TreeWAS – Variant ID: rs13195402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
N40 Hyperplasia of prostate	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
N40-N51 Diseases of male genital organs	0.000	0.000	1.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	0.000	0.000	1.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.000	1.000
N30-N39 Other diseases of urinary system	0.000	0.000	1.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.000	0.001	0.999
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
K40 Inguinal hernia	0.000	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
M15-M19 Arthrosis	0.999	0.001	0.000
M17 Gonarthrosis [arthrosis of knee]	0.999	0.001	0.000
M35 Other systemic involvement of connective tissue	0.998	0.002	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.998	0.002	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.002	0.998
M35.0 Sicca syndrome [Sjogren]	0.997	0.003	0.000
K44 Diaphragmatic hernia	0.000	0.003	0.997
K40-K46 Hernia	0.000	0.003	0.997
E16 Other disorders of pancreatic internal secretion	0.997	0.003	0.000
H30-H36 Disorders of choroid and retina	0.997	0.003	0.000
N87 Dysplasia of cervix uteri	0.000	0.005	0.995
E16.2 Hypoglycaemia, unspecified	0.995	0.005	0.000
M23 Internal derangement of knee	0.995	0.005	0.000
N81 Female genital prolapse	0.000	0.005	0.995
D80-D89 Certain disorders involving the immune mechanism	0.994	0.006	0.000
N32 Other disorders of bladder	0.000	0.006	0.994
E10.3 With ophthalmic complications	0.994	0.006	0.000
H25-H28 Disorders of lens	0.993	0.007	0.000
M17.9 Gonarthrosis, unspecified	0.993	0.007	0.000
N42 Other disorders of prostate	0.000	0.007	0.993
N81.2 Incomplete uterovaginal prolapse	0.000	0.008	0.992
E11 Non-insulin-dependent diabetes mellitus	0.991	0.009	0.000
N39 Other disorders of urinary system	0.000	0.009	0.991
E05.0 Thyrotoxicosis with diffuse goitre	0.990	0.010	0.000
H26 Other cataract	0.989	0.011	0.000
E20-E35 Disorders of other endocrine glands	0.989	0.011	0.000
D86 Sarcoidosis	0.987	0.013	0.000
E27 Other disorders of adrenal gland	0.986	0.014	0.000
H26.9 Cataract, unspecified	0.986	0.014	0.000
E27.1 Primary adrenocortical insufficiency	0.984	0.016	0.000
M24 Other specific joint derangements	0.984	0.016	0.000
N32.0 Bladder-neck obstruction	0.000	0.016	0.984
N97 Female infertility	0.000	0.016	0.984
M06 Other rheumatoid arthritis	0.983	0.017	0.000
H43-H45 Disorders of vitreous body and globe	0.983	0.017	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.982	0.018	0.000
M06.9 Rheumatoid arthritis, unspecified	0.979	0.021	0.000
E70-E90 Metabolic disorders	0.977	0.023	0.000
D86.9 Sarcoidosis, unspecified	0.975	0.025	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.974	0.026	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.972	0.028	0.000
H36 Retinal disorders in diseases classified elsewhere	0.972	0.028	0.000
E11.9 Without complications	0.971	0.029	0.000
M22 Disorders of patella	0.970	0.030	0.000
N97.9 Female infertility, unspecified	0.000	0.031	0.969
H43 Disorders of vitreous body	0.968	0.032	0.000
M17.1 Other primary gonarthrosis	0.967	0.033	0.000
M31 Other necrotising vasculopathies	0.966	0.034	0.000
N39.8 Other specified disorders of urinary system	0.000	0.035	0.965
M34 Systemic sclerosis	0.965	0.035	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.036	0.964
E10.2 With renal complications	0.964	0.036	0.000
S40-S49 Injuries to the shoulder and upper arm	0.962	0.038	0.000
N87.0 Mild cervical dysplasia	0.000	0.040	0.960
L20-L30 Dermatitis and eczema	0.959	0.041	0.000
M20.1 Hallux valgus (acquired)	0.000	0.041	0.959
H43.1 Vitreous haemorrhage	0.959	0.041	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.955	0.045	0.000
K90 Intestinal malabsorption	0.941	0.046	0.013
H36.0 Diabetic retinopathy	0.954	0.046	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.047	0.953
M23.3 Other meniscus derangements	0.951	0.049	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.049	0.951
M60-M63 Disorders of muscles	0.947	0.053	0.000
N42.8 Other specified disorders of prostate	0.000	0.053	0.947
E10.1 With ketoacidosis	0.945	0.055	0.000
M20 Acquired deformities of fingers and toes	0.002	0.055	0.943
N32.8 Other specified disorders of bladder	0.000	0.061	0.939
S90-S99 Injuries to the ankle and foot	0.937	0.063	0.000
N84 Polyp of female genital tract	0.000	0.063	0.937
M31.6 Other giant cell arteritis	0.934	0.066	0.000
N85.2 Hypertrophy of uterus	0.000	0.068	0.932
L50-L54 Urticaria and erythema	0.931	0.069	0.000
E78.5 Hyperlipidaemia, unspecified	0.931	0.069	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.070	0.930
S46 Injury of muscle and tendon at shoulder and upper arm level	0.930	0.070	0.000
S20-S29 Injuries to the thorax	0.930	0.070	0.000
N39.0 Urinary tract infection, site not specified	0.000	0.070	0.930
H53-H54 Visual disturbances and blindness	0.929	0.071	0.000
Chapter XI Diseases of the digestive system	0.758	0.072	0.169
M07 Psoriatic and enteropathic arthropathies	0.925	0.075	0.000
E14 Unspecified diabetes mellitus	0.925	0.075	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.925	0.075	0.000
L30 Other dermatitis	0.924	0.076	0.000
E11.5 With peripheral circulatory complications	0.923	0.077	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.079	0.921
N84.1 Polyp of cervix uteri	0.000	0.079	0.921
K90-K93 Other diseases of the digestive system	0.765	0.082	0.152
H34 Retinal vascular occlusions	0.915	0.085	0.000
M70-M79 Other soft tissue disorders	0.914	0.086	0.000
E11.3 With ophthalmic complications	0.913	0.087	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.089	0.911
M11 Other crystal arthropathies	0.910	0.090	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.909	0.091	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.906	0.094	0.000
M62 Other disorders of muscle	0.906	0.094	0.000
M72 Fibroblastic disorders	0.903	0.097	0.000
D50-D53 Nutritional anaemias	0.900	0.100	0.000
N48 Other disorders of penis	0.000	0.101	0.899
M24.1 Other articular cartilage disorders	0.898	0.102	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.897	0.103	0.000
H35 Other retinal disorders	0.895	0.105	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.894	0.106	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.893	0.107	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.893	0.107	0.000
L30.9 Dermatitis, unspecified	0.891	0.109	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.890	0.110	0.000
M17.0 Primary gonarthrosis, bilateral	0.889	0.111	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.888	0.112	0.000
M22.3 Other derangements of patella	0.887	0.113	0.000
H26.4 After-cataract	0.887	0.113	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.886	0.114	0.000
L40-L45 Papulosquamous disorders	0.882	0.117	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.882	0.118	0.000
H35.8 Other specified retinal disorders	0.882	0.118	0.000
E50-E64 Other nutritional deficiencies	0.879	0.121	0.000
M34.1 CR(E)ST syndrome	0.878	0.122	0.000
L27 Dermatitis due to substances taken internally	0.877	0.123	0.000
H27 Other disorders of lens	0.877	0.123	0.000
L52 Erythema nodosum	0.876	0.124	0.000
M07.3 Other psoriatic arthropathies	0.873	0.127	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.127	0.873
S21 Open wound of thorax	0.872	0.128	0.000
E10.5 With peripheral circulatory complications	0.871	0.129	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.870	0.130	0.000
E78.1 Pure hyperglyceridaemia	0.868	0.132	0.000
E78.6 Lipoprotein deficiency	0.867	0.132	0.000
M10 Gout	0.867	0.133	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.867	0.133	0.000
N95 Menopausal and other perimenopausal disorders	0.000	0.134	0.866
N34 Urethritis and urethral syndrome	0.000	0.139	0.861
M34.9 Systemic sclerosis, unspecified	0.860	0.140	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.859	0.141	0.000
D50 Iron deficiency anaemia	0.857	0.143	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.857	0.143	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.856	0.144	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.855	0.145	0.000
M62.8 Other specified disorders of muscle	0.852	0.148	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.150	0.850
D55-D59 Haemolytic anaemias	0.849	0.151	0.000
D86.0 Sarcoidosis of lung	0.847	0.153	0.000
M11.2 Other chondrocalcinosis	0.846	0.154	0.000
S92 Fracture of foot, except ankle	0.845	0.155	0.000
H54 Blindness and low vision	0.844	0.156	0.000
S93.1 Dislocation of toe(s)	0.839	0.161	0.000
Chapter II Neoplasms	0.839	0.161	0.000
N48.4 Impotence of organic origin	0.000	0.162	0.838
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.838	0.162	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.837	0.163	0.000
M24.2 Disorder of ligament	0.835	0.165	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.835	0.165	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.834	0.166	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.833	0.167	0.000
S80-S89 Injuries to the knee and lower leg	0.832	0.168	0.000
N30 Cystitis	0.000	0.169	0.831
D69 Purpura and other haemorrhagic conditions	0.828	0.172	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.826	0.174	0.000
E10.4 With neurological complications	0.826	0.174	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.825	0.175	0.000
H31 Other disorders of choroid	0.825	0.175	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.825	0.175	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.825	0.175	0.000
H26.1 Traumatic cataract	0.825	0.175	0.000
M18 Arthrosis of first carpometacarpal joint	0.824	0.176	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.824	0.176	0.000
H46 Optic neuritis	0.824	0.176	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.822	0.178	0.000
N81.8 Other female genital prolapse	0.000	0.178	0.822
L10-L14 Bullous disorders	0.821	0.179	0.000
L28 Lichen simplex chronicus and prurigo	0.820	0.180	0.000
N87.1 Moderate cervical dysplasia	0.000	0.180	0.820
N85.0 Endometrial glandular hyperplasia	0.000	0.181	0.819
M23.9 Internal derangement of knee, unspecified	0.816	0.184	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.816	0.184	0.000
N39.3 Stress incontinence	0.000	0.184	0.816
C43-C44 Melanoma and other malignant neoplasms of skin	0.815	0.185	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.815	0.185	0.000
T79-T79 Certain early complications of trauma	0.813	0.187	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.188	0.812
C43 Malignant melanoma of skin	0.812	0.188	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.811	0.189	0.000
H34.2 Other retinal artery occlusions	0.811	0.189	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.811	0.189	0.000
E10.8 With unspecified complications	0.810	0.190	0.000
M00-M03 Infectious arthropathies	0.810	0.190	0.000
N48.1 Balanoposthitis	0.000	0.194	0.806
E27.3 Drug-induced adrenocortical insufficiency	0.806	0.194	0.000
D50.9 Iron deficiency anaemia, unspecified	0.806	0.194	0.000
M22.8 Other disorders of patella	0.805	0.195	0.000
E14.3 With ophthalmic complications	0.804	0.196	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.196	0.804
N32.1 Vesicointestinal fistula	0.000	0.197	0.803
M07.39 Other psoriatic arthropathies (Site unspecified)	0.802	0.198	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.801	0.199	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.801	0.199	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.800	0.200	0.000
M22.4 Chondromalacia patellae	0.799	0.201	0.000
M76 Enthesopathies of lower limb, excluding foot	0.799	0.201	0.000
L50 Urticaria	0.798	0.202	0.000
M14 Arthropathies in other diseases classified elsewhere	0.797	0.203	0.000
E53 Deficiency of other B group vitamins	0.796	0.204	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.796	0.204	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.796	0.204	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.794	0.206	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.209	0.791
K90.9 Intestinal malabsorption, unspecified	0.783	0.212	0.005
T16 Foreign body in ear	0.788	0.212	0.000
N36 Other disorders of urethra	0.000	0.212	0.788
T00-T07 Injuries involving multiple body regions	0.788	0.212	0.000
E11.6 With other specified complications	0.787	0.213	0.000
D84 Other immunodeficiencies	0.786	0.214	0.000
H27.0 Aphakia	0.785	0.215	0.000
H30 Chorioretinal inflammation	0.785	0.215	0.000
S21.9 Open wound of thorax, part unspecified	0.785	0.215	0.000
E73 Lactose intolerance	0.784	0.215	0.000
M22.2 Patellofemoral disorders	0.784	0.216	0.000
H34.8 Other retinal vascular occlusions	0.782	0.218	0.000
C43.5 Malignant melanoma of trunk	0.782	0.218	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.775	0.218	0.007
C81 Hodgkin's disease	0.781	0.219	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.780	0.219	0.000
E20 Hypoparathyroidism	0.780	0.220	0.000
D50.8 Other iron deficiency anaemias	0.779	0.221	0.000
M17.3 Other posttraumatic gonarthrosis	0.779	0.221	0.000
S20 Superficial injury of thorax	0.778	0.222	0.000
M23.0 Cystic meniscus	0.776	0.224	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.776	0.224	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.775	0.225	0.000
M24.5 Contracture of joint	0.775	0.225	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.775	0.225	0.000
E11.0 With coma	0.774	0.226	0.000
S92.3 Fracture of metatarsal bone	0.774	0.226	0.000
E83 Disorders of mineral metabolism	0.701	0.226	0.073
S80 Superficial injury of lower leg	0.774	0.226	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.773	0.227	0.000
D83 Common variable immunodeficiency	0.772	0.228	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.772	0.228	0.000
N97.1 Female infertility of tubal origin	0.000	0.229	0.771
H53 Visual disturbances	0.770	0.230	0.000
M23.1 Discoid meniscus (congenital)	0.770	0.230	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.769	0.230	0.000
E16.1 Other hypoglycaemia	0.768	0.232	0.000
E10.6 With other specified complications	0.768	0.232	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.767	0.233	0.000
E84 Cystic fibrosis	0.766	0.234	0.000
M62.6 Muscle strain	0.763	0.237	0.000
L40 Psoriasis	0.763	0.237	0.000
N34.2 Other urethritis	0.000	0.239	0.761
M34.8 Other forms of systemic sclerosis	0.761	0.239	0.000
H47.2 Optic atrophy	0.761	0.239	0.000
E27.2 Addisonian crisis	0.761	0.239	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.239	0.761
M86-M90 Other osteopathies	0.760	0.240	0.000
H44 Disorders of globe	0.760	0.240	0.000
E14.9 Without complications	0.760	0.240	0.000
M35.7 Hypermobility syndrome	0.758	0.241	0.000
N42.0 Calculus of prostate	0.000	0.242	0.758
L23 Allergic contact dermatitis	0.758	0.242	0.000
M65-M68 Disorders of synovium and tendon	0.757	0.243	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.756	0.244	0.000
E78.4 Other hyperlipidaemia	0.756	0.244	0.000
D80 Immunodeficiency with predominantly antibody defects	0.755	0.245	0.000
E78.2 Mixed hyperlipidaemia	0.754	0.246	0.000
N91 Absent, scanty and rare menstruation	0.000	0.247	0.753
M18.1 Other primary arthrosis of first carpometacarpal joint	0.753	0.247	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.752	0.248	0.000
H53.1 Subjective visual disturbances	0.751	0.249	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.750	0.250	0.000
M23.5 Chronic instability of knee	0.750	0.250	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.750	0.250	0.000
E10.0 With coma	0.749	0.251	0.000
D86.3 Sarcoidosis of skin	0.749	0.251	0.000
H43.9 Disorder of vitreous body, unspecified	0.748	0.252	0.000
M10.0 Idiopathic gout	0.747	0.253	0.000
K70-K77 Diseases of liver	0.702	0.253	0.045
S21.1 Open wound of front wall of thorax	0.746	0.254	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.254	0.746
M32 Systemic lupus erythematosus	0.746	0.254	0.000
L43 Lichen planus	0.745	0.255	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.744	0.256	0.000
N42.2 Atrophy of prostate	0.000	0.256	0.744
H02 Other disorders of eyelid	0.742	0.258	0.000
H43.8 Other disorders of vitreous body	0.742	0.258	0.000
E88 Other metabolic disorders	0.741	0.259	0.000
H43.2 Crystalline deposits in vitreous body	0.741	0.259	0.000
K46 Unspecified abdominal hernia	0.000	0.260	0.739
N41 Inflammatory diseases of prostate	0.000	0.261	0.739
D61 Other aplastic anaemias	0.738	0.262	0.000
N85.6 Intra-uterine synechiae	0.000	0.265	0.735
K35-K38 Diseases of appendix	0.678	0.265	0.057
S93.0 Dislocation of ankle joint	0.734	0.266	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.732	0.268	0.000
D59 Acquired haemolytic anaemia	0.732	0.268	0.000
E80.4 Gilbert's syndrome	0.731	0.269	0.000
N95.3 States associated with artificial menopause	0.000	0.269	0.731
E23 Hypofunction and other disorders of pituitary gland	0.730	0.270	0.000
M24.26 Disorder of ligament (Lower leg)	0.730	0.270	0.000
N46 Male infertility	0.000	0.270	0.730
N30.2 Other chronic cystitis	0.000	0.271	0.729
D86.8 Sarcoidosis of other and combined sites	0.729	0.271	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.728	0.272	0.000
S43.1 Dislocation of acromioclavicular joint	0.727	0.273	0.000
E13 Other specified diabetes mellitus	0.727	0.273	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.273	0.727
N30.3 Trigonitis	0.000	0.274	0.726
L30.8 Other specified dermatitis	0.726	0.274	0.000
E53.8 Deficiency of other specified B group vitamins	0.725	0.275	0.000
S80.0 Contusion of knee	0.725	0.275	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.725	0.275	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.724	0.276	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.723	0.276	0.000
M76.6 Achilles tendinitis	0.723	0.277	0.000
S92.30 Fracture of metatarsal bone (closed)	0.723	0.277	0.000
Chapter IX Diseases of the circulatory system	0.721	0.279	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.721	0.279	0.000
M24.7 Protrusio acetabuli	0.721	0.279	0.000
E14.2 Withrenal complications	0.721	0.279	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.721	0.279	0.000
D62 Acute posthaemorrhagic anaemia	0.720	0.280	0.000
H47.3 Other disorders of optic disk	0.720	0.280	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.719	0.281	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.719	0.281	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.719	0.281	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.283	0.717
N44 Torsion of testis	0.000	0.283	0.717
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
N37 Urethral disorders in diseases classified elsewhere	0.000	0.283	0.717
N33 Bladder disorders in diseases classified elsewhere	0.000	0.283	0.717
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.283	0.716
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.283	0.716
M12 Other specific arthropathies	0.716	0.284	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284	0.000
M08 Juvenile arthritis	0.716	0.284	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.716	0.284	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.716	0.284	0.000
M24.6 Ankylosis of joint	0.716	0.284	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.716	0.284	0.000
M35.8 Other specified systemic involvement of connective tissue	0.716	0.284	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.716	0.284	0.000
M35.5 Multifocal fibrosclerosis	0.716	0.284	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.716	0.284	0.000
M35.2 Behcet's disease	0.716	0.284	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.284	0.000
N84.9 Polyp of female genital tract, unspecified	0.000	0.285	0.715
K44.1 Diaphragmatic hernia with gangrene	0.000	0.285	0.715
E16.9 Disorder of pancreatic internal secretion, unspecified	0.715	0.285	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.715	0.285	0.000
E16.4 Abnormal secretion of gastrin	0.715	0.285	0.000
E16.3 Increased secretion of glucagon	0.715	0.285	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.715	0.285	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.714	0.285	0.000
D82 Immunodeficiency associated with other major defects	0.713	0.287	0.000
D81 Combined immunodeficiencies	0.713	0.287	0.000
H47.1 Papilloedema, unspecified	0.713	0.287	0.000
N32.4 Rupture of bladder, nontraumatic	0.000	0.287	0.713
N32.2 Vesical fistula, not elsewhere classified	0.000	0.287	0.713
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.712	0.288	0.000
C04 Malignant neoplasm of floor of mouth	0.712	0.288	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.288	0.712
N42.3 Dysplasia of prostate	0.000	0.288	0.712
H02.5 Other disorders affecting eyelid function	0.711	0.289	0.000
N95.0 Postmenopausal bleeding	0.000	0.289	0.711
L27.0 Generalised skin eruption due to drugs and medicaments	0.711	0.289	0.000
M15 Polyarthrosis	0.711	0.289	0.000
E11.7 With multiple complications	0.710	0.289	0.000
N39.2 Orthostatic proteinuria, unspecified	0.000	0.290	0.710
H26.3 Drug-induced cataract	0.709	0.291	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.709	0.291	0.000
E32 Diseases of thymus	0.709	0.291	0.000
E31 Polyglandular dysfunction	0.709	0.291	0.000
E30 Disorders of puberty, not elsewhere classified	0.709	0.291	0.000
E25 Adrenogenital disorders	0.709	0.291	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.708	0.292	0.000
E27.5 Adrenomedullary hyperfunction	0.707	0.293	0.000
E27.0 Other adrenocortical overactivity	0.707	0.293	0.000
H54.7 Unspecified visual loss	0.707	0.293	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.293	0.707
M17.5 Other secondary gonarthrosis	0.706	0.294	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.294	0.706
M24.9 Joint derangement, unspecified	0.706	0.294	0.000
N97.8 Female infertility of other origin	0.000	0.295	0.705
N97.4 Female infertility associated with male factors	0.000	0.295	0.705
N97.3 Female infertility of cervical origin	0.000	0.295	0.705
N97.2 Female infertility of uterine origin	0.000	0.295	0.705
N97.0 Female infertility associated with anovulation	0.000	0.295	0.705
M60 Myositis	0.705	0.295	0.000
M06.8 Other specified rheumatoid arthritis	0.705	0.295	0.000
M06.2 Rheumatoid bursitis	0.705	0.295	0.000
M06.1 Adult-onset Still's disease	0.705	0.295	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.705	0.295	0.000
D69.4 Other primary thrombocytopenia	0.705	0.295	0.000
E03.8 Other specified hypothyroidism	0.705	0.295	0.000
T33-T35 Frostbite	0.704	0.296	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.704	0.296	0.000
N32.3 Diverticulum of bladder	0.000	0.296	0.704
I73 Other peripheral vascular diseases	0.703	0.297	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.703	0.297	0.000
E11.1 With ketoacidosis	0.702	0.297	0.000
E78.8 Other disorders of lipoprotein metabolism	0.702	0.298	0.000
K75 Other inflammatory liver diseases	0.693	0.299	0.008
H54.4 Blindness, one eye	0.701	0.299	0.000
E79 Disorders of purine and pyrimidine metabolism	0.700	0.300	0.000
E77 Disorders of glycoprotein metabolism	0.700	0.300	0.000
E76 Disorders of glycosaminoglycan metabolism	0.700	0.300	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.700	0.300	0.000
E72 Other disorders of amino-acid metabolism	0.700	0.300	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.700	0.300	0.000
E70 Disorders of aromatic amino-acid metabolism	0.700	0.300	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.700	0.300	0.000
H02.6 Xanthelasma of eyelid	0.700	0.300	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.699	0.301	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.698	0.302	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.698	0.302	0.000
D86.1 Sarcoidosis of lymph nodes	0.697	0.303	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.697	0.303	0.000
E78.3 Hyperchylomicronaemia	0.697	0.303	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.697	0.303	0.000
M22.0 Recurrent dislocation of patella	0.696	0.303	0.000
M22.1 Recurrent subluxation of patella	0.696	0.304	0.000
M22.9 Disorder of patella, unspecified	0.696	0.304	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.695	0.305	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.695	0.305	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.695	0.305	0.000
H54.6 Unqualified visual loss, one eye	0.694	0.306	0.000
H43.0 Vitreous prolapse	0.694	0.306	0.000
N81.6 Rectocele	0.000	0.307	0.693
E05.8 Other thyrotoxicosis	0.693	0.307	0.000
M31.9 Necrotising vasculopathy, unspecified	0.692	0.308	0.000
M31.8 Other specified necrotising vasculopathies	0.692	0.308	0.000
M31.7 Microscopic polyangiitis	0.692	0.308	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.692	0.308	0.000
M31.2 Lethal midline granuloma	0.692	0.308	0.000
M31.1 Thrombotic microangiopathy	0.692	0.308	0.000
M31.0 Hypersensitivity angiitis	0.692	0.308	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.692	0.308	0.000
M34.0 Progressive systemic sclerosis	0.692	0.308	0.000
N84.2 Polyp of vagina	0.000	0.308	0.691
M23.4 Loose body in knee	0.691	0.308	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.691	0.309	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.691	0.309	0.000
E34 Other endocrine disorders	0.691	0.309	0.000
E14.1 With ketoacidosis	0.690	0.310	0.000
S48 Traumatic amputation of shoulder and upper arm	0.690	0.310	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.690	0.310	0.000
S44 Injury of nerves at shoulder and upper arm level	0.690	0.310	0.000
S47 Crushing injury of shoulder and upper arm	0.690	0.310	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.690	0.310	0.000
H35.4 Peripheral retinal degeneration	0.689	0.311	0.000
S29 Other and unspecified injuries of thorax	0.689	0.311	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations