TreeWAS – Variant ID: rs1363605

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C43.5 Malignant melanoma of trunk	0.000	0.975	0.025
E86 Volume depletion	0.015	0.985	0.000
E10.1 With ketoacidosis	0.010	0.990	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.992	0.008
C43 Malignant melanoma of skin	0.000	0.992	0.008
S22.4 Multiple fractures of ribs	0.000	0.993	0.007
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.993	0.007
C43.9 Malignant melanoma of skin, unspecified	0.000	0.993	0.006
C71.9 Brain, unspecified	0.000	0.994	0.006
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.994	0.006
C43.4 Malignant melanoma of scalp and neck	0.000	0.994	0.006
S22.20 Fracture of sternum (closed)	0.000	0.994	0.006
Z04.8 Examination and observation for other specified reasons	0.006	0.994	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.994	0.006
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.994	0.006
C43.0 Malignant melanoma of lip	0.000	0.994	0.006
S22.2 Fracture of sternum	0.000	0.994	0.006
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.994	0.006
Y40.8 Other systemic antibiotics	0.005	0.995	0.000
S80.9 Superficial injury of lower leg, unspecified	0.005	0.995	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.000	0.995	0.005
S22.41 Multiple fractures of ribs (open)	0.000	0.995	0.005
C71.2 Temporal lobe	0.000	0.995	0.005
K70.3 Alcoholic cirrhosis of liver	0.000	0.995	0.005
M41.99 Scoliosis, unspecified (Site unspecified)	0.005	0.995	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.995	0.005
S22.5 Flail chest	0.000	0.995	0.004
E10.3 With ophthalmic complications	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.000	0.996	0.004
S22.21 Fracture of sternum (open)	0.000	0.996	0.004
S22.9 Fracture of bony thorax, part unspecified	0.000	0.996	0.004
S22.8 Fracture of other parts of bony thorax	0.000	0.996	0.004
Z73 Problems related to life-management difficulty	0.004	0.996	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.996	0.004
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
S22.3 Fracture of rib	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.000	0.996	0.004
C71.3 Parietal lobe	0.000	0.996	0.004
C71.1 Frontal lobe	0.000	0.996	0.004
C71.7 Brain stem	0.000	0.996	0.004
C71.6 Cerebellum	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.000	0.996	0.004
Z71.8 Other specified counselling	0.004	0.996	0.000
S80 Superficial injury of lower leg	0.004	0.996	0.000
Y40 Systemic antibiotics	0.004	0.996	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.996	0.004
C71.4 Occipital lobe	0.000	0.996	0.004
E10.2 With renal complications	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.000	0.996	0.004
Y40.0 Penicillins	0.004	0.996	0.000
S80.7 Multiple superficial injuries of lower leg	0.004	0.996	0.000
Z73.8 Other problems related to life-management difficulty	0.004	0.996	0.000
S80.0 Contusion of knee	0.004	0.996	0.000
Z73.6 Limitation of activities due to disability	0.004	0.996	0.000
S80.8 Other superficial injuries of lower leg	0.004	0.996	0.000
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
Z75.5 Holiday relief care	0.004	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
S22.51 Flail chest (open)	0.000	0.996	0.003
E10.8 With unspecified complications	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
Z75 Problems related to medical facilities and other health care	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.003
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.003
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.003
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.003
Z73.5 Social role conflict, not elsewhere classified	0.003	0.997	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.003	0.997	0.000
Z73.2 Lack of relaxation and leisure	0.003	0.997	0.000
Z73.1 Accentuation of personality traits	0.003	0.997	0.000
Z73.0 Burn-out	0.003	0.997	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.003
E10.7 With multiple complications	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.000	0.997	0.003
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
S22.30 Fracture of rib (closed)	0.000	0.997	0.003
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
K62.9 Disease of anus and rectum, unspecified	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.003
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
O43.8 Other placental disorders	0.000	0.997	0.003
Y57.6 Other diagnostic agents	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.997	0.003
K70 Alcoholic liver disease	0.000	0.997	0.003
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
Y57.5 X-ray contrast media	0.003	0.997	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.003	0.997	0.000
Z75.2 Other waiting period for investigation and treatment	0.003	0.997	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.003	0.997	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
Z73.3 Stress, not elsewhere classified	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
H35.5 Hereditary retinal dystrophy	0.003	0.997	0.000
Z71.6 Tobacco abuse counselling	0.003	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.003	0.997	0.000
Z75.0 Medical services not available in home	0.003	0.997	0.000
Z71.9 Counselling, unspecified	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.997	0.000
Z75.8 Other problems related to medical facilities and other health care	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.002	0.998	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.998	0.002
Z71.7 Human immunodeficiency virus [HIV] counselling	0.002	0.998	0.000
Z71.5 Drug abuse counselling and surveillance	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.002	0.998	0.000
Z71.0 Person consulting on behalf of another person	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
E10.4 With neurological complications	0.002	0.998	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.000	0.998	0.002
D39.1 Ovary	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.000	0.998	0.002
Z74.8 Other problems related to care-provider dependency	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
H35.6 Retinal haemorrhage	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
Z74.1 Need for assistance with personal care	0.002	0.998	0.000
H35.7 Separation of retinal layers	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
K70.4 Alcoholic hepatic failure	0.000	0.998	0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.002	0.998	0.000
Z74.3 Need for continuous supervision	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
Z71.2 Person consulting for explanation of investigation findings	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.000	0.998	0.002
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
M45.X6 Ankylosing spondylitis (Lumbar region)	0.002	0.998	0.000
O43.1 Malformation of placenta	0.000	0.998	0.002
Z70.9 Sex counselling, unspecified	0.002	0.998	0.000
Z70.8 Other sex counselling	0.002	0.998	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.002	0.998	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.002	0.998	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.002	0.998	0.000
Z70.0 Counselling related to sexual attitude	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
H35 Other retinal disorders	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Z76 Persons encountering health services in other circumstances	0.002	0.998	0.000
Z74.0 Reduced mobility	0.002	0.998	0.000
M45 Ankylosing spondylitis	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.002	0.998	0.000
O43 Placental disorders	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.998	0.002
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O14.2 HELLP syndrome	0.000	0.998	0.002
H52.1 Myopia	0.000	0.998	0.002
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.998	0.000
Y43.2 Antineoplastic natural products	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
M41.5 Other secondary scoliosis	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
H36.0 Diabetic retinopathy	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.002	0.998	0.000
H91.9 Hearing loss, unspecified	0.002	0.998	0.000
J94.2 Haemothorax	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.000	0.998	0.002
S70.0 Contusion of hip	0.000	0.998	0.002
Y53.4 Other laxatives	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
H35.1 Retinopathy of prematurity	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.002	0.998	0.000
Z76.5 Malingerer [conscious situation]	0.001	0.998	0.000
Z76.4 Other boarder in health-care facility	0.001	0.998	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.001	0.998	0.000
Z76.1 Health supervision and care of foundling	0.001	0.998	0.000
Z76.0 Issue of repeat prescription	0.001	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.002	0.998	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.002	0.998	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.002	0.998	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.002	0.998	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y41.4 Anthelminthics	0.001	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.001	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
Y41.1 Antimycobacterial drugs	0.001	0.998	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.998	0.002
H91 Other hearing loss	0.002	0.998	0.000
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
O43.9 Placental disorder, unspecified	0.000	0.998	0.002
O43.2 Morbidly adherent placenta	0.000	0.998	0.002
O43.0 Placental transfusion syndromes	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.001	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.001	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Z52.3 Bone marrow donor	0.002	0.998	0.000
O15 Eclampsia	0.000	0.998	0.001
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.998	0.001
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
D43.2 Brain, unspecified	0.000	0.998	0.002
Y41.0 Sulphonamides	0.001	0.998	0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.998	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.998	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.998	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.998	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.998	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.998	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.998	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.998	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.998	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.998	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.998	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.998	0.000
Z76.3 Healthy person accompanying sick person	0.001	0.998	0.000
D12.6 Colon, unspecified	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
J94 Other pleural conditions	0.000	0.998	0.002
H54.6 Unqualified visual loss, one eye	0.001	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.001	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.001	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.998	0.000
M16.7 Other secondary coxarthrosis	0.002	0.998	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.001	0.998	0.000
Y46.4 Iminostilbenes	0.001	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
H35.2 Other proliferative retinopathy	0.001	0.998	0.000
Y48.5 Therapeutic gases	0.001	0.998	0.000
Y48.1 Parenteral anaesthetics	0.001	0.998	0.000
Y48.0 Inhaled anaesthetics	0.001	0.998	0.000
H35.8 Other specified retinal disorders	0.001	0.999	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.999	0.000
H54.2 Low vision, both eyes	0.001	0.999	0.000
H54.1 Blindness, one eye, low vision, other eye	0.001	0.999	0.000
H91.2 Sudden idiopathic hearing loss	0.001	0.999	0.000
H91.0 Ototoxic hearing loss	0.001	0.999	0.000
T85.2 Mechanical complication of intraocular lens	0.001	0.999	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.001	0.999	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.000	0.999	0.001
O15.2 Eclampsia in the puerperium	0.000	0.999	0.001
O15.1 Eclampsia in labour	0.000	0.999	0.001
O15.0 Eclampsia in pregnancy	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
S20-S29 Injuries to the thorax	0.000	0.999	0.001
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.999	0.001
D13.1 Stomach	0.000	0.999	0.001
N48.0 Leukoplakia of penis	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.999	0.000
Y42.4 Oral contraceptives	0.001	0.999	0.000
Y42.2 Antithyroid drugs	0.001	0.999	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.999	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.999	0.001
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
H47.7 Disorder of visual pathways, unspecified	0.001	0.999	0.000
H47.6 Disorders of visual cortex	0.001	0.999	0.000
H47.5 Disorders of other visual pathways	0.001	0.999	0.000
H47.4 Disorders of optic chiasm	0.001	0.999	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.999	0.001
Y45.2 Propionic acid derivatives	0.001	0.999	0.000
H36 Retinal disorders in diseases classified elsewhere	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
H92.2 Otorrhagia	0.001	0.999	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.999	0.000
H92 Otalgia and effusion of ear	0.001	0.999	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.999	0.001
H91.1 Presbycusis	0.001	0.999	0.000
H93.8 Other specified disorders of ear	0.001	0.999	0.000
J94.9 Pleural condition, unspecified	0.000	0.999	0.001
J94.0 Chylous effusion	0.000	0.999	0.001
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.999	0.000
Y44.7 Plasma substitutes	0.001	0.999	0.000
Y44.6 Natural blood and blood products	0.001	0.999	0.000
Y44.5 Thrombolytic drugs	0.001	0.999	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.999	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.999	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.999	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.999	0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.001	0.999	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.999	0.001
J94.1 Fibrothorax	0.000	0.999	0.001
M62.80 Other specified disorders of muscle (Multiple sites)	0.001	0.999	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.999	0.001
N94.6 Dysmenorrhoea, unspecified	0.001	0.999	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations