TreeWAS – Variant ID: rs1454694

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.111	0.889	0.000
O16 Unspecified maternal hypertension	0.108	0.892	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.105	0.895	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.085	0.915	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.077	0.923	0.000
O15 Eclampsia	0.076	0.924	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.070	0.930	0.000
O12.0 Gestational oedema	0.067	0.933	0.000
O12.1 Gestational proteinuria	0.066	0.934	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.065	0.935	0.000
O12.2 Gestational oedema with proteinuria	0.061	0.939	0.000
O15.9 Eclampsia, unspecified as to time period	0.054	0.945	0.000
O15.2 Eclampsia in the puerperium	0.054	0.945	0.000
O15.1 Eclampsia in labour	0.054	0.945	0.000
O15.0 Eclampsia in pregnancy	0.054	0.945	0.000
E10.9 Without complications	0.051	0.949	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.050	0.949	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.050	0.949	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.050	0.949	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.050	0.949	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.050	0.949	0.000
O14.0 Moderate preeclampsia	0.049	0.951	0.000
E10 Insulin-dependent diabetes mellitus	0.049	0.951	0.000
O14.2 HELLP syndrome	0.046	0.953	0.000
E10.4 With neurological complications	0.046	0.954	0.000
E10.8 With unspecified complications	0.045	0.955	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.045	0.955	0.000
O14.1 Severe preeclampsia	0.043	0.957	0.000
E10.2 With renal complications	0.041	0.959	0.000
E10.1 With ketoacidosis	0.038	0.962	0.000
E10.7 With multiple complications	0.037	0.963	0.000
O14.9 Preeclampsia, unspecified	0.036	0.964	0.000
E10.6 With other specified complications	0.035	0.965	0.000
E10.5 With peripheral circulatory complications	0.033	0.967	0.000
E10.0 With coma	0.032	0.968	0.000
E10.3 With ophthalmic complications	0.031	0.969	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.981	0.019
S92.0 Fracture of calcaneus	0.000	0.984	0.016
S92 Fracture of foot, except ankle	0.000	0.986	0.014
S92.3 Fracture of metatarsal bone	0.000	0.987	0.013
K07.6 Temporomandibular joint disorders	0.013	0.987	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.987	0.013
G30.9 Alzheimer's disease, unspecified	0.012	0.988	0.000
S92.1 Fracture of talus	0.000	0.988	0.012
S92.01 Fracture of calcaneus (open)	0.000	0.988	0.012
S92.7 Multiple fractures of foot	0.000	0.989	0.011
S92.2 Fracture of other tarsal bone(s)	0.000	0.989	0.011
G30 Alzheimer's disease	0.011	0.989	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.011	0.989	0.000
G31.2 Degeneration of nervous system due to alcohol	0.011	0.989	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.011	0.989	0.000
S92.10 Fracture of talus (closed)	0.000	0.989	0.010
K07 Dentofacial anomalies [including malocclusion]	0.010	0.990	0.000
S92.9 Fracture of foot, unspecified	0.000	0.990	0.010
S92.5 Fracture of other toe	0.000	0.990	0.010
S92.31 Fracture of metatarsal bone (open)	0.000	0.990	0.010
G30-G32 Other degenerative diseases of the nervous system	0.010	0.990	0.000
K07.4 Malocclusion, unspecified	0.009	0.990	0.000
E10-E14 Diabetes mellitus	0.009	0.991	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.991	0.009
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.991	0.009
G30.1 Alzheimer's disease with late onset	0.009	0.991	0.000
S92.11 Fracture of talus (open)	0.000	0.991	0.009
K07.1 Anomalies of jaw-cranial base relationship	0.009	0.991	0.000
G30.0 Alzheimer's disease with early onset	0.009	0.991	0.000
K07.2 Anomalies of dental arch relationship	0.009	0.991	0.000
K60.3 Anal fistula	0.000	0.991	0.009
K07.0 Major anomalies of jaw size	0.008	0.992	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.008	0.992	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.992	0.008
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.992	0.008
S92.4 Fracture of great toe	0.000	0.992	0.008
S92.51 Fracture of other toe (open)	0.000	0.992	0.008
G31.1 Senile degeneration of brain, not elsewhere classified	0.008	0.992	0.000
G31.0 Circumscribed brain atrophy	0.008	0.992	0.000
K07.8 Other dentofacial anomalies	0.008	0.992	0.000
K07.5 Dentofacial functional abnormalities	0.008	0.992	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.992	0.007
S92.90 Fracture of foot, unspecified (closed)	0.000	0.992	0.007
G30.8 Other Alzheimer's disease	0.007	0.992	0.000
K07.3 Anomalies of tooth position	0.007	0.992	0.000
G31.8 Other specified degenerative diseases of nervous system	0.007	0.993	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.007	0.993	0.000
E13 Other specified diabetes mellitus	0.007	0.993	0.000
E12 Malnutrition-related diabetes mellitus	0.007	0.993	0.000
K07.9 Dentofacial anomaly, unspecified	0.007	0.993	0.000
S92.50 Fracture of other toe (closed)	0.000	0.993	0.007
E14 Unspecified diabetes mellitus	0.006	0.993	0.000
S92.40 Fracture of great toe (closed)	0.000	0.994	0.005
E14.5 With peripheral circulatory complications	0.006	0.994	0.000
I49.5 Sick sinus syndrome	0.000	0.994	0.006
E14.1 With ketoacidosis	0.006	0.994	0.000
E13.9 Without complications	0.005	0.995	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.005	0.995	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.005	0.995	0.000
E14.9 Without complications	0.005	0.995	0.000
E13.8 With unspecified complications	0.005	0.995	0.000
E13.7 With multiple complications	0.005	0.995	0.000
E13.6 With other specified complications	0.005	0.995	0.000
E13.5 With peripheral circulatory complications	0.005	0.995	0.000
E13.4 With neurological complications	0.005	0.995	0.000
E13.3 With ophthalmic complications	0.005	0.995	0.000
E13.2 With renal complications	0.005	0.995	0.000
E13.1 With ketoacidosis	0.005	0.995	0.000
E13.0 With coma	0.005	0.995	0.000
S72.40 Fracture of lower end of femur (closed)	0.005	0.995	0.000
E12.9 Without complications	0.005	0.995	0.000
E12.8 With unspecified complications	0.005	0.995	0.000
E12.7 With multiple complications	0.005	0.995	0.000
E12.6 With other specified complications	0.005	0.995	0.000
E12.5 With peripheral circulatory complications	0.005	0.995	0.000
E12.4 With neurological complications	0.005	0.995	0.000
E12.3 With ophthalmic complications	0.005	0.995	0.000
E12.2 With renal complications	0.005	0.995	0.000
E12.1 With ketoacidosis	0.005	0.995	0.000
E12.0 With coma	0.005	0.995	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.995	0.005
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.995	0.005
E14.7 With multiple complications	0.005	0.995	0.000
E14.2 Withrenal complications	0.005	0.995	0.000
E14.0 With coma	0.005	0.995	0.000
E14.4 With neurological complications	0.005	0.995	0.000
E14.6 With other specified complications	0.005	0.995	0.000
S92.41 Fracture of great toe (open)	0.000	0.995	0.004
S42.30 Fracture of shaft of humerus (closed)	0.005	0.995	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.005	0.995	0.000
R04.2 Haemoptysis	0.005	0.995	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.005	0.995	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.005	0.995	0.000
B37.9 Candidiasis, unspecified	0.004	0.996	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.004	0.996	0.000
B37.0 Candidal stomatitis	0.004	0.996	0.000
Z87.0 Personal history of diseases of the respiratory system	0.004	0.996	0.000
S72.4 Fracture of lower end of femur	0.004	0.996	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.004	0.996	0.000
E14.8 With unspecified complications	0.004	0.996	0.000
M06.0 Seronegative rheumatoid arthritis	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.996	0.004
M00.9 Pyogenic arthritis, unspecified	0.004	0.996	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.004	0.996	0.000
B37.2 Candidiasis of skin and nail	0.004	0.996	0.000
B37 Candidiasis	0.004	0.996	0.000
S72.41 Fracture of lower end of femur (open)	0.004	0.996	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.996	0.004
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.000	0.997	0.003
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.003	0.997	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.997	0.003
B37.7 Candidal septicaemia	0.003	0.997	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.003
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.003	0.997	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.003	0.997	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.997	0.003
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.003
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
H11 Other disorders of conjunctiva	0.000	0.997	0.003
B37.6 Candidal endocarditis	0.003	0.997	0.000
B37.5 Candidal meningitis	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.997	0.003
H81.0 Meniere's disease	0.000	0.997	0.003
K81.0 Acute cholecystitis	0.003	0.997	0.000
K72 Hepatic failure, not elsewhere classified	0.003	0.997	0.000
O32.1 Maternal care for breech presentation	0.003	0.997	0.000
S90.0 Contusion of ankle	0.000	0.997	0.003
B20-B24 Human immunodeficiency virus [HIV] disease	0.003	0.997	0.000
N32.9 Bladder disorder, unspecified	0.000	0.997	0.003
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.997	0.003
S90.2 Contusion of toe(s) with damage to nail	0.000	0.997	0.003
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.997	0.003
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
R52.1 Chronic intractable pain	0.000	0.997	0.003
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
B37.4 Candidiasis of other urogenital sites	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.997	0.003
M00 Pyogenic arthritis	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.000	0.997	0.003
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.997	0.003
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
M10.96 Gout, unspecified (Lower leg)	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.003	0.997	0.000
S72 Fracture of femur	0.003	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.997	0.000
K72.1 Chronic hepatic failure	0.002	0.997	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.997	0.002
S90.1 Contusion of toe(s) without damage to nail	0.000	0.997	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.997	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.997	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.997	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.997	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.997	0.002
S94.1 Injury of medial plantar nerve	0.000	0.997	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.997	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.997	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.997	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.997	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.997	0.002
S95.1 Injury of plantar artery of foot	0.000	0.997	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.997	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.997	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.997	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.997	0.002
S98.1 Traumatic amputation of one toe	0.000	0.997	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.997	0.002
M06.34 Rheumatoid nodule (Hand)	0.002	0.997	0.000
R23.4 Changes in skin texture	0.003	0.997	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.997	0.000
Q54.9 Hypospadias, unspecified	0.002	0.997	0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.002	0.997	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.997	0.000
E61.1 Iron deficiency	0.002	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.997	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.998	0.002
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
S99.7 Multiple injuries of ankle and foot	0.000	0.998	0.002
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.000	0.998	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
W07.0 Home	0.000	0.998	0.002
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
B37.1 Pulmonary candidiasis	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.002	0.998	0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.002	0.998	0.000
B20.6 HIV disease resulting in Pneumocystis carinii pneumonia	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
H11.2 Conjunctival scars	0.000	0.998	0.002
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
B23.8 HIV disease resulting in other specified conditions	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
H11.1 Conjunctival degenerations and deposits	0.000	0.998	0.002
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
K02.8 Other dental caries	0.000	0.998	0.002
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.002	0.998	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.002	0.998	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.002	0.998	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.002	0.998	0.000
K02.9 Dental caries, unspecified	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
B37.3 Candidiasis of vulva and vagina	0.002	0.998	0.000
S72.7 Multiple fractures of femur	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
G82.1 Spastic paraplegia	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.998	0.000
B20.9 HIV disease resulting in unspecified infectious or parasitic disease	0.002	0.998	0.000
B20.8 HIV disease resulting in other infectious and parasitic diseases	0.002	0.998	0.000
B20.7 HIV disease resulting in multiple infections	0.002	0.998	0.000
B20.5 HIV disease resulting in other mycoses	0.002	0.998	0.000
B20.4 HIV disease resulting in candidiasis	0.002	0.998	0.000
B20.3 HIV disease resulting in other viral infections	0.002	0.998	0.000
B20.2 HIV disease resulting in cytomegaloviral disease	0.002	0.998	0.000
B20.1 HIV disease resulting in other bacterial infections	0.002	0.998	0.000
B20.0 HIV disease resulting in mycobacterial infection	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.998	0.000
V48.4 Person injured while boarding or alighting	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
B23.2 HIV disease resulting in haematological and immunological abnormalities, not elsewhere classified	0.002	0.998	0.000
B23.1 HIV disease resulting in (persistent) generalised lymphadenopathy	0.002	0.998	0.000
B23.0 Acute HIV infection syndrome	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
K73 Chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
H11.0 Pterygium	0.000	0.998	0.002
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.002
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.002
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
V48 Car occupant injured in noncollision transport accident	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
S10.9 Superficial injury of neck, part unspecified	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.998	0.002
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
T86.0 Bone-marrow transplant rejection	0.002	0.998	0.000
W50.9 Unspecified place	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.002	0.998	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations