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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1362075
log Bayes Factor = 41.8309
Chromosome 6   position 29,482,128  (GRCh37) Explore rs1362075 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.003 0.997
E10.2 With renal complications
0.000 0.030 0.970
E10.4 With neurological complications
0.000 0.030 0.970
E14 Unspecified diabetes mellitus
0.000 0.038 0.962
E13 Other specified diabetes mellitus
0.000 0.060 0.940
E11 Non-insulin-dependent diabetes mellitus
0.000 0.062 0.938
E11.2 With renal complications
0.000 0.081 0.919
E10.5 With peripheral circulatory complications
0.000 0.095 0.905
E13.9 Without complications
0.000 0.111 0.889
E10.6 With other specified complications
0.000 0.132 0.868
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.151 0.849
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.156 0.844
E16 Other disorders of pancreatic internal secretion
0.000 0.158 0.842
E14.5 With peripheral circulatory complications
0.000 0.163 0.837
E16.2 Hypoglycaemia, unspecified
0.000 0.165 0.835
E10.0 With coma
0.000 0.210 0.790
E14.3 With ophthalmic complications
0.000 0.221 0.779
E14.4 With neurological complications
0.000 0.229 0.771
E11.5 With peripheral circulatory complications
0.000 0.233 0.767
E11.1 With ketoacidosis
0.000 0.237 0.763
E14.6 With other specified complications
0.000 0.251 0.749
E10.8 With unspecified complications
0.000 0.256 0.744
E50-E64 Other nutritional deficiencies
0.000 0.257 0.743
E14.9 Without complications
0.000 0.260 0.740
E14.1 With ketoacidosis
0.000 0.265 0.735
E16.1 Other hypoglycaemia
0.000 0.269 0.731
E14.8 With unspecified complications
0.000 0.273 0.727
E13.3 With ophthalmic complications
0.000 0.274 0.725
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E11.0 With coma
0.000 0.303 0.697
E14.2 Withrenal complications
0.000 0.309 0.691
E14.7 With multiple complications
0.000 0.310 0.689
E14.0 With coma
0.000 0.310 0.689
K50 Crohn's disease [regional enteritis]
0.685 0.315 0.000
K51 Ulcerative colitis
0.682 0.318 0.000
K50.9 Crohn's disease, unspecified
0.679 0.321 0.000
E13.8 With unspecified complications
0.000 0.326 0.674
E13.7 With multiple complications
0.000 0.326 0.674
E13.6 With other specified complications
0.000 0.326 0.674
E13.5 With peripheral circulatory complications
0.000 0.326 0.674
E13.4 With neurological complications
0.000 0.326 0.674
E13.2 With renal complications
0.000 0.326 0.674
E13.1 With ketoacidosis
0.000 0.326 0.674
E13.0 With coma
0.000 0.326 0.674
E11.7 With multiple complications
0.000 0.327 0.673
K50-K52 Noninfective enteritis and colitis
0.670 0.330 0.000
E11.8 With unspecified complications
0.000 0.333 0.667
K50.0 Crohn's disease of small intestine
0.665 0.335 0.000
K51.9 Ulcerative colitis, unspecified
0.661 0.339 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.355 0.645
K51.4 Pseudopolyposis of colon
0.630 0.370 0.000
K51.2 Ulcerative (chronic) proctitis
0.625 0.375 0.000
E61 Deficiency of other nutrient elements
0.000 0.381 0.619
E20-E35 Disorders of other endocrine glands
0.000 0.386 0.614
E15 Nondiabetic hypoglycaemic coma
0.000 0.394 0.605
E11.6 With other specified complications
0.000 0.395 0.605
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.396 0.604
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.396 0.604
E16.4 Abnormal secretion of gastrin
0.000 0.396 0.604
E16.3 Increased secretion of glucagon
0.000 0.396 0.604
E55 Vitamin D deficiency
0.000 0.402 0.598
E00-E07 Disorders of thyroid gland
0.000 0.404 0.596
E51 Thiamine deficiency
0.000 0.421 0.579
E11.4 With neurological complications
0.000 0.421 0.579
E24 Cushing's syndrome
0.000 0.422 0.578
K51.3 Ulcerative (chronic) rectosigmoiditis
0.569 0.431 0.000
E56 Other vitamin deficiencies
0.000 0.440 0.560
K50.8 Other Crohn's disease
0.558 0.442 0.000
E61.1 Iron deficiency
0.000 0.453 0.547
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.458 0.542
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.467 0.533
E63 Other nutritional deficiencies
0.000 0.467 0.533
E50 Vitamin A deficiency
0.000 0.467 0.533
E60 Dietary zinc deficiency
0.000 0.467 0.533
E59 Dietary selenium deficiency
0.000 0.467 0.533
E54 Ascorbic acid deficiency
0.000 0.467 0.533
E52 Niacin deficiency [pellagra]
0.000 0.467 0.533
E53 Deficiency of other B group vitamins
0.000 0.469 0.531
K51.8 Other ulcerative colitis
0.530 0.470 0.000
E07 Other disorders of thyroid
0.000 0.472 0.528
K51.5 Mucosal proctocolitis
0.527 0.473 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E24.9 Cushing's syndrome, unspecified
0.000 0.488 0.512
E24.0 Pituitary-dependent Cushing's disease
0.000 0.494 0.506
K51.0 Ulcerative (chronic) enterocolitis
0.502 0.498 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.501 0.499
E40-E46 Malnutrition
0.000 0.505 0.495
E55.9 Vitamin D deficiency, unspecified
0.000 0.505 0.495
E11.3 With ophthalmic complications
0.000 0.524 0.476
E58 Dietary calcium deficiency
0.000 0.530 0.470
K51.1 Ulcerative (chronic) ileocolitis
0.465 0.535 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.535 0.465
E51.2 Wernicke's encephalopathy
0.000 0.538 0.462
E23.0 Hypopituitarism
0.000 0.539 0.461
E07.8 Other specified disorders of thyroid
0.000 0.543 0.457
E20 Hypoparathyroidism
0.000 0.544 0.456
K50.1 Crohn's disease of large intestine
0.454 0.546 0.000
E28 Ovarian dysfunction
0.000 0.549 0.451
E61.9 Deficiency of nutrient element, unspecified
0.000 0.556 0.444
E61.8 Deficiency of other specified nutrient elements
0.000 0.556 0.444
E61.7 Deficiency of multiple nutrient elements
0.000 0.556 0.444
E61.6 Vanadium deficiency
0.000 0.556 0.444
E61.5 Molybdenum deficiency
0.000 0.556 0.444
E61.4 Chromium deficiency
0.000 0.556 0.444
E61.3 Manganese deficiency
0.000 0.556 0.444
E61.0 Copper deficiency
0.000 0.556 0.444
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.560 0.440
E32 Diseases of thymus
0.000 0.560 0.440
E30 Disorders of puberty, not elsewhere classified
0.000 0.560 0.440
E25 Adrenogenital disorders
0.000 0.560 0.440
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.566 0.434
E24.2 Drug-induced Cushing's syndrome
0.000 0.567 0.433
E55.0 Rickets, active
0.000 0.571 0.429
E56.1 Deficiency of vitamin K
0.000 0.572 0.428
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.573 0.427
E00 Congenital iodine-deficiency syndrome
0.000 0.573 0.427
E07.9 Disorder of thyroid, unspecified
0.000 0.573 0.427
E11.9 Without complications
0.000 0.575 0.425
E53.9 Vitamin B deficiency, unspecified
0.000 0.577 0.423
E51.9 Thiamine deficiency, unspecified
0.000 0.584 0.415
E51.8 Other manifestations of thiamine deficiency
0.000 0.584 0.415
E51.1 Beriberi
0.000 0.584 0.415
K90 Intestinal malabsorption
0.001 0.585 0.414
E24.8 Other Cushing's syndrome
0.000 0.586 0.414
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.586 0.414
E24.3 Ectopic ACTH syndrome
0.000 0.586 0.414
E24.1 Nelson's syndrome
0.000 0.586 0.414
E31 Polyglandular dysfunction
0.000 0.590 0.410
E61.2 Magnesium deficiency
0.000 0.594 0.406
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.597 0.403
E56.9 Vitamin deficiency, unspecified
0.000 0.599 0.401
E56.8 Deficiency of other vitamins
0.000 0.599 0.401
E56.0 Deficiency of vitamin E
0.000 0.599 0.401
E06 Thyroiditis
0.000 0.601 0.399
N84.1 Polyp of cervix uteri
0.393 0.607 0.000
E23.2 Diabetes insipidus
0.000 0.608 0.392
E05.5 Thyroid crisis or storm
0.000 0.611 0.389
E05.4 Thyrotoxicosis factitia
0.000 0.611 0.389
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.611 0.389
E23.7 Disorder of pituitary gland, unspecified
0.000 0.612 0.388
E22 Hyperfunction of pituitary gland
0.000 0.616 0.384
E05.8 Other thyrotoxicosis
0.000 0.617 0.383
E50.9 Vitamin A deficiency, unspecified
0.000 0.618 0.382
E50.8 Other manifestations of vitamin A deficiency
0.000 0.618 0.382
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.618 0.382
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.618 0.382
E50.5 Vitamin A deficiency with night blindness
0.000 0.618 0.382
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.618 0.382
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.618 0.382
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.618 0.382
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.618 0.382
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.618 0.382
E63.9 Nutritional deficiency, unspecified
0.000 0.618 0.382
E63.8 Other specified nutritional deficiencies
0.000 0.618 0.382
E63.1 Imbalance of constituents of food intake
0.000 0.618 0.382
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.618 0.382
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.618 0.382
E64.8 Sequelae of other nutritional deficiencies
0.000 0.618 0.382
E64.3 Sequelae of rickets
0.000 0.618 0.382
E64.2 Sequelae of vitamin C deficiency
0.000 0.618 0.382
E64.1 Sequelae of vitamin A deficiency
0.000 0.618 0.382
E64.0 Sequelae of protein-energy malnutrition
0.000 0.618 0.382
E53.1 Pyridoxine deficiency
0.000 0.619 0.380
E53.0 Riboflavin deficiency
0.000 0.619 0.380
E07.1 Dyshormogenetic goitre
0.000 0.621 0.379
E07.0 Hypersecretion of calcitonin
0.000 0.621 0.379
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.623 0.377
E29 Testicular dysfunction
0.000 0.627 0.373
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.628 0.372
E23.1 Drug-induced hypopituitarism
0.000 0.628 0.372
E28.3 Primary ovarian failure
0.000 0.634 0.366
E34 Other endocrine disorders
0.000 0.635 0.364
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.645 0.355
E45 Retarded development following protein-energy malnutrition
0.000 0.645 0.355
E43 Unspecified severe protein-energy malnutrition
0.000 0.645 0.355
E42 Marasmic kwashiorkor
0.000 0.645 0.355
E41 Nutritional marasmus
0.000 0.645 0.355
E40 Kwashiorkor
0.000 0.645 0.355
E21.3 Hyperparathyroidism, unspecified
0.000 0.651 0.349
E20.9 Hypoparathyroidism, unspecified
0.000 0.656 0.344
K90.9 Intestinal malabsorption, unspecified
0.000 0.659 0.341
E06.9 Thyroiditis, unspecified
0.000 0.661 0.339
E26 Hyperaldosteronism
0.000 0.670 0.330
E20.8 Other hypoparathyroidism
0.000 0.673 0.327
E20.1 Pseudohypoparathyroidism
0.000 0.673 0.327
E20.0 Idiopathic hypoparathyroidism
0.000 0.673 0.327
E28.9 Ovarian dysfunction, unspecified
0.000 0.676 0.323
E28.8 Other ovarian dysfunction
0.000 0.676 0.323
E28.1 Androgen excess
0.000 0.676 0.323
E28.0 Oestrogen excess
0.000 0.676 0.323
E65-E68 Obesity and other hyperalimentation
0.000 0.681 0.319
E53.8 Deficiency of other specified B group vitamins
0.000 0.682 0.318
E25.9 Adrenogenital disorder, unspecified
0.000 0.684 0.315
E25.8 Other adrenogenital disorders
0.000 0.684 0.315
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.684 0.315
E30.9 Disorder of puberty, unspecified
0.000 0.684 0.315
E30.8 Other disorders of puberty
0.000 0.684 0.315
E30.1 Precocious puberty
0.000 0.684 0.315
E30.0 Delayed puberty
0.000 0.684 0.315
E32.9 Disease of thymus, unspecified
0.000 0.684 0.315
E32.8 Other diseases of thymus
0.000 0.684 0.315
E32.1 Abscess of thymus
0.000 0.684 0.315
E32.0 Persistent hyperplasia of thymus
0.000 0.684 0.315
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.684 0.315
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.684 0.315
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.684 0.315
E21.4 Other specified disorders of parathyroid gland
0.000 0.689 0.311
E22.0 Acromegaly and pituitary gigantism
0.000 0.693 0.307
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.693 0.306
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.693 0.306
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.693 0.306
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.693 0.306
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.693 0.306
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.693 0.306
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.693 0.306
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.693 0.306
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.694 0.306
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.697 0.303
E34.8 Other specified endocrine disorders
0.000 0.698 0.302
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.699 0.300
K90.8 Other intestinal malabsorption
0.001 0.701 0.298
E21.2 Other hyperparathyroidism
0.000 0.702 0.298
K90.3 Pancreatic steatorrhoea
0.001 0.702 0.297
K90.2 Blind loop syndrome, not elsewhere classified
0.001 0.702 0.297
K90.1 Tropical sprue
0.001 0.702 0.297
E31.9 Polyglandular dysfunction, unspecified
0.000 0.706 0.294
E31.8 Other polyglandular dysfunction
0.000 0.706 0.294
E31.1 Polyglandular hyperfunction
0.000 0.706 0.294
E23.6 Other disorders of pituitary gland
0.000 0.707 0.292
E06.1 Subacute thyroiditis
0.000 0.708 0.292
E21.0 Primary hyperparathyroidism
0.000 0.711 0.289
E06.4 Drug-induced thyroiditis
0.000 0.714 0.286
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.714 0.286
E06.0 Acute thyroiditis
0.000 0.714 0.286
E27 Other disorders of adrenal gland
0.000 0.721 0.279
E28.2 Polycystic ovarian syndrome
0.000 0.723 0.277
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.724 0.275
E22.8 Other hyperfunction of pituitary gland
0.000 0.724 0.275
E29.9 Testicular dysfunction, unspecified
0.000 0.732 0.268
E29.8 Other testicular dysfunction
0.000 0.732 0.268
E29.0 Testicular hyperfunction
0.000 0.732 0.268
E31.0 Autoimmune polyglandular failure
0.000 0.735 0.264
E34.5 Androgen resistance syndrome
0.000 0.738 0.261
E34.4 Constitutional tall stature
0.000 0.738 0.261
E34.3 Short stature, not elsewhere classified
0.000 0.738 0.261
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.738 0.261
E34.1 Other hypersecretion of intestinal hormones
0.000 0.738 0.261
E44.1 Mild protein-energy malnutrition
0.000 0.745 0.254
E44.0 Moderate protein-energy malnutrition
0.000 0.745 0.254
E27.1 Primary adrenocortical insufficiency
0.000 0.747 0.253
E46 Unspecified protein-energy malnutrition
0.000 0.759 0.241
E26.8 Other hyperaldosteronism
0.000 0.763 0.236
E26.1 Secondary hyperaldosteronism
0.000 0.763 0.236
E22.1 Hyperprolactinaemia
0.000 0.764 0.236
E26.9 Hyperaldosteronism, unspecified
0.000 0.764 0.235
E67 Other hyperalimentation
0.000 0.771 0.229
E68 Sequelae of hyperalimentation
0.000 0.771 0.229
E06.3 Autoimmune thyroiditis
0.000 0.777 0.223
E06.5 Other chronic thyroiditis
0.000 0.778 0.221
E03 Other hypothyroidism
0.000 0.782 0.218
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.786 0.214
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.001 0.789 0.210
E34.9 Endocrine disorder, unspecified
0.000 0.798 0.202
E29.1 Testicular hypofunction
0.000 0.799 0.201
E27.5 Adrenomedullary hyperfunction
0.000 0.800 0.200
E27.0 Other adrenocortical overactivity
0.000 0.800 0.200
E27.8 Other specified disorders of adrenal gland
0.000 0.805 0.195
E65 Localised adiposity
0.000 0.807 0.193
E34.0 Carcinoid syndrome
0.000 0.821 0.179
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.831 0.169
E03.8 Other specified hypothyroidism
0.000 0.832 0.167
E03.1 Congenital hypothyroidism without goitre
0.000 0.833 0.167
E67.8 Other specified hyperalimentation
0.000 0.836 0.164
E67.3 Hypervitaminosis D
0.000 0.836 0.164
E67.2 Megavitamin-B6 syndrome
0.000 0.836 0.164
E67.1 Hypercarotenaemia
0.000 0.836 0.164
E67.0 Hypervitaminosis A
0.000 0.836 0.164
E03.5 Myxoedema coma
0.000 0.843 0.156
E03.4 Atrophy of thyroid (acquired)
0.000 0.843 0.156
E03.3 Postinfectious hypothyroidism
0.000 0.843 0.156
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.843 0.156
E27.9 Disorder of adrenal gland, unspecified
0.000 0.854 0.146
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.868 0.132
E26.0 Primary hyperaldosteronism
0.001 0.871 0.128
E04 Other non-toxic goitre
0.000 0.877 0.123
E27.2 Addisonian crisis
0.001 0.878 0.121
E83 Disorders of mineral metabolism
0.106 0.889 0.005
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.894 0.105
E04.9 Non-toxic goitre, unspecified
0.000 0.900 0.100
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.901 0.099
Z99.1 Dependence on respirator
0.000 0.910 0.090
E04.8 Other specified non-toxic goitre
0.000 0.911 0.088
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.916 0.084
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.918 0.082
E83.8 Other disorders of mineral metabolism
0.076 0.920 0.003
E83.2 Disorders of zinc metabolism
0.076 0.920 0.003
E83.0 Disorders of copper metabolism
0.076 0.920 0.003
E83.9 Disorder of mineral metabolism, unspecified
0.071 0.925 0.004
E83.3 Disorders of phosphorus metabolism
0.072 0.926 0.002
K52 Other non-infective gastro-enteritis and colitis
0.070 0.929 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.939 0.060
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.939 0.060
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.939 0.060
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.939 0.060
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.942 0.058
K52.0 Gastro-enteritis and colitis due to radiation
0.057 0.943 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.947 0.052
E83.4 Disorders of magnesium metabolism
0.049 0.949 0.002
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.951 0.049
Z99.8 Dependence on other enabling machines and devices
0.000 0.951 0.049
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.046 0.954 0.000
E66 Obesity
0.000 0.954 0.046
K52.3 Indeterminate colitis
0.044 0.956 0.000
E70-E90 Metabolic disorders
0.000 0.960 0.039
E73 Lactose intolerance
0.000 0.961 0.038
E73.9 Lactose intolerance, unspecified
0.000 0.962 0.038
K52.1 Toxic gastro-enteritis and colitis
0.038 0.962 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.964 0.036
Z99.4 Dependence on artificial heart
0.000 0.964 0.036
Z99.0 Dependence on aspirator
0.000 0.964 0.036
E04.2 Non-toxic multinodular goitre
0.000 0.965 0.035
E66.1 Drug-induced obesity
0.000 0.967 0.033
J38.3 Other diseases of vocal cords
0.032 0.968 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.969 0.031
E66.0 Obesity due to excess calories
0.000 0.969 0.031
N84 Polyp of female genital tract
0.031 0.969 0.000
J38.7 Other diseases of larynx
0.031 0.969 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.030 0.970 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.970 0.030
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.970 0.030
E84 Cystic fibrosis
0.000 0.970 0.030
J38.4 Oedema of larynx
0.029 0.971 0.000
E83.5 Disorders of calcium metabolism
0.028 0.971 0.001
E77 Disorders of glycoprotein metabolism
0.000 0.971 0.028
E76 Disorders of glycosaminoglycan metabolism
0.000 0.971 0.028
E72 Other disorders of amino-acid metabolism
0.000 0.971 0.028
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.971 0.028
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.971 0.028
E70 Disorders of aromatic amino-acid metabolism
0.000 0.972 0.028
E73.8 Other lactose intolerance
0.000 0.972 0.028
E73.1 Secondary lactase deficiency
0.000 0.972 0.028
E73.0 Congenital lactase deficiency
0.000 0.972 0.028
K90-K93 Other diseases of the digestive system
0.004 0.972 0.024
F45.8 Other somatoform disorders
0.000 0.973 0.027
E04.1 Non-toxic single thyroid nodule
0.000 0.974 0.026
E88 Other metabolic disorders
0.000 0.974 0.026
J38.5 Laryngeal spasm
0.026 0.974 0.000
E85 Amyloidosis
0.000 0.974 0.025
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.026 0.974 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.975 0.025
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.975 0.025
N84.9 Polyp of female genital tract, unspecified
0.024 0.976 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.976 0.024
E75.5 Other lipid storage disorders
0.000 0.976 0.024
K59.8 Other specified functional intestinal disorders
0.024 0.976 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.977 0.023
E74.0 Glycogen storage disease
0.000 0.977 0.023
J38.2 Nodules of vocal cords
0.023 0.977 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.977 0.022
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.977 0.022
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.977 0.022
E74.2 Disorders of galactose metabolism
0.000 0.977 0.022
E74.1 Disorders of fructose metabolism
0.000 0.977 0.022
Z99.3 Dependence on wheelchair
0.000 0.978 0.022
E75.6 Lipid storage disorder, unspecified
0.000 0.978 0.022
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.978 0.022
E75.3 Sphingolipidosis, unspecified
0.000 0.978 0.022
E75.2 Other sphingolipidosis
0.000 0.978 0.022
E75.1 Other gangliosidosis
0.000 0.978 0.022
E75.0 GM2 gangliosidosis
0.000 0.978 0.022
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.978 0.022
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.978 0.022
E79.1 Lesch-Nyhan syndrome
0.000 0.978 0.022
E84.8 Cystic fibrosis with other manifestations
0.000 0.978 0.022
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.978 0.022
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.978 0.022
E85.4 Organ-limited amyloidosis
0.000 0.979 0.021
N84.8 Polyp of other parts of female genital tract
0.021 0.979 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.979 0.021
E71.3 Disorders of fatty-acid metabolism
0.000 0.979 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.979 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.979 0.020
E71.0 Maple-syrup-urine disease
0.000 0.979 0.020
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.979 0.020
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.979 0.020
E72.5 Disorders of glycine metabolism
0.000 0.979 0.020
E72.4 Disorders of ornithine metabolism
0.000 0.979 0.020
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.979 0.020
E72.2 Disorders of urea cycle metabolism
0.000 0.979 0.020
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.979 0.020
E72.0 Disorders of amino-acid transport
0.000 0.979 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.979 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.979 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.979 0.020
E76.2 Other mucopolysaccharidoses
0.000 0.979 0.020
E76.1 Mucopolysaccharidosis, type II
0.000 0.979 0.020
E76.0 Mucopolysaccharidosis, type I
0.000 0.979 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.979 0.020
E77.8 Other disorders of glycoprotein metabolism
0.000 0.979 0.020
E77.1 Defects in glycoprotein degradation
0.000 0.979 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.979 0.020
K40 Inguinal hernia
0.021 0.979 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.980 0.020
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.980 0.020
E70.2 Disorders of tyrosine metabolism
0.000 0.980 0.020
E70.1 Other hyperphenylalaninaemias
0.000 0.980 0.020
E70.0 Classical phenylketonuria
0.000 0.980 0.020
J38.6 Stenosis of larynx
0.020 0.980 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.003 0.980 0.017
E70.3 Albinism
0.000 0.980 0.019
F45 Somatoform disorders
0.000 0.980 0.020
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.981 0.019
E88.9 Metabolic disorder, unspecified
0.000 0.981 0.019
L40.9 Psoriasis, unspecified
0.000 0.981 0.019
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.981 0.018
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.981 0.018
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.981 0.018
K43 Ventral hernia
0.019 0.981 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.018 0.982 0.000
J38.0 Paralysis of vocal cords and larynx
0.018 0.982 0.000
J38.1 Polyp of vocal cord and larynx
0.018 0.982 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.982 0.018
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.018 0.982 0.000
E85.8 Other amyloidosis
0.000 0.982 0.017
K41 Femoral hernia
0.017 0.983 0.000
K40-K46 Hernia
0.017 0.983 0.000
E88.3 Tumour lysis syndrome
0.000 0.983 0.017
K43.0 Ventral hernia with obstruction, without gangrene
0.017 0.983 0.000
E66.8 Other obesity
0.000 0.983 0.017
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.983 0.017
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.017 0.983 0.000
E88.8 Other specified metabolic disorders
0.000 0.983 0.017
E85.3 Secondary systemic amyloidosis
0.000 0.983 0.016
F45.9 Somatoform disorder, unspecified
0.000 0.984 0.016
Z99.2 Dependence on renal dialysis
0.000 0.984 0.016
N00-N08 Glomerular diseases
0.000 0.984 0.016
F45.2 Hypochondriacal disorder
0.000 0.984 0.016
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.016 0.984 0.000
N84.3 Polyp of vulva
0.016 0.984 0.000
N84.2 Polyp of vagina
0.016 0.984 0.000
F45.0 Somatisation disorder
0.000 0.984 0.016
E80.6 Other disorders of bilirubin metabolism
0.000 0.984 0.015
M31.6 Other giant cell arteritis
0.000 0.984 0.016
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.984 0.015
E80.5 Crigler-Najjar syndrome
0.000 0.984 0.015
E80.3 Defects of catalase and peroxydase
0.000 0.984 0.015
E80.0 Hereditary erythropoietic porphyria
0.000 0.984 0.015
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.015 0.985 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.015 0.985 0.000
E85.9 Amyloidosis, unspecified
0.000 0.985 0.015
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.002 0.985 0.013
K93.1 Megacolon in Chagas' disease
0.002 0.985 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.002 0.985 0.013
F45.1 Undifferentiated somatoform disorder
0.000 0.986 0.014
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.014 0.986 0.000
E80.2 Other porphyria
0.000 0.986 0.014
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.014 0.986 0.000
F45.4 Persistent somatoform pain disorder
0.000 0.986 0.014
K43.7 Other and unspecified ventral hernia with gangrene
0.014 0.986 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.014 0.986 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.014 0.986 0.000
K43.4 Parastomal hernia with gangrene
0.014 0.986 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.014 0.986 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.014 0.986 0.000
K43.1 Ventral hernia with gangrene
0.014 0.986 0.000
F45.3 Somatoform autonomic dysfunction
0.000 0.987 0.013
E80.1 Porphyria cutanea tarda
0.000 0.987 0.013
E80.4 Gilbert's syndrome
0.000 0.987 0.013
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.013 0.987 0.000
K41.1 Bilateral femoral hernia, with gangrene
0.013 0.987 0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.013 0.987 0.000
N04 Nephrotic syndrome
0.000 0.987 0.012
K46 Unspecified abdominal hernia
0.012 0.988 0.000
N05 Unspecified nephritic syndrome
0.000 0.988 0.012
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.988 0.012
N06 Isolated proteinuria with specified morphological lesion
0.000 0.988 0.012
N01 Rapidly progressive nephritic syndrome
0.000 0.988 0.012
N00 Acute nephritic syndrome
0.000 0.988 0.011
F41.1 Generalised anxiety disorder
0.000 0.989 0.011
L40 Psoriasis
0.000 0.989 0.011
L40.5 Arthropathic psoriasis
0.000 0.989 0.011
N05.1 Focal and segmental glomerular lesions
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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