TreeWAS – Variant ID: rs1434536

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001	0.000
I20.0 Unstable angina	0.999	0.001	0.000
I25 Chronic ischaemic heart disease	0.997	0.003	0.000
I25.1 Atherosclerotic heart disease	0.996	0.004	0.000
I22 Subsequent myocardial infarction	0.981	0.019	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.955	0.045	0.000
I25.4 Coronary artery aneurysm	0.902	0.098	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.878	0.122	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.869	0.131	0.000
I20.8 Other forms of angina pectoris	0.866	0.134	0.000
I24 Other acute ischaemic heart diseases	0.833	0.167	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.810	0.190	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.791	0.209	0.000
I22.8 Subsequent myocardial infarction of other sites	0.743	0.257	0.000
I20.1 Angina pectoris with documented spasm	0.722	0.278	0.000
I25.6 Silent myocardial ischaemia	0.715	0.285	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.592	0.408	0.000
I25.5 Ischaemic cardiomyopathy	0.590	0.410	0.000
I23 Certain current complications following acute myocardial infarction	0.587	0.413	0.000
I24.1 Dressler's syndrome	0.567	0.432	0.000
I21 Acute myocardial infarction	0.560	0.440	0.000
I21.4 Acute subendocardial myocardial infarction	0.495	0.505	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.477	0.523	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.449	0.551	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.421	0.579	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.421	0.579	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.421	0.579	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.421	0.579	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.421	0.579	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.421	0.579	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.421	0.579	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.401	0.598	0.000
I21.9 Acute myocardial infarction, unspecified	0.401	0.599	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.397	0.603	0.000
I25.3 Aneurysm of heart	0.379	0.621	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.353	0.647	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.306	0.694	0.000
I23.8 Other current complications following acute myocardial infarction	0.291	0.708	0.001
E78.0 Pure hypercholesterolaemia	0.240	0.760	0.000
I25.2 Old myocardial infarction	0.131	0.869	0.000
I24.8 Other forms of acute ischaemic heart disease	0.111	0.889	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.934	0.066
M18 Arthrosis of first carpometacarpal joint	0.000	0.950	0.050
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.951	0.049
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.039	0.961	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.038	0.962	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.964	0.036
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.964	0.036
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.964	0.036
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.966	0.034
E78.9 Disorder of lipoprotein metabolism, unspecified	0.032	0.968	0.000
E78.4 Other hyperlipidaemia	0.032	0.968	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.971	0.029
E78.3 Hyperchylomicronaemia	0.028	0.972	0.000
E78.1 Pure hyperglyceridaemia	0.027	0.973	0.000
E78.2 Mixed hyperlipidaemia	0.027	0.973	0.000
E78.6 Lipoprotein deficiency	0.027	0.973	0.000
N13 Obstructive and reflux uropathy	0.025	0.975	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.024	0.976	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.023	0.977	0.000
N13.8 Other obstructive and reflux uropathy	0.022	0.978	0.000
N13.3 Other and unspecified hydronephrosis	0.022	0.978	0.000
N13.4 Hydroureter	0.022	0.978	0.000
E78.8 Other disorders of lipoprotein metabolism	0.020	0.980	0.000
N13.6 Pyonephrosis	0.020	0.980	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.019	0.981	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.016	0.984	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.016	0.984	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.014	0.985	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.014	0.986	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.988	0.012
L81.4 Other melanin hyperpigmentation	0.000	0.989	0.011
R27.0 Ataxia, unspecified	0.000	0.989	0.011
I86.8 Varicose veins of other specified sites	0.008	0.992	0.000
M20.1 Hallux valgus (acquired)	0.000	0.993	0.007
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.993	0.007
R27 Other lack of coordination	0.000	0.994	0.006
R27.8 Other and unspecified lack of coordination	0.000	0.995	0.005
I35.2 Aortic (valve) stenosis with insufficiency	0.005	0.995	0.000
M22.2 Patellofemoral disorders	0.000	0.995	0.005
S10.9 Superficial injury of neck, part unspecified	0.000	0.995	0.005
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
K25 Gastric ulcer	0.000	0.996	0.004
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
K60.2 Anal fissure, unspecified	0.004	0.996	0.000
I86 Varicose veins of other sites	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.004	0.996	0.000
K25.4 Chronic or unspecified with haemorrhage	0.000	0.996	0.004
S10 Superficial injury of neck	0.000	0.996	0.004
Z88.7 Personal history of allergy to serum and vaccine	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.000	0.996	0.004
I86.4 Gastric varices	0.004	0.996	0.000
S10.1 Other and unspecified superficial injuries of throat	0.000	0.997	0.003
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
L81 Other disorders of pigmentation	0.000	0.997	0.003
K25.0 Acute with haemorrhage	0.000	0.997	0.003
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
C54.1 Endometrium	0.000	0.997	0.003
I86.2 Pelvic varices	0.003	0.997	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S10.8 Superficial injury of other parts of neck	0.000	0.997	0.003
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.997	0.003
K25.2 Acute with both haemorrhage and perforation	0.000	0.997	0.003
K25.1 Acute with perforation	0.000	0.997	0.003
K25.5 Chronic or unspecified with perforation	0.000	0.997	0.003
K25.3 Acute without haemorrhage or perforation	0.000	0.997	0.003
Y83.2 Surgical operation with anastomosis, bypass or graft	0.003	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.003	0.997	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.997	0.000
I86.0 Sublingual varices	0.003	0.997	0.000
L98.0 Pyogenic granuloma	0.000	0.997	0.003
I86.3 Vulval varices	0.003	0.997	0.000
L81.8 Other specified disorders of pigmentation	0.000	0.997	0.003
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.3 Other infection during labour	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
S10.7 Multiple superficial injuries of neck	0.000	0.997	0.003
S10.0 Contusion of throat	0.000	0.997	0.003
K04.6 Periapical abscess with sinus	0.000	0.997	0.003
L05.9 Pilonidal cyst without abscess	0.000	0.997	0.003
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O75.0 Maternal distress during labour and delivery	0.003	0.997	0.000
E80.4 Gilbert's syndrome	0.000	0.997	0.003
L81.2 Freckles	0.000	0.997	0.003
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
L81.7 Pigmented purpuric dermatosis	0.000	0.997	0.003
L81.6 Other disorders of diminished melanin formation	0.000	0.997	0.003
L81.5 Leukoderma, not elsewhere classified	0.000	0.997	0.003
L81.3 Cafe au lait spots	0.000	0.997	0.003
L81.1 Chloasma	0.000	0.997	0.003
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S13.1 Dislocation of cervical vertebra	0.000	0.997	0.003
C54.9 Corpus uteri, unspecified	0.000	0.997	0.003
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.997	0.003
K41 Femoral hernia	0.000	0.997	0.003
O81.4 Vacuum extractor delivery	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
N10-N16 Renal tubulo-interstitial diseases	0.003	0.997	0.000
C54 Malignant neoplasm of corpus uteri	0.000	0.997	0.003
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.000	0.997	0.003
L81.0 Postinflammatory hyperpigmentation	0.000	0.997	0.002
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
S14 Injury of nerves and spinal cord at neck level	0.000	0.997	0.003
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.000	0.997	0.003
S10-S19 Injuries to the neck	0.000	0.997	0.003
S32.50 Fracture of pubis (closed)	0.003	0.997	0.000
S11.9 Open wound of neck, part unspecified	0.000	0.997	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.998	0.002
K09.2 Other cysts of jaw	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
S11 Open wound of neck	0.000	0.998	0.002
M43.62 Torticollis-Cervical	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.002
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.998	0.002
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.998	0.002
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
C54.8 Overlapping lesion of corpus uteri	0.000	0.998	0.002
C54.3 Fundus uteri	0.000	0.998	0.002
C54.2 Myometrium	0.000	0.998	0.002
C54.0 Isthmus uteri	0.000	0.998	0.002
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.998	0.002
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.000	0.998	0.002
S14.5 Injury of cervical sympathetic nerves	0.000	0.998	0.002
S14.4 Injury of peripheral nerves of neck	0.000	0.998	0.002
S14.2 Injury of nerve root of cervical spine	0.000	0.998	0.002
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
H02.8 Other specified disorders of eyelid	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.000	0.998	0.002
S17 Crushing injury of neck	0.000	0.998	0.002
S15 Injury of blood vessels at neck level	0.000	0.998	0.002
S18 Traumatic amputation at neck level	0.000	0.998	0.002
S16 Injury of muscle and tendon at neck level	0.000	0.998	0.002
C21.0 Anus, unspecified	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
I47.2 Ventricular tachycardia	0.002	0.998	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.000	0.998	0.002
S13.5 Sprain and strain of thyroid region	0.000	0.998	0.002
S13.3 Multiple dislocations of neck	0.000	0.998	0.002
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.998	0.002
S13.0 Traumatic rupture of cervical intervertebral disk	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.000	0.998	0.002
S11.1 Open wound involving thyroid gland	0.000	0.998	0.002
S11.0 Open wound involving larynx and trachea	0.000	0.998	0.002
E80.2 Other porphyria	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
S72.40 Fracture of lower end of femur (closed)	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.000	0.998	0.002
S11.8 Open wound of other parts of neck	0.000	0.998	0.002
L05 Pilonidal cyst	0.000	0.998	0.002
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
N80.8 Other endometriosis	0.002	0.998	0.000
S11.7 Multiple open wounds of neck	0.000	0.998	0.002
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
K86 Other diseases of pancreas	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.002	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.002	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.002	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.002	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M20 Acquired deformities of fingers and toes	0.000	0.998	0.002
R09.1 Pleurisy	0.000	0.998	0.002
K09 Cysts of oral region, not elsewhere classified	0.000	0.998	0.002
M50.3 Other cervical disk degeneration	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.000	0.998	0.002
S15.8 Injury of other blood vessels at neck level	0.000	0.998	0.002
S15.7 Injury of multiple blood vessels at neck level	0.000	0.998	0.002
S15.3 Injury of internal jugular vein	0.000	0.998	0.002
S15.2 Injury of external jugular vein	0.000	0.998	0.002
S15.1 Injury of vertebral artery	0.000	0.998	0.002
S15.0 Injury of carotid artery	0.000	0.998	0.002
S17.9 Crushing injury of neck, part unspecified	0.000	0.998	0.002
S17.8 Crushing injury of other parts of neck	0.000	0.998	0.002
S17.0 Crushing injury of larynx and traches	0.000	0.998	0.002
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
F40.0 Agoraphobia	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
R09.3 Abnormal sputum	0.000	0.998	0.002
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.998	0.002
E80.5 Crigler-Najjar syndrome	0.000	0.998	0.002
E80.3 Defects of catalase and peroxydase	0.000	0.998	0.002
E80.0 Hereditary erythropoietic porphyria	0.000	0.998	0.002
R52.9 Pain, unspecified	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
N15 Other renal tubulo-interstitial diseases	0.001	0.998	0.000
O42 Premature rupture of membranes	0.002	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.000	0.998	0.002
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.998	0.002
E80.1 Porphyria cutanea tarda	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.998	0.002
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.998	0.002
S19 Other and unspecified injuries of neck	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
S12 Fracture of neck	0.000	0.998	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.998	0.001
K04.5 Chronic apical periodontitis	0.000	0.998	0.002
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.998	0.000
N15.0 Balkan nephropathy	0.001	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.001
H21 Other disorders of iris and ciliary body	0.001	0.998	0.000
G72.9 Myopathy, unspecified	0.000	0.999	0.001
I38 Endocarditis, valve unspecified	0.001	0.999	0.000
S32.5 Fracture of pubis	0.001	0.999	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.999	0.001
Y91.9 Alcohol involvement, not otherwise specified	0.001	0.999	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.001	0.999	0.000
G70.0 Myasthenia gravis	0.001	0.999	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.001	0.999	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.999	0.001
S19.7 Multiple injuries of neck	0.000	0.999	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.001	0.999	0.000
S12.8 Fracture of other parts of neck	0.000	0.999	0.001
S12.0 Fracture of first cervical vertebra	0.000	0.999	0.001
S00.7 Multiple superficial injuries of head	0.000	0.999	0.001
S51.8 Open wound of other parts of forearm	0.000	0.999	0.001
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.999	0.001
S12.2 Fracture of other specified cervical vertebra	0.000	0.999	0.001
M70.56 Other bursitis of knee-Lower Leg	0.000	0.999	0.001
C51.9 Vulva, unspecified	0.000	0.999	0.001
N15.1 Renal and perinephric abscess	0.001	0.999	0.000
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
L57.4 Cutis laxa senilis	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
X68.9 Unspecified place	0.000	0.999	0.001
S32.51 Fracture of pubis (open)	0.001	0.999	0.000
F40.1 Social phobias	0.001	0.999	0.000
M77.9 Enthesopathy, unspecified	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.999	0.001
M77.96 Enthesopathy, unspecified (Lower leg)	0.001	0.999	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.001	0.999	0.000
S12.01 Fracture of first cervical vertebra (open)	0.000	0.999	0.001
L81.9 Disorder of pigmentation, unspecified	0.000	0.999	0.001
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.001
S19.8 Other specified injuries of neck	0.000	0.999	0.001
S22.3 Fracture of rib	0.000	0.999	0.001
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.999	0.001
S12.81 Fracture of other parts of neck (open)	0.000	0.999	0.001
S12.80 Fracture of other parts of neck (closed)	0.000	0.999	0.001
F45.8 Other somatoform disorders	0.000	0.999	0.001
M43.6 Torticollis	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.999	0.001
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
S12.9 Fracture of neck, part unspecified	0.000	0.999	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.000	0.999	0.001
J03.9 Acute tonsillitis, unspecified	0.000	0.999	0.001
S01.1 Open wound of eyelid and periocular area	0.000	0.999	0.001
F40 Phobic anxiety disorders	0.001	0.999	0.000
O81 Single delivery by forceps and vacuum extractor	0.001	0.999	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.999	0.001
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.999	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.001	0.999	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.999	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.999	0.001
H11.3 Conjunctival haemorrhage	0.000	0.999	0.001
H21.4 Pupillary membranes	0.001	0.999	0.000
I51.0 Cardiac septal defect, acquired	0.000	0.999	0.001
K82.9 Disease of gallbladder, unspecified	0.001	0.999	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.001	0.999	0.000
S22.31 Fracture of rib (open)	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.000	0.999	0.001
R90.0 Intracranial space-occupying lesion	0.000	0.999	0.001
M22 Disorders of patella	0.000	0.999	0.001
M43.69 Torticollis-Site unspe	0.000	0.999	0.001
M43.68 Torticollis-Sacral/sacrococ	0.000	0.999	0.001
M43.67 Torticollis-Lumbosacral	0.000	0.999	0.001
M43.66 Torticollis-Lumbar	0.000	0.999	0.001
M43.65 Torticollis-Thoracolumbar	0.000	0.999	0.001
M43.64 Torticollis-Thoracic	0.000	0.999	0.001
M43.63 Torticollis-Cervicothoracic	0.000	0.999	0.001
M43.61 Torticollis-Occipit-atl-axl	0.000	0.999	0.001
M43.60 Torticollis-Mult site	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
E14.9 Without complications	0.000	0.999	0.001
F41.2 Mixed anxiety and depressive disorder	0.000	0.999	0.001
G46.7 Other lacunar syndromes	0.001	0.999	0.000
H18.4 Corneal degeneration	0.001	0.999	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.999	0.000
H21.2 Degeneration of iris and ciliary body	0.001	0.999	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.001	0.999	0.000
M22.9 Disorder of patella, unspecified	0.000	0.999	0.001
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.999	0.001
C51 Malignant neoplasm of vulva	0.000	0.999	0.001
S12.91 Fracture of neck, part unspecified (open)	0.000	0.999	0.001
H18.3 Changes in corneal membranes	0.001	0.999	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.999	0.001
S29.9 Unspecified injury of thorax	0.001	0.999	0.000
C67.4 Posterior wall of bladder	0.000	0.999	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.999	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.999	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.999	0.000
S62.6 Fracture of other finger	0.000	0.999	0.001
H69 Other disorders of Eustachian tube	0.000	0.999	0.001
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.001	0.999	0.000
M02.96 Reactive arthropathy, unspecified (Lower leg)	0.001	0.999	0.000
A60.0 Herpesviral infection of genitalia and urogenital tract	0.000	0.999	0.001
F40.9 Phobic anxiety disorder, unspecified	0.001	0.999	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.999	0.001
M22.1 Recurrent subluxation of patella	0.000	0.999	0.001
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.000	0.999	0.001
C51.8 Overlapping lesion of vulva	0.000	0.999	0.001
C51.2 Clitoris	0.000	0.999	0.001
C51.1 Labium minus	0.000	0.999	0.001
D13.4 Liver	0.000	0.999	0.001
F45.9 Somatoform disorder, unspecified	0.000	0.999	0.001
I30.1 Infective pericarditis	0.000	0.999	0.001
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.001	0.999	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.001	0.999	0.000
C51.0 Labium majus	0.000	0.999	0.001
N28.8 Other specified disorders of kidney and ureter	0.001	0.999	0.000
O64.1 Obstructed labour due to breech presentation	0.000	0.999	0.001
S19.9 Unspecified injury of neck	0.000	0.999	0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
F40.8 Other phobic anxiety disorders	0.001	0.999	0.000
H69.0 Patulous Eustachian tube	0.000	0.999	0.001
I47.9 Paroxysmal tachycardia, unspecified	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.999	0.001
Z12.3 Special screening examination for neoplasm of breast	0.000	0.999	0.001
Z34.8 Supervision of other normal pregnancy	0.001	0.999	0.000
H18 Other disorders of cornea	0.001	0.999	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.999	0.001
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.999	0.001
M89.55 Osteolysis (Pelvic region and thigh)	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.999	0.000
H18.1 Bullous keratopathy	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
H21.0 Hyphaema	0.001	0.999	0.000
Q14.1 Congenital malformation of retina	0.000	0.999	0.001
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
Z63.4 Disappearance and death of family member	0.001	0.999	0.000
M15-M19 Arthrosis	0.000	0.999	0.001
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.999	0.001
E24.0 Pituitary-dependent Cushing's disease	0.000	0.999	0.001
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
M22.3 Other derangements of patella	0.000	0.999	0.001
S51.7 Multiple open wounds of forearm	0.000	0.999	0.001
M77.94 Enthesopathy, unspecified (Hand)	0.001	0.999	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.999	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
C44.1 Skin of eyelid, including canthus	0.000	0.999	0.001
O81.0 Low forceps delivery	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.000	0.999	0.001
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
C77.0 Lymph nodes of head, face and neck	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.000	0.999	0.001
Q18.8 Other specified congenital malformations of face and neck	0.000	0.999	0.001
Q18.7 Microcheilia	0.000	0.999	0.001
Q18.6 Macrocheilia	0.000	0.999	0.001
Q18.5 Microstomia	0.000	0.999	0.001
Q18.4 Macrostomia	0.000	0.999	0.001
Q18.3 Webbing of neck	0.000	0.999	0.001
Q18.2 Other branchial cleft malformations	0.000	0.999	0.001
M82 Osteoporosis in diseases classified elsewhere	0.001	0.999	0.000
A39.4 Meningococcaemia, unspecified	0.001	0.999	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.999	0.000
M15.8 Other polyarthrosis	0.000	0.999	0.001
M19.1 Posttraumatic arthrosis of other joints	0.001	0.999	0.000
M22.8 Other disorders of patella	0.000	0.999	0.001
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.999	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.999	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.999	0.000
C71 Malignant neoplasm of brain	0.000	0.999	0.001
G20 Parkinson's disease	0.000	0.999	0.001
C51-C58 Malignant neoplasms of female genital organs	0.000	0.999	0.001
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.001	0.999	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.001	0.999	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.001	0.999	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.001	0.999	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.001	0.999	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations