TreeWAS – Variant ID: rs1335515

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27.4 Other and unspecified adrenocortical insufficiency	0.041	0.959	0.000
E27 Other disorders of adrenal gland	0.025	0.975	0.000
Q27.3 Peripheral arteriovenous malformation	0.025	0.975	0.000
Q27 Other congenital malformations of peripheral vascular system	0.023	0.977	0.000
E27.1 Primary adrenocortical insufficiency	0.022	0.978	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.021	0.979	0.000
E27.9 Disorder of adrenal gland, unspecified	0.020	0.980	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.019	0.981	0.000
E27.5 Adrenomedullary hyperfunction	0.018	0.982	0.000
E27.0 Other adrenocortical overactivity	0.018	0.982	0.000
E27.2 Addisonian crisis	0.018	0.982	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.018	0.982	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.018	0.982	0.000
H01.0 Blepharitis	0.000	0.982	0.018
Q23 Congenital malformations of aortic and mitral valves	0.017	0.983	0.000
Q23.1 Congenital insufficiency of aortic valve	0.016	0.984	0.000
Q27.4 Congenital phlebectasia	0.016	0.984	0.000
Q27.2 Other congenital malformations of renal artery	0.016	0.984	0.000
Q27.1 Congenital renal artery stenosis	0.016	0.984	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.016	0.984	0.000
T39.1 4-Aminophenol derivatives	0.000	0.984	0.016
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.984	0.016
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.985	0.015
Q28 Other congenital malformations of circulatory system	0.015	0.985	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.014	0.986	0.000
Q24 Other congenital malformations of heart	0.014	0.986	0.000
Q25 Congenital malformations of great arteries	0.013	0.987	0.000
Q26 Congenital malformations of great veins	0.013	0.987	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.013	0.987	0.000
D23.5 Skin of trunk	0.000	0.987	0.013
Q28.2 Arteriovenous malformation of cerebral vessels	0.013	0.987	0.000
Q23.0 Congenital stenosis of aortic valve	0.013	0.987	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.012	0.988	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.012	0.988	0.000
Q23.4 Hypoplastic left heart syndrome	0.012	0.988	0.000
Q23.3 Congenital mitral insufficiency	0.012	0.988	0.000
Q23.2 Congenital mitral stenosis	0.012	0.988	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.988	0.012
G25.0 Essential tremor	0.012	0.988	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.988	0.012
Q24.9 Congenital malformation of the heart, unspecified	0.011	0.988	0.000
Q28.3 Other malformations of cerebral vessels	0.011	0.989	0.000
Q22.1 Congenital pulmonary valve stenosis	0.011	0.989	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.989	0.011
T39.2 Pyrazolone derivatives	0.000	0.989	0.011
Q28.9 Congenital malformation of circulatory system, unspecified	0.011	0.989	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.011	0.989	0.000
Q28.1 Other malformations of precerebral vessels	0.011	0.989	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.011	0.989	0.000
Q24.5 Malformation of coronary vessels	0.011	0.989	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.010	0.990	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.010	0.990	0.000
Q22.6 Hypoplastic right heart syndrome	0.010	0.990	0.000
Q22.4 Congenital tricuspid stenosis	0.010	0.990	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.010	0.990	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.010	0.990	0.000
Q22.0 Pulmonary valve atresia	0.010	0.990	0.000
Q22.5 Ebstein's anomaly	0.010	0.990	0.000
Q24.6 Congenital heart block	0.010	0.990	0.000
Q24.4 Congenital subaortic stenosis	0.010	0.990	0.000
Q24.3 Pulmonary infundibular stenosis	0.010	0.990	0.000
Q24.2 Cor triatriatum	0.010	0.990	0.000
Q24.1 Levocardia	0.010	0.990	0.000
Q24.0 Dextrocardia	0.010	0.990	0.000
Q25.0 Patent ductus arteriosus	0.010	0.990	0.000
Q25.3 Stenosis of aorta	0.010	0.990	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.010	0.990	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.009	0.990	0.000
Q25.8 Other congenital malformations of great arteries	0.009	0.990	0.000
Q25.6 Stenosis of pulmonary artery	0.009	0.990	0.000
Q25.5 Atresia of pulmonary artery	0.009	0.990	0.000
Q25.2 Atresia of aorta	0.009	0.990	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.009	0.990	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.009	0.990	0.000
Q20.6 Isomerism of atrial appendages	0.009	0.990	0.000
Q20.5 Discordant atrioventricular connexion	0.009	0.990	0.000
Q20.4 Double inlet ventricle	0.009	0.990	0.000
Q20.3 Discordant ventriculoarterial connexion	0.009	0.990	0.000
Q20.2 Double outlet left ventricle	0.009	0.990	0.000
Q20.1 Double outlet right ventricle	0.009	0.990	0.000
Q20.0 Common arterial trunk	0.009	0.990	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.009	0.990	0.000
Q26.8 Other congenital malformations of great veins	0.009	0.990	0.000
Q26.6 Portal vein-hepatic artery fistula	0.009	0.990	0.000
Q26.5 Anomalous portal venous connexion	0.009	0.990	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.009	0.990	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.009	0.990	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.009	0.990	0.000
Q26.1 Persistent left superior vena cava	0.009	0.990	0.000
Q26.0 Congenital stenosis of vena cava	0.009	0.990	0.000
T39.0 Salicylates	0.000	0.990	0.010
Q25.4 Other congenital malformations of aorta	0.009	0.991	0.000
E27.8 Other specified disorders of adrenal gland	0.009	0.991	0.001
Q25.1 Coarctation of aorta	0.009	0.991	0.000
Q24.8 Other specified congenital malformations of heart	0.009	0.991	0.000
O62.2 Other uterine inertia	0.000	0.992	0.008
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.992	0.008
Q21 Congenital malformations of cardiac septa	0.007	0.993	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.993	0.007
C78.7 Secondary malignant neoplasm of liver	0.007	0.993	0.000
B07 Viral warts	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.000	0.994	0.006
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.994	0.006
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.994	0.006
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.006	0.994	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.994	0.006
K09.0 Developmental odontogenic cysts	0.000	0.994	0.006
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.005	0.994	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.005	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.005	0.995	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
T40.4 Other synthetic narcotics	0.000	0.995	0.005
T36 Poisoning by systemic antibiotics	0.000	0.995	0.005
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.995	0.005
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
Q89 Other congenital malformations, not elsewhere classified	0.005	0.995	0.000
K83.8 Other specified diseases of biliary tract	0.000	0.995	0.005
Q80-Q89 Other congenital malformations	0.005	0.995	0.000
T50.8 Diagnostic agents	0.000	0.995	0.005
T50.7 Analeptics and opioid receptor antagonists	0.000	0.995	0.005
T50.5 Appetite depressants	0.000	0.995	0.005
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.995	0.005
T50.1 Loop [high-ceiling] diuretics	0.000	0.995	0.005
T50.0 Mineralocorticoids and their antagonists	0.000	0.995	0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.995	0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.995	0.005
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.995	0.005
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.995	0.005
T36.0 Penicillins	0.000	0.995	0.005
Q89.2 Congenital malformations of other endocrine glands	0.005	0.995	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.995	0.005
Q85.9 Phakomatosis, unspecified	0.005	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
C78.0 Secondary malignant neoplasm of lung	0.005	0.995	0.000
Q83.1 Accessory breast	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q83 Congenital malformations of breast	0.005	0.995	0.000
K09 Cysts of oral region, not elsewhere classified	0.000	0.995	0.005
T50.4 Drugs affecting uric acid metabolism	0.000	0.995	0.005
C78.2 Secondary malignant neoplasm of pleura	0.005	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.995	0.005
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.995	0.005
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.005
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.005
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.995	0.005
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.995	0.005
T44.0 Anticholinesterase agents	0.000	0.995	0.005
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.995	0.005
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.995	0.005
T40.8 Lysergide [LSD]	0.000	0.995	0.005
T40.7 Cannabis (derivatives)	0.000	0.995	0.005
T40.3 Methadone	0.000	0.995	0.005
T40.1 Heroin	0.000	0.995	0.005
T40.0 Opium	0.000	0.995	0.005
T40.5 Cocaine	0.000	0.995	0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.995	0.005
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.995	0.004
K09.9 Cyst of oral region, unspecified	0.000	0.995	0.005
Q89.3 Situs inversus	0.004	0.995	0.000
Q85.1 Tuberous sclerosis	0.004	0.995	0.000
K09.2 Other cysts of jaw	0.000	0.995	0.004
C78.4 Secondary malignant neoplasm of small intestine	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.996	0.004
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.004	0.996	0.000
N86 Erosion and ectropion of cervix uteri	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
T36.8 Other systemic antibiotics	0.000	0.996	0.004
T36.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
T36.6 Rifamycins	0.000	0.996	0.004
T36.5 Aminoglycosides	0.000	0.996	0.004
T36.2 Chloramphenicol group	0.000	0.996	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.996	0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.996	0.004
Q89.9 Congenital malformation, unspecified	0.004	0.996	0.000
Q89.8 Other specified congenital malformations	0.004	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q89.4 Conjoined twins	0.004	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.996	0.000
Q89.0 Congenital malformations of spleen	0.004	0.996	0.000
O62 Abnormalities of forces of labour	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.004
T37.5 Antiviral drugs	0.000	0.996	0.004
T37.4 Anthelminthics	0.000	0.996	0.004
T37.3 Other antiprotozoal drugs	0.000	0.996	0.004
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.004
T37.1 Antimycobacterial drugs	0.000	0.996	0.004
T37.0 Sulphonamides	0.000	0.996	0.004
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.996	0.004
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.996	0.004
T48.5 Anti-common-cold drugs	0.000	0.996	0.004
T48.4 Expectorants	0.000	0.996	0.004
T48.3 Antitussives	0.000	0.996	0.004
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.996	0.004
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.996	0.004
T48.0 Oxytocic drugs	0.000	0.996	0.004
T49.9 Topical agent, unspecified	0.000	0.996	0.004
T49.8 Other topical agents	0.000	0.996	0.004
T49.7 Dental drugs, topically applied	0.000	0.996	0.004
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.004
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.004
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.004
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.004
T49.2 Local astringents and local detergents	0.000	0.996	0.004
T49.1 Antipruritics	0.000	0.996	0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.004
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.004	0.996	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.996	0.004
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
M50.1 Cervical disk disorder with radiculopathy	0.000	0.996	0.004
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
Q83.9 Congenital malformation of breast, unspecified	0.004	0.996	0.000
Q83.3 Accessory nipple	0.004	0.996	0.000
Q83.2 Absent nipple	0.004	0.996	0.000
Q83.0 Congenital absence of breast with absent nipple	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
E24 Cushing's syndrome	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.996	0.000
T36.3 Macrolides	0.000	0.996	0.003
T41.5 Therapeutic gases	0.000	0.996	0.003
T41.4 Anaesthetic, unspecified	0.000	0.996	0.003
T41.3 Local anaesthetics	0.000	0.996	0.003
T41.1 Intravenous anaesthetics	0.000	0.996	0.003
T41.0 Inhaled anaesthetics	0.000	0.996	0.003
Q21.0 Ventricular septal defect	0.003	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.003
T47.7 Emetics	0.000	0.996	0.003
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.003
T47.5 Digestants	0.000	0.996	0.003
T47.3 Saline and osmotic laxatives	0.000	0.996	0.003
T47.2 Stimulant laxatives	0.000	0.996	0.003
E20 Hypoparathyroidism	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.003
Q83.8 Other congenital malformations of breast	0.003	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.996	0.003
Y84.0 Cardiac catheterisation	0.000	0.996	0.004
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
E26 Hyperaldosteronism	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
T36.4 Tetracyclines	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
T46.7 Peripheral vasodilators	0.000	0.997	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
H01 Other inflammation of eyelid	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
O62.3 Precipitate labour	0.000	0.997	0.003
M84.8 Other disorders of continuity of bone	0.003	0.997	0.000
T47.4 Other laxatives	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.003
T38.7 Androgens and anabolic congeners	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
T38.5 Other oestrogens and progestogens	0.000	0.997	0.003
T38.4 Oral contraceptives	0.000	0.997	0.003
T38.2 Antithyroid drugs	0.000	0.997	0.003
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.003
T42.1 Iminostilbenes	0.000	0.997	0.003
Q03 Congenital hydrocephalus	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
O62.8 Other abnormalities of forces of labour	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.997	0.000
Q80.8 Other congenital ichthyosis	0.003	0.997	0.000
Q80.4 Harlequin foetus	0.003	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.997	0.000
Q80.2 Lamellar ichthyosis	0.003	0.997	0.000
Q80.1 X-linked ichthyosis	0.003	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.997	0.000
Q84.6 Other congenital malformations of nails	0.003	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.997	0.000
Q84.4 Congenital leukonychia	0.003	0.997	0.000
Q84.3 Anonychia	0.003	0.997	0.000
Q84.2 Other congenital malformations of hair	0.003	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.997	0.000
Q84.0 Congenital alopecia	0.003	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
Q36 Cleft lip	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
B08.1 Molluscum contagiosum	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.997	0.003
Q04.6 Congenital cerebral cysts	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
T45.5 Anticoagulants	0.000	0.997	0.003
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.003	0.997	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
O62.0 Primary inadequate contractions	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.000	0.997	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
O62.1 Secondary uterine inertia	0.000	0.997	0.003
R10.0 Acute abdomen	0.000	0.997	0.003
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.997	0.003
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q45.8 Other specified congenital malformations of digestive system	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.003	0.997	0.000
T42.3 Barbiturates	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
C78.1 Secondary malignant neoplasm of mediastinum	0.002	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
M84.9 Disorder of continuity of bone, unspecified	0.003	0.997	0.000
M84.3 Stress fracture, not elsewhere classified	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
R54 Senility	0.000	0.997	0.003
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
O12.0 Gestational oedema	0.000	0.997	0.003
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q04.9 Congenital malformation of brain, unspecified	0.002	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.997	0.000
Q04.5 Megalencephaly	0.002	0.997	0.000
Q04.4 Septo-optic dysplasia	0.002	0.997	0.000
Q04.3 Other reduction deformities of brain	0.002	0.997	0.000
Q04.2 Holoprosencephaly	0.002	0.997	0.000
Q04.1 Arhinencephaly	0.002	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.997	0.000
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.002	0.997	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.002	0.997	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.002	0.997	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.002	0.997	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.002	0.997	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.002	0.997	0.000
Q37.0 Cleft hard palate with bilateral cleft lip	0.002	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
K72.9 Hepatic failure, unspecified	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.997	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.997	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.997	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.997	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.997	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.997	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.997	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.997	0.000
Q15.0 Congenital glaucoma	0.002	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.997	0.000
E30.8 Other disorders of puberty	0.002	0.997	0.000
E30.1 Precocious puberty	0.002	0.997	0.000
E30.0 Delayed puberty	0.002	0.997	0.000
E32.9 Disease of thymus, unspecified	0.002	0.997	0.000
E32.8 Other diseases of thymus	0.002	0.997	0.000
E32.1 Abscess of thymus	0.002	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.997	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Z91.5 Personal history of self-harm	0.000	0.997	0.003
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.997	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.997	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.997	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
M84.2 Delayed union of fracture	0.002	0.997	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.002	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.002	0.997	0.000
Q18.7 Microcheilia	0.002	0.997	0.000
Q18.6 Macrocheilia	0.002	0.997	0.000
Q18.5 Microstomia	0.002	0.997	0.000
Q18.4 Macrostomia	0.002	0.997	0.000
Q18.3 Webbing of neck	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations