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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13217162
log Bayes Factor = 19.4226
Chromosome 6   position 27,477,099  (GRCh37) Explore rs13217162 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.518 0.482
E10.9 Without complications
0.000 0.522 0.478
E10.6 With other specified complications
0.000 0.564 0.436
E10.5 With peripheral circulatory complications
0.000 0.567 0.433
E10.4 With neurological complications
0.000 0.573 0.427
E10.3 With ophthalmic complications
0.000 0.590 0.410
E10.1 With ketoacidosis
0.000 0.595 0.405
E10.8 With unspecified complications
0.000 0.610 0.390
E10.2 With renal complications
0.000 0.654 0.346
E10.7 With multiple complications
0.000 0.654 0.345
E10.0 With coma
0.000 0.655 0.345
E10-E14 Diabetes mellitus
0.000 0.678 0.322
E13 Other specified diabetes mellitus
0.000 0.728 0.271
E83 Disorders of mineral metabolism
0.000 0.729 0.271
E13.9 Without complications
0.000 0.765 0.235
K90 Intestinal malabsorption
0.000 0.766 0.234
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.769 0.231
E12 Malnutrition-related diabetes mellitus
0.000 0.769 0.231
E70-E90 Metabolic disorders
0.000 0.771 0.229
E88 Other metabolic disorders
0.000 0.780 0.220
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.785 0.215
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.795 0.205
E16 Other disorders of pancreatic internal secretion
0.000 0.796 0.204
E16.2 Hypoglycaemia, unspecified
0.000 0.802 0.198
E13.3 With ophthalmic complications
0.000 0.804 0.196
E13.8 With unspecified complications
0.000 0.805 0.195
E13.7 With multiple complications
0.000 0.805 0.195
E13.6 With other specified complications
0.000 0.805 0.195
E13.5 With peripheral circulatory complications
0.000 0.805 0.195
E13.4 With neurological complications
0.000 0.805 0.195
E13.2 With renal complications
0.000 0.805 0.195
E13.1 With ketoacidosis
0.000 0.805 0.195
E13.0 With coma
0.000 0.805 0.195
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.806 0.194
E83.8 Other disorders of mineral metabolism
0.000 0.806 0.194
E83.2 Disorders of zinc metabolism
0.000 0.806 0.194
E83.0 Disorders of copper metabolism
0.000 0.806 0.194
E40-E46 Malnutrition
0.000 0.809 0.190
E11 Non-insulin-dependent diabetes mellitus
0.000 0.813 0.187
E14 Unspecified diabetes mellitus
0.000 0.819 0.181
E85 Amyloidosis
0.000 0.824 0.176
E88.8 Other specified metabolic disorders
0.000 0.825 0.174
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.826 0.174
E88.2 Lipomatosis, not elsewhere classified
0.000 0.828 0.172
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.828 0.172
E14.3 With ophthalmic complications
0.000 0.832 0.168
K90.3 Pancreatic steatorrhoea
0.000 0.832 0.168
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.832 0.168
K90.1 Tropical sprue
0.000 0.832 0.168
E12.9 Without complications
0.000 0.834 0.166
E12.8 With unspecified complications
0.000 0.834 0.166
E12.7 With multiple complications
0.000 0.834 0.166
E12.6 With other specified complications
0.000 0.834 0.166
E12.5 With peripheral circulatory complications
0.000 0.834 0.166
E12.4 With neurological complications
0.000 0.834 0.166
E12.3 With ophthalmic complications
0.000 0.834 0.166
E12.2 With renal complications
0.000 0.834 0.166
E12.1 With ketoacidosis
0.000 0.834 0.166
E12.0 With coma
0.000 0.834 0.166
E88.3 Tumour lysis syndrome
0.000 0.834 0.165
E84 Cystic fibrosis
0.000 0.836 0.164
E77 Disorders of glycoprotein metabolism
0.000 0.836 0.164
E76 Disorders of glycosaminoglycan metabolism
0.000 0.836 0.164
E72 Other disorders of amino-acid metabolism
0.000 0.836 0.164
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.836 0.164
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.836 0.164
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.837 0.162
E46 Unspecified protein-energy malnutrition
0.000 0.839 0.161
K90.8 Other intestinal malabsorption
0.000 0.840 0.159
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.842 0.158
E11.2 With renal complications
0.000 0.842 0.158
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.843 0.157
E15 Nondiabetic hypoglycaemic coma
0.000 0.845 0.154
E70 Disorders of aromatic amino-acid metabolism
0.000 0.847 0.153
E11.0 With coma
0.000 0.849 0.151
E88.9 Metabolic disorder, unspecified
0.000 0.853 0.147
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.854 0.146
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.854 0.146
E16.4 Abnormal secretion of gastrin
0.000 0.854 0.146
E16.3 Increased secretion of glucagon
0.000 0.854 0.146
E11.4 With neurological complications
0.000 0.854 0.146
E11.1 With ketoacidosis
0.000 0.854 0.146
E79 Disorders of purine and pyrimidine metabolism
0.000 0.854 0.146
E85.9 Amyloidosis, unspecified
0.000 0.858 0.142
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.863 0.137
E45 Retarded development following protein-energy malnutrition
0.000 0.863 0.137
E43 Unspecified severe protein-energy malnutrition
0.000 0.863 0.137
E42 Marasmic kwashiorkor
0.000 0.863 0.137
E41 Nutritional marasmus
0.000 0.863 0.137
E40 Kwashiorkor
0.000 0.863 0.137
E14.5 With peripheral circulatory complications
0.000 0.864 0.136
E11.7 With multiple complications
0.000 0.866 0.134
E11.8 With unspecified complications
0.000 0.867 0.133
E11.5 With peripheral circulatory complications
0.000 0.869 0.130
E14.7 With multiple complications
0.000 0.870 0.130
E14.2 Withrenal complications
0.000 0.870 0.130
E14.0 With coma
0.000 0.870 0.130
E85.4 Organ-limited amyloidosis
0.000 0.872 0.128
E85.8 Other amyloidosis
0.000 0.873 0.127
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.873 0.127
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.873 0.127
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.873 0.127
E83.3 Disorders of phosphorus metabolism
0.000 0.874 0.126
E65-E68 Obesity and other hyperalimentation
0.000 0.874 0.126
E73 Lactose intolerance
0.000 0.875 0.125
E14.6 With other specified complications
0.000 0.876 0.123
E11.6 With other specified complications
0.000 0.878 0.122
E85.3 Secondary systemic amyloidosis
0.000 0.879 0.120
E74 Other disorders of carbohydrate metabolism
0.000 0.881 0.119
E14.4 With neurological complications
0.000 0.881 0.119
E71.3 Disorders of fatty-acid metabolism
0.000 0.882 0.118
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.882 0.118
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.882 0.118
E71.0 Maple-syrup-urine disease
0.000 0.882 0.118
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.882 0.118
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.882 0.118
E72.5 Disorders of glycine metabolism
0.000 0.882 0.118
E72.4 Disorders of ornithine metabolism
0.000 0.882 0.118
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.882 0.118
E72.2 Disorders of urea cycle metabolism
0.000 0.882 0.118
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.882 0.118
E72.0 Disorders of amino-acid transport
0.000 0.882 0.118
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.882 0.118
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.882 0.118
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.882 0.118
E76.2 Other mucopolysaccharidoses
0.000 0.882 0.118
E76.1 Mucopolysaccharidosis, type II
0.000 0.882 0.118
E76.0 Mucopolysaccharidosis, type I
0.000 0.882 0.118
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.882 0.118
E77.8 Other disorders of glycoprotein metabolism
0.000 0.882 0.118
E77.1 Defects in glycoprotein degradation
0.000 0.882 0.118
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.882 0.118
E84.9 Cystic fibrosis, unspecified
0.000 0.882 0.118
E84.8 Cystic fibrosis with other manifestations
0.000 0.882 0.118
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.882 0.118
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.882 0.118
E14.1 With ketoacidosis
0.000 0.882 0.118
E80.4 Gilbert's syndrome
0.000 0.884 0.116
E75.6 Lipid storage disorder, unspecified
0.000 0.886 0.113
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.886 0.113
E75.3 Sphingolipidosis, unspecified
0.000 0.886 0.113
E75.2 Other sphingolipidosis
0.000 0.886 0.113
E75.1 Other gangliosidosis
0.000 0.886 0.113
E75.0 GM2 gangliosidosis
0.000 0.886 0.113
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.887 0.113
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.887 0.112
E80.5 Crigler-Najjar syndrome
0.000 0.887 0.112
E80.3 Defects of catalase and peroxydase
0.000 0.887 0.112
E80.1 Porphyria cutanea tarda
0.000 0.887 0.112
E80.0 Hereditary erythropoietic porphyria
0.000 0.887 0.112
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.890 0.110
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.890 0.110
E70.2 Disorders of tyrosine metabolism
0.000 0.890 0.110
E70.1 Other hyperphenylalaninaemias
0.000 0.890 0.110
E70.0 Classical phenylketonuria
0.000 0.890 0.110
E80.6 Other disorders of bilirubin metabolism
0.000 0.891 0.109
E75.5 Other lipid storage disorders
0.000 0.892 0.107
E16.1 Other hypoglycaemia
0.000 0.894 0.106
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.895 0.104
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.895 0.104
E79.1 Lesch-Nyhan syndrome
0.000 0.895 0.104
E80.2 Other porphyria
0.000 0.896 0.104
E65 Localised adiposity
0.000 0.900 0.100
E70.3 Albinism
0.000 0.901 0.099
E83.4 Disorders of magnesium metabolism
0.000 0.901 0.099
E44.1 Mild protein-energy malnutrition
0.000 0.902 0.098
E44.0 Moderate protein-energy malnutrition
0.000 0.902 0.098
E11.3 With ophthalmic complications
0.000 0.903 0.097
E14.8 With unspecified complications
0.000 0.906 0.093
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.907 0.093
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.908 0.092
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.909 0.091
E67 Other hyperalimentation
0.000 0.909 0.090
E68 Sequelae of hyperalimentation
0.000 0.909 0.090
E73.8 Other lactose intolerance
0.000 0.910 0.090
E73.1 Secondary lactase deficiency
0.000 0.910 0.090
E73.0 Congenital lactase deficiency
0.000 0.910 0.090
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.914 0.086
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.914 0.085
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.914 0.085
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.914 0.085
E74.2 Disorders of galactose metabolism
0.000 0.914 0.085
E74.1 Disorders of fructose metabolism
0.000 0.914 0.085
E89.4 Postprocedural ovarian failure
0.000 0.915 0.085
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.916 0.084
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.918 0.081
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.918 0.081
E89.5 Postprocedural testicular hypofunction
0.000 0.918 0.081
E89.1 Postprocedural hypoinsulinaemia
0.000 0.918 0.081
E50-E64 Other nutritional deficiencies
0.000 0.919 0.081
E89.2 Postprocedural hypoparathyroidism
0.000 0.919 0.081
E87.0 Hyperosmolality and hypernatraemia
0.000 0.920 0.080
E00-E07 Disorders of thyroid gland
0.000 0.920 0.080
E87.5 Hyperkalaemia
0.000 0.922 0.078
E74.0 Glycogen storage disease
0.000 0.923 0.077
K90.9 Intestinal malabsorption, unspecified
0.000 0.924 0.076
E87.3 Alkalosis
0.000 0.925 0.074
E78.2 Mixed hyperlipidaemia
0.000 0.929 0.071
E78.4 Other hyperlipidaemia
0.000 0.932 0.068
E89.0 Postprocedural hypothyroidism
0.000 0.932 0.068
E87.7 Fluid overload
0.000 0.932 0.068
E78.1 Pure hyperglyceridaemia
0.000 0.932 0.068
E78.3 Hyperchylomicronaemia
0.000 0.933 0.067
E87.4 Mixed disorder of acid-base balance
0.000 0.934 0.066
E67.8 Other specified hyperalimentation
0.000 0.935 0.065
E67.3 Hypervitaminosis D
0.000 0.935 0.065
E67.2 Megavitamin-B6 syndrome
0.000 0.935 0.065
E67.1 Hypercarotenaemia
0.000 0.935 0.065
E67.0 Hypervitaminosis A
0.000 0.935 0.065
E78.6 Lipoprotein deficiency
0.000 0.936 0.064
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.942 0.058
E63 Other nutritional deficiencies
0.000 0.942 0.058
E50 Vitamin A deficiency
0.000 0.942 0.058
E60 Dietary zinc deficiency
0.000 0.942 0.058
E59 Dietary selenium deficiency
0.000 0.942 0.058
E54 Ascorbic acid deficiency
0.000 0.942 0.058
E52 Niacin deficiency [pellagra]
0.000 0.942 0.058
E58 Dietary calcium deficiency
0.000 0.942 0.057
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.943 0.057
E00 Congenital iodine-deficiency syndrome
0.000 0.943 0.057
E06 Thyroiditis
0.000 0.943 0.057
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.943 0.056
E04 Other non-toxic goitre
0.000 0.944 0.056
E56 Other vitamin deficiencies
0.000 0.944 0.056
E07 Other disorders of thyroid
0.000 0.944 0.056
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.944 0.056
E51 Thiamine deficiency
0.000 0.945 0.055
E53 Deficiency of other B group vitamins
0.000 0.946 0.054
E04.9 Non-toxic goitre, unspecified
0.000 0.949 0.051
E73.9 Lactose intolerance, unspecified
0.001 0.949 0.050
E55 Vitamin D deficiency
0.000 0.951 0.048
R31 Unspecified haematuria
0.047 0.953 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.953 0.047
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.954 0.046
E87.2 Acidosis
0.000 0.955 0.045
E83.5 Disorders of calcium metabolism
0.000 0.955 0.044
E20-E35 Disorders of other endocrine glands
0.000 0.956 0.044
E04.0 Non-toxic diffuse goitre
0.000 0.957 0.042
E89.3 Postprocedural hypopituitarism
0.000 0.958 0.042
E50.9 Vitamin A deficiency, unspecified
0.000 0.958 0.042
E50.8 Other manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.958 0.042
E50.5 Vitamin A deficiency with night blindness
0.000 0.958 0.042
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.958 0.042
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.958 0.042
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.958 0.042
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.958 0.042
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.958 0.042
E63.9 Nutritional deficiency, unspecified
0.000 0.958 0.042
E63.8 Other specified nutritional deficiencies
0.000 0.958 0.042
E63.1 Imbalance of constituents of food intake
0.000 0.958 0.042
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.958 0.042
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.958 0.042
E64.8 Sequelae of other nutritional deficiencies
0.000 0.958 0.042
E64.3 Sequelae of rickets
0.000 0.958 0.042
E64.2 Sequelae of vitamin C deficiency
0.000 0.958 0.042
E64.1 Sequelae of vitamin A deficiency
0.000 0.958 0.042
E64.0 Sequelae of protein-energy malnutrition
0.000 0.958 0.042
E53.9 Vitamin B deficiency, unspecified
0.000 0.958 0.042
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.958 0.041
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.958 0.041
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.958 0.041
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.958 0.041
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.958 0.041
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.958 0.041
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.958 0.041
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.958 0.041
E06.3 Autoimmune thyroiditis
0.000 0.959 0.041
E06.5 Other chronic thyroiditis
0.000 0.959 0.041
E06.4 Drug-induced thyroiditis
0.000 0.959 0.041
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.959 0.041
E06.1 Subacute thyroiditis
0.000 0.959 0.041
E06.0 Acute thyroiditis
0.000 0.959 0.041
E04.8 Other specified non-toxic goitre
0.000 0.959 0.041
E06.9 Thyroiditis, unspecified
0.000 0.959 0.041
E07.9 Disorder of thyroid, unspecified
0.000 0.959 0.041
E56.9 Vitamin deficiency, unspecified
0.000 0.960 0.040
E56.8 Deficiency of other vitamins
0.000 0.960 0.040
E56.0 Deficiency of vitamin E
0.000 0.960 0.040
E07.1 Dyshormogenetic goitre
0.000 0.960 0.040
E07.0 Hypersecretion of calcitonin
0.000 0.960 0.040
E51.9 Thiamine deficiency, unspecified
0.000 0.960 0.040
E51.8 Other manifestations of thiamine deficiency
0.000 0.960 0.040
E51.1 Beriberi
0.000 0.960 0.040
E53.1 Pyridoxine deficiency
0.000 0.961 0.039
E53.0 Riboflavin deficiency
0.000 0.961 0.039
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.961 0.039
E56.1 Deficiency of vitamin K
0.000 0.962 0.038
E07.8 Other specified disorders of thyroid
0.000 0.962 0.038
E51.2 Wernicke's encephalopathy
0.000 0.963 0.037
E86 Volume depletion
0.000 0.964 0.036
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.964 0.036
E03 Other hypothyroidism
0.000 0.964 0.036
E05.8 Other thyrotoxicosis
0.000 0.964 0.035
E27.1 Primary adrenocortical insufficiency
0.000 0.965 0.035
E55.0 Rickets, active
0.000 0.965 0.035
E20 Hypoparathyroidism
0.000 0.966 0.034
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.966 0.034
E27 Other disorders of adrenal gland
0.000 0.966 0.034
E14.9 Without complications
0.000 0.967 0.033
E05.5 Thyroid crisis or storm
0.000 0.967 0.033
E05.4 Thyrotoxicosis factitia
0.000 0.967 0.033
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.967 0.033
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.967 0.033
E26 Hyperaldosteronism
0.000 0.967 0.033
E29 Testicular dysfunction
0.000 0.968 0.032
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.968 0.031
E32 Diseases of thymus
0.000 0.968 0.031
E31 Polyglandular dysfunction
0.000 0.968 0.031
E30 Disorders of puberty, not elsewhere classified
0.000 0.968 0.031
E25 Adrenogenital disorders
0.000 0.968 0.031
E53.8 Deficiency of other specified B group vitamins
0.000 0.970 0.030
E61 Deficiency of other nutrient elements
0.001 0.970 0.030
E78.8 Other disorders of lipoprotein metabolism
0.001 0.970 0.029
E24 Cushing's syndrome
0.000 0.970 0.030
M25.57 Pain in joint (Ankle and foot)
0.000 0.971 0.029
E34 Other endocrine disorders
0.000 0.972 0.028
E04.1 Non-toxic single thyroid nodule
0.000 0.972 0.028
E20.9 Hypoparathyroidism, unspecified
0.000 0.972 0.028
E03.8 Other specified hypothyroidism
0.000 0.972 0.028
E04.2 Non-toxic multinodular goitre
0.000 0.973 0.027
M25.5 Pain in joint
0.000 0.973 0.027
E03.5 Myxoedema coma
0.000 0.974 0.026
E03.4 Atrophy of thyroid (acquired)
0.000 0.974 0.026
E03.3 Postinfectious hypothyroidism
0.000 0.974 0.026
E03.1 Congenital hypothyroidism without goitre
0.000 0.974 0.026
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.974 0.026
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.974 0.026
E26.0 Primary hyperaldosteronism
0.000 0.974 0.026
E55.9 Vitamin D deficiency, unspecified
0.000 0.975 0.025
E28 Ovarian dysfunction
0.000 0.975 0.025
E23 Hypofunction and other disorders of pituitary gland
0.000 0.975 0.025
E24.2 Drug-induced Cushing's syndrome
0.000 0.975 0.025
E20.8 Other hypoparathyroidism
0.000 0.975 0.025
E20.1 Pseudohypoparathyroidism
0.000 0.975 0.025
E20.0 Idiopathic hypoparathyroidism
0.000 0.975 0.025
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.975 0.025
E27.5 Adrenomedullary hyperfunction
0.000 0.975 0.024
E27.0 Other adrenocortical overactivity
0.000 0.975 0.024
E26.9 Hyperaldosteronism, unspecified
0.000 0.976 0.024
E26.8 Other hyperaldosteronism
0.000 0.976 0.024
E26.1 Secondary hyperaldosteronism
0.000 0.976 0.024
M25.51 Pain in joint (Shoulder region)
0.000 0.976 0.024
E29.1 Testicular hypofunction
0.000 0.976 0.024
E29.9 Testicular dysfunction, unspecified
0.000 0.977 0.023
E29.8 Other testicular dysfunction
0.000 0.977 0.023
E29.0 Testicular hyperfunction
0.000 0.977 0.023
E25.9 Adrenogenital disorder, unspecified
0.000 0.977 0.023
E25.8 Other adrenogenital disorders
0.000 0.977 0.023
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.977 0.023
E30.9 Disorder of puberty, unspecified
0.000 0.977 0.023
E30.8 Other disorders of puberty
0.000 0.977 0.023
E30.1 Precocious puberty
0.000 0.977 0.023
E30.0 Delayed puberty
0.000 0.977 0.023
E31.9 Polyglandular dysfunction, unspecified
0.000 0.977 0.023
E31.8 Other polyglandular dysfunction
0.000 0.977 0.023
E31.1 Polyglandular hyperfunction
0.000 0.977 0.023
E31.0 Autoimmune polyglandular failure
0.000 0.977 0.023
E32.9 Disease of thymus, unspecified
0.000 0.977 0.023
E32.8 Other diseases of thymus
0.000 0.977 0.023
E32.1 Abscess of thymus
0.000 0.977 0.023
E32.0 Persistent hyperplasia of thymus
0.000 0.977 0.023
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.977 0.023
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.977 0.023
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.977 0.023
E23.2 Diabetes insipidus
0.000 0.978 0.022
M25.58 Pain in joint (Other)
0.000 0.978 0.022
E61.9 Deficiency of nutrient element, unspecified
0.001 0.978 0.021
E61.8 Deficiency of other specified nutrient elements
0.001 0.978 0.021
E61.7 Deficiency of multiple nutrient elements
0.001 0.978 0.021
E61.6 Vanadium deficiency
0.001 0.978 0.021
E61.5 Molybdenum deficiency
0.001 0.978 0.021
E61.4 Chromium deficiency
0.001 0.978 0.021
E61.3 Manganese deficiency
0.001 0.978 0.021
E61.0 Copper deficiency
0.001 0.978 0.021
M25.52 Pain in joint (Upper arm)
0.000 0.978 0.022
E66 Obesity
0.000 0.978 0.022
E24.8 Other Cushing's syndrome
0.000 0.978 0.021
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.978 0.021
E24.3 Ectopic ACTH syndrome
0.000 0.978 0.021
E24.1 Nelson's syndrome
0.000 0.978 0.021
E34.5 Androgen resistance syndrome
0.000 0.980 0.020
E34.4 Constitutional tall stature
0.000 0.980 0.020
E34.3 Short stature, not elsewhere classified
0.000 0.980 0.020
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.980 0.020
E34.1 Other hypersecretion of intestinal hormones
0.000 0.980 0.020
E27.2 Addisonian crisis
0.000 0.980 0.020
E34.0 Carcinoid syndrome
0.000 0.980 0.020
E24.0 Pituitary-dependent Cushing's disease
0.000 0.980 0.019
E87.6 Hypokalaemia
0.000 0.981 0.019
E34.8 Other specified endocrine disorders
0.000 0.981 0.019
E34.9 Endocrine disorder, unspecified
0.000 0.981 0.019
E28.2 Polycystic ovarian syndrome
0.000 0.981 0.019
M25.54 Pain in joint (Hand)
0.000 0.981 0.019
E28.9 Ovarian dysfunction, unspecified
0.000 0.982 0.018
E28.8 Other ovarian dysfunction
0.000 0.982 0.018
E28.1 Androgen excess
0.000 0.982 0.018
E28.0 Oestrogen excess
0.000 0.982 0.018
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.982 0.018
E23.1 Drug-induced hypopituitarism
0.000 0.982 0.018
M25.53 Pain in joint (Forearm)
0.000 0.982 0.018
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.982 0.018
E23.7 Disorder of pituitary gland, unspecified
0.000 0.982 0.017
E61.2 Magnesium deficiency
0.001 0.983 0.016
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.984 0.016
E27.8 Other specified disorders of adrenal gland
0.000 0.984 0.016
G31.8 Other specified degenerative diseases of nervous system
0.000 0.984 0.016
E66.1 Drug-induced obesity
0.000 0.984 0.016
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.984 0.016
K90-K93 Other diseases of the digestive system
0.000 0.984 0.015
E24.9 Cushing's syndrome, unspecified
0.000 0.985 0.015
E23.6 Other disorders of pituitary gland
0.000 0.985 0.015
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.986 0.014
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.986 0.014
G31.0 Circumscribed brain atrophy
0.000 0.986 0.014
E66.0 Obesity due to excess calories
0.000 0.986 0.014
G30 Alzheimer's disease
0.000 0.986 0.014
M25.59 Pain in joint (Site unspecified)
0.000 0.987 0.013
G30-G32 Other degenerative diseases of the nervous system
0.000 0.987 0.013
G30.9 Alzheimer's disease, unspecified
0.000 0.987 0.013
G30.0 Alzheimer's disease with early onset
0.000 0.988 0.012
E27.9 Disorder of adrenal gland, unspecified
0.001 0.988 0.012
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.989 0.011
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.989 0.011
G44.2 Tension-type headache
0.011 0.989 0.000
E28.3 Primary ovarian failure
0.001 0.989 0.011
E22 Hyperfunction of pituitary gland
0.000 0.989 0.011
G30.8 Other Alzheimer's disease
0.000 0.989 0.011
E21.4 Other specified disorders of parathyroid gland
0.000 0.989 0.010
E21.2 Other hyperparathyroidism
0.000 0.989 0.010
G30.1 Alzheimer's disease with late onset
0.000 0.990 0.010
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.991 0.009
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.991 0.009
E21.3 Hyperparathyroidism, unspecified
0.000 0.991 0.009
G31.2 Degeneration of nervous system due to alcohol
0.000 0.991 0.008
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.992 0.008
K93.1 Megacolon in Chagas' disease
0.000 0.992 0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.992 0.008
E22.8 Other hyperfunction of pituitary gland
0.000 0.992 0.008
E61.1 Iron deficiency
0.001 0.992 0.007
E21.0 Primary hyperparathyroidism
0.000 0.992 0.008
M25.50 Pain in joint (Multiple sites)
0.000 0.992 0.008
E11.9 Without complications
0.000 0.992 0.008
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.993 0.007
E23.0 Hypopituitarism
0.000 0.993 0.007
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.993 0.007
K02.9 Dental caries, unspecified
0.000 0.993 0.007
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.993 0.007
E22.1 Hyperprolactinaemia
0.000 0.993 0.007
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.993 0.007
G44 Other headache syndromes
0.006 0.994 0.000
K02.8 Other dental caries
0.000 0.994 0.006
K22.8 Other specified diseases of oesophagus
0.006 0.994 0.000
K02 Dental caries
0.000 0.994 0.006
G44.8 Other specified headache syndromes
0.006 0.994 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.995 0.005
N60.1 Diffuse cystic mastopathy
0.000 0.995 0.005
E05.9 Thyrotoxicosis, unspecified
0.000 0.995 0.005
G44.0 Cluster headache syndrome
0.005 0.995 0.000
K02.1 Caries of dentin
0.000 0.995 0.005
E22.0 Acromegaly and pituitary gigantism
0.001 0.995 0.004
G44.1 Vascular headache, not elsewhere classified
0.005 0.995 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.005 0.995 0.000
G82.5 Tetraplegia, unspecified
0.000 0.995 0.005
G44.3 Chronic posttraumatic headache
0.004 0.996 0.000
K02.5 Caries with pulp exposure
0.000 0.996 0.004
K02.4 Odontoclasia
0.000 0.996 0.004
K02.3 Arrested dental caries
0.000 0.996 0.004
K02.2 Caries of cementum
0.000 0.996 0.004
K02.0 Caries limited to enamel
0.000 0.996 0.004
G82.4 Spastic tetraplegia
0.000 0.996 0.004
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.996 0.004
Z34.9 Supervision of normal pregnancy, unspecified
0.004 0.996 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.996 0.004
G82 Paraplegia and tetraplegia
0.000 0.996 0.004
G82.1 Spastic paraplegia
0.000 0.996 0.004
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.004 0.996 0.000
M41.9 Scoliosis, unspecified
0.004 0.996 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.996 0.004
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.996 0.004
G54.9 Nerve root and plexus disorder, unspecified
0.004 0.996 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
E66.9 Obesity, unspecified
0.000 0.996 0.004
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.996 0.004
M94.86 Other specified disorders of cartilage (Lower leg)
0.003 0.997 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.997 0.003
C71.2 Temporal lobe
0.003 0.997 0.000
G82.3 Flaccid tetraplegia
0.000 0.997 0.003
G82.0 Flaccid paraplegia
0.000 0.997 0.003
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.003 0.997 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.003 0.997 0.000
N04.9 Unspecified
0.000 0.997 0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.000 0.997 0.003
G71.1 Myotonic disorders
0.000 0.997 0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.003 0.997 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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