TreeWAS – Variant ID: rs13271456

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.935	0.065
K02.9 Dental caries, unspecified	0.000	0.940	0.060
O63.1 Prolonged second stage (of labour)	0.052	0.948	0.000
O63 Long labour	0.036	0.964	0.000
K02 Dental caries	0.000	0.969	0.031
O60-O75 Complications of labour and delivery	0.030	0.970	0.000
K44 Diaphragmatic hernia	0.000	0.972	0.028
O62 Abnormalities of forces of labour	0.028	0.972	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.026	0.974	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.025	0.975	0.000
O62.3 Precipitate labour	0.025	0.975	0.000
O63.9 Long labour, unspecified	0.025	0.975	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.024	0.976	0.000
K02.8 Other dental caries	0.000	0.976	0.024
O70 Perineal laceration during delivery	0.024	0.976	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.023	0.977	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.023	0.977	0.000
K02.5 Caries with pulp exposure	0.000	0.977	0.022
K02.4 Odontoclasia	0.000	0.977	0.022
K02.3 Arrested dental caries	0.000	0.977	0.022
K02.2 Caries of cementum	0.000	0.977	0.022
K02.1 Caries of dentin	0.000	0.977	0.022
K02.0 Caries limited to enamel	0.000	0.977	0.022
O64 Obstructed labour due to malposition and malpresentation of foetus	0.022	0.977	0.000
O71 Other obstetric trauma	0.022	0.978	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.022	0.978	0.000
O62.2 Other uterine inertia	0.022	0.978	0.000
O74 Complications of anaesthesia during labour and delivery	0.021	0.978	0.000
O60 Preterm delivery	0.021	0.978	0.000
O70.1 Second degree perineal laceration during delivery	0.021	0.979	0.000
O70.2 Third degree perineal laceration during delivery	0.021	0.979	0.000
K44.1 Diaphragmatic hernia with gangrene	0.000	0.979	0.021
O62.0 Primary inadequate contractions	0.021	0.979	0.000
O73 Retained placenta and membranes, without haemorrhage	0.020	0.980	0.000
O62.9 Abnormality of forces of labour, unspecified	0.020	0.980	0.000
O62.8 Other abnormalities of forces of labour	0.020	0.980	0.000
O62.1 Secondary uterine inertia	0.020	0.980	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.020	0.980	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.980	0.020
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.020	0.980	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.020	0.980	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.020	0.980	0.000
O63.0 Prolonged first stage (of labour)	0.020	0.980	0.000
O69.8 Labour and delivery complicated by other cord complications	0.019	0.981	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.019	0.981	0.000
O72 Postpartum haemorrhage	0.019	0.981	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.019	0.981	0.000
O61 Failed induction of labour	0.019	0.981	0.000
O66 Other obstructed labour	0.018	0.982	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.018	0.982	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.018	0.982	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.018	0.982	0.000
O69.3 Labour and delivery complicated by short cord	0.018	0.982	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.018	0.982	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.017	0.982	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.017	0.982	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.017	0.982	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.017	0.982	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.017	0.982	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.017	0.982	0.000
O65.0 Obstructed labour due to deformed pelvis	0.017	0.982	0.000
H33.3 Retinal breaks without detachment	0.000	0.982	0.018
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.017	0.983	0.000
O70.3 Fourth degree perineal laceration during delivery	0.017	0.983	0.000
O71.8 Other specified obstetric trauma	0.017	0.983	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.016	0.983	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.016	0.984	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.016	0.984	0.000
O64.5 Obstructed labour due to compound presentation	0.016	0.984	0.000
O64.4 Obstructed labour due to shoulder presentation	0.016	0.984	0.000
O64.3 Obstructed labour due to brow presentation	0.016	0.984	0.000
O64.2 Obstructed labour due to face presentation	0.016	0.984	0.000
O64.1 Obstructed labour due to breech presentation	0.016	0.984	0.000
O71.9 Obstetric trauma, unspecified	0.016	0.984	0.000
O71.7 Obstetric haematoma of pelvis	0.016	0.984	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.016	0.984	0.000
O71.5 Other obstetric injury to pelvic organs	0.016	0.984	0.000
O71.4 Obstetric high vaginal laceration alone	0.016	0.984	0.000
O71.3 Obstetric laceration of cervix	0.016	0.984	0.000
O71.2 Postpartum inversion of uterus	0.016	0.984	0.000
O71.1 Rupture of uterus during labour	0.016	0.984	0.000
O71.0 Rupture of uterus before onset of labour	0.016	0.984	0.000
O70.9 Perineal laceration during delivery, unspecified	0.016	0.984	0.000
O60.3 Preterm delivery without spontaneous labour	0.016	0.984	0.000
O60.2 Preterm spontaneous labour with term delivery	0.016	0.984	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.016	0.984	0.000
O60.0 Preterm labour without delivery	0.016	0.984	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.016	0.984	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.016	0.984	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.016	0.984	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.016	0.984	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.016	0.984	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.016	0.984	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.016	0.984	0.000
O75.8 Other specified complications of labour and delivery	0.015	0.985	0.000
H33.0 Retinal detachment with retinal break	0.000	0.985	0.015
O72.0 Third-stage haemorrhage	0.015	0.985	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.015	0.985	0.000
O67.8 Other intrapartum haemorrhage	0.015	0.985	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.015	0.985	0.000
H33 Retinal detachments and breaks	0.000	0.985	0.015
O75.2 Pyrexia during labour, not elsewhere classified	0.015	0.985	0.000
O75.9 Complication of labour and delivery, unspecified	0.014	0.985	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.014	0.985	0.000
O75.4 Other complications of obstetric surgery and procedures	0.014	0.985	0.000
O75.3 Other infection during labour	0.014	0.985	0.000
O75.1 Shock during or following labour and delivery	0.014	0.985	0.000
O75.0 Maternal distress during labour and delivery	0.014	0.985	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.014	0.986	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.014	0.986	0.000
O72.3 Postpartum coagulation defects	0.014	0.986	0.000
O61.9 Failed induction of labour, unspecified	0.014	0.986	0.000
O61.8 Other failed induction of labour	0.014	0.986	0.000
O61.1 Failed instrumental induction of labour	0.014	0.986	0.000
O73.0 Retained placenta, without haemorrhage	0.014	0.986	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.013	0.986	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.013	0.986	0.000
E10 Insulin-dependent diabetes mellitus	0.014	0.986	0.000
O66.9 Obstructed labour, unspecified	0.013	0.986	0.000
O66.8 Other specified obstructed labour	0.013	0.986	0.000
O66.4 Failed trial of labour, unspecified	0.013	0.986	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.013	0.986	0.000
O66.2 Obstructed labour due to unusually large foetus	0.013	0.986	0.000
O66.1 Obstructed labour due to locked twins	0.013	0.986	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.013	0.987	0.000
E10.4 With neurological complications	0.013	0.987	0.000
E10.3 With ophthalmic complications	0.013	0.987	0.000
E10.9 Without complications	0.012	0.988	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.012	0.988	0.000
E10.2 With renal complications	0.012	0.988	0.000
E10.5 With peripheral circulatory complications	0.012	0.988	0.000
O72.1 Other immediate postpartum haemorrhage	0.011	0.989	0.000
H33.2 Serous retinal detachment	0.000	0.989	0.011
O61.0 Failed medical induction of labour	0.011	0.989	0.000
H33.4 Traction detachment of retina	0.000	0.989	0.011
H33.1 Retinoschisis and retinal cysts	0.000	0.989	0.011
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.010	0.990	0.000
E10.8 With unspecified complications	0.010	0.990	0.000
E10.7 With multiple complications	0.010	0.990	0.000
E10.6 With other specified complications	0.010	0.990	0.000
E10.0 With coma	0.010	0.990	0.000
L03.1 Cellulitis of other parts of limb	0.000	0.990	0.010
H33.5 Other retinal detachments	0.000	0.991	0.009
Chapter XV Pregnancy, childbirth and the puerperium	0.009	0.991	0.000
E10.1 With ketoacidosis	0.009	0.991	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.009	0.991	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.009	0.991	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.992	0.008
M35.0 Sicca syndrome [Sjogren]	0.000	0.992	0.008
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.992	0.008
O20-O29 Other maternal disorders predominantly related to pregnancy	0.008	0.992	0.000
O85-O92 Complications predominantly related to the puerperium	0.007	0.993	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.000	0.993	0.007
O80-O84 Delivery	0.007	0.993	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.007	0.993	0.000
K13 Other diseases of lip and oral mucosa	0.000	0.993	0.007
O23 Infections of genito-urinary tract in pregnancy	0.007	0.993	0.000
O00-O08 Pregnancy with abortive outcome	0.007	0.993	0.000
L03 Cellulitis	0.000	0.993	0.007
E10-E14 Diabetes mellitus	0.007	0.993	0.000
O21 Excessive vomiting in pregnancy	0.006	0.993	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.006	0.994	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.006	0.994	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.006	0.994	0.000
I34.1 Mitral (valve) prolapse	0.000	0.994	0.006
O00 Ectopic pregnancy	0.006	0.994	0.000
K05 Gingivitis and periodontal diseases	0.000	0.994	0.006
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
O23.5 Infections of the genital tract in pregnancy	0.006	0.994	0.000
K05.3 Chronic periodontitis	0.000	0.994	0.006
O86 Other puerperal infections	0.006	0.994	0.000
O28 Abnormal findings on antenatal screening of mother	0.006	0.994	0.000
L03.0 Cellulitis of finger and toe	0.000	0.994	0.006
Y43 Primarily systemic agents	0.006	0.994	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.006	0.994	0.000
O34.4 Maternal care for other abnormalities of cervix	0.006	0.994	0.000
O34.1 Maternal care for tumour of corpus uteri	0.006	0.994	0.000
Y45.5 4-Aminophenol derivatives	0.006	0.994	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.006	0.994	0.000
K00 Disorders of tooth development and eruption	0.000	0.994	0.006
L03.3 Cellulitis of trunk	0.000	0.994	0.006
O21.2 Late vomiting of pregnancy	0.006	0.994	0.000
O00.1 Tubal pregnancy	0.006	0.994	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.994	0.006
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.994	0.006
O29 Complications of anaesthesia during pregnancy	0.006	0.994	0.000
O22 Venous complications in pregnancy	0.006	0.994	0.000
O25 Malnutrition in pregnancy	0.006	0.994	0.000
Y40 Systemic antibiotics	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.006	0.994	0.000
L03.9 Cellulitis, unspecified	0.000	0.994	0.006
O24 Diabetes mellitus in pregnancy	0.005	0.994	0.000
Y41.0 Sulphonamides	0.005	0.994	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.005	0.995	0.000
E14 Unspecified diabetes mellitus	0.005	0.995	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.005	0.995	0.000
K11 Diseases of salivary glands	0.000	0.995	0.005
O92 Other disorders of breast and lactation associated with childbirth	0.005	0.995	0.000
O91 Infections of breast associated with childbirth	0.005	0.995	0.000
O89 Complications of anaesthesia during the puerperium	0.005	0.995	0.000
O88 Obstetric embolism	0.005	0.995	0.000
O87 Venous complications in the puerperium	0.005	0.995	0.000
O85 Puerperal sepsis	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
K03 Other diseases of hard tissues of teeth	0.000	0.995	0.005
E13 Other specified diabetes mellitus	0.005	0.995	0.000
O80 Single spontaneous delivery	0.005	0.995	0.000
O84 Multiple delivery	0.005	0.995	0.000
O83 Other assisted single delivery	0.005	0.995	0.000
O81 Single delivery by forceps and vacuum extractor	0.005	0.995	0.000
O15 Eclampsia	0.005	0.995	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.005	0.995	0.000
O82 Single delivery by Caesarean section	0.005	0.995	0.000
L03.8 Cellulitis of other sites	0.000	0.995	0.005
K14 Diseases of tongue	0.000	0.995	0.005
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.995	0.005
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.995	0.005
K13.5 Oral submucous fibrosis	0.000	0.995	0.005
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.995	0.005
K13.3 Hairy leukoplakia	0.000	0.995	0.005
K13.1 Cheek and lip biting	0.000	0.995	0.005
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.995	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.005	0.995	0.000
O23.2 Infections of urethra in pregnancy	0.005	0.995	0.000
O23.1 Infections of bladder in pregnancy	0.005	0.995	0.000
O23.0 Infections of kidney in pregnancy	0.005	0.995	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.005	0.995	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.005	0.995	0.000
O07 Failed attempted abortion	0.005	0.995	0.000
O06 Unspecified abortion	0.005	0.995	0.000
O05 Other abortion	0.005	0.995	0.000
O01 Hydatidiform mole	0.005	0.995	0.000
O14.0 Moderate preeclampsia	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
K07 Dentofacial anomalies [including malocclusion]	0.000	0.995	0.005
Y49 Psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
O21.0 Mild hyperemesis gravidarum	0.005	0.995	0.000
Y45.0 Opioids and related analgesics	0.005	0.995	0.000
O86.2 Urinary tract infection following delivery	0.005	0.995	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.005	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.005	0.995	0.000
Y40.3 Macrolides	0.005	0.995	0.000
Y43.3 Other antineoplastic drugs	0.005	0.995	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
K10 Other diseases of jaws	0.000	0.995	0.005
E12 Malnutrition-related diabetes mellitus	0.005	0.995	0.000
O00.9 Ectopic pregnancy, unspecified	0.005	0.995	0.000
O21.9 Vomiting of pregnancy, unspecified	0.005	0.995	0.000
O21.8 Other vomiting complicating pregnancy	0.005	0.995	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.005	0.995	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.000	0.995	0.005
E14.3 With ophthalmic complications	0.005	0.995	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.995	0.000
Y58 Bacterial vaccines	0.005	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.005	0.995	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.005	0.995	0.000
O04 Medical abortion	0.005	0.995	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.005	0.995	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.005	0.995	0.000
O34.6 Maternal care for abnormality of vagina	0.005	0.995	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.005	0.995	0.000
O34.3 Maternal care for cervical incompetence	0.005	0.995	0.000
O34.0 Maternal care for congenital malformation of uterus	0.005	0.995	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.005	0.995	0.000
Y45.8 Other analgesics and antipyretics	0.005	0.995	0.000
Y45.4 Antirheumatics	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.005	0.995	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.005	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.005	0.995	0.000
K00.6 Disturbances in tooth eruption	0.000	0.995	0.005
K14.0 Glossitis	0.000	0.995	0.005
O47 False labour	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.005	0.995	0.000
O00.8 Other ectopic pregnancy	0.005	0.995	0.000
O00.2 Ovarian pregnancy	0.005	0.995	0.000
O00.0 Abdominal pregnancy	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.005	0.995	0.000
K05.2 Acute periodontitis	0.000	0.995	0.005
K05.5 Other periodontal diseases	0.000	0.995	0.005
K05.4 Periodontosis	0.000	0.995	0.005
K05.0 Acute gingivitis	0.000	0.995	0.005
O44 Placenta praevia	0.005	0.995	0.000
O86.0 Infection of obstetric surgical wound	0.004	0.995	0.000
Y43.4 Immunosuppressive agents	0.005	0.995	0.000
K07.6 Temporomandibular joint disorders	0.000	0.995	0.005
K12 Stomatitis and related lesions	0.000	0.995	0.005
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.004	0.995	0.000
O80.8 Other single spontaneous delivery	0.004	0.995	0.000
Y40.8 Other systemic antibiotics	0.004	0.995	0.000
Y48.3 Local anaesthetics	0.004	0.995	0.000
O86.8 Other specified puerperal infections	0.004	0.995	0.000
O86.4 Pyrexia of unknown origin following delivery	0.004	0.995	0.000
O86.3 Other genito-urinary tract infections following delivery	0.004	0.995	0.000
O86.1 Other infection of genital tract following delivery	0.004	0.995	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.995	0.000
K05.6 Periodontal disease, unspecified	0.000	0.995	0.004
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.004	0.995	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.004	0.995	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.004	0.995	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.004	0.995	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.004	0.995	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.004	0.995	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.004	0.995	0.000
Y45.2 Propionic acid derivatives	0.004	0.995	0.000
H30-H36 Disorders of choroid and retina	0.000	0.995	0.005
Y43.9 Primarily systemic agent, unspecified	0.004	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.995	0.000
Y43.2 Antineoplastic natural products	0.004	0.995	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.995	0.000
Y41.5 Antiviral drugs	0.004	0.995	0.000
Y41.4 Anthelminthics	0.004	0.995	0.000
Y41.3 Other antiprotozoal drugs	0.004	0.995	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.995	0.000
Y41.1 Antimycobacterial drugs	0.004	0.995	0.000
L03.2 Cellulitis of face	0.000	0.996	0.004
O40 Polyhydramnios	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
O02 Other abnormal products of conception	0.004	0.996	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.004	0.996	0.000
O80.0 Spontaneous vertex delivery	0.004	0.996	0.000
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
K00.9 Disorder of tooth development, unspecified	0.000	0.996	0.004
K00.8 Other disorders of tooth development	0.000	0.996	0.004
K00.7 Teething syndrome	0.000	0.996	0.004
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.000	0.996	0.004
K00.4 Disturbances in tooth formation	0.000	0.996	0.004
K00.3 Mottled teeth	0.000	0.996	0.004
K00.2 Abnormalities of size and form of teeth	0.000	0.996	0.004
K00.1 Supernumerary teeth	0.000	0.996	0.004
K00.0 Anodontia	0.000	0.996	0.004
E13.9 Without complications	0.004	0.996	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.996	0.004
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.996	0.004
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
O03 Spontaneous abortion	0.004	0.996	0.000
Y43.1 Antineoplastic antimetabolites	0.004	0.996	0.000
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
O22.9 Venous complication in pregnancy, unspecified	0.004	0.996	0.000
O22.8 Other venous complications in pregnancy	0.004	0.996	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.004	0.996	0.000
O22.4 Haemorrhoids in pregnancy	0.004	0.996	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.004	0.996	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.004	0.996	0.000
O22.1 Genital varices in pregnancy	0.004	0.996	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.004	0.996	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.004	0.996	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.6 Failed or difficult intubation during pregnancy	0.004	0.996	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.004	0.996	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.004	0.996	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.004	0.996	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.004	0.996	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.004	0.996	0.000
Y40.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
Y40.6 Rifamycins	0.004	0.996	0.000
Y40.5 Aminoglycosides	0.004	0.996	0.000
Y40.4 Tetracyclines	0.004	0.996	0.000
Y40.2 Chloramphenicol group	0.004	0.996	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.996	0.004
O14.2 HELLP syndrome	0.004	0.996	0.000
O14.1 Severe preeclampsia	0.004	0.996	0.000
K11.5 Sialolithiasis	0.000	0.996	0.004
Y45.1 Salicylates	0.004	0.996	0.000
K11.6 Mucocele of salivary gland	0.000	0.996	0.004
O82.0 Delivery by elective Caesarean section	0.004	0.996	0.000
E11 Non-insulin-dependent diabetes mellitus	0.004	0.996	0.000
Y95 Nosocomial condition	0.004	0.996	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.004	0.996	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.004	0.996	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.004	0.996	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.004	0.996	0.000
E11.3 With ophthalmic complications	0.004	0.996	0.000
O33.9 Maternal care for disproportion, unspecified	0.004	0.996	0.000
K09 Cysts of oral region, not elsewhere classified	0.000	0.996	0.004
O43 Placental disorders	0.004	0.996	0.000
Y49.2 Other and unspecified antidepressants	0.004	0.996	0.000
E14.8 With unspecified complications	0.004	0.996	0.000
E14.7 With multiple complications	0.004	0.996	0.000
E14.6 With other specified complications	0.004	0.996	0.000
E14.5 With peripheral circulatory complications	0.004	0.996	0.000
E14.4 With neurological complications	0.004	0.996	0.000
E14.2 Withrenal complications	0.004	0.996	0.000
E14.1 With ketoacidosis	0.004	0.996	0.000
E14.0 With coma	0.004	0.996	0.000
K11.9 Disease of salivary gland, unspecified	0.000	0.996	0.004
K11.8 Other diseases of salivary glands	0.000	0.996	0.004
K11.7 Disturbances of salivary secretion	0.000	0.996	0.004
K11.4 Fistula of salivary gland	0.000	0.996	0.004
K11.3 Abscess of salivary gland	0.000	0.996	0.004
K11.0 Atrophy of salivary gland	0.000	0.996	0.004
O87.9 Venous complication in the puerperium, unspecified	0.004	0.996	0.000
O87.8 Other venous complications in the puerperium	0.004	0.996	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.004	0.996	0.000
O87.2 Haemorrhoids in the puerperium	0.004	0.996	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.004	0.996	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.004	0.996	0.000
O88.8 Other obstetric embolism	0.004	0.996	0.000
O88.3 Obstetric pyaemic and septic embolism	0.004	0.996	0.000
O88.2 Obstetric blood-clot embolism	0.004	0.996	0.000
O88.1 Amniotic fluid embolism	0.004	0.996	0.000
O88.0 Obstetric air embolism	0.004	0.996	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.004	0.996	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.004	0.996	0.000
O89.6 Failed or difficult intubation during the puerperium	0.004	0.996	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.004	0.996	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.004	0.996	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.004	0.996	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.004	0.996	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.004	0.996	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.004	0.996	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.004	0.996	0.000
O91.1 Abscess of breast associated with childbirth	0.004	0.996	0.000
O91.0 Infection of nipple associated with childbirth	0.004	0.996	0.000
O92.7 Other and unspecified disorders of lactation	0.004	0.996	0.000
O92.6 Galactorrhoea	0.004	0.996	0.000
O92.5 Suppressed lactation	0.004	0.996	0.000
O92.4 Hypogalactia	0.004	0.996	0.000
O92.3 Agalactia	0.004	0.996	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.004	0.996	0.000
O92.1 Cracked nipple associated with childbirth	0.004	0.996	0.000
O92.0 Retracted nipple associated with childbirth	0.004	0.996	0.000
K12.1 Other forms of stomatitis	0.000	0.996	0.004
O82.9 Delivery by Caesarean section, unspecified	0.004	0.996	0.000
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
O20 Haemorrhage in early pregnancy	0.004	0.996	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.000	0.996	0.004
K03.8 Other specified diseases of hard tissues of teeth	0.000	0.996	0.004
K03.7 Posteruptive colour changes of dental hard tissues	0.000	0.996	0.004
K03.6 Deposits [accretions] on teeth	0.000	0.996	0.004
K03.5 Ankylosis of teeth	0.000	0.996	0.004
K03.4 Hypercementosis	0.000	0.996	0.004
K03.3 Pathological resorption of teeth	0.000	0.996	0.004
K03.2 Erosion of teeth	0.000	0.996	0.004
K03.1 Abrasion of teeth	0.000	0.996	0.004
K03.0 Excessive attrition of teeth	0.000	0.996	0.004
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
E13.8 With unspecified complications	0.004	0.996	0.000
E13.7 With multiple complications	0.004	0.996	0.000
E13.6 With other specified complications	0.004	0.996	0.000
E13.5 With peripheral circulatory complications	0.004	0.996	0.000
E13.4 With neurological complications	0.004	0.996	0.000
E13.3 With ophthalmic complications	0.004	0.996	0.000
E13.2 With renal complications	0.004	0.996	0.000
E13.1 With ketoacidosis	0.004	0.996	0.000
E13.0 With coma	0.004	0.996	0.000
O80.1 Spontaneous breech delivery	0.004	0.996	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.004	0.996	0.000
O81.4 Vacuum extractor delivery	0.004	0.996	0.000
O81.3 Other and unspecified forceps delivery	0.004	0.996	0.000
O81.2 Mid-cavity forceps with rotation	0.004	0.996	0.000
O81.1 Mid-cavity forceps delivery	0.004	0.996	0.000
O81.0 Low forceps delivery	0.004	0.996	0.000
O83.9 Assisted single delivery, unspecified	0.004	0.996	0.000
O83.8 Other specified assisted single delivery	0.004	0.996	0.000
O83.4 Destructive operation for delivery	0.004	0.996	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.004	0.996	0.000
O83.2 Other manipulation-assisted delivery	0.004	0.996	0.000
O83.1 Other assisted breech delivery	0.004	0.996	0.000
O83.0 Breech extraction	0.004	0.996	0.000
O84.9 Multiple delivery, unspecified	0.004	0.996	0.000
O84.8 Other multiple delivery	0.004	0.996	0.000
O84.2 Multiple delivery, all by Caesarean section	0.004	0.996	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.004	0.996	0.000
O84.0 Multiple delivery, all spontaneous	0.004	0.996	0.000
K05.1 Chronic gingivitis	0.000	0.996	0.004
K10.2 Inflammatory conditions of jaws	0.000	0.996	0.004
O47.0 False labour before 37 completed weeks of gestation	0.004	0.996	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations