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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13208583
log Bayes Factor = 6.51377
Chromosome 6   position 32,800,871  (GRCh37) Explore rs13208583 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.008 0.992
E03.9 Hypothyroidism, unspecified
0.000 0.016 0.984
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
K90.0 Coeliac disease
0.000 0.017 0.983
E03 Other hypothyroidism
0.000 0.018 0.982
E00-E07 Disorders of thyroid gland
0.000 0.019 0.981
E11 Non-insulin-dependent diabetes mellitus
0.000 0.073 0.927
E65-E68 Obesity and other hyperalimentation
0.000 0.082 0.918
E10.4 With neurological complications
0.000 0.132 0.868
E66 Obesity
0.000 0.136 0.864
E11.3 With ophthalmic complications
0.000 0.138 0.862
E10.1 With ketoacidosis
0.000 0.139 0.861
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.165 0.835
E10.5 With peripheral circulatory complications
0.000 0.174 0.826
J45.9 Asthma, unspecified
0.000 0.181 0.819
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.184 0.816
E66.9 Obesity, unspecified
0.000 0.192 0.808
E11.9 Without complications
0.000 0.218 0.782
E14 Unspecified diabetes mellitus
0.000 0.230 0.770
E40-E46 Malnutrition
0.000 0.231 0.769
E07 Other disorders of thyroid
0.000 0.234 0.766
E11.5 With peripheral circulatory complications
0.000 0.237 0.763
E16 Other disorders of pancreatic internal secretion
0.000 0.272 0.728
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.714
E11.1 With ketoacidosis
0.000 0.294 0.706
E03.5 Myxoedema coma
0.000 0.296 0.704
E03.4 Atrophy of thyroid (acquired)
0.000 0.296 0.704
E03.3 Postinfectious hypothyroidism
0.000 0.296 0.704
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.296 0.704
E03.1 Congenital hypothyroidism without goitre
0.000 0.296 0.704
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.296 0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.296 0.703
E00 Congenital iodine-deficiency syndrome
0.000 0.296 0.703
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.296 0.703
E66.8 Other obesity
0.000 0.302 0.698
E65 Localised adiposity
0.000 0.307 0.693
E05.9 Thyrotoxicosis, unspecified
0.000 0.323 0.677
E11.8 With unspecified complications
0.000 0.335 0.665
E11.7 With multiple complications
0.000 0.335 0.665
E13 Other specified diabetes mellitus
0.000 0.338 0.662
E67 Other hyperalimentation
0.000 0.342 0.658
E68 Sequelae of hyperalimentation
0.000 0.342 0.658
E14.3 With ophthalmic complications
0.000 0.343 0.657
E16.2 Hypoglycaemia, unspecified
0.000 0.348 0.652
E11.0 With coma
0.000 0.355 0.645
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.364 0.636
E07.9 Disorder of thyroid, unspecified
0.000 0.368 0.632
E11.4 With neurological complications
0.000 0.370 0.630
E50-E64 Other nutritional deficiencies
0.000 0.374 0.626
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.380 0.620
E66.1 Drug-induced obesity
0.000 0.380 0.620
E66.0 Obesity due to excess calories
0.000 0.380 0.620
E46 Unspecified protein-energy malnutrition
0.000 0.385 0.615
E15 Nondiabetic hypoglycaemic coma
0.000 0.401 0.598
E06 Thyroiditis
0.000 0.406 0.594
E11.6 With other specified complications
0.000 0.414 0.585
E05.8 Other thyrotoxicosis
0.000 0.415 0.585
E05.5 Thyroid crisis or storm
0.000 0.415 0.585
E05.4 Thyrotoxicosis factitia
0.000 0.415 0.585
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.415 0.585
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.415 0.585
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.439 0.561
E14.8 With unspecified complications
0.000 0.448 0.552
E14.7 With multiple complications
0.000 0.448 0.552
E14.6 With other specified complications
0.000 0.448 0.552
E14.5 With peripheral circulatory complications
0.000 0.448 0.552
E14.4 With neurological complications
0.000 0.448 0.552
E14.2 Withrenal complications
0.000 0.448 0.552
E14.1 With ketoacidosis
0.000 0.448 0.552
E14.0 With coma
0.000 0.448 0.552
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.449 0.551
E45 Retarded development following protein-energy malnutrition
0.000 0.449 0.551
E43 Unspecified severe protein-energy malnutrition
0.000 0.449 0.551
E42 Marasmic kwashiorkor
0.000 0.449 0.551
E41 Nutritional marasmus
0.000 0.449 0.551
E40 Kwashiorkor
0.000 0.449 0.551
E07.1 Dyshormogenetic goitre
0.000 0.451 0.549
E07.0 Hypersecretion of calcitonin
0.000 0.451 0.549
E03.8 Other specified hypothyroidism
0.000 0.456 0.544
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.478 0.522
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.478 0.522
E16.4 Abnormal secretion of gastrin
0.000 0.478 0.522
E16.3 Increased secretion of glucagon
0.000 0.478 0.522
E16.1 Other hypoglycaemia
0.000 0.478 0.522
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.478 0.522
E07.8 Other specified disorders of thyroid
0.000 0.484 0.516
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E11.2 With renal complications
0.000 0.491 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.495 0.504
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.495 0.504
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.495 0.504
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.495 0.504
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.495 0.504
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.495 0.504
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.495 0.504
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.495 0.504
J45 Asthma
0.000 0.510 0.490
E61 Deficiency of other nutrient elements
0.000 0.512 0.488
E13.8 With unspecified complications
0.000 0.525 0.475
E13.7 With multiple complications
0.000 0.525 0.475
E13.6 With other specified complications
0.000 0.525 0.475
E13.5 With peripheral circulatory complications
0.000 0.525 0.475
E13.4 With neurological complications
0.000 0.525 0.475
E13.3 With ophthalmic complications
0.000 0.525 0.475
E13.2 With renal complications
0.000 0.525 0.475
E13.1 With ketoacidosis
0.000 0.525 0.475
E13.0 With coma
0.000 0.525 0.475
E67.8 Other specified hyperalimentation
0.000 0.528 0.472
E67.3 Hypervitaminosis D
0.000 0.528 0.472
E67.2 Megavitamin-B6 syndrome
0.000 0.528 0.472
E67.1 Hypercarotenaemia
0.000 0.528 0.472
E67.0 Hypervitaminosis A
0.000 0.528 0.472
E14.9 Without complications
0.000 0.542 0.458
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.551 0.449
E63 Other nutritional deficiencies
0.000 0.551 0.449
E56 Other vitamin deficiencies
0.000 0.551 0.449
E51 Thiamine deficiency
0.000 0.551 0.449
E50 Vitamin A deficiency
0.000 0.551 0.449
E60 Dietary zinc deficiency
0.000 0.551 0.449
E59 Dietary selenium deficiency
0.000 0.551 0.449
E58 Dietary calcium deficiency
0.000 0.551 0.449
E54 Ascorbic acid deficiency
0.000 0.551 0.449
E52 Niacin deficiency [pellagra]
0.000 0.551 0.449
E06.5 Other chronic thyroiditis
0.000 0.574 0.426
E06.4 Drug-induced thyroiditis
0.000 0.574 0.426
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.574 0.426
E06.1 Subacute thyroiditis
0.000 0.574 0.426
E06.0 Acute thyroiditis
0.000 0.574 0.426
E13.9 Without complications
0.000 0.577 0.423
E53 Deficiency of other B group vitamins
0.000 0.598 0.402
E44.1 Mild protein-energy malnutrition
0.000 0.605 0.395
E44.0 Moderate protein-energy malnutrition
0.000 0.605 0.395
E61.1 Iron deficiency
0.000 0.610 0.390
J45.0 Predominantly allergic asthma
0.000 0.612 0.388
E06.3 Autoimmune thyroiditis
0.000 0.613 0.386
E06.9 Thyroiditis, unspecified
0.000 0.631 0.369
E55 Vitamin D deficiency
0.000 0.633 0.366
K90 Intestinal malabsorption
0.000 0.637 0.363
J45.8 Mixed asthma
0.000 0.649 0.351
J45.1 Nonallergic asthma
0.000 0.649 0.351
E61.9 Deficiency of nutrient element, unspecified
0.000 0.650 0.350
E61.8 Deficiency of other specified nutrient elements
0.000 0.650 0.350
E61.7 Deficiency of multiple nutrient elements
0.000 0.650 0.350
E61.6 Vanadium deficiency
0.000 0.650 0.350
E61.5 Molybdenum deficiency
0.000 0.650 0.350
E61.4 Chromium deficiency
0.000 0.650 0.350
E61.3 Manganese deficiency
0.000 0.650 0.350
E61.2 Magnesium deficiency
0.000 0.650 0.350
E61.0 Copper deficiency
0.000 0.650 0.350
E50.9 Vitamin A deficiency, unspecified
0.000 0.678 0.322
E50.8 Other manifestations of vitamin A deficiency
0.000 0.678 0.322
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.678 0.322
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.678 0.322
E50.5 Vitamin A deficiency with night blindness
0.000 0.678 0.322
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.678 0.322
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.678 0.322
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.678 0.322
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.678 0.322
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.678 0.322
E51.9 Thiamine deficiency, unspecified
0.000 0.678 0.322
E51.8 Other manifestations of thiamine deficiency
0.000 0.678 0.322
E51.2 Wernicke's encephalopathy
0.000 0.678 0.322
E51.1 Beriberi
0.000 0.678 0.322
E56.9 Vitamin deficiency, unspecified
0.000 0.678 0.322
E56.8 Deficiency of other vitamins
0.000 0.678 0.322
E56.1 Deficiency of vitamin K
0.000 0.678 0.322
E56.0 Deficiency of vitamin E
0.000 0.678 0.322
E63.9 Nutritional deficiency, unspecified
0.000 0.678 0.322
E63.8 Other specified nutritional deficiencies
0.000 0.678 0.322
E63.1 Imbalance of constituents of food intake
0.000 0.678 0.322
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.678 0.322
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.678 0.322
E64.8 Sequelae of other nutritional deficiencies
0.000 0.678 0.322
E64.3 Sequelae of rickets
0.000 0.678 0.322
E64.2 Sequelae of vitamin C deficiency
0.000 0.678 0.322
E64.1 Sequelae of vitamin A deficiency
0.000 0.678 0.322
E64.0 Sequelae of protein-energy malnutrition
0.000 0.678 0.322
E53.9 Vitamin B deficiency, unspecified
0.000 0.712 0.288
E53.1 Pyridoxine deficiency
0.000 0.712 0.288
E53.0 Riboflavin deficiency
0.000 0.712 0.288
E55.0 Rickets, active
0.000 0.737 0.263
H35.3 Degeneration of macula and posterior pole
0.000 0.738 0.262
K90.8 Other intestinal malabsorption
0.000 0.739 0.260
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.739 0.260
K90.3 Pancreatic steatorrhoea
0.000 0.739 0.260
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.739 0.260
K90.1 Tropical sprue
0.000 0.739 0.260
H36.0 Diabetic retinopathy
0.000 0.749 0.251
E53.8 Deficiency of other specified B group vitamins
0.000 0.759 0.241
H36 Retinal disorders in diseases classified elsewhere
0.000 0.767 0.233
H35 Other retinal disorders
0.000 0.767 0.233
E70-E90 Metabolic disorders
0.000 0.768 0.232
K90.9 Intestinal malabsorption, unspecified
0.000 0.779 0.221
H30-H36 Disorders of choroid and retina
0.000 0.780 0.220
E83 Disorders of mineral metabolism
0.000 0.801 0.199
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.811 0.189
H35.6 Retinal haemorrhage
0.000 0.815 0.185
E55.9 Vitamin D deficiency, unspecified
0.000 0.820 0.180
H35.8 Other specified retinal disorders
0.000 0.824 0.176
H35.5 Hereditary retinal dystrophy
0.000 0.830 0.170
H35.9 Retinal disorder, unspecified
0.000 0.831 0.169
E83.4 Disorders of magnesium metabolism
0.000 0.831 0.169
J40-J47 Chronic lower respiratory diseases
0.000 0.832 0.168
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.833 0.167
H35.1 Retinopathy of prematurity
0.000 0.833 0.167
E84 Cystic fibrosis
0.000 0.834 0.166
E79 Disorders of purine and pyrimidine metabolism
0.000 0.834 0.166
E77 Disorders of glycoprotein metabolism
0.000 0.834 0.166
E76 Disorders of glycosaminoglycan metabolism
0.000 0.834 0.166
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.834 0.166
E72 Other disorders of amino-acid metabolism
0.000 0.834 0.166
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.834 0.166
E70 Disorders of aromatic amino-acid metabolism
0.000 0.834 0.166
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.834 0.166
E73 Lactose intolerance
0.000 0.836 0.164
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.836 0.164
E88 Other metabolic disorders
0.000 0.838 0.162
H35.7 Separation of retinal layers
0.000 0.839 0.161
E04 Other non-toxic goitre
0.012 0.839 0.149
E83.1 Disorders of iron metabolism
0.000 0.841 0.159
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.842 0.158
H31 Other disorders of choroid
0.000 0.842 0.158
H30 Chorioretinal inflammation
0.000 0.842 0.158
E85 Amyloidosis
0.000 0.845 0.155
E74 Other disorders of carbohydrate metabolism
0.000 0.846 0.154
E89.2 Postprocedural hypoparathyroidism
0.000 0.848 0.152
J40 Bronchitis, not specified as acute or chronic
0.000 0.850 0.150
H35.2 Other proliferative retinopathy
0.000 0.851 0.148
H35.0 Background retinopathy and retinal vascular changes
0.000 0.853 0.147
E89.0 Postprocedural hypothyroidism
0.000 0.854 0.146
E83.3 Disorders of phosphorus metabolism
0.000 0.854 0.146
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.857 0.143
E83.8 Other disorders of mineral metabolism
0.000 0.857 0.143
E83.2 Disorders of zinc metabolism
0.000 0.857 0.143
E83.0 Disorders of copper metabolism
0.000 0.857 0.143
H34 Retinal vascular occlusions
0.000 0.858 0.142
E20-E35 Disorders of other endocrine glands
0.002 0.861 0.137
E83.5 Disorders of calcium metabolism
0.000 0.864 0.136
J46 Status asthmaticus
0.000 0.864 0.136
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.865 0.135
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.865 0.135
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.865 0.135
E89.5 Postprocedural testicular hypofunction
0.000 0.865 0.135
E89.4 Postprocedural ovarian failure
0.000 0.865 0.135
E89.1 Postprocedural hypoinsulinaemia
0.000 0.865 0.135
E89.3 Postprocedural hypopituitarism
0.000 0.868 0.132
H35.4 Peripheral retinal degeneration
0.000 0.872 0.128
J47 Bronchiectasis
0.000 0.877 0.123
J41 Simple and mucopurulent chronic bronchitis
0.000 0.880 0.120
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.881 0.119
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.881 0.119
E70.3 Albinism
0.000 0.881 0.119
E70.2 Disorders of tyrosine metabolism
0.000 0.881 0.119
E70.1 Other hyperphenylalaninaemias
0.000 0.881 0.119
E70.0 Classical phenylketonuria
0.000 0.881 0.119
E71.3 Disorders of fatty-acid metabolism
0.000 0.881 0.119
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.881 0.119
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.881 0.119
E71.0 Maple-syrup-urine disease
0.000 0.881 0.119
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.881 0.119
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.881 0.119
E72.5 Disorders of glycine metabolism
0.000 0.881 0.119
E72.4 Disorders of ornithine metabolism
0.000 0.881 0.119
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.881 0.119
E72.2 Disorders of urea cycle metabolism
0.000 0.881 0.119
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.881 0.119
E72.0 Disorders of amino-acid transport
0.000 0.881 0.119
E75.6 Lipid storage disorder, unspecified
0.000 0.881 0.119
E75.5 Other lipid storage disorders
0.000 0.881 0.119
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.881 0.119
E75.3 Sphingolipidosis, unspecified
0.000 0.881 0.119
E75.2 Other sphingolipidosis
0.000 0.881 0.119
E75.1 Other gangliosidosis
0.000 0.881 0.119
E75.0 GM2 gangliosidosis
0.000 0.881 0.119
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.881 0.119
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.881 0.119
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.881 0.119
E76.2 Other mucopolysaccharidoses
0.000 0.881 0.119
E76.1 Mucopolysaccharidosis, type II
0.000 0.881 0.119
E76.0 Mucopolysaccharidosis, type I
0.000 0.881 0.119
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.881 0.119
E77.8 Other disorders of glycoprotein metabolism
0.000 0.881 0.119
E77.1 Defects in glycoprotein degradation
0.000 0.881 0.119
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.881 0.119
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.881 0.119
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.881 0.119
E79.1 Lesch-Nyhan syndrome
0.000 0.881 0.119
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.881 0.119
E84.9 Cystic fibrosis, unspecified
0.000 0.881 0.119
E84.8 Cystic fibrosis with other manifestations
0.000 0.881 0.119
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.881 0.119
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.881 0.119
E73.8 Other lactose intolerance
0.000 0.882 0.118
E73.1 Secondary lactase deficiency
0.000 0.882 0.118
E73.0 Congenital lactase deficiency
0.000 0.882 0.118
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.882 0.117
E80.6 Other disorders of bilirubin metabolism
0.000 0.882 0.117
E80.5 Crigler-Najjar syndrome
0.000 0.882 0.117
E80.3 Defects of catalase and peroxydase
0.000 0.882 0.117
E80.2 Other porphyria
0.000 0.882 0.117
E80.1 Porphyria cutanea tarda
0.000 0.882 0.117
E80.0 Hereditary erythropoietic porphyria
0.000 0.882 0.117
E88.9 Metabolic disorder, unspecified
0.000 0.883 0.116
E88.8 Other specified metabolic disorders
0.000 0.883 0.116
E88.3 Tumour lysis syndrome
0.000 0.883 0.116
E88.2 Lipomatosis, not elsewhere classified
0.000 0.883 0.116
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.883 0.116
E73.9 Lactose intolerance, unspecified
0.000 0.884 0.116
E04.8 Other specified non-toxic goitre
0.009 0.884 0.107
E80.4 Gilbert's syndrome
0.000 0.885 0.115
H30.9 Chorioretinal inflammation, unspecified
0.000 0.886 0.113
H30.8 Other chorioretinal inflammations
0.000 0.886 0.113
H30.2 Posterior cyclitis
0.000 0.886 0.113
H30.1 Disseminated chorioretinal inflammation
0.000 0.886 0.113
H30.0 Focal chorioretinal inflammation
0.000 0.886 0.113
H31.9 Disorder of choroid, unspecified
0.000 0.886 0.113
H31.8 Other specified disorders of choroid
0.000 0.886 0.113
H31.4 Choroidal detachment
0.000 0.886 0.113
H31.3 Choroidal haemorrhage and rupture
0.000 0.886 0.113
H31.2 Hereditary choroidal dystrophy
0.000 0.886 0.113
H31.1 Choroidal degeneration
0.000 0.886 0.113
H31.0 Chorioretinal scars
0.000 0.886 0.113
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.886 0.113
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.886 0.113
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.887 0.113
H34.8 Other retinal vascular occlusions
0.000 0.888 0.112
E85.8 Other amyloidosis
0.000 0.888 0.111
E85.4 Organ-limited amyloidosis
0.000 0.888 0.111
E85.3 Secondary systemic amyloidosis
0.000 0.888 0.111
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.888 0.111
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.888 0.111
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.888 0.111
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.889 0.110
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.889 0.110
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.889 0.110
E74.2 Disorders of galactose metabolism
0.000 0.889 0.110
E74.1 Disorders of fructose metabolism
0.000 0.889 0.110
E74.0 Glycogen storage disease
0.000 0.889 0.110
E04.0 Non-toxic diffuse goitre
0.009 0.893 0.098
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.894 0.106
E34 Other endocrine disorders
0.001 0.897 0.101
H34.9 Retinal vascular occlusion, unspecified
0.000 0.898 0.102
H34.0 Transient retinal artery occlusion
0.000 0.898 0.102
J33 Nasal polyp
0.000 0.899 0.101
J33.9 Nasal polyp, unspecified
0.000 0.899 0.101
E85.9 Amyloidosis, unspecified
0.000 0.899 0.100
E35 Disorders of endocrine glands in diseases classified elsewhere
0.002 0.900 0.098
E32 Diseases of thymus
0.002 0.900 0.098
E31 Polyglandular dysfunction
0.002 0.900 0.098
E30 Disorders of puberty, not elsewhere classified
0.002 0.900 0.098
E25 Adrenogenital disorders
0.002 0.900 0.098
E20 Hypoparathyroidism
0.002 0.900 0.098
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.901 0.098
J33.8 Other polyp of sinus
0.000 0.903 0.097
E28 Ovarian dysfunction
0.001 0.903 0.095
E22 Hyperfunction of pituitary gland
0.001 0.904 0.095
E24 Cushing's syndrome
0.002 0.905 0.093
E29 Testicular dysfunction
0.002 0.910 0.088
J33.0 Polyp of nasal cavity
0.000 0.910 0.090
E04.9 Non-toxic goitre, unspecified
0.008 0.911 0.081
E26 Hyperaldosteronism
0.002 0.911 0.087
H34.1 Central retinal artery occlusion
0.000 0.911 0.088
J42 Unspecified chronic bronchitis
0.000 0.912 0.087
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.913 0.086
J41.1 Mucopurulent chronic bronchitis
0.000 0.913 0.086
J41.0 Simple chronic bronchitis
0.000 0.913 0.086
E87.5 Hyperkalaemia
0.000 0.914 0.086
H34.2 Other retinal artery occlusions
0.000 0.915 0.085
J32.9 Chronic sinusitis, unspecified
0.000 0.916 0.084
J32 Chronic sinusitis
0.000 0.917 0.083
J30-J39 Other diseases of upper respiratory tract
0.000 0.919 0.081
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.920 0.080
Chapter X Diseases of the respiratory system
0.000 0.922 0.078
E34.9 Endocrine disorder, unspecified
0.001 0.923 0.076
E87.6 Hypokalaemia
0.000 0.924 0.076
E87.4 Mixed disorder of acid-base balance
0.000 0.924 0.076
E87.7 Fluid overload
0.000 0.924 0.076
E87.0 Hyperosmolality and hypernatraemia
0.000 0.925 0.075
J43 Emphysema
0.001 0.925 0.074
E87.2 Acidosis
0.000 0.926 0.074
E34.8 Other specified endocrine disorders
0.001 0.926 0.073
E34.5 Androgen resistance syndrome
0.001 0.926 0.073
E34.4 Constitutional tall stature
0.001 0.926 0.073
E34.3 Short stature, not elsewhere classified
0.001 0.926 0.073
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.926 0.073
E34.1 Other hypersecretion of intestinal hormones
0.001 0.926 0.073
E34.0 Carcinoid syndrome
0.001 0.926 0.073
J33.1 Polypoid sinus degeneration
0.000 0.927 0.073
E20.9 Hypoparathyroidism, unspecified
0.001 0.928 0.070
E20.8 Other hypoparathyroidism
0.001 0.928 0.070
E20.1 Pseudohypoparathyroidism
0.001 0.928 0.070
E20.0 Idiopathic hypoparathyroidism
0.001 0.928 0.070
E25.9 Adrenogenital disorder, unspecified
0.001 0.928 0.070
E25.8 Other adrenogenital disorders
0.001 0.928 0.070
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.928 0.070
E30.9 Disorder of puberty, unspecified
0.001 0.928 0.070
E30.8 Other disorders of puberty
0.001 0.928 0.070
E30.1 Precocious puberty
0.001 0.928 0.070
E30.0 Delayed puberty
0.001 0.928 0.070
E31.9 Polyglandular dysfunction, unspecified
0.001 0.928 0.070
E31.8 Other polyglandular dysfunction
0.001 0.928 0.070
E31.1 Polyglandular hyperfunction
0.001 0.928 0.070
E31.0 Autoimmune polyglandular failure
0.001 0.928 0.070
E32.9 Disease of thymus, unspecified
0.001 0.928 0.070
E32.8 Other diseases of thymus
0.001 0.928 0.070
E32.1 Abscess of thymus
0.001 0.928 0.070
E32.0 Persistent hyperplasia of thymus
0.001 0.928 0.070
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.928 0.070
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.928 0.070
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.928 0.070
E27 Other disorders of adrenal gland
0.002 0.929 0.069
E28.9 Ovarian dysfunction, unspecified
0.001 0.931 0.068
E28.8 Other ovarian dysfunction
0.001 0.931 0.068
E28.3 Primary ovarian failure
0.001 0.931 0.068
E28.1 Androgen excess
0.001 0.931 0.068
E28.0 Oestrogen excess
0.001 0.931 0.068
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.931 0.068
E22.8 Other hyperfunction of pituitary gland
0.001 0.931 0.068
E22.1 Hyperprolactinaemia
0.001 0.931 0.068
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.001 0.931 0.067
J32.4 Chronic pansinusitis
0.000 0.931 0.069
E24.8 Other Cushing's syndrome
0.001 0.932 0.067
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.932 0.067
E24.3 Ectopic ACTH syndrome
0.001 0.932 0.067
E24.2 Drug-induced Cushing's syndrome
0.001 0.932 0.067
E24.1 Nelson's syndrome
0.001 0.932 0.067
E24.0 Pituitary-dependent Cushing's disease
0.001 0.932 0.067
E22.0 Acromegaly and pituitary gigantism
0.001 0.932 0.067
J60-J70 Lung diseases due to external agents
0.000 0.933 0.066
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.934 0.065
E28.2 Polycystic ovarian syndrome
0.001 0.934 0.065
J32.8 Other chronic sinusitis
0.000 0.934 0.065
J32.2 Chronic ethmoidal sinusitis
0.000 0.935 0.065
E29.9 Testicular dysfunction, unspecified
0.001 0.935 0.064
E29.8 Other testicular dysfunction
0.001 0.935 0.064
E29.0 Testicular hyperfunction
0.001 0.935 0.064
E86 Volume depletion
0.000 0.936 0.064
E26.9 Hyperaldosteronism, unspecified
0.001 0.936 0.063
E26.8 Other hyperaldosteronism
0.001 0.936 0.063
E26.1 Secondary hyperaldosteronism
0.001 0.936 0.063
E24.9 Cushing's syndrome, unspecified
0.001 0.937 0.062
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.938 0.062
J37 Chronic laryngitis and laryngotracheitis
0.000 0.938 0.062
J69 Pneumonitis due to solids and liquids
0.000 0.938 0.062
E04.1 Non-toxic single thyroid nodule
0.011 0.938 0.051
J00-J06 Acute upper respiratory infections
0.000 0.939 0.061
J32.3 Chronic sphenoidal sinusitis
0.000 0.940 0.059
J32.1 Chronic frontal sinusitis
0.000 0.940 0.059
J69.0 Pneumonitis due to food and vomit
0.000 0.942 0.058
M06.9 Rheumatoid arthritis, unspecified
0.000 0.944 0.056
E87.3 Alkalosis
0.000 0.944 0.056
J95-J99 Other diseases of the respiratory system
0.000 0.944 0.056
E29.1 Testicular hypofunction
0.001 0.945 0.054
J43.2 Centrilobular emphysema
0.001 0.946 0.053
J43.8 Other emphysema
0.001 0.946 0.053
J43.1 Panlobular emphysema
0.001 0.946 0.053
J43.0 MacLeod's syndrome
0.001 0.946 0.053
J02 Acute pharyngitis
0.000 0.947 0.053
E26.0 Primary hyperaldosteronism
0.002 0.947 0.051
E27.5 Adrenomedullary hyperfunction
0.001 0.949 0.050
E27.2 Addisonian crisis
0.001 0.949 0.050
E27.0 Other adrenocortical overactivity
0.001 0.949 0.050
E27.1 Primary adrenocortical insufficiency
0.001 0.949 0.050
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.950 0.050
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.950 0.048
E21.4 Other specified disorders of parathyroid gland
0.001 0.950 0.048
E21.2 Other hyperparathyroidism
0.001 0.950 0.048
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.950 0.048
J00 Acute nasopharyngitis [common cold]
0.000 0.951 0.049
E27.8 Other specified disorders of adrenal gland
0.001 0.951 0.047
J37.0 Chronic laryngitis
0.000 0.952 0.048
J70 Respiratory conditions due to other external agents
0.000 0.952 0.048
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.952 0.048
J66 Airway disease due to specific organic dust
0.000 0.952 0.048
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.952 0.048
J62 Pneumoconiosis due to dust containing silica
0.000 0.952 0.048
J65 Pneumoconiosis associated with tuberculosis
0.000 0.952 0.048
J64 Unspecified pneumoconiosis
0.000 0.952 0.048
J60 Coalworker's pneumoconiosis
0.000 0.952 0.048
J02.9 Acute pharyngitis, unspecified
0.000 0.952 0.048
E27.4 Other and unspecified adrenocortical insufficiency
0.001 0.952 0.046
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.953 0.047
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.953 0.047

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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