TreeWAS – Variant ID: rs13381277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.60 Fracture of lateral malleolus (closed)	0.000	0.945	0.055
S82.6 Fracture of lateral malleolus	0.000	0.965	0.035
S82.61 Fracture of lateral malleolus (open)	0.000	0.975	0.025
S82 Fracture of lower leg, including ankle	0.000	0.980	0.020
S82.5 Fracture of medial malleolus	0.000	0.982	0.017
S82.3 Fracture of lower end of tibia	0.000	0.983	0.017
S82.4 Fracture of fibula alone	0.000	0.983	0.017
S82.1 Fracture of upper end of tibia	0.000	0.984	0.016
S82.30 Fracture of lower end of tibia (closed)	0.000	0.984	0.016
S82.50 Fracture of medial malleolus (closed)	0.000	0.984	0.016
O70.0 First degree perineal laceration during delivery	0.015	0.985	0.000
S82.9 Fracture of lower leg, part unspecified	0.000	0.985	0.015
S82.40 Fracture of fibula alone (closed)	0.000	0.986	0.014
S82.0 Fracture of patella	0.000	0.986	0.014
S82.7 Multiple fractures of lower leg	0.000	0.987	0.013
S82.51 Fracture of medial malleolus (open)	0.000	0.987	0.013
S82.10 Fracture of upper end of tibia (closed)	0.000	0.988	0.012
S82.41 Fracture of fibula alone (open)	0.000	0.988	0.012
S82.11 Fracture of upper end of tibia (open)	0.000	0.988	0.011
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.989	0.011
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.989	0.011
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.989	0.011
S82.2 Fracture of shaft of tibia	0.000	0.990	0.010
S82.31 Fracture of lower end of tibia (open)	0.000	0.990	0.010
S82.01 Fracture of patella (open)	0.000	0.990	0.010
S82.71 Multiple fractures of lower leg (open)	0.000	0.990	0.010
S82.8 Fractures of other parts of lower leg	0.000	0.990	0.010
Z96.0 Presence of urogenital implants	0.009	0.991	0.000
S82.00 Fracture of patella (closed)	0.000	0.991	0.009
S82.70 Multiple fractures of lower leg (closed)	0.000	0.992	0.008
S80-S89 Injuries to the knee and lower leg	0.000	0.992	0.008
S80 Superficial injury of lower leg	0.000	0.993	0.007
S82.86 Maisonneuve's fracture	0.000	0.993	0.007
S82.81 Fractures of other parts of lower leg (open)	0.000	0.993	0.007
M17.9 Gonarthrosis, unspecified	0.000	0.993	0.007
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.993	0.007
J84 Other interstitial pulmonary diseases	0.000	0.993	0.007
Z96.6 Presence of orthopaedic joint implants	0.000	0.993	0.007
D41.4 Bladder	0.000	0.993	0.007
S81 Open wound of lower leg	0.000	0.993	0.007
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.993	0.007
S80.9 Superficial injury of lower leg, unspecified	0.000	0.994	0.006
S80.0 Contusion of knee	0.000	0.994	0.006
S82.21 Fracture of shaft of tibia (open)	0.000	0.994	0.006
S88 Traumatic amputation of lower leg	0.000	0.994	0.006
S87 Crushing injury of lower leg	0.000	0.994	0.006
S85 Injury of blood vessels at lower leg level	0.000	0.994	0.006
S84 Injury of nerves at lower leg level	0.000	0.994	0.006
S82.20 Fracture of shaft of tibia (closed)	0.000	0.994	0.006
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.994	0.006
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.994	0.006
F20.9 Schizophrenia, unspecified	0.000	0.994	0.006
J81 Pulmonary oedema	0.000	0.994	0.006
S81.9 Open wound of lower leg, part unspecified	0.000	0.994	0.006
S89 Other and unspecified injuries of lower leg	0.000	0.994	0.005
S81.8 Open wound of other parts of lower leg	0.000	0.994	0.005
S80.7 Multiple superficial injuries of lower leg	0.000	0.995	0.005
J80 Adult respiratory distress syndrome	0.000	0.995	0.005
J84.8 Other specified interstitial pulmonary diseases	0.000	0.995	0.005
J84.0 Alveolar and parietoalveolar conditions	0.000	0.995	0.005
S81.7 Multiple open wounds of lower leg	0.000	0.995	0.005
K05.3 Chronic periodontitis	0.005	0.995	0.000
S86 Injury of muscle and tendon at lower leg level	0.000	0.995	0.005
J92.9 Pleural plaque without asbestos	0.000	0.995	0.005
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.995	0.005
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.995	0.004
S84.8 Injury of other nerves at lower leg level	0.000	0.995	0.004
S84.7 Injury of multiple nerves at lower leg level	0.000	0.995	0.004
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.995	0.004
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.995	0.004
S84.0 Injury of tibial nerve at lower leg level	0.000	0.995	0.004
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.995	0.004
S85.8 Injury of other blood vessels at lower leg level	0.000	0.995	0.004
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.995	0.004
S85.5 Injury of popliteal vein	0.000	0.995	0.004
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.995	0.004
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.995	0.004
S85.2 Injury of peroneal artery	0.000	0.995	0.004
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.995	0.004
S85.0 Injury of popliteal artery	0.000	0.995	0.004
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.995	0.004
S87.0 Crushing injury of knee	0.000	0.995	0.004
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.995	0.004
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.995	0.004
S88.0 Traumatic amputation at knee level	0.000	0.995	0.004
E87.6 Hypokalaemia	0.000	0.995	0.005
S89.9 Unspecified injury of lower leg	0.000	0.996	0.004
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.996	0.004
S81.0 Open wound of knee	0.000	0.996	0.004
M65.34 Trigger finger-Hand	0.000	0.996	0.004
S89.7 Multiple injuries of lower leg	0.000	0.996	0.004
S89.1 Other specified injuries of lower leg	0.000	0.996	0.004
S89.0 Multiple injuries of lower leg	0.000	0.996	0.004
I12.0 Hypertensive renal disease with renal failure	0.000	0.996	0.004
S80.8 Other superficial injuries of lower leg	0.000	0.996	0.004
F20 Schizophrenia	0.000	0.996	0.004
D37.7 Other digestive organs	0.000	0.996	0.004
D37.5 Rectum	0.000	0.996	0.004
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.996	0.004
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
K05 Gingivitis and periodontal diseases	0.004	0.996	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.996	0.004
S86.0 Injury of Achilles tendon	0.000	0.996	0.003
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.996	0.003
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.996	0.003
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.996	0.003
F20.0 Paranoid schizophrenia	0.000	0.996	0.004
K04.7 Periapical abscess without sinus	0.004	0.996	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.996	0.003
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.996	0.003
K08.8 Other specified disorders of teeth and supporting structures	0.004	0.996	0.000
S89.8 Other specified injuries of lower leg	0.000	0.996	0.003
I12 Hypertensive renal disease	0.000	0.996	0.003
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.996	0.003
S83.7 Injury to multiple structures of knee	0.000	0.997	0.003
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.997	0.003
S83.3 Tear of articular cartilage of knee, current	0.000	0.997	0.003
S83.1 Dislocation of knee	0.000	0.997	0.003
S83.0 Dislocation of patella	0.000	0.997	0.003
M47.86 Other spondylosis (Lumbar region)	0.000	0.997	0.003
D37.4 Colon	0.000	0.997	0.003
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.997	0.003
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.997	0.003
K05.6 Periodontal disease, unspecified	0.003	0.997	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.997	0.003
D37.0 Lip, oral cavity and pharynx	0.000	0.997	0.003
F20.8 Other schizophrenia	0.000	0.997	0.003
F20.6 Simple schizophrenia	0.000	0.997	0.003
F20.5 Residual schizophrenia	0.000	0.997	0.003
F20.4 Postschizophrenic depression	0.000	0.997	0.003
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.003
F20.2 Catatonic schizophrenia	0.000	0.997	0.003
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.003
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.003
M47.8 Other spondylosis	0.000	0.997	0.003
K01.1 Impacted teeth	0.003	0.997	0.000
K08 Other disorders of teeth and supporting structures	0.003	0.997	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.997	0.003
D37.6 Liver, gallbladder and bile ducts	0.000	0.997	0.003
D37.3 Appendix	0.000	0.997	0.003
D37.2 Small intestine	0.000	0.997	0.003
K05.2 Acute periodontitis	0.003	0.997	0.000
K05.5 Other periodontal diseases	0.003	0.997	0.000
K05.4 Periodontosis	0.003	0.997	0.000
K05.0 Acute gingivitis	0.003	0.997	0.000
R09.1 Pleurisy	0.003	0.997	0.000
D41.9 Urinary organ, unspecified	0.000	0.997	0.003
D41.7 Other urinary organs	0.000	0.997	0.003
D41.3 Urethra	0.000	0.997	0.003
D41.2 Ureter	0.000	0.997	0.003
D41.1 Renal pelvis	0.000	0.997	0.003
S86.00 Unspecified injury of Achilles tendon	0.000	0.997	0.003
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
D37.1 Stomach	0.000	0.997	0.003
K05.1 Chronic gingivitis	0.003	0.997	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.997	0.003
K01 Embedded and impacted teeth	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.003	0.997	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.997	0.003
D37.9 Digestive organ, unspecified	0.000	0.997	0.003
K08.2 Atrophy of edentulous alveolar ridge	0.003	0.997	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.997	0.003
I49.3 Ventricular premature depolarisation	0.000	0.997	0.003
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.003	0.997	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.997	0.003
J92 Pleural plaque	0.000	0.997	0.003
M17 Gonarthrosis [arthrosis of knee]	0.000	0.997	0.003
N18 Chronic renal failure	0.000	0.997	0.003
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.997	0.000
K04 Diseases of pulp and periapical tissues	0.003	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.997	0.002
M47.84 Other spondylosis (Thoracic region)	0.000	0.997	0.002
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.997	0.002
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.997	0.002
K08.9 Disorder of teeth and supporting structures, unspecified	0.002	0.997	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.002	0.997	0.000
M65.3 Trigger finger	0.000	0.997	0.002
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
K05.22 Aggressive periodontitis, generalized	0.002	0.998	0.000
C54.1 Endometrium	0.000	0.998	0.002
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.998	0.002
D41.0 Kidney	0.000	0.998	0.002
D50.9 Iron deficiency anaemia, unspecified	0.000	0.998	0.002
K00 Disorders of tooth development and eruption	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.998	0.002
K00.9 Disorder of tooth development, unspecified	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
N18.0 End-stage renal disease	0.000	0.998	0.002
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
K01.0 Embedded teeth	0.002	0.998	0.000
K08.3 Retained dental root	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.998	0.002
K12.0 Recurrent oral aphthae	0.002	0.998	0.000
K12 Stomatitis and related lesions	0.002	0.998	0.000
K07 Dentofacial anomalies [including malocclusion]	0.002	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
K04.0 Pulpitis	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.002	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
D45 Polycythaemia vera	0.000	0.998	0.002
K03 Other diseases of hard tissues of teeth	0.002	0.998	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.998	0.002
Z03.4 Observation for suspected myocardial infarction	0.002	0.998	0.000
K14 Diseases of tongue	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.000	0.998	0.002
N18.1 Chronic kidney disease, stage 1	0.000	0.998	0.002
K04.4 Acute apical periodontitis of pulpal origin	0.002	0.998	0.000
K04.3 Abnormal hard tissue formation in pulp	0.002	0.998	0.000
K04.2 Pulp degeneration	0.002	0.998	0.000
K04.1 Necrosis of pulp	0.002	0.998	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.002	0.998	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.998	0.002
K04.8 Radicular cyst	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
M65.39 Trigger finger-Site unspec	0.000	0.998	0.002
M65.38 Trigger finger-Other	0.000	0.998	0.002
M65.37 Trigger finger-Ankle/foot	0.000	0.998	0.002
M65.36 Trigger finger-Lower leg	0.000	0.998	0.002
M65.35 Trigger finger-Pelvic/thigh	0.000	0.998	0.002
M65.33 Trigger finger-Forearm	0.000	0.998	0.002
M65.32 Trigger finger-Upper arm	0.000	0.998	0.002
M65.31 Trigger finger-Shldr region	0.000	0.998	0.002
M65.30 Trigger finger-Mult sites	0.000	0.998	0.002
K09 Cysts of oral region, not elsewhere classified	0.002	0.998	0.000
H53.4 Visual field defects	0.000	0.998	0.002
K07.3 Anomalies of tooth position	0.002	0.998	0.000
M17.5 Other secondary gonarthrosis	0.000	0.998	0.002
Z91.7 Personal history of female genital mutilation	0.000	0.998	0.002
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.000	0.998	0.002
Z91.3 Personal history of unhealthy sleep-wake schedule	0.000	0.998	0.002
Z91.2 Personal history of poor personal hygiene	0.000	0.998	0.002
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
M47.82 Other spondylosis (Cervical region)	0.000	0.998	0.002
K00.8 Other disorders of tooth development	0.002	0.998	0.000
K00.7 Teething syndrome	0.002	0.998	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.002	0.998	0.000
K00.4 Disturbances in tooth formation	0.002	0.998	0.000
K00.3 Mottled teeth	0.002	0.998	0.000
K00.2 Abnormalities of size and form of teeth	0.002	0.998	0.000
K00.1 Supernumerary teeth	0.002	0.998	0.000
K00.0 Anodontia	0.002	0.998	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.000	0.998	0.002
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.998	0.002
D50 Iron deficiency anaemia	0.000	0.998	0.002
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.998	0.002
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.998	0.002
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.998	0.002
D46 Myelodysplastic syndromes	0.000	0.998	0.002
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.002	0.998	0.000
K07.9 Dentofacial anomaly, unspecified	0.002	0.998	0.000
K07.8 Other dentofacial anomalies	0.002	0.998	0.000
K07.5 Dentofacial functional abnormalities	0.002	0.998	0.000
K07.2 Anomalies of dental arch relationship	0.002	0.998	0.000
K07.0 Major anomalies of jaw size	0.002	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.998	0.000
M54.9 Dorsalgia, unspecified	0.000	0.998	0.002
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.998	0.002
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.002	0.998	0.000
K06.1 Gingival enlargement	0.002	0.998	0.000
K06.0 Gingival recession	0.002	0.998	0.000
K07.4 Malocclusion, unspecified	0.002	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.002	0.998	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
O70.3 Fourth degree perineal laceration during delivery	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.998	0.002
K03.9 Disease of hard tissues of teeth, unspecified	0.002	0.998	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.002	0.998	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.002	0.998	0.000
K03.6 Deposits [accretions] on teeth	0.002	0.998	0.000
K03.5 Ankylosis of teeth	0.002	0.998	0.000
K03.4 Hypercementosis	0.002	0.998	0.000
K03.3 Pathological resorption of teeth	0.002	0.998	0.000
K03.2 Erosion of teeth	0.002	0.998	0.000
K03.1 Abrasion of teeth	0.002	0.998	0.000
K03.0 Excessive attrition of teeth	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
K14.5 Plicated tongue	0.002	0.998	0.000
K14.4 Atrophy of tongue papillae	0.002	0.998	0.000
K14.3 Hypertrophy of tongue papillae	0.002	0.998	0.000
K14.2 Median rhomboid glossitis	0.002	0.998	0.000
K14.1 Geographic tongue	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.998	0.002
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
Z37.0 Single live birth	0.002	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
K10 Other diseases of jaws	0.001	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.000	0.998	0.002
D38.5 Other respiratory organs	0.000	0.998	0.002
D38.4 Thymus	0.000	0.998	0.002
D38.3 Mediastinum	0.000	0.998	0.002
D38.2 Pleura	0.000	0.998	0.002
D38.0 Larynx	0.000	0.998	0.002
D42.9 Meninges, unspecified	0.000	0.998	0.001
D42.1 Spinal meninges	0.000	0.998	0.001
D42.0 Cerebral meninges	0.000	0.998	0.001
D50.1 Sideropenic dysphagia	0.000	0.998	0.002
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
H52.0 Hypermetropia	0.000	0.998	0.002
Z91.6 Personal history of other physical trauma	0.000	0.998	0.002
I44.7 Left bundle-branch block, unspecified	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.998	0.002
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.998	0.002
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.001
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.001
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.001
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.001
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.001
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.001
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.001
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.998	0.001
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.998	0.002
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
D39.9 Female genital organ, unspecified	0.000	0.998	0.001
D39.7 Other female genital organs	0.000	0.998	0.001
D39.2 Placenta	0.000	0.998	0.001
D39.0 Uterus	0.000	0.998	0.001
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
D43.9 Central nervous system, unspecified	0.000	0.998	0.001
D43.7 Other parts of central nervous system	0.000	0.998	0.001
D43.4 Spinal cord	0.000	0.998	0.001
D43.3 Cranial nerves	0.000	0.998	0.001
D43.1 Brain, infratentorial	0.000	0.998	0.001
D43.0 Brain, supratentorial	0.000	0.998	0.001
G93.0 Cerebral cysts	0.000	0.998	0.002
K09.0 Developmental odontogenic cysts	0.001	0.998	0.000
M17.1 Other primary gonarthrosis	0.000	0.998	0.002
O70.9 Perineal laceration during delivery, unspecified	0.001	0.998	0.000
K02 Dental caries	0.002	0.998	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.998	0.002
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.998	0.002
G93 Other disorders of brain	0.000	0.998	0.002
M47 Spondylosis	0.000	0.998	0.002
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.998	0.001
G93.2 Benign intracranial hypertension	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
F25 Schizoaffective disorders	0.000	0.998	0.001
F23 Acute and transient psychotic disorders	0.000	0.998	0.001
D44.9 Endocrine gland, unspecified	0.000	0.998	0.001
D44.8 Pluriglandular involvement	0.000	0.998	0.001
D44.7 Aortic body and other paraganglia	0.000	0.998	0.001
D44.6 Carotid body	0.000	0.998	0.001
D44.5 Pineal gland	0.000	0.998	0.001
D44.4 Craniopharyngeal duct	0.000	0.998	0.001
D44.3 Pituitary gland	0.000	0.998	0.001
D44.2 Parathyroid gland	0.000	0.998	0.001
D44.0 Thyroid gland	0.000	0.998	0.001
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.001
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.001
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.001
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
D39.1 Ovary	0.000	0.998	0.001
K10.9 Disease of jaws, unspecified	0.001	0.998	0.000
K10.3 Alveolitis of jaws	0.001	0.998	0.000
K10.1 Giant cell granuloma, central	0.001	0.998	0.000
K10.0 Developmental disorders of jaws	0.001	0.998	0.000
K11.3 Abscess of salivary gland	0.001	0.998	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.998	0.001
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.002
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.001	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.001	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.998	0.001
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.001
K07.6 Temporomandibular joint disorders	0.001	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.001	0.998	0.000
K12.1 Other forms of stomatitis	0.001	0.998	0.000
N13.6 Pyonephrosis	0.001	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.998	0.001
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.999	0.001
D40.9 Male genital organ, unspecified	0.000	0.999	0.001
D40.7 Other male genital organs	0.000	0.999	0.001
D43.2 Brain, unspecified	0.000	0.999	0.001
G93.6 Cerebral oedema	0.000	0.999	0.001
C50.2 Upper-inner quadrant of breast	0.000	0.999	0.001
D47.2 Monoclonal gammopathy	0.000	0.999	0.001
K04.6 Periapical abscess with sinus	0.001	0.999	0.000
K09.2 Other cysts of jaw	0.001	0.999	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.999	0.001
F28 Other nonorganic psychotic disorders	0.000	0.999	0.001
F24 Induced delusional disorder	0.000	0.999	0.001
F21 Schizotypal disorder	0.000	0.999	0.001
K11 Diseases of salivary glands	0.001	0.999	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.999	0.001
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.999	0.001
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.999	0.001
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.999	0.001
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.999	0.001
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.999	0.001
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.999	0.001
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.999	0.001
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.999	0.001
D44.1 Adrenal gland	0.001	0.999	0.001
K02.5 Caries with pulp exposure	0.001	0.999	0.000
K02.4 Odontoclasia	0.001	0.999	0.000
K02.3 Arrested dental caries	0.001	0.999	0.000
K02.2 Caries of cementum	0.001	0.999	0.000
K02.1 Caries of dentin	0.001	0.999	0.000
K02.0 Caries limited to enamel	0.001	0.999	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.999	0.001
O70.2 Third degree perineal laceration during delivery	0.001	0.999	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.999	0.001
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.999	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.999	0.001
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.999	0.001
D48.7 Other specified sites	0.000	0.999	0.001
D48.4 Peritoneum	0.000	0.999	0.001
D48.3 Retroperitoneum	0.000	0.999	0.001
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.999	0.001
F23.8 Other acute and transient psychotic disorders	0.000	0.999	0.001
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.999	0.001
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.999	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.999	0.001
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.999	0.001
F25.8 Other schizoaffective disorders	0.000	0.999	0.001
F25.2 Schizoaffective disorder, mixed type	0.000	0.999	0.001
F25.1 Schizoaffective disorder, depressive type	0.000	0.999	0.001
F25.0 Schizoaffective disorder, manic type	0.000	0.999	0.001
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
G93.7 Reye's syndrome	0.000	0.999	0.001
G93.5 Compression of brain	0.000	0.999	0.001
K10.2 Inflammatory conditions of jaws	0.001	0.999	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.999	0.001
T83.3 Mechanical complication of intra-uterine contraceptive device	0.001	0.999	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.999	0.001
I49.8 Other specified cardiac arrhythmias	0.000	0.999	0.001
N13.9 Obstructive and reflux uropathy, unspecified	0.001	0.999	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.001	0.999	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.999	0.001
O02.1 Missed abortion	0.000	0.999	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.001	0.999	0.000
H43.8 Other disorders of vitreous body	0.000	0.999	0.001
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.999	0.001
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.999	0.001
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.999	0.001
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.999	0.001
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.999	0.001
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.999	0.001
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.999	0.001
M54.22 Cervicalgia (Cervical region)	0.000	0.999	0.001
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.999	0.001
D48.5 Skin	0.000	0.999	0.001
D48.0 Bone and articular cartilage	0.000	0.999	0.001
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.999	0.001
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.999	0.001
M54.3 Sciatica	0.000	0.999	0.001
R49.0 Dysphonia	0.000	0.999	0.001
D40.0 Prostate	0.000	0.999	0.001
D47.1 Chronic myeloproliferative disease	0.000	0.999	0.001
K02.8 Other dental caries	0.001	0.999	0.000
F22 Persistent delusional disorders	0.000	0.999	0.001
D40.1 Testis	0.001	0.999	0.001
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.001	0.999	0.000
I46.9 Cardiac arrest, unspecified	0.001	0.999	0.000
K11.7 Disturbances of salivary secretion	0.001	0.999	0.000
K11.4 Fistula of salivary gland	0.001	0.999	0.000
K11.0 Atrophy of salivary gland	0.001	0.999	0.000
K22.8 Other specified diseases of oesophagus	0.001	0.999	0.000
M54.2 Cervicalgia	0.000	0.999	0.001
N13.4 Hydroureter	0.001	0.999	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.999	0.001
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.999	0.001
O72 Postpartum haemorrhage	0.001	0.999	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.999	0.001
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.999	0.001
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.999	0.001
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.999	0.001
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.999	0.001
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.999	0.001
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.999	0.001
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations