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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13200797
log Bayes Factor = 98.3608
Chromosome 6   position 26,122,957  (GRCh37) Explore rs13200797 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
C43 Malignant melanoma of skin
0.999 0.001 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.999 0.001 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
D50 Iron deficiency anaemia
0.998 0.002 0.000
M06 Other rheumatoid arthritis
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E27 Other disorders of adrenal gland
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
D50.9 Iron deficiency anaemia, unspecified
0.997 0.003 0.000
M06.9 Rheumatoid arthritis, unspecified
0.996 0.004 0.000
E27.1 Primary adrenocortical insufficiency
0.994 0.006 0.000
M15-M19 Arthrosis
0.994 0.006 0.000
M17 Gonarthrosis [arthrosis of knee]
0.994 0.006 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.990 0.010 0.000
M24 Other specific joint derangements
0.989 0.011 0.000
M17.9 Gonarthrosis, unspecified
0.989 0.011 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.988 0.012 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.986 0.014 0.000
M35 Other systemic involvement of connective tissue
0.983 0.017 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.982 0.018 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.981 0.019 0.000
M35.0 Sicca syndrome [Sjogren]
0.976 0.024 0.000
C43.5 Malignant melanoma of trunk
0.970 0.030 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.969 0.031 0.000
D50.8 Other iron deficiency anaemias
0.968 0.032 0.000
C15-C26 Malignant neoplasms of digestive organs
0.967 0.033 0.000
M10 Gout
0.967 0.033 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.965 0.035 0.000
M24.1 Other articular cartilage disorders
0.952 0.048 0.000
M34 Systemic sclerosis
0.952 0.048 0.000
M65-M68 Disorders of synovium and tendon
0.952 0.048 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.948 0.052 0.000
O46.9 Antepartum haemorrhage, unspecified
0.945 0.055 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.944 0.056 0.000
E10.3 With ophthalmic complications
0.943 0.057 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.057 0.943
C83.3 Large cell (diffuse)
0.940 0.060 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.935 0.065 0.000
C25 Malignant neoplasm of pancreas
0.935 0.065 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.930 0.070 0.000
K90 Intestinal malabsorption
0.928 0.071 0.001
E10.1 With ketoacidosis
0.928 0.072 0.000
M17.0 Primary gonarthrosis, bilateral
0.927 0.073 0.000
M07 Psoriatic and enteropathic arthropathies
0.927 0.073 0.000
R31 Unspecified haematuria
0.000 0.077 0.923
E14 Unspecified diabetes mellitus
0.920 0.080 0.000
E10.2 With renal complications
0.920 0.080 0.000
E70-E90 Metabolic disorders
0.919 0.081 0.000
M23 Internal derangement of knee
0.919 0.081 0.000
E23 Hypofunction and other disorders of pituitary gland
0.918 0.082 0.000
D80-D89 Certain disorders involving the immune mechanism
0.917 0.083 0.000
C85.1 B-cell lymphoma, unspecified
0.914 0.086 0.000
C43.9 Malignant melanoma of skin, unspecified
0.914 0.086 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.909 0.091 0.000
M86-M90 Other osteopathies
0.908 0.092 0.000
C43.4 Malignant melanoma of scalp and neck
0.907 0.093 0.000
C18 Malignant neoplasm of colon
0.906 0.094 0.000
O44 Placenta praevia
0.906 0.094 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.901 0.099 0.000
L50-L54 Urticaria and erythema
0.901 0.099 0.000
C81 Hodgkin's disease
0.900 0.100 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.898 0.102 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.895 0.105 0.000
M00-M03 Infectious arthropathies
0.893 0.107 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.893 0.107 0.000
C18.9 Colon, unspecified
0.892 0.108 0.000
M10.0 Idiopathic gout
0.891 0.109 0.000
Chapter I Certain infectious and parasitic diseases
0.891 0.109 0.000
M11 Other crystal arthropathies
0.891 0.109 0.000
B35-B49 Mycoses
0.887 0.113 0.000
L20-L30 Dermatitis and eczema
0.887 0.113 0.000
M60-M63 Disorders of muscles
0.886 0.114 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.885 0.115 0.000
O43 Placental disorders
0.884 0.116 0.000
M10.9 Gout, unspecified
0.881 0.119 0.000
B37 Candidiasis
0.880 0.120 0.000
D86 Sarcoidosis
0.877 0.123 0.000
O36 Maternal care for other known or suspected foetal problems
0.876 0.124 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.875 0.125 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.875 0.125 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.874 0.125 0.000
M07.3 Other psoriatic arthropathies
0.874 0.126 0.000
O44.1 Placenta praevia with haemorrhage
0.867 0.133 0.000
E10.5 With peripheral circulatory complications
0.867 0.133 0.000
M22 Disorders of patella
0.865 0.135 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.865 0.135 0.000
M86 Osteomyelitis
0.864 0.136 0.000
L40-L45 Papulosquamous disorders
0.860 0.140 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.143 0.857
B37.0 Candidal stomatitis
0.856 0.144 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.855 0.145 0.000
C25.9 Pancreas, unspecified
0.855 0.145 0.000
L50 Urticaria
0.853 0.147 0.000
M21 Other acquired deformities of limbs
0.851 0.149 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.848 0.152 0.000
M65 Synovitis and tenosynovitis
0.845 0.155 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.840 0.160 0.000
B37.9 Candidiasis, unspecified
0.840 0.160 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.839 0.161 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.838 0.162 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.838 0.162 0.000
C82.2 Large cell, follicular
0.838 0.162 0.000
E83 Disorders of mineral metabolism
0.813 0.162 0.025
K40 Inguinal hernia
0.001 0.162 0.836
M10.07 Idiopathic gout (Ankle and foot)
0.838 0.162 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.837 0.163 0.000
M34.9 Systemic sclerosis, unspecified
0.837 0.163 0.000
C15 Malignant neoplasm of oesophagus
0.835 0.165 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.831 0.169 0.000
L27 Dermatitis due to substances taken internally
0.831 0.169 0.000
D86.9 Sarcoidosis, unspecified
0.830 0.170 0.000
M17.1 Other primary gonarthrosis
0.829 0.171 0.000
B02 Zoster [herpes zoster]
0.829 0.171 0.000
E50-E64 Other nutritional deficiencies
0.828 0.172 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.824 0.176 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.823 0.177 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.816 0.184 0.000
M00 Pyogenic arthritis
0.816 0.184 0.000
M62 Other disorders of muscle
0.815 0.185 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.814 0.186 0.000
M11.2 Other chondrocalcinosis
0.813 0.187 0.000
Chapter VII Diseases of the eye and adnexa
0.812 0.188 0.000
D55-D59 Haemolytic anaemias
0.812 0.188 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.812 0.188 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.812 0.188 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.189 0.811
O60-O75 Complications of labour and delivery
0.811 0.189 0.000
M86.9 Osteomyelitis, unspecified
0.810 0.190 0.000
E23.2 Diabetes insipidus
0.809 0.191 0.000
M06.4 Inflammatory polyarthropathy
0.809 0.191 0.000
M21.0 Valgus deformity, not elsewhere classified
0.809 0.191 0.000
L40 Psoriasis
0.808 0.192 0.000
E10.8 With unspecified complications
0.806 0.194 0.000
M34.8 Other forms of systemic sclerosis
0.806 0.194 0.000
B44 Aspergillosis
0.805 0.195 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.804 0.196 0.000
M34.1 CR(E)ST syndrome
0.804 0.196 0.000
M31 Other necrotising vasculopathies
0.804 0.196 0.000
M66 Spontaneous rupture of synovium and tendon
0.800 0.199 0.000
K90.9 Intestinal malabsorption, unspecified
0.798 0.202 0.000
O43.8 Other placental disorders
0.798 0.202 0.000
M67 Other disorders of synovium and tendon
0.796 0.204 0.000
M14 Arthropathies in other diseases classified elsewhere
0.795 0.205 0.000
C25.0 Head of pancreas
0.792 0.208 0.000
M23.4 Loose body in knee
0.792 0.208 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.791 0.209 0.000
O62 Abnormalities of forces of labour
0.789 0.211 0.000
L50.0 Allergic urticaria
0.789 0.211 0.000
E27.2 Addisonian crisis
0.786 0.214 0.000
C82.0 Small cleaved cell, follicular
0.786 0.214 0.000
E23.7 Disorder of pituitary gland, unspecified
0.785 0.215 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.784 0.215 0.000
M32 Systemic lupus erythematosus
0.783 0.217 0.000
E14.5 With peripheral circulatory complications
0.781 0.219 0.000
C83.7 Burkitt's tumour
0.781 0.219 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.779 0.221 0.000
E78.6 Lipoprotein deficiency
0.779 0.221 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.779 0.221 0.000
E21.0 Primary hyperparathyroidism
0.779 0.221 0.000
M17.3 Other posttraumatic gonarthrosis
0.778 0.222 0.000
M24.0 Loose body in joint
0.778 0.222 0.000
O16 Unspecified maternal hypertension
0.778 0.222 0.000
E78.1 Pure hyperglyceridaemia
0.777 0.223 0.000
E22 Hyperfunction of pituitary gland
0.775 0.225 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.773 0.227 0.000
O73 Retained placenta and membranes, without haemorrhage
0.772 0.228 0.000
C95 Leukaemia of unspecified cell type
0.772 0.228 0.000
E78.2 Mixed hyperlipidaemia
0.772 0.228 0.000
M22.3 Other derangements of patella
0.772 0.228 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.771 0.229 0.000
B02.9 Zoster without complication
0.769 0.231 0.000
L10-L14 Bullous disorders
0.768 0.231 0.000
E10.6 With other specified complications
0.768 0.232 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.768 0.232 0.000
E16.1 Other hypoglycaemia
0.767 0.233 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.765 0.235 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.765 0.235 0.000
O46.8 Other antepartum haemorrhage
0.763 0.236 0.000
C92 Myeloid leukaemia
0.763 0.237 0.000
C23 Malignant neoplasm of gallbladder
0.763 0.237 0.000
M00.9 Pyogenic arthritis, unspecified
0.761 0.239 0.000
L40.0 Psoriasis vulgaris
0.760 0.240 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.760 0.240 0.000
C83.1 Small cleaved cell (diffuse)
0.759 0.241 0.000
C81.9 Hodgkin's disease, unspecified
0.758 0.242 0.000
M35.7 Hypermobility syndrome
0.758 0.242 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.757 0.243 0.000
E14.6 With other specified complications
0.755 0.245 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.755 0.245 0.000
D53 Other nutritional anaemias
0.753 0.247 0.000
L52 Erythema nodosum
0.753 0.247 0.000
M33 Dermatopolymyositis
0.752 0.247 0.000
H53-H54 Visual disturbances and blindness
0.752 0.248 0.000
E20 Hypoparathyroidism
0.750 0.249 0.000
D64.8 Other specified anaemias
0.750 0.250 0.000
L23 Allergic contact dermatitis
0.750 0.250 0.000
E10.0 With coma
0.749 0.251 0.000
O73.0 Retained placenta, without haemorrhage
0.748 0.252 0.000
C25.3 Pancreatic duct
0.748 0.252 0.000
E14.1 With ketoacidosis
0.744 0.256 0.000
E83.5 Disorders of calcium metabolism
0.740 0.258 0.002
D52 Folate deficiency anaemia
0.738 0.261 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.738 0.262 0.000
M23.3 Other meniscus derangements
0.738 0.262 0.000
M10.90 Gout, unspecified (Multiple sites)
0.737 0.263 0.000
H54 Blindness and low vision
0.736 0.264 0.000
E13 Other specified diabetes mellitus
0.735 0.265 0.000
M24.2 Disorder of ligament
0.735 0.265 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.733 0.267 0.000
C15.4 Middle third of oesophagus
0.732 0.268 0.000
A15-A19 Tuberculosis
0.732 0.268 0.000
H43-H45 Disorders of vitreous body and globe
0.731 0.269 0.000
D86.3 Sarcoidosis of skin
0.731 0.269 0.000
C25.2 Tail of pancreas
0.730 0.270 0.000
M10.94 Gout, unspecified (Hand)
0.730 0.270 0.000
M24.7 Protrusio acetabuli
0.730 0.270 0.000
O36.4 Maternal care for intra-uterine death
0.729 0.271 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.727 0.273 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.725 0.275 0.000
M13 Other arthritis
0.725 0.275 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.724 0.276 0.000
E05.8 Other thyrotoxicosis
0.724 0.276 0.000
E88 Other metabolic disorders
0.722 0.278 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.722 0.278 0.000
O62.2 Other uterine inertia
0.721 0.279 0.000
O71 Other obstetric trauma
0.720 0.280 0.000
B02.3 Zoster ocular disease
0.719 0.281 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.719 0.281 0.000
E24 Cushing's syndrome
0.718 0.282 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C93 Monocytic leukaemia
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E31 Polyglandular dysfunction
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
C43.8 Overlapping malignant melanoma of skin
0.716 0.284 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.716 0.284 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.716 0.284 0.000
C43.0 Malignant melanoma of lip
0.716 0.284 0.000
E23.6 Other disorders of pituitary gland
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
M62.8 Other specified disorders of muscle
0.716 0.284 0.000
D50.1 Sideropenic dysphagia
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.285 0.000
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
M06.1 Adult-onset Still's disease
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.715 0.285 0.000
E27.0 Other adrenocortical overactivity
0.715 0.285 0.000
M24.5 Contracture of joint
0.714 0.286 0.000
E34 Other endocrine disorders
0.714 0.286 0.000
L28 Lichen simplex chronicus and prurigo
0.714 0.286 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.713 0.287 0.000
Chapter V Mental and behavioural disorders
0.713 0.287 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.712 0.287 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.712 0.287 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
B44.9 Aspergillosis, unspecified
0.712 0.288 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.712 0.288 0.000
M89 Other disorders of bone
0.710 0.290 0.000
C81.1 Nodular sclerosis
0.709 0.291 0.000
M24.9 Joint derangement, unspecified
0.709 0.291 0.000
M24.6 Ankylosis of joint
0.709 0.291 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.708 0.292 0.000
B02.2 Zoster with other nervous system involvement
0.707 0.293 0.000
O31 Complications specific to multiple gestation
0.707 0.293 0.000
M23.9 Internal derangement of knee, unspecified
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.705 0.295 0.000
M66.3 Spontaneous rupture of flexor tendons
0.705 0.295 0.000
O33 Maternal care for known or suspected disproportion
0.705 0.295 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.704 0.295 0.000
M35.8 Other specified systemic involvement of connective tissue
0.704 0.295 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.704 0.295 0.000
M35.5 Multifocal fibrosclerosis
0.704 0.295 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.704 0.295 0.000
M35.2 Behcet's disease
0.704 0.295 0.000
C82.6 Cutaneous follicle centre lymphoma
0.704 0.296 0.000
C82.5 Diffuse follicle centre lymphoma
0.704 0.296 0.000
C82.4 Follicular lymphoma grade IIIb
0.704 0.296 0.000
C82.3 Follicular lymphoma grade IIIa
0.704 0.296 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.704 0.296 0.000
C85.0 Lymphosarcoma
0.704 0.296 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.703 0.297 0.000
E78.4 Other hyperlipidaemia
0.703 0.297 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.703 0.297 0.000
M22.8 Other disorders of patella
0.703 0.297 0.000
C81.0 Lymphocytic predominance
0.703 0.297 0.000
C18.4 Transverse colon
0.702 0.298 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.702 0.298 0.000
B37.3 Candidiasis of vulva and vagina
0.701 0.299 0.000
M23.49 Loose body in knee-Unspec lig/men
0.701 0.299 0.000
M18 Arthrosis of first carpometacarpal joint
0.701 0.299 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.700 0.300 0.000
M17.5 Other secondary gonarthrosis
0.699 0.300 0.000
M23.8 Other internal derangements of knee
0.700 0.300 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.699 0.301 0.000
D84 Other immunodeficiencies
0.698 0.302 0.000
L50.9 Urticaria, unspecified
0.698 0.302 0.000
M10.96 Gout, unspecified (Lower leg)
0.698 0.302 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.698 0.302 0.000
M62.6 Muscle strain
0.696 0.304 0.000
C18.5 Splenic flexure
0.696 0.304 0.000
L50.1 Idiopathic urticaria
0.695 0.305 0.000
E11 Non-insulin-dependent diabetes mellitus
0.695 0.305 0.000
C83.6 Undifferentiated (diffuse)
0.694 0.305 0.000
C83.5 Lymphoblastic (diffuse)
0.694 0.305 0.000
C83.4 Immunoblastic (diffuse)
0.694 0.305 0.000
C83.2 Mixed small and large cell (diffuse)
0.694 0.305 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.694 0.306 0.000
M10.4 Other secondary gout
0.693 0.307 0.000
M10.3 Gout due to impairment of renal function
0.693 0.307 0.000
M10.2 Drug-induced gout
0.693 0.307 0.000
M10.1 Lead-induced gout
0.693 0.307 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.693 0.307 0.000
H46 Optic neuritis
0.693 0.307 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.692 0.308 0.000
D59 Acquired haemolytic anaemia
0.692 0.308 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.691 0.309 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.691 0.309 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.690 0.310 0.000
C83.0 Small cell (diffuse)
0.689 0.310 0.000
E14.3 With ophthalmic complications
0.689 0.311 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.688 0.311 0.000
B25-B34 Other viral diseases
0.688 0.311 0.000
O36.5 Maternal care for poor foetal growth
0.688 0.312 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.688 0.312 0.000
H43 Disorders of vitreous body
0.687 0.313 0.000
M23.1 Discoid meniscus (congenital)
0.687 0.313 0.000
B00 Herpesviral [herpes simplex] infections
0.687 0.313 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.686 0.314 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.686 0.314 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.685 0.315 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.684 0.315 0.000
M86.6 Other chronic osteomyelitis
0.684 0.316 0.000
O45 Premature separation of placenta [abruptio placentae]
0.684 0.316 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.683 0.317 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.683 0.317 0.000
M24.18 Other articular cartilage disorders (Other)
0.683 0.317 0.000
M24.14 Other articular cartilage disorders (Hand)
0.683 0.317 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.683 0.317 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.683 0.317 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.683 0.317 0.000
M34.0 Progressive systemic sclerosis
0.683 0.317 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.682 0.318 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.682 0.318 0.000
E21.3 Hyperparathyroidism, unspecified
0.682 0.318 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.681 0.318 0.000
C81.2 Mixed cellularity
0.681 0.319 0.000
C18.6 Descending colon
0.680 0.320 0.000
M10.99 Gout, unspecified (Site unspecified)
0.680 0.320 0.000
O85-O92 Complications predominantly related to the puerperium
0.679 0.321 0.000
C15.9 Oesophagus, unspecified
0.679 0.321 0.000
B01 Varicella [chickenpox]
0.678 0.322 0.000
L30 Other dermatitis
0.677 0.323 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.675 0.325 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.675 0.325 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
C25.1 Body of pancreas
0.675 0.325 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.674 0.326 0.000
M65.3 Trigger finger
0.674 0.326 0.000
C07 Malignant neoplasm of parotid gland
0.674 0.326 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.673 0.327 0.000
E73 Lactose intolerance
0.673 0.327 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.672 0.328 0.000
O43.1 Malformation of placenta
0.672 0.328 0.000
M15 Polyarthrosis
0.672 0.328 0.000
D69 Purpura and other haemorrhagic conditions
0.671 0.329 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.670 0.329 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.670 0.329 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.670 0.329 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.670 0.329 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.670 0.329 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.670 0.329 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.670 0.329 0.000
C25.8 Overlapping lesion of pancreas
0.670 0.330 0.000
C25.7 Other parts of pancreas
0.670 0.330 0.000
C25.4 Endocrine pancreas
0.670 0.330 0.000
M86.8 Other osteomyelitis
0.669 0.331 0.000
E83.4 Disorders of magnesium metabolism
0.662 0.331 0.007
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.668 0.332 0.000
L40.3 Pustulosis palmaris et plantaris
0.668 0.332 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.667 0.333 0.000
C92.0 Acute myeloid leukaemia
0.667 0.333 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.666 0.333 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.666 0.334 0.000
K90.3 Pancreatic steatorrhoea
0.665 0.334 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.665 0.334 0.001
K90.1 Tropical sprue
0.665 0.334 0.001
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.665 0.335 0.000
M07.6 Other enteropathic arthropathies
0.664 0.336 0.000
M07.5 Arthropathy in ulcerative colitis
0.664 0.336 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.664 0.336 0.000
M07.2 Psoriatic spondylitis
0.664 0.336 0.000
M07.1 Arthritis mutilans
0.664 0.336 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.664 0.336 0.000
O36.9 Maternal care for foetal problem, unspecified
0.664 0.336 0.000
O62.3 Precipitate labour
0.663 0.337 0.000
E03.8 Other specified hypothyroidism
0.663 0.337 0.000
B37.4 Candidiasis of other urogenital sites
0.663 0.337 0.000
H30-H36 Disorders of choroid and retina
0.663 0.337 0.000
M19 Other arthrosis
0.662 0.338 0.000
O34.0 Maternal care for congenital malformation of uterus
0.662 0.338 0.000
E74 Other disorders of carbohydrate metabolism
0.661 0.339 0.000
H54.0 Blindness, both eyes
0.661 0.339 0.000
B44.1 Other pulmonary aspergillosis
0.660 0.340 0.000
E55 Vitamin D deficiency
0.660 0.340 0.000
E14.8 With unspecified complications
0.660 0.340 0.000
E14.7 With multiple complications
0.660 0.340 0.000
E14.4 With neurological complications
0.660 0.340 0.000
E14.2 Withrenal complications
0.660 0.340 0.000
E14.0 With coma
0.660 0.340 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.660 0.340 0.000
E79 Disorders of purine and pyrimidine metabolism
0.659 0.341 0.000
E77 Disorders of glycoprotein metabolism
0.659 0.341 0.000
E76 Disorders of glycosaminoglycan metabolism
0.659 0.341 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.659 0.341 0.000
E72 Other disorders of amino-acid metabolism
0.659 0.341 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.659 0.341 0.000
E70 Disorders of aromatic amino-acid metabolism
0.659 0.341 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.659 0.341 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.659 0.341 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.658 0.341 0.000
E23.1 Drug-induced hypopituitarism
0.658 0.341 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.658 0.342 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.658 0.342 0.000
D82 Immunodeficiency associated with other major defects
0.657 0.343 0.000
D81 Combined immunodeficiencies
0.657 0.343 0.000
M23.5 Chronic instability of knee
0.657 0.343 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.656 0.344 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.655 0.344 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.655 0.344 0.000
D83 Common variable immunodeficiency
0.655 0.345 0.000
H43.1 Vitreous haemorrhage
0.654 0.346 0.000
L53 Other erythematous conditions
0.651 0.349 0.000
E29 Testicular dysfunction
0.651 0.349 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.650 0.350 0.000
C18.8 Overlapping lesion of colon
0.649 0.350 0.000
C84.5 Other and unspecified T-cell lymphomas
0.649 0.351 0.000
M14.6 Neuropathic arthropathy
0.648 0.352 0.000
C88 Malignant immunoproliferative diseases
0.648 0.352 0.000
E61 Deficiency of other nutrient elements
0.648 0.352 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.647 0.353 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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