TreeWAS – Variant ID: rs1456893

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.9 Crohn's disease, unspecified	0.998	0.002	0.000
K50 Crohn's disease [regional enteritis]	0.998	0.002	0.000
K50.0 Crohn's disease of small intestine	0.984	0.016	0.000
K50.8 Other Crohn's disease	0.972	0.028	0.000
K50.1 Crohn's disease of large intestine	0.967	0.033	0.000
K50-K52 Noninfective enteritis and colitis	0.556	0.444	0.000
K52 Other non-infective gastro-enteritis and colitis	0.455	0.545	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.421	0.579	0.000
K51 Ulcerative colitis	0.415	0.585	0.000
K52.3 Indeterminate colitis	0.388	0.612	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.377	0.623	0.000
K51.4 Pseudopolyposis of colon	0.362	0.638	0.000
K51.2 Ulcerative (chronic) proctitis	0.327	0.673	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.320	0.679	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.297	0.703	0.000
K51.5 Mucosal proctocolitis	0.285	0.715	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.280	0.720	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.257	0.743	0.000
K52.1 Toxic gastro-enteritis and colitis	0.257	0.743	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.253	0.747	0.000
K51.9 Ulcerative colitis, unspecified	0.129	0.871	0.000
S01.1 Open wound of eyelid and periocular area	0.122	0.878	0.000
K51.8 Other ulcerative colitis	0.121	0.879	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.081	0.918	0.000
D51 Vitamin B12 deficiency anaemia	0.079	0.921	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.075	0.925	0.000
D50.9 Iron deficiency anaemia, unspecified	0.069	0.931	0.000
D50-D53 Nutritional anaemias	0.067	0.933	0.000
D50 Iron deficiency anaemia	0.067	0.933	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.062	0.937	0.000
D51.2 Transcobalamin II deficiency	0.057	0.943	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.057	0.943	0.000
D50.8 Other iron deficiency anaemias	0.055	0.945	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.049	0.950	0.000
Y83.8 Other surgical procedures	0.047	0.953	0.000
D50.1 Sideropenic dysphagia	0.045	0.955	0.000
D52 Folate deficiency anaemia	0.044	0.956	0.000
D53 Other nutritional anaemias	0.039	0.961	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.034	0.966	0.000
D52.8 Other folate deficiency anaemias	0.031	0.968	0.000
D52.1 Drug-induced folate deficiency anaemia	0.031	0.968	0.000
D52.0 Dietary folate deficiency anaemia	0.031	0.968	0.000
D53.8 Other specified nutritional anaemias	0.028	0.972	0.000
D53.2 Scorbutic anaemia	0.028	0.972	0.000
D53.0 Protein deficiency anaemia	0.028	0.972	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.028	0.972	0.000
D52.9 Folate deficiency anaemia, unspecified	0.027	0.973	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.023	0.977	0.000
S29.9 Unspecified injury of thorax	0.021	0.979	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.020	0.980	0.000
D53.9 Nutritional anaemia, unspecified	0.019	0.980	0.000
S22.1 Multiple fractures of thoracic spine	0.019	0.981	0.000
S29 Other and unspecified injuries of thorax	0.019	0.981	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.019	0.981	0.000
H40.0 Glaucoma suspect	0.018	0.982	0.000
H40 Glaucoma	0.018	0.982	0.000
H40.1 Primary open-angle glaucoma	0.018	0.982	0.000
S22.4 Multiple fractures of ribs	0.017	0.983	0.000
S20-S29 Injuries to the thorax	0.017	0.983	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.017	0.983	0.000
R25.2 Cramp and spasm	0.017	0.983	0.000
M45 Ankylosing spondylitis	0.017	0.983	0.000
S22.40 Multiple fractures of ribs (closed)	0.016	0.984	0.000
S27 Injury of other and unspecified intrathoracic organs	0.016	0.984	0.000
D80-D89 Certain disorders involving the immune mechanism	0.016	0.984	0.000
H40.5 Glaucoma secondary to other eye disorders	0.016	0.984	0.000
S22.2 Fracture of sternum	0.016	0.984	0.000
H21.8 Other specified disorders of iris and ciliary body	0.016	0.984	0.000
D86 Sarcoidosis	0.016	0.984	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.015	0.985	0.000
D86.8 Sarcoidosis of other and combined sites	0.015	0.985	0.000
D55-D59 Haemolytic anaemias	0.015	0.985	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.014	0.986	0.000
S22.5 Flail chest	0.014	0.986	0.000
S22.20 Fracture of sternum (closed)	0.014	0.986	0.000
H40.8 Other glaucoma	0.014	0.986	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.014	0.986	0.000
S29.0 Injury of muscle and tendon at thorax level	0.014	0.986	0.000
H40.9 Glaucoma, unspecified	0.014	0.986	0.000
H21 Other disorders of iris and ciliary body	0.014	0.986	0.000
D86.3 Sarcoidosis of skin	0.014	0.986	0.000
S29.7 Multiple injuries of thorax	0.013	0.986	0.000
S22.9 Fracture of bony thorax, part unspecified	0.013	0.986	0.000
S22.8 Fracture of other parts of bony thorax	0.013	0.986	0.000
S27.2 Traumatic heamopneumothorax	0.014	0.986	0.000
D86.9 Sarcoidosis, unspecified	0.014	0.986	0.000
S29.8 Other specified injuries of thorax	0.013	0.987	0.000
S27.0 Traumatic pneumothorax	0.013	0.987	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.013	0.987	0.000
S27.3 Other injuries of lung	0.013	0.987	0.000
H40.6 Glaucoma secondary to drugs	0.013	0.987	0.000
S26 Injury of heart	0.013	0.987	0.000
D59 Acquired haemolytic anaemia	0.013	0.987	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.013	0.987	0.000
S24 Injury of nerves and spinal cord at thorax level	0.013	0.987	0.000
S22.41 Multiple fractures of ribs (open)	0.012	0.987	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.012	0.988	0.000
S25 Injury of blood vessels of thorax	0.012	0.988	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.012	0.988	0.000
H21.4 Pupillary membranes	0.012	0.988	0.000
H40.4 Glaucoma secondary to eye inflammation	0.012	0.988	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.012	0.988	0.000
H40.3 Glaucoma secondary to eye trauma	0.012	0.988	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.012	0.988	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.012	0.988	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.012	0.988	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.012	0.988	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.012	0.988	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.012	0.988	0.000
D80 Immunodeficiency with predominantly antibody defects	0.012	0.988	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.1 Traumatic haemothorax	0.012	0.988	0.000
H40.2 Primary angle-closure glaucoma	0.012	0.988	0.000
S27.8 Injury of other specified intrathoracic organs	0.012	0.988	0.000
S22.3 Fracture of rib	0.012	0.988	0.000
S27.9 Injury of unspecified intrathoracic organ	0.012	0.988	0.000
S27.7 Multiple injuries of intrathoracic organs	0.012	0.988	0.000
S27.6 Injury of pleura	0.012	0.988	0.000
S27.5 Injury of thoracic trachea	0.012	0.988	0.000
S27.4 Injury of bronchus	0.012	0.988	0.000
D81 Combined immunodeficiencies	0.012	0.988	0.000
S22.21 Fracture of sternum (open)	0.012	0.988	0.000
D59.1 Other autoimmune haemolytic anaemias	0.012	0.988	0.000
D82 Immunodeficiency associated with other major defects	0.011	0.988	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.012	0.988	0.000
D58 Other hereditary haemolytic anaemias	0.011	0.988	0.000
D83 Common variable immunodeficiency	0.011	0.989	0.000
D57 Sickle-cell disorders	0.011	0.989	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.011	0.989	0.000
J92.0 Pleural plaque with presence of asbestos	0.011	0.989	0.000
J38.7 Other diseases of larynx	0.000	0.989	0.011
D89.1 Cryoglobulinaemia	0.011	0.989	0.000
S22.50 Flail chest (closed)	0.011	0.989	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.011	0.989	0.000
D55 Anaemia due to enzyme disorders	0.011	0.989	0.000
R25.1 Tremor, unspecified	0.010	0.990	0.000
S22.51 Flail chest (open)	0.010	0.990	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.010	0.990	0.000
R25 Abnormal involuntary movements	0.010	0.990	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.010	0.990	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.010	0.990	0.000
S01 Open wound of head	0.010	0.990	0.000
H21.2 Degeneration of iris and ciliary body	0.010	0.990	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.010	0.990	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.010	0.990	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.010	0.990	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.010	0.990	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.010	0.990	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.010	0.990	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.010	0.990	0.000
S26.8 Other injuries of heart	0.010	0.990	0.000
D89.3 Immune reconstitution syndrome	0.010	0.990	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.010	0.990	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.010	0.990	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.010	0.990	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.010	0.990	0.000
D84 Other immunodeficiencies	0.010	0.990	0.000
H21.0 Hyphaema	0.010	0.990	0.000
S26.9 Injury of heart, unspecified	0.009	0.990	0.000
S26.0 Injury of heart with haemopericardium	0.009	0.990	0.000
D59.8 Other acquired haemolytic anaemias	0.009	0.991	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.009	0.991	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.009	0.991	0.000
D59.3 Haemolytic-uraemic syndrome	0.009	0.991	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.009	0.991	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.009	0.991	0.000
D56 Thalassaemia	0.009	0.991	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.009	0.991	0.000
S24.6 Injury of unspecified nerve of thorax	0.009	0.991	0.000
S24.5 Injury of other nerves of thorax	0.009	0.991	0.000
S24.4 Injury of thoracic sympathetic nerves	0.009	0.991	0.000
S24.3 Injury of peripheral nerves of thorax	0.009	0.991	0.000
S24.2 Injury of nerve root of thoracic spine	0.009	0.991	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.009	0.991	0.000
J92.9 Pleural plaque without asbestos	0.009	0.991	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.009	0.991	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.009	0.991	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.009	0.991	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.009	0.991	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.009	0.991	0.000
S22.0 Fracture of thoracic vertebra	0.009	0.991	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.009	0.991	0.000
S25.8 Injury of other blood vessels of thorax	0.009	0.991	0.000
S25.7 Injury of multiple blood vessels of thorax	0.009	0.991	0.000
S25.5 Injury of intercostal blood vessels	0.009	0.991	0.000
S25.4 Injury of pulmonary blood vessels	0.009	0.991	0.000
S25.3 Injury of innominate or subclavian vein	0.009	0.991	0.000
S25.2 Injury of superior vena cava	0.009	0.991	0.000
S25.1 Injury of innominate or subclavian artery	0.009	0.991	0.000
S25.0 Injury of thoracic aorta	0.009	0.991	0.000
S28.1 Traumatic amputation of part of thorax	0.009	0.991	0.000
S28.0 Crushed chest	0.009	0.991	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.009	0.991	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.009	0.991	0.000
S01.2 Open wound of nose	0.009	0.991	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.009	0.991	0.000
H40-H42 Glaucoma	0.009	0.991	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.009	0.991	0.000
S23.3 Sprain and strain of thoracic spine	0.009	0.991	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.009	0.991	0.000
S23.1 Dislocation of thoracic vertebra	0.009	0.991	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.009	0.991	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.009	0.991	0.000
S21 Open wound of thorax	0.009	0.991	0.000
H20 Iridocyclitis	0.009	0.991	0.000
J92 Pleural plaque	0.009	0.991	0.000
D57.1 Sickle-cell anaemia without crisis	0.009	0.991	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.009	0.991	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.009	0.991	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.009	0.991	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.009	0.991	0.000
S23.4 Sprain and strain of ribs and sternum	0.009	0.991	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.009	0.991	0.000
D58.2 Other haemoglobinopathies	0.009	0.991	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.009	0.991	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.008	0.991	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.009	0.991	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.008	0.991	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.008	0.991	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.008	0.991	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.008	0.991	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.008	0.991	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.008	0.991	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.008	0.991	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.008	0.991	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.008	0.991	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.008	0.991	0.000
D81.9 Combined immunodeficiency, unspecified	0.008	0.991	0.000
D81.8 Other combined immunodeficiencies	0.008	0.991	0.000
D81.7 Major histocompatibility complex class II deficiency	0.008	0.991	0.000
D81.6 Major histocompatibility complex class I deficiency	0.008	0.991	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.008	0.991	0.000
D81.4 Nezelof's syndrome	0.008	0.991	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.008	0.991	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.008	0.991	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.008	0.991	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.008	0.991	0.000
S22.31 Fracture of rib (open)	0.009	0.991	0.000
S01.4 Open wound of cheek and temporomandibular area	0.009	0.991	0.000
D86.1 Sarcoidosis of lymph nodes	0.008	0.991	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.008	0.991	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.008	0.991	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.008	0.991	0.000
D82.2 Immunodeficiency with short-limbed stature	0.008	0.991	0.000
D82.0 Wiskott-Aldrich syndrome	0.008	0.991	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.008	0.991	0.000
D58.1 Hereditary elliptocytosis	0.008	0.991	0.000
H20.0 Acute and subacute iridocyclitis	0.008	0.992	0.000
D83.8 Other common variable immunodeficiencies	0.008	0.992	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.008	0.992	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.008	0.992	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.008	0.992	0.000
D57.8 Other sickle-cell disorders	0.008	0.992	0.000
D57.3 Sickle-cell trait	0.008	0.992	0.000
D57.2 Double heterozygous sickling disorders	0.008	0.992	0.000
D57.0 Sickle-cell anaemia with crisis	0.008	0.992	0.000
D58.0 Hereditary spherocytosis	0.008	0.992	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.008	0.992	0.000
D83.9 Common variable immunodeficiency, unspecified	0.008	0.992	0.000
S02.60 Fracture of mandible (closed)	0.008	0.992	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.008	0.992	0.000
D55.8 Other anaemias due to enzyme disorders	0.008	0.992	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.008	0.992	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.008	0.992	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.008	0.992	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.008	0.992	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.008	0.992	0.000
S20 Superficial injury of thorax	0.008	0.992	0.000
D75.1 Secondary polycythaemia	0.008	0.992	0.000
D82.1 Di George's syndrome	0.007	0.992	0.000
R25.0 Abnormal head movements	0.007	0.992	0.000
D75 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
S00.9 Superficial injury of head, part unspecified	0.008	0.992	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.007	0.993	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.007	0.993	0.000
D84.8 Other specified immunodeficiencies	0.007	0.993	0.000
H20.8 Other iridocyclitis	0.007	0.993	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.007	0.993	0.000
S02.6 Fracture of mandible	0.007	0.993	0.000
S21.0 Open wound of breast	0.007	0.993	0.000
H20.1 Chronic iridocyclitis	0.007	0.993	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.007	0.993	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.007	0.993	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.007	0.993	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.007	0.993	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.007	0.993	0.000
D56.9 Thalassaemia, unspecified	0.007	0.993	0.000
D56.8 Other thalassaemias	0.007	0.993	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.007	0.993	0.000
D56.2 Delta-beta thalassaemia	0.007	0.993	0.000
D56.0 Alpha thalassaemia	0.007	0.993	0.000
R25.3 Fasciculation	0.007	0.993	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.007	0.993	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.007	0.993	0.000
S01.7 Multiple open wounds of head	0.007	0.993	0.000
H20.9 Iridocyclitis, unspecified	0.007	0.993	0.000
S22.01 Fracture of thoracic vertebra (open)	0.007	0.993	0.000
D56.3 Thalassaemia trait	0.007	0.993	0.000
H17 Corneal scars and opacities	0.007	0.993	0.000
H15 Disorders of sclera	0.007	0.993	0.000
D60-D64 Aplastic and other anaemias	0.007	0.993	0.000
H42 Glaucoma in diseases classified elsewhere	0.007	0.993	0.000
E07.9 Disorder of thyroid, unspecified	0.007	0.993	0.000
S21.8 Open wound of other parts of thorax	0.006	0.993	0.000
S21.7 Multiple open wounds of thoracic wall	0.006	0.993	0.000
H20.2 Lens-induced iridocyclitis	0.007	0.993	0.000
S00-S09 Injuries to the head	0.007	0.993	0.000
S22.30 Fracture of rib (closed)	0.007	0.993	0.000
S02 Fracture of skull and facial bones	0.007	0.993	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.993	0.007
D84.1 Defects in the complement system	0.006	0.993	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.006	0.994	0.000
X62.9 Unspecified place	0.006	0.994	0.000
S00 Superficial injury of head	0.006	0.994	0.000
S02.0 Fracture of vault of skull	0.006	0.994	0.000
S20.0 Contusion of breast	0.006	0.994	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.006	0.994	0.000
E85.9 Amyloidosis, unspecified	0.000	0.994	0.006
S02.00 Fracture of vault of skull (closed)	0.006	0.994	0.000
S00.7 Multiple superficial injuries of head	0.006	0.994	0.000
S21.1 Open wound of front wall of thorax	0.006	0.994	0.000
D84.9 Immunodeficiency, unspecified	0.006	0.994	0.000
S21.2 Open wound of back wall of thorax	0.006	0.994	0.000
D56.1 Beta thalassaemia	0.006	0.994	0.000
S00.1 Contusion of eyelid and periocular area	0.006	0.994	0.000
S20.7 Multiple superficial injuries of thorax	0.006	0.994	0.000
S20.1 Other and unspecified superficial injuries of breast	0.006	0.994	0.000
S01.9 Open wound of head, part unspecified	0.006	0.994	0.000
D75.0 Familial erythrocytosis	0.006	0.994	0.000
S02.5 Fracture of tooth	0.006	0.994	0.000
D86.0 Sarcoidosis of lung	0.006	0.994	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.005	0.994	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.005	0.994	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.005	0.994	0.000
D75.2 Essential thrombocytosis	0.006	0.994	0.000
H15.1 Episcleritis	0.005	0.994	0.000
S20.2 Contusion of thorax	0.006	0.994	0.000
K56.2 Volvulus	0.006	0.994	0.000
H15.9 Disorder of sclera, unspecified	0.005	0.994	0.000
E85.4 Organ-limited amyloidosis	0.000	0.994	0.005
S02.61 Fracture of mandible (open)	0.005	0.995	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
S08 Traumatic amputation of part of head	0.005	0.995	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.005	0.995	0.000
S20.4 Other superficial injuries of back wall of thorax	0.005	0.995	0.000
D74 Methaemoglobinaemia	0.005	0.995	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.005	0.995	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.005	0.995	0.000
E85 Amyloidosis	0.000	0.995	0.005
S03 Dislocation, sprain and strain of joints and ligaments of head	0.005	0.995	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.005	0.995	0.000
H17.9 Corneal scar and opacity, unspecified	0.005	0.995	0.000
H17.1 Other central corneal opacity	0.005	0.995	0.000
H17.0 Adherent leukoma	0.005	0.995	0.000
S02.7 Multiple fractures involving skull and facial bones	0.005	0.995	0.000
S04 Injury of cranial nerves	0.005	0.995	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.995	0.005
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.005	0.995	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.005	0.995	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
S20.3 Other superficial injuries of front wall of thorax	0.005	0.995	0.000
S21.9 Open wound of thorax, part unspecified	0.005	0.995	0.001
H17.8 Other corneal scars and opacities	0.005	0.995	0.000
S07 Crushing injury of head	0.005	0.995	0.000
S02.50 Fracture of tooth (closed)	0.005	0.995	0.000
D61 Other aplastic anaemias	0.005	0.995	0.000
H18.6 Keratoconus	0.005	0.995	0.000
H15.8 Other disorders of sclera	0.005	0.995	0.000
V48.4 Person injured while boarding or alighting	0.000	0.995	0.005
S02.4 Fracture of malar and maxillary bones	0.005	0.995	0.000
K56.7 Ileus, unspecified	0.005	0.995	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.005	0.995	0.000
S02.01 Fracture of vault of skull (open)	0.005	0.995	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.005	0.995	0.000
D48.1 Connective and other soft tissue	0.005	0.995	0.000
E85.3 Secondary systemic amyloidosis	0.000	0.995	0.005
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.005	0.995	0.000
S00.4 Superficial injury of ear	0.005	0.995	0.000
H16 Keratitis	0.005	0.995	0.000
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.004	0.995	0.000
S03.0 Dislocation of jaw	0.004	0.995	0.000
S02.3 Fracture of orbital floor	0.004	0.995	0.000
H18.7 Other corneal deformities	0.004	0.995	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.005	0.995	0.000
S06 Intracranial injury	0.004	0.995	0.000
S05 Injury of eye and orbit	0.004	0.995	0.000
H18.2 Other corneal oedema	0.004	0.996	0.000
Y95 Nosocomial condition	0.004	0.996	0.000
S02.2 Fracture of nasal bones	0.004	0.996	0.000
S08.1 Traumatic amputation of ear	0.004	0.996	0.000
H47.3 Other disorders of optic disk	0.004	0.996	0.000
S02.51 Fracture of tooth (open)	0.004	0.996	0.000
E85.8 Other amyloidosis	0.000	0.996	0.004
H49.2 Sixth [abducent] nerve palsy	0.004	0.996	0.000
D72 Other disorders of white blood cells	0.004	0.996	0.000
D61.0 Constitutional aplastic anaemia	0.004	0.996	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.004	0.996	0.001
H15.0 Scleritis	0.004	0.996	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
D62 Acute posthaemorrhagic anaemia	0.004	0.996	0.000
S06.0 Concussion	0.004	0.996	0.000
S08.9 Traumatic amputation of unspecified part of head	0.004	0.996	0.000
S08.8 Traumatic amputation of other parts of head	0.004	0.996	0.000
S08.0 Avulsion of scalp	0.004	0.996	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.004	0.996	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.004	0.996	0.000
S06.2 Diffuse brain injury	0.004	0.996	0.000
S04.5 Injury of facial nerve	0.004	0.996	0.000
D74.9 Methaemoglobinaemia, unspecified	0.004	0.996	0.000
D74.8 Other methaemoglobinaemias	0.004	0.996	0.000
D74.0 Congenital methaemoglobinaemia	0.004	0.996	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.996	0.004
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.996	0.004
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.996	0.004
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.004	0.996	0.000
S03.4 Sprain and strain of jaw	0.004	0.996	0.000
S03.3 Dislocation of other and unspecified parts of head	0.004	0.996	0.000
S02.8 Fractures of other skull and facial bones	0.004	0.996	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.004	0.996	0.000
S04.9 Injury of unspecified cranial nerve	0.004	0.996	0.000
S04.8 Injury of other cranial nerves	0.004	0.996	0.000
S04.7 Injury of accessory nerve	0.004	0.996	0.000
S04.6 Injury of acoustic nerve	0.004	0.996	0.000
S04.4 Injury of abducent nerve	0.004	0.996	0.000
S04.3 Injury of trigeminal nerve	0.004	0.996	0.000
S04.2 Injury of trochlear nerve	0.004	0.996	0.000
S04.1 Injury of oculomotor nerve	0.004	0.996	0.000
S04.0 Injury of optic nerve and pathways	0.004	0.996	0.000
H16.3 Interstitial and deep keratitis	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.004	0.996	0.000
H49.9 Paralytic strabismus, unspecified	0.004	0.996	0.000
S02.1 Fracture of base of skull	0.004	0.996	0.000
H49 Paralytic strabismus	0.004	0.996	0.000
D61.1 Drug-induced aplastic anaemia	0.004	0.996	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.004	0.996	0.000
H47.2 Optic atrophy	0.004	0.996	0.000
S07.9 Crushing injury of head, part unspecified	0.004	0.996	0.000
S07.8 Crushing injury of other parts of head	0.004	0.996	0.000
S07.1 Crushing injury of skull	0.004	0.996	0.000
S07.0 Crushing injury of face	0.004	0.996	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.004	0.996	0.000
D61.8 Other specified aplastic anaemias	0.004	0.996	0.000
D61.3 Idiopathic aplastic anaemia	0.004	0.996	0.000
D61.2 Aplastic anaemia due to other external agents	0.004	0.996	0.000
S03.2 Dislocation of tooth	0.004	0.996	0.000
S01.0 Open wound of scalp	0.004	0.996	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
S03.1 Dislocation of septal cartilage of nose	0.004	0.996	0.000
D72.1 Eosinophilia	0.004	0.996	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
S06.9 Intracranial injury, unspecified	0.004	0.996	0.000
H16.8 Other keratitis	0.004	0.996	0.000
S06.1 Traumatic cerebral oedema	0.004	0.996	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.004	0.996	0.000
H47.1 Papilloedema, unspecified	0.004	0.996	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996	0.000
D63.0 Anaemia in neoplastic disease	0.004	0.996	0.000
D60.8 Other acquired pure red cell aplasias	0.003	0.996	0.000
D60.1 Transient acquired pure red cell aplasia	0.003	0.996	0.000
D60.0 Chronic acquired pure red cell aplasia	0.003	0.996	0.000
X60-X84 Intentional self-harm	0.004	0.996	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.996	0.000
X62.0 Home	0.003	0.996	0.000
X62.7 Farm	0.003	0.996	0.000
X62.6 Industrial and construction area	0.003	0.996	0.000
X62.5 Trade and service area	0.003	0.996	0.000
X62.4 Street and highway	0.003	0.996	0.000
X62.3 Sports and athletics area	0.003	0.996	0.000
X62.2 School, other institution and public administrative area	0.003	0.996	0.000
X62.1 Residential institution	0.003	0.996	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.004	0.996	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.003	0.996	0.000
H47.5 Disorders of other visual pathways	0.003	0.996	0.000
S02.31 Fracture of orbital floor (open)	0.003	0.996	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.996	0.000
H47.6 Disorders of visual cortex	0.003	0.996	0.000
H47.4 Disorders of optic chiasm	0.003	0.996	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.996	0.000
S05.7 Avulsion of eye	0.003	0.996	0.000
F43.0 Acute stress reaction	0.003	0.997	0.000
S00.5 Superficial injury of lip and oral cavity	0.003	0.997	0.000
X62.8 Other specified place	0.003	0.997	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.003	0.997	0.000
Y83.9 Surgical procedure, unspecified	0.003	0.997	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.003	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.003	0.997	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations