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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13437000
log Bayes Factor = 10.4886
Chromosome 6   position 33,105,064  (GRCh37) Explore rs13437000 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.007 0.993
E00-E07 Disorders of thyroid gland
0.000 0.015 0.985
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.016 0.984
E10.1 With ketoacidosis
0.000 0.020 0.980
E16 Other disorders of pancreatic internal secretion
0.000 0.022 0.978
E16.2 Hypoglycaemia, unspecified
0.000 0.025 0.975
E04 Other non-toxic goitre
0.000 0.029 0.971
E10.5 With peripheral circulatory complications
0.000 0.068 0.932
E06 Thyroiditis
0.000 0.069 0.931
E04.2 Non-toxic multinodular goitre
0.000 0.076 0.924
E11 Non-insulin-dependent diabetes mellitus
0.000 0.080 0.920
E50-E64 Other nutritional deficiencies
0.000 0.083 0.917
E04.1 Non-toxic single thyroid nodule
0.000 0.084 0.916
E10.2 With renal complications
0.000 0.094 0.906
E06.3 Autoimmune thyroiditis
0.000 0.113 0.887
E03 Other hypothyroidism
0.000 0.133 0.867
E11.3 With ophthalmic complications
0.000 0.135 0.865
E10.6 With other specified complications
0.000 0.146 0.854
E11.4 With neurological complications
0.000 0.146 0.854
E10.4 With neurological complications
0.000 0.155 0.845
E53 Deficiency of other B group vitamins
0.000 0.161 0.839
E55 Vitamin D deficiency
0.000 0.169 0.831
E11.1 With ketoacidosis
0.000 0.175 0.825
E03.9 Hypothyroidism, unspecified
0.000 0.188 0.812
E53.8 Deficiency of other specified B group vitamins
0.000 0.201 0.799
E14 Unspecified diabetes mellitus
0.000 0.225 0.775
E55.9 Vitamin D deficiency, unspecified
0.000 0.229 0.771
E04.0 Non-toxic diffuse goitre
0.000 0.237 0.763
E10.0 With coma
0.000 0.268 0.732
E10.8 With unspecified complications
0.000 0.269 0.731
E10.7 With multiple complications
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E14.3 With ophthalmic complications
0.000 0.292 0.708
E06.9 Thyroiditis, unspecified
0.000 0.294 0.706
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.294 0.706
E00 Congenital iodine-deficiency syndrome
0.000 0.294 0.706
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.294 0.706
E15 Nondiabetic hypoglycaemic coma
0.000 0.294 0.705
E11.6 With other specified complications
0.000 0.295 0.705
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.299 0.701
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.299 0.701
E16.4 Abnormal secretion of gastrin
0.000 0.299 0.701
E16.3 Increased secretion of glucagon
0.000 0.299 0.701
E04.8 Other specified non-toxic goitre
0.000 0.304 0.696
E06.5 Other chronic thyroiditis
0.000 0.332 0.668
E06.4 Drug-induced thyroiditis
0.000 0.332 0.668
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.332 0.668
E06.1 Subacute thyroiditis
0.000 0.332 0.668
E06.0 Acute thyroiditis
0.000 0.332 0.668
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.334 0.666
E11.7 With multiple complications
0.000 0.340 0.660
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.343 0.657
E63 Other nutritional deficiencies
0.000 0.343 0.657
E56 Other vitamin deficiencies
0.000 0.343 0.657
E50 Vitamin A deficiency
0.000 0.343 0.657
E60 Dietary zinc deficiency
0.000 0.343 0.657
E59 Dietary selenium deficiency
0.000 0.343 0.657
E58 Dietary calcium deficiency
0.000 0.343 0.657
E54 Ascorbic acid deficiency
0.000 0.343 0.657
E52 Niacin deficiency [pellagra]
0.000 0.343 0.657
E11.0 With coma
0.000 0.350 0.650
E11.8 With unspecified complications
0.000 0.369 0.631
E51 Thiamine deficiency
0.000 0.372 0.628
E16.1 Other hypoglycaemia
0.000 0.372 0.627
E03.5 Myxoedema coma
0.000 0.378 0.622
E03.4 Atrophy of thyroid (acquired)
0.000 0.378 0.622
E03.3 Postinfectious hypothyroidism
0.000 0.378 0.622
E03.1 Congenital hypothyroidism without goitre
0.000 0.378 0.622
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.378 0.622
E53.1 Pyridoxine deficiency
0.000 0.398 0.601
E53.0 Riboflavin deficiency
0.000 0.398 0.601
E55.0 Rickets, active
0.000 0.404 0.596
E11.2 With renal complications
0.000 0.405 0.595
E04.9 Non-toxic goitre, unspecified
0.000 0.418 0.582
E14.1 With ketoacidosis
0.000 0.442 0.558
E14.7 With multiple complications
0.000 0.444 0.555
E14.6 With other specified complications
0.000 0.444 0.555
E14.5 With peripheral circulatory complications
0.000 0.444 0.555
E14.2 Withrenal complications
0.000 0.444 0.555
E14.0 With coma
0.000 0.444 0.555
E65-E68 Obesity and other hyperalimentation
0.000 0.448 0.552
E20-E35 Disorders of other endocrine glands
0.000 0.449 0.551
E14.8 With unspecified complications
0.000 0.458 0.542
E14.4 With neurological complications
0.000 0.465 0.535
E13 Other specified diabetes mellitus
0.001 0.478 0.521
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E53.9 Vitamin B deficiency, unspecified
0.000 0.487 0.512
E20 Hypoparathyroidism
0.000 0.492 0.508
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.494 0.506
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.494 0.506
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.494 0.506
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.494 0.506
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.494 0.506
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.494 0.506
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.494 0.506
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.494 0.506
E40-E46 Malnutrition
0.001 0.497 0.503
E27 Other disorders of adrenal gland
0.000 0.512 0.488
E20.9 Hypoparathyroidism, unspecified
0.000 0.522 0.478
E27.1 Primary adrenocortical insufficiency
0.000 0.526 0.473
E50.9 Vitamin A deficiency, unspecified
0.000 0.529 0.471
E50.8 Other manifestations of vitamin A deficiency
0.000 0.529 0.471
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.529 0.471
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.529 0.471
E50.5 Vitamin A deficiency with night blindness
0.000 0.529 0.471
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.529 0.471
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.529 0.471
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.529 0.471
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.529 0.471
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.529 0.471
E56.9 Vitamin deficiency, unspecified
0.000 0.529 0.471
E56.8 Deficiency of other vitamins
0.000 0.529 0.471
E56.1 Deficiency of vitamin K
0.000 0.529 0.471
E56.0 Deficiency of vitamin E
0.000 0.529 0.471
E63.9 Nutritional deficiency, unspecified
0.000 0.529 0.471
E63.8 Other specified nutritional deficiencies
0.000 0.529 0.471
E63.1 Imbalance of constituents of food intake
0.000 0.529 0.471
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.529 0.471
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.529 0.471
E64.8 Sequelae of other nutritional deficiencies
0.000 0.529 0.471
E64.3 Sequelae of rickets
0.000 0.529 0.471
E64.2 Sequelae of vitamin C deficiency
0.000 0.529 0.471
E64.1 Sequelae of vitamin A deficiency
0.000 0.529 0.471
E64.0 Sequelae of protein-energy malnutrition
0.000 0.529 0.471
E07 Other disorders of thyroid
0.000 0.538 0.462
E51.9 Thiamine deficiency, unspecified
0.000 0.550 0.450
E51.8 Other manifestations of thiamine deficiency
0.000 0.550 0.450
E51.1 Beriberi
0.000 0.550 0.450
E65 Localised adiposity
0.000 0.570 0.430
E51.2 Wernicke's encephalopathy
0.000 0.579 0.421
E61 Deficiency of other nutrient elements
0.000 0.581 0.418
E03.8 Other specified hypothyroidism
0.000 0.584 0.416
E67 Other hyperalimentation
0.000 0.604 0.396
E68 Sequelae of hyperalimentation
0.000 0.604 0.396
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.605 0.395
E32 Diseases of thymus
0.000 0.605 0.395
E31 Polyglandular dysfunction
0.000 0.605 0.395
E30 Disorders of puberty, not elsewhere classified
0.000 0.605 0.395
E25 Adrenogenital disorders
0.000 0.605 0.395
E22 Hyperfunction of pituitary gland
0.000 0.617 0.383
E13.8 With unspecified complications
0.001 0.626 0.374
E13.7 With multiple complications
0.001 0.626 0.374
E13.6 With other specified complications
0.001 0.626 0.374
E13.5 With peripheral circulatory complications
0.001 0.626 0.374
E13.4 With neurological complications
0.001 0.626 0.374
E13.3 With ophthalmic complications
0.001 0.626 0.374
E13.2 With renal complications
0.001 0.626 0.374
E13.1 With ketoacidosis
0.001 0.626 0.374
E13.0 With coma
0.001 0.626 0.374
E28 Ovarian dysfunction
0.000 0.633 0.367
E26 Hyperaldosteronism
0.000 0.634 0.366
E20.8 Other hypoparathyroidism
0.000 0.636 0.364
E20.1 Pseudohypoparathyroidism
0.000 0.636 0.364
E20.0 Idiopathic hypoparathyroidism
0.000 0.636 0.364
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.639 0.360
E45 Retarded development following protein-energy malnutrition
0.001 0.639 0.360
E43 Unspecified severe protein-energy malnutrition
0.001 0.639 0.360
E42 Marasmic kwashiorkor
0.001 0.639 0.360
E41 Nutritional marasmus
0.001 0.639 0.360
E40 Kwashiorkor
0.001 0.639 0.360
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.648 0.352
E27.5 Adrenomedullary hyperfunction
0.000 0.650 0.350
E27.0 Other adrenocortical overactivity
0.000 0.650 0.350
E27.2 Addisonian crisis
0.000 0.657 0.343
E27.9 Disorder of adrenal gland, unspecified
0.000 0.659 0.340
E29 Testicular dysfunction
0.000 0.664 0.336
E34 Other endocrine disorders
0.000 0.664 0.335
E07.1 Dyshormogenetic goitre
0.000 0.669 0.331
E07.0 Hypersecretion of calcitonin
0.000 0.669 0.331
E14.9 Without complications
0.000 0.678 0.322
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.685 0.315
E07.8 Other specified disorders of thyroid
0.000 0.698 0.302
E61.9 Deficiency of nutrient element, unspecified
0.000 0.700 0.300
E61.8 Deficiency of other specified nutrient elements
0.000 0.700 0.300
E61.7 Deficiency of multiple nutrient elements
0.000 0.700 0.300
E61.6 Vanadium deficiency
0.000 0.700 0.300
E61.5 Molybdenum deficiency
0.000 0.700 0.300
E61.4 Chromium deficiency
0.000 0.700 0.300
E61.3 Manganese deficiency
0.000 0.700 0.300
E61.0 Copper deficiency
0.000 0.700 0.300
E67.8 Other specified hyperalimentation
0.000 0.716 0.284
E67.3 Hypervitaminosis D
0.000 0.716 0.284
E67.2 Megavitamin-B6 syndrome
0.000 0.716 0.284
E67.1 Hypercarotenaemia
0.000 0.716 0.284
E67.0 Hypervitaminosis A
0.000 0.716 0.284
E28.3 Primary ovarian failure
0.000 0.716 0.284
E25.9 Adrenogenital disorder, unspecified
0.000 0.717 0.283
E25.8 Other adrenogenital disorders
0.000 0.717 0.283
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.717 0.283
E30.9 Disorder of puberty, unspecified
0.000 0.717 0.283
E30.8 Other disorders of puberty
0.000 0.717 0.283
E30.1 Precocious puberty
0.000 0.717 0.283
E30.0 Delayed puberty
0.000 0.717 0.283
E31.9 Polyglandular dysfunction, unspecified
0.000 0.717 0.283
E31.8 Other polyglandular dysfunction
0.000 0.717 0.283
E31.1 Polyglandular hyperfunction
0.000 0.717 0.283
E31.0 Autoimmune polyglandular failure
0.000 0.717 0.283
E32.9 Disease of thymus, unspecified
0.000 0.717 0.283
E32.8 Other diseases of thymus
0.000 0.717 0.283
E32.1 Abscess of thymus
0.000 0.717 0.283
E32.0 Persistent hyperplasia of thymus
0.000 0.717 0.283
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.717 0.283
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.717 0.283
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.717 0.283
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.718 0.282
E24 Cushing's syndrome
0.000 0.725 0.275
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.725 0.275
E22.8 Other hyperfunction of pituitary gland
0.000 0.725 0.275
E26.0 Primary hyperaldosteronism
0.000 0.734 0.266
E28.9 Ovarian dysfunction, unspecified
0.000 0.736 0.263
E28.8 Other ovarian dysfunction
0.000 0.736 0.263
E28.1 Androgen excess
0.000 0.736 0.263
E28.0 Oestrogen excess
0.000 0.736 0.263
E26.8 Other hyperaldosteronism
0.000 0.737 0.263
E26.1 Secondary hyperaldosteronism
0.000 0.737 0.263
E23 Hypofunction and other disorders of pituitary gland
0.000 0.738 0.262
E44.1 Mild protein-energy malnutrition
0.001 0.741 0.258
E44.0 Moderate protein-energy malnutrition
0.001 0.741 0.258
E11.5 With peripheral circulatory complications
0.001 0.746 0.253
E61.2 Magnesium deficiency
0.001 0.749 0.251
E22.0 Acromegaly and pituitary gigantism
0.000 0.753 0.247
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.753 0.247
E34.0 Carcinoid syndrome
0.000 0.757 0.243
E29.9 Testicular dysfunction, unspecified
0.000 0.759 0.241
E29.8 Other testicular dysfunction
0.000 0.759 0.241
E29.0 Testicular hyperfunction
0.000 0.759 0.241
E34.5 Androgen resistance syndrome
0.000 0.759 0.241
E34.4 Constitutional tall stature
0.000 0.759 0.241
E34.3 Short stature, not elsewhere classified
0.000 0.759 0.241
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.759 0.241
E34.1 Other hypersecretion of intestinal hormones
0.000 0.759 0.241
E27.8 Other specified disorders of adrenal gland
0.000 0.764 0.235
E22.1 Hyperprolactinaemia
0.000 0.768 0.232
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.768 0.232
E26.9 Hyperaldosteronism, unspecified
0.000 0.770 0.230
E23.6 Other disorders of pituitary gland
0.000 0.784 0.216
E34.8 Other specified endocrine disorders
0.000 0.785 0.215
E34.9 Endocrine disorder, unspecified
0.000 0.789 0.211
E28.2 Polycystic ovarian syndrome
0.000 0.797 0.203
E24.8 Other Cushing's syndrome
0.000 0.802 0.197
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.802 0.197
E24.3 Ectopic ACTH syndrome
0.000 0.802 0.197
E24.1 Nelson's syndrome
0.000 0.802 0.197
E23.7 Disorder of pituitary gland, unspecified
0.000 0.804 0.196
E24.2 Drug-induced Cushing's syndrome
0.000 0.805 0.195
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.812 0.188
E23.1 Drug-induced hypopituitarism
0.000 0.812 0.188
E29.1 Testicular hypofunction
0.000 0.818 0.182
E13.9 Without complications
0.001 0.819 0.180
E21.4 Other specified disorders of parathyroid gland
0.000 0.823 0.177
E21.2 Other hyperparathyroidism
0.000 0.823 0.177
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.830 0.170
E21.0 Primary hyperparathyroidism
0.000 0.833 0.167
E05.5 Thyroid crisis or storm
0.000 0.833 0.166
E05.4 Thyrotoxicosis factitia
0.000 0.833 0.166
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.833 0.166
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.833 0.166
E61.1 Iron deficiency
0.001 0.834 0.165
E24.9 Cushing's syndrome, unspecified
0.000 0.835 0.165
E07.9 Disorder of thyroid, unspecified
0.000 0.844 0.155
E21.3 Hyperparathyroidism, unspecified
0.000 0.846 0.154
E46 Unspecified protein-energy malnutrition
0.001 0.847 0.151
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.851 0.149
E66 Obesity
0.000 0.851 0.149
E05.8 Other thyrotoxicosis
0.000 0.856 0.144
E24.0 Pituitary-dependent Cushing's disease
0.001 0.860 0.139
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.882 0.117
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.885 0.115
E66.1 Drug-induced obesity
0.000 0.893 0.107
E23.2 Diabetes insipidus
0.001 0.901 0.098
E66.0 Obesity due to excess calories
0.000 0.902 0.097
E05.9 Thyrotoxicosis, unspecified
0.000 0.909 0.091
E23.0 Hypopituitarism
0.000 0.909 0.090
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.917 0.083
E66.8 Other obesity
0.000 0.935 0.065
R20.2 Paraesthesia of skin
0.061 0.939 0.000
H36.0 Diabetic retinopathy
0.000 0.959 0.041
E70-E90 Metabolic disorders
0.000 0.968 0.032
E11.9 Without complications
0.000 0.971 0.029
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.975 0.024
E83 Disorders of mineral metabolism
0.000 0.977 0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.977 0.023
E77 Disorders of glycoprotein metabolism
0.000 0.977 0.023
E76 Disorders of glycosaminoglycan metabolism
0.000 0.977 0.023
E72 Other disorders of amino-acid metabolism
0.000 0.977 0.023
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.977 0.023
E70 Disorders of aromatic amino-acid metabolism
0.000 0.977 0.023
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.977 0.023
E79 Disorders of purine and pyrimidine metabolism
0.000 0.977 0.023
R20 Disturbances of skin sensation
0.022 0.978 0.000
E84 Cystic fibrosis
0.000 0.978 0.022
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.978 0.022
E74 Other disorders of carbohydrate metabolism
0.000 0.978 0.021
N81.2 Incomplete uterovaginal prolapse
0.021 0.979 0.000
E88 Other metabolic disorders
0.000 0.979 0.020
E83.4 Disorders of magnesium metabolism
0.000 0.980 0.020
E83.1 Disorders of iron metabolism
0.000 0.981 0.019
E89.2 Postprocedural hypoparathyroidism
0.000 0.981 0.019
E80.6 Other disorders of bilirubin metabolism
0.000 0.981 0.019
R20.3 Hyperaesthesia
0.019 0.981 0.000
E73 Lactose intolerance
0.000 0.981 0.018
E80.4 Gilbert's syndrome
0.000 0.982 0.018
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.982 0.018
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.982 0.018
E80.5 Crigler-Najjar syndrome
0.000 0.982 0.018
E80.3 Defects of catalase and peroxydase
0.000 0.982 0.018
E80.2 Other porphyria
0.000 0.982 0.018
E80.1 Porphyria cutanea tarda
0.000 0.982 0.018
E80.0 Hereditary erythropoietic porphyria
0.000 0.982 0.018
H36 Retinal disorders in diseases classified elsewhere
0.000 0.982 0.018
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.983 0.017
E83.8 Other disorders of mineral metabolism
0.000 0.983 0.017
E83.2 Disorders of zinc metabolism
0.000 0.983 0.017
E83.0 Disorders of copper metabolism
0.000 0.983 0.017
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.983 0.017
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.983 0.017
E89.5 Postprocedural testicular hypofunction
0.000 0.983 0.017
E89.1 Postprocedural hypoinsulinaemia
0.000 0.983 0.017
E89.3 Postprocedural hypopituitarism
0.000 0.983 0.017
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.983 0.017
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.983 0.017
E70.3 Albinism
0.000 0.983 0.017
E70.2 Disorders of tyrosine metabolism
0.000 0.983 0.017
E70.1 Other hyperphenylalaninaemias
0.000 0.983 0.017
E70.0 Classical phenylketonuria
0.000 0.983 0.017
E71.3 Disorders of fatty-acid metabolism
0.000 0.983 0.017
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.983 0.017
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.983 0.017
E71.0 Maple-syrup-urine disease
0.000 0.983 0.017
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.983 0.017
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.983 0.017
E72.5 Disorders of glycine metabolism
0.000 0.983 0.017
E72.4 Disorders of ornithine metabolism
0.000 0.983 0.017
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.983 0.017
E72.2 Disorders of urea cycle metabolism
0.000 0.983 0.017
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.983 0.017
E72.0 Disorders of amino-acid transport
0.000 0.983 0.017
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.983 0.017
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.983 0.017
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.983 0.017
E76.2 Other mucopolysaccharidoses
0.000 0.983 0.017
E76.1 Mucopolysaccharidosis, type II
0.000 0.983 0.017
E76.0 Mucopolysaccharidosis, type I
0.000 0.983 0.017
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.983 0.017
E77.8 Other disorders of glycoprotein metabolism
0.000 0.983 0.017
E77.1 Defects in glycoprotein degradation
0.000 0.983 0.017
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.983 0.017
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.983 0.016
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.983 0.016
E79.1 Lesch-Nyhan syndrome
0.000 0.983 0.016
E89.4 Postprocedural ovarian failure
0.000 0.984 0.016
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.984 0.016
E89.0 Postprocedural hypothyroidism
0.000 0.984 0.016
E84.8 Cystic fibrosis with other manifestations
0.000 0.984 0.016
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.984 0.016
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.984 0.016
E85 Amyloidosis
0.000 0.984 0.016
R20.1 Hypoaesthesia of skin
0.016 0.984 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.984 0.016
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.984 0.016
E75.3 Sphingolipidosis, unspecified
0.000 0.984 0.016
E75.2 Other sphingolipidosis
0.000 0.984 0.016
E75.1 Other gangliosidosis
0.000 0.984 0.016
E75.0 GM2 gangliosidosis
0.000 0.984 0.016
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.984 0.016
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.984 0.016
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.984 0.016
E74.2 Disorders of galactose metabolism
0.000 0.984 0.016
E74.1 Disorders of fructose metabolism
0.000 0.984 0.016
E74.0 Glycogen storage disease
0.000 0.984 0.016
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.984 0.015
R20.0 Anaesthesia of skin
0.015 0.985 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.985 0.015
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.985 0.015
E75.5 Other lipid storage disorders
0.000 0.985 0.014
E88.2 Lipomatosis, not elsewhere classified
0.000 0.986 0.014
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.986 0.014
E73.8 Other lactose intolerance
0.000 0.986 0.013
E73.1 Secondary lactase deficiency
0.000 0.986 0.013
E73.0 Congenital lactase deficiency
0.000 0.986 0.013
E88.8 Other specified metabolic disorders
0.000 0.987 0.013
Y85.0 Sequelae of motor-vehicle accident
0.000 0.987 0.013
E83.5 Disorders of calcium metabolism
0.000 0.987 0.013
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.987 0.013
M19.97 Arthrosis, unspecified (Ankle and foot)
0.013 0.987 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.988 0.012
E83.3 Disorders of phosphorus metabolism
0.000 0.988 0.012
E88.3 Tumour lysis syndrome
0.000 0.988 0.012
E85.8 Other amyloidosis
0.000 0.988 0.011
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.988 0.011
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.988 0.011
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.988 0.011
E85.3 Secondary systemic amyloidosis
0.000 0.988 0.011
R20.8 Other and unspecified disturbances of skin sensation
0.012 0.988 0.000
I35.0 Aortic (valve) stenosis
0.011 0.989 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.989 0.011
E85.4 Organ-limited amyloidosis
0.000 0.990 0.010
E73.9 Lactose intolerance, unspecified
0.000 0.991 0.009
E78.2 Mixed hyperlipidaemia
0.000 0.991 0.009
E86 Volume depletion
0.000 0.991 0.009
E78.1 Pure hyperglyceridaemia
0.000 0.991 0.009
E78.4 Other hyperlipidaemia
0.000 0.991 0.008
T84.0 Mechanical complication of internal joint prosthesis
0.008 0.992 0.000
E78.6 Lipoprotein deficiency
0.000 0.992 0.008
E85.9 Amyloidosis, unspecified
0.001 0.992 0.007
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.992 0.008
E78.3 Hyperchylomicronaemia
0.000 0.992 0.008
L40.9 Psoriasis, unspecified
0.000 0.993 0.007
K91.4 Colostomy and enterostomy malfunction
0.000 0.993 0.007
Z87.8 Personal history of other specified conditions
0.000 0.994 0.006
I35 Nonrheumatic aortic valve disorders
0.006 0.994 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.994 0.006
L40 Psoriasis
0.000 0.994 0.006
K90.0 Coeliac disease
0.000 0.994 0.006
Y85 Sequelae of transport accidents
0.000 0.994 0.006
I35.2 Aortic (valve) stenosis with insufficiency
0.006 0.994 0.000
I35.1 Aortic (valve) insufficiency
0.006 0.994 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.006 0.994 0.000
L40.8 Other psoriasis
0.000 0.995 0.005
L40.5 Arthropathic psoriasis
0.000 0.995 0.005
I34.0 Mitral (valve) insufficiency
0.000 0.995 0.005
L40.0 Psoriasis vulgaris
0.000 0.995 0.005
I35.8 Other aortic valve disorders
0.005 0.995 0.000
L40.4 Guttate psoriasis
0.000 0.995 0.004
L40.2 Acrodermatitis continua
0.000 0.995 0.004
E66.9 Obesity, unspecified
0.000 0.995 0.004
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.995 0.005
L40.1 Generalised pustular psoriasis
0.000 0.996 0.004
M35.0 Sicca syndrome [Sjogren]
0.000 0.996 0.004
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.996 0.004
Y85.9 Sequelae of other and unspecified transport accidents
0.000 0.996 0.004
L40.3 Pustulosis palmaris et plantaris
0.000 0.996 0.004
E87.3 Alkalosis
0.000 0.996 0.004
M35.1 Other overlap syndromes
0.000 0.996 0.004
E87.4 Mixed disorder of acid-base balance
0.000 0.996 0.003
M35 Other systemic involvement of connective tissue
0.000 0.997 0.003
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.997 0.003
M35.7 Hypermobility syndrome
0.000 0.997 0.003
S52.60 Fracture of lower end of both ulna and radius (closed)
0.000 0.997 0.003
K14.8 Other diseases of tongue
0.000 0.997 0.003
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.997 0.003
I35.9 Aortic valve disorder, unspecified
0.003 0.997 0.000
K37 Unspecified appendicitis
0.000 0.997 0.003
A63.0 Anogenital (venereal) warts
0.000 0.997 0.003
K90 Intestinal malabsorption
0.000 0.997 0.003
Q50.4 Embryonic cyst of Fallopian tube
0.000 0.997 0.003
M35.2 Behcet's disease
0.000 0.997 0.003
E87.2 Acidosis
0.000 0.997 0.003
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.997 0.003
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.997 0.003
M35.5 Multifocal fibrosclerosis
0.000 0.997 0.003
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.997 0.003
U80.1 Methicillin resistant agent
0.000 0.997 0.003
S60.9 Superficial injury of wrist and hand, unspecified
0.000 0.997 0.003
Q44.6 Cystic disease of liver
0.003 0.997 0.000
K12.1 Other forms of stomatitis
0.000 0.997 0.003
M35.3 Polymyalgia rheumatica
0.000 0.997 0.003
Q76 Congenital malformations of spine and bony thorax
0.003 0.997 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.997 0.003
L40-L45 Papulosquamous disorders
0.000 0.997 0.003
Q76.0 Spina bifida occulta
0.002 0.997 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.997 0.002
Q66.9 Congenital deformity of feet, unspecified
0.002 0.997 0.000
Q51.2 Other doubling of uterus
0.002 0.997 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.002 0.997 0.000
K90.8 Other intestinal malabsorption
0.000 0.998 0.002
Q66 Congenital deformities of feet
0.002 0.998 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.998 0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.002 0.998 0.000
N39.9 Disorder of urinary system, unspecified
0.000 0.998 0.002
D06.9 Cervix, unspecified
0.000 0.998 0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.002 0.998 0.000
H52.3 Anisometropia and aniseikonia
0.002 0.998 0.000
L42 Pityriasis rosea
0.000 0.998 0.002
K90.3 Pancreatic steatorrhoea
0.000 0.998 0.002
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.998 0.002
K90.1 Tropical sprue
0.000 0.998 0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.002 0.998 0.000
K14.0 Glossitis
0.000 0.998 0.002
L29.9 Pruritus, unspecified
0.000 0.998 0.002
M31.6 Other giant cell arteritis
0.002 0.998 0.000
Q65 Congenital deformities of hip
0.002 0.998 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.998 0.002
M31.3 Wegener's granulomatosis
0.002 0.998 0.000
D12.8 Rectum
0.000 0.998 0.002
G60.0 Hereditary motor and sensory neuropathy
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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