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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13194087
log Bayes Factor = 7.20708
Chromosome 6   position 31,859,578  (GRCh37) Explore rs13194087 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40 Psoriasis
0.991 0.009 0.000
L40.5 Arthropathic psoriasis
0.983 0.017 0.000
L40.0 Psoriasis vulgaris
0.814 0.186 0.000
L40.8 Other psoriasis
0.794 0.206 0.000
L40.4 Guttate psoriasis
0.710 0.289 0.000
L40.3 Pustulosis palmaris et plantaris
0.710 0.289 0.000
L40.2 Acrodermatitis continua
0.710 0.289 0.000
L40.1 Generalised pustular psoriasis
0.710 0.289 0.000
L40-L45 Papulosquamous disorders
0.512 0.488 0.001
L43 Lichen planus
0.412 0.588 0.000
L44 Other papulosquamous disorders
0.367 0.632 0.001
L41 Parapsoriasis
0.367 0.632 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.367 0.632 0.001
L42 Pityriasis rosea
0.367 0.632 0.001
L43.9 Lichen planus, unspecified
0.341 0.659 0.000
L43.8 Other lichen planus
0.295 0.704 0.000
L43.3 Subacute (active) lichen planus
0.295 0.704 0.000
L43.2 Lichenoid drug reaction
0.295 0.704 0.000
L43.1 Bullous lichen planus
0.295 0.704 0.000
L43.0 Hypertrophic lichen planus
0.295 0.704 0.000
L41.9 Parapsoriasis, unspecified
0.263 0.736 0.001
L41.8 Other parapsoriasis
0.263 0.736 0.001
L41.5 Retiform parapsoriasis
0.263 0.736 0.001
L41.4 Large plaque parapsoriasis
0.263 0.736 0.001
L41.3 Small plaque parapsoriasis
0.263 0.736 0.001
L41.2 Lymphomatoid papulosis
0.263 0.736 0.001
L41.1 Pityriasis lichenoides chronica
0.263 0.736 0.001
L41.0 Pityriasis lichenoides et varioliformis acuta
0.263 0.736 0.001
L44.9 Papulosquamous disorder, unspecified
0.263 0.736 0.001
L44.8 Other specified papulosquamous disorders
0.263 0.736 0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.263 0.736 0.001
L44.3 Lichen ruber moniliformis
0.263 0.736 0.001
L44.2 Lichen striatus
0.263 0.736 0.001
L44.1 Lichen nitidus
0.263 0.736 0.001
L44.0 Pityriasis rubra pilaris
0.263 0.736 0.001
I63.9 Cerebral infarction, unspecified
0.000 0.761 0.239
I63 Cerebral infarction
0.000 0.766 0.234
I60-I69 Cerebrovascular diseases
0.000 0.776 0.224
I67 Other cerebrovascular diseases
0.000 0.777 0.223
I67.1 Cerebral aneurysm, nonruptured
0.000 0.799 0.201
I67.8 Other specified cerebrovascular diseases
0.000 0.803 0.197
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.803 0.197
I67.2 Cerebral atherosclerosis
0.000 0.804 0.196
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.809 0.191
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.815 0.185
I60 Subarachnoid haemorrhage
0.000 0.815 0.185
I67.9 Cerebrovascular disease, unspecified
0.000 0.816 0.184
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.819 0.181
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.826 0.174
I61 Intracerebral haemorrhage
0.000 0.827 0.173
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.832 0.168
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.832 0.168
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.832 0.168
I65.2 Occlusion and stenosis of carotid artery
0.000 0.832 0.168
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.840 0.160
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.840 0.160
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.840 0.160
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.840 0.160
I67.5 Moyamoya disease
0.000 0.840 0.160
I67.4 Hypertensive encephalopathy
0.000 0.840 0.160
I67.3 Progressive vascular leukoencephalopathy
0.000 0.840 0.160
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.840 0.160
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.848 0.151
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.854 0.146
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.854 0.146
I63.8 Other cerebral infarction
0.000 0.856 0.143
I62 Other nontraumatic intracranial haemorrhage
0.000 0.860 0.140
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.863 0.137
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.863 0.137
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.863 0.137
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.863 0.137
I65.1 Occlusion and stenosis of basilar artery
0.000 0.863 0.137
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.863 0.137
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.864 0.136
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.867 0.133
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.867 0.133
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.867 0.133
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.867 0.133
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.867 0.133
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.871 0.129
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.872 0.128
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.872 0.128
I60.8 Other subarachnoid haemorrhage
0.000 0.874 0.126
I61.8 Other intracerebral haemorrhage
0.000 0.876 0.124
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.876 0.124
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.876 0.124
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.876 0.124
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.876 0.124
I69 Sequelae of cerebrovascular disease
0.000 0.876 0.124
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.885 0.115
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.885 0.115
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.885 0.115
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.885 0.115
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.885 0.115
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.885 0.115
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.885 0.115
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.885 0.115
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.885 0.115
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.885 0.115
I68.0 Cerebral amyloid angiopathy
0.000 0.885 0.115
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.887 0.113
I69.3 Sequelae of cerebral infarction
0.000 0.894 0.106
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.898 0.102
I62.1 Nontraumatic extradural haemorrhage
0.000 0.899 0.101
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.908 0.092
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.911 0.089
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.921 0.079
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.925 0.074
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.927 0.073
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.950 0.050
E10.9 Without complications
0.000 0.960 0.040
E10 Insulin-dependent diabetes mellitus
0.000 0.962 0.038
E10.3 With ophthalmic complications
0.000 0.967 0.033
E10.5 With peripheral circulatory complications
0.000 0.967 0.033
E10.1 With ketoacidosis
0.000 0.968 0.032
E10.2 With renal complications
0.000 0.969 0.031
E10.4 With neurological complications
0.000 0.972 0.028
E10.8 With unspecified complications
0.000 0.972 0.028
E10.7 With multiple complications
0.000 0.972 0.028
E10.6 With other specified complications
0.000 0.972 0.028
E10.0 With coma
0.000 0.972 0.028
H72 Perforation of tympanic membrane
0.000 0.974 0.026
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.974 0.026
H65-H75 Diseases of middle ear and mastoid
0.000 0.976 0.024
E10-E14 Diabetes mellitus
0.000 0.976 0.024
H71 Cholesteatoma of middle ear
0.000 0.976 0.024
H72.0 Central perforation of tympanic membrane
0.000 0.977 0.023
E04.9 Non-toxic goitre, unspecified
0.000 0.978 0.022
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.978 0.022
E00-E07 Disorders of thyroid gland
0.000 0.978 0.022
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.978 0.022
H66 Suppurative and unspecified otitis media
0.000 0.979 0.021
E04 Other non-toxic goitre
0.000 0.979 0.020
H72.8 Other perforations of tympanic membrane
0.000 0.980 0.020
H73 Other disorders of tympanic membrane
0.000 0.980 0.020
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.980 0.020
E14 Unspecified diabetes mellitus
0.000 0.980 0.020
H83.0 Labyrinthitis
0.000 0.981 0.019
H72.2 Other marginal perforations of tympanic membrane
0.000 0.981 0.019
H72.1 Attic perforation of tympanic membrane
0.000 0.981 0.019
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.981 0.019
E70-E90 Metabolic disorders
0.000 0.981 0.019
H70 Mastoiditis and related conditions
0.000 0.982 0.018
H66.3 Other chronic suppurative otitis media
0.000 0.982 0.018
E03 Other hypothyroidism
0.000 0.982 0.018
E05.9 Thyrotoxicosis, unspecified
0.000 0.982 0.018
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.982 0.018
H68 Eustachian salpingitis and obstruction
0.000 0.982 0.018
H67 Otitis media in diseases classified elsewhere
0.000 0.982 0.018
E83 Disorders of mineral metabolism
0.000 0.982 0.018
E12 Malnutrition-related diabetes mellitus
0.000 0.982 0.017
E83.1 Disorders of iron metabolism
0.000 0.983 0.017
H83 Other diseases of inner ear
0.000 0.983 0.017
H74 Other disorders of middle ear and mastoid
0.000 0.983 0.017
Chapter VIII Diseases of the ear and mastoid process
0.000 0.983 0.017
M35.0 Sicca syndrome [Sjogren]
0.000 0.983 0.017
H73.8 Other specified disorders of tympanic membrane
0.000 0.983 0.017
E03.9 Hypothyroidism, unspecified
0.000 0.983 0.017
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.983 0.017
E87.5 Hyperkalaemia
0.000 0.984 0.016
M35.3 Polymyalgia rheumatica
0.000 0.984 0.016
E87.7 Fluid overload
0.000 0.984 0.016
H80-H83 Diseases of inner ear
0.000 0.984 0.016
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.984 0.016
E00 Congenital iodine-deficiency syndrome
0.000 0.984 0.016
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.984 0.016
E14.9 Without complications
0.000 0.984 0.016
E05.8 Other thyrotoxicosis
0.000 0.984 0.016
E05.5 Thyroid crisis or storm
0.000 0.984 0.016
E05.4 Thyrotoxicosis factitia
0.000 0.984 0.016
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.984 0.016
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.984 0.016
E06 Thyroiditis
0.000 0.984 0.015
E14.3 With ophthalmic complications
0.000 0.985 0.015
H66.9 Otitis media, unspecified
0.000 0.985 0.015
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.985 0.015
Chapter XII Diseases of the skin and subcutaneous tissue
0.013 0.985 0.002
M35 Other systemic involvement of connective tissue
0.000 0.985 0.015
H66.4 Suppurative otitis media, unspecified
0.000 0.985 0.015
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.985 0.015
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.985 0.015
H66.0 Acute suppurative otitis media
0.000 0.985 0.015
E04.8 Other specified non-toxic goitre
0.000 0.985 0.015
E87.2 Acidosis
0.000 0.985 0.015
H69 Other disorders of Eustachian tube
0.000 0.985 0.014
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.985 0.014
H73.1 Chronic myringitis
0.000 0.985 0.014
H73.0 Acute myringitis
0.000 0.985 0.014
E14.8 With unspecified complications
0.000 0.986 0.014
E14.7 With multiple complications
0.000 0.986 0.014
E14.6 With other specified complications
0.000 0.986 0.014
E14.5 With peripheral circulatory complications
0.000 0.986 0.014
E14.4 With neurological complications
0.000 0.986 0.014
E14.2 Withrenal complications
0.000 0.986 0.014
E14.1 With ketoacidosis
0.000 0.986 0.014
E14.0 With coma
0.000 0.986 0.014
E73 Lactose intolerance
0.000 0.986 0.014
E04.0 Non-toxic diffuse goitre
0.000 0.986 0.014
H74.0 Tympanosclerosis
0.000 0.986 0.014
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.986 0.014
H65 Nonsuppurative otitis media
0.000 0.986 0.014
E87.3 Alkalosis
0.000 0.986 0.014
E13 Other specified diabetes mellitus
0.000 0.986 0.014
H70.9 Mastoiditis, unspecified
0.000 0.986 0.014
E83.3 Disorders of phosphorus metabolism
0.000 0.986 0.014
E07 Other disorders of thyroid
0.000 0.986 0.014
E88 Other metabolic disorders
0.000 0.986 0.014
E87.4 Mixed disorder of acid-base balance
0.000 0.986 0.014
E74 Other disorders of carbohydrate metabolism
0.000 0.986 0.014
E85 Amyloidosis
0.000 0.986 0.014
E84 Cystic fibrosis
0.000 0.986 0.014
E79 Disorders of purine and pyrimidine metabolism
0.000 0.986 0.014
E77 Disorders of glycoprotein metabolism
0.000 0.986 0.014
E76 Disorders of glycosaminoglycan metabolism
0.000 0.986 0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.986 0.014
E72 Other disorders of amino-acid metabolism
0.000 0.986 0.014
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.986 0.014
E70 Disorders of aromatic amino-acid metabolism
0.000 0.986 0.014
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.986 0.014
H70.8 Other mastoiditis and related conditions
0.000 0.987 0.013
H70.2 Petrositis
0.000 0.987 0.013
H70.1 Chronic mastoiditis
0.000 0.987 0.013
H70.0 Acute mastoiditis
0.000 0.987 0.013
E03.5 Myxoedema coma
0.000 0.987 0.013
E03.4 Atrophy of thyroid (acquired)
0.000 0.987 0.013
E03.3 Postinfectious hypothyroidism
0.000 0.987 0.013
E03.1 Congenital hypothyroidism without goitre
0.000 0.987 0.013
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.987 0.013
E80.4 Gilbert's syndrome
0.000 0.987 0.013
E40-E46 Malnutrition
0.000 0.987 0.013
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.987 0.013
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.987 0.013
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.987 0.013
H68.1 Obstruction of Eustachian tube
0.000 0.987 0.013
H68.0 Eustachian salpingitis
0.000 0.987 0.013
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.987 0.013
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.987 0.013
L50-L54 Urticaria and erythema
0.012 0.987 0.001
E87.0 Hyperosmolality and hypernatraemia
0.000 0.987 0.013
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.987 0.013
E83.8 Other disorders of mineral metabolism
0.000 0.987 0.013
E83.2 Disorders of zinc metabolism
0.000 0.987 0.013
E83.0 Disorders of copper metabolism
0.000 0.987 0.013
E12.9 Without complications
0.000 0.987 0.013
E12.8 With unspecified complications
0.000 0.987 0.013
E12.7 With multiple complications
0.000 0.987 0.013
E12.6 With other specified complications
0.000 0.987 0.013
E12.5 With peripheral circulatory complications
0.000 0.987 0.013
E12.4 With neurological complications
0.000 0.987 0.013
E12.3 With ophthalmic complications
0.000 0.987 0.013
E12.2 With renal complications
0.000 0.987 0.013
E12.1 With ketoacidosis
0.000 0.987 0.013
E12.0 With coma
0.000 0.987 0.013
E87.6 Hypokalaemia
0.000 0.987 0.013
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.987 0.013
H83.9 Disease of inner ear, unspecified
0.000 0.987 0.012
H83.8 Other specified diseases of inner ear
0.000 0.987 0.012
H83.3 Noise effects on inner ear
0.000 0.987 0.012
H83.2 Labyrinthine dysfunction
0.000 0.987 0.012
H83.1 Labyrinthine fistula
0.000 0.987 0.012
E06.3 Autoimmune thyroiditis
0.000 0.988 0.012
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.988 0.012
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.988 0.012
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.988 0.012
H74.1 Adhesive middle ear disease
0.000 0.988 0.012
E20-E35 Disorders of other endocrine glands
0.000 0.988 0.012
H60-H62 Diseases of external ear
0.000 0.988 0.012
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.988 0.012
E83.5 Disorders of calcium metabolism
0.000 0.988 0.012
E83.4 Disorders of magnesium metabolism
0.000 0.988 0.012
L53 Other erythematous conditions
0.011 0.988 0.001
E04.2 Non-toxic multinodular goitre
0.000 0.988 0.012
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.988 0.012
H74.4 Polyp of middle ear
0.000 0.988 0.012
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.988 0.012
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.988 0.011
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.988 0.011
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.988 0.011
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.988 0.011
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.988 0.011
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.988 0.011
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.988 0.011
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.988 0.011
L53.9 Erythematous condition, unspecified
0.011 0.988 0.000
H90-H95 Other disorders of ear
0.000 0.988 0.012
E03.8 Other specified hypothyroidism
0.000 0.989 0.011
M35.7 Hypermobility syndrome
0.000 0.989 0.011
E06.5 Other chronic thyroiditis
0.000 0.989 0.011
E06.4 Drug-induced thyroiditis
0.000 0.989 0.011
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.989 0.011
E06.1 Subacute thyroiditis
0.000 0.989 0.011
E06.0 Acute thyroiditis
0.000 0.989 0.011
H80 Otosclerosis
0.000 0.989 0.011
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.989 0.011
E80.6 Other disorders of bilirubin metabolism
0.000 0.989 0.011
E80.5 Crigler-Najjar syndrome
0.000 0.989 0.011
E80.3 Defects of catalase and peroxydase
0.000 0.989 0.011
E80.2 Other porphyria
0.000 0.989 0.011
E80.1 Porphyria cutanea tarda
0.000 0.989 0.011
E80.0 Hereditary erythropoietic porphyria
0.000 0.989 0.011
E50-E64 Other nutritional deficiencies
0.000 0.989 0.011
L10-L14 Bullous disorders
0.009 0.989 0.002
E28 Ovarian dysfunction
0.000 0.989 0.011
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.989 0.011
M35.8 Other specified systemic involvement of connective tissue
0.000 0.989 0.011
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.989 0.011
M35.5 Multifocal fibrosclerosis
0.000 0.989 0.011
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.989 0.011
M35.2 Behcet's disease
0.000 0.989 0.011
M35.1 Other overlap syndromes
0.000 0.989 0.011
E73.9 Lactose intolerance, unspecified
0.000 0.989 0.011
H65.2 Chronic serous otitis media
0.000 0.989 0.011
H69.8 Other specified disorders of Eustachian tube
0.000 0.989 0.010
H69.0 Patulous Eustachian tube
0.000 0.989 0.010
E28.2 Polycystic ovarian syndrome
0.000 0.989 0.011
E04.1 Non-toxic single thyroid nodule
0.000 0.989 0.010
E73.8 Other lactose intolerance
0.000 0.989 0.010
E73.1 Secondary lactase deficiency
0.000 0.989 0.010
E73.0 Congenital lactase deficiency
0.000 0.989 0.010
E27 Other disorders of adrenal gland
0.000 0.989 0.010
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.990 0.010
H61 Other disorders of external ear
0.000 0.990 0.010
H65.1 Other acute nonsuppurative otitis media
0.000 0.990 0.010
H65.0 Acute serous otitis media
0.000 0.990 0.010
L20-L30 Dermatitis and eczema
0.004 0.990 0.007
E13.8 With unspecified complications
0.000 0.990 0.010
E13.7 With multiple complications
0.000 0.990 0.010
E13.6 With other specified complications
0.000 0.990 0.010
E13.5 With peripheral circulatory complications
0.000 0.990 0.010
E13.4 With neurological complications
0.000 0.990 0.010
E13.3 With ophthalmic complications
0.000 0.990 0.010
E13.2 With renal complications
0.000 0.990 0.010
E13.1 With ketoacidosis
0.000 0.990 0.010
E13.0 With coma
0.000 0.990 0.010
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.990 0.010
E07.1 Dyshormogenetic goitre
0.000 0.990 0.010
E07.0 Hypersecretion of calcitonin
0.000 0.990 0.010
E88.9 Metabolic disorder, unspecified
0.000 0.990 0.010
E88.8 Other specified metabolic disorders
0.000 0.990 0.010
E88.3 Tumour lysis syndrome
0.000 0.990 0.010
E88.2 Lipomatosis, not elsewhere classified
0.000 0.990 0.010
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.990 0.010
E86 Volume depletion
0.000 0.990 0.010
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.990 0.010
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.990 0.010
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.990 0.010
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.990 0.010
E74.2 Disorders of galactose metabolism
0.000 0.990 0.010
E74.1 Disorders of fructose metabolism
0.000 0.990 0.010
E74.0 Glycogen storage disease
0.000 0.990 0.010
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.990 0.010
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.990 0.010
E70.3 Albinism
0.000 0.990 0.010
E70.2 Disorders of tyrosine metabolism
0.000 0.990 0.010
E70.1 Other hyperphenylalaninaemias
0.000 0.990 0.010
E70.0 Classical phenylketonuria
0.000 0.990 0.010
E71.3 Disorders of fatty-acid metabolism
0.000 0.990 0.010
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.990 0.010
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.990 0.010
E71.0 Maple-syrup-urine disease
0.000 0.990 0.010
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.990 0.010
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.990 0.010
E72.5 Disorders of glycine metabolism
0.000 0.990 0.010
E72.4 Disorders of ornithine metabolism
0.000 0.990 0.010
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.990 0.010
E72.2 Disorders of urea cycle metabolism
0.000 0.990 0.010
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.990 0.010
E72.0 Disorders of amino-acid transport
0.000 0.990 0.010
E75.6 Lipid storage disorder, unspecified
0.000 0.990 0.010
E75.5 Other lipid storage disorders
0.000 0.990 0.010
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.990 0.010
E75.3 Sphingolipidosis, unspecified
0.000 0.990 0.010
E75.2 Other sphingolipidosis
0.000 0.990 0.010
E75.1 Other gangliosidosis
0.000 0.990 0.010
E75.0 GM2 gangliosidosis
0.000 0.990 0.010
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.990 0.010
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.990 0.010
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.990 0.010
E76.2 Other mucopolysaccharidoses
0.000 0.990 0.010
E76.1 Mucopolysaccharidosis, type II
0.000 0.990 0.010
E76.0 Mucopolysaccharidosis, type I
0.000 0.990 0.010
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.990 0.010
E77.8 Other disorders of glycoprotein metabolism
0.000 0.990 0.010
E77.1 Defects in glycoprotein degradation
0.000 0.990 0.010
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.990 0.010
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.990 0.010
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.990 0.010
E79.1 Lesch-Nyhan syndrome
0.000 0.990 0.010
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.990 0.010
E84.9 Cystic fibrosis, unspecified
0.000 0.990 0.010
E84.8 Cystic fibrosis with other manifestations
0.000 0.990 0.010
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.990 0.010
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.990 0.010
E85.9 Amyloidosis, unspecified
0.000 0.990 0.010
E85.8 Other amyloidosis
0.000 0.990 0.010
E85.4 Organ-limited amyloidosis
0.000 0.990 0.010
E85.3 Secondary systemic amyloidosis
0.000 0.990 0.010
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.990 0.010
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.990 0.010
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.990 0.010
E27.1 Primary adrenocortical insufficiency
0.000 0.990 0.010
H90 Conductive and sensorineural hearing loss
0.000 0.990 0.010
H93 Other disorders of ear, not elsewhere classified
0.000 0.990 0.010
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.990 0.010
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.990 0.009
E45 Retarded development following protein-energy malnutrition
0.000 0.990 0.009
E43 Unspecified severe protein-energy malnutrition
0.000 0.990 0.009
E42 Marasmic kwashiorkor
0.000 0.990 0.009
E41 Nutritional marasmus
0.000 0.990 0.009
E40 Kwashiorkor
0.000 0.990 0.009
L54 Erythema in diseases classified elsewhere
0.008 0.990 0.001
L51 Erythema multiforme
0.008 0.990 0.001
H65.3 Chronic mucoid otitis media
0.000 0.991 0.009
E11.3 With ophthalmic complications
0.000 0.991 0.009
E11 Non-insulin-dependent diabetes mellitus
0.000 0.991 0.009
E07.8 Other specified disorders of thyroid
0.000 0.991 0.009
E15 Nondiabetic hypoglycaemic coma
0.000 0.991 0.009
E06.9 Thyroiditis, unspecified
0.000 0.991 0.009
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.007 0.991 0.002
H65.4 Other chronic nonsuppurative otitis media
0.000 0.991 0.009
L50 Urticaria
0.008 0.991 0.001
H93.1 Tinnitus
0.000 0.991 0.009
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.991 0.009
E32 Diseases of thymus
0.000 0.991 0.009
E31 Polyglandular dysfunction
0.000 0.991 0.009
E30 Disorders of puberty, not elsewhere classified
0.000 0.991 0.009
E26 Hyperaldosteronism
0.000 0.991 0.009
E20 Hypoparathyroidism
0.000 0.991 0.009
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.991 0.009
E65-E68 Obesity and other hyperalimentation
0.000 0.991 0.009
H61.8 Other specified disorders of external ear
0.000 0.991 0.009
L53.8 Other specified erythematous conditions
0.008 0.991 0.001
L30 Other dermatitis
0.001 0.991 0.008
E07.9 Disorder of thyroid, unspecified
0.000 0.991 0.009
L53.3 Other chronic figurate erythema
0.008 0.991 0.001
L53.2 Erythema marginatum
0.008 0.991 0.001
L53.1 Erythema annulare centrifugum
0.008 0.991 0.001
L53.0 Toxic erythema
0.008 0.991 0.001
L30.9 Dermatitis, unspecified
0.000 0.991 0.009
E29 Testicular dysfunction
0.000 0.991 0.009
L60-L75 Disorders of skin appendages
0.008 0.991 0.001
H61.2 Impacted cerumen
0.000 0.991 0.009
E34 Other endocrine disorders
0.000 0.991 0.008
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.991 0.008
L52 Erythema nodosum
0.007 0.991 0.001
H80.8 Other otosclerosis
0.000 0.992 0.008
H80.2 Cochlear otosclerosis
0.000 0.992 0.008
H80.1 Otosclerosis involving oval window, obliterative
0.000 0.992 0.008
H80.0 Otosclerosis involving oval window, nonobliterative
0.000 0.992 0.008
H90.2 Conductive hearing loss, unspecified
0.000 0.992 0.008
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.992 0.008
E63 Other nutritional deficiencies
0.000 0.992 0.008
E56 Other vitamin deficiencies
0.000 0.992 0.008
E51 Thiamine deficiency
0.000 0.992 0.008
E50 Vitamin A deficiency
0.000 0.992 0.008
E60 Dietary zinc deficiency
0.000 0.992 0.008
E59 Dietary selenium deficiency
0.000 0.992 0.008
E58 Dietary calcium deficiency
0.000 0.992 0.008
E54 Ascorbic acid deficiency
0.000 0.992 0.008
E52 Niacin deficiency [pellagra]
0.000 0.992 0.008
L13 Other bullous disorders
0.007 0.992 0.002
L12 Pemphigoid
0.007 0.992 0.002
L11 Other acantholytic disorders
0.007 0.992 0.002
L10 Pemphigus
0.007 0.992 0.002
L14 Bullous disorders in diseases classified elsewhere
0.007 0.992 0.002
L27 Dermatitis due to substances taken internally
0.002 0.992 0.007
E28.9 Ovarian dysfunction, unspecified
0.000 0.992 0.008
E28.8 Other ovarian dysfunction
0.000 0.992 0.008
E28.3 Primary ovarian failure
0.000 0.992 0.008
E28.1 Androgen excess
0.000 0.992 0.008
E28.0 Oestrogen excess
0.000 0.992 0.008
H90.3 Sensorineural hearing loss, bilateral
0.000 0.992 0.008
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.992 0.008
H61.3 Acquired stenosis of external ear canal
0.000 0.992 0.008
E24 Cushing's syndrome
0.000 0.992 0.008
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.992 0.008
Z12.1 Special screening examination for neoplasm of intestinal tract
0.000 0.992 0.008
E25 Adrenogenital disorders
0.000 0.992 0.008
E46 Unspecified protein-energy malnutrition
0.000 0.992 0.008
E61 Deficiency of other nutrient elements
0.000 0.992 0.008
E27.8 Other specified disorders of adrenal gland
0.000 0.992 0.008
E22 Hyperfunction of pituitary gland
0.000 0.992 0.008
H80.9 Otosclerosis, unspecified
0.000 0.992 0.008
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.008 0.992 0.000
L29 Pruritus
0.002 0.992 0.006
E27.5 Adrenomedullary hyperfunction
0.000 0.992 0.008
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.992 0.008
E27.2 Addisonian crisis
0.000 0.992 0.008
E27.0 Other adrenocortical overactivity
0.000 0.992 0.008
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.992 0.008
E23 Hypofunction and other disorders of pituitary gland
0.000 0.992 0.008
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.992 0.008
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.992 0.007
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.992 0.007
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.992 0.007
E89.5 Postprocedural testicular hypofunction
0.000 0.992 0.007
E89.4 Postprocedural ovarian failure
0.000 0.992 0.007
E89.1 Postprocedural hypoinsulinaemia
0.000 0.992 0.007
H61.9 Disorder of external ear, unspecified
0.000 0.992 0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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