TreeWAS – Variant ID: rs1362123

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.001	0.999
E10.9 Without complications	0.000	0.003	0.997
L40.0 Psoriasis vulgaris	0.997	0.003	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.004	0.996
E10-E14 Diabetes mellitus	0.000	0.017	0.983
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.017	0.983
E10.4 With neurological complications	0.000	0.040	0.960
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.059	0.941
M07.39 Other psoriatic arthropathies (Site unspecified)	0.940	0.060	0.000
M07.3 Other psoriatic arthropathies	0.939	0.061	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.935	0.065	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.090	0.910
E10.3 With ophthalmic complications	0.000	0.096	0.904
E10.5 With peripheral circulatory complications	0.000	0.104	0.896
L40.8 Other psoriasis	0.891	0.109	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.111	0.889
E07 Other disorders of thyroid	0.000	0.115	0.885
E10.1 With ketoacidosis	0.000	0.133	0.867
L40.1 Generalised pustular psoriasis	0.854	0.146	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.163	0.837
E10.6 With other specified complications	0.000	0.167	0.833
M07.34 Other psoriatic arthropathies (Hand)	0.825	0.175	0.000
E10.2 With renal complications	0.000	0.187	0.813
E10.0 With coma	0.000	0.189	0.811
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.199	0.801
M07.36 Other psoriatic arthropathies (Lower leg)	0.801	0.199	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.781	0.219	0.000
E06 Thyroiditis	0.000	0.231	0.769
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.246	0.754
E50-E64 Other nutritional deficiencies	0.000	0.272	0.728
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.276	0.724
E05.8 Other thyrotoxicosis	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.284	0.716
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.287	0.713
E12 Malnutrition-related diabetes mellitus	0.000	0.295	0.705
E15 Nondiabetic hypoglycaemic coma	0.000	0.326	0.674
M07.38 Other psoriatic arthropathies (Other)	0.674	0.326	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.674	0.326	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.674	0.326	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.674	0.326	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.674	0.326	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.347	0.653
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.347	0.653
E16.4 Abnormal secretion of gastrin	0.000	0.347	0.653
E16.3 Increased secretion of glucagon	0.000	0.347	0.653
E07.1 Dyshormogenetic goitre	0.000	0.366	0.634
E07.0 Hypersecretion of calcitonin	0.000	0.366	0.634
E03.8 Other specified hypothyroidism	0.000	0.397	0.603
E06.3 Autoimmune thyroiditis	0.000	0.401	0.599
E55 Vitamin D deficiency	0.000	0.436	0.564
E16.1 Other hypoglycaemia	0.000	0.440	0.560
E13 Other specified diabetes mellitus	0.000	0.440	0.559
E06.9 Thyroiditis, unspecified	0.000	0.442	0.558
E10.8 With unspecified complications	0.000	0.448	0.552
E06.5 Other chronic thyroiditis	0.000	0.448	0.552
E06.4 Drug-induced thyroiditis	0.000	0.448	0.552
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.448	0.552
E06.1 Subacute thyroiditis	0.000	0.448	0.552
E06.0 Acute thyroiditis	0.000	0.448	0.552
K90 Intestinal malabsorption	0.000	0.476	0.524
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.478	0.522
E63 Other nutritional deficiencies	0.000	0.478	0.522
E56 Other vitamin deficiencies	0.000	0.478	0.522
E51 Thiamine deficiency	0.000	0.478	0.522
E50 Vitamin A deficiency	0.000	0.478	0.522
E60 Dietary zinc deficiency	0.000	0.478	0.522
E59 Dietary selenium deficiency	0.000	0.478	0.522
E58 Dietary calcium deficiency	0.000	0.478	0.522
E54 Ascorbic acid deficiency	0.000	0.478	0.522
E52 Niacin deficiency [pellagra]	0.000	0.478	0.522
E53 Deficiency of other B group vitamins	0.000	0.485	0.514
E65-E68 Obesity and other hyperalimentation	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E61 Deficiency of other nutrient elements	0.000	0.492	0.508
E12.9 Without complications	0.000	0.494	0.505
E12.8 With unspecified complications	0.000	0.494	0.505
E12.7 With multiple complications	0.000	0.494	0.505
E12.6 With other specified complications	0.000	0.494	0.505
E12.5 With peripheral circulatory complications	0.000	0.494	0.505
E12.4 With neurological complications	0.000	0.494	0.505
E12.3 With ophthalmic complications	0.000	0.494	0.505
E12.2 With renal complications	0.000	0.494	0.505
E12.1 With ketoacidosis	0.000	0.494	0.505
E12.0 With coma	0.000	0.494	0.505
E40-E46 Malnutrition	0.001	0.511	0.488
E14 Unspecified diabetes mellitus	0.000	0.528	0.472
E04 Other non-toxic goitre	0.000	0.543	0.457
E07.8 Other specified disorders of thyroid	0.000	0.552	0.447
E55.9 Vitamin D deficiency, unspecified	0.000	0.554	0.446
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.560	0.440
E14.3 With ophthalmic complications	0.000	0.584	0.416
K90.9 Intestinal malabsorption, unspecified	0.000	0.585	0.415
M07 Psoriatic and enteropathic arthropathies	0.411	0.589	0.000
E55.0 Rickets, active	0.000	0.596	0.404
E13.8 With unspecified complications	0.000	0.599	0.401
E13.7 With multiple complications	0.000	0.599	0.401
E13.6 With other specified complications	0.000	0.599	0.401
E13.5 With peripheral circulatory complications	0.000	0.599	0.401
E13.4 With neurological complications	0.000	0.599	0.401
E13.3 With ophthalmic complications	0.000	0.599	0.401
E13.2 With renal complications	0.000	0.599	0.401
E13.1 With ketoacidosis	0.000	0.599	0.401
E13.0 With coma	0.000	0.599	0.401
E53.9 Vitamin B deficiency, unspecified	0.000	0.608	0.392
K90.3 Pancreatic steatorrhoea	0.000	0.624	0.376
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.624	0.376
K90.1 Tropical sprue	0.000	0.624	0.376
E50.9 Vitamin A deficiency, unspecified	0.000	0.625	0.374
E50.8 Other manifestations of vitamin A deficiency	0.000	0.625	0.374
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.625	0.374
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.625	0.374
E50.5 Vitamin A deficiency with night blindness	0.000	0.625	0.374
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.625	0.374
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.625	0.374
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.625	0.374
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.625	0.374
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.625	0.374
E51.9 Thiamine deficiency, unspecified	0.000	0.625	0.374
E51.8 Other manifestations of thiamine deficiency	0.000	0.625	0.374
E51.2 Wernicke's encephalopathy	0.000	0.625	0.374
E51.1 Beriberi	0.000	0.625	0.374
E56.9 Vitamin deficiency, unspecified	0.000	0.625	0.374
E56.8 Deficiency of other vitamins	0.000	0.625	0.374
E56.1 Deficiency of vitamin K	0.000	0.625	0.374
E56.0 Deficiency of vitamin E	0.000	0.625	0.374
E63.9 Nutritional deficiency, unspecified	0.000	0.625	0.374
E63.8 Other specified nutritional deficiencies	0.000	0.625	0.374
E63.1 Imbalance of constituents of food intake	0.000	0.625	0.374
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.625	0.374
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.625	0.374
E64.8 Sequelae of other nutritional deficiencies	0.000	0.625	0.374
E64.3 Sequelae of rickets	0.000	0.625	0.374
E64.2 Sequelae of vitamin C deficiency	0.000	0.625	0.374
E64.1 Sequelae of vitamin A deficiency	0.000	0.625	0.374
E64.0 Sequelae of protein-energy malnutrition	0.000	0.625	0.374
E61.2 Magnesium deficiency	0.000	0.629	0.371
E53.1 Pyridoxine deficiency	0.000	0.631	0.369
E53.0 Riboflavin deficiency	0.000	0.631	0.369
E67 Other hyperalimentation	0.000	0.631	0.369
E68 Sequelae of hyperalimentation	0.000	0.631	0.369
E61.9 Deficiency of nutrient element, unspecified	0.000	0.636	0.364
E61.8 Deficiency of other specified nutrient elements	0.000	0.636	0.364
E61.7 Deficiency of multiple nutrient elements	0.000	0.636	0.364
E61.6 Vanadium deficiency	0.000	0.636	0.364
E61.5 Molybdenum deficiency	0.000	0.636	0.364
E61.4 Chromium deficiency	0.000	0.636	0.364
E61.3 Manganese deficiency	0.000	0.636	0.364
E61.0 Copper deficiency	0.000	0.636	0.364
E04.9 Non-toxic goitre, unspecified	0.000	0.639	0.361
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.649	0.350
E45 Retarded development following protein-energy malnutrition	0.001	0.649	0.350
E43 Unspecified severe protein-energy malnutrition	0.001	0.649	0.350
E42 Marasmic kwashiorkor	0.001	0.649	0.350
E41 Nutritional marasmus	0.001	0.649	0.350
E40 Kwashiorkor	0.001	0.649	0.350
E61.1 Iron deficiency	0.000	0.658	0.342
E14.7 With multiple complications	0.000	0.662	0.338
E14.6 With other specified complications	0.000	0.662	0.338
E14.2 Withrenal complications	0.000	0.662	0.338
E14.0 With coma	0.000	0.662	0.338
E53.8 Deficiency of other specified B group vitamins	0.000	0.667	0.333
E14.1 With ketoacidosis	0.000	0.668	0.332
E04.8 Other specified non-toxic goitre	0.000	0.672	0.328
E14.8 With unspecified complications	0.000	0.676	0.323
E14.5 With peripheral circulatory complications	0.000	0.695	0.305
E66 Obesity	0.000	0.702	0.297
M07.6 Other enteropathic arthropathies	0.295	0.705	0.000
M07.5 Arthropathy in ulcerative colitis	0.295	0.705	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.295	0.705	0.000
M07.2 Psoriatic spondylitis	0.295	0.705	0.000
M07.1 Arthritis mutilans	0.295	0.705	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.295	0.705	0.000
E65 Localised adiposity	0.000	0.711	0.288
E04.0 Non-toxic diffuse goitre	0.000	0.721	0.279
E66.8 Other obesity	0.000	0.724	0.276
E14.4 With neurological complications	0.000	0.726	0.273
E67.8 Other specified hyperalimentation	0.000	0.735	0.264
E67.3 Hypervitaminosis D	0.000	0.735	0.264
E67.2 Megavitamin-B6 syndrome	0.000	0.735	0.264
E67.1 Hypercarotenaemia	0.000	0.735	0.264
E67.0 Hypervitaminosis A	0.000	0.735	0.264
E04.2 Non-toxic multinodular goitre	0.000	0.742	0.258
K90.8 Other intestinal malabsorption	0.001	0.744	0.255
E13.9 Without complications	0.001	0.744	0.255
E44.1 Mild protein-energy malnutrition	0.001	0.748	0.251
E44.0 Moderate protein-energy malnutrition	0.001	0.748	0.251
E20-E35 Disorders of other endocrine glands	0.000	0.760	0.240
L40-L45 Papulosquamous disorders	0.225	0.774	0.000
E27 Other disorders of adrenal gland	0.000	0.784	0.216
E66.1 Drug-induced obesity	0.000	0.786	0.213
E27.1 Primary adrenocortical insufficiency	0.000	0.787	0.213
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.211	0.788	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.211	0.788	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.211	0.788	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.211	0.788	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.211	0.788	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.211	0.788	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.211	0.788	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.211	0.788	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.211	0.788	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.211	0.788	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.211	0.788	0.000
M07.18 Arthritis mutilans (Other)	0.211	0.788	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.211	0.788	0.000
M07.16 Arthritis mutilans (Lower leg)	0.211	0.788	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.211	0.788	0.000
M07.14 Arthritis mutilans (Hand)	0.211	0.788	0.000
M07.13 Arthritis mutilans (Forearm)	0.211	0.788	0.000
M07.12 Arthritis mutilans (Upper arm)	0.211	0.788	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.211	0.788	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.211	0.788	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.211	0.788	0.000
M07.28 Psoriatic spondylitis (Other)	0.211	0.788	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.211	0.788	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.211	0.788	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.211	0.788	0.000
M07.24 Psoriatic spondylitis (Hand)	0.211	0.788	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.211	0.788	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.211	0.788	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.211	0.788	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.211	0.788	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.211	0.788	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.211	0.788	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.211	0.788	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.211	0.788	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.211	0.788	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.211	0.788	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.211	0.788	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.211	0.788	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.211	0.788	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.211	0.788	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.211	0.788	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.211	0.788	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.211	0.788	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.211	0.788	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.211	0.788	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.211	0.788	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.211	0.788	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.211	0.788	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.211	0.788	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.211	0.788	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.211	0.788	0.000
M07.68 Other enteropathic arthropathies (Other)	0.211	0.788	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.211	0.788	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.211	0.788	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.211	0.788	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.211	0.788	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.211	0.788	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.211	0.788	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.211	0.788	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.211	0.788	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.792	0.208
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.818	0.182
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.826	0.174
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.827	0.172
E32 Diseases of thymus	0.000	0.827	0.172
E31 Polyglandular dysfunction	0.000	0.827	0.172
E30 Disorders of puberty, not elsewhere classified	0.000	0.827	0.172
E25 Adrenogenital disorders	0.000	0.827	0.172
E34 Other endocrine disorders	0.000	0.831	0.169
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.167	0.833	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.164	0.836	0.000
E29 Testicular dysfunction	0.000	0.836	0.163
E20 Hypoparathyroidism	0.000	0.837	0.163
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.162	0.838	0.000
L44 Other papulosquamous disorders	0.162	0.838	0.000
L41 Parapsoriasis	0.162	0.838	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.162	0.838	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.839	0.161
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.160	0.840	0.000
E66.0 Obesity due to excess calories	0.000	0.842	0.158
L42 Pityriasis rosea	0.156	0.843	0.000
E26 Hyperaldosteronism	0.000	0.844	0.156
E27.5 Adrenomedullary hyperfunction	0.000	0.845	0.155
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.845	0.155
E27.0 Other adrenocortical overactivity	0.000	0.845	0.155
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.153	0.847	0.000
T43.2 Other and unspecified antidepressants	0.151	0.849	0.000
E24 Cushing's syndrome	0.000	0.852	0.148
E22 Hyperfunction of pituitary gland	0.000	0.852	0.148
E27.2 Addisonian crisis	0.000	0.855	0.145
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.145	0.855	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.142	0.858	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.142	0.858	0.000
E28 Ovarian dysfunction	0.000	0.859	0.141
T43.4 Butyrophenone and thioxanthene neuroleptics	0.140	0.860	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.138	0.862	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.864	0.134
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.135	0.865	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.867	0.133
T43.6 Psychostimulants with abuse potential	0.131	0.869	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.129	0.871	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.127	0.873	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.126	0.874	0.000
E34.0 Carcinoid syndrome	0.000	0.874	0.126
T50.9 Other and unspecified drugs, medicaments and biological substances	0.126	0.874	0.000
T36 Poisoning by systemic antibiotics	0.124	0.876	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.876	0.124
E25.8 Other adrenogenital disorders	0.000	0.876	0.124
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.876	0.124
E30.9 Disorder of puberty, unspecified	0.000	0.876	0.124
E30.8 Other disorders of puberty	0.000	0.876	0.124
E30.1 Precocious puberty	0.000	0.876	0.124
E30.0 Delayed puberty	0.000	0.876	0.124
E31.9 Polyglandular dysfunction, unspecified	0.000	0.876	0.124
E31.8 Other polyglandular dysfunction	0.000	0.876	0.124
E31.1 Polyglandular hyperfunction	0.000	0.876	0.124
E31.0 Autoimmune polyglandular failure	0.000	0.876	0.124
E32.9 Disease of thymus, unspecified	0.000	0.876	0.124
E32.8 Other diseases of thymus	0.000	0.876	0.124
E32.1 Abscess of thymus	0.000	0.876	0.124
E32.0 Persistent hyperplasia of thymus	0.000	0.876	0.124
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.876	0.124
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.876	0.124
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.876	0.124
T46 Poisoning by agents primarily affecting the cardiovascular system	0.122	0.878	0.000
E34.5 Androgen resistance syndrome	0.000	0.879	0.121
E34.4 Constitutional tall stature	0.000	0.879	0.121
E34.3 Short stature, not elsewhere classified	0.000	0.879	0.121
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.879	0.121
E34.1 Other hypersecretion of intestinal hormones	0.000	0.879	0.121
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.120	0.880	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.120	0.880	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.120	0.880	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.120	0.880	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.120	0.880	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.120	0.880	0.000
T44.0 Anticholinesterase agents	0.120	0.880	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.119	0.881	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.119	0.881	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.118	0.882	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.118	0.882	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.118	0.882	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.118	0.882	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.883	0.117
E29.8 Other testicular dysfunction	0.000	0.883	0.117
E29.0 Testicular hyperfunction	0.000	0.883	0.117
E22.1 Hyperprolactinaemia	0.000	0.883	0.117
E20.8 Other hypoparathyroidism	0.000	0.883	0.117
E20.1 Pseudohypoparathyroidism	0.000	0.883	0.117
E20.0 Idiopathic hypoparathyroidism	0.000	0.883	0.117
T43.9 Psychotropic drug, unspecified	0.116	0.883	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.116	0.883	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.116	0.883	0.000
L41.9 Parapsoriasis, unspecified	0.116	0.884	0.000
L41.8 Other parapsoriasis	0.116	0.884	0.000
L41.5 Retiform parapsoriasis	0.116	0.884	0.000
L41.4 Large plaque parapsoriasis	0.116	0.884	0.000
L41.3 Small plaque parapsoriasis	0.116	0.884	0.000
L41.2 Lymphomatoid papulosis	0.116	0.884	0.000
L41.1 Pityriasis lichenoides chronica	0.116	0.884	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.116	0.884	0.000
L44.9 Papulosquamous disorder, unspecified	0.116	0.884	0.000
L44.8 Other specified papulosquamous disorders	0.116	0.884	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.116	0.884	0.000
L44.3 Lichen ruber moniliformis	0.116	0.884	0.000
L44.2 Lichen striatus	0.116	0.884	0.000
L44.1 Lichen nitidus	0.116	0.884	0.000
L44.0 Pityriasis rubra pilaris	0.116	0.884	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.114	0.885	0.000
T47.4 Other laxatives	0.113	0.887	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.888	0.112
E26.8 Other hyperaldosteronism	0.000	0.888	0.112
E26.1 Secondary hyperaldosteronism	0.000	0.888	0.112
E29.1 Testicular hypofunction	0.000	0.892	0.108
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.893	0.107
E24.2 Drug-induced Cushing's syndrome	0.000	0.893	0.107
E20.9 Hypoparathyroidism, unspecified	0.000	0.893	0.107
E24.8 Other Cushing's syndrome	0.000	0.894	0.106
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.894	0.106
E24.3 Ectopic ACTH syndrome	0.000	0.894	0.106
E24.1 Nelson's syndrome	0.000	0.894	0.106
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.894	0.106
E22.8 Other hyperfunction of pituitary gland	0.000	0.894	0.106
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.104	0.896	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.104	0.896	0.000
T47.7 Emetics	0.104	0.896	0.000
T47.6 Antidiarrhoeal drugs	0.104	0.896	0.000
T47.5 Digestants	0.104	0.896	0.000
T47.3 Saline and osmotic laxatives	0.104	0.896	0.000
T47.2 Stimulant laxatives	0.104	0.896	0.000
T47.0 Histamine H(2)-receptor antagonists	0.104	0.896	0.000
T50.8 Diagnostic agents	0.102	0.898	0.000
T50.7 Analeptics and opioid receptor antagonists	0.102	0.898	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.102	0.898	0.000
T50.5 Appetite depressants	0.102	0.898	0.000
T50.4 Drugs affecting uric acid metabolism	0.102	0.898	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.102	0.898	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.102	0.898	0.000
T50.1 Loop [high-ceiling] diuretics	0.102	0.898	0.000
T50.0 Mineralocorticoids and their antagonists	0.102	0.898	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.898	0.101
E28.8 Other ovarian dysfunction	0.000	0.898	0.101
E28.1 Androgen excess	0.000	0.898	0.101
E28.0 Oestrogen excess	0.000	0.898	0.101
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.101	0.899	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.099	0.901	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.099	0.901	0.000
T42.3 Barbiturates	0.099	0.901	0.000
T42.2 Succinimides and oxazolidinediones	0.099	0.901	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.099	0.901	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.901	0.099
E28.3 Primary ovarian failure	0.000	0.902	0.098
T45.0 Antiallergic and antiemetic drugs	0.097	0.903	0.000
T38.1 Thyroid hormones and substitutes	0.097	0.903	0.000
E27.9 Disorder of adrenal gland, unspecified	0.001	0.904	0.096
T42.0 Hydantoin derivatives	0.096	0.904	0.000
T36.0 Penicillins	0.096	0.904	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.904	0.095
E26.0 Primary hyperaldosteronism	0.000	0.905	0.095
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.906	0.094
T42.1 Iminostilbenes	0.094	0.906	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.094	0.906	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.907	0.093
E23 Hypofunction and other disorders of pituitary gland	0.000	0.907	0.093
T38.9 Other and unspecified hormone antagonists	0.093	0.907	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.093	0.907	0.000
T38.7 Androgens and anabolic congeners	0.093	0.907	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.093	0.907	0.000
T38.5 Other oestrogens and progestogens	0.093	0.907	0.000
T38.4 Oral contraceptives	0.093	0.907	0.000
T38.2 Antithyroid drugs	0.093	0.907	0.000
T38.0 Glucocorticoids and synthetic analogues	0.093	0.907	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.093	0.907	0.000
E34.8 Other specified endocrine disorders	0.000	0.907	0.092
T46.5 Other antihypertensive drugs, not elsewhere classified	0.092	0.908	0.000
T36.9 Systemic antibiotic, unspecified	0.089	0.911	0.000
T36.8 Other systemic antibiotics	0.089	0.911	0.000
T36.7 Antifungal antibiotics, systemically used	0.089	0.911	0.000
T36.6 Rifamycins	0.089	0.911	0.000
T36.5 Aminoglycosides	0.089	0.911	0.000
T36.4 Tetracyclines	0.089	0.911	0.000
T36.3 Macrolides	0.089	0.911	0.000
T36.2 Chloramphenicol group	0.089	0.911	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.089	0.911	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.089	0.911	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.088	0.912	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.088	0.912	0.000
T46.7 Peripheral vasodilators	0.088	0.912	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.088	0.912	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.088	0.912	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.088	0.912	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.085	0.915	0.000
T45.8 Other primarily systemic and haematological agents	0.085	0.915	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.085	0.915	0.000
T45.6 Fibrinolysis-affecting drugs	0.085	0.915	0.000
T45.4 Iron and its compounds	0.085	0.915	0.000
T45.3 Enzymes, not elsewhere classified	0.085	0.915	0.000
T45.2 Vitamins, not elsewhere classified	0.085	0.915	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.085	0.915	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.085	0.915	0.000
T37.5 Antiviral drugs	0.085	0.915	0.000
T37.4 Anthelminthics	0.085	0.915	0.000
T37.3 Other antiprotozoal drugs	0.085	0.915	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.085	0.915	0.000
T37.1 Antimycobacterial drugs	0.085	0.915	0.000
T37.0 Sulphonamides	0.085	0.915	0.000
T41.5 Therapeutic gases	0.085	0.915	0.000
T41.4 Anaesthetic, unspecified	0.085	0.915	0.000
T41.3 Local anaesthetics	0.085	0.915	0.000
T41.2 Other and unspecified general anaesthetics	0.085	0.915	0.000
T41.1 Intravenous anaesthetics	0.085	0.915	0.000
T41.0 Inhaled anaesthetics	0.085	0.915	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.085	0.915	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.085	0.915	0.000
T48.5 Anti-common-cold drugs	0.085	0.915	0.000
T48.4 Expectorants	0.085	0.915	0.000
T48.3 Antitussives	0.085	0.915	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.085	0.915	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.085	0.915	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations