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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13218331
log Bayes Factor = 136.275
Chromosome 6   position 32,411,362  (GRCh37) Explore rs13218331 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
1.000 0.000 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.998 0.002 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.998 0.002 0.000
C44.7 Skin of lower limb, including hip
0.998 0.002 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.000 0.002 0.998
M07.39 Other psoriatic arthropathies (Site unspecified)
0.997 0.003 0.000
D86 Sarcoidosis
0.000 0.004 0.996
D86.9 Sarcoidosis, unspecified
0.000 0.004 0.996
M07.30 Other psoriatic arthropathies (Multiple sites)
0.995 0.005 0.000
C44.2 Skin of ear and external auricular canal
0.994 0.006 0.000
Chapter II Neoplasms
0.994 0.006 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.990 0.010 0.000
M06.0 Seronegative rheumatoid arthritis
0.990 0.010 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.989 0.011 0.000
D50-D53 Nutritional anaemias
0.000 0.011 0.989
C44.4 Skin of scalp and neck
0.989 0.011 0.000
C44.5 Skin of trunk
0.988 0.012 0.000
K51.4 Pseudopolyposis of colon
0.988 0.012 0.000
D50.9 Iron deficiency anaemia, unspecified
0.000 0.013 0.987
D50 Iron deficiency anaemia
0.000 0.014 0.986
C83.3 Large cell (diffuse)
0.985 0.015 0.000
C73 Malignant neoplasm of thyroid gland
0.985 0.015 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.016 0.984
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.018 0.981
D86.0 Sarcoidosis of lung
0.000 0.019 0.981
D51 Vitamin B12 deficiency anaemia
0.000 0.021 0.979
E10.1 With ketoacidosis
0.000 0.021 0.979
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.977 0.023 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.028 0.972
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.971 0.029 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.044 0.956
K50.9 Crohn's disease, unspecified
0.955 0.045 0.000
C82.0 Small cleaved cell, follicular
0.954 0.046 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.048 0.952
K90 Intestinal malabsorption
0.000 0.056 0.943
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.943 0.057 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.937 0.063 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.929 0.071 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.074 0.926
C43 Malignant melanoma of skin
0.914 0.086 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.911 0.089 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.907 0.093 0.000
M06.3 Rheumatoid nodule
0.906 0.094 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.098 0.902
Z93.2 Ileostomy status
0.900 0.100 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.899 0.101 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.103 0.897
M05 Seropositive rheumatoid arthritis
0.897 0.103 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.106 0.894
K51.2 Ulcerative (chronic) proctitis
0.879 0.121 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.872 0.128 0.000
E27 Other disorders of adrenal gland
0.000 0.129 0.871
D52 Folate deficiency anaemia
0.000 0.136 0.864
M07.34 Other psoriatic arthropathies (Hand)
0.864 0.136 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.862 0.138 0.000
K50.8 Other Crohn's disease
0.861 0.139 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.142 0.858
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.858 0.142 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.856 0.144 0.000
C74 Malignant neoplasm of adrenal gland
0.856 0.144 0.000
E10.4 With neurological complications
0.000 0.145 0.855
C06 Malignant neoplasm of other and unspecified parts of mouth
0.854 0.146 0.000
C02.9 Tongue, unspecified
0.849 0.151 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.152 0.848
D86.8 Sarcoidosis of other and combined sites
0.000 0.161 0.839
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.161 0.839
E14 Unspecified diabetes mellitus
0.000 0.164 0.836
L40-L45 Papulosquamous disorders
0.821 0.167 0.012
C82.2 Large cell, follicular
0.831 0.169 0.000
K51.8 Other ulcerative colitis
0.828 0.172 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.825 0.175 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.824 0.176 0.000
C82.3 Follicular lymphoma grade IIIa
0.817 0.183 0.000
K51.5 Mucosal proctocolitis
0.812 0.188 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.812 0.188 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.189 0.811
E07 Other disorders of thyroid
0.000 0.200 0.800
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.201 0.799
E10.0 With coma
0.000 0.205 0.795
M06.37 Rheumatoid nodule (Ankle and foot)
0.795 0.205 0.000
E10.8 With unspecified complications
0.000 0.206 0.794
C44.0 Skin of lip
0.792 0.208 0.000
J45 Asthma
0.000 0.210 0.790
C02.2 Ventral surface of tongue
0.789 0.211 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.789 0.211 0.000
E10.5 With peripheral circulatory complications
0.000 0.213 0.787
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.786 0.214 0.000
C02.1 Border of tongue
0.775 0.225 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.225 0.775
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.772 0.228 0.000
E22 Hyperfunction of pituitary gland
0.000 0.234 0.766
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.237 0.763
E05.8 Other thyrotoxicosis
0.000 0.238 0.762
E10.2 With renal complications
0.000 0.240 0.760
C03 Malignant neoplasm of gum
0.754 0.245 0.000
L40.3 Pustulosis palmaris et plantaris
0.753 0.247 0.000
C05 Malignant neoplasm of palate
0.749 0.251 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.748 0.251 0.000
C09 Malignant neoplasm of tonsil
0.748 0.252 0.000
M11 Other crystal arthropathies
0.747 0.253 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.746 0.254 0.000
C06.0 Cheek mucosa
0.745 0.255 0.000
E03.8 Other specified hypothyroidism
0.000 0.255 0.745
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.258 0.742
L40.1 Generalised pustular psoriasis
0.741 0.259 0.000
C12 Malignant neoplasm of pyriform sinus
0.735 0.265 0.000
M12 Other specific arthropathies
0.735 0.265 0.000
C13 Malignant neoplasm of hypopharynx
0.735 0.265 0.000
M14 Arthropathies in other diseases classified elsewhere
0.734 0.265 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.733 0.267 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.731 0.269 0.000
E20 Hypoparathyroidism
0.000 0.271 0.729
K90.8 Other intestinal malabsorption
0.000 0.272 0.728
C10 Malignant neoplasm of oropharynx
0.728 0.272 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.727 0.273 0.000
J45.0 Predominantly allergic asthma
0.000 0.274 0.726
L43 Lichen planus
0.718 0.277 0.005
E14.3 With ophthalmic complications
0.000 0.277 0.723
C02.4 Lingual tonsil
0.720 0.280 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.719 0.281 0.000
E10.6 With other specified complications
0.000 0.282 0.718
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
C82.6 Cutaneous follicle centre lymphoma
0.717 0.283 0.000
C82.5 Diffuse follicle centre lymphoma
0.717 0.283 0.000
C82.4 Follicular lymphoma grade IIIb
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.717 0.283 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C93 Monocytic leukaemia
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.717 0.283 0.000
M07.5 Arthropathy in ulcerative colitis
0.717 0.283 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.717 0.283 0.000
M07.2 Psoriatic spondylitis
0.717 0.283 0.000
M07.1 Arthritis mutilans
0.717 0.283 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.716 0.284 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.285 0.714
E29 Testicular dysfunction
0.000 0.288 0.712
L42 Pityriasis rosea
0.705 0.290 0.006
C74.9 Adrenal gland, unspecified
0.710 0.290 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.710 0.290 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.710 0.290 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.710 0.290 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.710 0.290 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.710 0.290 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.710 0.290 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.710 0.290 0.000
C83.7 Burkitt's tumour
0.709 0.291 0.000
C83.6 Undifferentiated (diffuse)
0.709 0.291 0.000
C83.5 Lymphoblastic (diffuse)
0.709 0.291 0.000
C83.4 Immunoblastic (diffuse)
0.709 0.291 0.000
C83.2 Mixed small and large cell (diffuse)
0.709 0.291 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.709 0.291 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.708 0.292 0.000
D50.1 Sideropenic dysphagia
0.000 0.293 0.707
D82 Immunodeficiency associated with other major defects
0.000 0.294 0.705
D81 Combined immunodeficiencies
0.000 0.294 0.705
C97 Malignant neoplasms of independent (primary) multiple sites
0.703 0.297 0.000
C44.1 Skin of eyelid, including canthus
0.703 0.297 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.298 0.702
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.298 0.702
D51.2 Transcobalamin II deficiency
0.000 0.298 0.702
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.298 0.702
L40.8 Other psoriasis
0.697 0.303 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.303 0.697
C11 Malignant neoplasm of nasopharynx
0.696 0.303 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.696 0.303 0.000
G35 Multiple sclerosis
0.000 0.305 0.695
C74.0 Cortex of adrenal gland
0.694 0.305 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.694 0.306 0.000
E14.9 Without complications
0.000 0.306 0.694
D69 Purpura and other haemorrhagic conditions
0.000 0.306 0.694
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.307 0.693
M06.34 Rheumatoid nodule (Hand)
0.693 0.307 0.000
C00 Malignant neoplasm of lip
0.693 0.307 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.690 0.310 0.000
E16.1 Other hypoglycaemia
0.000 0.315 0.685
D53 Other nutritional anaemias
0.000 0.316 0.684
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.318 0.682
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.318 0.682
E16.4 Abnormal secretion of gastrin
0.000 0.318 0.682
E16.3 Increased secretion of glucagon
0.000 0.318 0.682
M06.30 Rheumatoid nodule (Multiple sites)
0.681 0.319 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.323 0.676
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.323 0.676
K90.1 Tropical sprue
0.000 0.323 0.676
C02.8 Overlapping lesion of tongue
0.672 0.328 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.672 0.328 0.000
C02.0 Dorsal surface of tongue
0.672 0.328 0.000
E13 Other specified diabetes mellitus
0.000 0.329 0.671
E40-E46 Malnutrition
0.000 0.330 0.670
E21.0 Primary hyperparathyroidism
0.000 0.331 0.669
C83.1 Small cleaved cell (diffuse)
0.669 0.331 0.000
E27.2 Addisonian crisis
0.000 0.336 0.664
C85.1 B-cell lymphoma, unspecified
0.662 0.338 0.000
D83 Common variable immunodeficiency
0.000 0.338 0.661
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.339 0.661
D86.3 Sarcoidosis of skin
0.000 0.341 0.658
C04 Malignant neoplasm of floor of mouth
0.658 0.342 0.000
C43.8 Overlapping malignant melanoma of skin
0.655 0.345 0.000
C43.0 Malignant melanoma of lip
0.655 0.345 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.655 0.345 0.000
L40.0 Psoriasis vulgaris
0.652 0.348 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.651 0.349 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.650 0.350 0.000
M06.38 Rheumatoid nodule (Other)
0.650 0.350 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.650 0.350 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.650 0.350 0.000
M06.33 Rheumatoid nodule (Forearm)
0.650 0.350 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.650 0.350 0.000
C06.2 Retromolar area
0.648 0.352 0.000
E24 Cushing's syndrome
0.000 0.353 0.647
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.353 0.647
E32 Diseases of thymus
0.000 0.353 0.647
E31 Polyglandular dysfunction
0.000 0.353 0.647
E30 Disorders of puberty, not elsewhere classified
0.000 0.353 0.647
D69.6 Thrombocytopenia, unspecified
0.000 0.354 0.646
C44.9 Malignant neoplasm of skin, unspecified
0.646 0.354 0.000
L43.9 Lichen planus, unspecified
0.645 0.354 0.001
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.645 0.355 0.000
M05.8 Other seropositive rheumatoid arthritis
0.643 0.356 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.643 0.356 0.000
M05.2 Rheumatoid vasculitis
0.643 0.356 0.000
M05.1 Rheumatoid lung disease
0.643 0.356 0.000
M05.0 Felty's syndrome
0.643 0.356 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.639 0.361 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.361 0.639
C43.4 Malignant melanoma of scalp and neck
0.637 0.363 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.636 0.364 0.000
C01 Malignant neoplasm of base of tongue
0.634 0.365 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.366 0.634
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.366 0.634
E06 Thyroiditis
0.000 0.366 0.634
C06.9 Mouth, unspecified
0.633 0.367 0.000
D80 Immunodeficiency with predominantly antibody defects
0.000 0.368 0.632
C69 Malignant neoplasm of eye and adnexa
0.630 0.370 0.000
C44.6 Skin of upper limb, including shoulder
0.626 0.374 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.625 0.375 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.376 0.624
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.376 0.624
E27.0 Other adrenocortical overactivity
0.000 0.376 0.624
E50-E64 Other nutritional deficiencies
0.000 0.376 0.624
C95 Leukaemia of unspecified cell type
0.623 0.377 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.621 0.379 0.000
D52.8 Other folate deficiency anaemias
0.000 0.380 0.620
D52.1 Drug-induced folate deficiency anaemia
0.000 0.380 0.620
D52.0 Dietary folate deficiency anaemia
0.000 0.380 0.620
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.619 0.381 0.000
C74.1 Medulla of adrenal gland
0.613 0.386 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.612 0.387 0.000
D69.9 Haemorrhagic condition, unspecified
0.000 0.387 0.612
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.612 0.388 0.000
C06.1 Vestibule of mouth
0.612 0.388 0.000
C05.0 Hard palate
0.607 0.392 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.606 0.393 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.395 0.605
K50.0 Crohn's disease of small intestine
0.603 0.396 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.603 0.397 0.000
C88 Malignant immunoproliferative diseases
0.602 0.397 0.000
E14.8 With unspecified complications
0.000 0.401 0.599
E14.7 With multiple complications
0.000 0.401 0.599
E14.2 Withrenal complications
0.000 0.401 0.599
E14.1 With ketoacidosis
0.000 0.401 0.599
E14.0 With coma
0.000 0.401 0.599
C03.1 Lower gum
0.599 0.401 0.000
E07.8 Other specified disorders of thyroid
0.000 0.402 0.598
L44 Other papulosquamous disorders
0.589 0.403 0.008
L41 Parapsoriasis
0.589 0.403 0.008
L45 Papulosquamous disorders in diseases classified elsewhere
0.589 0.403 0.008
M06.4 Inflammatory polyarthropathy
0.594 0.406 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.591 0.409 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.591 0.409 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.591 0.409 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.591 0.409 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.591 0.409 0.000
E14.6 With other specified complications
0.000 0.409 0.591
C09.9 Tonsil, unspecified
0.588 0.412 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.414 0.586
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.418 0.582
T42.4 Benzodiazepines
0.581 0.419 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.579 0.421 0.000
E29.1 Testicular hypofunction
0.000 0.424 0.576
M11.9 Crystal arthropathy, unspecified
0.576 0.424 0.000
E07.1 Dyshormogenetic goitre
0.000 0.427 0.573
E07.0 Hypersecretion of calcitonin
0.000 0.427 0.573
C75.9 Endocrine gland, unspecified
0.571 0.429 0.000
C43.9 Malignant melanoma of skin, unspecified
0.571 0.429 0.000
D55-D59 Haemolytic anaemias
0.001 0.429 0.570
D84 Other immunodeficiencies
0.001 0.431 0.568
K51.3 Ulcerative (chronic) rectosigmoiditis
0.569 0.431 0.000
E25 Adrenogenital disorders
0.000 0.432 0.568
J45.8 Mixed asthma
0.000 0.434 0.566
J45.1 Nonallergic asthma
0.000 0.434 0.566
C13.9 Hypopharynx, unspecified
0.565 0.434 0.000
C64-C68 Malignant neoplasms of urinary tract
0.565 0.434 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.565 0.435 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.563 0.437 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.437 0.562
C43.2 Malignant melanoma of ear and external auricular canal
0.560 0.440 0.000
E14.5 With peripheral circulatory complications
0.000 0.441 0.559
C10.9 Oropharynx, unspecified
0.554 0.446 0.000
D69.4 Other primary thrombocytopenia
0.000 0.450 0.550
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.450 0.549
E22.8 Other hyperfunction of pituitary gland
0.000 0.450 0.549
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.548 0.451 0.000
C69.9 Eye, unspecified
0.548 0.452 0.000
E22.1 Hyperprolactinaemia
0.000 0.453 0.547
D67 Hereditary factor IX deficiency
0.000 0.453 0.547
M12.2 Villonodular synovitis (pigmented)
0.546 0.454 0.000
M14.6 Neuropathic arthropathy
0.544 0.455 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.544 0.455 0.000
C83.0 Small cell (diffuse)
0.542 0.458 0.000
C03.9 Gum, unspecified
0.541 0.459 0.000
C03.0 Upper gum
0.541 0.459 0.000
C05.9 Palate, unspecified
0.537 0.463 0.000
C05.8 Overlapping lesion of palate
0.537 0.463 0.000
C05.2 Uvula
0.537 0.463 0.000
C09.8 Overlapping lesion of tonsil
0.536 0.464 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.536 0.464 0.000
C09.0 Tonsillar fossa
0.536 0.464 0.000
M11.8 Other specified crystal arthropathies
0.536 0.464 0.000
M11.1 Familial chondrocalcinosis
0.536 0.464 0.000
M11.0 Hydroxyapatite deposition disease
0.536 0.464 0.000
C75.8 Pluriglandular involvement, unspecified
0.535 0.465 0.000
C75.5 Aortic body and other paraganglia
0.535 0.465 0.000
C75.4 Carotid body
0.535 0.465 0.000
C75.3 Pineal gland
0.535 0.465 0.000
C75.2 Craniopharyngeal duct
0.535 0.465 0.000
C75.1 Pituitary gland
0.535 0.465 0.000
C75.0 Parathyroid gland
0.535 0.465 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.534 0.466 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.468 0.532
E21.2 Other hyperparathyroidism
0.000 0.468 0.532
E34 Other endocrine disorders
0.000 0.469 0.531
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.469 0.531
M12.8 Other specific arthropathies, not elsewhere classified
0.527 0.473 0.000
M12.5 Traumatic arthropathy
0.527 0.473 0.000
M12.4 Intermittent hydrarthrosis
0.527 0.473 0.000
M12.3 Palindromic rheumatism
0.527 0.473 0.000
M12.1 Kaschin-Beck disease
0.527 0.473 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.527 0.473 0.000
C84.5 Other and unspecified T-cell lymphomas
0.527 0.473 0.000
C13.8 Overlapping lesion of hypopharynx
0.527 0.473 0.000
C13.2 Posterior wall of hypopharynx
0.527 0.473 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.527 0.473 0.000
C13.0 Postcricoid region
0.527 0.473 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.527 0.473 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.527 0.473 0.000
M14.4 Arthropathy in amyloidosis
0.527 0.473 0.000
M14.3 Lipoid dermatoarthritis
0.527 0.473 0.000
M14.2 Diabetic arthropathy
0.527 0.473 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.527 0.473 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.527 0.473 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.526 0.474 0.000
K52 Other non-infective gastro-enteritis and colitis
0.526 0.474 0.000
M11.2 Other chondrocalcinosis
0.524 0.476 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.524 0.476 0.000
E20.8 Other hypoparathyroidism
0.000 0.477 0.523
E20.1 Pseudohypoparathyroidism
0.000 0.477 0.523
E20.0 Idiopathic hypoparathyroidism
0.000 0.477 0.523
C10.8 Overlapping lesion of oropharynx
0.522 0.478 0.000
C10.4 Branchial cleft
0.522 0.478 0.000
C10.3 Posterior wall of oropharynx
0.522 0.478 0.000
C10.2 Lateral wall of oropharynx
0.522 0.478 0.000
C10.1 Anterior surface of epiglottis
0.522 0.478 0.000
C10.0 Vallecula
0.522 0.478 0.000
C70 Malignant neoplasm of meninges
0.521 0.479 0.000
C84.0 Mycosis fungoides
0.518 0.481 0.000
L43.3 Subacute (active) lichen planus
0.515 0.482 0.004
L43.2 Lichenoid drug reaction
0.515 0.482 0.004
L43.1 Bullous lichen planus
0.515 0.482 0.004
L43.0 Hypertrophic lichen planus
0.515 0.482 0.004
L43.8 Other lichen planus
0.514 0.483 0.003
C84.9 Mature T/NK-cell lymphoma, unspecified
0.515 0.485 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.515 0.485 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.515 0.485 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.515 0.485 0.000
C84.3 Lymphoepithelioid lymphoma
0.515 0.485 0.000
C84.2 T-zone lymphoma
0.515 0.485 0.000
C84.1 Sezary's diease
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.514 0.486 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.514 0.486 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.514 0.486 0.000
C86.4 Blastic NK-cell lymphoma
0.514 0.486 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.514 0.486 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.514 0.486 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.514 0.486 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.514 0.486 0.000
C93.9 Monocytic leukaemia, unspecified
0.514 0.486 0.000
C93.7 Other monocytic leukaemia
0.514 0.486 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.514 0.486 0.000
C93.2 Subacute monocytic leukaemia
0.514 0.486 0.000
C93.1 Chronic monocytic leukaemia
0.514 0.486 0.000
C93.0 Acute monocytic leukaemia
0.514 0.486 0.000
C94.7 Other specified leukaemias
0.514 0.486 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.514 0.486 0.000
C94.5 Acute myelofibrosis
0.514 0.486 0.000
C94.4 Acute panmyelosis
0.514 0.486 0.000
C94.3 Mast cell leukaemia
0.514 0.486 0.000
C94.2 Acute megakaryoblastic leukaemia
0.514 0.486 0.000
C94.1 Chronic erythraemia
0.514 0.486 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.514 0.486 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.514 0.486 0.000
C96.8 Histiocytic sarcoma
0.514 0.486 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.514 0.486 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.514 0.486 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.514 0.486 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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