TreeWAS – Variant ID: rs13213200

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.000	1.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K40 Inguinal hernia	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	0.999	0.001	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
K44 Diaphragmatic hernia	0.000	0.001	0.999
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
K40-K46 Hernia	0.000	0.001	0.998
E16.2 Hypoglycaemia, unspecified	0.998	0.002	0.000
N40 Hyperplasia of prostate	0.000	0.002	0.998
N30-N39 Other diseases of urinary system	0.000	0.002	0.998
N32 Other disorders of bladder	0.000	0.002	0.998
H30-H36 Disorders of choroid and retina	0.997	0.003	0.000
N32.0 Bladder-neck obstruction	0.000	0.003	0.997
N39 Other disorders of urinary system	0.000	0.004	0.996
D50-D53 Nutritional anaemias	0.994	0.006	0.000
N40-N51 Diseases of male genital organs	0.000	0.006	0.994
M35 Other systemic involvement of connective tissue	0.993	0.007	0.000
E20-E35 Disorders of other endocrine glands	0.993	0.007	0.000
D50 Iron deficiency anaemia	0.992	0.008	0.000
M15-M19 Arthrosis	0.992	0.008	0.000
E27 Other disorders of adrenal gland	0.992	0.008	0.000
H25-H28 Disorders of lens	0.990	0.010	0.000
E27.1 Primary adrenocortical insufficiency	0.990	0.010	0.000
E10.3 With ophthalmic complications	0.990	0.010	0.000
E11 Non-insulin-dependent diabetes mellitus	0.990	0.010	0.000
M06 Other rheumatoid arthritis	0.990	0.010	0.000
M17 Gonarthrosis [arthrosis of knee]	0.990	0.010	0.000
M17.9 Gonarthrosis, unspecified	0.986	0.014	0.000
M35.0 Sicca syndrome [Sjogren]	0.986	0.014	0.000
M06.9 Rheumatoid arthritis, unspecified	0.985	0.015	0.000
H26 Other cataract	0.983	0.017	0.000
Chapter XIV Diseases of the genitourinary system	0.000	0.017	0.982
H26.9 Cataract, unspecified	0.981	0.019	0.000
D80-D89 Certain disorders involving the immune mechanism	0.980	0.020	0.000
N39.0 Urinary tract infection, site not specified	0.000	0.020	0.980
Chapter XI Diseases of the digestive system	0.429	0.020	0.551
D50.8 Other iron deficiency anaemias	0.979	0.021	0.000
M23 Internal derangement of knee	0.978	0.022	0.000
N42 Other disorders of prostate	0.000	0.027	0.973
H34 Retinal vascular occlusions	0.969	0.031	0.000
E10.1 With ketoacidosis	0.968	0.032	0.000
K90-K93 Other diseases of the digestive system	0.432	0.033	0.535
D50.9 Iron deficiency anaemia, unspecified	0.967	0.033	0.000
E11.5 With peripheral circulatory complications	0.967	0.033	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.959	0.041	0.000
M31 Other necrotising vasculopathies	0.959	0.041	0.000
E10.2 With renal complications	0.957	0.043	0.000
N39.8 Other specified disorders of urinary system	0.000	0.045	0.955
H35 Other retinal disorders	0.950	0.050	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.949	0.051	0.000
M10 Gout	0.946	0.054	0.000
D86 Sarcoidosis	0.944	0.056	0.000
M24 Other specific joint derangements	0.942	0.058	0.000
H43-H45 Disorders of vitreous body and globe	0.940	0.060	0.000
H35.8 Other specified retinal disorders	0.939	0.061	0.000
N32.8 Other specified disorders of bladder	0.000	0.062	0.938
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.066	0.934
N42.8 Other specified disorders of prostate	0.000	0.073	0.927
M60-M63 Disorders of muscles	0.923	0.077	0.000
M31.6 Other giant cell arteritis	0.922	0.078	0.000
N48 Other disorders of penis	0.000	0.078	0.922
H46-H48 Disorders of optic nerve and visual pathways	0.917	0.083	0.000
D86.9 Sarcoidosis, unspecified	0.914	0.086	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.087	0.913
M34 Systemic sclerosis	0.911	0.089	0.000
E14 Unspecified diabetes mellitus	0.910	0.090	0.000
H53-H54 Visual disturbances and blindness	0.909	0.091	0.000
K90 Intestinal malabsorption	0.848	0.092	0.060
M18 Arthrosis of first carpometacarpal joint	0.907	0.093	0.000
E50-E64 Other nutritional deficiencies	0.905	0.095	0.000
M07 Psoriatic and enteropathic arthropathies	0.900	0.100	0.000
H43 Disorders of vitreous body	0.899	0.101	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.897	0.103	0.000
N34 Urethritis and urethral syndrome	0.000	0.104	0.896
H27 Other disorders of lens	0.896	0.104	0.000
E11.3 With ophthalmic complications	0.895	0.105	0.000
N39.3 Stress incontinence	0.000	0.108	0.892
H36 Retinal disorders in diseases classified elsewhere	0.890	0.110	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.889	0.111	0.000
M23.3 Other meniscus derangements	0.887	0.113	0.000
M24.1 Other articular cartilage disorders	0.884	0.116	0.000
N48.1 Balanoposthitis	0.000	0.116	0.884
H34.8 Other retinal vascular occlusions	0.883	0.117	0.000
H43.1 Vitreous haemorrhage	0.878	0.122	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.873	0.127	0.000
M21 Other acquired deformities of limbs	0.873	0.127	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.868	0.132	0.000
E11.9 Without complications	0.868	0.132	0.000
E10.5 With peripheral circulatory complications	0.867	0.133	0.000
M62 Other disorders of muscle	0.867	0.133	0.000
M22 Disorders of patella	0.867	0.133	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.866	0.134	0.000
H02 Other disorders of eyelid	0.865	0.135	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.136	0.864
N81.2 Incomplete uterovaginal prolapse	0.000	0.138	0.862
H34.2 Other retinal artery occlusions	0.862	0.138	0.000
N81 Female genital prolapse	0.000	0.139	0.861
M11 Other crystal arthropathies	0.860	0.140	0.000
E10.4 With neurological complications	0.860	0.140	0.000
E23 Hypofunction and other disorders of pituitary gland	0.859	0.141	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.000	0.142	0.858
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.857	0.143	0.000
M10.9 Gout, unspecified	0.855	0.145	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.855	0.145	0.000
N48.4 Impotence of organic origin	0.000	0.146	0.854
N32.1 Vesicointestinal fistula	0.000	0.152	0.848
N97 Female infertility	0.000	0.153	0.847
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.845	0.155	0.000
E10.8 With unspecified complications	0.844	0.156	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.842	0.158	0.000
M23.9 Internal derangement of knee, unspecified	0.840	0.160	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.836	0.164	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.164	0.836
H02.6 Xanthelasma of eyelid	0.836	0.164	0.000
N97.9 Female infertility, unspecified	0.000	0.168	0.832
M10.0 Idiopathic gout	0.831	0.169	0.000
M07.3 Other psoriatic arthropathies	0.829	0.170	0.000
H54 Blindness and low vision	0.829	0.171	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.829	0.171	0.000
N36 Other disorders of urethra	0.000	0.173	0.827
M14 Arthropathies in other diseases classified elsewhere	0.823	0.177	0.000
M21.0 Valgus deformity, not elsewhere classified	0.821	0.179	0.000
N85.2 Hypertrophy of uterus	0.000	0.179	0.821
M65-M68 Disorders of synovium and tendon	0.821	0.179	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.820	0.180	0.000
H02.1 Ectropion of eyelid	0.820	0.180	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.819	0.181	0.000
H26.4 After-cataract	0.818	0.182	0.000
D55-D59 Haemolytic anaemias	0.818	0.182	0.000
M34.1 CR(E)ST syndrome	0.817	0.183	0.000
H31 Other disorders of choroid	0.817	0.183	0.000
M23.0 Cystic meniscus	0.815	0.185	0.000
N34.2 Other urethritis	0.000	0.186	0.814
H36.0 Diabetic retinopathy	0.814	0.186	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.812	0.188	0.000
Chapter XX External causes of morbidity and mortality	0.808	0.192	0.000
H27.0 Aphakia	0.808	0.192	0.000
E11.0 With coma	0.803	0.197	0.000
H35.4 Peripheral retinal degeneration	0.802	0.198	0.000
M17.1 Other primary gonarthrosis	0.802	0.198	0.000
H02.5 Other disorders affecting eyelid function	0.802	0.198	0.000
E53 Deficiency of other B group vitamins	0.799	0.201	0.000
E70-E90 Metabolic disorders	0.799	0.201	0.000
M17.0 Primary gonarthrosis, bilateral	0.799	0.201	0.000
E27.2 Addisonian crisis	0.798	0.202	0.000
E10.6 With other specified complications	0.797	0.203	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.797	0.203	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.795	0.205	0.000
M62.8 Other specified disorders of muscle	0.793	0.207	0.000
D84 Other immunodeficiencies	0.792	0.207	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.786	0.214	0.000
E10.0 With coma	0.784	0.216	0.000
N41 Inflammatory diseases of prostate	0.000	0.216	0.784
M22.3 Other derangements of patella	0.782	0.218	0.000
H26.1 Traumatic cataract	0.781	0.219	0.000
E16.1 Other hypoglycaemia	0.780	0.220	0.000
E11.6 With other specified complications	0.780	0.220	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.779	0.221	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.779	0.221	0.000
M00-M03 Infectious arthropathies	0.779	0.221	0.000
N87 Dysplasia of cervix uteri	0.000	0.223	0.777
H30 Chorioretinal inflammation	0.776	0.224	0.000
M35.7 Hypermobility syndrome	0.776	0.224	0.000
Chapter II Neoplasms	0.775	0.225	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.774	0.226	0.000
E13 Other specified diabetes mellitus	0.773	0.227	0.000
H05 Disorders of orbit	0.772	0.228	0.000
D80 Immunodeficiency with predominantly antibody defects	0.772	0.228	0.000
E14.3 With ophthalmic complications	0.772	0.228	0.000
E61 Deficiency of other nutrient elements	0.771	0.229	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.771	0.229	0.000
E83 Disorders of mineral metabolism	0.745	0.230	0.026
N81.9 Female genital prolapse, unspecified	0.000	0.232	0.768
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.766	0.234	0.000
N99-N99 Other disorders of the genitourinary system	0.000	0.234	0.766
M10.94 Gout, unspecified (Hand)	0.765	0.235	0.000
D83 Common variable immunodeficiency	0.765	0.235	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.765	0.235	0.000
D62 Acute posthaemorrhagic anaemia	0.764	0.236	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.764	0.236	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.761	0.239	0.000
M11.2 Other chondrocalcinosis	0.761	0.239	0.000
E20 Hypoparathyroidism	0.760	0.240	0.000
W00-W19 Falls	0.760	0.240	0.000
M15 Polyarthrosis	0.760	0.240	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.758	0.242	0.000
M67 Other disorders of synovium and tendon	0.758	0.242	0.000
M23.1 Discoid meniscus (congenital)	0.757	0.243	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.757	0.243	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.245	0.755
H34.1 Central retinal artery occlusion	0.754	0.245	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.754	0.246	0.000
H34.9 Retinal vascular occlusion, unspecified	0.753	0.247	0.000
M21.1 Varus deformity, not elsewhere classified	0.751	0.248	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.750	0.250	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.749	0.251	0.000
E23.2 Diabetes insipidus	0.749	0.251	0.000
D86.3 Sarcoidosis of skin	0.744	0.256	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.257	0.743
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.743	0.257	0.000
H46 Optic neuritis	0.742	0.258	0.000
E11.1 With ketoacidosis	0.741	0.259	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.741	0.259	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.739	0.261	0.000
C85.1 B-cell lymphoma, unspecified	0.739	0.261	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.736	0.264	0.000
M06.4 Inflammatory polyarthropathy	0.734	0.266	0.000
M86-M90 Other osteopathies	0.734	0.266	0.000
X20-X29 Contact with venomous animals and plants	0.734	0.266	0.000
Q50-Q56 Congenital malformations of genital organs	0.733	0.267	0.000
M62.6 Muscle strain	0.732	0.268	0.000
E14.9 Without complications	0.731	0.269	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.731	0.269	0.000
M17.5 Other secondary gonarthrosis	0.728	0.272	0.000
E14.2 Withrenal complications	0.728	0.272	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.272	0.728
K90.9 Intestinal malabsorption, unspecified	0.703	0.273	0.025
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.273	0.727
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.275	0.725
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.724	0.276	0.000
H43.2 Crystalline deposits in vitreous body	0.724	0.276	0.000
M10.90 Gout, unspecified (Multiple sites)	0.724	0.276	0.000
N32.3 Diverticulum of bladder	0.000	0.278	0.722
N36.2 Urethral caruncle	0.000	0.278	0.722
N97.1 Female infertility of tubal origin	0.000	0.280	0.719
M35.3 Polymyalgia rheumatica	0.719	0.281	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.283	0.717
E10.7 With multiple complications	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.283	0.717
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.283	0.717
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.283	0.000
K44.1 Diaphragmatic hernia with gangrene	0.000	0.284	0.716
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
E53.8 Deficiency of other specified B group vitamins	0.716	0.284	0.000
N37 Urethral disorders in diseases classified elsewhere	0.000	0.284	0.715
N33 Bladder disorders in diseases classified elsewhere	0.000	0.284	0.715
N32.4 Rupture of bladder, nontraumatic	0.000	0.285	0.715
N32.2 Vesical fistula, not elsewhere classified	0.000	0.285	0.715
H32 Chorioretinal disorders in diseases classified elsewhere	0.715	0.285	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.714	0.286	0.000
N39.2 Orthostatic proteinuria, unspecified	0.000	0.286	0.714
M06.98 Rheumatoid arthritis, unspecified (Other)	0.713	0.287	0.000
M67.8 Other specified disorders of synovium and tendon	0.713	0.287	0.000
H54.6 Unqualified visual loss, one eye	0.713	0.287	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.287	0.713
N44 Torsion of testis	0.000	0.287	0.713
M35.9 Systemic involvement of connective tissue, unspecified	0.712	0.288	0.000
M35.8 Other specified systemic involvement of connective tissue	0.712	0.288	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.712	0.288	0.000
M35.5 Multifocal fibrosclerosis	0.712	0.288	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.712	0.288	0.000
M35.2 Behcet's disease	0.712	0.288	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.712	0.288	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.712	0.288	0.000
E32 Diseases of thymus	0.712	0.288	0.000
E31 Polyglandular dysfunction	0.712	0.288	0.000
E30 Disorders of puberty, not elsewhere classified	0.712	0.288	0.000
E25 Adrenogenital disorders	0.712	0.288	0.000
D50.1 Sideropenic dysphagia	0.711	0.289	0.000
E27.5 Adrenomedullary hyperfunction	0.711	0.289	0.000
E27.0 Other adrenocortical overactivity	0.711	0.289	0.000
N81.6 Rectocele	0.000	0.289	0.711
M62.86 Other specified disorders of muscle (Lower leg)	0.710	0.289	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.710	0.290	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.710	0.290	0.000
E11.7 With multiple complications	0.710	0.290	0.000
M06.8 Other specified rheumatoid arthritis	0.709	0.290	0.000
M06.2 Rheumatoid bursitis	0.709	0.290	0.000
M06.1 Adult-onset Still's disease	0.709	0.290	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.709	0.290	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.709	0.290	0.000
V20-V29 Motorcycle rider injured in transport accident	0.709	0.291	0.000
M32 Systemic lupus erythematosus	0.709	0.291	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.709	0.291	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.708	0.292	0.000
M35.1 Other overlap syndromes	0.708	0.292	0.000
W20-W49 Exposure to inanimate mechanical forces	0.708	0.292	0.000
E83.5 Disorders of calcium metabolism	0.706	0.292	0.001
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.707	0.293	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.706	0.294	0.000
H27.1 Dislocation of lens	0.706	0.294	0.000
H26.3 Drug-induced cataract	0.705	0.295	0.000
E23.7 Disorder of pituitary gland, unspecified	0.704	0.296	0.000
D82 Immunodeficiency associated with other major defects	0.703	0.297	0.000
D81 Combined immunodeficiencies	0.703	0.297	0.000
H43.9 Disorder of vitreous body, unspecified	0.702	0.298	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.702	0.298	0.000
H02.0 Entropion and trichiasis of eyelid	0.702	0.298	0.000
M23.5 Chronic instability of knee	0.701	0.299	0.000
M34.8 Other forms of systemic sclerosis	0.701	0.299	0.000
H53 Visual disturbances	0.701	0.299	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.668	0.299	0.033
C02 Malignant neoplasm of other and unspecified parts of tongue	0.701	0.299	0.000
E05.8 Other thyrotoxicosis	0.700	0.300	0.000
C81 Hodgkin's disease	0.700	0.300	0.000
D69 Purpura and other haemorrhagic conditions	0.699	0.301	0.000
M34.9 Systemic sclerosis, unspecified	0.698	0.302	0.000
N42.3 Dysplasia of prostate	0.000	0.302	0.697
M14.6 Neuropathic arthropathy	0.696	0.304	0.000
E40-E46 Malnutrition	0.695	0.305	0.000
H34.0 Transient retinal artery occlusion	0.695	0.305	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.310	0.307	0.384
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.693	0.307	0.000
N81.8 Other female genital prolapse	0.000	0.308	0.692
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.692	0.308	0.000
L20-L30 Dermatitis and eczema	0.691	0.309	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.689	0.311	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.311	0.689
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.688	0.312	0.000
H47.2 Optic atrophy	0.687	0.313	0.000
M31.9 Necrotising vasculopathy, unspecified	0.687	0.313	0.000
M31.8 Other specified necrotising vasculopathies	0.687	0.313	0.000
M31.7 Microscopic polyangiitis	0.687	0.313	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.687	0.313	0.000
M31.2 Lethal midline granuloma	0.687	0.313	0.000
M31.1 Thrombotic microangiopathy	0.687	0.313	0.000
M31.0 Hypersensitivity angiitis	0.687	0.313	0.000
D51 Vitamin B12 deficiency anaemia	0.687	0.313	0.000
N42.0 Calculus of prostate	0.000	0.313	0.687
M06.3 Rheumatoid nodule	0.686	0.314	0.000
H02.3 Blepharochalasis	0.686	0.314	0.000
M24.5 Contracture of joint	0.686	0.314	0.000
D61 Other aplastic anaemias	0.685	0.314	0.000
H47.3 Other disorders of optic disk	0.685	0.315	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.685	0.315	0.000
D86.8 Sarcoidosis of other and combined sites	0.683	0.317	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.317	0.683
W19 Unspecified fall	0.682	0.318	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.682	0.318	0.000
H35.0 Background retinopathy and retinal vascular changes	0.682	0.318	0.000
H35.1 Retinopathy of prematurity	0.681	0.319	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.681	0.319	0.000
K41 Femoral hernia	0.000	0.320	0.680
X23 Contact with hornets, wasps and bees	0.680	0.320	0.000
H54.4 Blindness, one eye	0.679	0.321	0.000
E03.8 Other specified hypothyroidism	0.678	0.322	0.000
M10.4 Other secondary gout	0.678	0.322	0.000
M10.3 Gout due to impairment of renal function	0.678	0.322	0.000
M10.2 Drug-induced gout	0.678	0.322	0.000
M10.1 Lead-induced gout	0.678	0.322	0.000
M24.7 Protrusio acetabuli	0.677	0.323	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.677	0.323	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.675	0.324	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.676	0.324	0.000
M24.9 Joint derangement, unspecified	0.675	0.325	0.000
E61.1 Iron deficiency	0.675	0.325	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.674	0.326	0.000
E24 Cushing's syndrome	0.674	0.326	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.674	0.326	0.000
D53 Other nutritional anaemias	0.674	0.326	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.672	0.328	0.000
M23.4 Loose body in knee	0.672	0.328	0.000
L30 Other dermatitis	0.671	0.329	0.000
N42.2 Atrophy of prostate	0.000	0.330	0.670
W50-W64 Exposure to animate mechanical forces	0.670	0.330	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.670	0.330	0.000
M60 Myositis	0.670	0.330	0.000
N34.3 Urethral syndrome, unspecified	0.000	0.331	0.668
E29 Testicular dysfunction	0.668	0.332	0.000
H53.1 Subjective visual disturbances	0.667	0.333	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.333	0.667
D64.8 Other specified anaemias	0.667	0.333	0.000
E14.1 With ketoacidosis	0.665	0.335	0.000
D86.1 Sarcoidosis of lymph nodes	0.665	0.335	0.000
M91-M94 Chondropathies	0.665	0.335	0.000
H54.0 Blindness, both eyes	0.665	0.335	0.000
M80-M85 Disorders of bone density and structure	0.664	0.335	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.336	0.664
D59 Acquired haemolytic anaemia	0.664	0.336	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.663	0.336	0.000
N41.0 Acute prostatitis	0.000	0.337	0.663
H35.2 Other proliferative retinopathy	0.662	0.338	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.662	0.338	0.000
M61 Calcification and ossification of muscle	0.662	0.338	0.000
N48.3 Priapism	0.000	0.339	0.661
M33 Dermatopolymyositis	0.660	0.340	0.000
M25 Other joint disorders, not elsewhere classified	0.660	0.340	0.000
W07 Fall involving chair	0.660	0.340	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.660	0.340	0.000
K46 Unspecified abdominal hernia	0.000	0.340	0.660
Q43 Other congenital malformations of intestine	0.660	0.340	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.660	0.340	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.659	0.341	0.000
L30.9 Dermatitis, unspecified	0.659	0.341	0.000
D84.9 Immunodeficiency, unspecified	0.658	0.342	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.657	0.342	0.000
H44 Disorders of globe	0.656	0.344	0.000
M86 Osteomyelitis	0.656	0.344	0.000
S40-S49 Injuries to the shoulder and upper arm	0.656	0.344	0.000
K50-K52 Noninfective enteritis and colitis	0.095	0.346	0.559
M34.2 Systemic sclerosis induced by drugs and chemicals	0.653	0.346	0.000
M34.0 Progressive systemic sclerosis	0.653	0.346	0.000
C04 Malignant neoplasm of floor of mouth	0.653	0.347	0.000
E14.8 With unspecified complications	0.652	0.347	0.000
E14.7 With multiple complications	0.652	0.347	0.000
E14.6 With other specified complications	0.652	0.347	0.000
E14.5 With peripheral circulatory complications	0.652	0.347	0.000
E14.4 With neurological complications	0.652	0.347	0.000
E14.0 With coma	0.652	0.347	0.000
H31.0 Chorioretinal scars	0.652	0.348	0.000
K90.3 Pancreatic steatorrhoea	0.608	0.349	0.043
K90.2 Blind loop syndrome, not elsewhere classified	0.608	0.349	0.043
K90.1 Tropical sprue	0.608	0.349	0.043
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.651	0.349	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.651	0.349	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.651	0.349	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.651	0.349	0.000
M24.2 Disorder of ligament	0.651	0.349	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.650	0.350	0.000
N45 Orchitis and epididymitis	0.000	0.350	0.650
E06 Thyroiditis	0.649	0.351	0.000
M22.0 Recurrent dislocation of patella	0.649	0.351	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.649	0.351	0.000
E63 Other nutritional deficiencies	0.649	0.351	0.000
E56 Other vitamin deficiencies	0.649	0.351	0.000
E51 Thiamine deficiency	0.649	0.351	0.000
E50 Vitamin A deficiency	0.649	0.351	0.000
E60 Dietary zinc deficiency	0.649	0.351	0.000
E59 Dietary selenium deficiency	0.649	0.351	0.000
E58 Dietary calcium deficiency	0.649	0.351	0.000
E54 Ascorbic acid deficiency	0.649	0.351	0.000
E52 Niacin deficiency [pellagra]	0.649	0.351	0.000
M13 Other arthritis	0.648	0.352	0.000
N85.6 Intra-uterine synechiae	0.000	0.352	0.648
E80 Disorders of porphyrin and bilirubin metabolism	0.647	0.352	0.000
M07.6 Other enteropathic arthropathies	0.646	0.354	0.000
M07.5 Arthropathy in ulcerative colitis	0.646	0.354	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.646	0.354	0.000
M07.2 Psoriatic spondylitis	0.646	0.354	0.000
M07.1 Arthritis mutilans	0.646	0.354	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.646	0.354	0.000
N48.5 Ulcer of penis	0.000	0.355	0.645
H43.0 Vitreous prolapse	0.645	0.355	0.000
Q00-Q07 Congenital malformations of the nervous system	0.643	0.357	0.000
E83.4 Disorders of magnesium metabolism	0.636	0.357	0.007
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.643	0.357	0.000
N34.1 Nonspecific urethritis	0.000	0.358	0.642
N34.0 Urethral abscess	0.000	0.358	0.642
H27.9 Disorder of lens, unspecified	0.642	0.358	0.000
C07 Malignant neoplasm of parotid gland	0.642	0.358	0.000
H35.3 Degeneration of macula and posterior pole	0.641	0.359	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.641	0.359	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.639	0.361	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.639	0.361	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.638	0.361	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.638	0.362	0.000
M10.96 Gout, unspecified (Lower leg)	0.638	0.362	0.000
M17.3 Other posttraumatic gonarthrosis	0.638	0.362	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.637	0.363	0.000
H54.7 Unspecified visual loss	0.637	0.363	0.000
E84 Cystic fibrosis	0.637	0.363	0.000
C95 Leukaemia of unspecified cell type	0.636	0.363	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations