TreeWAS – Variant ID: rs1382879

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.996	0.004	0.000
E03 Other hypothyroidism	0.634	0.366	0.000
E03.8 Other specified hypothyroidism	0.535	0.465	0.000
E03.1 Congenital hypothyroidism without goitre	0.495	0.504	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.474	0.526	0.000
E03.5 Myxoedema coma	0.455	0.545	0.000
E03.4 Atrophy of thyroid (acquired)	0.455	0.545	0.000
E03.3 Postinfectious hypothyroidism	0.455	0.545	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.436	0.564	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.054	0.946	0.000
S52.6 Fracture of lower end of both ulna and radius	0.021	0.979	0.000
E00-E07 Disorders of thyroid gland	0.020	0.980	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.986	0.000
E00 Congenital iodine-deficiency syndrome	0.014	0.986	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.013	0.987	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.012	0.988	0.000
E07 Other disorders of thyroid	0.012	0.988	0.000
C18.2 Ascending colon	0.011	0.989	0.000
E06 Thyroiditis	0.011	0.989	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.010	0.989	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.010	0.989	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.010	0.989	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.010	0.989	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.010	0.989	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.010	0.989	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.010	0.989	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.010	0.989	0.000
D39.1 Ovary	0.009	0.991	0.000
E07.1 Dyshormogenetic goitre	0.009	0.991	0.000
E07.0 Hypersecretion of calcitonin	0.009	0.991	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.009	0.991	0.000
D47.1 Chronic myeloproliferative disease	0.009	0.991	0.000
E07.8 Other specified disorders of thyroid	0.008	0.991	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.008	0.992	0.000
E06.1 Subacute thyroiditis	0.008	0.992	0.000
E06.4 Drug-induced thyroiditis	0.008	0.992	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.008	0.992	0.000
E06.0 Acute thyroiditis	0.008	0.992	0.000
E06.5 Other chronic thyroiditis	0.008	0.992	0.000
E07.9 Disorder of thyroid, unspecified	0.008	0.992	0.000
S83.2 Tear of meniscus, current	0.008	0.992	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.992	0.008
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.007	0.993	0.000
E06.9 Thyroiditis, unspecified	0.007	0.993	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
I95.1 Orthostatic hypotension	0.000	0.993	0.007
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.006	0.993	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.006	0.994	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.006	0.994	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.006	0.994	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.006	0.994	0.000
E06.3 Autoimmune thyroiditis	0.006	0.994	0.000
C18.6 Descending colon	0.006	0.994	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.994	0.006
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.006	0.994	0.000
D45 Polycythaemia vera	0.006	0.994	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.006	0.994	0.000
D39.9 Female genital organ, unspecified	0.005	0.994	0.000
D39.2 Placenta	0.005	0.994	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.005	0.995	0.000
C18 Malignant neoplasm of colon	0.005	0.995	0.000
D44.8 Pluriglandular involvement	0.005	0.995	0.000
D75.1 Secondary polycythaemia	0.005	0.995	0.000
D43.2 Brain, unspecified	0.005	0.995	0.000
D39.0 Uterus	0.005	0.995	0.000
D47.4 Osteomyelofibrosis	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
D39.7 Other female genital organs	0.005	0.995	0.000
D46 Myelodysplastic syndromes	0.005	0.995	0.000
D44.1 Adrenal gland	0.005	0.995	0.000
E05.8 Other thyrotoxicosis	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.000	0.995	0.005
C18.1 Appendix	0.005	0.995	0.000
E05.5 Thyroid crisis or storm	0.005	0.995	0.000
E05.4 Thyrotoxicosis factitia	0.005	0.995	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.005	0.995	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.995	0.005
C80 Malignant neoplasm without specification of site	0.000	0.995	0.005
D43.4 Spinal cord	0.005	0.995	0.000
D43.0 Brain, supratentorial	0.005	0.995	0.000
F43.0 Acute stress reaction	0.005	0.995	0.000
C18.0 Caecum	0.005	0.995	0.000
D44.9 Endocrine gland, unspecified	0.004	0.995	0.000
D47.2 Monoclonal gammopathy	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.995	0.005
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.995	0.005
D44.7 Aortic body and other paraganglia	0.004	0.995	0.000
D44.5 Pineal gland	0.004	0.996	0.000
D44.2 Parathyroid gland	0.004	0.996	0.000
D44.6 Carotid body	0.004	0.996	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.004	0.996	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.996	0.004
D44.0 Thyroid gland	0.004	0.996	0.000
D43.9 Central nervous system, unspecified	0.004	0.996	0.000
D43.7 Other parts of central nervous system	0.004	0.996	0.000
D43.3 Cranial nerves	0.004	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.004
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.004	0.996	0.000
C18.8 Overlapping lesion of colon	0.004	0.996	0.000
D46.2 Refractory anaemia with excess of blasts	0.004	0.996	0.000
D44.4 Craniopharyngeal duct	0.004	0.996	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
I95.2 Hypotension due to drugs	0.000	0.996	0.004
D46.5 Refractory anaemia with multi-lineage dysplasia	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.996	0.004
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.004	0.996	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.004	0.996	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.004	0.996	0.000
D46.4 Refractory anaemia, unspecified	0.004	0.996	0.000
S52.00 Fracture of upper end of ulna (closed)	0.004	0.996	0.000
D38.0 Larynx	0.004	0.996	0.000
M25.50 Pain in joint (Multiple sites)	0.004	0.996	0.000
D46.7 Other myelodysplastic syndromes	0.004	0.996	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.996	0.004
J93.9 Pneumothorax, unspecified	0.000	0.996	0.004
D40.7 Other male genital organs	0.004	0.996	0.000
D44.3 Pituitary gland	0.004	0.996	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.996	0.004
E27.0 Other adrenocortical overactivity	0.000	0.996	0.004
D42.9 Meninges, unspecified	0.004	0.996	0.000
D42.1 Spinal meninges	0.004	0.996	0.000
D42.0 Cerebral meninges	0.004	0.996	0.000
D46.1 Refractory anaemia with sideroblasts	0.004	0.996	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.996	0.004
E27.2 Addisonian crisis	0.000	0.996	0.004
I95 Hypotension	0.000	0.996	0.004
D43.1 Brain, infratentorial	0.003	0.996	0.000
D40.9 Male genital organ, unspecified	0.003	0.997	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.003	0.997	0.000
D38.6 Respiratory organ, unspecified	0.003	0.997	0.000
D38.4 Thymus	0.003	0.997	0.000
D38.2 Pleura	0.003	0.997	0.000
D40.0 Prostate	0.003	0.997	0.000
C18.3 Hepatic flexure	0.003	0.997	0.000
D38.3 Mediastinum	0.003	0.997	0.000
S52 Fracture of forearm	0.003	0.997	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.997	0.003
S52.0 Fracture of upper end of ulna	0.003	0.997	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
C18.9 Colon, unspecified	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
C17.2 Ileum	0.003	0.997	0.000
D38.5 Other respiratory organs	0.003	0.997	0.000
C45.9 Mesothelioma, unspecified	0.000	0.997	0.003
C18.7 Sigmoid colon	0.003	0.997	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
C18.4 Transverse colon	0.003	0.997	0.000
D75 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
J93 Pneumothorax	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
C17.1 Jejunum	0.003	0.997	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.003	0.997	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.997	0.003
C17 Malignant neoplasm of small intestine	0.003	0.997	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.003	0.997	0.000
S52.9 Fracture of forearm, part unspecified	0.002	0.997	0.000
C45 Mesothelioma	0.000	0.997	0.003
D40.1 Testis	0.002	0.997	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.997	0.002
C17.9 Small intestine, unspecified	0.003	0.997	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.997	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
D38.1 Trachea, bronchus and lung	0.002	0.997	0.000
D41.2 Ureter	0.002	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.998	0.002
D48.7 Other specified sites	0.002	0.998	0.000
I95.8 Other hypotension	0.000	0.998	0.002
S52.2 Fracture of shaft of ulna	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.002	0.998	0.000
S52.3 Fracture of shaft of radius	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.000	0.998	0.002
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
M65.34 Trigger finger-Hand	0.002	0.998	0.000
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.998	0.002
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.998	0.002
D41.1 Renal pelvis	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
I95.0 Idiopathic hypotension	0.000	0.998	0.002
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
T79.8 Other early complications of trauma	0.002	0.998	0.000
C17.0 Duodenum	0.002	0.998	0.000
S52.21 Fracture of shaft of ulna (open)	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.002	0.998	0.000
C17.3 Meckel's diverticulum	0.002	0.998	0.000
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
C18.5 Splenic flexure	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.998	0.002
S52.41 Fracture of shafts of both ulna and radius (open)	0.002	0.998	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.002	0.998	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.000	0.998	0.002
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.002
F43.2 Adjustment disorders	0.002	0.998	0.000
C48.2 Peritoneum, unspecified	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
S52.31 Fracture of shaft of radius (open)	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.001	0.998	0.001
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
D16.4 Bones of skull and face	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
M43.0 Spondylolysis	0.000	0.998	0.002
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
S52.81 Fracture of other parts of forearm (open)	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
S52.71 Multiple fractures of forearm (open)	0.001	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.002	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000
N42.2 Atrophy of prostate	0.000	0.998	0.002
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
M65.3 Trigger finger	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.002	0.998	0.000
S52.30 Fracture of shaft of radius (closed)	0.001	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
J93.8 Other pneumothorax	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
M43.09 Spondylolysis (Site unspecified)	0.000	0.998	0.002
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.998	0.001
C43.7 Malignant melanoma of lower limb, including hip	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.998	0.002
M65.14 Other infective (teno)synovitis (Hand)	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.001	0.998	0.001
H44.0 Purulent endophthalmitis	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.998	0.002
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.998	0.002
M43.04 Spondylolysis (Thoracic region)	0.000	0.998	0.002
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.998	0.002
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.998	0.002
D48.6 Breast	0.002	0.998	0.000
F50.2 Bulimia nervosa	0.000	0.998	0.002
S52.5 Fracture of lower end of radius	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.002	0.998	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.002	0.998	0.000
T79.5 Traumatic anuria	0.002	0.998	0.000
F50 Eating disorders	0.000	0.998	0.002
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.002
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
K57.1 Diverticular disease of small intestine without perforation or abscess	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.002	0.998	0.000
C48.0 Retroperitoneum	0.000	0.998	0.002
D41.0 Kidney	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
F43.8 Other reactions to severe stress	0.001	0.998	0.000
H81.0 Meniere's disease	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
Y84.6 Urinary catheterisation	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.998	0.002
M65.39 Trigger finger-Site unspec	0.001	0.998	0.000
M65.38 Trigger finger-Other	0.001	0.998	0.000
M65.37 Trigger finger-Ankle/foot	0.001	0.998	0.000
M65.36 Trigger finger-Lower leg	0.001	0.998	0.000
M65.35 Trigger finger-Pelvic/thigh	0.001	0.998	0.000
M65.33 Trigger finger-Forearm	0.001	0.998	0.000
M65.32 Trigger finger-Upper arm	0.001	0.998	0.000
M65.31 Trigger finger-Shldr region	0.001	0.998	0.000
M65.30 Trigger finger-Mult sites	0.001	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.001	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.001
L12.0 Bullous pemphigoid	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.998	0.001
D36.0 Lymph nodes	0.002	0.998	0.000
F50.9 Eating disorder, unspecified	0.000	0.998	0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.998	0.002
M65.1 Other infective (teno)synovitis	0.001	0.998	0.000
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.998	0.002
H02.3 Blepharochalasis	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.000	0.998	0.002
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I98.0 Cardiovascular syphilis	0.000	0.998	0.001
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.998	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.001	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.001	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.998	0.000
D36 Benign neoplasm of other and unspecified sites	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.001	0.998	0.000
W44.0 Home	0.000	0.998	0.001
S52.20 Fracture of shaft of ulna (closed)	0.001	0.999	0.000
F50.8 Other eating disorders	0.000	0.999	0.001
F50.5 Vomiting associated with other psychological disturbances	0.000	0.999	0.001
F50.4 Overeating associated with other psychological disturbances	0.000	0.999	0.001
F50.3 Atypical bulimia nervosa	0.000	0.999	0.001
F50.1 Atypical anorexia nervosa	0.000	0.999	0.001
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.001	0.999	0.001
D37.2 Small intestine	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
S52.51 Fracture of lower end of radius (open)	0.001	0.999	0.000
H44.2 Degenerative myopia	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.000	0.999	0.001
I67.9 Cerebrovascular disease, unspecified	0.000	0.999	0.001
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.999	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.001	0.999	0.000
S54.0 Injury of ulnar nerve at forearm level	0.001	0.999	0.000
Y60.4 During endoscopic examination	0.001	0.999	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.001	0.999	0.000
C48.1 Specified parts of peritoneum	0.000	0.999	0.001
D16.5 Lower jaw bone	0.001	0.999	0.000
D36.9 Benign neoplasm of unspecified site	0.001	0.999	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.999	0.001
Z57.7 Occupational exposure to vibration	0.000	0.999	0.001
Z57.6 Occupational exposure to extreme temperature	0.000	0.999	0.001
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.999	0.001
Z57.1 Occupational exposure to radiation	0.000	0.999	0.001
Z57.0 Occupational exposure to noise	0.000	0.999	0.001
H44 Disorders of globe	0.001	0.999	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.001	0.999	0.000
M65.18 Other infective (teno)synovitis (Other)	0.001	0.999	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.001	0.999	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.001	0.999	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.001	0.999	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.001	0.999	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.001	0.999	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.001	0.999	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.001	0.999	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.999	0.001
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.999	0.001
C46 Kaposi's sarcoma	0.000	0.999	0.001
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
S06.4 Epidural haemorrhage	0.001	0.999	0.000
S09.9 Unspecified injury of head	0.001	0.999	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.000	0.999	0.001
M65 Synovitis and tenosynovitis	0.001	0.999	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.999	0.000
M89.9 Disorder of bone, unspecified	0.001	0.999	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.001	0.999	0.000
H44.4 Hypotony of eye	0.001	0.999	0.000
K06.0 Gingival recession	0.000	0.999	0.001
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.999	0.001
Y60.8 During other surgical and medical care	0.001	0.999	0.000
O41.1 Infection of amniotic sac and membranes	0.000	0.999	0.001
S06.1 Traumatic cerebral oedema	0.001	0.999	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.001	0.999	0.000
B18 Chronic viral hepatitis	0.000	0.999	0.001
M54.16 Radiculopathy (Lumbar region)	0.001	0.999	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
E88.2 Lipomatosis, not elsewhere classified	0.001	0.999	0.000
H44.5 Degenerated conditions of globe	0.001	0.999	0.000
I71.0 Dissection of aorta [any part]	0.001	0.999	0.000
M65.2 Calcific tendinitis	0.001	0.999	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
D16.2 Long bones of lower limb	0.001	0.999	0.000
H44.8 Other disorders of globe	0.001	0.999	0.000
H44.1 Other endophthalmitis	0.001	0.999	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.999	0.001
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.001	0.999	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.999	0.001
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.999	0.001
C46.7 Kaposi's sarcoma of other sites	0.000	0.999	0.001
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.999	0.001
C46.2 Kaposi's sarcoma of palate	0.000	0.999	0.001
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.999	0.001
C46.0 Kaposi's sarcoma of skin	0.000	0.999	0.001
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.999	0.001
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.999	0.001
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.999	0.001
C47.5 Peripheral nerves of pelvis	0.000	0.999	0.001
C47.4 Peripheral nerves of abdomen	0.000	0.999	0.001
C47.3 Peripheral nerves of thorax	0.000	0.999	0.001
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.999	0.001
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.999	0.001
C47.0 Peripheral nerves of head, face and neck	0.000	0.999	0.001
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.001	0.999	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.001	0.999	0.000
H44.3 Other degenerative disorders of globe	0.001	0.999	0.000
S06.3 Focal brain injury	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.999	0.001
M65.0 Abscess of tendon sheath	0.001	0.999	0.000
S06 Intracranial injury	0.001	0.999	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.001	0.999	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.999	0.001
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.000	0.999	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.001	0.999	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.001	0.999	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.999	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.999	0.001
B18.9 Chronic viral hepatitis, unspecified	0.000	0.999	0.001
B18.8 Other chronic viral hepatitis	0.000	0.999	0.001
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.999	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.001	0.999	0.000
M65.28 Calcific tendinitis (Other)	0.001	0.999	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.001	0.999	0.000
M65.26 Calcific tendinitis (Lower leg)	0.001	0.999	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.001	0.999	0.000
M65.24 Calcific tendinitis (Hand)	0.001	0.999	0.000
M65.23 Calcific tendinitis (Forearm)	0.001	0.999	0.000
M65.22 Calcific tendinitis (Upper arm)	0.001	0.999	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.001	0.999	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.999	0.001
S06.9 Intracranial injury, unspecified	0.001	0.999	0.000
Y60.9 During unspecified surgical and medical care	0.001	0.999	0.000
Y60.7 During administration of enema	0.001	0.999	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.001	0.999	0.000
Y60.3 During injection or immunisation	0.001	0.999	0.000
Y60.2 During kidney dialysis or other perfusion	0.001	0.999	0.000
Y60.1 During infusion or transfusion	0.001	0.999	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.999	0.001
S54 Injury of nerves at forearm level	0.001	0.999	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.001	0.999	0.000
D36.7 Other specified sites	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations