Other and unspecified general anaesthetics	0.000	0.996	0.004
T41.1 Intravenous anaesthetics	0.000	0.996	0.004
T41.0 Inhaled anaesthetics	0.000	0.996	0.004
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.996	0.004
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.996	0.004
T48.5 Anti-common-cold drugs	0.000	0.996	0.004
T48.4 Expectorants	0.000	0.996	0.004
T48.3 Antitussives	0.000	0.996	0.004
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.996	0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.996	0.004
T48.0 Oxytocic drugs	0.000	0.996	0.004
T49.9 Topical agent, unspecified	0.000	0.996	0.004
T49.8 Other topical agents	0.000	0.996	0.004
T49.7 Dental drugs, topically applied	0.000	0.996	0.004
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.004
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.004
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.004
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.004
T49.2 Local astringents and local detergents	0.000	0.996	0.004
T49.1 Antipruritics	0.000	0.996	0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.996	0.004
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.996	0.004
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.004
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.004
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.004
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.996	0.004
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.996	0.004
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.996	0.004
T44.0 Anticholinesterase agents	0.000	0.996	0.004
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
I22 Subsequent myocardial infarction	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T38.1 Thyroid hormones and substitutes	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.004
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.004
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.004
T47.7 Emetics	0.000	0.996	0.004
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
T47.5 Digestants	0.000	0.996	0.004
T47.4 Other laxatives	0.000	0.996	0.004
T47.3 Saline and osmotic laxatives	0.000	0.996	0.004
T47.2 Stimulant laxatives	0.000	0.996	0.004
T47.0 Histamine H(2)-receptor antagonists	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.000	0.996	0.003
T36.8 Other systemic antibiotics	0.000	0.996	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.996	0.003
T36.6 Rifamycins	0.000	0.996	0.003
T36.5 Aminoglycosides	0.000	0.996	0.003
T36.4 Tetracyclines	0.000	0.996	0.003
T36.3 Macrolides	0.000	0.996	0.003
T36.2 Chloramphenicol group	0.000	0.996	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.996	0.003
H65 Nonsuppurative otitis media	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
I08 Multiple valve diseases	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
I95.9 Hypotension, unspecified	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.003	0.997	0.000
I22.8 Subsequent myocardial infarction of other sites	0.003	0.997	0.000
Chapter IX Diseases of the circulatory system	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
I27 Other pulmonary heart diseases	0.003	0.997	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.003	0.997	0.000
H52.0 Hypermetropia	0.000	0.997	0.003
O36.6 Maternal care for excessive foetal growth	0.003	0.997	0.000
O36.4 Maternal care for intra-uterine death	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
I27.8 Other specified pulmonary heart diseases	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
I08.9 Multiple valve disease, unspecified	0.002	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.002	0.997	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
I28 Other diseases of pulmonary vessels	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.002	0.998	0.000
M54.59 Low back pain (Site unspecified)	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.002	0.998	0.000
I00-I02 Acute rheumatic fever	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
O45.9 Premature separation of placenta, unspecified	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
O41.0 Oligohydramnios	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
O43 Placental disorders	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
G81.9 Hemiplegia, unspecified	0.000	0.998	0.002
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
K31.7 Polyp of stomach and duodenum	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
M54.5 Low back pain	0.000	0.998	0.002
O43.9 Placental disorder, unspecified	0.002	0.998	0.000
O30 Multiple gestation	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
I02 Rheumatic chorea	0.002	0.998	0.000
I01 Rheumatic fever with heart involvement	0.002	0.998	0.000
I00 Rheumatic fever without mention of heart involvement	0.002	0.998	0.000
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
I20.0 Unstable angina	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
I95 Hypotension	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
O31 Complications specific to multiple gestation	0.002	0.998	0.000
O45.8 Other premature separation of placenta	0.002	0.998	0.000
O45.0 Premature separation of placenta with coagulation defect	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
M54.50 Low back pain (Multiple sites in spine)	0.000	0.998	0.002
C54.1 Endometrium	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
I95.0 Idiopathic hypotension	0.002	0.998	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.002	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.002	0.998	0.000
I20-I25 Ischaemic heart diseases	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D36.7 Other specified sites	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.002	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
M54.55 Low back pain (Thoracolumbar region)	0.000	0.998	0.002
M54.54 Low back pain-Thoracic	0.000	0.998	0.002
M54.53 Low back pain-Cervicothoracic	0.000	0.998	0.002
M54.52 Low back pain-Cervical	0.000	0.998	0.002
M54.51 Low back pain-Occipit-atl-axl	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
O30.9 Multiple gestation, unspecified	0.002	0.998	0.000
O30.8 Other multiple gestation	0.002	0.998	0.000
O30.2 Quadruplet pregnancy	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.002	0.998	0.000
O32.4 Maternal care for high head at term	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.001	0.998	0.000
I01.8 Other acute rheumatic heart disease	0.001	0.998	0.000
I01.2 Acute rheumatic myocarditis	0.001	0.998	0.000
I01.1 Acute rheumatic endocarditis	0.001	0.998	0.000
I01.0 Acute rheumatic pericarditis	0.001	0.998	0.000
I02.9 Rheumatic chorea without heart involvement	0.001	0.998	0.000
I02.0 Rheumatic chorea with heart involvement	0.001	0.998	0.000
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.002	0.998	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.001	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.001	0.998	0.000
Q50.2 Congenital torsion of ovary	0.001	0.998	0.000
Q50.1 Developmental ovarian cyst	0.001	0.998	0.000
Q50.0 Congenital absence of ovary	0.001	0.998	0.000
H70 Mastoiditis and related conditions	0.001	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
B44.9 Aspergillosis, unspecified	0.002	0.998	0.000
O31.8 Other complications specific to multiple gestation	0.001	0.998	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.001	0.998	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.001	0.998	0.000
O31.0 Papyraceous foetus	0.001	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.001	0.998	0.000
O33.8 Maternal care for disproportion of other origin	0.001	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.001	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.001	0.998	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.001	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.001	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.001	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.001	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.001	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.001	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.001	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.001	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.001	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.998	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.998	0.002
C56 Malignant neoplasm of ovary	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.001	0.998	0.000
E83 Disorders of mineral metabolism	0.000	0.998	0.002
O43.8 Other placental disorders	0.001	0.998	0.000
O69.8 Labour and delivery complicated by other cord complications	0.001	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.998	0.000
X41.9 Unspecified place	0.000	0.998	0.001
I23 Certain current complications following acute myocardial infarction	0.001	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.998	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.998	0.000
H68.0 Eustachian salpingitis	0.001	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.001	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
Z51.5 Palliative care	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.998	0.000
O32.8 Maternal care for other malpresentation of foetus	0.001	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.001	0.998	0.000
H66 Suppurative and unspecified otitis media	0.001	0.998	0.000
I20 Angina pectoris	0.002	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.001	0.998	0.000
H74.1 Adhesive middle ear disease	0.001	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.001
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.998	0.000
O32.6 Maternal care for compound presentation	0.001	0.998	0.000
Q21.1 Atrial septal defect	0.001	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations